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Contents Introduction Cellular Blood Brain Organs Disease Medicine Index Picture Credits
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Macrophage and platelets (coloured scanning electron micrograph) Platelets are fragments of white blood cells, and the two are the maintenance team of the blood supply. This image shows platelets (in purple) still attached to a macrophage white blood cell (pink). Macrophages clean the system by engulďŹ ng and destroying unwelcome pathogens, dead cells and other cellular debris. Platelets repair leaks in the system by clotting blood. Too few platelets can result in excessive bleeding; too many can lead to thrombosis, when a clot obstructs the blood supply. (MagniďŹ cation: x7000 at 10cm/4in size)
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Liver cells (coloured scanning electron micrograph) This image shows several specialized elements (organelles) within two liver cells (hepatocytes). Immediately above the nucleus (large yellow ovoid, lower left of centre), the wavy blue lines are folds of tissue producing proteins, steroids and other material. The blue lines on the right are the Golgi apparatus which prepares protein involved in secretion. Large pale yellow spots are fat droplets, smaller ones waste-digesting lysosomes. The green spots are mitochondria, which generate energy; the brown matter is energy-storing glycogen. (MagniďŹ cation: unknown)
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Kidney glomeruli (coloured scanning electron micrograph) Like a shrub in full bloom, flowers of blue glomeruli grace the orange stems of blood vessels in the human kidney. Glomeruli consist of a tight knot of blood capillaries covered in podocyte cells. Podocytes have footlike extensions which they wrap around the capillaries, leaving slits between them. The slits act as tiny filtration units to remove toxic waste products from the blood. The filtered fluid then drains to the bladder as urine. (Magnification: unknown)
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Bacteriophage (coloured transmission electron micrograph) Bacteriophages are viruses that infect bacteria; this one, a T4 bacteriophage (orange), has just injected its viral DNA into an E. coli bacterium (blue). It is anchored to the surface of the cell by spidery tail fibres. The tail contracts to allow a syringe-like tube below its base to puncture the cell membrane, emptying the DNA contents of the head into the bacterium. New T4 phages then grow, kill and depart from the host cell within 30 minutes. (Magnification: x65000 at 6x7cm/2¼x2¾in size)
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pub date februar y 2015 Take a fantastic journey through the human body, thanks to the magic of technology and the most spectacular microscopic images ever created. These pictures, as beautiful as any art, provide a window into the wonder of our brains, cells, hormones, even our diseases. Enjoy the collection purely as a visual voyage or as a means of understanding the science behind the images—which all include the scale of the photography as well as the scientific details in layman’s terms. • Review copy mailing to trade publications • Review copy mailing to art and science magazines and newspaper editors • Blogger outreach to art, science, and general interest websites/blogs • Goodreads promotion Colin Salter is the coauthor of Everything You Need to Know About Inventions (Thunder Bay Press). He is a history and science writer who has written about everything, including the private lives of marine gastropods. His contributions to Chambers’ Biographical Dictionary include the entries for 500 living scientists. For more information, contact Josh Redlich at (646) 688-2484 or jredlich@sterlingpublishing.com
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February 2015 Science & Nature / Science & Technology $35.00 ($39.50 Canada) Hardcover with Jacket 10 × 10 • 192 pages (all in color) 978-1-84994-192-1 To order book, scan here
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