Knowledge
Medical Insight: Polodoc
Dr.med. Andreas Krüger is a Swiss board orthopaedic and trauma surgeon in Zurich, who specialises in knee and shoulder surgery. Andi is a second generation of tournament doctors for equine sports, known as Polodoc since 2013
Precision in Decision
Boosting results with use of hyper individual knowledge The correct diagnosis and the ideal treatment for the right patient in the right time frame results in a faster, better and longer performance for the athlete. This is exactly the opposite of a one drug or one treatment fits all approach. Precision medicine helps to better understand environment, lifestyle, and heredity factors that play a role in a player’s or patient’s life. With additional information gained, including through artificial intelligence
and machine learning, will make treatments as effective and safe as possible, or can even indicate how to prevent the illness from starting in the first place.
The challenge
– Identifying which approaches will be effective for which players based on genetic, environmental, and lifestyle factors. – How can we be smarter in decisionmaking? – How can we improve treatment results? – How can a person’s unique genomic portfolio help?
Potential long-term benefits of precision medicine – Wider ability to use players’ genetic and other molecular information as part of routine check-up care for playing. – Improved ability to predict which treatments will work best for specific players. – Better understanding of the underlying mechanisms which cause various diseases/ injuries. – Improved approaches to preventing, diagnosing, and treating a wide range of diseases/injuries. Pharmacogenomics is a part of precision medicine. Pharmacogenomics is the study of how genes affect a person’s response to particular drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that are tailored to variations in a person’s genes.
Overall benefits
Technology can assist with diagnostics & precision
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Polo Times, December 2021 / January 2022
– Shift the emphasis in medicine from reaction to prevention – Predict susceptibility to disease/injury – Improve disease detection – Customize disease-prevention strategies
Mate contains 1.7 % caffeine in fresh leaves
Expert Opinion
Dr.med. Anna Erat, Hirslanden Checkup Center Zurich Like Maté? • Maté contains 1.7 % caffeine in fresh leaves • Caffeine is the most widely consumed psychoactive substance in the world • Caffeine has been proven to be effective in enhancing performance and is not on the WADA doping list any longer • Albeit demographic and social factors have been linked to habitual caffeine consumption, twin studies show a large heritable component • Harvard scientists have identified a genetic propensity for coffee consumption. Two genes were identified that drive people to consume more or less caffeine • Genetic variants of CYP1A2 and AHR determine whether caffeine may be harmful to you • By testing a difference between good and winning performance can be detected • Genetic variants, can determine how fast the body metabolizes caffeine and how and when to use it! Check-up Zentrum Hirslanden Forchstrasse 420 8702 Zollikon CH +41 44 387 20 50 checkup@hirslanden.ch
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