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TIDBITS® COMPARES SIZES by Janet Spencer Come along with Tidbits as we are amazed by the sizes of things! NATURE’S SUPERLATIVES • The tallest redwood tree ever found was 379 feet tall, which is 74 feet taller than the Statue of Liberty. A man standing next to a redwood is proportionately equal to an ant standing next to a fishing pole 13 feet long. Redwood needles are only 1/4 inch to 1 inch long. It takes 6,000 seeds to weigh one ounce, and the cones are only an inch long. • The General Grant sequoia, a famous tree in California, contains enough wood to build a village of 50 six-room houses. It’s estimated to be 1,700 years old. Sequoias can live 3,000 years or more, and are among the oldest of living things. A sequoia’s roots cover 3 or 4 acres. They don’t start to bear seeds until age 70, and don’t reach the peak of seed-bearing until age 300. Their seeds are only the size of a pinhead. The odds of each seed surviving are about a billion to one. Their bark is up to 2 feet thick, protecting them from insects, diseases, and fire. It’s nearly as fireproof as asbestos. The only things that can kill mature sequoias are a change in climate, earthquakes, erosion, and man. In ancient times, sequoias used to live all over the world. Nearly 20% of sequoias were killed during the fire season of 2021.
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TIDBITS of Kootenai County, Idaho Issue #22 May 30th 2022
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Evelyn Bevacqua Howe 212. W. Ironwood Dr., Suite D,# 224, Coeur d'Alene, ID 83814 Cell: 208.755.9120 Email: Tidbitscda@gmail.com www.tidbitscda.com Facebook/tidbitscda
NATURE’S SUPERLATIVES •
There is a fungus growing three feet underground in Washington state which is one of the largest living things on the planet. It covers 1,500 acres, and it grows by inches, devouring dead organic material in its path.
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A large thundercloud may hold 150,000 tons of water, enough to fill a pond a mile long, 300 feet wide, and 5 feet deep.
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The mountain on the Canary Islands casts a shadow 200 miles long, said to be the longest shadow on earth.
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When calculating the height of Mt. Everest, researchers concluded the mountain was exactly 29,000 feet tall. However, they figured such a conveniently round numeral would seem as if it had been rounded off, so they announced that the mountain was 29,020 feet high.
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The highest mountain in the U.S. east of the Rockies is Mt. Mitchell in North Carolina, which is 6,688 feet tall.
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Colin and Donna Craig-Brown were weeding their garden near Hamilton, New Zealand, when they dug up what turned out to be the world’s largest potato, weighing in at 17.4 lbs. They named the spud “Doug” because they dug it up.
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Here's a grill tip just in time for Memorial Day: When you need to cook something that needs covering (say, chicken) alongside something that does not (like hot dogs), simply invert an aluminum roaster/cake pan over the needs-covering item. You can purchase smaller size pans that can be reused. -- JoAnn
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"I have a tip about taking medicine. Regardless of the size of the pill, I always feel as if it is stuck in my throat. I have started to have a chunk of banana after taking a pill. I don't get that stuck feeling anymore." -- T.B. in New Hampshire
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"The sticky residue from price tags can be really annoying. I use WD-40 to get it off. Works every time for me!" -- J.K. in Alabama
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"Painting stairs? This tip will save your life! Paint every other step to start with. When they are dry, go back and paint the others. This way, you can use the staircase anytime during your project. This is particularly important if the stairs are the only way to get to bed after a long day of painting!" -- I.L. in Nevada
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Mix a quarter cup of salt in with two tablespoons of bath wash for a sudsy, refreshing, skin-soothing salt scrub.
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To travel with pleated skirts, use this packing trick: Turn the skirt inside out, and straighten all the pleats. Then tape the bottom so that all the pleats are held together. Next, feed the skirt into a leg of pantyhose with the foot cut off. You'll end up with a nice tube, which you can tuck into the side of your luggage.
ANIMAL FACTS •
One of the best types of caviar comes from the beluga sturgeon, a fish which can live up to 3 centuries, grow up to 24 feet long, and weigh over a ton.
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Elephant ears can be five feet wide, which aids their hearing. They can hear sounds up to two miles away and can smell a human more than a mile away.
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The feet of an elephant have a combined surface area of 3.5 sq. ft., so their weight is evenly distributed and they hardly leave any tracks. A stiletto heel has a greater pressure per square inch than an elephant's foot. (cont)
TIDBITS of Kootenai County, Idaho Issue #22 May 30th 2022 ANIMAL FACTS (cont) •
Hippos are the third largest land mammals, after rhinos and elephants.
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Bald eagles mate for life. They construct the largest bird nests in the world. The largest recorded bald eagle nest, located in St. Petersburg, Florida, was 9.5 feet in diameter, 20 feet deep and weighed almost 6,000 pounds. By contrast, most hummingbird nests are less than an inch wide.
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The elf owl of southwestern U.S. and Mexico is the smallest owl at only 6" tall. The great gray owl of Alaska and Canada is the biggest, with a wingspan up to 5 feet wide.
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Fossil shark teeth found near Chesapeake Bay were 5 inches long. The prehistoric shark they came from must have been large enough so that a man could have easily stood upright between its jaws. The largest shark ever caught in contemporary times had teeth 3 inches long and was 30 feet long.
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The largest member of the cat family is the Siberian tiger, which is about 10 feet long (nose to tip of tail) and weighs about 600 lbs.
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The giant clam can be 4 feet wide and weigh 500 lbs., but there has never been a documented case of a man stepping into one and being trapped underwater when the clam closed on his foot.
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The largest bat is called the flying fox. Its wingspan is over 5 feet and its body is the size of a pigeon's. It's a vegetarian and eats only fruit, flowers, nectar, and buds. Since it depends on sight to find food rather than sonar, it has better sight than most bats. The dreaded vampire bat weighs only l oz. with a wingspan of 12", and eats a tablespoon of blood a day, usually from cattle. (cont)
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® of Dallas TIDBITS of Tidbits Kootenai County, Idaho Issue #22 May 30th 2022 County
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HUMAN HEIGHTS (cont) •
The Tutse tribe from Rwanda and Burundi in central Africa are the tallest people in the world. The men average six feet. On the other hand, the Mbuti Pygmies of the Congo are the smallest, with men averaging only four feet six inches.
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Chandra Bahadur Dangi of Nepal stood only 1 foot, 9 inches. He toured with the circus and died at the age of 75 in 2015.
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Pauline Musters was a Dutch girl who weighed only 9 lbs. and was 23 inches tall when she died at the age of 19 in 1876, making her the smallest woman in history.
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Robert Wadlow of Illinois was born in 1918 weighing 8 1/2 lbs. He grew normally until the age of two. But by the time he reached the age of 14, he had shot up to 7 feet 5 inches. He died at the age of 22 from blood poisoning from an infection caused by an illfitting ankle brace. He was 8 feet 11 inches tall at the time.
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Jon Brower Minnoch, who holds the record for the heaviest human in history, was 6 foot 1 inch and weighed about 1,400 lbs. when he married a 110-lb. woman named Jeanette in 1978 setting a record for the greatest difference in weight between a married couple. He fathered her two children. He then set a world record for greatest weight loss ever recorded, dropping to 476 lb. He died at the age of 41 weighing 798 lbs. Sun Mingming of China and his wife Xu Yan are the world's tallest couple. Sun stands 7 feet 9 inches, his wife Xu is 6 feet 2 inches, for a combined height of 13 feet 11 inches.
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At 7-feet, 9-inches tall, Sun easily towers over everyone else in the room. Xu stands just shy of 6-feet, 2-inches tall.
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In 1984, Nigel Wilks of Great Britain was 6 feet 6 inches tall when he married Beverly Russell, who suffered from a skeletal disorder and was only 3 feet 11 inches tall.
By Lucie Winborne • Idaho is the only U.S. state to explicitly declare that cannibalism is illegal. •
In 2001, the FBI warned Russell Crowe that al-Qaeda were planning to kidnap him as part of a "cultural destabilization plot." For nearly two years, the agency guarded the actor in public, but refused to provide him with any details about the threat.
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In Germany, folks who urinate in the streets are called "wildpinklers," meaning "free pee-ers."
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Gorillas sing happy songs while they eat -louder when enjoying a favorite food.
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Talk about election fraud! In 2013, police in the Maldives arrested a coconut for loitering near a polling station during the presidential election. The fruit's offense? Locals feared it might have been imbued with a magic spell to influence the election, as there was a Surah (chapter from the Quran) written on it. The coconut was released upon being found to be fake.
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In 2014, over 2.8 million American dogs were on an antidepressant drug similar to Prozac.
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Alarmed neighbors of a couple in Sydney, Australia, called the police after hearing a woman screaming, furniture crashing and a man shouting: "I'm going to kill you, you're dead! Die! Die!" When the law arrived on the scene they found, however, not a typical case of domestic violence, but a frenzied attempt to kill a spider.
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Now here's a good reason to call your plumber: A leaky faucet dripping once every second can waste up to 3,000 gallons of water in a year -- enough for 180 showers!
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The U.S. government gave Indiana University $1 million to study ... memes.
Thought for the Day: "Yesterday's home runs don't win today's games." --Babe Ruth (c) 2022 King Features Synd., Inc.
TIDBITS of Kootenai County, #46 Nov. TIDBITS of Kootenai County, IdahoIdaho IssueIssue #22 May 30th 2022 15th 202115th 2021
By Healthy Exchanges
Grilled Burgers Fire up the grill! There's something about cooking and eating outside that just can't be duplicated indoors. 16 ounces extra-lean ground turkey or beef 3/4 cup finely chopped onion 1/2 cup plus 1 tablespoon (2 1/4 ounces) dried fine breadcrumbs 1/4 cup reduced-sodium ketchup 2 teaspoons prepared yellow mustard 1 teaspoon prepared horseradish 1 teaspoon Worcestershire sauce 1/4 cup fat-free milk 1. In a large bowl, combine meat, onion and breadcrumbs. Add ketchup, mustard, horseradish, Worcestershire sauce and milk. Mix well with hands until well-combined. 2. Using a 1/2 cup measuring cup as a guide, shape into 6 patties. Place on hot grill, and grill for about 6 minutes on each side or until desired doneness. Good served on small hamburger buns or eaten as "steaks." Makes 6 servings. * Each serving equals: 175 calories, 7g fat, 15g protein, 13g carbohydrate, 199mg sodium, 1g fiber; Diabetic Exchanges: 2 Meat, 1/2 Starch/ Carbohydrate (c) 2022 King Features Syndicate, Inc.
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® of Dallas TIDBITS of Tidbits Kootenai County, Idaho Issue #22 May 30th 2022 County
1. Doctor Strange in the Multiverse of Madness (PG-13) Benedict Cumberbatch, Elizabeth Olsen 2. The Bad Guys (PG) animated 3. Sonic the Hedgehog 2 (PG) James Marsden, Jim Carrey 4. Firestarter (R) Zac Efron, Ryan Kiera Armstrong 5. Everything Everywhere All at Once (R) Michelle Yeoh, Stephanie Hsu 6. Fantastic Beasts: The Secrets of Dumbledore (PG-13) Eddie Redmayne, Jude Law 7. The Lost City (PG-13) Sandra Bullock, Channing Tatum 8. The Northman (R) Alexander Skarsgard, Nicole Kidman 9. Family Camp (PG) Tommy Woodard, Eddie James 10. The Unbearable Weight of Massive Talent (R) Nicolas Cage, Pedro Pascal Source: Box Office Mojo (c) 2022 King Features Synd., Inc.
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Young Puppy Just Can't 'Hold It' DEAR PAW'S CORNER: We adopted a puppy last month. "Jake" is having some problems adjusting to his new home. He has soiled his own bed three times so far (we crate him at night) and doesn't make it through the day -- he starts whining by the door around lunchtime and, if we're not home, will just go anywhere in the house. How can we fix this? -- Carl B., via email DEAR CARL: How old is Jake? It sounds like, barring any unknown physical issues or illness, he is a young puppy with a small bladder. He simply can't hold it as long as a fully grown dog. The fact that Jake makes it a point to whine by the door means that the house training is effective, but you may be waiting much too long to take him out. When he has to go, he will go. That includes soiling his crate, which is an absolute last resort for a dog. Follow this guideline, published by the American Kennel Club, called the "month-plusone" rule: Take your puppy's age in months, and add one. That gives you a rough estimate of the maximum number of hours Jake should wait before going outside to pee or poop. For example, if Jake is four months old, add one to that number. The total, five, means he should be taken outside every five hours. Every puppy is different, so Jake may need to go out a little sooner. And yes, that means he may need to go out in the middle of the night, or on a pee pad. He should always be taken out just before bedtime and first thing in the morning, regardless of his age. Send your questions, comments or tips to ask@pawscorner.com. (c) 2022 King Features Synd., Inc.
® of Dallas TIDBITS of Tidbits Kootenai County, Idaho Issue #22 May 30th 2022 County
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Video On Demand 1. Blacklight (PG-13) Liam Neeson 2. Spider-Man: No Way Home (PG-13) Tom Holland 3. Moonfall (PG-13) Halle Berry 4. Sing 2 (PG) animated 5. Jackass Forever (R) Johnny Knoxville 6. Black Site (R) Michelle Monaghan 7. House of Gucci (R) Lady Gaga 8. Ambulance (R) Jake Gyllenhaal 9. Marry Me (PG-13) Jennifer Lopez 10. Encanto (PG) animated DVD, Blu-ray Sales 1. Spider-Man: No Way Home (PG-13) Sony Pictures/Marvel 2. Turning Red (PG) Disney 3. Moonfall (PG-13) Lionsgate 4. Blacklight (PG-13) Universal 5. Sing 2 (PG) Universal 6. Spider-Man 3-Movie Collection* (PG-13) Sony Pictures/Marvel 7. Yellowstone: Season 4 (TV-MA) Paramount 8. Encanto (PG) Disney 9. Jackass Forever (R) Paramount Home Entertainment 10. Scream (R) Paramount *Re-release Source: ComScore/MediaPlay News (c) 2022 King Features Synd., Inc.
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TIDBITS Kootenai County, Idaho(334) Issue #22 May 30th 2022 ForofAdvertising Call 505-0674
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By Dr. Holly Carling
MONTHLY MISERY A woman’s monthly cycle isn’t anything we really want, but it is a fact of life. It’s not so bad when it is healthy, but when it isn’t, it can be truly miserable! As with everything else that goes amiss with our bodies, if you are having miserable periods, we need to find out why. Taking medications for PMS (Pre-Menstrual Syndrome) or PMDD (PreMenstrual Dysphoric Disorder) may help temporarily, but it doesn’t resolve the problem. Menstrual issues can be an imbalance of several different hormones: estrogen, serotonin, progesterone, luteinizing hormone, and folliclestimulating hormone. The organs and glands responsible for the balance of hormones include the hypothalamus, pituitary, ovaries, and the uterine lining. For those with PMDD we need to also explore the health of the intestines, blood, brain and central nervous system to see why serotonin levels may be too low and emotions too volatile. Several things are taken into consideration when evaluating the cause of a symptomatic menstrual cycle. Is the period a healthy 28 days in between
or are they abnormally longer or shorter than that? How long is the bleed? 3 days or is it carrying on longer than that? Is the flow dark and heavy, does it have clots, or is it light and thin? What symptoms do you have before or during your cycle? Breast tenderness, emotional lability, cramps, swelling of fingers, breasts or ankles, bloating, change of bowels, sugar cravings, angry outbursts, irritability, etc. are not “normal” symptoms, but indications that things are not balanced. Each of the above 2 paragraphs contain symptoms or signs that are each treated differently. They have different causes. Different organ or gland involvement and require different responses. After good investigative work to put together the puzzle pieces, figuring out the underlying causes, the use of diet, herbs, acupuncture and lifestyle modifications can make a huge difference in how the monthly cycle manifests. This should not be a time of misery. It should come and go without any of the symptomatic fanfare. There is hope for easier cycles.
Dr. Holly Carling is a Doctor of Oriental Medicine, Licensed Acupuncturist, Doctor of Naturopathy, Clinical Nutritionist and Master Herbologist with over four decades of experience. Dr. Carling is a “Health Detective,” she looks beyond your symptom picture and investigates WHY you are experiencing your symptoms in the first place. Dr. Carling is currently accepting new patients and offers natural health care services and whole food nutritional supplements in her Coeur d’Alene clinic. Visit Dr. Carling’s website at www.vitalhealthcda.com to learn more about Dr. Carling, view a list of upcoming health classes and read other informative articles. Dr. Carling can be reached at 208-765-1994 and would be happy to answer any questions regarding this topic.
ForofAdvertising Call 505-0674 TIDBITS Kootenai County, Idaho(334) Issue #22 May 30th 2022
by Freddy Groves
A Jumble of Wait Times for VA Medical Care A recent audit by the Department of Veterans Affairs Office of the Inspector General outlined what so many of us already knew -- that it's difficult to understand the wait times for appointments and medical care at the VA. It seemed to some of us that the rules changed day by day, that our appointments were at the whim of whatever program was being followed at the time and that there was no transparency about how those dates were calculated. Turns out that we were right all along. In a perfect world, wait times at the VA always begin with an accurate starting point. If, for example, a veteran wants to seek civilian care because the wait is too long at the VA, he doesn't qualify for that outside care until he's waited a certain amount of time. Precisely when that period of time begins is at the heart of the problem. Since 2014, the OIG discovered, the VA has used various methods of calculating wait time and figuring out when the criteria is met to seek civilian care. The rules for those calculations were in writing back to 2014. But without following those rules consistently, wait times varied and wandered all over the place. It didn't help that the website gave misleading information about how dates were to be calculated, with differences between wait times for new patients and what was written in the scheduling directive. Enter the OIG, with its excellent investigators who always leave no stone unturned. While the recent audit doesn't assign blame (which the OIG won't hesitate to do when it's called for), the VA knew about these problems. The OIG has officially asked the VA to respond and let them know what steps they're going to take to fix this. To read the details, go to www.va.gov/oig/pubs/ VAOIG-21-02761-125.pdf. Don't miss the timeline on the cardiology patient whose provider wanted him seen pronto. There was a 66 day wait. (c) 2022 King Features Synd., Inc.
1. What artist released albums titled "Texas Flood" and "Couldn't Stand the Weather"? 2. Why did the Moody Blues originally call themselves "The M Bs" and "The M B Five"? 3. Which Laura Branigan song was used in the film "Flashdance," but wasn't included on the soundtrack album? 4. What artist had a hit with "Total Eclipse of the Heart"? 5. Name the song that contains this lyric: "There ain't nothin in the world like a big-eyed girl, To make me act so funny, Make me spend my money." Answers 1. Stevie Ray Vaughan, in 1983 and 1984. When Vaughan died in a helicopter crash in 1990, he left behind a wealth of material. Since then, a number of tribute specials and posthumous albums have been released, some of them charting globally. 2. They were hoping for an endorsement from the Mitchells & Butlers Brewery. It didn't happen. 3. "Gloria." The other one, "Imagination," was used. "Gloria" nabbed a Grammy nomination for Best Female Pop Vocal in 1982. 4. Bonnie Tyler, in 1983. 5. "Chantilly Lace," by the Big Bopper in 1958. Jerry Lee Lewis followed with a cover in 1972. Over the years, numerous other artists have either released covers or samples in their own songs. (c) 2022 King Features Syndicate
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TIDBITS Kootenai County, Idaho(334) Issue #22 May 30th 2022 ForofAdvertising Call 505-0674
1. U.S. STATES: Which state is the smallest in land area? 2. MEDICAL: What is a common name for the medical condition called hyperlipidemia? 3. PSYCHOLOGY: What is the abnormal fear represented by peccatophobia? 4. FOOD & DRINK: What fish is the basis of Worcestershire sauce? 5. GEOGRAPHY: Nuuk is the capital of which island constituent country? 6. U.S. PRESIDENTS: Which state has produced the most presidents? 7. ART: In which major city would you find the Uffizi Gallery? 8. MOVIES: What is the main setting of the "Mama Mia!" movies? 9. MYTHOLOGY: What is the name of the Greek god of wine? 10. GENERAL KNOWLEDGE: Where is the rock formation called Giant's Causeway located? Answers 1. Rhode Island 2. High cholesterol 3. Fear of committing sins or imaginary crimes 4. Fermented anchovies 5. Greenland 6. Virginia, with eight presidents 7. Florence, Italy 8. Skopelos, Greece 9. Dionysus 10. Northern (c) 2022 King Features Synd., Inc.
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® of Dallas County TIDBITS of Tidbits Kootenai County, Idaho Issue #22 May 30th 2022
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On June 6, 1683, the Ashmolean, the world's first university museum, opens in Oxford, England. Today, the collection at the Ashmolean Museum of Art and Archaeology ranges in time from the earliest implements of man, made about 500,000 years ago, to 20th century works of art. • On June 10, 1692, in Salem Village in the Massachusetts Bay Colony, Bridget Bishop, the first colonist to be tried in the Salem witch trials, is hanged after being found guilty of the practice of witchcraft. The witch trials, which resulted in the executions of 19 innocent women and men, ended in October. • On June 9, 1893, the interior of Ford's Theatre collapses when a basement pier gives way, killing 23 people. The building -where President Lincoln was assassinated -housed hundreds of government clerks. • On June 7, 1942, the Battle of Midway -one of the most decisive U.S. victories in its war against Japan -- comes to an end. The outnumbered U.S. Pacific Fleet destroyed four Japanese aircraft carriers with the loss of only one of its own, the Yorktown. • On June 8, 1968, James Earl Ray is arrested in London, England, and charged with the assassination of civil rights leader Martin Luther King Jr. In 1969, Ray pleaded guilty to King's murder. Three days later, he attempted to withdraw his guilty plea, claiming he had been set up as a patsy in a larger conspiracy. • On June 11, 1979, film actor John Wayne, born Marion Morrison, dies at age 72. The "John Wayne" name was created when the director of "The Big Trail" didn't think Marion was a good name for an actor playing a tough Western hero. • On June 12, 1982, a large crowd descends upon New York City's Central Park, demanding nuclear disarmament. Estimates placed the number of attendees at over a million. (c) 2022 Hearst Communications, Inc. All Rights Reserved
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By Matilda Charles Walk Faster, Live Longer We've known for years that walking is a good form of exercise for seniors ... we just didn't know why. Now a new study not only explains how it works, but why brisk walking is even more effective. Ten years ago, researchers at Leicester University Biomedical Research Centre started looking at genetic data in the biobanks in the U.K. for clues about why seniors who walk seemed to live longer. They didn't fool around with a dozen or so participants. No, they analyzed the information of over 405,000 people. And now we know: It's the telomere length. Telomeres (aka leucocyte telomere length, or LTLs) are the "end caps" on strands of DNA, the building blocks of our bodies and an indicator of our biological age. Fast walkers have longer LTLs, and therefore better health ... and longer lives. That same study showed that as little as 10 minutes per day of brisk walking can equate to longer lives. (The Mayo Clinic prefers 30 minutes of activity per day, possibly broken into three 10-minute sessions.) The best walking pace appears to be 3 mph, although the research data was from wearable tracking devices like those we use to measure steps per day. But there's more. A study at the National Institutes of Health concluded that the length of the telomeres is positively associated with consuming fruits, dairy, 100% fruit juice and coffee. On the other hand, food and drinks with high amounts of sugar and red meat can negatively affect the telomere length. The study gave a big thumbs up to the Mediterranean diet, with loads of nuts, fruits, vegetables, unrefined cereals, fish and olive oil. If you invest in a pedometer to measure your steps, be sure to look for one that tracks your speed. Ask your doctor about any recommendations they have for the trackers. (c) 2022 King Features Synd., Inc.
NEWLY DISCOVERED ALZHEIMERS GENES FURTHER HOPE FOR FUTURE TREATMENTS NEW YORK (CNN) — An analysis of the genetic makeup of more than 94,000 people in the United States and Europe with clinically diagnosed Alzheimers led to the discovery of four new genetic variants that increase risk for the neurodegenerative disease. These genes, along with others previously identified, appear to work in tandem to control bodily functions that affect disease development, the study found. "This is a powerful study, and a step forward for our understanding of Alzheimer said neurologist Dr. Richard Isaacson, who directs the Alzheimes Prevention Clinic at Weill Cornell Medicine. Finding these new genes allows clinicians to one day target these genes with therapeutic interventions said Isaacson, who was not involved in the study. "It also gives us a greater insight to potential causes of Alzheimer The studys findings will not change anyones day-to-day life or medical practice any time soon," said Heather Snyder, the Alzheimer Association senior director of medical and scientific operations, who was also not involved in the new research. That said, they do give us potentially useful insights into the bodily processes that may cause or interact with the changes of Alzheimers disease and other dementias,; Snyder added. Unprecedented numbers Led by a team from the University of Miami’s Hussman Institute for Human Genomics, an international consortium of researchers analyzed data collected by four centers, two in the United States and two in Europe, that make up the International Genomic Alzheimers Project. The study, published Thursday in the journal Nature Genetics, was the second genome-wide association study to be performed by the group on individuals with known Alzheimer's compared to a group of controls. The first study, published in 2013, looked at nearly 75,000 people and identified 11 gene or locations, that had not been previously known to be associated with the development of Alzheimers. By increasing the numbers to 94,000, the new study added 30 percent more data to the analysis, allowing the researchers to verify 20 previously found genes and add four. How the new genes — IQCK, ACE, ADAMTS1 and WWOX — along with a previously discovered gene called ADAM10, affect the development of Alzheimers is under investigation. But once their specific functions are understood and examined, researchers say they will be able to begin to develop potential drug targets. "Alzheimers is a complex disease. Its not like Huntingtons or Parkinsons, where one gene is altered and you get the disease," said
Linda Davis Director of building relationships. 208.457.3403 www.LodgeLiving.net
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senior author Dr. Margaret Pericak-Vance, director of the Hussman Institute. With Alzheimers multiple genes acting together Pericak-Vance said. We were trying to get at the very rare gene variants that could contribute to Alzheimers. And we couldnt do that before. We just didnt have the sample size to do it. The study validated the previously discovered role of amyloid and immune system genes in the development of Alzheimers, said Harvard professor of neurology Rudy Tanzi, director of the Alzheimers Genome Project and a member of the international consortium. We had seen amyloid early on, but it had not been verified in a (genome-wide association study) Tanzi said. "So I think one exciting thing is that it brings us back to amyloid as a major player. I should also say that were also seeing that the other major pathway besides the amyloid is innate immunity, Tanzi said. "In this study we’re seeing even more innate immune genes affecting one susceptibility to neuroinflammation. A susceptibility to neuroinflammation is key, Tanzi says,because at the end of the day, plaques and tangles may set the stage, but it's neuroinflammation that kills enough neurons to get to dementia. Now having more than a dozen gene targets on how immunity ties into Alzheimers, Tanzi said, should really facilitate a new drug discovery Precision medicine. The increase in sample size allowed the researchers to discover hubs of genes" that might impact the development of Alzheimers. And some of those genes have the potential to have more than one function," said lead author Brian Kunkle, an associate scientist at the Hussman Institute. They may be increasing risks through different disease pathways, Kunkle said. Prediction of risk and treatment for each individual will rely on what type of changes a person has in each of those 25 genes or other biomarkers. Isaacson said the ongoing work could lead to precision medicine at its finest. A person can take many different roads to Alzheimers Isaacson said. If we can find out what road a person is on through identifying certain genes, we can target specific interventions that may work preferentially for that specific person. As to when that might occur, Kunkle is cautiously optimistic. Its difficult to say if it will help someone that has Alzheimers now, he said. Hopefully, we will have treatments developed for their family members that may have these genes that are putting them at risk. Please call for a tour of our “HOMES,” for truly they are…
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TIDBITS of Kootenai County, Idaho Issue #22 May 30th 2022
By Ryan A. Berenz 1. What American military leader reportedly declined an offer to be Commissioner of Baseball in 1961? 2. Basketball Hall of Famer Kareem Abdul-Jabbar's signature one-handed post move shot was known by what nickname? 3. On Nov. 17, 1990, Houston Cougars quarterback David Klingler set an NCAA record for touchdown passes in a single game with how many? 4. Name the racehorse who won both the Kentucky Derby and Preakness Stakes in 1987, but had his Triple Crown attempt spoiled at the Belmont Stakes. 5. What university in Queens, N.Y., has the nickname "Red Storm" for its athletic teams? 6. Name the brand of beer that had naming rights to the Milwaukee Brewers' home ballpark from 2001-20? 7. What NASCAR driver won the Daytona 500 four times and won three consecutive Cup Series championships from 1976-78?
Answers 1. Gen. Douglas MacArthur. 2. The Skyhook. 3. 11. 4. Alysheba. 5. St. John's University. 6. Miller. 7. Cale Yarborough. (c) 2022 King Features Syndicate, Inc.
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ARIES (March 21 to April 19) A heads-up alert to all free-spirited Ewes and Rams: Be wary of a deal that could result in compromising your independence. Check every detail before making a commitment. TAURUS (April 20 to May 20) New facts emerge that help put an irksome workplace situation in perspective. Meanwhile, pay more attention to a family member who needs your wisdom and strength. GEMINI (May 21 to June 20) A slight setback in plans is nothing to worry about. Use this delay to deal with a number of matters you might have ignored for too long. Expect news from someone in your past. CANCER (June 21 to July 22) You're entering a period of stability. Use it to straighten out any outstanding problems related to a very personal situation. Also, pay closer attention to financial matters. LEO (July 23 to August 22) As much as you love being a social Lion, you might well benefit from staying out of the spotlight for a while. You need time to reflect on some upcoming decisions. VIRGO (August 23 to September 22) A difficult family situation improves, thanks to your timely intervention. You can now start to focus more of your attention on preparing for a possible career change. LIBRA (September 23 to October 22) An onthe-job change works to your benefit by offering new opportunities. It's up to you to check them out. Meanwhile, a stalled romantic situation starts up again. SCORPIO (October 23 to November 21) That flare-up of Scorpian temperament cools down, leaving you more receptive to suggestions about changes that might need to be made in your personal life. SAGITTARIUS (November 22 to December 21) An unusual period of indecisiveness is a mite frustrating. But things soon clear up, allowing the sage Sagittarian to make those wise pronouncements again. CAPRICORN (December 22 to January 19) You might feel that you know best, but it's not a good idea at this time to try to force your opinions on others. Best advice: Inspire change by example, not by intimidation. AQUARIUS (January 20 to February 18) Some setbacks could affect your plans to fortify your financial situation. But things start moving again by early next week. Meanwhile, enjoy your resurgent social life. PISCES (February 19 to March 20) Show that often-hidden steely spine of yours as you once again stand up to an emotional bully. You've got the strength to do it, especially as friends rally to your side. BORN THIS WEEK: Your ruling planet, Mercury, endows you with a gift for writing. Have you considered penning the world's greatest novel? (c) 2022 King Features Synd., Inc.
TIDBITS of Kootenai County, Idaho Issue #22 May 30th 2022
TIDBITS PUZZLE ANSWERS
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TIDBITS of Kootenai County, Idaho Issue #32 Aug 9th 2021
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