MediWales Review - Summer 2009 by Teamworks

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MEDIWALES IS SUPPORTED BY THE WELSH ASSEMBLY GOVERNMENT

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medica special

Medica 18-21 November 2009 - Messe Düsseldorf, Germany

The Welsh Pavilion: Hall 16 Stand F30 This MediWales ‘Medica Special’ Review is your introduction to the thriving medical technology sector in Wales. It includes a directory of all of those companies on the International Business Wales Medica mission 2009, as well as a snapshot of some of the most exciting products and services being offered by Welsh companies in this sector. Medica is the largest and leading global exhibition for the medical sector. It runs alongside the leading international fair for medical manufacturing supplies, Compamed. Medica and Compamed together will occupy all 18 halls of the Düsseldorf Exhibition Centre and organisers expect more than 137,000 visitors from over 100 countries. Medica covers the entire range of outpatient and in-patient healthcare, including: electrical medicine/medical devices, laboratory technology/diagnostics, physiotherapy, orthopaedic technology, medical supplies (essential supplies and consumables), information and communication technology, textiles, medical furniture, furnishings, facility management, building services. At the same time, Compamed addresses all aspect of supplies to the medical manufacturing sector: raw materials, components, parts, packaging, services for use in medical device production. International Business Wales (IBW) is the Welsh Assembly Government’s international trade and investment arm, forming part of the Department of Innovation, Enterprise and Networks. It acts as the driving force in establishing

alliances between companies in Wales and their counterparts overseas. At the same time IBW actively seeks out inward investment opportunities for client companies looking to Europe and the UK as a preferred international business location. The Welsh Assembly Government is a democratically elected body, which was established in May 1999. It has devolved powers and responsibilities for developing and implementing policies in Wales on a broad range of issues, including economic development, education, the environment, agriculture, housing, roads and transport. The Welsh Assembly Government works closely with primary legislation and has powers to introduce secondary legislation of its own. MediWales has been active for over seventeen years and is the representative body for the medical sector in Wales. Supported by the Welsh Assembly Government, MediWales is owned by its members and led by directors drawn from senior industrialists and academics in Wales. MediWales generates a unique environment for networking, collaboration and communication between industry, higher education and health service members. This is delivered through an active schedule of seminar events and publications, supported by the MediWales website and maintained via constant communication with members and stakeholders. From this pivotal role, MediWales is able to represent both its members and the wider sector to governmental and international partners.

Contents Paths out of recession Wales Pavilion Directory

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Boots Centre for Innovation

DTR

GX Group

PDR

M E M B E R

7 Schooner Way, Atlantic Wharf, Cardiff CF10 4DZ Telephone: +44 (0)29 2047 3456 Forum Manager: gwyn.tudor@mediwales.com Project Manager: debbie.laubach@mediwales.com Project Coordinator: jess.fisher@mediwales.com (Contact for editorial and advertising) Web:

MediWales is a founder member of Medilink UK, the network of regional medical technology organisations that represents the interests of around 3000 organisations across the UK.

www.mediwales.com

MediWales Chairman: Mr Greg Baily, Huntleigh The MediWales Medica Special is designed by Teamworks Design Consultants

WALES

medica special

Paths out of recession by Jess Fisher

Last year’s Review of the Welsh Bioscience sector highlighted an era of mergers and acquisitions for Indigenous Welsh Companies. A year later – and over a year into the global recession – the Review tells a different narrative, one that illustrates the growth in significance for Welsh Bioscience and Medical Technology companies as they attempt to keep the credit-crunch at bay. In March of this year, the Welsh Assembly Government commissioned MediWales – Wales’s Medical Technology and Bioscience forum – to ‘map’ the Welsh Bioscience sector. This project resulted in key findings: there are 322 companies in Wales defined as ‘Bioscience’; the sector employs more than 15,000 people; and contributes more than £1.3 billion to the Welsh economy. Key opinion leaders knew Bioscience in Wales was strong, but these figures substantiate its value, emphasising the sector’s worth as a field for future investment.

The sector’s segmentation by activity provides further insight into Wales’s strengths, but also highlights how international trade shows like Medica are vital to the growth and success of the sector. 63% of companies operating under the umbrella of Bioscience are Medical Technology companies. With this many businesses producing innovative medical devices, in a sector characterised by its global markets, the potential for international trade is huge. Already statistics for the first quarter of 2009 showed that Welsh healthcare exports grew by 9.3%, seeing a rise from £187m to £205m. These indicators suggest that Welsh Medical Technology companies are more than able to trade themselves out of the recession. Adding to this argument, when MediWales Members were asked what their priorities were in this difficult economic climate, surprisingly, they were not funding or investment capital. Though obviously significant, most of our companies said that if MediWales can create opportunities for its members to do business, then sustainability and growth would follow. MediWales has collected evidence indicating that access to clinical expertise and facilities for product evaluations and trials is a critical success factor for its membership. In a survey of the current situation, MediWales requested case studies of companies’ successes in procurement and/or any problems experienced. The resounding reply was that the most significant issue facing our companies is access to clinical expertise throughout the product development process and if this could be improved, then companies could resist difficult financial times. These messages led to the MediWales ‘Clinical Access’ initiative: a working group that has brought together key players and opinion leaders from academia, business and clinical institutions across Wales in order to discuss and implement necessary change. This

vibrant interdisciplinary initiative, supported and observed by the Welsh Assembly Government, has been discussing the following areas: early stage evaluation of ideas; needs assessment; evidence gathering (not always formal clinical trials); product assessment by the UK National Health Service; and procurement. The group is working hard to improve access in all of these areas. Early talks have resulted in progress on establishing the evidence required by procurement and some Welsh companies have succeeded in getting products closer to market, such as DTR Medical, Convatec, and Invacare. Other outputs include the proposed development of a

£1.3 billion to the Welsh economy ‘clinical access route map’: this will not only layout clear pathways for healthcare companies to follow across the five identified stages, but it will detail who to communicate with in Wales and how to proceed. The fact that this working group was able to materialise at all highlights another of Wales’s strengths. Key opinion leaders in the Welsh Assembly Government, clinicians (including consultants, procurement nurses and clinical researchers), clinical academics, and industry are able to meet and discuss important issues that affect the sector. The ease with which this occurred could be down to good communication networks, however it is also likely to be a result of a devolved health service and a relatively small nation, which makes high level access across interest groups that much easier. Whatever the reason, meetings like this show that Wales is able to communicate with little bureaucracy and create working partnerships harder to achieve in the wider UK. As a result, Wales has a unique opportunity

to create successful clinical pathways and systems of its own if it takes advantage of the benefits size and devolution brings. A re-occurring annual Welsh highlight is the BioWales conference, tradeshow and brokerage event – one of the UK’s largest Bioscience conferences and bio-partnering events. Now in its eighth year, BioWales has become a landmark event, attracting delegates from throughout the UK and Europe. The success of Bioscience relies on successful connections and collaborations between its institutions. BioWales promotes and provides a platform for vital networking year after year, offering continuity and the right environment - a major factor in its popularity. Next year the conference takes place between 17-18 March, at the Vale Hotel near Cardiff. The bio-partnering event specifically encourages international collaborations between the UK and Europe through its one-to-one meetings. The people interested in brokerage meetings are linked up by the Enterprise Europe Network (EEN), which brings together those seeking and those offering technology opportunities as well as supporting access to European-wide research funding frameworks. The activity from BioWales feeds into EEN activities that the Welsh Assembly Government’s Department for Economy and Transport facilitates throughout the year, which often leads to

322 Bioscience companies international partnerships and inward investment. Like the Welsh Bioscience sector, the event has grown substantially since inception: last year it attracted over 400 delegates with more than 40 exhibitors. Next year’s conference is themed around regenerative medicine; stem-

cell industrialisation; point-of-care diagnostics; cancer genetics; and translational research, reflecting the current academic and industrial excellence in both Wales and UK-wide.

15,000 employees Eminent speakers from both industry and academia will describe some of the recent developments in these areas, helping to map future trends in the Bioscience landscape. Underpinning the success of strong networks and collaboration, Wales has a vibrant manufacturing base; a large number of innovative medical device companies; world-renowned academic institutions; and academic and clinical centres of excellence. These strengths, combined with the effects of the sector mapping project, the clinical access initiative and a strong programme of regular events, has made Wales and the sector an exciting and vibrant environment to work in. Confident and self aware of its own strengths, there is an understanding of how things currently stand, which helps to set goals and targets for the future. Bioscience’s successes have been highlighted, but the sector is also honest about where it needs to improve. The deep-routed networks and willingness by key players to implement change and be involved show that the sector - and indeed Wales - is proactive, not just reactive to problems. As Wales takes advantage of its skills and opportunities, there will be a multiple pay-off: enormous potential for improved healthcare, reduced costs, economic benefits, and increased inward investment. The unique and sustained identity of Wales as a small, but clever devolved nation, places the country in a position to push Bioscience as Wales’s strongest sector.

Need an injection of Innovation?

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BIC Innovation & Pera Cymru Pencoed Technology Centre, Bridgend CF35 5HZ

T: 01656 861536 1 Llys Onnen, Parc Menai, Bangor LL57 4DF

T: 01248 671101 Contact: Huw Watkins 07816 650974 / huw.watkins@bic-innovation.com Rod Howells 07920 563576 / rod.howells@pera.com

NEW in 2009 Pera Cymru is a partnership between BIC Innovation & Pera, Europe’s leading innovation and performance improvement organisation.

www.bic-innovation.com B I C

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WALES PAVILION DIRECTORY International Business Wales

Helen Griffiths Regional Manager - Europe

Welsh Assembly Government Department for the Economy and Transport, Plas Glyndwr, Kingsway Cardiff CF10 3AH Tel: +44 29 2082 8788 Fax: +44 2044 2696 Email: helen.marie.griffiths@wales.gsi.gov.uk Web: www.ibwales.com

International Business Wales (IBW) is the Welsh Assembly Government’s international trade and investment arm. It forms part of the Department for the Economy and Transport, and acts as the driving force in establishing alliances between companies in Wales and their counterparts overseas, whilst actively seeking out inward investment opportunities for client companies looking to Europe and the UK as a preferred international business location.

Head Office Unit 2 Coed y Parc Industrial Estate Bethesda Gwynedd LL57 4YY UK Tel: +44 (0) 1248 600666

Blizzard Protection Systems manufacture the thermally resistant material Reflexcell™. Recent winner of the Queen’s Award for Enterprise: Innovation, Reflexcell™ is a triple layered metallised polymer foil which expands to form insulating air pockets as well reflecting heat. It is lightweight and has excellent insulating properties. Blizzard Protection Systems use the material to manufacture their Blizzard Survival range of products including jackets, blankets and sleeping bags and also to manufacture the self heating product Blizzard Heat. Blizzard products are used in the treatment of hypothermia, shock, injury and other extreme outdoor situations. Blizzard distribute in over 30 different countries worldwide, to 7 key market sectors; Military – medical and infantry; Medical – civilian; Emergency Services – Ambulance, Police, Fire service etc; Search & Rescue; Emergency Preparedness; Outdoor retail; Disaster Relief and Corporate Healthcare Our trip to Medica will help us to reinforce our position with existing customers and we also hope to attract new customers and to expand our worldwide distributor network.

Institute of Life Science, University of Swansea, Swansea, SA2 8PP Wales, UK Tel: + 44 (0) 1792 513 722 Email: info@bootsinnovation.co.uk Web: www.bootsinnovation.com

The Boots Centre for Innovation seeks out innovative health and beauty products at any stage - from concept to shelf-ready - for Alliance Boots pharmacy-led stores worldwide. It offers entrepreneurs an array of support services essential to the commercialisation of their ideas. Embracing the principles of Open Innovation, the Centre compliments the established product development resources of Alliance Boots. Sitting at the centre of a dynamic knowledge network, the Boots Centre for Innovation also identifies and evaluates key trends and emerging opportunities in the health and beauty markets and helps bring together expertise from industry, academia and the professions to define the future direction of those markets. Objectives at Medica: Seek out innovative consumer healthcare products and services which are suitable for Boots stores in the UK and throughout the global Boots distribution network. Identify opportunities that could meet our customers’ unmet healthcare needs.

Helen is responsible for developing trade for Welsh companies within Europe. In doing so, she manages a network of business consultants based throughout the Region and leads a number of business delegations from Wales to key European markets and trade shows.

Blizzard Protection Systems

Contract electronics manufacturing excellence

35 years, world class engineering experience World leading manufacturing facilities 10,000 Sq meters – factory space 3 million shots per day auto mount facility First class worldwide distribution network 9,000 Sq meters –Warehousing space Extensive Product approval and testing facilities

Jill Taylor Sales Manager

6,000 Sq meters – Office space On-site customer service call centre

Boots Centre for Innovation

Service repair solutions The Complete Business solution

Sony UK Technology Centre Pencoed Technology Park • Pencoed Mid Glamorgan • CF35 5HZ Tel 00 44 1656 860666 • Fax 00 44 1656 863906 Uktec.enquires@eu.sony.com • www.sonyuktec.co.uk

Gail Easthaugh

James Ellis

WALES

medica special

WALES PAVILION DIRECTORY Chromogenex Technologies

Cardiff Medicentre Heath Park Cardiff CF14 4UJ South Wales United Kingdom Tel: (029) 2075 7744 Fax: (029) 2075 0239 Email: enquiries@cardiffmedicentre.co.uk Web: www.cardiffmedicentre.co.uk

Jeremy Jones

The Cardiff Medicentre is Cardiff’s premier home for medical innovation businesses in Cardiff. The Centre was the first of its kind in the United Kingdom and offers an attractive environment for new and developing medical and pharmaceutical based enterprises. The Centre is located on the University Hospital of Wales campus which extends across 53 acres and provides a working base for over 4,000 people. In addition, the campus is also home to Cardiff University Medical School. Becoming a tenant at the Medicentre will enable your company to bring the innovative and practical application of medical or bioscience research efficiently to the marketplace. The Cardiff Medicentre is therefore the ideal place to develop your medical, bioscience or life sciences technology based business, offering: Encouragement for business growth; competitive rents and flexible terms; a prestigious location; close links with Cardiff University & the local NHS Trust; access to focused business support packages; and a strong cluster of medical technology businesses

Peter McGuinness, Managing Director

Paul Webber, Director

CellNass is the innovative archive management service arm of CellPath Ltd. For the past 40 years Cellpath has been supplying consumables for human tissue sampling to Histology and Cytology departments at hospitals and laboratories (see www.cellpath.co.uk); from this initial core activity the company has branched out into material archiving, a logical development into the field of services. Cellnass offers the first dedicated Human Tissue Association (HTA) licensed offsite storage facility for archiving pathology samples in the UK, which is used by well-known private and public hospitals, pathology laboratories and universities. It has a strong team of professionals bringing together extensive expertise in Pathology and logistics, and has the resources and ability to transport and archive large volumes of material safely and without inconvenience to hospital staff. Since inception there has been a rapid increase in the number of establishments using the facility and there are current plans to expand available storage.

Philip Webber, Managing Director Brian Reid, Export Sales Manager

CellPath feel that there is a lot of potential for expansion in European markets, and has appointed a Business Development Manager to seek out new opportunities, primarily in the near European countries where a detailed analysis of the markets has already been undertaken in-house. There is a real belief within CellPath that there is ‘untapped’ potential, particularly in the eastern European countries: the company would like to use Medica to help find a business partner in Europe. Cellpath has established itself as a dynamic innovative company, and has anenviable reputation over 25 years for reliability and customer service in its role as market leading supplier of cellular pathology consumables. In addition to supplying a comprehensive range of pathology consumables, Cellpath continues to be at the fore-front of the design and development of new products. Cellpath has the resources to offer contract manufacturing, processing and packaging, as well as warehouse and distribution for customers looking to outsource these labour-intensive operations. Objectives at Medica: Increase export market by meeting potential and existing suppliers, distributors and customers

17 Clarion Court Enterprise Park Swansea SA6 8RF Tel: +44 1792 797910 Fax: +44 1792 797955 Email: adavidson@dtrmedical.com Web: www.dtrmedical.com

DTR Medical provides medical professionals with high quality single-use sterile disposables that deliver patient and clinical value combined with exceptional levels of service. The company has operated for four years, during which time it won over 400 UK & International customers and has expanded the product range dramatically to meet new market demands. The range includes many new sterile single-use surgical instruments for specialities including ENT, neurosurgery, vascular and general surgery, and gynaecological procedures. In addition, the company supplies a range of products for sterile services including sterile precut silicone tubing. Objectives at Medica: Recruit new international distributors to sell our new product range worldwide; meet existing distributors and suppliers; and look for new products

19 White Swan Court Monmouth Monmouthshire NP25 3NY Tel: +44 [0]1600 714856 Email: Lyndon@E2L.uk.com webs: www.E2L.uk.com www.megabee.co.uk www.FAB.uk.com

Services - E2L is a design consultancy specialising in medical devices. Established for over 10 years and recognised as ‘Ambassadors for Innovation’ they offer a complete design package taking products from initial concept through to manufacture. Clients range from individuals with the ‘big idea’ through to multinationals and public sector bodies such as the National Health Service. Joint collaborative ventures or contract design work is undertaken, as well as developing their own products. Products – Two products are going to Medica: ‘MegaBee‘’ (www.megabee.net) a frequent-use communicator for people who cannot speak or write legibly, for MND, MS, locked-in syndrome, and similar disabilities. ‘FAB‘’ Frenchay Alphabet Board (www.FAB.uk.com), a low technology, anti-microbial, finger pointing chart for non-vocal users who have tremors. These are for a similar client group but include Parkinsons’ Disease sufferers. Objectives at Medica: Medica is an opportunity to identify new distributors, collaborative design clients, and to introduce out latest innovations.

DTR Medical

Andrew Davidson, Managing Director E2L Products

Cellpath 80 Mochdre Enterprise Park Newtown, Powys SY16 4LE Tel: 01686 611333 Fax: 01686 622946 Email: Philip@cellpath.co.uk Web: www.cellpath.co.uk

Chromogenex design, manufacture and service lasers and intense light systems for the health and beauty market. Key products are: ilipo - a body shaping fat reducing device without the need for pain, needles or downtime. Chromolite/Phaser – intense pulse light (ipl) for hair removal, skin rejuvenation and pigmentation. Regenlite – a pulse dye laser for vascular, acne and skin pigmentation. The company also sells consumables, service contracts and other ancillary goods. The company has established direct sales operations in the UK, French and Canadian markets and makes further export sales via a comprehensive network of distributors.

Kevin Williams, Sales Director

CellNass Europe 80 Mochdre Enterprise Park Newtown Powys SY16 4LE Tel: +44 (0)1686 611333 Fax: +44 (0) 1686 622946 Web: www.cellnass.com

Units 1&2 Heol Rhosyn Dafen Park Llanelli SA14 8QG Tel: 01554 755444 Fax: 01554 755444 kwilliams@chromogenex.com www.chromogenex.com

Lyndon Owen, Managing Director

WALES

medica special

WALES PAVILION DIRECTORY Firefly Medical

HSBC Bank Plc Unit B, Cwm Cynon Business Park, Mountain Ash, CF45 4ER. Tel: 01443 475539 Fax: 01443 473379. www.fireflymedical.co.uk

Ian Mortimer, General Manager

Firefly Medical Ltd was established to develop leading medical products for the NHS and primary care fields. Augmented with selective sales of leading equipment, consumables and pharmaceuticals. We have a experienced external sales team with strengths in occupational health, primary care and sexual health. We will shortly develop our website further to actively promote a broad product range. We are ISO13485:2003 accredited and have a pharmaceutical wholesale dealers license. We design and manufacture medical products. We have recently launched our own design and manufactured Sterile Vaginal Speculum which is the leading product in the market. Having recently been accepted on the framework agreement for the NHS, we are now looking to export throughout Europe and Middle East. Objectives at Medica: We are now looking for distribution partners across Europe for the PuraspecTM; we have identified a number of distributors and are looking for more. We are also interested in potential partner distribution of own branded products within the U.K.

97 Bute Street Cardiff CF10 5NA edward.white@hsbc.com www.hsbc.co.uk

Edward White, Regional International Commercial Manager

Home Telehealth

GX Group The Mayfield Usk, Monmouthshire, Wales NP15 1SY United Kingdom Tel: +44 1291 673437 Fax: +44 1291 673438 Email: claire@gxl.co.uk Web: www.gxl.co.uk

Claire Banks Business Development Manager

GX is a leading independent design consultancy. We have a proven tract record in high quality design, development and manufacture of instruments, machines and products for the medical sector. Recent clients include: Bayer Diagnostics, Gyrus Medical, Rhytec, CLP, Pall, Medical Support Systems, Morecare and British Gas. GX’s committed and experienced workforce combine technical excellence and design innovation to meet clients’ needs. Key areas of expertise, all available in-house, include: Industrial design, Mechanical engineering, Electronic design, Rapid prototyping, Optronics design, Software design, CAD animations GX Systems is a leading independent systems integrator. We have a proven track record in the high quality provision of automation and control systems. We have the skills to provide a complete Turnkey Solution including Hardware, Control and project management to bring your project in on time. Recent clients include: British Airways, Celsa UK, BAAE, Serco, Falkirk CC and Cardiff University. Key areas of expertise, all available in-house, include: Vehicle location systems, Mobile workflow systems, Asset Management, PLC’s systems, SCADA systems, MES Systems, Instrument and Control panel build, After sales support

HSBC Holdings plc serves over 130 million customers worldwide through 9,500 offices in 86 countries and territories in Europe, the Asia-Pacific region, the Americas, the Middle East and Africa. With assets of some US$2,527 billion at 31 December 2008, HSBC is one of the world’s largest banking and financial services organisations. HSBC is marketed worldwide as ‘The world’s local bank’. HSBC has over 8,000 Relationship Managers operating globally, with over 1,600 in the UK dedicated to helping businesses maximize their potential. HSBC has over 200 international product specialists in the UK helping SMEs with importing and exporting. HSBC has over 55 Multi-lingual International Banking Centres worldwide which specialise in opening accounts in overseas markets to help businesses make the transition. HSBC are attending Medica 2009 to further it’s links with International Business Wales in Germany and mainland Europe, and build relationships with businesses from Wales benefiting from global opportunities.

Saint Line House Mount Stuart Square Cardiff CF10 5LR Tel: 029 2044 4795 Fax: 029 2044 4778 E-mail: peterbw@hometelehealthltd.co.uk Web: www.hometelehealthltd.co.uk

HTL is a provider of Telehealth Managed Services dedicated to bringing innovation to Health, Social Care Providers, Industry and Consumers. HTL’s objective is to leverage its experience of working within both the public and private Healthcare markets on the delivery of new value-added services and solutions that deliver new applications generating improved clinical, operational and financial outcomes for our clients. The HTL portfolio of services, products and solutions extends across many segments of Health and Social Care including Health and Wellbeing, Chronic Disease Management, Telehealth, Telemedicine, Telecare, Assistive Technologies, eHealth grouped into three segments: technology solutions, managed services, programme implementation.

Spring Gardens Whitland Carmarthenshire SA34 0HR Tel: +44 (0) 1994 240798 Fax: +44 (0) 1994 240061 Email: andrew.thomas@magstim.com

Magstim provides the means for neuroscientists to work with the human brain in awake subjects by manufacturing and supplying state-of-the-art clinical and research instruments. Magstim and Neurosign products cover the fields of Neurology, Neurophysiology, Psychiatry, Cognitive Neuroscience as well as ENT, Orthopaedic and Neuro-surgery. Magstim maintains a strong commitment to R&D and product improvement. Collaborating with researchers in British and European major centres of expertise (as well as those in North America and Japan) ensures that Magstim remains informed about clinical and medical advances, enabling the company to develop products at the forefront of technology. Products are sold directly to hospitals and clinics in the UK and Ireland and exports account for much of the Magstim business. Our principal markets are in Germany, France, Benelux, Japan, the Far East and the USA. Magstim enjoys a close and effective relationship with its specialist distributors and provides significant training and after sales service.

Peter Brooke-Wavell

Magstim Company

Andrew Thomas, Marketing Manager John Scandone, International Sales Manager

WALES

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WALES PAVILION DIRECTORY PDR

MediWales 5-7 Schooner Way Atlantic Wharf Cardiff CF10 4DZ Tel/Fax: 029 2047 3456 Email: debbie.laubach@mediwales.com gwyn.tudor@mediwales.com Web: www.mediwales.com

Gwyn Tudor, Forum Manager

Debbie Laubach, Project Manager

MediWales has been active for over seventeen years and is the representative body for the health technology sector in Wales. With over 120 subscribed members, we are in regular communication with over 1,500 contacts. Supported by the Welsh Assembly Government, MediWales is owned by its members and led by directors drawn from senior industrialists and academics in Wales. MediWales generates a unique environment for networking, collaboration and communication between industry, higher education and health service members. This is delivered through an active schedule of seminar events and publications, supported by the MediWales website and maintained via constant communication with members and stakeholders. From this pivotal role, MediWales is able to represent both its members and the wider sector to governmental and international partners. Objectives at Medica: Debbie will be available on the Welsh stand to find out more about your business and promote the interest of our members and the sector.

Western Avenue Cardiff CF5 2YB T: 02920 416725 F: 02920 416973 E: jwevans@pdronline.co.uk W: www.pdronline.co.uk

PDR is one of Europe’s leading product development consultancies and research centre’s. It offers services of innovation, design and engineering development, prototyping, low volume manufacture and offshore manufacturing support. With over 15 years of experience PDR has developed a reputation for excellence in medical device development. With a collection of over 10 international design awards in the last three years alone PDR has a proven and reliable record of delivery. We consistently create successful products, and solutions for companies and organizations from around the world and across many markets. Our client base encompasses new start-up ventures to large multinationals to which we provide the unique combination of leading edge research with world class creativity, experience and application. PDR’s core efforts focus on the rapid design development of new medical products to the market place. Combining the user-insight with creative skill and engineering expertise to produce reliable, highly successful and market changing solutions. Objectives at Medica: To strengthen new client relationships and opportunities; to showcase our success in new product development.

Regus Cardiff City Haywood House North Dumfries Place Cardiff,CF10 3GA Tel: +44-(0)29-20647384 Fax: +44-(0)29-20646101 Mobile: 07517690898 E-mail: isabella.li@c-thme.com Head office website: www.c-thme.com

Tianhai UK Ltd, located in Cardiff, is an European subsidiary of ChongQing TianHai Medical Equipment Co., Ltd, which is a Hi-tech company established in 1995 specialized in R&D , manufacturing, sales and marketing, and after sales service of medical equipments used in Hospitals, Clinical Laboratories, Research Institutes. Three Main Technology Lines: 1)Clinical Inspection Analysis & Diagnostic Technology —Urinalysis, Blood Analysis, Medical Image Analysis, Traditional Chinese Medical Diagnosis 2)Blood Purification Technology —Hemodialysis Machine, Multifunctional Pump 3)LED-based Medical Illumination Technology —LED Medical Illumination Products Tianhai UK Ltd is at its early stage aiming: —To strengthen the cooperation with ENFIS. To promote medical equipment in UK market. To meet with potential distribution partners. To meet with possible new clients and associates. To seek more partners in the sustainable energy.

Eastgate Business Park Wentlog Avenue Cardiff CF3 2EY Tel: +44 (0) 845 330 4236 Fax: +44(0) 845 330 4231 Email: admin@ultrawave.co.uk Web: www.ultrawave.co.uk

Ultrawave have been manufacturing precision ultrasonic cleaning equipment for over 15 years for a wide range of industries and applications. In this time, Ultrawave have developed a range of cleaners for healthcare and medical environments including hospitals, sterile service departments and primary care facilities as well as by medical device manufacturers and pharmaceutical companies. The Hygea™ range of ultrasonic cleaning baths address modern standards of decontamination and incorporate a locking lid and integral printer for cycle traceability and validation. The Q-Series benchtop ultrasonic baths deliver improved cleaning through Frequency Leap technology and allow digital cycle traceability through an SD card port. In addition, Ultrawave can offer a range of tailored options, including hollow lumen instrument cleaners and ultrasonic tanks which can be inserted into wet benches. Ultrawave’s precision ultrasonic cleaning equipment is also used in the medical device and pharmaceutical manufacturing industry.

Jarred Evans, Commercial Director

Nightingale Care Beds Unit 20, Abenbury Way Wrexham Industrial Estate Wrexham LL13 9UZ Tel: 01987 661 999 Fax@ 01987 661 705 Web: www.nightingalebeds.co.uk Email: info@nightingalebeds.co.uk

Stuart Reid, Business Development Manager

Nightingale Care Beds Ltd is based in Wrexham, North Wales and is a manufacturer and supplier, for sale and hire, of a range of bariatric products designed to suit the larger patient. Nightingale supplies into the NHS (primary, secondary and acute), community, private health care suppliers as well as private individuals and is an approved supplier on the NHS supply chain framework agreement for beds and pressure area care products. Nightingale services are based around its core product the ProAxisplus bariatric bed with in built pressure area care system. The remainder of our products are designed to support the needs of the patient and their carers. We base our designs on ergonomic data supported by consultation with experts in manual handling, infection control and tissue viability plus patient feedback. Objectives at Medica: At Medica, Nightingale is seeking equipments that may compliment our current product range and to identify businesses where we may be able to develop mutually beneficial business links.

Tianhai UK

Chen Jun, Manager of International Trade Chongqing Tianhai Medical Equipment Company Ltd Long Haiying, Managing Assistant of International Trade - Chongqing Tianhai Medical Equipment Company Ltd

Oncomorph Analysis Aberystwyth University Commercialisation & Consultancy Services Visualisation Centre Penglais Aberystwyth SY23 3BF T: 020 7812 7366 M: 07967 086592 E: mfisher@exomedica.com Web: www.oncomorph.com

Dr Mark Fisher, CEO

Oncomorph Analysis, a spin out company from Aberystwyth University, was founded in 2008 to develop the use of existing MRI data with new image analysis software to improve the diagnosis and staging of prostate cancer. The company is developing a suite of software tools, including annotation and segmentation functions, for both external and internal tissue identification and a 3D registration tool, to yield tissue volumetric data. The core technology that enables Oncomorph Analysis to interrogate digital images is a shape/texture-based segmentation tool that can differentiate between the patterns of a tissue through the analysis of a small number of the total pixels that make up the larger image area. This reduces the amount of data that needs to be ‘crunched’ and speeds up the whole process of analysis. Objectives at Medica: The aim of going to Medica is to establish links with existing image technology businesses to broker joint venture opportunities to accelerate the route to market.

Ultrawave

Chris Czyrko, Sales and Marketing Manager

Lee Watkins, Healthcare Sales Manager

WALES

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Wentwood Medical

Unit 10 Distribution Unit 10 Distribution Ltd

Paul Mayberry, Managing Director

175-177 High Street Blackwood Gwent NP12 1AA UK Tel: 01495 228040 Mobile: 07790906168

Unit 10 Distribution Ltd is a collector of UK ethical drugs. The company takes advantage of the strict stock quotas imposed by manufacutures, the price descrepancies of drugs between European counties and the exchange rate. Drugs are sourced from a group of independantly owned retail pharmacies in South Wales. They are consolidated centrally and distributed to customers using state of the art robotic technology. Unit 10 Distribution currently exports over £20 million pounds annually of branded pharmaceuticals to Europe (mostly to Germany and Scandinavia), through UK based third parties. Unit 10 Distribution would now like to export directly to Europe, and is currently looking for strategic partners in Germany in order to do this.

200 Western Avenue Cardiff CF5 2YB T: +44 (0)2920 417 052 E: uwicresearch@daleharper.co.uk W: http://www.uwic.ac.uk/research/

The University of Wales Institute, Cardiff (UWIC) engages in research that is at the interface of new knowledge creation and its application. The research, therefore, has direct application in business, industry, the professions and the community at large. The University of Wales Institute, Cardiff (UWIC) has a long track record in applied research supported by a strong base of expertise and advanced scholarship. For the prospective student, this translates to an exciting and varied programme of postgraduate study ranging from art and design, education and health sciences to critical management, sport and tourism. For business partners and collaborators, we offer a portfolio of services that includes research and development, consultancy, and training to help enhance performance, improve competitiveness and develop the skills base. Dale Harper will be representing UWIC R&D and will be happy to assist you, whether your needs are for basic advice, research, consultancy, education or training.

The Manse Tabernacle Lane Llanvaches Monmnouthshire NP26 3BL Tel: + 44 (0) 7748 637400 E mail: scottforde@wentwoodmedical.com

Scott Forde, Managing Director

UWIC Research

Dale Harper (MSc) University of Wales Institute Cardiff (UWIC)

Zoobiotic

Dunraven Business Park Coychurch Road Bridgend CF31 3BG Tel: 0845 2301810 Fax: 01656 668047 Website: www.zoobiotic.com

Welsh Wound Network Would Healing Research Unit (WHRU) School of Medicine Cardiff University Heath Park Cardiff CF14 4XN Tel: 029 2074 2323 Email: clarkm@cardiff.ac.uk

Dr Michael Clark, Senior Research Fellow

The Welsh Wound Network is a new collaborative organisation dedicated to improving the clinical care of people with wounds in Wales. The network brings together the wealth of academic, clinical and commercial expertise in wound healing in Wales to facilitate the development of new practices and innovations by undertaking high quality collaborative research, audit and other enquiries. There are several well known and internationally respected research and clinical groups located in Wales including the Wound Healing Research Unit, the Surgical Materials Testing Laboratory, the All-Wales Tissue Viability Nurse Forum among several others. In this new venture all of these well established groups have come together to explore areas where collaboration would lead to enhancements in research, practice and commercial innovation. This ongoing communication is supported by a roster of conferences and other networking events throughout the year.

Wentwood Medical Ltd provides sales and marketing expertise to the biotechnology and pharmaceutical sectors in the UK and Europe. Our services include: • Strategic brand planning services, strategic marketing formulation and plan development. Integrated customer plan development, customer targeting strategy development, strategy implementation, operational brand management services and brand enhancement programmes. • Pre-launch activities (market assessment, market shaping), brand support programmes, patient programmes and aligning to NHS customers. • Marketing material production, web site design, customer, key opinion leader management and development. NHS funding expertise, NHS liaison, PCT contact • Communication with policy, formulary, funding & commissioning decision makers and Government lobbying. Sales targeting strategies and sales force re-design • Alliance management - co-promotional activities, start up company Sales, marketing and business development support Objectives at Medica: To make contact with pharmaceutical/healthcare companies who: Have a product or technology looking for entry to the UK market; are looking for distribution/agency agreements for products/services in the UK; are seeking sales/marketing or business development support in the U/Globally; and have a need for sales & marketing support projects

Gill Davies,

Gareth Kempson, Suzanne Morgan, Alan Morgan,

ZooBiotic Ltd is based in Bridgend, South Wales and manufactures and markets larvae products for the treatment of sloughy and necrotic wounds. All products are produced in accordance with current European 'Good Manufacturing Practice' (GMP) requirements in our state-of-the-art aseptic facility. 'Free range' LarvE® and our BioFOAM® Dressings are Zoobiotic Ltd's core products. BioFOAM® dressings consist of larvae that are enclosed in net pouches which contain pieces of hydrophilic polyurethane foam. The BioFOAM® Dressings can be left on a wound for up to 5 days. Each dressing is supplied in a plastic oyster as well as a paper/polythene bag which acts as a microbial barrier and is permeable to air. The 'free range' LarvE® are applied directly to the wound and seek out areas of slough or necrotic tissue. They are concealed in a net dressing or similar. 'Free range' LarvE® can be left on a wound for up to 3 days. LarvE are supplied in a sterile container with a lid that is permeable to air and acts as a microbial barrier.

SHOWCASES

Boots Centre for Innovation Physicool, a unique stretchy reusable bandage with an interesting story, has been launched by the Boots Centre for Innovation. Available on sale through the Boots website, this is yet another product to be launched by the Centre, a not-for-profit organisation that seeks out innovative health and beauty products at any stage – from concept to shelf ready – for Alliance Boots pharmacy-led stores. When Physicool is applied to a physical strain or injury the temperature of the affected area drops significantly, about 10C15C. It can be used straight out of the pack, without prior need to freeze or introduce ice as with other solutions. The cooling and compression provide instant treatment for inflammation and bruising of muscles, tendons and ligaments; by rapidly reducing swelling and pain, the bandage helps to speed up the healing process. The cooling effect lasts approximately 2-3 hours; even after the bandage has been removed it works by drawing heat out through rapid evaporation, whereas other products work by conducting cold in. The Physicool range comprises four products: three bandage sizes which address different body areas, and a recharge solution allowing further use from exhausted bandages - which can be washed as necessary.

The Boots Centre for Innovation team spotted the unique product at an exhibition - the NHS Healthcare Innovation Expo - earlier this summer

Dragons’ Den. Due to confidentiality, Kay couldn’t disclose to the Centre that she’d won significant investment until completing her episode. After discussions on how they could capitalise on the media attention, the Centre were able to bring forward the launch on www.boots.com to coincide with the TV show in August 2009.

BBC’s Dragons’ Den are currently discussing with Kay about featuring Physicool in a follow-up programme that tracks the dragon’s investment and involvement in the company. Boots and the Boots Centre for Innovation may well be featured in this opportunity. Aside from the Dragons’ Den, Physicool is also supported by famous cricket player Andrew Flintoff. Andrew’s been using the product for pain relief and to accelerate recovery from persistent injury problems for some time. Physicool is in talks with Andrew’s agent for future endorsement, making additional media attention very likely.

and identified them as a strong potential addition to the Boots first aid range. Whilst the process of adoption was underway, the Director of Physicool, Kay Russell, secretly filmed her pitch to the notoriously shrewd panel of investors on the BBC

Boots Centre for Innovation Institute of Life Science, University of Swansea, Swansea, SA2 8PP Wales, UK Tel: + 44 (0) 1792 513 722 Email: info@bootsinnovation.co.uk Web: www.bootsinnovation.com

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DTR DTR Medical - the rapidly growing specialist in sterile single-use surgical instruments - is seeing a significant rise in enquiries from many parts of Europe, Middle East and beyond, underlining the growing need for high quality disposable equipment. DTR Medical believe there are several factors influencing the increase in sales for sterile single-use equipment. Firstly, sterile disposables reduce the risk of cross-

contamination. Complications like surgical site infections and extended hospital stays are minimised, which lower costs and reduce potential litigation. Secondly, disposables rule out reprocessing – the need to clean reusable instruments. Reprocessing is a difficult and timely process, often leading to delayed patient throughput and raised costs from high manual handling rates. Another positive with single-use disposables is that they don’t need constant validation and repair, which is expensive and can disrupt theatre procedures if reworking is delayed. Lastly, with reusable equipment there is the issue of replacement capital: busy units demand multiple sets to cope with high patient numbers. This is even more expensive where reprocessing is done away from the clinical location, making funding often much more than anticipated.

GX Systems These cumulative cost-saving and patient benefits are being noticed far and wide. During a recent international ENT symposium in London - the 27th Politzer Society leading surgeons from across Europe expressed interest in using DTR Medical’s single-use instruments in their own clinical practice. Some delegates were so committed to these

potential benefits, that they placed orders during the meeting. Single-use surgical instruments are not designed to replace all re-usable items, but are most effective when used selectively to resolve a combination of the above factors. Managers of sterilisation services are acutely aware of these issues and welcome the support disposable products bring them. For instance, validating the sterility of long lengths of tubing is often problematic: DTR Medical eradicates this problem by supplying its range of pre-cut lengths of sterile silicone tubing, which are now being sold in markets as far afield as New Zealand.

To help hospital efficiency, single-use disposable instruments must be of a consistent high quality, but also be readily available at all times. DTR Medical takes particular care to ensure every instrument meets specification and it uses a wide range of manufacturing processes to ensure these can be reproduced repeatedly.

In order to keep up with the need of its users, the company is always improving and re-evaluating its systems. DTR Medical recently changed its method of manufacturing a series of medical instruments – the Frazier Suction Handle Range – in order to allow for greater flexibility and efficiency. The range, used across most surgical specialities, now includes two and four tip fenestrations. This modified manufacturing process has enabled the potential for more lines of products. A similar approach has been used to produce a range of sterile single-use Tibbs Arterial Cannula, which are used in many vascular procedures. Growing international demand means DTR Medical must plan ahead, and this is creating new partnerships with Welsh Universities to deliver major new lines, including important developments in gynaecological surgery. DTR Swansea SA6 8RF Tel: +44 1792 797910 Fax: +44 1792 797955 Email: adavidson@dtrmedical.com Web: www.dtrmedical.com

The Dynamic Gastric Model (DGM) is a state-of-the-art simulation of human gastric processing. A truly ‘dynamic’ in vitro system, it replicates the biological functions of the human stomach. The GX Design team took an existing prototype and through collaboration with their client transformed the artificial stomach into an exciting exploratory tool for the medical industry. The brief given to GX Design Engineers by their client PBL began at the client’s Norwich based “Model Gut” laboratory at the Institute of Food Research (IFR). Here, the in-use prototype was introduced to functional upgrades, which resulted in the improved - and now commercially attractive - second-generation DGM. The DGM provides predictive simulations of the key conditions and processes which take place in the human stomach. Real foods and meals are processed in real time, providing digested samples for further analysis with full data readout via complex computer software control. Previous to GX Design Engineer’s input, the DGM consisted of several independent systems in order to facilitate full operability. GX Design Engineers optimised the design by combining multiple systems and introducing new design elements. The upgrades enabled their client to take the newly branded DGM to market, primarily aiming at the food and pharmaceutical industries. The process begins in the newly designed Charge Station. Acid and enzyme fluids are stored for dispensing in a stable, temperature controlled environment. Here, fluids can be quickly and easily refilled

before being accurately pumped to the Processing Station via a ‘pulse free’ pumping system. The Processing Station is based upon a three-stage modular design which replicates the physical mixing of food and gastric secretions that occur in the human stomach. The initial stage takes place in a flexible funnel into which food is entered and mixed with acids and enzymes. As a result, specialist materials and finishes were selected to chemically resist the corrosive nature of stomach acid. This proved technically challenging when incorporating transparency into the design in order to facilitate viewing of food materials being processed. Food is then fed into the second stage of the process, which simulates the digestive activities of the lower part of the human stomach (antrum). Located in the central column of the Processing Station, food is subject to simulated physiological shear from a completely redesigned valve system. This novel design improves functionality through increased flow channel diameter and reduced dead volumes, resulting in increased reliability and achieves closer characteristics to the human stomach it is modelled upon.

In the third stage food material then leaves the Model via a new valve designed to give minimal sample loss, into a sample container now accessible without process interruption. This facilitates discrete sampling of the digesta output. Simulated digesta can then be analysed and taken on to an additional stage simulating duodenal digestion. GX Design Engineers have implemented new ideas and developments spawned from a dynamic working relationship with their client. “GX Design Engineers have taken a basic prototype and skilfully woven new features and improvements into the design in a relatively short timescale. We are really excited to see the new DGM in all its working glory”, said Dr Martin Stocks, Business Development Manager of PBL and the Model Gut unit.

GX Systems The Mayfield Usk, Monmouthshire, Wales NP15 1SY United Kingdom Tel: +44 1291 673437 Fax: +44 1291 673438 Email: claire@gxl.co.uk Web: www.gxl.co.uk

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The National Centre for Product Design and Development Research (PDR)

Wales’ largest bioscience conference, exhibition and biopartnering event.

17th and 18th March 2010 The Vale Hotel, Golf & Spa Resort, Hensol near Cardiff, UK*

PDR – The National Centre for Product Design and Development Research – was employed by Pro Medical Innovation, A Cardiff based venture, to produce ‘proof of concept’ prototypes as the company embark upon the commercialisation of Safeceps™

BioWales 2010 sessions will feature: • Translational Research – what is it? • Stem Cells – industrialisation for drug development and therapy. • Point of care diagnostics. • Cancer Genetics. • Futurewatch – an introduction to what’s hot and new in bioscience today.

PDR have produced the latest version of demonstration prototypes to help secure latter-stage investment and take this revolutionary medical product to market.

Biopartnering Event at BioWales 2010 Run by Enterprise Europe Network Wales and linked to the EU Enterprise Europe Network, the Biopartnering event provides a catalogue of high quality technology profiles and a base allowing one to one meetings to discuss partnering opportunities.

The Safeceps™ are a modern-day plastic adaptation of the traditional obstetric forceps. The product encompasses a number of patented technologies which allow for the categorical measurement of traction and compressive force exerted upon the fetal head during instrumental delivery. The Safeceps™ are used in conjunction with a monitoring software system (called the SafeGuard™) which visualises and records the measurement data in real-time, changing a subjective operation to a systematic and evidenced based procedure. Creation of a proof-of-concept unit required the application of state-ofthe-art prototyping and design technology. Challenges included encapsulating an electronically embedded three-dimensional metal component within a thin biocompatible elastomeric. A number of units had to be produced in days

BioWales 2010

BioWales 2010 introduces the Welsh bioscience sector to an international, commercial, academic and NHS audience. BioWales features : • Presentations from innovative companies and academia • Face to face partnering meetings • Spotlight on bioscience exhibiting companies • Workshops • 2 days of networking opportunities

Speakers for stem cell session include:

and to a very high standard. Using technologies such as selective laser melting and vacuum casting alongside traditional tool-making skills, a number of successful units were produced and the necessary investment was secured.

PDR Western Avenue Cardiff CF5 2YB T: 02920 416725 F: 02920 416973 E: dharper@pdronline.co.uk W: www.pdronline.co.uk

• Stephen Minger, GE Healthcare • Nobel Prize winner, Professor Sir Martin Evans • Anthony H Davies, Geron Corporation

To make the most of BioWales 2010 register NOW at – www.biowalesevent.com *Just 2 hours from London, 30 minutes from Cardiff International Airport with ample free parking.