2021 U-M Kellogg Eye Center Annual Report

Page 35

Big Data, Collaboration, and Impact Couple recognizes great potential to advance care for eye conditions— and offers critical support

that even top-tier academic medical centers like the W.K. Kellogg Eye Center see only a small number of cases each year. Improving care for patients with those conditions therefore requires communication and collaboration among

WE SEE TREMENDOUS POTENTIAL

TECHNOLOGY, AND SOPHISTICATED

eye centers nationally. A large repository of rich data from what will eventu-

Jeff and Wendy Eisenshtadt are fueling momentum with a gift to the SOURCE data repository

IN LEVERAGING BIG DATA, INFORMATION ANALYTICS TO POSITIVELY IMPACT

Some eye conditions are so uncommon

HEALTH CARE, AND THIS IS A GREAT

ally number about three dozen academic medical centers and health systems from across the

EXAMPLE OF THAT IN ACTION. — Wendy Eisenshtadt

country will make that possible. Led by Kellogg faculty, the Sight OUtcomes Research Collaborative (SOURCE) repository is uniquely linking clinical data from electronic health records with data from ocular diagnostic tests,

Wendy and Jeff Eisenshtadt of Bloomfield Hills. The couple recently made a philanthropic gift to support SOURCE. “We see tremendous potential in leveraging big data, information technology, and sophisticated analytics to positively impact health care, and this is a great example of that

in action,” Wendy Eisenshtadt says. “We want to

help it gain even more momentum.”

In one project, Lindsey B. De Lott, M.D., M.S., an assistant

environmental and community-level factors, and more to build

professor of ophthalmology and visual sciences as well as

a more complete picture of risk factors and outcomes of care

neurology, will be studying optic neuritis, an uncommon condi-

for patients with ocular diseases. Researchers will use the reposi-

tion that occurs when inflammation in the optic nerve causes

tory, which already includes data on more than 7 million patient

an acute, often severe disruption in vision in one or both eyes.

visits, as well as sophisticated machine learning and artificial

The study will bring together the expertise of clinicians, statisti-

intelligence tools, to identify ways to improve treatments and

cians, data analysts, and others. “It is really powerful to be able

outcomes for eye diseases.

to study data that combines the experiences of centers across “By pooling data across many sites,

the country to understand more about

we are increasing racial, ethnic, and

conditions like this, which are relatively

geographic diversity — and the number

infrequent,” Dr. De Lott says. “The goal

of cases we can study,” says Joshua D.

is to create a tool that will help us deter-

Stein, M.D., M.S., an associate professor

mine how to get these patients the right

of ophthalmology and visual sciences

treatment at the right time.”

and of the School of Public Health’s

Researchers from all of the organiza-

department of health management and

tions submitting data to SOURCE will

policy. “We can then build robust predic-

have access to the repository so that they

tive models that will enable us to identify the most appropriate

can pursue similar efforts — for rare and common conditions,

therapy for a given patient at the most appropriate time, to

Dr. Stein says. “There are many ways we can use this resource to

achieve optimal outcomes.”

move toward more personalized eye care. We’re very grateful for

It is an exciting opportunity to help patients, particularly

the Eisenshtadts’ generosity and for their belief in our mission.”

those who are facing rare, sight-threatening conditions, say 33


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Articles inside

Toward a Therapeutic Target for Proliferative Vitreoretinopathy

2min
page 25

State-of-the-Science Microscope Gives Kellogg Researchers New Edge

2min
page 25

Michigan Medicine to Establish Neural Engineering Training Program

2min
page 21

Endocrine Society Award

1min
page 21

Leading on the National Stage

2min
page 15

Marshall Parks Lecture at AAO

1min
page 13

Prioritizing Communication for Patient Safety

2min
page 13

New Faculty Members

3min
page 42

Alumni Highlights

4min
page 39

Recognizing Distinguished Alumni Richard Gutow, M.D., and Gary Gutow, M.D.

6min
pages 36-37

Guarding Photoreceptor Metabolism to Prevent Vision Loss in Inherited Retinal Diseases

2min
page 31

Big Data, Collaboration, and Impact

3min
page 35

A Visionary Legacy

3min
page 33

Eyes on the Future

3min
page 34

Kellogg’s Latest Heed Fellows

3min
page 32

U-M Learners Produce Online Newsletter

3min
page 29

Next-Generation Tools to Treat Abnormal New Ocular Blood Vessels

3min
page 28

Genetically-Modified Occludin Shown to Protect Against Diabetes-Related Vision Loss

2min
page 30

Innovation in Action

3min
page 24

New Pediatric Ophthalmology Fellowship in Ghana

3min
page 27

Kellogg Addresses Technician Shortage with Ongoing Training Program

2min
page 26

Kellogg Researcher Launches First of-its-Kind Study of Health and Aging in Kenya

2min
page 23

A New Regulator of Retinal Angiogenesis Discovered

2min
page 22

Lipid Droplets May Protect Against AMD

2min
page 20

Mapping the Genetic Landscape of Nanophthalmos

2min
page 19

Training Eye Disease Researchers in India

2min
page 18

Kellogg Leads International Team Linking Family’s Symptoms to Rare, Inherited Syndrome

4min
pages 14-15

Clinical Research Update: Patient Perspectives

4min
page 17

Finding New Pathways for the Treatment of Choroideremia

2min
page 16

Finding a Personalized Solution for Dry Eye

3min
page 12

Vitreoretinal Lymphoma: from Symptoms to Diagnosis to Treatment

5min
pages 4-5

In it Together

5min
pages 10-11

Collaborating to Deliver Specialized Care

3min
pages 8-9

Steno North American Fellowship

2min
page 5

The Chair’s Perspective

2min
page 3

Kellogg Offers Multiple Options for Limbal Stem Cell Deficiency

3min
page 7

COVID-19 Transmission Risk in Cornea Transplantation

2min
page 9

NIH-Funded Pilot Program Addresses Disparities in Glaucoma Care

3min
page 6
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