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What Can We Get From Cycloastragenol Supplement?
What is Cycloastragenol? Cycloastragenol Cycloastragenol is a triterpenoid saponin compound derived from the root of Astragalus herb. Astragalus membranaceus plant has been used in Traditional Chinese medicine (TCM) for over 2000 years and still being used in herbal preparations. The astragalus herb has been known for its ability to improve the immunity, protect the live, act as a diuretic as well as a possess other health properties such as anti-hypersensitivity, antibacterial, anti-aging and anti-stress benefits. Cycloastragenol commonly known as TA-65 but has also been referred to as Cyclogalagenin, Cyclogalegenin, Cyclogalegigenin, and Astramembrangenin. Cycloastragenol supplement is largely
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known as anti-aging agent, however, other cycloastragenol health benefits include enhancing immune system, anti-inflammatory and anti-oxidative properties.
Cycloastragenol and Astragaloside IV Both cycloastragenol and Astragaloside IV occur naturally in the astragalus plant extract. Astragaloside IV is the primary active ingredient in astragalus membranaceus, however, occurs in minute quantities in the root. The process of extracting these saponins, cycloastragenol and astragaloside IV, is usually difficult due to the high level of purification required. While both cycloastragenol and astragaloside IV are derived from astragalus herb, cycloastragenol can also be obtained from astragaloside IV through hydrolysis process. These two compounds have a similar chemical structure, however, cycloastragenol is lighter in molecular weight than astragaloside IV and is also more bioavailable.
Some potential benefits of cycloastragenol (1)Fighting oxidative stress (2)Cycloastragenol acts as a telomerase activator (3)Cycloastragenol offers protection from UV rays (4)Cycloastragenol inhibits protein glycation (5) Cycloastragenol cancer treatment (6)May protect the heart against damage (7)Better sleep (8)May help fight depression (9)May accelerate wound healing (10)Improve hair health
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Phcoker The Standard Dose of Cycloastragenol
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The standard cycloastragenol dosage is about 10 mg daily. However, since this a fairly new supplement its dosage would largely depend on the use, age and underlying medical conditions. This standard cycloastragenol dosage should be increased in elderly persons of over 60 years to achieve adequate telomere elongation as well as slow the aging process.
Is Cycloastragenol safe? Cycloastragenol powder is generally regarded as safe at certain dosage ranges. However, since it a fairly new supplement the possible cycloastragenol side effects are not yet known. The few cycloastragenol reviews on the said benefits of cycloastragenol are not conclusive enough to warrant it rationale use. In addition, there are concerns that cycloastragenol supplement could accelerate cancer by promoting the growth of tumors. This is a theoretical speculation based on the fact that cycloastragenol main mode of action is through telomere elongation. It is hence thought that it would improve cancer cell growth. It is therefore advisable to avoid giving cycloastragenol to cancer patients until reliable data is available in regards to this speculation and also to avoid any unknown cycloastragenol toxicity.
Where can We Get the Best Cycloastragenol? Well, cycloastragenol powder for sale is readily available online and in various nutritional stores. However, always research for cycloastragenol powder for sale from approved and reputable cycloastragenol suppliers to ensure you get highly purified cycloastragenol.
References [1]Yuan Yao and Maria Luz Fernandez (2017). “Beneficial Effects of Telomerase Activator (TA-65) Against Chronic Disease”. EC Nutrition 6.5: 176-183.
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[2]Wang, J., Wu, M.-L., Cao, S.-P., Cai, H., Zhao, Z.-M., & Song, Y.-H. (2018). Cycloastragenol ameliorates experimental heart damage in rats by promoting myocardial autophagy via inhibition of AKT1-RPS6KB1 signaling. Biomedicine & Pharmacotherapy, 107, 1074–1081. doi: 10.1016/j.biopha.2018.08.016 [3]Sun, C., Jiang, M., Zhang, L., Yang, J., Zhang, G., Du, B., … Yao, J. (2017). Cycloastragenol mediates activation and proliferation suppression in concanavalin A-induced mouse lymphocyte pan-activation model. Immunopharmacology and Immunotoxicology, 39(3), 131–139. doi:10.1080/08923973.2017.1300170. [4]Ip F, C, F, Ng Y, P, An H, J, Dai Y, Pang H, H, Hu Y, Q, Chin A, C, Harley C, B, Wong Y, H, Ip N, Y: Cycloastragenol Is a Potent Telomerase Activator in Neuronal Cells: Implications for Depression Management. Neurosignals 2014; 22: 52-63. doi: 10.1159/000365290. [5]Yu, Yongjie & Zhou, Limin & Yang, Yajun & Liu, Yuyu. (2018). Cycloastragenol: An exciting novel candidate for age- associated diseases (Review). Experimental and Therapeutic Medicine. 16. 10.3892/etm.2018.6501. [6]CYCLOASTRAGENOL POWDER(78574-94-4)
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