Chapter
13 The Brain and Cranial Nerves PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris
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An Introduction to the Brain and Cranial Nerves The Adult Human Brain Ranges from 750 cc to 2100 cc Contains almost 97% of the body s neural tissue Average weight about 1.4 kg (3 lb)
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The Brain Six Regions of the Brain Cerebrum Cerebellum Diencephalon Mesencephalon Pons Medulla oblongata 3D Peel-Away of the Brain Copyright © 2010 Pearson Education, Inc.
The Brain Cerebrum Largest part of brain Controls higher mental functions Divided into left and right cerebral hemispheres Surface layer of gray matter (neural cortex)
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The Brain Cerebrum Neural cortex Also called cerebral cortex Folded surface increases surface area Elevated ridges (gyri) Shallow depressions (sulci) Deep grooves (fissures)
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The Brain Cerebellum Second largest part of brain Coordinates repetitive body movements Two hemispheres Covered with cerebellar cortex
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The Brain Diencephalon Located under cerebrum and cerebellum Links cerebrum with brain stem Three divisions Left thalamus Right thalamus Hypothalamus
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The Brain Diencephalon Thalamus Relays and processes sensory information
Hypothalamus Hormone production Emotion Autonomic function
Pituitary gland
Major endocrine gland Connected to hypothalamus Via infundibulum (stalk) Interfaces nervous and endocrine systems
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The Brain The Brain Stem Processes information between Spinal cord and cerebrum or cerebellum
Includes Mesencephalon Pons Medulla oblongata
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The Brain The Brain Stem Mesencephalon Also called midbrain Processes sight, sound, and associated reflexes Maintains consciousness
Pons Connects cerebellum to brain stem Is involved in somatic and visceral motor control Copyright © 2010 Pearson Education, Inc.
The Brain The Brain Stem Medulla oblongata Connects brain to spinal cord Relays information Regulates autonomic functions: – heart rate, blood pressure, and digestion
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The Brain
Figure 13–1 An Introduction to Brain Structures and Functions. Copyright © 2010 Pearson Education, Inc.
The Brain Embryological Development Determines organization of brain structures Neural tube Origin of brain Enlarges into three primary brain vesicles – prosencephalon – mesencephalon – rhombencephalon Copyright © 2010 Pearson Education, Inc.
The Brain Five Secondary Brain Vesicles Telencephalon Diencephalon Mesencephalon Metencephalon Myelencephalon
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The Brain Origins of Brain Structures Diencephalon and mesencephalon persist Telencephalon: Becomes cerebrum
Metencephalon Forms cerebellum and pons
Myelencephalon Becomes medulla oblongata Copyright © 2010 Pearson Education, Inc.
The Brain
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The Brain Ventricles of the Brain Origins of ventricles Neural tube encloses neurocoel Neurocoel expands to form chambers (ventricles) lined with ependymal cells
Each cerebral hemisphere contains one large lateral ventricle Separated by a thin medial partition (septum pellucidum)
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The Brain Ventricles of the Brain Third ventricle Ventricle of the diencephalon Lateral ventricles communicate with third ventricle: – via interventricular foramen (foramen of Monro)
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The Brain Ventricles of the Brain Fourth ventricle Extends into medulla oblongata Becomes continuous with central canal of the spinal cord Connects with third ventricle: – via narrow canal in mesencephalon – aqueduct of midbrain Copyright © 2010 Pearson Education, Inc.
The Brain
Figure 13–2 Ventricles of the Brain. Copyright © 2010 Pearson Education, Inc.
The Brain The brain is a large, delicate mass of neural tissue containing internal passageways and chambers filled with cerebrospinal fluid Each of the six major brain regions has specific functions Ascending from the medulla oblongata to the cerebrum, brain functions become more complex and variable Conscious thought and intelligence are produced in the neural cortex of the cerebral hemispheres Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Physical protection Bones of the cranium Cranial meninges Cerebrospinal fluid
Biochemical isolation Blood–brain barrier
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Brain Protection and Support The Cranial Meninges Have three layers: Dura mater Arachnoid mater Pia mater
Are continuous with spinal meninges Protect the brain from cranial trauma
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Brain Protection and Support The Cranial Meninges Dura mater Inner fibrous layer (meningeal layer) Outer fibrous layer (endosteal layer) fused to periosteum Venous sinuses between two layers
Arachnoid mater Covers brain Contacts epithelial layer of dura mater Subarachnoid space: between arachnoid mater and pia mater
Pia mater Attached to brain surface by astrocytes Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Dural Folds Folded inner layer of dura mater Extend into cranial cavity Stabilize and support brain Contain collecting veins (dural sinuses) Falx cerebri, tentorium cerebelli, and falx cerebelli
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Brain Protection and Support Dural Folds Falx cerebri Projects between the cerebral hemispheres Contains superior sagittal sinus and inferior sagittal sinus
Tentorium cerebelli Separates cerebellum and cerebrum Contains transverse sinus
Falx cerebelli Divides cerebellar hemispheres below the tentorium cerebelli Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support
Figure 13–3a The Relationship among the Brain, Cranium, and Meninges. Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support
Figure 13–3b The Relationship among the Brain, Cranium, and Meninges. Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Cerebrospinal Fluid (CSF) Surrounds all exposed surfaces of CNS Interchanges with interstitial fluid of brain Functions of CSF Cushions delicate neural structures Supports brain Transports nutrients, chemical messengers, and waste products Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Cerebrospinal Fluid (CSF) Choroid plexus Specialized ependymal cells and capillaries: – secrete CSF into ventricles – remove waste products from CSF – adjust composition of CSF
Produces about 500 mL of CSF/day
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Brain Protection and Support Cerebrospinal Fluid (CSF) CSF circulates From choroid plexus Through ventricles To central canal of spinal cord Into subarachnoid space around the brain, spinal cord, and cauda equina
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Brain Protection and Support Cerebrospinal Fluid (CSF) CSF in subarachnoid space Arachnoid villi: – extensions of subarachnoid space – extend through dura mater to superior sagittal sinus
Arachnoid granulations: – large clusters of villi – absorb CSF into venous circulation
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Brain Protection and Support
Figure 13–4 The Formation and Circulation of Cerebrospinal Fluid.
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Brain Protection and Support
Figure 13–4a The Formation and Circulation of Cerebrospinal Fluid.
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Brain Protection and Support
Figure 13–4b The Formation and Circulation of Cerebrospinal Fluid.
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Brain Protection and Support Blood Supply to the Brain Supplies nutrients and oxygen to brain Delivered by internal carotid arteries and vertebral arteries Removed from dural sinuses by internal jugular veins
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Brain Protection and Support
Figure 19–22 Arteries of the Neck and Head. Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support
Figure 19–23 Arteries of the Brain. Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support
Figure 19–28 Major Veins of the Head, Neck, and Brain. Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support
Figure 19–28 Major Veins of the Head, Neck, and Brain. Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Cerebrovascular Disease Disorders interfere with blood circulation to brain Stroke or cerebrovascular accident (CVA) Shuts off blood to portion of brain Neurons die
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Brain Protection and Support Blood–Brain Barrier Isolates CNS neural tissue from general circulation Formed by network of tight junctions Between endothelial cells of CNS capillaries Lipid-soluble compounds (O2, CO2), steroids, and prostaglandins diffuse into interstitial fluid of brain and spinal cord Astrocytes control blood–brain barrier by releasing chemicals that control permeability of endothelium Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Blood–CSF Barrier Formed by special ependymal cells Surround capillaries of choroid plexus Limits movement of compounds transferred Allows chemical composition of blood and CSF to differ
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Brain Protection and Support Four Breaks in the BBB Portions of hypothalamus Secrete hypothalamic hormones
Posterior lobe of pituitary gland Secretes hormones ADH and oxytocin
Pineal glands Pineal secretions
Choroid plexus Where special ependymal cells maintain blood– CSF barrier Copyright © 2010 Pearson Education, Inc.
Brain Protection and Support Meninges stabilize brain in cranial cavity Cerebrospinal fluid protects against sudden movement CSF provides nutrients and removes wastes Blood–brain barrier and blood–CSF barrier Selectively isolate brain from chemicals in blood that might disrupt neural function
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The Medulla Oblongata The Medulla Oblongata Allows brain and spinal cord to communicate Coordinates complex autonomic reflexes Controls visceral functions Nuclei in the Medulla Autonomic nuclei: control visceral activities Sensory and motor nuclei: of cranial nerves Relay stations: along sensory and motor pathways Copyright © 2010 Pearson Education, Inc.
The Medulla Oblongata
Figure 13–5a The Diencephalon and Brain Stem. Copyright © 2010 Pearson Education, Inc.
The Medulla Oblongata
Figure 13–5b The Diencephalon and Brain Stem. Copyright © 2010 Pearson Education, Inc.
The Medulla Oblongata
Figure 13–5c The Diencephalon and Brain Stem. Copyright © 2010 Pearson Education, Inc.
The Medulla Oblongata The Medulla Oblongata Includes three groups of nuclei Autonomic nuclei Sensory and motor nuclei of cranial nerves Relay stations along sensory and motor pathways
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The Medulla Oblongata Autonomic Nuclei of the Medulla Oblongata Reticular formation Gray matter with embedded nuclei Regulates autonomic functions
Reflex centers Control peripheral systems: – cardiovascular centers: » cardiac center » control blood flow through peripheral tissues – respiratory rhythmicity centers sets pace for respiratory movements Copyright © 2010 Pearson Education, Inc.
The Medulla Oblongata Sensory and Motor Nuclei of the Medulla Oblongata Associated with 5 of 12 cranial nerves (VIII, IX, X, XI, XII)
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The Medulla Oblongata Relay Stations of the Medulla Oblongata Nucleus gracilis and nucleus cuneatus Pass somatic sensory information to thalamus
Solitary nucleus Receives visceral sensory information
Olivary nuclei (olives) Relay information about somatic motor commands
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The Medulla Oblongata
Figure 13–6a The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.
The Medulla Oblongata
Figure 13–6b The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.
The Pons The Pons Links cerebellum with mesencephalon, diencephalon, cerebrum, and spinal cord Sensory and motor nuclei of cranial nerves V, VI, VII, VIII
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The Pons The Pons Nuclei involved with respiration Apneustic center and pneumotaxic center: – modify respiratory rhythmicity center activity
Nuclei and tracts Process and relay information to and from cerebellum Ascending, descending, and transverse tracts: – transverse fibers (axons): » link nuclei of pons with opposite cerebellar hemisphere Copyright © 2010 Pearson Education, Inc.
The Pons
Figure 13–6a The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.
The Pons
Figure 13–6b The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.
The Pons
Figure 13–6c The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.
The Pons
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The Pons
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The Cerebellum Functions of the Cerebellum Adjusts postural muscles Fine-tunes conscious and subconscious movements
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The Cerebellum Structures of the Cerebellum Folia Surface of cerebellum Highly folded neural cortex
Anterior and posterior lobes Separated by primary fissure
Cerebellar hemispheres: Separated at midline by vermis
Vermis Narrow band of cortex
Flocculonodular lobe Below fourth ventricle Copyright © 2010 Pearson Education, Inc.
The Cerebellum Structures of the Cerebellum Purkinje cells Large, branched cells Found in cerebellar cortex Receive input from up to 200,000 synapses
Arbor vitae Highly branched, internal white matter of cerebellum Cerebellar nuclei: embedded in arbor vitae: – relay information to Purkinje cells Copyright © 2010 Pearson Education, Inc.
The Cerebellum Structures of the Cerebellum The peduncles Tracts link cerebellum with brain stem, cerebrum, and spinal cord: – superior cerebellar peduncles – middle cerebellar peduncles – inferior cerebellar peduncles
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The Cerebellum Disorders of the Cerebellum Ataxia Damage from trauma or stroke Intoxication (temporary impairment) Disturbs muscle coordination
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The Cerebellum
Figure 13–7a The Cerebellum. Copyright © 2010 Pearson Education, Inc.
The Cerebellum
Figure 13–7b The Cerebellum. Copyright © 2010 Pearson Education, Inc.
The Cerebellum
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The Mesencephalon Structures of the Mesencephalon Tectum Two pairs of sensory nuclei (corpora quadrigemina): – superior colliculus (visual) – inferior colliculus (auditory)
Tegmentum Red nucleus (many blood vessels) Substantia nigra (pigmented gray matter)
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The Mesencephalon Structures of the Mesencephalon Cerebral peduncles Nerve fiber bundles on ventrolateral surfaces Contain: – descending fibers to cerebellum – motor command fibers
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The Mesencephalon
Figure 13–8a The Mesencephalon. Copyright © 2010 Pearson Education, Inc.
The Mesencephalon
Figure 13–8b The Mesencephalon. Copyright © 2010 Pearson Education, Inc.
The Mesencephalon
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The Diencephalon Integrates sensory information and motor commands Thalamus, epithalamus, and hypothalamus The pineal gland Found in posterior epithalamus Secretes hormone melatonin
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The Diencephalon The Thalamus Filters ascending sensory information for primary sensory cortex Relays information between basal nuclei and cerebral cortex The third ventricle Separates left thalamus and right thalamus Interthalamic adhesion (or intermediate mass): – projection of gray matter – extends into ventricle from each side Copyright © 2010 Pearson Education, Inc.
The Diencephalon The Thalamus Thalamic nuclei Are rounded masses that form thalamus Relay sensory information to basal nuclei and cerebral cortex
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The Diencephalon Five Groups of Thalamic Nuclei Anterior group Anterior nuclei Part of limbic system (emotions)
Medial group Provides awareness of emotional states
Ventral group Relays sensory information Copyright © 2010 Pearson Education, Inc.
The Diencephalon Five Groups of Thalamic Nuclei Posterior group Pulvinar nucleus (sensory) Lateral geniculate nucleus (visual) Medial geniculate nucleus (auditory)
Lateral group Affects emotional states Integrates sensory information Copyright © 2010 Pearson Education, Inc.
The Diencephalon
Figure 13–9 The Thalamus. Copyright © 2010 Pearson Education, Inc.
The Diencephalon
Figure 13–9a The Thalamus. Copyright © 2010 Pearson Education, Inc.
The Diencephalon
Figure 13–9b The Thalamus. Copyright © 2010 Pearson Education, Inc.
The Diencephalon
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The Diencephalon The Hypothalamus Mamillary bodies Process olfactory and other sensory information Control reflex eating movements
Infundibulum A narrow stalk Connects hypothalamus to pituitary gland
Tuberal area Located between the infundibulum and mamillary bodies Helps control pituitary gland function
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The Diencephalon
Figure 13–10a The Hypothalamus in Sagittal Section. Copyright © 2010 Pearson Education, Inc.
The Diencephalon
Figure 13–10b The Hypothalamus in Sagittal Section. Copyright © 2010 Pearson Education, Inc.
The Diencephalon Eight Functions of the Hypothalamus Provides subconscious control of skeletal muscle Controls autonomic function Coordinates activities of nervous and endocrine systems Secretes hormones Antidiuretic hormone (ADH) by supraoptic nucleus Oxytocin (OT; OXT) by paraventricular nucleus
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The Diencephalon Eight Functions of the Hypothalamus Produces emotions and behavioral drives The feeding center (hunger) The thirst center (thirst)
Coordinates voluntary and autonomic functions Regulates body temperature Preoptic area of hypothalamus
Controls circadian rhythms (day–night cycles) Suprachiasmatic nucleus Copyright © 2010 Pearson Education, Inc.
The Diencephalon
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The Limbic System The Limbic System Is a functional grouping that Establishes emotional states Links conscious functions of cerebral cortex with autonomic functions of brain stem Facilitates memory storage and retrieval
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The Limbic System Components of the Limbic System Amygdaloid body Acts as interface between the limbic system, the cerebrum, and various sensory systems
Limbic lobe of cerebral hemisphere Cingulate gyrus Dentate gyrus Parahippocampal gyrus Hippocampus Copyright © 2010 Pearson Education, Inc.
The Limbic System Components of the Limbic System Fornix Tract of white matter Connects hippocampus with hypothalamus
Anterior nucleus of the thalamus Relays information from mamillary body to cingulate gyrus
Reticular formation Stimulation or inhibition affects emotions (rage, fear, pain, sexual arousal, pleasure) Copyright © 2010 Pearson Education, Inc.
The Limbic System
Figure 13–11a The Limbic System. Copyright © 2010 Pearson Education, Inc.
The Limbic System
Figure 13–11b The Limbic System. Copyright © 2010 Pearson Education, Inc.
The Limbic System
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The Cerebrum The Cerebrum Is the largest part of the brain Controls all conscious thoughts and intellectual functions Processes somatic sensory and motor information
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The Cerebrum Gray matter In cerebral cortex and basal nuclei
White matter Deep to basal cortex Around basal nuclei
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The Cerebrum Structures of the Cerebrum Gyri of neural cortex Increase surface area (number of cortical neurons)
Insula (island) of cortex Lies medial to lateral sulcus
Longitudinal fissure Separates cerebral hemispheres
Lobes Divisions of hemispheres Copyright © 2010 Pearson Education, Inc.
The Cerebrum Structures of the Cerebrum Central sulcus divides Anterior frontal lobe from posterior parietal lobe
Lateral sulcus divides Frontal lobe from temporal lobe
Parieto-occipital sulcus divides Parietal lobe from occipital lobe
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The Cerebrum
Figure 13–12a The Brain in Lateral View. Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–12b The Brain in Lateral View. Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–12c The Brain in Lateral View. Copyright © 2010 Pearson Education, Inc.
The Cerebrum Three Functional Principles of the Cerebrum Each cerebral hemisphere receives sensory information from, and sends motor commands to, the opposite side of the body The two hemispheres have different functions, although their structures are alike Correspondence between a specific function and a specific region of cerebral cortex is not precise Copyright © 2010 Pearson Education, Inc.
The Cerebrum White Matter of the Cerebrum Association fibers Commissural fibers Projection fibers
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The Cerebrum White Matter of the Cerebrum Association fibers Connections within one hemisphere: – arcuate fibers: » are short fibers » connect one gyrus to another
– longitudinal fasciculi: » are longer bundles » connect frontal lobe to other lobes in same hemisphere
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The Cerebrum White Matter of the Cerebrum Commissural fibers Bands of fibers connecting two hemispheres: – corpus callosum – anterior commissure
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The Cerebrum White Matter of the Cerebrum Projection fibers Pass through diencephalon Link cerebral cortex with: – diencephalon, brain stem, cerebellum, and spinal cord
Internal capsule: – all ascending and descending projection fibers
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The Cerebrum
Figure 13–13a Fibers of the White Matter of the Cerebrum. Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–13b Fibers of the White Matter of the Cerebrum. Copyright © 2010 Pearson Education, Inc.
The Cerebrum The Basal Nuclei Also called cerebral nuclei Are masses of gray matter Are embedded in white matter of cerebrum Direct subconscious activities
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The Cerebrum Structures of Basal Nuclei Caudate nucleus Curving, slender tail
Lentiform nucleus Globus pallidus Putamen
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The Cerebrum
Figure 13–14a The Basal Nuclei. Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–14b The Basal Nuclei. Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–14c The Basal Nuclei. Copyright © 2010 Pearson Education, Inc.
The Cerebrum Functions of Basal Nuclei Involved with The subconscious control of skeletal muscle tone The coordination of learned movement patterns (walking, lifting)
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The Cerebrum Motor and Sensory Areas of the Cortex Central sulcus separates motor and sensory areas Motor areas Precentral gyrus of frontal lobe: – directs voluntary movements
Primary motor cortex: – is the surface of precentral gyrus
Pyramidal cells: – are neurons of primary motor cortex Copyright © 2010 Pearson Education, Inc.
The Cerebrum Motor and Sensory Areas of the Cortex Sensory areas Postcentral gyrus of parietal lobe: – receives somatic sensory information (touch, pressure, pain, vibration, taste, and temperature)
Primary sensory cortex: – surface of postcentral gyrus
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The Cerebrum Special Sensory Cortexes Visual cortex Information from sight receptors
Auditory cortex Information from sound receptors
Olfactory cortex Information from odor receptors
Gustatory cortex Information from taste receptors Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–15a Motor and Sensory Regions of the Cerebral Cortex. Copyright © 2010 Pearson Education, Inc.
The Cerebrum Association Areas Sensory association areas Monitor and interpret arriving information at sensory areas of cortex
Somatic motor association area (premotor cortex) Coordinates motor responses (learned movements)
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The Cerebrum Sensory Association Areas Somatic sensory association area Interprets input to primary sensory cortex (e.g., recognizes and responds to touch)
Visual association area Interprets activity in visual cortex
Auditory association area Monitors auditory cortex
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The Cerebrum Integrative Centers Are located in lobes and cortical areas of both cerebral hemispheres Receive information from association areas Direct complex motor or analytical activities
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The Cerebrum General Interpretive Area Also called Wernicke area Present in only one hemisphere Receives information from all sensory association areas Coordinates access to complex visual and auditory memories
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The Cerebrum Other Integrative Areas Speech center Is associated with general interpretive area Coordinates all vocalization functions
Prefrontal cortex of frontal lobe Integrates information from sensory association areas Performs abstract intellectual activities (e.g., predicting consequences of actions) Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–15b Motor and Sensory Regions of the Cerebral Cortex. Copyright © 2010 Pearson Education, Inc.
The Cerebrum Interpretive Areas of Cortex Brodmann areas Patterns of cellular organization in cerebral cortex
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The Cerebrum
Figure 13–15c Motor and Sensory Regions of the Cerebral Cortex. Copyright © 2010 Pearson Education, Inc.
The Cerebrum
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The Cerebrum Hemispheric Lateralization Functional differences between left and right hemispheres Each cerebral hemisphere performs certain functions that are not ordinarily performed by the opposite hemisphere
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The Cerebrum The Left Hemisphere In most people, left brain (dominant hemisphere) controls Reading, writing, and math Decision making Speech and language
The Right Hemisphere Right cerebral hemisphere relates to Senses (touch, smell, sight, taste, feel) Recognition (faces, voice inflections) Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–16 Hemispheric Lateralization. Copyright © 2010 Pearson Education, Inc.
The Cerebrum Monitoring Brain Activity Brain activity is assessed by an electroencephalogram (EEG) Electrodes are placed on the skull Patterns of electrical activity (brain waves) are printed out
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The Cerebrum Four Categories of Brain Waves Alpha waves Found in healthy, awake adults at rest with eyes closed
Beta waves Higher frequency Found in adults concentrating or mentally stressed
Theta waves Found in children Found in intensely frustrated adults May indicate brain disorder in adults
Delta waves During sleep Found in awake adults with brain damage Copyright © 2010 Pearson Education, Inc.
The Cerebrum
Figure 13–17a-d Brain Waves. Copyright © 2010 Pearson Education, Inc.
The Cerebrum Synchronization A pacemaker mechanism Synchronizes electrical activity between hemispheres
Brain damage can cause desynchronization
Seizure Is a temporary cerebral disorder Changes the electroencephalogram Symptoms depend on regions affected Copyright © 2010 Pearson Education, Inc.
Cranial Nerves 12 pairs connected to brain Four Classifications of Cranial Nerves Sensory nerves: carry somatic sensory information, including touch, pressure, vibration, temperature, and pain Special sensory nerves: carry sensations such as smell, sight, hearing, balance Motor nerves: axons of somatic motor neurons Mixed nerves: mixture of motor and sensory fibers Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Cranial nerves are classified by primary functions May also have important secondary functions Distributing autonomic fibers to peripheral ganglia
The 12 cranial nerve groups are identified by Primary function Origin Pathway Destination Copyright © 2010 Pearson Education, Inc.
Cranial Nerves
Figure 13–18 Origins of the Cranial Nerves. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Olfactory Nerves (I) Primary function Special sensory (smell)
Origin Receptors of olfactory epithelium
Pathway Olfactory foramina in cribriform plate of ethmoid
Destination Olfactory bulbs
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Cranial Nerves Olfactory Nerve Structures Olfactory bulbs Located on either side of crista galli
Olfactory tracts Axons of postsynaptic neurons Leading to cerebrum
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Cranial Nerves
Figure 13–19 The Olfactory Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Optic Nerves (II) Primary function Special sensory (vision)
Origin Retina of eye
Pathway Optic canals of sphenoid
Destination Diencephalon via optic chiasm
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Cranial Nerves Optic Nerve Structures Optic chiasm Where sensory fibers converge And cross to opposite side of brain
Optic tracts Reorganized axons Leading to lateral geniculate nuclei
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Cranial Nerves
Figure 13–20 The Optic Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Oculomotor Nerves (III) Primary function Motor (eye movements)
Origin Mesencephalon
Pathway Superior orbital fissures of sphenoid
Destination Somatic motor: – superior, inferior, and medial rectus muscles – inferior oblique muscle – levator palpebrae superioris muscle
Visceral motor: – intrinsic eye muscles Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Oculomotor Nerve Structures Oculomotor nerve Controls four of six eye-movement muscles Delivers autonomic fibers to ciliary ganglion: – ciliary ganglion: controls intrinsic muscles of iris and lens
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Cranial Nerves The Trochlear Nerves (IV) Primary function Motor (eye movements)
Origin Mesencephalon
Pathway Superior orbital fissure of sphenoid
Destination Superior oblique muscle
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Cranial Nerves The Abducens Nerves (VI) Primary function Motor (eye movements)
Origin Pons
Pathway Superior orbital fissures of sphenoid
Destination Lateral rectus muscle Copyright © 2010 Pearson Education, Inc.
Cranial Nerves
Figure 13–21 Cranial Nerves Controlling the Extra-Ocular Muscles. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Trigeminal Nerves (V) Primary function Mixed (sensory and motor) to face
Origin Ophthalmic branch (sensory): – orbital structures – nasal cavity – skin of forehead, upper eyelid, and eyebrow – part of nose
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Cranial Nerves The Trigeminal Nerves (V) Origin Maxillary branch (sensory): – lower eyelid – upper lip, gums, and teeth – cheek and nose – palate and part of pharynx
Mandibular branch (sensory): – lower gums, teeth, and lips – palate and part of tongue
Mandibular branch (motor): – motor nuclei of pons Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Trigeminal Nerves (V) Pathway Ophthalmic branch: – superior orbital fissure
Maxillary branch: – foramen rotundum
Mandibular branch: – foramen ovale
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Cranial Nerves The Trigeminal Nerves (V) Destination Sensory nerves: – sensory nuclei in pons
Motor nerves of mandibular branch: – muscles of mastication
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Cranial Nerves Trigeminal Nerve Structures Trigeminal nerves Largest cranial nerves With three major branches
Semilunar ganglion Contains cell bodies of sensory neurons
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Cranial Nerves
Figure 13–22 The Trigeminal Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Facial Nerves (VII) Primary function Mixed (sensory and motor) to face
Origin Sensory: – taste receptors on anterior 2/3 of tongue
Motor: – motor nuclei of pons
Pathway Internal acoustic meatus to facial canals (stylomastoid foramina) Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Facial Nerves (VII) Destination Sensory: – sensory nuclei of pons
Somatic motor: – muscles of facial expression
Visceral motor: – tear and nasal mucous glands – submandibular and sublingual salivary glands Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Facial Nerve Structures Facial nerve branches Temporal Zygomatic Buccal Mandibular Cervical branches
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Cranial Nerves Facial Nerve Structures Geniculate ganglia Hold cell bodies of sensory neurons
Pterygopalatine ganglia Postganglionic fibers innervate glands (lacrimal, nasal cavity, and pharynx)
Submandibular ganglia Innervate salivary glands
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Cranial Nerves
Figure 13–23a The Facial Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves
Figure 13–23b The Facial Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Vestibulocochlear Nerves (VIII) Primary function: special sensory Vestibular branch: – balance and equilibrium
Cochlear branch: – hearing
Origin Receptors of inner ear
Pathway Internal acoustic meatus of temporal bones
Destination Vestibular and cochlear nuclei of pons and medulla oblongata Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Vestibulocochlear Nerve Structures Vestibular branch Originates at receptors of vestibule (balance) Connects to vestibular nuclei of pons and medulla oblongata
Cochlear branch Originates at sensors of cochlea (hearing) Connects with cochlear nuclei of pons and medulla oblongata
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Cranial Nerves
Figure 13–24 The Vestibulocochlear Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Glossopharyngeal Nerves (IX) Primary function Mixed (sensory and motor) to head and neck
Origins Sensory: – posterior 1/3 of tongue – part of pharynx and palate – carotid arteries
Motor: – motor nuclei of medulla oblongata Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Glossopharyngeal Nerves (IX) Pathway Jugular foramina between occipital and temporal bones
Destination Sensory: – sensory nuclei of medulla oblongata
Somatic motor: – nerves involved in swallowing
Visceral motor: – parotid salivary gland Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Glossopharyngeal Nerve Structures Superior and inferior ganglion Sensory neurons of tongue and pharynx
Otic ganglion Synapse visceral motor fibers
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Cranial Nerves
Figure 13–25 The Glossopharyngeal Nerve. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Vagus Nerves (X) Primary function Mixed (sensory and motor) Widely distributed in thorax and abdomen
Origins Sensory: – part of pharynx – auricle and external acoustic meatus – diaphragm – visceral organs of thoracic and abdominopelvic cavities
Motor: – motor nuclei in medulla oblongata Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Vagus Nerves (X) Pathway Jugular foramina Between occipital and temporal bones
Destination Sensory: – sensory nuclei and autonomic centers of medulla oblongata
Visceral motor: – muscles of the palate and pharynx – muscles of the digestive, respiratory, and cardiovascular systems in thoracic and abdominal cavities Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Vagus Nerve Structures Vagus nerves Branch and radiate extensively
Superior (jugular) ganglion and inferior (nodose) ganglion Hold sensory neurons
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Cranial Nerves
Figure 13–26 The Vagus Nerve.
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Cranial Nerves
Figure 13–26 The Vagus Nerve.
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Cranial Nerves The Accessory Nerves (XI) Primary function Motor to muscles of neck and upper back
Origin Motor nuclei of spinal cord and medulla oblongata
Pathway Jugular foramina between occipital and temporal bones
Destination Internal branch: – voluntary muscles of palate, pharynx, and larynx
External branch: – sternocleidomastoid and trapezius muscles Copyright © 2010 Pearson Education, Inc.
Cranial Nerves Accessory Nerve Structures Spinal root Motor fibers that originate in anterior gray horns of first five cervical segments of spinal cord
Cranial root Motor fibers that originate in medulla oblongata
Internal branch Joins the vagus nerve
External branch Controls muscles of neck and back Copyright © 2010 Pearson Education, Inc.
Cranial Nerves The Hypoglossal Nerves (XII) Primary function Motor (tongue movements)
Origin Motor nuclei of medulla oblongata
Pathway Hypoglossal canals of occipital bone
Destination Muscles of tongue Copyright © 2010 Pearson Education, Inc.
Cranial Nerves
Figure 13–27 The Accessory and Hypoglossal Nerves. Copyright © 2010 Pearson Education, Inc.
Cranial Nerves
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Cranial Nerves
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Cranial Reflexes Cranial Reflexes Monosynaptic and polysynaptic reflex arcs Involve sensory and motor fibers of cranial nerves Clinically useful to check cranial nerve or brain damage
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Cranial Reflexes
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