What Are The Differences Between Ursodeoxycholic Acid Powder And Chenodeoxycholic acid powder

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What Are The Differences Between Ursodeoxycholic Acid Powder And

What is Chenodeoxycholic Acid(CDCA) Powder?

Chenodeoxycholic Acid Powder(474-25-9) or Chenodiol Powder is an exogenous bile acid that can be consumed to achieve the same benefits as those achieved from endogenous chenodiol. The powder is used therapeutically, primarily for the treatment of gallstones, which are just deposits of hardened bile in the gallbladder.

Chenodiol can also be used in the treatment of other disorders such as issues of bile synthesis and metabolism. It is an FDA-approved medication that is commonly prescribed for liver disorders that, at their core, arise from issues with bile.

What is Ursodeoxycholic Acid(UDCA) Powder?

As mentioned above, Ursodeoxycholic acid powder is a synthetic form of UDCA used to treat patients suffering from various hepatobiliary conditions. Ursodeoxycholic acid powder has been found to be effective in Primary Biliary Cirrhosis and has been shown to improve the survival of patients. To find the best Ursodeoxycholic acid powder and get good price, you maybe need to buy Ursodeoxycholic acid powder wholesale.

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Chenodeoxycholic Acid Powder?

Chenodeoxycholic acid powder and Ursodeoxycholic acid powder are two of the major exogenous bile acids that are prescribed and used for the management of gallstones.

Ursodeoxycholic acid powder Ursodeoxycholic acid powder or ursodiol is a secondary bile acid in the human body, that is synthesized from the modification of bile salts by the gut flora. Unlike chenodeoxycholic acid which is primary bile acid and synthesized in the liver, ursodiol is synthesized in the small intestines. The exogenous ursodeoxycholic acid powder is produced from cholic acid which is extracted from the bovine bile.

Comparison of benefits and function Ursodiol and Chenodiol are used for gallstone dissolution, however, the other uses of the two are not as similar. Ursodiol is also used for the management of primary biliary cholangitis and primary sclerosing cholangitis. Due to its higher safety profile, ursodiol is the bile acid of choice for the treatment of intrahepatic cholestasis of pregnancy.

Major Differences 2

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The major difference between chenodeoxycholic acid powder and ursodeoxycholic acid powder is that the latter is not hepatotoxic and can be used freely whereas the former is hepatotoxic and can cause potentially fatal liver disease. Chenodiol is a primary bile acid and Ursodiol is a secondary bile acid along with being an epimer of chenodiol.

Recent studies that were performed with the purpose of comparing ursodiol and chenodiol found that UDCA was more effective at reducing the size of gallstones at the 3-month mark and 6-month mark. However, after 12 months the efficiency of both chenodiol and ursodiol was balanced out and there were no significant differences between the two. Moreover, it was found that Ursodiol could effectively target and treat large and small gallstones at both, high doses and low doses.

Chenodiol, on the other hand, was only effective at reducing the size of small gallstones at higher doses.

According to a different study, chenodiol at lower doses was associated with an increased incidence of cholecystectomy.

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