The Episcopal basilica at Stobi, the oldest and most important Early Christian monument in the Republic of Macedonia, is among the numerous treasures of great cultural and historical significance uncovered under the deep layers of earth deposited with centuries in the ancient town of Stobi. After almost a century of research, the Episcopal basilica still attracts the interest of those who study the remains of the Macedonian cultural past from various aspects. One of them, certainly, is the fresco paintings that decorated the interior of this Early Christian temple. Because of its state of preservation and its iconographical and coloristic qualities, the wall paintings from the Episcopal basilica represent a unique and exceptional example of painterly cultural heritage from the 4th century in the wider Mediterranean region.