AP-Ch13

Page 1

Chapter

13 The Brain and Cranial Nerves PowerPoint® Lecture Slides prepared by Jason LaPres Lone Star College - North Harris

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An Introduction to the Brain and Cranial Nerves   The Adult Human Brain   Ranges from 750 cc to 2100 cc   Contains almost 97% of the body s neural tissue   Average weight about 1.4 kg (3 lb)

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The Brain   Six Regions of the Brain   Cerebrum   Cerebellum   Diencephalon   Mesencephalon   Pons   Medulla oblongata 3D Peel-Away of the Brain Copyright © 2010 Pearson Education, Inc.


The Brain   Cerebrum   Largest part of brain   Controls higher mental functions   Divided into left and right cerebral hemispheres   Surface layer of gray matter (neural cortex)

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The Brain   Cerebrum   Neural cortex   Also called cerebral cortex   Folded surface increases surface area   Elevated ridges (gyri)   Shallow depressions (sulci)   Deep grooves (fissures)

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The Brain   Cerebellum   Second largest part of brain   Coordinates repetitive body movements   Two hemispheres   Covered with cerebellar cortex

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The Brain   Diencephalon   Located under cerebrum and cerebellum   Links cerebrum with brain stem   Three divisions   Left thalamus   Right thalamus   Hypothalamus

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The Brain   Diencephalon   Thalamus   Relays and processes sensory information

  Hypothalamus   Hormone production   Emotion   Autonomic function

  Pituitary gland       

Major endocrine gland Connected to hypothalamus Via infundibulum (stalk) Interfaces nervous and endocrine systems

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The Brain   The Brain Stem   Processes information between   Spinal cord and cerebrum or cerebellum

  Includes   Mesencephalon   Pons   Medulla oblongata

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The Brain   The Brain Stem   Mesencephalon   Also called midbrain   Processes sight, sound, and associated reflexes   Maintains consciousness

  Pons   Connects cerebellum to brain stem   Is involved in somatic and visceral motor control Copyright © 2010 Pearson Education, Inc.


The Brain   The Brain Stem   Medulla oblongata   Connects brain to spinal cord   Relays information   Regulates autonomic functions: –  heart rate, blood pressure, and digestion

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The Brain

Figure 13–1 An Introduction to Brain Structures and Functions. Copyright © 2010 Pearson Education, Inc.


The Brain   Embryological Development   Determines organization of brain structures   Neural tube   Origin of brain   Enlarges into three primary brain vesicles – prosencephalon – mesencephalon – rhombencephalon Copyright © 2010 Pearson Education, Inc.


The Brain   Five Secondary Brain Vesicles   Telencephalon   Diencephalon   Mesencephalon   Metencephalon   Myelencephalon

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The Brain   Origins of Brain Structures   Diencephalon and mesencephalon persist   Telencephalon:   Becomes cerebrum

  Metencephalon   Forms cerebellum and pons

  Myelencephalon   Becomes medulla oblongata Copyright © 2010 Pearson Education, Inc.


The Brain

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The Brain   Ventricles of the Brain   Origins of ventricles   Neural tube encloses neurocoel   Neurocoel expands to form chambers (ventricles) lined with ependymal cells

  Each cerebral hemisphere contains one large lateral ventricle   Separated by a thin medial partition (septum pellucidum)

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The Brain   Ventricles of the Brain   Third ventricle   Ventricle of the diencephalon   Lateral ventricles communicate with third ventricle: –  via interventricular foramen (foramen of Monro)

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The Brain   Ventricles of the Brain   Fourth ventricle   Extends into medulla oblongata   Becomes continuous with central canal of the spinal cord   Connects with third ventricle: –  via narrow canal in mesencephalon –  aqueduct of midbrain Copyright © 2010 Pearson Education, Inc.


The Brain

Figure 13–2 Ventricles of the Brain. Copyright © 2010 Pearson Education, Inc.


The Brain   The brain is a large, delicate mass of neural tissue containing internal passageways and chambers filled with cerebrospinal fluid   Each of the six major brain regions has specific functions   Ascending from the medulla oblongata to the cerebrum, brain functions become more complex and variable   Conscious thought and intelligence are produced in the neural cortex of the cerebral hemispheres Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Physical protection   Bones of the cranium   Cranial meninges   Cerebrospinal fluid

  Biochemical isolation   Blood–brain barrier

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Brain Protection and Support   The Cranial Meninges   Have three layers:   Dura mater   Arachnoid mater   Pia mater

  Are continuous with spinal meninges   Protect the brain from cranial trauma

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Brain Protection and Support   The Cranial Meninges   Dura mater   Inner fibrous layer (meningeal layer)   Outer fibrous layer (endosteal layer) fused to periosteum   Venous sinuses between two layers

  Arachnoid mater   Covers brain   Contacts epithelial layer of dura mater   Subarachnoid space: between arachnoid mater and pia mater

  Pia mater   Attached to brain surface by astrocytes Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Dural Folds   Folded inner layer of dura mater   Extend into cranial cavity   Stabilize and support brain   Contain collecting veins (dural sinuses)   Falx cerebri, tentorium cerebelli, and falx cerebelli

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Brain Protection and Support   Dural Folds   Falx cerebri   Projects between the cerebral hemispheres   Contains superior sagittal sinus and inferior sagittal sinus

  Tentorium cerebelli   Separates cerebellum and cerebrum   Contains transverse sinus

  Falx cerebelli   Divides cerebellar hemispheres below the tentorium cerebelli Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support

Figure 13–3a The Relationship among the Brain, Cranium, and Meninges. Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support

Figure 13–3b The Relationship among the Brain, Cranium, and Meninges. Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Cerebrospinal Fluid (CSF)   Surrounds all exposed surfaces of CNS   Interchanges with interstitial fluid of brain   Functions of CSF   Cushions delicate neural structures   Supports brain   Transports nutrients, chemical messengers, and waste products Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Cerebrospinal Fluid (CSF)   Choroid plexus   Specialized ependymal cells and capillaries: –  secrete CSF into ventricles –  remove waste products from CSF –  adjust composition of CSF

  Produces about 500 mL of CSF/day

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Brain Protection and Support   Cerebrospinal Fluid (CSF)   CSF circulates   From choroid plexus   Through ventricles   To central canal of spinal cord   Into subarachnoid space around the brain, spinal cord, and cauda equina

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Brain Protection and Support   Cerebrospinal Fluid (CSF)   CSF in subarachnoid space   Arachnoid villi: –  extensions of subarachnoid space –  extend through dura mater to superior sagittal sinus

  Arachnoid granulations: –  large clusters of villi –  absorb CSF into venous circulation

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Brain Protection and Support

Figure 13–4 The Formation and Circulation of Cerebrospinal Fluid.

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Brain Protection and Support

Figure 13–4a The Formation and Circulation of Cerebrospinal Fluid.

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Brain Protection and Support

Figure 13–4b The Formation and Circulation of Cerebrospinal Fluid.

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Brain Protection and Support   Blood Supply to the Brain   Supplies nutrients and oxygen to brain   Delivered by internal carotid arteries and vertebral arteries   Removed from dural sinuses by internal jugular veins

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Brain Protection and Support

Figure 19–22 Arteries of the Neck and Head. Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support

Figure 19–23 Arteries of the Brain. Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support

Figure 19–28 Major Veins of the Head, Neck, and Brain. Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support

Figure 19–28 Major Veins of the Head, Neck, and Brain. Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Cerebrovascular Disease   Disorders interfere with blood circulation to brain   Stroke or cerebrovascular accident (CVA)   Shuts off blood to portion of brain   Neurons die

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Brain Protection and Support   Blood–Brain Barrier   Isolates CNS neural tissue from general circulation   Formed by network of tight junctions   Between endothelial cells of CNS capillaries   Lipid-soluble compounds (O2, CO2), steroids, and prostaglandins diffuse into interstitial fluid of brain and spinal cord   Astrocytes control blood–brain barrier by releasing chemicals that control permeability of endothelium Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Blood–CSF Barrier   Formed by special ependymal cells   Surround capillaries of choroid plexus   Limits movement of compounds transferred   Allows chemical composition of blood and CSF to differ

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Brain Protection and Support   Four Breaks in the BBB   Portions of hypothalamus   Secrete hypothalamic hormones

  Posterior lobe of pituitary gland   Secretes hormones ADH and oxytocin

  Pineal glands   Pineal secretions

  Choroid plexus   Where special ependymal cells maintain blood– CSF barrier Copyright © 2010 Pearson Education, Inc.


Brain Protection and Support   Meninges stabilize brain in cranial cavity   Cerebrospinal fluid protects against sudden movement   CSF provides nutrients and removes wastes   Blood–brain barrier and blood–CSF barrier   Selectively isolate brain from chemicals in blood that might disrupt neural function

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The Medulla Oblongata   The Medulla Oblongata   Allows brain and spinal cord to communicate   Coordinates complex autonomic reflexes   Controls visceral functions   Nuclei in the Medulla   Autonomic nuclei: control visceral activities   Sensory and motor nuclei: of cranial nerves   Relay stations: along sensory and motor pathways Copyright © 2010 Pearson Education, Inc.


The Medulla Oblongata

Figure 13–5a The Diencephalon and Brain Stem. Copyright © 2010 Pearson Education, Inc.


The Medulla Oblongata

Figure 13–5b The Diencephalon and Brain Stem. Copyright © 2010 Pearson Education, Inc.


The Medulla Oblongata

Figure 13–5c The Diencephalon and Brain Stem. Copyright © 2010 Pearson Education, Inc.


The Medulla Oblongata   The Medulla Oblongata   Includes three groups of nuclei   Autonomic nuclei   Sensory and motor nuclei of cranial nerves   Relay stations along sensory and motor pathways

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The Medulla Oblongata   Autonomic Nuclei of the Medulla Oblongata   Reticular formation   Gray matter with embedded nuclei   Regulates autonomic functions

  Reflex centers   Control peripheral systems: –  cardiovascular centers: »  cardiac center »  control blood flow through peripheral tissues –  respiratory rhythmicity centers sets pace for respiratory movements Copyright © 2010 Pearson Education, Inc.


The Medulla Oblongata   Sensory and Motor Nuclei of the Medulla Oblongata  Associated with 5 of 12 cranial nerves (VIII, IX, X, XI, XII)

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The Medulla Oblongata   Relay Stations of the Medulla Oblongata   Nucleus gracilis and nucleus cuneatus   Pass somatic sensory information to thalamus

  Solitary nucleus   Receives visceral sensory information

  Olivary nuclei (olives)   Relay information about somatic motor commands

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The Medulla Oblongata

Figure 13–6a The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.


The Medulla Oblongata

Figure 13–6b The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.


The Pons   The Pons   Links cerebellum with mesencephalon, diencephalon, cerebrum, and spinal cord   Sensory and motor nuclei of cranial nerves V, VI, VII, VIII

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The Pons   The Pons   Nuclei involved with respiration   Apneustic center and pneumotaxic center: –  modify respiratory rhythmicity center activity

  Nuclei and tracts   Process and relay information to and from cerebellum   Ascending, descending, and transverse tracts: –  transverse fibers (axons): »  link nuclei of pons with opposite cerebellar hemisphere Copyright © 2010 Pearson Education, Inc.


The Pons

Figure 13–6a The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.


The Pons

Figure 13–6b The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.


The Pons

Figure 13–6c The Medulla Oblongata and Pons. Copyright © 2010 Pearson Education, Inc.


The Pons

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The Pons

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The Cerebellum   Functions of the Cerebellum   Adjusts postural muscles   Fine-tunes conscious and subconscious movements

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The Cerebellum   Structures of the Cerebellum   Folia   Surface of cerebellum   Highly folded neural cortex

  Anterior and posterior lobes   Separated by primary fissure

  Cerebellar hemispheres:   Separated at midline by vermis

  Vermis   Narrow band of cortex

  Flocculonodular lobe   Below fourth ventricle Copyright © 2010 Pearson Education, Inc.


The Cerebellum   Structures of the Cerebellum   Purkinje cells   Large, branched cells   Found in cerebellar cortex   Receive input from up to 200,000 synapses

  Arbor vitae   Highly branched, internal white matter of cerebellum   Cerebellar nuclei: embedded in arbor vitae: –  relay information to Purkinje cells Copyright © 2010 Pearson Education, Inc.


The Cerebellum   Structures of the Cerebellum   The peduncles   Tracts link cerebellum with brain stem, cerebrum, and spinal cord: –  superior cerebellar peduncles –  middle cerebellar peduncles –  inferior cerebellar peduncles

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The Cerebellum   Disorders of the Cerebellum   Ataxia   Damage from trauma or stroke   Intoxication (temporary impairment)   Disturbs muscle coordination

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The Cerebellum

Figure 13–7a The Cerebellum. Copyright © 2010 Pearson Education, Inc.


The Cerebellum

Figure 13–7b The Cerebellum. Copyright © 2010 Pearson Education, Inc.


The Cerebellum

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The Mesencephalon   Structures of the Mesencephalon   Tectum   Two pairs of sensory nuclei (corpora quadrigemina): –  superior colliculus (visual) –  inferior colliculus (auditory)

  Tegmentum   Red nucleus (many blood vessels)   Substantia nigra (pigmented gray matter)

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The Mesencephalon   Structures of the Mesencephalon   Cerebral peduncles   Nerve fiber bundles on ventrolateral surfaces   Contain: –  descending fibers to cerebellum –  motor command fibers

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The Mesencephalon

Figure 13–8a The Mesencephalon. Copyright © 2010 Pearson Education, Inc.


The Mesencephalon

Figure 13–8b The Mesencephalon. Copyright © 2010 Pearson Education, Inc.


The Mesencephalon

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The Diencephalon   Integrates sensory information and motor commands   Thalamus, epithalamus, and hypothalamus   The pineal gland   Found in posterior epithalamus   Secretes hormone melatonin

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The Diencephalon   The Thalamus   Filters ascending sensory information for primary sensory cortex   Relays information between basal nuclei and cerebral cortex   The third ventricle   Separates left thalamus and right thalamus   Interthalamic adhesion (or intermediate mass): –  projection of gray matter –  extends into ventricle from each side Copyright © 2010 Pearson Education, Inc.


The Diencephalon   The Thalamus   Thalamic nuclei   Are rounded masses that form thalamus   Relay sensory information to basal nuclei and cerebral cortex

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The Diencephalon   Five Groups of Thalamic Nuclei   Anterior group   Anterior nuclei   Part of limbic system (emotions)

  Medial group   Provides awareness of emotional states

  Ventral group   Relays sensory information Copyright © 2010 Pearson Education, Inc.


The Diencephalon   Five Groups of Thalamic Nuclei   Posterior group   Pulvinar nucleus (sensory)   Lateral geniculate nucleus (visual)   Medial geniculate nucleus (auditory)

  Lateral group   Affects emotional states   Integrates sensory information Copyright © 2010 Pearson Education, Inc.


The Diencephalon

Figure 13–9 The Thalamus. Copyright © 2010 Pearson Education, Inc.


The Diencephalon

Figure 13–9a The Thalamus. Copyright © 2010 Pearson Education, Inc.


The Diencephalon

Figure 13–9b The Thalamus. Copyright © 2010 Pearson Education, Inc.


The Diencephalon

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The Diencephalon   The Hypothalamus   Mamillary bodies   Process olfactory and other sensory information   Control reflex eating movements

  Infundibulum   A narrow stalk   Connects hypothalamus to pituitary gland

  Tuberal area   Located between the infundibulum and mamillary bodies   Helps control pituitary gland function

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The Diencephalon

Figure 13–10a The Hypothalamus in Sagittal Section. Copyright © 2010 Pearson Education, Inc.


The Diencephalon

Figure 13–10b The Hypothalamus in Sagittal Section. Copyright © 2010 Pearson Education, Inc.


The Diencephalon   Eight Functions of the Hypothalamus   Provides subconscious control of skeletal muscle   Controls autonomic function   Coordinates activities of nervous and endocrine systems   Secretes hormones   Antidiuretic hormone (ADH) by supraoptic nucleus   Oxytocin (OT; OXT) by paraventricular nucleus

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The Diencephalon   Eight Functions of the Hypothalamus   Produces emotions and behavioral drives   The feeding center (hunger)   The thirst center (thirst)

  Coordinates voluntary and autonomic functions   Regulates body temperature   Preoptic area of hypothalamus

  Controls circadian rhythms (day–night cycles)   Suprachiasmatic nucleus Copyright © 2010 Pearson Education, Inc.


The Diencephalon

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The Limbic System   The Limbic System   Is a functional grouping that   Establishes emotional states   Links conscious functions of cerebral cortex with autonomic functions of brain stem   Facilitates memory storage and retrieval

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The Limbic System   Components of the Limbic System   Amygdaloid body   Acts as interface between the limbic system, the cerebrum, and various sensory systems

  Limbic lobe of cerebral hemisphere   Cingulate gyrus   Dentate gyrus   Parahippocampal gyrus   Hippocampus Copyright © 2010 Pearson Education, Inc.


The Limbic System   Components of the Limbic System   Fornix   Tract of white matter   Connects hippocampus with hypothalamus

  Anterior nucleus of the thalamus   Relays information from mamillary body to cingulate gyrus

  Reticular formation   Stimulation or inhibition affects emotions (rage, fear, pain, sexual arousal, pleasure) Copyright © 2010 Pearson Education, Inc.


The Limbic System

Figure 13–11a The Limbic System. Copyright © 2010 Pearson Education, Inc.


The Limbic System

Figure 13–11b The Limbic System. Copyright © 2010 Pearson Education, Inc.


The Limbic System

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The Cerebrum   The Cerebrum   Is the largest part of the brain   Controls all conscious thoughts and intellectual functions   Processes somatic sensory and motor information

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The Cerebrum   Gray matter   In cerebral cortex and basal nuclei

  White matter   Deep to basal cortex   Around basal nuclei

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The Cerebrum   Structures of the Cerebrum   Gyri of neural cortex   Increase surface area (number of cortical neurons)

  Insula (island) of cortex   Lies medial to lateral sulcus

  Longitudinal fissure   Separates cerebral hemispheres

  Lobes   Divisions of hemispheres Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Structures of the Cerebrum   Central sulcus divides   Anterior frontal lobe from posterior parietal lobe

  Lateral sulcus divides   Frontal lobe from temporal lobe

  Parieto-occipital sulcus divides   Parietal lobe from occipital lobe

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The Cerebrum

Figure 13–12a The Brain in Lateral View. Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–12b The Brain in Lateral View. Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–12c The Brain in Lateral View. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Three Functional Principles of the Cerebrum   Each cerebral hemisphere receives sensory information from, and sends motor commands to, the opposite side of the body   The two hemispheres have different functions, although their structures are alike   Correspondence between a specific function and a specific region of cerebral cortex is not precise Copyright © 2010 Pearson Education, Inc.


The Cerebrum   White Matter of the Cerebrum   Association fibers   Commissural fibers   Projection fibers

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The Cerebrum   White Matter of the Cerebrum   Association fibers   Connections within one hemisphere: –  arcuate fibers: »  are short fibers »  connect one gyrus to another

–  longitudinal fasciculi: »  are longer bundles »  connect frontal lobe to other lobes in same hemisphere

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The Cerebrum   White Matter of the Cerebrum   Commissural fibers  Bands of fibers connecting two hemispheres: – corpus callosum – anterior commissure

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The Cerebrum   White Matter of the Cerebrum   Projection fibers   Pass through diencephalon   Link cerebral cortex with: –  diencephalon, brain stem, cerebellum, and spinal cord

  Internal capsule: –  all ascending and descending projection fibers

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The Cerebrum

Figure 13–13a Fibers of the White Matter of the Cerebrum. Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–13b Fibers of the White Matter of the Cerebrum. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   The Basal Nuclei   Also called cerebral nuclei   Are masses of gray matter   Are embedded in white matter of cerebrum   Direct subconscious activities

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The Cerebrum   Structures of Basal Nuclei   Caudate nucleus   Curving, slender tail

  Lentiform nucleus   Globus pallidus   Putamen

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The Cerebrum

Figure 13–14a The Basal Nuclei. Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–14b The Basal Nuclei. Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–14c The Basal Nuclei. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Functions of Basal Nuclei   Involved with   The subconscious control of skeletal muscle tone   The coordination of learned movement patterns (walking, lifting)

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The Cerebrum   Motor and Sensory Areas of the Cortex   Central sulcus separates motor and sensory areas   Motor areas   Precentral gyrus of frontal lobe: –  directs voluntary movements

  Primary motor cortex: –  is the surface of precentral gyrus

  Pyramidal cells: –  are neurons of primary motor cortex Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Motor and Sensory Areas of the Cortex   Sensory areas   Postcentral gyrus of parietal lobe: –  receives somatic sensory information (touch, pressure, pain, vibration, taste, and temperature)

  Primary sensory cortex: –  surface of postcentral gyrus

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The Cerebrum   Special Sensory Cortexes   Visual cortex   Information from sight receptors

  Auditory cortex   Information from sound receptors

  Olfactory cortex   Information from odor receptors

  Gustatory cortex   Information from taste receptors Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–15a Motor and Sensory Regions of the Cerebral Cortex. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Association Areas   Sensory association areas   Monitor and interpret arriving information at sensory areas of cortex

  Somatic motor association area (premotor cortex)   Coordinates motor responses (learned movements)

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The Cerebrum   Sensory Association Areas   Somatic sensory association area   Interprets input to primary sensory cortex (e.g., recognizes and responds to touch)

  Visual association area   Interprets activity in visual cortex

  Auditory association area   Monitors auditory cortex

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The Cerebrum   Integrative Centers   Are located in lobes and cortical areas of both cerebral hemispheres   Receive information from association areas   Direct complex motor or analytical activities

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The Cerebrum   General Interpretive Area   Also called Wernicke area   Present in only one hemisphere   Receives information from all sensory association areas   Coordinates access to complex visual and auditory memories

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The Cerebrum   Other Integrative Areas   Speech center   Is associated with general interpretive area   Coordinates all vocalization functions

  Prefrontal cortex of frontal lobe   Integrates information from sensory association areas   Performs abstract intellectual activities (e.g., predicting consequences of actions) Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–15b Motor and Sensory Regions of the Cerebral Cortex. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Interpretive Areas of Cortex   Brodmann areas   Patterns of cellular organization in cerebral cortex

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The Cerebrum

Figure 13–15c Motor and Sensory Regions of the Cerebral Cortex. Copyright © 2010 Pearson Education, Inc.


The Cerebrum

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The Cerebrum   Hemispheric Lateralization   Functional differences between left and right hemispheres   Each cerebral hemisphere performs certain functions that are not ordinarily performed by the opposite hemisphere

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The Cerebrum   The Left Hemisphere   In most people, left brain (dominant hemisphere) controls   Reading, writing, and math   Decision making   Speech and language

  The Right Hemisphere   Right cerebral hemisphere relates to   Senses (touch, smell, sight, taste, feel)   Recognition (faces, voice inflections) Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–16 Hemispheric Lateralization. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Monitoring Brain Activity   Brain activity is assessed by an electroencephalogram (EEG)   Electrodes are placed on the skull   Patterns of electrical activity (brain waves) are printed out

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The Cerebrum   Four Categories of Brain Waves   Alpha waves   Found in healthy, awake adults at rest with eyes closed

  Beta waves   Higher frequency   Found in adults concentrating or mentally stressed

  Theta waves   Found in children   Found in intensely frustrated adults   May indicate brain disorder in adults

  Delta waves   During sleep   Found in awake adults with brain damage Copyright © 2010 Pearson Education, Inc.


The Cerebrum

Figure 13–17a-d Brain Waves. Copyright © 2010 Pearson Education, Inc.


The Cerebrum   Synchronization   A pacemaker mechanism   Synchronizes electrical activity between hemispheres

  Brain damage can cause desynchronization

  Seizure   Is a temporary cerebral disorder   Changes the electroencephalogram   Symptoms depend on regions affected Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   12 pairs connected to brain   Four Classifications of Cranial Nerves   Sensory nerves: carry somatic sensory information, including touch, pressure, vibration, temperature, and pain   Special sensory nerves: carry sensations such as smell, sight, hearing, balance   Motor nerves: axons of somatic motor neurons   Mixed nerves: mixture of motor and sensory fibers Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Cranial nerves are classified by primary functions   May also have important secondary functions   Distributing autonomic fibers to peripheral ganglia

  The 12 cranial nerve groups are identified by   Primary function   Origin   Pathway   Destination Copyright © 2010 Pearson Education, Inc.


Cranial Nerves

Figure 13–18 Origins of the Cranial Nerves. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Olfactory Nerves (I)   Primary function   Special sensory (smell)

  Origin   Receptors of olfactory epithelium

  Pathway   Olfactory foramina in cribriform plate of ethmoid

  Destination   Olfactory bulbs

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Cranial Nerves   Olfactory Nerve Structures   Olfactory bulbs   Located on either side of crista galli

  Olfactory tracts   Axons of postsynaptic neurons   Leading to cerebrum

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Cranial Nerves

Figure 13–19 The Olfactory Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Optic Nerves (II)   Primary function   Special sensory (vision)

  Origin   Retina of eye

  Pathway   Optic canals of sphenoid

  Destination   Diencephalon via optic chiasm

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Cranial Nerves   Optic Nerve Structures   Optic chiasm   Where sensory fibers converge   And cross to opposite side of brain

  Optic tracts   Reorganized axons   Leading to lateral geniculate nuclei

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Cranial Nerves

Figure 13–20 The Optic Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Oculomotor Nerves (III)   Primary function   Motor (eye movements)

  Origin   Mesencephalon

  Pathway   Superior orbital fissures of sphenoid

  Destination   Somatic motor: –  superior, inferior, and medial rectus muscles –  inferior oblique muscle –  levator palpebrae superioris muscle

  Visceral motor: –  intrinsic eye muscles Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Oculomotor Nerve Structures   Oculomotor nerve   Controls four of six eye-movement muscles   Delivers autonomic fibers to ciliary ganglion: –  ciliary ganglion: controls intrinsic muscles of iris and lens

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Cranial Nerves   The Trochlear Nerves (IV)   Primary function   Motor (eye movements)

  Origin   Mesencephalon

  Pathway   Superior orbital fissure of sphenoid

  Destination   Superior oblique muscle

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Cranial Nerves   The Abducens Nerves (VI)   Primary function   Motor (eye movements)

  Origin   Pons

  Pathway   Superior orbital fissures of sphenoid

  Destination   Lateral rectus muscle Copyright © 2010 Pearson Education, Inc.


Cranial Nerves

Figure 13–21 Cranial Nerves Controlling the Extra-Ocular Muscles. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Trigeminal Nerves (V)   Primary function   Mixed (sensory and motor) to face

  Origin   Ophthalmic branch (sensory): –  orbital structures –  nasal cavity –  skin of forehead, upper eyelid, and eyebrow –  part of nose

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Cranial Nerves   The Trigeminal Nerves (V)   Origin   Maxillary branch (sensory): –  lower eyelid –  upper lip, gums, and teeth –  cheek and nose –  palate and part of pharynx

  Mandibular branch (sensory): –  lower gums, teeth, and lips –  palate and part of tongue

  Mandibular branch (motor): –  motor nuclei of pons Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Trigeminal Nerves (V)   Pathway   Ophthalmic branch: –  superior orbital fissure

  Maxillary branch: –  foramen rotundum

  Mandibular branch: –  foramen ovale

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Cranial Nerves   The Trigeminal Nerves (V)   Destination   Sensory nerves: –  sensory nuclei in pons

  Motor nerves of mandibular branch: –  muscles of mastication

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Cranial Nerves   Trigeminal Nerve Structures   Trigeminal nerves   Largest cranial nerves   With three major branches

  Semilunar ganglion   Contains cell bodies of sensory neurons

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Cranial Nerves

Figure 13–22 The Trigeminal Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Facial Nerves (VII)   Primary function   Mixed (sensory and motor) to face

  Origin   Sensory: –  taste receptors on anterior 2/3 of tongue

  Motor: –  motor nuclei of pons

  Pathway   Internal acoustic meatus to facial canals (stylomastoid foramina) Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Facial Nerves (VII)   Destination   Sensory: –  sensory nuclei of pons

  Somatic motor: –  muscles of facial expression

  Visceral motor: –  tear and nasal mucous glands –  submandibular and sublingual salivary glands Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Facial Nerve Structures   Facial nerve branches   Temporal   Zygomatic   Buccal   Mandibular   Cervical branches

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Cranial Nerves   Facial Nerve Structures   Geniculate ganglia   Hold cell bodies of sensory neurons

  Pterygopalatine ganglia   Postganglionic fibers innervate glands (lacrimal, nasal cavity, and pharynx)

  Submandibular ganglia   Innervate salivary glands

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Cranial Nerves

Figure 13–23a The Facial Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves

Figure 13–23b The Facial Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Vestibulocochlear Nerves (VIII)   Primary function: special sensory   Vestibular branch: –  balance and equilibrium

  Cochlear branch: –  hearing

  Origin   Receptors of inner ear

  Pathway   Internal acoustic meatus of temporal bones

  Destination   Vestibular and cochlear nuclei of pons and medulla oblongata Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Vestibulocochlear Nerve Structures   Vestibular branch   Originates at receptors of vestibule (balance)   Connects to vestibular nuclei of pons and medulla oblongata

  Cochlear branch   Originates at sensors of cochlea (hearing)   Connects with cochlear nuclei of pons and medulla oblongata

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Cranial Nerves

Figure 13–24 The Vestibulocochlear Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Glossopharyngeal Nerves (IX)   Primary function   Mixed (sensory and motor) to head and neck

  Origins   Sensory: –  posterior 1/3 of tongue –  part of pharynx and palate –  carotid arteries

  Motor: –  motor nuclei of medulla oblongata Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Glossopharyngeal Nerves (IX)   Pathway   Jugular foramina between occipital and temporal bones

  Destination   Sensory: –  sensory nuclei of medulla oblongata

  Somatic motor: –  nerves involved in swallowing

  Visceral motor: –  parotid salivary gland Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Glossopharyngeal Nerve Structures   Superior and inferior ganglion   Sensory neurons of tongue and pharynx

  Otic ganglion   Synapse visceral motor fibers

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Cranial Nerves

Figure 13–25 The Glossopharyngeal Nerve. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Vagus Nerves (X)   Primary function   Mixed (sensory and motor)   Widely distributed in thorax and abdomen

  Origins   Sensory: –  part of pharynx –  auricle and external acoustic meatus –  diaphragm –  visceral organs of thoracic and abdominopelvic cavities

  Motor: –  motor nuclei in medulla oblongata Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Vagus Nerves (X)   Pathway   Jugular foramina   Between occipital and temporal bones

  Destination   Sensory: –  sensory nuclei and autonomic centers of medulla oblongata

  Visceral motor: –  muscles of the palate and pharynx –  muscles of the digestive, respiratory, and cardiovascular systems in thoracic and abdominal cavities Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Vagus Nerve Structures   Vagus nerves   Branch and radiate extensively

  Superior (jugular) ganglion and inferior (nodose) ganglion   Hold sensory neurons

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Cranial Nerves

Figure 13–26 The Vagus Nerve.

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Cranial Nerves

Figure 13–26 The Vagus Nerve.

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Cranial Nerves   The Accessory Nerves (XI)   Primary function   Motor to muscles of neck and upper back

  Origin   Motor nuclei of spinal cord and medulla oblongata

  Pathway   Jugular foramina between occipital and temporal bones

  Destination   Internal branch: –  voluntary muscles of palate, pharynx, and larynx

  External branch: –  sternocleidomastoid and trapezius muscles Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   Accessory Nerve Structures   Spinal root   Motor fibers that originate in anterior gray horns of first five cervical segments of spinal cord

  Cranial root   Motor fibers that originate in medulla oblongata

  Internal branch   Joins the vagus nerve

  External branch   Controls muscles of neck and back Copyright © 2010 Pearson Education, Inc.


Cranial Nerves   The Hypoglossal Nerves (XII)   Primary function   Motor (tongue movements)

  Origin   Motor nuclei of medulla oblongata

  Pathway   Hypoglossal canals of occipital bone

  Destination   Muscles of tongue Copyright © 2010 Pearson Education, Inc.


Cranial Nerves

Figure 13–27 The Accessory and Hypoglossal Nerves. Copyright © 2010 Pearson Education, Inc.


Cranial Nerves

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Cranial Nerves

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Cranial Reflexes   Cranial Reflexes   Monosynaptic and polysynaptic reflex arcs   Involve sensory and motor fibers of cranial nerves   Clinically useful to check cranial nerve or brain damage

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Cranial Reflexes

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