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Octreotide acetate works by interacting with the somatostatin receptors via G-protein coupling. The mechanism inhibits the release of several secondary hormones, including GH, glucagon, and insulin. This inhibitory hormone has an impact on both the anterior pituitary and the gastrointestinal system. For instance, it antagonizes the effects of the growth hormone-releasing hormone, and therefore, controls the induction of HGH and IGF-1. Besides, the octreotide acetate function is to suppress the production of TSH (Thyroid-Stimulating Hormone) and adenylyl cyclase. In the GIT, octreotide acetate works to the expression of gastrointestinal and pancreatic hormones, glucagon, insulin, and the exocrine secretory actions. In patients with acromegaly, the treatment normalizes the level of growth hormone and IGF-1. The metabolism of octreotide acetate occurs in the liver.
3. What is Octreotide Acetate used for? Octreotide acetate raw powder has a wide range of therapeutic uses. Its physiological activities are synonymous with that of the endogenous somatostatin hormone. Take, for example, both of them inhibit secretion of growth hormone, glucagon, insulin, cholecystokinin, thyroid-stimulating hormone, and gastrin.
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