Department of Medicine Annual Report 2015

TRANSFORMING LIVES D E p a r t m e n t o f Med i c i n e c h a i r m a n ’ s Re p o r t 2 0 1 5

Table of Contents

1 Chair’s Message

2

Division Chiefs

2

By the Numbers

3 Administration

3 Chief Residents

8 Endocrinology, Diabetes and Metabolism 10 Gastroenterology 12 General Internal Medicine 14 Geriatrics and Palliative Medicine 16 Hematology-Oncology 18 Hepatology 20 Hospital Medicine 22 Infectious Diseases 24 Nephrology and Hypertension 26 Population Health and Computational Medicine 28 Pulmonary, Allergy, Critical Care and Sleep Medicine 30 Rheumatology and Immunology

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34 High Impact Publications

38 Diversity

39 Philanthropy

40 Residents and Fellows

Division Reports

Editor: Miriam Barros 4 Cardiovascular Director, Business Operations 6 Clinical Pharmacology Department of Medicine Design, Editorial and Project Management Consulting: Sabia Communications, Inc.

Published by the Chairman's Office of the Department of Medicine of the University of Miami Miller School of Medicine.

All contents, Š2015 University of Miami.

Reproduction in whole or in part without previous written permission by the editor is prohibited.

Education Programs

through education, research and service

U H ea l t h | U n i v er s i t y o f M i a m i M i l l er S ch o o l of Med i c i ne

Chair’s Message Welcome to the Department of Medicine at the University of Miami Miller School of Medicine. The Department, which was created soon after the founding of the medical school in 1952, currently has more than 341 full-time clinical and research faculty, and over 300 voluntary faculty. Throughout the years, the Department of Medicine has evolved into the largest department not only at the medical school, but in the entire University.

Our goal is to continue to make groundbreaking new discoveries that transform lives through clinical care, research and service to our students and community. Our world-renowned scientists are recognized for their technical expertise and creative discoveries that often lead to the development of new techniques, technological advancements, and the cure and prevention of life-threatening diseases.

Cultural awareness is also a key priority in our enterprise as we strive to cultivate leadership from underrepresented minorities and provide the highest level of patient-centric medicine for the variety of communities we serve.

The clinical mission of the Department of Medicine encompasses both inpatient and ambulatory care settings, with the clinical program including Jackson Memorial Hospital, the third largest teaching hospital in the United States. With more than 1,550 inpatient beds, Jackson Memorial Hospital allows the Department to provide care to the most underserved populations in South Florida. In addition, the 560-bed University of Miami Hospital is the region’s first university-owned, multi-specialty, acute care hospital and the flagship facility of UHealth - University of Miami Health System. Boasting all-private rooms, the Hospital provides patients with personalized treatment in a high-quality environment. The Bruce W. Carter Veterans Administration Medical Center, with more than 400 beds, has 81 acute medical beds stationed within the cardiac and medical intensive care units.

Our educational mission is to produce versatile physicians who are astute clinicians, innovative researchers, skilled educators, and community leaders with a passion for medicine. The Department of Medicine trains over 336 house staff annually in residency and sub-specialty fellowship programs, the largest group of trainees in any department.

House staff provide clinical care in almost every institution within the UHealth, Jackson Health systems, and the

Veteran’s Administration (VA). Our training programs extend to regional campuses in both Palm Beach (JFK Hospital) and Broward (Holy Cross Hospital) counties. We participate with the Harrington Latin American Training Program, serving as host to a large number of international trainees. Additionally, the Department of Medicine has a significant number of faculty serving in leadership roles in both undergraduate and graduate medical education. Many of these faculty leaders have received numerous awards for teaching excellence at the local, regional and national level.

As medicine in the United States moves towards more innovative models of care delivery, the Department of Medicine is poised to take a leadership role in developing the paradigms necessary to deliver care to large populations both locally and nationally. The new Division of Population Health and Computational Medicine will address the principles of large dataset analytics, while the application of such knowledge will assist in the design and execution of interventions to treat disease and maintain wellness.

By working closely with faculty in the Department of Medicine and throughout the rest of the University, we will utilize both theoretical and applied innovations that deliver solutions to the most pressing of human problems, including the treatment of disease and maintenance of health on a global scale. These exciting new models of care delivery will integrate the genomic data of populations to allow for precise therapeutic interventions, providing a platform for the Department to educate the next generation of specialized and highly-trained physicians.

We invite you to learn more about the many outstanding programs at the Department of Medicine.

Roy E. Weiss, MD, PhD Professor of Medicine Chair, Department of Medicine Kathleen and Stanley Glaser Distinguished Chair in Medicine University of Miami Miller School of Medicine

Making New Discoveries D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

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Division Chiefs Division chiefs from left to right, top: Robert C. Hendel, MD, Interim Chief, Cardiology, Matthias A. Salathe, MD, Pulmonary, Allergy, Critical Care and Sleep Medicine; Richard A. Preston, MD, Clinical Pharmacology; Oliver Lenz, MD, Interim Chief, Nephrology and Hypertension; Mario Stevenson, PhD, Infectious Diseases; Paul Martin, MD, Hepatology; Eric Greidinger, MD, Rheumatology and Immunology; Joseph D. Rosenblatt, MD, Hematology-Oncology.

Bottom: Ernesto Bernal-Mizrachi, MD, Chief, Endocrinology, Diabetes and Metabolism; Olveen Carrasquillo, MD, General Internal Medicine and Interim Chief, Geriatrics and Palliative Medicine; Roy E. Weiss, MD, PhD, Chair, Department of Medicine; Maria T. Abreu, MD, Gastroenterology; David M. Seo, MD, Division Chief, Population Health and Computational Medicine; Efren Manjarrez, MD, Interim Chief, Hospital Medicine.

By the Numbers Clinical Activity (per year) Procedures

Admissions

University of Miami Hospital (UMH)

22,151 UMH 1,305 UMHC/SCCC 5,154 VA 373 Medical ICU 38,963 JMH

1,216 Catheterization 7,195 Gastroenterology University of Miami Hospital and Clinics (UMHC)/ Sylvester Comprehensive Cancer Center (SCCC)

Transplants (including Pediatrics)

5,547 Endoscopies 54 Bronchoscopies

204 Kidney 71 Liver 10 Pancreas 11 Kidney/Pancreas 16 Intestine 7 Heart 5 Lung

Veterans Affairs (VA)

125 Bronchoscopies 2,303 Colonoscopies Outpatient

158,661 UMH 358,721 UMHC/SCCC

New Patient Visits

Divisions in the Department of Medicine

22,151 341 Inpatient Admissions

Faculty

29.6

$

MILLION

13.5

$

Total NIH Revenue

2,900 Pulmonary 1,400 Allergy Clinical revenue from the DEPARTMENT OF MEDICINE 50

245

Residents and Fellows

Total Grant and Contract Revenue

MILLION

VA (Primary Care)

MILLIONS OF DOLLARS

36,147 14

152 Active Awards

204,672 693,742 Outpatient Visits

40 30 20 10

RVUS

0

2

FY 2011

FY 2012

FY 2013

FY 2014

FY 2015

U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Administration From left to right, top: Marilyn Glassberg, MD, Vice Chair for Innovation and Diversity; Michael Kolber, MD, Vice Chair for Clinical Affairs; Thomas Hooton, MD, Chief of Medicine, Miami VA; Matthias Salathe, MD, Vice Chair for Research; Stefanie Brown, MD, Vice Chair for Education.

Bottom: Anna C. Herman-Giddens, Vice Chair; Miriam Barros, Director, Business Operations; Roy E. Weiss, MD, PhD, Chairman, Maritza Suarez, MD, Associate Vice Chair, Quality; Jennifer Marks, MD, Vice Chair for Appointments and Promotions.

Chief Residents From left to right: Kevin Dholaria, MD, Cesia Gallegos, MD, Sofia Palacio, MD, Nicholas Kaknes, MD, Roy E. Weiss, MD, PhD, Professor and Chairman, Department of Medicine Morgan Allyn Sendzischew, MD, Archana Ramireddy, MD, Tameka Joseph, MD and Conrad Macon, MD.

Leadership The art of transformational leadership is at the center of great institutions. These institutions are enabled to become great by the relentless work of innovative leaders.

Former President Donna Shalala and Dean and Executive Vice President for President Julio Frenk Dean Pascal Goldschmidt Former President Donna Shalala Health Affairs Pascal Goldschmidt have guided the University of Miami and the Miller School of Medicine into the future with visionary current members of the University of Miami community leadership. in a common journey of building a better Univeristy In August of 2015, the dawn of a new era began as the together.

University of Miami ushered in its sixth president, Julio These executives set the tone for the Department Frenk, MD, MPH, PhD. Dr. Frenk is a physician, former of Medicine so it can go on to positively transform lives dean at Harvard University and the former Minister of through teaching, research, and service with a global Health for Mexico. He arrives with fresh ideas, shared perspective. The Department of Medicine is proud of its aspirations, and boundless excitement to join the past and partners and extremely grateful for their leadership.

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Cardiovascular Division Elite cardiovascular care in South Florida The Cardiovascular Division at the Miller School of Medicine continues to be at the forefront of clinical cardiac care. The Division offers a wide spectrum of diagnostic testing and therapeutic interventions across several South Florida locations (Miami, Boca Raton, Plantation and Kendall). With more than 10,000 outpatient visits annually, the Division treats a wide variety of cardiac disorders including coronary artery disease and valve abnormalities, and works continually to create a positive and lasting imprint throughout the community.

The Cardiovascular Division is comprised of 30 faculty members engaged in key disciplines, including electrophysiology, cardiac imaging, interventional cardiology, cardiac rehabilitation and heart failure.

Interventional Structural Cardiology Expanding Dramatically The Division of Cardiology and the International Medicine Institute are pleased to launch the first International Structural Heart Disease Interventional Fellowship. This program is designed to provide training in structural heart disease procedures for fellows with prior cardiac catheterization and interventional cardiology experience.

Structural heart disease describes a condition in which a patient has inherited (congenital) or acquired defects or both, compromising the integrity of the heart’s valves or chambers. These complications can range from a lack of communication between two chambers, as in atrial septal defect or patent foramen ovale; valvular heart disease, such as aortic stenosis/regurgitation or mitral stenosis/regurgitation; or closure of certain pockets of the upper chambers.

The Division’s Institute has great expertise in catheterbased treatment of structural heart disease and has been one of the leading sites for transcatheter aortic valve replacement (TAVR) research with high enrollment in both the Partners trials and the CoreValve Pivotal trials. The Division also has significant experience with mitral valve,

atrial septal defects and complex congenital therapy.

With the entire field of interventional structural cardiology expanding dramatically, future leaders will be expected to be exceptional clinicians and skillful operators.

Additionally, they will be tasked with discovering and implementing novel technologies that can better tackle the special challenges seen in this blossoming field. The University of Miami and the International Medicine Institute recognized the need to train these future leaders and have taken advantage of strategic relations with centers outside of the United States, where new technologies are developed and used for the first time in human subjects.

Over the past eight years, the Division has worked in partnership with a high-volume clinical site in Cali, Colombia, Angiografia de Occidente, to spearhead cardiovascular research projects, including TAVR and mitral therapies. This site has performed multiple firstin-man and pre-Federal Drug Administration (FDA) research. Additionally, it was the first certified TAVR site, as well as left atrial appendage (LAA) exclusion treatment area, and the only location in South America to be performing Mitraclip.

The University will establish the first International Structural Heart Disease Fellowship between the two sites. An additional month of research and imaging

Eduardo de Marchena, MD, FACC, FACP, FSCAI Associate Dean for International Medicine Professor of Medicine and Surgery Assistant Director, Cardiovascular Fellowship Training Programs Director of Interventional Cardiology

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Division FACULTY LIST

training will be provided at the premier cardiac research center for cardiovascular disease in Europe, the Thorax Center at Erasmus University in Rotterdam, Netherlands.

At the Thorax Center, fellows will be working directly with pioneers in the field of structural heart disease interventions, with an emphasis in procedure planning, as well as 3D modeling and printing of cardiac anatomy.

This novel approach facilitates identification of procedural obstacles before taking the patient to the catheterization laboratory. Moreover, as the field of structural heart disease evolves, 3D modeling will become an essential tool for training physicians about structural procedures.

During this year-long interventional training, fellows are expected to master the risks, techniques and indications of the following procedures: Transseptal left heart catheterization, atrial septal defect/ patent foremen ovale (ASD/PFO) closures, percutaneous balloon valvuloplasty of aortic and mitral disease, TAVR, Mitraclip, and LAA exclusion treatment of perivalvular leaks.

Furthermore, the fellows will be encouraged to participate in activities related to device design and innovation. The field of structural heart interventions is rapidly evolving, and the fellows training at the program will be uniquely prepared to collaborate in the developing, prototyping and optimizing of new technologies for the treatment of structural pathologies of the heart.

This unique Fellowship will help bridge international cooperation for the next generation of structural interventional cardiologists and will serve as a model for future training programs.

New Faculty at the Division The Division of Cardiology is proud to announce the addition of two faculty members set to join the team in Fiscal Year 2016. Jeffrey Goldberger, MD will join the Division as its new Chief of Cardiology. Dr. Goldberger comes from Northwestern University, where he served as Professor and Director of the Cardiac Arrhythmias Program at the Center for Cardiovascular Innovation.

Dr. Goldberger also served as Director of Clinical Cardiac Electrophysiology Research at Northwestern Memorial Hospital.

The Division also announced that Litsa Lambrakos, MD will join the electrophysiology group. Dr. Lambrakos completed her Cardiac Electrophysiology and Cardiovascular Disease Fellowships at Columbia University/New York Presbyterian Hospital.

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Robert C. Hendel, MD Interim Division Chief (Through October 31, 2015) Director, Cardiac Imaging and Outpatient Services, Director, Cardiac Care Unit and Cardiology Service Chief, University of Miami Hospital Professor of Medicine and Radiology Professors of Medicine Nanette H. Bishopric, MD Director, UM/Florida Heart Research Institute Cardiovascular Genomics Laboratory Simon C. Chakko, MD Chief, Cardiology Miami Veterans Affairs Medical Center Eduardo J. De Marchena, MD Associate Dean for International Medicine Pascal J. Goldschmidt, MD Senior Vice President for Medical Affairs and Dean Joshua M. Hare, MD Director, Interdisciplinary Stem Cell Institute Alberto Interian, MD Robert J. Myerburg, MD Rafael F. Sequeira, MD Professors of Clinical Medicine Maureen H. Lowery, MD Clerkship Director of Internal Medicine at UMMSM Associate Professors Martin S. Bilsker, MD Director, Echocardiography Laboratory, University of Miami Hospital; Outpatient Cardiology Clinic, Jackson Memorial Hospital Mauricio G. Cohen, MD Director, Cardiac Catheterization Laboratory Chunming Dong, MD Raul Mitrani, MD

Associate Professors of Clinical Medicine Claudia A. MartinezBermudez, MD Carl E. Orringer, MD Eugene J. Sayfie, MD Medical Director, Executive Health Alan H. Schob, MD Medical Chief, Catheterization Laboratory, Miami Veterans Affairs Medical Center David M. Seo, MD Chief Medical Information Officer Howard J. Willens, MD Assistant Professors of Medicine Juan Viles-Gonzalez, MD Lina Shehadeh, PhD Assistant Professors of Clinical Medicine Carlos E. Alfonso, MD Cardiology Fellowship Program Director Sharon N. Andrade-Bucknor, MD Medical Director, Cardiac Rehabilitation Program Antonio Barquet-Leon, MD Eugene J. Bauerlein, MD Sandra Chaparro, MD Director of Heart Failure Clinic; Director of Heart Failure/Transplant Fellowship Program Roberto A. Miki, MD Robert B. Stang, MD Research Assistant Professor Jianqin Wei

$2.5M MHRI Research Grant Award The Division is delighted to announce that the Miami Heart Research Institute (MHRI) was recently awarded a $2.5 million research grant. These funds are to be used exclusively in support of cardiac research and the results of these studies will be made freely available to the public through appropriate scientific channels.

The Miami Heart Research Institute, whose mission is to stop heart disease through research, education and prevention, has been an international leader in cardiovascular research and education since 1944.

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Division of Clinical Pharmacology Transcending our mission through clinical research The Division of Clinical Pharmacology, which is dedicated to the investigation of the effects of new pharmacological agents and disease mechanisms in humans, is proud of its long and established record of successful research across a wide range of therapeutic areas.

Located within the self-contained Clinical Pharmacology Research Unit, the Division of Clinical Pharmacology can be found directly on the Miller School of Medicine campus and has four core missions (1) Undertake original research to investigate the mechanisms of drug action in humans (2) Design and conduct special populations phase I research studies (3) Support the Miller School of Medicine research infrastructure and (4) Conduct phase I studies across a wide range of therapeutic areas.

The University of Miami Medical School complex has three large teaching hospitals along with their associated specialty clinics. As one of the largest medical centers in the United States, the Phase I unit draws from a huge patient population base and a large number of specialty clinics. The Division interacts closely with clinical investigators and supports a wide array of clinical research.

INVESTIGATION OF POTASSIUM HANDLING

BY THE KIDNEY PUBLISHED IN 2015 The human body must maintain a normal serum potassium concentration in order to ensure proper function of the heart and internal organs. A high potassium concentration (hyperkalemia) can result in an abnormal cardiac rhythm and may lead to cardiac arrest.

Therefore the body must eliminate excess potassium quickly and efficiently in order to maintain a normal serum potassium concentration.

The main way the body regulates potassium balance is through excretion of excess dietary potassium through the kidney. According to the traditional formula, the increase in serum potassium concentration that follows a potassium-containing meal is the primary determinant resulting in increased potassium excretion. The increased potassium concentration directly increases renal potassium excretion by the kidney and also stimulates hormones which further amplify potassium excretion. Thus, potassium balance has traditionally been understood as a negative feedback system determined primarily by an increase in the serum potassium concentration.

But an increase in potassium concentration may not be the only trigger to increase renal potassium excretion.

Recent laboratory investigations suggest there is a novel gastrointestinal-renal kaliuretic signaling axis originating in the gastrointestinal tract that directly senses ingested potassium and then signals the kidney to increase renal potassium excretion in response to food intake. This axis is hypothesized to be mediated by sensors located in the gastrointestinal tract that detect ingested potassium and

Nadine Francois, MA prepares samples for long-term storage in the laboratory at -80 degrees Centigrade. Following the collection of samples for all study participants, the 5001500 samples are sent to a reference laboratory for analysis.

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rapidly initiate the release or activation of factors that signal the kidney to produce an acute increase in renal potassium excretion.

To test this axis in humans, researchers conducted a series of potassium handling experiments in random order that demonstrated a rapid increase in potassium excretion with no increase in serum potassium concentration that persisted despite blocking the hormone aldosterone.

These findings suggest that a mechanisms for potassium excretion exists independent of the classical physiological mechanisms. The experiments provide data that supports the existence of a novel gastrointestinal-renal kaliuretic signaling axis in humans that mediates a share of the potassium excretion that follows a complex potassiumcontaining meal independent of changes in serum potassium concentration and aldosterone. This axis appears to function alongside the known mechanisms mediated by changes in extracellular potassium concentration and may offer an auxiliary mechanism for potassium excretion.

Pharmacokinetics in the study of how the body processes a medication A large study of the pharmacokinetics and safety of a new antibiotic drug in patients with liver disease was conducted in 2014-2015. Specifically, the Division studied the absorption from the stomach and gastrointestinal tract, distribution within the body, and the elimination by the kidneys and liver of a medication. The study of the pharmacokinetics and safety of new medications is a central mission of the Clinical Pharmacology Research Unit. The Clinical Pharmacology Research Unit has an international reputation for conducting complex

Richard A. Preston, MD, MSPH, MBA Division Chief Professor of Clinical Medicine

Professor of Medicine Barry J. Materson, MD, MBA

Research Associate Professor David Afshartous, MD

pharmacokinetic studies in patients with kidney and liver disease. The Division recently conducted a large study of a new antibiotic medication that included 24 study participants with liver disease and 24 matching healthy volunteers. Normally such a large study would be divided between several centers. The results of this study suggest that this new medication is safe in patients with liver disease and requires no dose adjustment. The testing of new medications in patients with kidney and liver disease are key steps in the drug development and approval process

HOW SALT RAISES BLOOD PRESSURE TO CAUSE HYPERTENSION This past year, the Division continued its work towards understanding how the kidney regulates the amount of sodium in the body and helps to control blood pressure.

The kidney is responsible for maintaining total body sodium within a range that is suitable for normal blood pressure as well as control of the body’s fluid volumes.

The goal of these studies is to better understand a newly discovered pathway by which certain sodium transporters in the kidney regulate the amount of sodium that the kidney excretes. The results of this interesting study should be available in the coming year 2016-2017.

Miriam Gonzalez Sosa, MA prepares to collect blood samples for pharmacokinetic and safety laboratory analysis. The Clinical Pharmacology Research Unit conducts approximately 15-20 clinical research studies each year in a variety of patient populations.

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Division of Endocrinology, Diabetes and Metabolism Innovation in research and excellence in clinical care Exciting things are happening in the Division of Endocrinology, Diabetes and Metabolism. First, Ernesto Bernal-Mizrachi, MD was appointed Chief of the Division. His research interests involve understanding the molecular mechanisms that govern growth and survival of islet beta-cells, while his experiments focus on the importance of an insulin signaling pathway in the regulation of beta-cell mass, function and plasticity. The information gained via these studies positively affect the treatment of diabetes, since they uncover potential targets that can be developed into new pharmacologic agents.

These agents are then designed to augment survival and proliferation of beta-cells in vivo and in vitro.

Among other responsibilities, Dr. Bernal-Mizrachi will be spearheading a multi-departmental Comprehensive Diabetes Center (CDC) for patients with Type 2 Diabetes and obesity. The CDC is working tirelessly to improve patient care and accelerate the growth of clinical programs that combine the expertise of endocrinologists, cardiologists, cardiac and vascular bariatric surgeons, and podiatrists.

The CDC will be located on the main University of Miami campus, as well as at the satellite facilities. In addition to the diabetes program, Dr. Bernal-Mizrachi hopes to expand various endocrinology initiatives including a pituitary clinic, an endocrine oncology clinic, and a weight management and bone program. Dr. Bernal -Mizrachi envisions an expansion of the Division’s research enterprise that will include new initiatives in adipocyte biology, appetite control and clinical research, as well as the continued development of his own program on beta cell functions. Studying beta cell function helps identify new pathways useful in the treatment of diabetes and obesity.

Despite the rapid increase of endocrine disorders such as obesity, diabetes and thyroid cancer, the Division has kept up with the demand for treatment with its diverse expertise as well as its expansion to satellite clinics. Practice locations currently include the UM main campus, Kendall, Miami Lakes and Deerfield. Additionally, endocrinologists provide inpatient care at the University of Miami Hospital, Sylvester Cancer Center, Jackson Memorial Hospital and the Veteran’s Administration (VA) Hospital.

In other news, a one-of-a-kind Dynamic Endocrine Testing Center based at the Diabetes Research Institute 8

(DRI), provides accurate and dependable endocrine function testing. By standardizing all procedures and protocols, the Division is able to provide reliable interpretation of endocrine testing results for all its patients.

Pituitary and neuroendocrine experts are active leaders of national and international medical societies that specialize in providing care to patients with pituitary tumors and other diseases. The Pituitary Program is quickly expanding, with a variety of new initiatives coming to fruition including coordinated neurosurgery, radiation oncology, and endocrinology visits that include expert opinion on complex cases. The Division’s Adrenal Program has expanded to offer periodical adrenal vein sampling for the diagnosis of primary hyperaldosteronism or Conn Syndrome. The Division often collaborates with the neurosurgery and interventional neurology teams to exchange information about complex diagnostic and therapeutic procedures including petrosal vein sampling for the diagnosis of Cushing’s disease, and endoscopic transphenoidal pituitary surgery.

Distinguished educator, researcher and clinician, Roy Weiss, MD, PhD, is internationally recognized for his studies on thyroid disease, as well as for his clinical skills and academic leadership. Dr. Weiss joined the Division and became the Department Chair in 2014.

Advancing the Understanding of Diabetes and Autoimmunity The Diabetes Research Institute (DRI), a Center of Excellence at the University of Miami, Miller School of Medicine, continues to be a leader in islet cell transplantation, which offers a potential cure for diabetes.

DRI investigators, led by Rodolfo Alejandro, MD and Camilo Ricordi, MD, recently announced that the first test of a novel transplant technique for insulin-producing cells was successfully completed. This Food and Drug Administration (FDA)-approved Phase I/II study builds upon decades of progress in clinical islet transplantation and is an important first step toward the development of the DRI BioHub, a bioengineered “mini organ” that mimics the native pancreas. The BioHub contains real insulin-producing cells that can sense blood sugar levels in real time, and releases the precise amount of insulin needed accordingly.

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Division FACULTY LIST

Type 1 Diabetes TrialNet is an international consortium of clinical research centers aimed at the prevention or delay of Type 1 Diabetes (T1D). TrialNet researchers at the University of Miami have made significant advancements towards identifying those who are at risk of developing the disease, and have discovered various exciting new therapies to combat it. TrialNet has created a large and effective network to screen the relatives of persons with Type 1 Diabetes for risk, to conduct trials for prevention, and to lay the foundation for future studies.

Understanding the Molecular Basis of Type 2 Diabetes Both Ernesto Bernal-Mizrachi, MD and Alejando Caicedo, MD’s research groups are currently performing studies to understand how human islets function and how ß-cells develop, grow and die. Using animal models and human islets, the current studies are aimed towards understanding the molecular mechanisms responsible for insulin secretion and how pancreatic islets adapt to diabetogenic conditions. The long-term goal of these molecular and cell biology studies is to design novel therapies for diabetes. In addition, Dr. Caicedo is exploring novel implications of the effect of neurotransmitters and paracrine signals in the control of insulin secretion. Given that Type 2 Diabetes is a multi-factorial disease, the Division is also interested in understanding insulin resistance as a result of metabolic syndrome. In this field, Gianluca Giacobellis, MD focuses on the pathophysiological role of adipocytes in cardio-metabolic diseases, such as measuring fat around the heart to help determine the risk of diabetes, cardiovascular and other obesity-related diseases.

Discovering More about Diabetes Division faculty excel in the areas of clinical diabetes, osteoporosis and pituitary disorders and are engaged in leadership positions and academic activities sponsored by influential medical societies, including the American Diabetes Association, the American Society for Bone and Mineral Research, the American Association of Clinical Endocrinologists, and the Endocrine Society.

Additionally, investigators have made seminal contributions towards understanding the biology of the human pancreas.

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Ernesto Bernal-Mizrachi, MD Division Chief Professor of Medicine

Alejandro Ayala, MD Interim Division Chief (Through August 31, 2015) Associate Clinical Professor of Medicine

Professors of Medicine Rodolfo Alejandro, MD Director of Clinical Islet Transplantation, Director of Metabolic Studies Core and Responsible Head of the Islet Cell Processing Facility at the DRI and Associate Program Director for the General Clinical Research Center at the University of Miami/Veterans Administration Medical Center Ronald Goldberg, MD Associate Director of Medical Affairs at the Diabetes Research Institute and Co-Director of the DRI Clinical Laboratory Professor of Medicine and Associate Professor of Biochemistry and Molecular Biology in the Division of Endocrinology, Diabetes, and Metabolism Gianluca Iacobellis, MD, PhD Director of the University of Miami Hospital Diabetes Service Jennifer Marks, MD Vice Chair for Appointments and Promotion, Section Chief, Endocrinology, Diabetes, and Metabolism, and Director, Diabetes Management Program, Miami VAMC Karl Muench, MD Alberto Pugliese, MD Head of the Immunogenetics Program at the DRI Jay Skyler, MD Deputy Director for Clinical Research and Academic Programs at the Diabetes Research Institute Professor of Medicine, Pediatrics and Psychology Jay Sosenko, MD Director of the MD/MPH Program Professor of Medicine, Pediatrics and Epidemiology

Roy E. Weiss, MD, PhD Chairman of the Department of Medicine Kathleen and Stanley Glaser Distinguished Chair in Medicine Associate Professors Alejandro Ayala, MD Interim Division Chief Atil Kargi, MD Fellowship Program Director and Coordinator of the Inpatient Endocrinology Consultation Service Assistant Professors of Medicine David Baidal, MD Sabina Casula, MD Diala El-Maouche, MD Violet Lagari-Libhaber, DO Bresta Miranda-Palma, MD Interim Director of the Kosow DRI Diabetes Treatment Center Maria del Pilar Solano, MD Francesco Vendrame, MD, PhD Research Professors of Medicine, Immunology and Microbiology Luca Inverardi, MD Deputy Director of Translational Research at the Diabetes Research Institute Ricardo Pastori, PhD Director of the Molecular Biology Laboratory at the DRI Research Associate Professors Alejandro Diego CaicedoVierkant, PhD Armando Mendez, PhD

Studies regarding Type I Diabetes have resulted in several high impact publications, while investigators currently review the metabolic effects of new long-acting growth hormones.

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Division of Gastroenterology Beating the odds with innovative research and breakthrough techniques This is an exciting time both for the field of Gastroenterology and the Division at the University of Miami, which continues its cutting edge work.

Gastrointestinal illnesses continue to be the most common reason patients seek medical care. The discovery and categorization of the human microbiome has revealed that intestinal bacteria regulate and control not just gastrointestinal diseases, but many other metabolic diseases, including diabetes.

The Division of Gastroenterology is committed to the threefold mission of leading research in gastroenterological diseases, offering the best medical care to patients, and educating future academic leaders in the wide and varied field of gastroenterology. Faculty members have a broad range of special research interests, including esophageal disorders, inflammatory bowel diseases (such as Crohn’s and ulcerative colitis), gastrointestinal cancer and motility disorders. The Division of Gastroenterology also continues to study pancreatic disorders, as well as advanced diagnostic and therapeutic endoscopy.

The University of Miami’s New Pancreas Center The UM Pancreas Center was founded by Jamie S. Barkin, MD in January 2015. Its mission is to advance the prevention, diagnosis and treatment of pancreatic diseases and to improve the quality of life for those living with these disorders.

Colorectal Cancer is now more easily detectable Colorectal cancer remains a major health problem in the community and colonoscopy is the most frequently performed screening modality used to prevent the development of colorectal cancer (CRC). A new innovation in the detection of CRC is the development of the Full Spectrum Endoscopy (FUSE) colonoscopy platform. The FUSE method offers a significant quality improvement in the detection and prevention of colorectal cancer.

Providing advanced care to those with Crohn’s disease and ulcerative colitis The Division of Gastroenterology continues to serve as a leading center for Crohn’s disease and ulcerative colitis within the community. Most recently, the Crohn’s and Colitis Center has undertaken an innovative dietary pilot study for those suffering from mild-to-moderate ulcerative colitis. This type of study helps address the most basic questions asked by patients, namely the role a patient’s diet plays in the development of inflammatory bowel disease (IBD).

The first motility-specific program in South Florida Under the direction of Baha Moshiree MD, MS-CI, UHealth has successfully initiated the first comprehensive motility program in South Florida. This program offers patients diagnosed with chronic gastrointestinal illnesses a specialized treatment regimen to ensure the most comprehensive management of their ailments. Countless patients suffering from disorders involving swallowing, those who have trouble emptying their stomachs (gastroparesis), or have chronic constipation or diarrhea and irritable bowel syndrome (IBS), have found relief and advice on how to best manage their illnesses.

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Division FACULTY LIST

Progressive GI Fellowship Training The University is committed to providing a progressive educational platform for the training of future clinicians, physician-scientists and medical leaders for the South Florida academic and surrounding communities. The program’s goal is to provide fellows with the clinical and scholarly ability to pursue an academic career while still adhering to the firm guidelines set forth in competency, scholarly research and teaching. Given their specialized and exacting training, UM Gastroenterology fellows are poised to become the next generation of leaders in both the clinical and academic arenas.

Tracking the Development of IBD in Cuban Immigrants Oriana Damas, MD and Maria T. Abreu, MD are currently investigating the phenotype and age of presentation of IBD in Cuban immigrants. South Florida has experienced various waves of immigrants arriving from the Caribbean and Latin America, which helps provide the unique opportunity to identify risk factors responsible for the rising inflammatory bowel disease (IBD) incidence among immigrant Hispanics. Dr. Damas and her colleagues sought to determine whether IBD onset differed based on the time period these Cubans immigrated to the United States. Thus far, the findings indicate that there is a definite relationship between IBD development and the period during which Hispanic immigrants come to the US. Interestingly, IBD often occurs sooner after arriving to the United States in later waves of Cuban immigrants. The study of IBD in migrant Hispanic populations seeks to further the understanding of how evolving environmental triggers may be at least somewhat responsible for the rise of IBD in developing countries.

Basic and Translational Research The Micky and Madeleine Arison Family Foundation Crohn’s and Colitis Discovery Laboratory, led by Maria T. Abreu, MD continues its focus on basic and translational research in the field of inflammatory bowel disease (IBD).

Dr. Abreu’s laboratory shares research interests with the Arison family in seeking new dietary

Opposite page: Dr. Abreu examining patient in Crohn’s Clinic.

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Maria T. Abreu, MD Division Chief Professor of Medicine Martin Kalser Chair in Gastroenterology, Professor of Microbiology and Immunology

Professors of Medicine Jaime S. Barkin, MD Jeffrey B. Raskin, MD, FACP, FACG, FASGE, AGAF Associate Professors of Medicine Amar Deshpande, MD, FACG Assistant Dean for Medical Education and Competency Assessment Vice Chair for Education, GI Division Jose Garrido, MD Baharak Moshiree, MD Director of Motility Afonso Ribeiro, MD Daniel Sussman, MD

Assistant Professors of Medicine Oriana Damas, MD Paul Feldman, MD Roberto Fogel, MD David Kerman, MD Director of Gastroenterology Fellowship Program Marcelo Larsen, MD Emory Manten, MD Howard Manten, MD Internist, Gastroenterology Enrico Souto, MD Director of Endoscopic Services

recommendations to manage IBD. To this end, Dr. Abreu’s research team, both at the Crohn’s and Colitis Center and in the research laboratory, was recently funded by the Broad Medical Foundation – Crohn’s and Colitis Foundation of America (CCFA) to perform a pilot study using a controlled diet with specific amounts of fat to determine if these dietary restrictions would help in the management of the disease.

Philanthropy The Division of Gastroenterology continues its tradition of outstanding fundraising in 2015.

Ms. Joanne “Joni” Trempala and her husband Dohn, who began contributing as UHealth Champion donors, continue their support of Dr. Abreu’s ongoing research.

Ms. Trempala has been a loyal friend and patient of Dr. Abreu’s for more than five years and has personally championed her innovative research into a variety of gastrointestinal ills. The family’s support and friendship is shared by Dr. Abreu, who is sincerely appreciative of their efforts on behalf of her research.

During the last legislative session, Florida State Senator Eleanor Sobel (D-Hollywood), worked to obtain funding to enhance IBD research and improve health care delivery. UHealth, which established its cutting edge Crohn’s and Colitis Clinic in 2013, received a $250,000 grant from the State of Florida. This funding will help the Crohn’s and Colitis Clinic as it provides comprehensive treatment in surroundings where patients and their families feel most comfortable.

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Division of General Internal Medicine Outstanding primary care and community based research The Division of General Internal Medicine (GIM) faculty provides the bulk of adult primary care at UHealth, conducting more than 100,000 outpatient visits in Fiscal Year 2015.

For the past 20 years, GIM faculty has been at the forefront of medical education. Since 2009, the Division has developed a robust portfolio of externally funded research through federal, state and foundation-sponsored projects. The faculty also serves as principal investigators on more than $15 million in externally sponsored awards.

The GIM Division remains exceptionally proud of its diverse faculty. At present, over 60% of clinicians hail from under-represented minority groups, and more than half of the faculty is made up of women.

GETTING THE MESSAGE OUT TO THE COMMUNITY The GIM Division is dedicated to sharing its research and medical discoveries with a much larger audience and often looks to distribute its findings beyond the traditional channels of scholarly publications read mostly by scientific and medical professionals. One example is Olveen Carrasquillo, MD, MPH, who is regularly featured in many Spanish-language television networks. Another physician who consistently reaches out to the community is Erin Marcus, MD, Associate Professor of Clinical Medicine. Prior to medical school, Dr. Marcus was an accomplished journalist, and she continues to write

articles about medically vulnerable populations in mainstream newspapers and magazines. Her articles and stories have appeared in such well-respected publications as The Atlantic, The Washington Post, The New York Times, and The Miami Herald.

Many faculty from the GIM Division hold leadership roles at UM that range from serving as deans to directors of various centers and institutes. These faculty members succeed in areas such as medical education (undergraduate and graduate), executive medicine, international medicine, quality management, medical informatics, and ethics. In an effort to further engage with the community, Division faculty are currently spearheading population health management clinical partnerships with various insurers.

Above: Dr. Marco Gonzalez using the new Intelligent Retinal Imaging System (IRIS) machine, which transmits a picture of the patient’s retina to Bascom Palmer electronically for evaluation by an ophthalmologist, at the University of Miami Hospital and Clinics practice.

Left: Dr. Marcus reviewing the Medical Knowledge SelfAssessment Program (MKSAP) materials with residents and medical students at the Jackson Memorial Hospital Ambulatory Care Center.

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Division FACULTY LIST Professors of Clinical Medicine Panagiota Caralis, MD, JD Special Assistant to the Chief of Staff and Medical Director of the Women Veterans Health Program.

Miami VA Health System Laurence Gardner, MD Executive Dean for Education and Policy Daniel Lichtstein, MD Regional Dean for Medical Education Alex Mechaber, MD Senior Associate Dean, Undergraduate Medical Education Research Professor Kenneth Goodman, PhD Director, Bioethics Program and WHO Collaborating Center in Ethics and Global Health Policy Associate Professors of Clinical Medicine Keith Custer, MD Michael Federman, MD Medical Director, Palm Beach Gardens Practice Mark Gelbard, MD Director of PBL Curriculum for MD/ MPH Program Marco Gonzalez, MD Associate Division Chief Medical Director, GIM Faculty Practice at UMHC Erin Marcus, MD, MPH Associate Director, GIM Education at Jackson Memorial Hospital

Hilit Mechaber, MD Associate Dean for Student Services Director, Honors Program in Medicine Paul Mendez, MD Director, Clinical Skills Program Assistant Dean of Clinical Curriculum Ross Scalese, MD Assistant Director of Educational Research and Technology at the Gordon Center for Research in Medical Education Joan St. Onge, MD Associate Dean for Graduate Medical Education Frederick Williams, MD Program Director, UM Regional Campus Internal Medicine Program Judi Woolger, MD Medical Director, Executive Medicine Research Associate Professor Chi Zhang, PhD Assistant Professors of Clinical Medicine Gauri Agarwal, MD Howard Anapol, MD Medical Director, GIM Faculty Practice at Coral Gables Monica Broome, MD Stefanie Brown, MD Vice Chair of Education, Department of Medicine Program Director, Internal Medicine-Pediatrics Residency Program

TAKING A GLOBAL APPROACH GIM faculty have a wide range of research interests, including minority health disparities, health services research, medical education, ethics, diabetes, cardiovascular disease, cancer, and stroke. The Division continues to grow its research and obtain funding to serve minorities and improve the health outcomes of underserved populations via grants from the National Institute of Health (NIH) and the Patient-Centered Outcomes Research Institute (PCORI). Globally, the faculty participate in research projects in Ecuador, Puerto Rico, and the Dominican Republic.

PROVIDING COMMUNITY-WIDE CARE General Internal Medicine faculty provide care at six practices throughout Miami-Dade, Broward and Palm Beach counties. Clinical services range from providing primary and preventive care, managing chronic health

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Olveen Carrasquillo, MD, MPH Division Chief Interim Division Chief, Geriatrics and Palliative Care Professor of Medicine and Public Health Sciences

Alexandra Calandriello, MD Gregory Coleman, MD Gloria Coronel-Couto, MD Yanisa DelToro, MD Medical Site Educational Director, Internal Medicine Residency Program at UMHC/Sylvester Yvonne Diaz, MD Chief Academic Officer, UHealth Bruce Eisenberg, MD Antonia Eyssallenne, MD, PhD Associate Program Director, Internal Medicine-Pediatrics Residency Program, Program Director, Pediatrics Residency Program, Hospital Bernard Mevs/Hospital St.Damian, Haiti Alexis Federman, DO Robert Federman, MD Sherin Ghali, MD Lilliam Guzman, MD Medical Director, International Medicine Brian Hagenlocker, MD Chief, Clinical Informatics, Miami VA Health Care System Melanie Helfman, MD Medical Director, CHDS Kendall Margarita Llinas, MD

Sudha Lolayekar, MD Lisa Martinez, MD Meaghan McNulty, MD, MPH Associate Director of MD/MPH Program Course Co-Director for: Doctoring; Physicianship; Integration of Public Health and Medicine; Community and Public Health Michael Mueller, MD Elizabeth Parra-Garnica, MD Hector Rivera, MD Hiram Rodriguez, MD Maritza Suarez, MD Associate Vice Chair of Quality, Department of Medicine Associate Chief Medical Information Officer, UHealth James Trice, MD Jacobo Wajner, MD Alan Yesner, MD Medical Director UHealth Boca Raton /Ft. Lauderdale Practices Amalinnette Zito, MD Research Assistant Professors Reid Cushman, PhD Sonjia Kenya, PhD Assistant Professor

conditions, tackling acute illnesses, and caring for patients with multiple advanced chronic health conditions. The Division also serves the medically indigent population at Jackson Health System, where it provided approximately 17,000 visits in Fiscal Year 2015. Continuing its rapid growth, the Division added three new faculty members this year who will assist in providing the highest quality patient-centered care to the community.

EDUCATING FOR THE FUTURE General Internal Medicine faculty are extensively involved in educating the next generation of physicians.

The faculty teach during all four years of the medical school curriculum, and deliver the bulk of instruction to residents. Always seeking innovative ways to engage students, faculty members often utilize lectures, small group discussions, problem-based learning, role playing, and simulations to better educate these future physicians.

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Division of Geriatrics and Palliative Medicine Cutting edge research and clinical care to improve quality of life The Division of Geriatrics and Palliative Medicine is dedicated to the improvement of health, independence, and quality of life for older persons. The Division also focuses on reducing the burdens of dependent persons through interdisciplinary learning and discovery.

Divisional training and research activities are based on interdisciplinary care models established and maintained by nationally and internationally recognized faculty who serve as attending physicians at facilities within the University of Miami Health System, Jackson Health System, the Miami VA Medical Center, and the Miami Jewish Health Systems. Faculty members engage in a large range of research interests including bone metabolism, diabetes, prostate cancer, regenerative medicine and palliative medicine.

EXCELLENCE IN GERIATRICS Established in 1991 to serve the older adult population in South Florida, the Miami Geriatric Research, Education, and Clinical Center (GRECC) has been funded continuously by the federal government with approximately $3 million a year. The Miami GRECC is one of only 20 Centers of Excellence in Geriatrics in the United States. In addition to leading the nation in providing cutting edge geriatric care, the Division recently graduated its first fellowship class in hospice and palliative medicine, under the inspirational guidance of Khin Zaw, MD.

RESEARCHING DISEASES THAT TARGET ELDERS Faculty members are determined to understand why certain diseases seem to target the older adult population.

Priyamvada Rai, MD, PhD, Associate Professor of Medicine, is currently investigating novel therapeutic targets in non-small cell lung carcinoma (NSCLC), a highly aggressive and treatment-resistant form of lung cancer. Another physician, Ramiro Verdun, MD, PhD, Associate Professor of Medicine, is examining DNA repair mechanisms in antibody producing cells among patients with immune system deficiency.

MOBILE AND TELE-HEALTH TECHNOLOGIES Stuti Dang, MD, Associate Professor of Medicine, is currently evaluating how brief, low-cost internet and telephone skills-building interventions can assist Spanish-speaking caregivers of elderly patients. These interventions have also shown to reduce caregiver burden and depression, as well as improve their functional abilities. In addition, this program will include online resources for stroke caregivers as well as provide an intervention strategy for clinicians throughout the Veterans Administration to use in their practice. Research

IMPROVING THE QUALITY OF TRANSITIONAL CARE Led by Jenny Drice, MD, the Division began a joint effort last year to improve transitional care and ensure the safe transfer of elderly patients between the University of Miami and Miami Jewish Health Systems. Through this joint effort, both facilities aim to improve communication among care providers, reduce hospital readmissions, and improve patient satisfaction. The Division is also working to develop a variety of tele-health technologies, including mobile apps that could be utilized to assist in the transition of care.

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Dr. Joel Danisi observes one of the Geriatric fellows examining a patient at the University of Miami Multi-Disciplinary Clinic

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Division FACULTY LIST

being led by Jorge Ruiz, MD, examines how individualized patient education and self-management information can help chronically ill patients and their caregivers better manage health problems.

LABORATORY OF E-LEARNING AND MULTIMEDIA RESEARCH (L.E.M.U.R) The Laboratory of E-learning and Multimedia Research (L.E.M.U.R) has gathered a multidisciplinary team of professionals dedicated to exploring the use of e-learning and educational technology to enhance health care education. Founded by Jorge Ruiz, MD, L.E.M.U.R. provides Division faculty with the opportunity to actively engage in the mentoring of fellows, residents, and medical students interested in educational research and scholarship.

EXCELLENCE IN LEARNING As one of the first medical schools in the nation to implement a required geriatric medicine clerkship, and the first to develop a competency-based geriatric curriculum for medical students, the Division of Geriatrics and Palliative Medicine has been a visionary leader in geriatric education for decades. In the early 2000s, faculty members led the statewide effort by the Florida Consortium for Geriatric Medical Education to develop medical student competencies for core geriatric syndromes. Building on this initial regional collaboration,

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Olveen Carrasquillo, MD, MPH Interim Division Chief (Effective September 1, 2015) Division Chief, General Internal Medicine Division Head, Health Services Research and Policy Professor of Medicine and Public Health Sciences Hermes Florez, MD, PhD, MPH Interim Division Chief (Through August 31, 2015) Director, Division of Epidemiology Director, GRECC - Miami VA Healthcare System

Professors of Medicine Silvina Levis-Dusseau, MD Guy Howard, PhD Bernard Roos, MD (Emeritus) Bruce Troen, MD (Emeritus) Michael Mintzer, MD (Emeritus) Associate Professors Evan P. Cherniack, MD Stuti Dang, MD, MPH Priyamvada Rai, PhD Jorge Ruiz, MD Carlos Perez-Stable, PhD Ramiro Verdun, PhD​ Maria Rose van Zuilen, PhD

Assistant Professors Enrique Aguilar, MD Joel Danisi, MD Jenny Drice, MD Juan Carlos Palacios, MD Osvaldo Rodriguez, MD Luis Samos-Guitierrez, MD Marcio Soares, MD Khin Zaw, MD Miriam Gutt, PhD Karin Zachow, MD

the educational faculty were involved in a national Association of American Medical Colleges (AAMC)sponsored effort to identify and define geriatric-specific competencies.

These detailed guidelines would set a performance benchmark for graduating medical students, preparing them to care for geriatric patients on the first day of residency.

The consensus-based effort resulted in a set of 26 competencies covering eight domains: Medication Management, Self-Care Capacity, Falls, Balance and Gait Disorders, Hospital Care for Elders, Cognitive and Behavioral Disorders, Atypical Presentation of Disease, Health Care Planning and Promotion, and Palliative Care.

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Division of Hematology-Oncology At the forefront of personalized medicine to cure cancer The Division of Hematology-Oncology is engaged in clinical, basic and translational research and provides expert hematologic/oncologic care at the Sylvester Comprehensive Cancer Center and affiliated community based clinics, Jackson Memorial Hospital, University of Miami Hospital, and the Miami Veterans Administration Hospital. With the introduction of the Deerfield Beach satellite unit in 2003, Kendall in 2008, Plantation in 2011, Hollywood in 2013, and Coral Springs in 2014, the Division now provides state-of-the-art hematologic and oncologic care across the South Florida region.

University of Miami hematologists-oncologists continue to make seminal contributions to the understanding of the pathogenesis of hematologic malignancies, solid tumors, and benign hematologic disorders. Investigators provide patients with a wide range of treatment options through the conduct of over 150 therapeutic clinical trials. The multilingual faculty and staff mirror the diversity in South Florida.

The hematology-oncology clinical effort is supported by a cadre of Advanced Registered Nurse Practitioners (ARNPs) with specialized expertise in selected malignancies. Many of the ARNPs hold advanced oncology certifications and/or Doctor of Nursing Practice degrees, and have presented at national meetings of the American Society of Clinical Oncology, Gastrointestinal American Society of Clinical Oncology, European Society for Medical Oncology, Florida Nurses Association, American Cancer Society, and the Oncology Nursing Society.

Several faculty have received significant awards.

Marc Lippman, MD was inducted into the Royal College of Physicians. Joseph Rosenblatt, MD received a Presidential Award of Distinction from Bar Ilan University for efforts in helping to organize a new Israeli medical school cancer program. Joyce Slingerland, MD received the Schally Research Award for her translational research in breast cancer. Jonathan Trent, MD served as the American Society of Clinical Oncology Scientific Program Committee Chair for Sarcoma, and is Editorin-Chief of a new journal, the Gastrointestinal Stromal Tumors (GIST) Cancer Journal.

New recruits in 2015 include Jonathan Schatz, MD a highly regarded National Institutes of Health (NIH)-funded lymphoma investigator from the University of Arizona, as well as Alejandra Perez MD, Carmen Calfa, MD, and Aruna Mani, MD, representing the largest breast cancer practice in the Broward region. The Division also welcomes Nicolas Acquavella, MD who hails from the National Cancer Institute, and brings special expertise in melanoma and the application of novel immunotherapies.

Gustavo Fernandez, MD, MBA was certified a Six Sigma Black Belt in 2015. Dr. Fernandez has applied stateof-the-art process improvement methodology to improve patient experience in the ambulatory and inpatient settings.

Dr. Fernandez and his team were awarded the Sterling Council Showcase Competition Award for Innovation of the Year Award in Patient Care Service by the Florida Hospital Association. The team was also awarded First Prize at the 2014 Annual Florida Sterling Conference Team Showcase.

Division Programs and Faculty The Hematology-Oncology Fellowship Program currently includes 16 fellows and is directed by Judith Deleo Hurley, MD. Dr. Hurley is assisted by Pasquale Benedetto, MD, Associate Program Director for Oncology and James Hoffman, MD, Associate Program Director for Hematology. The program is designed to maximize educational clinical and research experience in preparation for academic careers.

A Breast Cancer Fellowship has been organized under the direction of Marc Lippman, MD, for training in translational research and the multidisciplinary management of breast cancer. Many members of the Division also participate in the training of PhD candidates in the context of the Cancer Biology Program and other graduate programs.

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Hematology-Oncology Research Divisional investigators continue to develop novel cancer treatment strategies. Lynn Feun, MD, and Niramol Savaraj, MD continue groundbreaking research into developing new treatments for melanoma. Dr. Savaraj has continued research into resistance mechanisms to inhibitors of BRAF, a human gene that makes the B-Raf protein, and mitogen-activated extracellular signalregulated kinase (MEK) in melanoma.

Jaime Merchan, MD has continued to direct the Phase I Treatment Program which is currently performing over 20 active trials. The Phase I portfolio continues to grow incorporating novel agents to targeted antibody drug conjugates, pathway inhibitors, and novel immuno therapeutic approaches.

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2015 new hires

Division FACULTY LIST Joseph D. Rosenblatt, MD Division Chief Professor of Medicine, Microbiology and Immunology William J. Harrington Chair in Hematology

Nicolas Acquavella, MD

Carmen Calfa, MD

Alejandra Perez, MD

Aruna Mani, MD

Jonathan Schatz, MD

In the Merchan laboratory, new means of targeting tumor and tumor stroma using oncolytic viruses are being explored, including first-in-man treatments based on reengineered vesicular stomatitis virus, for which Phase I trials are planned in head and neck cancer.

Divisional researchers have also explored new epigenetic approaches. Rakesh Singal, MD, has discovered that methylation of the GADD45 alpha gene plays an important role in sensitivity to docetaxel in prostate cancer. A Phase I/II clinical trial to examine whether a demethylating agent azacitidine could reverse resistance to docetaxel in prostate cancer patients is underway.

Judith Deleo Hurley, MD, studies the genetic risk of breast and ovarian cancer in Bahamian women and women of Afro-Caribbean origin in an effort to understand the reasons underlying the predisposition of such women to aggressive locally advanced breast cancers. Her discoveries have led to a Caribbean Women’s Cancer Initiative, supported by the National Cancer Institute (NCI) as well as the Komen Foundation.

Jonathan Trent, MD, and Breelyn Wilky, MD, have developed a state-of-the-art sarcoma center which offers over 15 sarcoma clinical trials. The University of Miami has become the premier sarcoma center in the Southeastern United States, and the number of sarcoma patients seen annually has increased from 54 in 2011 to over 300 in 2015.

the Stem Cell Transplant Center The Stem Cell Transplant Program under the leadership of Krishna Komanduri, MD, has continued to develop rapidly. The number of stem cell transplants has risen from a total of 48 in 2009, to over 160 transplants projected in 2015. The Stem Cell Transplant Unit at Sylvester is introducing the first adoptive CAR-T cell D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Professors Yeon Soong Ahn, MD Bach Ardalan, MD Pasquale Benedetto, MD John Byrnes, MD Lynn Feun, MD Krishna Komanduri, MD Marc Lippman, MD Izidore Lossos, MD Stephen Nimer, MD Stephen Richman, MD Joyce Slingerland, MD Jonathan Trent, MD, PhD Professors of Clinical Medicine Judith DeLeo, MD Mohammad Jahanzeb, MD Charles Vogel, MD Associate Professors Ram Agarwal, MD Dorraya El-Ashry, PhD Jaime Merchan, MD Abdul Mian, PhD Rakesh Singal, MD Donald Temple, MD Associate Professors of Clinical Medicine Mark Goodman, MD Chukwuemeka Ikpeazu,MD Juan Ramos, MD Jonathan Schatz, MD Catherine Welsh, MD Assistant Professors Marzenna Blonska, PhD Aruna Mani, MD Ronan Swords, MD, PhD Justin Watts, MD Breelyn Wilky, MD

Assistant Professors of Clinical Medicine Nicolas Acquavella, MD Timothy Aliff, MD Ney Alves, MD Sharhabil Ammus, MD Carmen Calfa, MD Roberto Cano, MD Vy Dinh, MD Gustavo Fernandez, MD Deborah Glick, MD Thomas Harrington, MD James Hoffman, MD Lazaros Lekakis, MD Reshma Mahtani, DO Raja Mudad, MD Lawrence Negret, MD Denise Pereira, MD Alejandra Perez, MD Agustin Pimentel, MD Maria Restrepo, MD Pearl Seo, MD Alexandra Stefanovic, MD Frances Valdes-Albini, MD Steven Weiss, MD Israel Wiznitzer, MD Research Professors Niramol Savaraj, MD Arthur Zelent, PhD Research Associate Professors Wenche Jy, PhD Seung-Uon Shin, PhD Eric Wieder, PhD Research Assistant Professors Cara Benjamin, PhD Alexey Berezhnoy, PhD Xiaoyu Jiang, PhD Subbarayan Pochi, PhD Ye Xu, PhD Yu Zhang, PhD

trials in the region, which will target relapsed acute lymphoblastic leukemia, diffuse large B cell lymphoma, and mantle cell lymphoma under direction of Drs. Krishna Komanduri and Lazaro Lekakis.

The Division continues to be the premier provider of state-of-the-art multidisciplinary care in the region, and it is poised to lead the charge into the upcoming era of precision and personalized medicine. These efforts serve the highly diverse and unique South Florida population.

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Division of Hepatology Transplantation improves treatment options for liver disease The Division of Hepatology is active in all critical aspects of care for adult patients with liver disease. The team of physicians at the University of Miami work diligently to evaluate and care for patients undergoing liver transplantation, while skilled researchers investigate cutting edge therapies that are dramatically improving treatment options for patients with liver disease.

PROVIDING NECESSARY HEPATOLOGY INPATIENT AND OUTPATIENT SERVICES The Division has a very active clinical program which provides inpatient and outpatient care at all sites on the Medical Center Campus and allows faculty to perform necessary endoscopic procedures on patients.

The various clinics offer inpatient consultative services at every location on the medical campus, including Jackson Memorial Hospital (JMH), University of Miami Hospital (UMH) and the Veterans Administration (VA), whereas faculty practices are located at UMH and University of Miami Hospital and Clinics (UMHC). While the VA offers inpatient and outpatient

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care to veterans with liver disease, the faculty runs the general hepatology clinic at JMH where pre- and posttransplant facilities are located.

FELLOWSHIP PROGRAM IS A NATIONAL DESTINATION TO INCORPORATE HEPATOLOGY TRAINING Since the Division is involved in the education of medical students, residents and gastroenterology fellows, it has an accredited one-year hepatology fellowship for trainees who have already completed gastroenterology. Graduates of this program usually go on to occupy academic faculty positions. Additionally, the Division is one of 12 programs nationally to offer third year gastroenterology fellows the opportunity to incorporate hepatology training into their education, making them eligible to take the American Board of Internal Medicine (ABIM) certifying examinations in both gastroenterology and hepatology.

Below: Dr. Cynthia Levy, Associate Professor of Medicine, explains cholestatic liver disease to a patient.

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Division FACULTY LIST

EXPANDING SERVICES AND EXPERTISE WITH THE ADDITION OF KEY MEMBERS The Division is delighted to announce the expansion of its clinical services with the recruitment of Patricia Jones, MD from the University of North Carolina. Dr. Jones will lead the emerging program in hepatocellular carcinoma in collaboration with the Sylvester Cancer Center. She will also work with Erin Kobetz, MD to address healthcare disparities. A warm welcome was also granted to Lavinia Goldstein, PA, as well as two graduating hepatology

Paul Martin, MD​ Division Chief Professor of Medicine

Professors of Medicine Lennox J. Jeffers, MD Paul Martin, MD Christopher B. O’Brien, MD Eugene R. Schiff, MD Associate Professors Cynthia Levy, MD

Assistant Professors Leopoldo B. Arosemena, MD Kaylan R. Bhamidimarri, MD, MPH Maria D. Hernandez, MD Patricia D. Jones, MD, MSCR Eric F. Martin, MD

Dr. Kaylan Bhamidimarri listens to patient history.

fellows, Eric Martin, MD, and Leo Arosemena, MD, who recently joined the faculty. By contributing their professional expertise, these new Division members provide a critical service to the ever-growing Miami Transplant Institute and ensure the Division continues to lead the nation in adult hepatology.

NOVEL CLINICAL TRIALS UNDERWAY In addition to a robust clinical practice, the Division is also involved in a variety of multicenter and investigatorinitiated clinical trials.

Christopher O’Brien, MD has initiated a novel program exploring the therapeutic use of PreImplantation Factor as a new immune modulator in autoimmune liver diseases and organ transplants.

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This new treatment has the potential to increase the effectiveness of therapeutic immune suppression while lessening patient dependence on currently available, but frequently toxic, therapies.

Cynthia Levy, MD has a portfolio of novel compounds currently in the clinical trial stage to treat cholestatic liver diseases, including Primary Sclerosing Cholangitis.

In addition, Dr. Levy is leading a number of clinical trials that utilize newly developed drugs to reverse fibrosis in liver disease.

Ram Bhamidimarri, MD has emerged as a leader in the management of advanced cirrhosis as well as hepatitis C infection in liver and kidney transplant recipients.

He has also developed protocols to treat hepatitis C in patients with advanced renal disease.

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Division of Hospital Medicine Transforming lives daily Hospitalists function as primary care physicians when a patient is first admitted to the hospital. By creating the initial plan of care and coordinating with specialists, a Hospitalist prepares a patient’s safe discharge and ensures all who are treated receive the highest quality care with superior outcomes.

The faculty of the Division of Hospital Medicine are recognized as leaders in Hospital Medicine education.

Locally, the faculty excel in the Internal Medicine Residency program at Jackson Memorial Hospital with Joshua Lenchus, DO, RPh, FACP, SFHM and Jessica Zuleta, MD, FHM as Associate Program Directors. In addition, Juan Reyes, MD was appointed Associate Director of the Internal Medicine Clerkship for thirdyear medical students. Nationally, the Division is a leader at publishing information regarding its three main pillars: quality improvement and patient safety, medical education, and perioperative medicine.

The Division is also committed to service and leadership. Faculty members serve on national editorial boards, as well as review a number of medical journals.

Additionally, they work with multiple committees and hold leadership roles within the Society of Hospital Medicine, American College of Physicians, and Society of General Internal Medicine. One example is Dr. Lenchus, who is currently serving as the President of the Medical Staff at Jackson Memorial Hospital. Dr. Zuleta is the Chairman of the Pharmacy and Therapeutics Committee at the University of Miami Hospital, while Efren Manjarrez, MD, SFHM is a past Chairman of Medical Peer Review Committee.

Important Roles for Division Chief While Dr. Manjarrez served as the Associate Chief Medical Officer at the University of Miami Hospital, he focused on patient safety and medical peer review.

Most notably, he served as the Course Director for the Society of Hospital Medicine Annual Meeting in March 2015 in Washington, DC, the flagship meeting for America’s 44,000 hospitalists. Dr. Manjarrez is also part of a national task force that seeks to discover the key to optimal control of diabetes in hospitalized and medically unstable patients. This investigation was recognized as “Innovation of the Year” at the recent Society of Hospital Medicine Annual Meeting.

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The University of Miami Hospital: The Division’s Flagship Practice At the University of Miami Hospital (UMH), the Division provides coverage to two academic teaching teams and two faculty direct non-teaching services that specialize in the co-management of Cardiology/Cardiothoracic surgery patients and complex Hematology-Oncology patients.

The Division’s quality metrics, as set by the Center for Medicare and Medicaid Services (CMS) and The Joint Commission (TJC), are near 100%. By providing an internal medicine consult and nocturnist service, the Division ensures there is a continuous presence of faculty at night to provide seamless patient care.

Novel Bedside Procedure Most Popular Rotation in Internal Medicine Residency At Jackson Memorial Hospital, the Division provides an Internal Medicine Consult as well as a novel Bedside Procedure Service. The Consult Service is a teaching program that provides around-the-clock advice to surgical patients with medical diagnoses, while the Division’s Bedside Procedure Service remains the most popular rotation in the Internal Medicine Residency. Initially created by Dr. Lenchus, this exceptional Bedside Procedure Service has received more than $2 million in grants.

Among the Nation’s Best Preoperative Care Another unique program is the University of Miami Preoperative Assessment Center (UPAC). One of the few such centers of its kind, UPAC patients receive a combined Internal Medicine and Anesthesia preoperative risk assessment prior to surgery. The Division of Hospital Medicine also contributes to the nation’s foremost eye hospital, the Bascom Palmer Preoperative Assessment Clinic, by having hospitalists oversee a preoperative clinic staffed by nurse practitioners and physician assistants to evaluate low-to moderate-risk medical patients.

Teaching the Teacher Dr. Zuleta’s passion for medical education inspires her to teach physicians how to be excellent clinical instructors to their future students. To this end, she leads the Division of Hospital Medicine’s Faculty Development Series, which is specifically designed for junior faculty.

As Dr. Zuleta guides senior medical educators on how to teach the younger generation of faculty hospitalists, U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Division FACULTY LIST Efren Manjarrez, MD, SFHM Interim Division Chief Assistant Professor of Clinical Medicine

Professors Steven Cohn, MD, FACP, SFHM Medical Director, UHealth Preoperative Assessment Center (UPAC) Medical Director, UMH Medical Consultation Service, Barry Materson, MD, MBA Academic Mentor, Hospital Medicine

she educates them on how to perform a physical exam and how to question patients in a non-threatening manner. So far the results of this development series are promising, and teaching scores are up for junior faculty. As a bonus, learner satisfaction is also on the rise.

A $2 Million Grant for Patient Safety Dr. Lenchus began his novel procedure-based instruction in 2007. With nearly 10,000 procedures performed since, he has written about how to create a curriculum with clinical and educational outcomes. His results for safety are impressive, with more than a 90% success rate. Since patient safety complications can cost a hospital between $25,000 and $50,000, Dr. Lenchus’ manuscripts represent a savings of millions of dollars for the institution.

In other news, Dr. Lenchus was awarded multiple grants by the Florida Medical Malpractice Joint Underwriting Association through 2018 to study the effects of simulation-based procedural education on reducing thoracentesis-induced iatrogenic pneumothorax rates. Additionally, Dr. Lenchus will lead the Procedures Pre-Course at the Society of Hospital Medicine Annual Meeting in San Diego in March 2016.

Hospital Medicine Highlights In alignment with the American Board of Internal Medicine’s campaign of “Choosing Wisely,” Steven Cohn, MD, always asks before automatically testing for perioperative blood clotting. Studies show that although this kind of testing has become routine, it rarely has a clinical impact on perioperative bleeding outcomes. In fact, less than 1% of the time does testing lead to a change in the perioperative management of bleeding risk.

Dr. Cohn has found that unless the history and physical exam identify risk factors for abnormal bleeding, D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Associate Professors Joshua Lenchus, DO, RPH, FACP, SFHM President, Jackson Health System Medical Staff Associate Program Director, Jackson Memorial Hospital Internal Medicine Residency Associate Director, UM-JMH Center for Patient Safety

Assistant Professors Syeda Uzma Abbas, MD, MPH Medical Director, University of Miami Hospital Alan Briones, MD Jorge Florindez, MD German Giese, MD Matthew Imm, MD Ashwin Mehta, MD, MPH Medical Director, Integrative Medicine Shreevinaya Menon, DO Deepak Mummidavarapu, MD Rene Parraga-Montilla, MD Sub Internship Clerkship Director at University of Miami Hospital, Hospital Medicine Aldo Pavon Canseco, MD Medical Director, Bascom Palmer Sarahi Rodriguez-Perez, MD Jessica Zuleta, MD, FHM Education Director, Hospital Medicine Associate Program Director, Jackson Memorial Hospital Internal Medicine Residency

the test should not be administered to a patient. This saves time, effort and money for both the hospital and most importantly, for the patient.

As for blood glucose control measures, Dr. Manjarrez and his colleagues across the country are interested in finding the “sweet spot” where medical centers can best control blood glucose levels in hospitalized patients.

Finding this balance is important because high and low blood glucose levels increases costs, length of hospital stay, and mortality, especially in surgical patients.

Guidelines on glycemic control are clear in the hospital, whether in ICU or on a medical-surgical floor; however, it is still uncertain how multidisciplinary teams can work together to prevent patients from experiencing uneven and dangerous blood glucose levels.

After reviewing data from 100 hospitals across the country, Dr. Manjarrez and his colleagues have identified the secrets. Hospitals need a glycemic control champion with a multidisciplinary committee to own the project, and must institute protocols to guide practitioners. Additionally, one-on-one feedback between medical practitioners must occur in order to help modify the initiative until it integrates seamlessly for physicians and patients alike.

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Division of Infectious Diseases Working at the crossroads of research and patient care The Division of Infectious Diseases specializes in the research and clinical management of viral infections, particularly HIV-1 and Hepatitis C. To this end, many faculty members serve in leadership roles in a variety of UM programs that enhance and coordinate AIDS-related research activities. These programs include the newly established UM AIDS Institute, as well as the University of Miami Center for AIDS Research (CFAR), which is one of 20 National Institute of Health (NIH)-funded CFARs in the country and the only one in Florida. The UM AIDS Institute serves as the umbrella under which all AIDS-related basic and clinical research, philanthropy and outreach are coordinated. Both the CFAR and AIDS Institute generate pilot program funding which help grow promising research projects and ensure they better compete for additional funding.

HIV/AIDS Research and Treatment Divisional faculty are engaged in several key areas of research. These include a variety of strategies for the cure of HIV infection, the use of pre-exposure prophylaxis, as well as educating women and children who live with HIV-1 about the importance of adhering to an antiviral regiment.

Several faculty members research HIV/AIDS associated opportunistic infections including Hepatitis C and tuberculosis, and promote strong outreach and education efforts to combat the spread of these illnesses.

These academic physicians also have key roles in antimicrobial stewardship and infection control programs that are central to ensuring quality care and better outcomes at UM and Jackson Hospital Systems. Several members of the Division’s faculty work with the Miami Transplant Institute (MTI) to develop protocols that better prevent and manage infections in immunocompromised individuals. These activities also provide an opportunity for research. The Division has taken a proactive role in preparation for the threat of emerging tropical infectious diseases, such as Dengue and Chikungunya, in the Central and South American region, and has established fellowship exchange programs with Sao Paulo, Brazil; Cali, Colombia and Ciudad de Guatemala, Guatemala. These exchange initiatives provide excellent opportunities for fellows to gain expertise in the clinical management of tropical infectious diseases.

Miami is at the epicenter of the HIV/AIDS epidemic and its location as the “Gateway to the Americas” puts it 22

on the frontlines in the fight against emerging infectious diseases such as Dengue and Chikungunya. Research within the Division aims to develop an effective response to the threat of HIV and associated morbidities such as Hepatitis C virus. In addition, faculty physicians direct a broad spectrum of research projects with a strong track record of extramural funding.

Susanne Doblecki-Lewis, MD is studying how to enhance linkage to pre-exposure prophylaxis in high risk individuals, while Margaret Fischl, MD directs AIDS Clinical Trials Group efforts within the Division and focuses her research on HIV in women. Also working closely with the female population, Maria Alcaide, MD has been examining how vaginal interactions influence the risk of HIV acquisition. Isabella Rosa-Cunha, MD has been investigating the root cause of a recent increase in anal cancers in HIV-infected individuals. Studying patients on antiretroviral therapy, Mario Stevenson, PhD is developing novel agents that harness the antiviral properties of host defense proteins such as Apobec 3G and is identifying how HIV persists in the human body. In order to improve the quality of care for people living with AIDS, Allan Rodriguez, MD assists in the development of novel strategies to advance treatment adherence. Several physicians, including Lilian Abbo, MD and Thomas

Drs. Susanne Doblecki-Lewis and Paola Lichtenberger assessing case report with one of the fellows.

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Division FACULTY LIST Mario Stevenson, PhD Division Chief Director, AIDS Institute Co-Director of CFAR Professor of Medicine

Dr. Allan Rodriguez discussing outreach strategies with staff and colleagues.

Hooton, MD have a strong research interest in hospitalacquired infections, while others, such as Michele Morris, MD and Jacques Simkins-Cohen, MD are interested in transplant-related infections that sometimes develop in an immune-compromised host. Research projects undertaken by the Division are supported by Research Units that coordinate recruitment of subjects for these kinds of investigative studies. Dushyantha Jayaweera, MD and Rafael Campo, MD provide clinical expertise for the management of individuals living with HCV infections and HCV/HIV co-infections.

Improving Patient Safety Lilian Abbo, MD is the UHealth Associate Chief for Patient Safety and Quality. In this capacity, she leads several multidisciplinary initiatives to improve patient safety across a variety of healthcare systems. Among these initiatives, Dr. Abbo leads the bedside patient safety walking rounds at UMH and UMHC/Sylvester on a biweekly basis. Dr Abbo is also a core faculty member of the Infectious Diseases Immunocompromised Host Service, and is the Director of the Antimicrobial Stewardship Programs for Jackson Memorial Hospital and UHealth.

In addition, she has served as President of the Miller School’s Women in Academic Medicine (WIAM) group since 2014.

Educating the Next Generation The Division of Infectious Diseases is committed to the training and development of the next generation of Infectious Disease specialists. The Fellowship Program is spearheaded by Program Director Susanne DobleckiLewis, MD and Associate Program Director, Paola Lichtenberger, MD. The mission of the program is to improve the diagnosis, treatment, and prevention of infectious diseases throughout South Florida, Latin America and the Caribbean region. Graduates go on to occupy a variety of leadership positions in the clinical, academic and public health arenas throughout the region.

The Division hosts five concurrent inpatient infectious D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Professors of Medicine Rafael Campo, MD Gordon Dickinson, MD Margaret Fischl, MD Thomas Hooton, MD Dushyantha Jayaweera, MD Michael Kolber, MD Allan Rodriguez, MD Associate Professors Lilian Abbo, MD Maria Alcaide, MD Gio Baracco, MD Catherine Boulanger, MD Jose Castro, MD Luis Espinoza, MD

Michele Morris, MD Isabella Rosa-Cunha, MD Stephen Symes, MD Assistant Professors Hector Bolivar, MD Jose Camargo, MD Susanne Doblecki-Lewis, MD Paola Lichtenberger, MD Alexis Powell, MD Antoine Salloum, MD Jacques Simkins-Cohen, MD Research Assistant Professor Mark Sharkey, PhD

diseases teaching services, including a dedicated transplant/immunocompromised host service. Fellows may pursue specialty tracks in HIV and HCV, infections in immunocompromised hosts, tropical medicine / global health, and hospital epidemiology and infection control.

The Fellowship Program provides trainees with a comprehensive clinical and academic experience.

During the program, fellows may work in inpatient and outpatient settings at private, public, and federal government facilities, making them adept at managing a wide variety of patient populations and pathology.

Fellowship Program trainees also learn how to investigate and address health disparities, as well as the importance of educating the community at large about infectious diseases. All fellows are encouraged to develop a mentor relationship with faculty that helps set them on a career as an academic physician. They are also encouraged to share their knowledge in the form of numerous presentations at national meetings, becoming eligible for Infectious Diseases Society of America scholarship awards, and publishing their findings in a variety of medical publications annually. Fellows develop excellent academic, educational, and leadership skills which are invaluable assets in any professional or clinical setting.

Michael Kolber, MD, PhD, is leading the Southeast AIDS Education and Training Center (SE AETC) education effort in South Florida and is focused on improving HIV education for providers, as well as moving clinics toward practice transformation to improve care outcomes.

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Division of Nephrology and Hypertension Enhancing patients’ health through excellence The Division of Nephrology and Hypertension’s mission is to enhance the health of patients who are suffering from kidney disease by offering excellence in clinical medicine, research and postgraduate training.

Seventeen full-time and three voluntary faculty members provide clinical care for all nephrology-related ailments at the University of Miami Hospital and Clinics, Jackson Memorial Hospital, and the Miami Veterans Affairs Medical Center, as well as the various outpatient facilities on campus. Faculty members also assist patients at UHealth at Kendall and in community-based dialysis clinics throughout the area. During the past fiscal year, physicians rendered care to more than 1,100 new patients and provided 7,500 follow-up visits at outpatient clinics.

At UM hospitals, physicians provided more than 1,900 consultations and conducted 14,000 follow-up inpatient encounters, while dedicated staff cared for more than 430 outpatient dialysis patients and oversaw more than 4,000 inpatient dialysis treatments.

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The Miami Transplant Institute, A National Leader Four physicians staff the Miami Transplant Institute (MTI), one of the nation’s busiest and most recognized centers for excellence in kidney transplantation. Operated collaboratively between Jackson Memorial Hospital and the University of Miami Miller School of Medicine, the MTI provided transplantation preparation and care to more than 300 patients who received kidney or kidney/ pancreas transplantations in 2014.

Having established itself as the number one kidney transplant center in 2014, the MTI continues to provide outstanding quality of service. By maintaining high standards for patient care and treatment, the MTI hopes to retain its designation as the best kidney transplant center in the United States. Due to the international recognition the center has achieved, patients from all over the world struggling with proteinuric kidney diseases travel to the MTI seeking experimental treatment

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Division FACULTY LIST

strategies before and after their kidney transplant. The paired living donor exchange transplantation program has grown in the past year, with 11 patients having received a transplant in 2014 using this method. A paired kidney exchange occurs when two or more donor/recipient pairs are not compatible with each other within the pair, but remain compatible across pairs. In addition, Adela Mattiazzi, MD and colleagues have refined the treatment and care of highly sensitized recipients, leading to successful transplantations in this otherwise difficult-totreat patient group.

South Florida’s only academic Interventional Nephrology Program The Division of Nephrology and Hypertension’s Interventional Nephrology suite is South Florida’s only academic Interventional Nephrology program. In addition to supporting a vibrant, NIH-funded research program, Interventional Nephrology also provides comprehensive vascular access care to dialysis patients and trains physicians in endovascular procedures.

Offering advanced training in transplantation and interventional nephrology, the fellowship training program attracts highly qualified candidates from throughout the country. In addition, this program provides in-depth clinical education in general nephrology.

Similar to years past, five fellows successfully graduated from the program and are now expertly trained and educated to impact the lives of nephrology patients throughout the country.

The Division’s research Mission is growing stronger every year The faculty have been highly successful in securing external funding from both private and federal sources, enabling them to contribute to the scientific body of knowledge with more than 30 peer-reviewed publications in the last year. A number of these articles and publications have appeared in the nation’s most prestigious scientific journals.

Opposite page: Dr. Alessia Fornoni reviewing histological picture

Oliver Lenz, MD, MBA Interim Division Chief Professor of Clinical Medicine

Professors of Medicine Alessia Fornoni, MD, PhD Director, Peggy and Harold Katz Family Drug Discovery Center Leopoldo Raij, MD David Roth, MD Clinical Director Professors of Clinical Medicine Gabriel Contreras, MD, MPH Loay Salman, MD Kupin Warren, MD

Research Associate Professors Christian Faul, PhD Sandra Merscher, PhD Assistant Professors of Clinical Medicine Marco Ladino Avellaneda, MD Christian Faul, PhD Adela Mattiazzi, MD Jair Munoz Mendoza, MD Sandra Merscher, PhD Fernando Pedraza, MD

Associate Professors of Clinical Medicine Jorge Diego, MD Dollie Green, MD Giselle Guerra, MD Ali Nayer, MD Ivonne Schulman, MD

Below are just a few of the outstanding faculty members who have contributed to the scientific mission.

Sandra Merscher, PhD, co-authored a paper on novel pathways ameliorating chronic kidney disease that may be targeted by drugs (Nature Medicine 21:601-609, 2015).

Jair Munoz-Mendoza, MD, described an important pilot study on how the composition of the dialysate, which is used to treat patients with end-stage kidney failure, can affect relevant health outcomes (American Journal of Kidney Diseases, e-publication ahead of print). Alessia Fornoni, MD, PhD, authored a high impact review on how lipids play an important part in key cells of the kidney (Nature Review Nephrology 10:379-388, 2014). Gabriel Contreras, MD, MPH, has made it possible for patients in South Florida suffering from lupus nephritis or high blood pressure to enroll in important, multi-center clinical trials.

Building on the accomplishments of the past academic year, the Division of Nephrology and Hypertension is looking forward to further strengthening its research mission, while maintaining the gold standard of excellence in both patient care and teaching.

of normal and diseased glomeruli with faculty and staff at the Katz Center.

From left to right: Marianne Pons, PhD, Dr. Alessia Fornoni, Sandra Merscher, PhD, Javier Varona Santos, PhD and Patricia Wahl, PhD.

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Division of Population Health and Computational Medicine At the crosshairs of a new discipline in healthcare delivery The Division of Population Health and Computational Medicine is the latest addition to the suite of specializations offered at the Department of Medicine.

Striving to improve the health and wellness of the diverse South Florida population, the Division is made up of faculty and staff who are dedicated to harnessing clinical computer systems and the data contained within. The Division’s activities occur in the space where technology, “Big Data” analytics and clinical care intersect. It is through the integration of these seemingly disparate disciplines that the faculty will advance the Division’s mission of research, education and service.

The creation of the Division of Population Health and Computational Medicine could not have occurred at a better time, as the nation’s health care delivery model is currently undergoing significant changes. This new conceptualization towards Population Health changes the emphasis of healthcare from visit volumes and preformed procedures to the value and quality of care delivered to patients.

This shift from volume to value is based on the ability to obtain usable information within a clearly defined context. By having large amounts of data available to them quickly, clinicians can more effectively manage both acute and chronic illness. The ability to mine data and specifically tailor analytic systems continues to be perfected. These exciting new capabilities mean that the healthcare system can now evolve past merely managing disease to predicting it and eventually altering the trajectory of a patient’s health by avoiding acute illness episodes altogether. By defining and studying the concepts of Population Health, the Division can then translate these findings into practical application. The Division has outlined three major areas of emphasis for 2015-2016: 1) Develop a 360-degree view of the patient 2) Build a medical center without walls 3) Create the framework for predictive medicine

such as access to health care and adherence to medical recommendations. Social Determinants of Health include access to transportation, a patient’s education level, and societal perceptions of health care practices and health literacy. The combination of standard clinical metrics with these non-traditional variables provides the 360-degree view of patient populations necessary to develop effective care strategies. This whole-patient approach also serves to tailor interventions so that each population can optimize its own health and wellness standards.

To meet this important goal, the Division has begun defining the types of Social Determinants of Health required. Once defined, a systematic collection of this data will take place across the University of Miami Health System within the Enterprise Clinical Data Warehouse.

After the data is collected, the Division will integrate it into various enterprise clinical processes and computer systems. These foundational steps will ensure that data capturing the Social Determinants of Health becomes an important component when crafting care plans for the patient populations served.

A MEDICAL CENTER WITHOUT WALLS Clinicians today have a fragmented view of their patients’ overall health. Health data is usually collected during a face-to-face encounter or when undergoing diagnostic testing, which means the information it yields is not integrated into the larger context of the patient’s overall health. In order to manage chronic disease or better predict acute illness, this health data should be collected more frequently and over a longer span of time. To further

Dr. Erin Kobetz works with a diverse group of patients across the University of Miami and the Miami metropolitan area to address issues of health disparity – particularly when it comes to cancer. She is pictured here in Little Haiti, the

360-VIEW OF THE PATIENT The health outcomes of patient populations are profoundly affected by social and culture factors outside of traditional physical and chemical metrics such as blood pressure and cholesterol readings. These social and cultural factors, called Social Determinants of Health, affect a patient’s well-being by influencing critical health-related processes 26

largest Haitian settlement in the United States, where she has collaborated with community leaders for the past two years. Dr. Kobetz’s leadership will be instrumental as the Division collects data and integrates the application of social and cultural information into various clinical processes and systems.

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Division FACULTY LIST David M. Seo, MD Division Chief Associate Vice President IT for Clinical Applications Chief Medical Information Officer Chief Research Information Officer

Above: Drs. Ana Palacio and Leonardo Tamariz have substantial experience in the analysis of “big data” repositories to determine the effects of clinical interventions on health outcomes. They are pictured here at their Research Methods course for House Staff, where students learn how to complete an original research study under the guidance of a mentor. Additionally, Drs. Palacio and Tamariz will develop programs to train the next generation of physicians on population health and computational medicine.

Associate Professor Erin Kobetz, PhD, MPH Department of Medicine Associate Director, Disparities and Community Outreach Sylvester Comprehensive Cancer Center Senior Associate Dean for Health Disparity

Associate Professors of Clinical Medicine Ana Palacio, MD, MPH Department of Medicine Co-Director, Resident Scholarly Activity Program (RSAP) Leonardo Tamariz, MD, MPH Department of Medicine Director, Resident Scholarly Activity Program (RSAP) Chief of the Miami VA Institutional Review Board

Left: The University of Miami IT Clinical Applications group has developed a robust data environment consisting of clinical systems, Enterprise Clinical Data Warehouse and the Hadoop Population Analytics Platform. The data environment includes tools for obtaining information from food diaries, activity and blood pressure monitors.

It also provides alerts and analytics of electronic medical records via email or messaging systems. The Division has partnered with the UM IT Clinical Applications group to help integrate business processes and scholarly activity, as well as harness these tools to improve patient health.

complicate matters, current health data does not provide an effective patient-centered feedback loop that engages the patient in their own health. Internet-connected devices like scales, blood pressure and blood glucose monitors, have the ability to autonomously send health data to the electronic health record, if the patient authorizes it.

By having access to this data, patients often feel more control and ownership over their health care and are more likely to embrace the development of better educational materials and health tools. To meet this critical goal, the Division is coordinating programs that utilize Internetconnected devices such as activity trackers and blood pressure cuffs that send health data directly to Electronic Health Records. The Division is also exploring how the data collected can be utilized to develop novel interventions.

PREDICTIVE MEDICINE For high-quality health care to be cost effective, disease management will need to be accompanied by disease D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

prediction. According to data from the Agency for Healthcare Research and Quality, two-thirds of patients who suffer a major acute illness on an annual basis were healthy in the prior 12 months. This means that in order to seriously impact health, disease management must be accompanied by disease prediction and intervention.

The University of Miami IT Clinical Applications group is in the midst of developing a robust and comprehensive Enterprise Clinical Data Warehouse and Hadoop Population Analytics Platform. The Enterprise Clinical Data Warehouse contains clinical, scheduling, financial and very soon, data regarding Social Determinants of Health. The Division is assisting the Clinical Applications group in defining and validating what data needs to be stored in the warehouse.

Partnerships have also been created with the Clinical Applications group to harness the Hadoop Population Analytics Platform and develop algorithms for disease prediction in patient populations.

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Division of Pulmonary, Allergy, Critical Care and Sleep Medicine Comprehensive clinical services and research undertakings The Division of Pulmonary, Allergy, Critical Care and Sleep Medicine offers a full portfolio of clinical services and research investigations that have garnered national and international recognition. The Division’s inpatient clinical activity was incredibly robust during Fiscal Year 2015, when more than 17,657 inpatient visits were conducted. In addition, the Division runs two fellowship programs under the direction of Horst J. Baier, MD, David De La Zerda, MD, and Andrew Quartin, MD. Together, these programs train a total of 17 fellows to become specialists in pulmonary and critical care medicine.

Cystic Fibrosis (CF) and Non-Cystic Fibrosis Bronchiectasis Led by Andreas Schmid, MD and Matthias Salathe, MD, the Pulmonary Division offers specialized care to adult patients with cystic fibrosis and patients suffering from bronchiectasis not associated with CF. The CF adult specialty is served by a strong clinical research team, which allows patients to reap the benefits of new drug developments by extending them an invitation to participate in national and international pharmaceutical studies. Additionally, a basic and translational science program accredited by the Cystic Fibrosis Foundation seeks to find therapies for the lung disease of CF patients.

Dr. Salathe is a member of the Center Committee and the Therapeutics Development Network Steering Committee of the Cystic Fibrosis Foundation.

Allergy/Immunology Led by Lauren Fine, MD, the Division’s Allergy Program has mentored and educated countless undergraduate students, as well as internal medicine, ear, nose and throat, and pulmonary residents about the intricacies of allergic reaction and specific treatment options.

Dr. Fine, who was recently granted an appointment to the Journal of Asthma editorial board, precepts students during their first and second years at Jackson Memorial Hospital.

Additionally, she spends several semesters with MD/MPh degree seeking students as a Problem-Based Learning (PBL) leader and teaches them allergy/ immunology specific training.

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Pulmonary Hypertension Program The University of Miami Pulmonary Hypertension Program takes an interdisciplinary approach to this condition and integrates concepts learned in the management of pulmonary, cardiology, rheumatology, hepatology, and radiology, as well as complications experienced during heart and lung transplantations.

Under the expert direction of Shirin Shafazand, MD and David De La Zerda, MD, patients from all across South Florida come to the University of Miami for the management of this complex and life-threatening disease.

The pulmonary hypertension clinics offer state-of-the-art treatments including oral and intravenous therapies, and often participate in the clinical trial stage of cutting edge therapies.

Sleep Center The high-tech University of Miami Sleep Center, located on the fifth floor of the Bascom Palmer Eye Institute, performed over 4,700 clinical visits and conducted 2,400 sleep studies in Fiscal Year 2015. The Center also helps train future sleep physicians by annually providing three positions in the Accreditation Council for Graduate Medical Education (ACGME)-Accredited Sleep Fellowship.

To date, participation in this fellowship program correlates with a 100% passing rate on the Sleep Medicine Boards. Additionally, a variety of educational activities are provided at the Sleep Center, including a Yearly Sleep Continuing Medical Education (CME) Symposium where physicians come from across the country to enhance their knowledge of sleep medicine. Throughout the years, the Sleep Center has engaged in multiple research projects, many of which have been published in internationallyrecognized journals, and presented at the annual National Sleep Medicine conference.

Thoracic Oncology Program Elio Donna, MD and Gregory Holt, MD, are part of a multidisciplinary team that meets weekly for case presentations and discussion on the management of the current patient population. The team recently grew with the addition of Sixto Arias, MD, an interventional pulmonologist who brings advanced therapeutic options to U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Division FACULTY LIST

Left: Dr. Matthias Salathe next to the Vitrocell VC-10 smoking robot used to expose cells to cigarette smoke or

Matthias A. Salathe, MD​ Division Chief, Vice Chair for Research Director, Cystic Fibrosis Center Director, UM Adult Clinical Translational Research Site Sertel Chair in Pulmonary Diseases Professor of Medicine

e-cigarette vapor..

patients in South Florida suffering from lung cancer.

Team members work in close collaboration with a diverse mix of medical professionals to prescribe an effective treatment strategy and help detect pulmonary lung nodules as quickly and efficiently as possible.

Interstitial Lung Disease Marilyn K. Glassberg, MD, who serves as the Director of the Interstitial Lung Disease Program, is a recognized leader in interstitial lung disease (ILD). She has successfully conducted numerous multi-center trials in Idiopathic Pulmonary Fibrosis (IPF) over the last decade, and has led one of the National Institute of Health’s (NIH) IPFnet Centers of Excellence since 2008. The University’s Center has also become a national leader in the application of stem cell treatments in patients with IPF in Phase I/Phase II trials approved by the Food and Drug Administration (FDA).

Alpha-1 Antitrypsin Deficiency (AATD) Program The Alpha-1 Program at the Division provides specialized patient care for those diagnosed or suspected of having alpha-1 antitrypsin deficiency (AATD), a genetic condition that predisposes individuals to liver and lung diseases such as chronic obstructive pulmonary disease (COPD), emphysema, and bronchitis. This program, led by Michael Campos, MD and Adam Wanner, MD, works closely with the Alpha-1 Foundation to share common goals and collaborate on novel therapeutic approaches that impact affected individuals.

Critical Care Medicine Tanira Ferreira, MD, who is the Chief Medical Officer (CMO) at the University of Miami Hospital (UMH), has focused her efforts towards the implementation of evidencebased protocols in critical care units. Her emphasis on quality initiatives will provide better metrics in such areas as patient flow, Hospital Acquired Conditions (HAC) and Patient Safety Indicator (PSI) prevention.

Daniel Kett, MD is Medical Director of Medical D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Professors of Medicine Horst J. Baier, MD, JD​ Marilyn K. Glassberg-Csete, MD Robert M. Jackson, MD Daniel H. Kett, MD​ Andrew A. Quartin, MD​ Matthias A. Salathe, MD​ Roland M. Schein, MD Adam Wanner, MD Associate Professors Michael A. Campos, MD Elio Donna, MD​ Shirin Shafazand, MD

Assistant Professors Alexandre R. Abreu, MD​ Sixto Arias, MD Rafael Calderon, MD David De La Zerda, MD Tanira D. Ferreira, MD Lauren M. Fine, MD Gregory E. Holt, MD, PhD​ Stefanie Krick, MD, PhD Mehdi Mirsaeidi, MD, MPH Andreas Schmid, MD​ Research Assistant Professor Eliana P. Mendes, MD Research Professor (Emeritus) Philip L. Whitney, PhD​

Intensive Care Units at Jackson Memorial Hospital and the Sylvester Comprehensive Cancer Center.

His predominant research interests are invasive fungal infections and intensive care unit infection control. Dr. Kett has obtained research funding from the NIH to study the treatment of multi-drug resistant gram-negative pathogens. He also serves as chair of the University Institutional Review Board.

The Miami Veteran’s Administration (VA) Medical Center’s medical intensive care unit is run by Roland Schein, MD, and Andrew Quartin, MD. Research interests include sepsis, respiratory failure, severe community-acquired pneumonia, and acute kidney injury. Dr. Quartin serves on the Infection Control Committee, and is Chairman of the Cardiopulmonary Resuscitation Committee.

Researching E-Cigarettes A grant to investigate the potential pulmonary health risks of e-cigarettes has been awarded to Matthias A. Salathe, MD by the Florida Department of Health. The $1.95 million dollar grant will be used to prove or discredit the advertised health benefits of e-cigarettes by providing data and analysis on whether e-cigarette vapors are harmful to the human body and its airways. Dr. Salathe’s team will study the chemical compounds of the vapors with a highly sophisticated smoking robot, which exposes human airway cells to e-cigarette vapors. This study will provide the necessary research on whether potential risks are associated with the use of e-cigarettes.

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Division of Rheumatology and Immunology Clinical excellence emerging from research insights The Division of Rheumatology transforms the lives of patients and their families every day with outstanding clinical services, groundbreaking research, and top-notch educational activities.

A provider of clinical rheumatology services, the Division conducted over 13,000 patient encounters this past year, and anticipates double-digit growth in the year ahead. The Division is proud to be the top referral center in South Florida for the most complex and difficult-totreat rheumatology cases.

In addition to providing cutting edge care to patients throughout South Florida, the Division also sees a number of challenging cases referred from locations throughout Latin America and the Caribbean. In order to provide the best care to patients, satellite clinics located in Deerfield Beach, Hialeah, Kendall, and Plantation supplement Rheumatology’s presence on the main Miami medical campus. Patients are also seen at specialty clinics dedicated to: lupus, Mixed Connective Tissue Disease (MCTD), myositis, rheumatoid arthritis, rheumatic lung disease, Sjogren’s syndrome, and vasculitis.

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THE RHEUMATIC LUNG DISEASE CLINIC The rheumatic lung disease clinic, which is run cooperatively by Dana Ascherman, MD of the Division of Rheumatology, and Marilyn Glassberg, MD of the Division of Pulmonary Medicine, showcases the importance of structuring clinics around a single disease process.

The result is that in one visit, patients with complex lung problems related to rheumatic diseases can see two internationally-recognized experts who will then work cooperatively to tailor a strategic care plan for patients from both a rheumatology and pulmonary perspective. This interdisciplinary, patient-focused approach is designed to deliver better outcomes for patients, and has already helped Drs. Ascherman, Glassberg, and their colleagues to make groundbreaking new discoveries regarding the immunology of lung disease seen in some patients with rheumatoid arthritis. These insights, in turn, allow University of Miami doctors to provide better care for patients. Instead of merely reading what has already been written, UM’s physicians are “writing

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the book” from which other doctors will learn more about these specializations within rheumatology.

TRANSFORMATIVE RESEARCH Research transforms the lives of present and future patients by introducing improved diagnostic and treatment approaches to rheumatic diseases. In addition to investigating interstitial lung disease in rheumatoid arthritis as mentioned above, notable studies published this year provided new insights about the initiation of autoimmune responses in polymyositis. Another important study helped distinguish between cases of lupus and MCTD on clinical and immunologic grounds.

Research opportunities in the Division of Rheumatology range from basic molecular biology, cell biology, and immunology to highly patientoriented clinical research projects. The excellent clinical research unit continues to grow thanks to the efforts of coordinator Judith PignacKobinger. The Division is proud to be a nationwide leader in patient participation in a clinical trial of a novel drug therapy for Inclusion Body Myositis. Inclusion Body Myositis is a condition that causes progressive muscle weakness and disability, for which no currently available treatment has been found to be effective. Using cutting edge insights, this study uses an antibody that interacts with muscle cells to promote their growth.

Eric L. Greidinger, MD Division Chief Associate Professor of Medicine

​ rofessor of Clinical Medicine P Carlos J. Lozada, MD Fellowship Program Director Associate Professors Dana P. Ascherman, MD Elaine C. Tozman, MD

Assistant Professors Maria F. Carpintero, MD Schartess Culpepper-Pace, MD Ozlem Pala, MD Christine Savage, MD Larry Young, MD Chief of Rheumatology, VA

EVIDENCE-BASED APPROACH TO EDUCATION The Division’s work in education transforms the lives of all its members through daily interactions with trainees and patients. As physicians teach medicine that is evidence-based, but grounded in compassion, they hope to transform the lives of generations of physicians and their subsequent patients. The Division recognizes the achievement of Larry Young, MD, the inaugural recipient of the University of Miami, Department of Medicine Junior Faculty Teaching Award. Dr. Young serves as Director of Medical Education and Chief of the Division of Rheumatology at affiliated Miami Veterans Affairs Medical Center (VAMC). He is also an integral part of clinical training programs at the Division of Rheumatology, the Department of Medicine, and the Medical School. Even beyond the University, Dr. Young’s knowledge and teaching excellence have led him to be named the co-director of an Evidence-Based Medicine training program held annually at Duke University.

In addition, Dr. Young nurtures great clinical skills in his trainees as a worthy successor to the late Harvey Brown, MD. Dr. Brown, a legendary master clinician and co-founder of the Division of Rheumatology, helped train Dr. Young as well as hundreds of other highly-skilled University of Miami physicians.

Opposite page and above: To assess for improvement in patients in clinical trials for Inclusion Body Myositis, the Rheumatology clinical research group tracks changes in the distance the study subject can walk in six minutes, performs bedside strength testing, and uses Baltimore Therapeutic Equipment (BTE) Evaluator system to quantitatively measure muscle power in a controlled environment.

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Educational Programs Innovations in Education The University of Miami/Jackson Health System Internal Medicine residency program was first accredited by the Accreditation Council for Graduate Medical Education (ACGME) on August 17, 1954, only two years after the University of Miami Medical School welcomed its first class. The residency program has produced internationally renowned faculty, such as Julio Chirinos, MD, Assistant Professor of Medicine in the Division of Cardiology at the University of Pennsylvania and Gilberto Lopes, MD, Senior Consultant in Medical Oncology and Assistant Director for Clinical Research at the Johns Hopkins Singapore International Medical Center. Additionally, the program has educated notable local leaders including Larry Young, Director of Education at the VA and Ernesto Bernal, MD, Division Chief of Endocrinology. Over the past six months, the Internal Medicine Residency underwent a transition in both leadership and organizational focus.

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BLOCK SCHEDULING Since residency training is a patient-centered educational experience, many physicians historically lived in or near the hospital for the duration of their term. In fact, the moniker “house officer” was derived from this practice.

Over the last 125 years however, the face and location of patient care has shifted as the majority of care provided to patients, even in most internal medicine subspecialties, occurs in the ambulatory arena. To accommodate this shift, the residency program began to operate in a block schedule with time set aside for residents to practice in the ambulatory setting.

The University’s program adopted this kind of curriculum earlier this year in a 4+2+2 model. Residents spend four weeks in an inpatient setting, then two weeks in an elective or emergency department, followed by two weeks in continuity practice. This kind of structured

U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

schedule allows for a variety of innovations in education and patient care. Some of these innovations include the opportunity for longitudinal subspecialty outpatient electives, a standardized three-year ambulatory curriculum shared across all practice sites, and a dedicated board review. The recent change in schedule also allows residents to practice their medical home model, which allows time for communication with patients, quality improvement, and panel management with a focus on core clinical outcomes.

PROCEDURAL COMPETENCY ROTATION

GLOBAL HEALTH

In conjunction with the UM/JMH Center for Patient Safety, the Internal Medicine Residency, under the leadership of Joshua Lenchus, MD, began the procedural competency initiative in 2006. The goal of this initiative was to evolve from the flawed “see one, do one, teach one” model of procedural training to a more structured and standardized technique. This method of Bedside Procedure Skills Training has improved patient outcomes, delivering complications rates lower than the national averages for all performed procedures. This initiative has also improved resident confidence and competence.

Since its inception, the program has trained over 1,500 physicians, including all Internal Medicine and Combined Internal Medicine and Pediatrics (Med-Peds) residents, with 80 training programs across 31 states and multiple different countries.

The core of the University of Miami Miller School of Medicine’s mission is improving the health of the community. In Miami-Dade County, the definition of community includes transnational patients both at home and abroad. With UHealth/Miller being part of the international effort to make health care a basic human right, the University offers residency education pathways to provide structured training. Since 2006, the Jay Weiss Internal Medicine Residency pathway has provided funding for an additional year of global health training and a Masters in Public Health. This training was expanded in 2011 and became the Global Health Track under the direction of Toni Eyssallenne, MD, PhD. Those residents with an interest in Global/Public Health now have an opportunity to receive formal training and exposure to multiple disciplines associated with this growing field.

Top left: Residents and students benefit from traditional teaching by Opposite page: Dr. Stefanie Brown, Program Director, Internal Medicine Residency

esteemed faculty member, Dr. Marco Gonzalez.

Program, Vice Chair for Education, Department of Medicine, with associate

Top right: Medicine clerkship students are taught by Drs. Maureen Lowery

program directors.

and Rene Parraga-Montilla utilizing the Harvey simulator in the Gordon

From left to right: Dr. Yanisa Del Toro, Dr. Joshua Lenchus, Dr. Jessica Figueroa,

Center for Research in Medical Education.

Dr. Stefanie Brown, Dr. Erin Marcus, Dr. Major Marco Ladino and Dr. Jessica Zuleta.

Above: All educational sites utilize the electronic medical records making patient care accessible and portable.

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High Impact Publications Endocrinology, Diabetes and Metabolism

Cardiovascular

Clinical Pharmacology

Hendel RC. The value and appropriateness of positron emission tomography: an evolving tale.J Nucl Cardiol. 2015;22:16-21.

Preston RA, Afshartous D, Rodco R, Alonso A, Garg D. Evidence for a Gastrointestinal-Renal Kaliuretic Signaling Axis in Humans. Kidney International; advance online publication 26 August 2015; doi:10.1038/ki.2015.243

Tanawuttiwat T, O’Neill BP, Cohen MG, Chinthakanan O, Heldman AW, Martinez CA, Alfonso CE, Mitrani RD, Macon CJ, Carrillo RG, Williams DB, O’Neill WW, Myerburg RJ: New-onset atrial fibrillation after aortic valve replacement: Comparison of transfemoral, transapical, transaortic and surgical approaches. J Am Coll Cardiol 2014; 63:1510-1519.

Ding W, Li J, Singh J, Alif R, Vazquez-Padron RI, Gomes SA, Hare JM, Shehadeh L (2015). miR-30e targets IGF2-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice. Cardiovasc Res. 2015 Apr 1;106(1):131-42. doi: 10.1093/cvr/ cvv030.

Badheka AO, Patel NJ, Singh V, Shah N, Chothani A, Mehta K, Deshmukh A, Ghatak A, Rathod A, Desai H, Savani GT, Grover P, Patel N, Arora S, Grines CL, Schreiber T, Makkar R, Rihal CS, Cohen MG, De Marchena E, O’Neill WW, Percutaneous Aortic Balloon Valvuloplasty in the US: A 13 years perspective. Am J Med 2014; 127: 744-753.

Badheka AO, Patel NJ, Grover P, Singh V, Patel N, Arora S, Chothani A, Mehta K, Deshmukh A, Savani GT, Patel A, Panaich SS, Shah N, Rathod A, Brown M, Mohamad T, Tamburrino FV, Kar S, Makkar R, O’Neill WW, De Marchena E, Schreiber T, Grines CL, Rihal CS, Cohen MG. Impact of annual operator and institutional volume on percutaneous coronary intervention outcomes: a 5-year United States experience (2005-2009). Circulation. 2014 Oct 14;130(16):1392-406.

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Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J. Reduction of proteinuria through podocyte alkalinization.

J Biol Chem 2014;289:17454-67.

Preston, RA, Afshartous D, Materson BJ, Alonso AB, Rodco R. Effects of Nebivolol versus Metoprolol on Sodium Sensitivity of Blood Pressure in Hispanic Postmenopausal Women with Hypertension. Hypertension 2014; 64:287-295.

Proschan MA, Ford CE, Graumlich JF, Cushman WC, Cutler, JA, Davis, BR, Pavlik V, Blumenthal SS, Franklin S, Alderman MH, Furberg CD, Castaldo RS, Dunn K, Preston, RA. How Much Effect of Different Antihypertensive Medications on Cardiovascular Outcomes is Attributable to Their Effects on Blood Pressure? Statistics in Medicine 2013;32:884-97.

Preston RA, Afshartous DA, Forte L, Rodco R, Alonso AB, Garg D, Raij L. Sodium challenge does not support an acute gastrointestinal-renal natriuretic signaling axis in humans. Kidney International 2012; 82:1313-1320.

Almaça J, Molina J, Arrojo e Drigo R, Abdulreda MH, Jeon WB, Berggren PO, Caicedo A, Nam HG (2014). Young capillary vessels rejuvenate aged pancreatic islets. Proc Natl Acad Sci USA, 111:17612-7.

Yu A, Snowhite I, Vendrame F, Rosenzwajg M, Klatzmann D, Pugliese A, Malek TR. Selective IL-2 Responsiveness of Regulatory T Cells Through Multiple Intrinsic Mechanisms Supports the Use of Low-Dose IL-2 Therapy in Type 1 Diabetes. Diabetes 2015 Jun;64(6):2172-83. doi: 10.2337/db14-1322.

Epub 2015 Jan 9.

Gastroenterology Damas OM, Deshpande AR, Avalos DJ, Abreu MT. Treating Inflammatory Bowel Disease in Pregnancy: The issues We Face Today. J Crohns Colitis. 2015 Jun 30.

Pii: jjv118. [Epub ahead of print] PMID: 26129693.

Lubarsky DA, Guercio JR, Hanna JW, Abreu MT, Ma Q, Uribe C, Birnbach DJ, Sinclair DR, Candiotti KA. The impact of anesthesia providers on major morbidity following screening colonoscopies. J Multidiscip Healthc. 2015 May 28; 8:255-70. doi: 10.2147/JMDH.S77408. eCollection 2015.

PMID: 26060404.

Yarur AJ, Kubiliun MJ, Czul F, Sussman DA, Quintero MA, Jain A, Drake KA, Hauenstein SI, Lockton S, Deshpande AR, Barkin JS, Singh S, Abreu MT. Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy. Clin Gastroenterol Hepatol. 2015 Jun;13(6):1118-1124. E3. doi: 10.1016/j. cgh.2014.12.026. Epub 2015 Jan 3. PMID: 25562796.

U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Yarur AJ, Jain A, Sussman DA, Barkin JS, Quintero MA, Princen F, Kirkland R, Deshpande AR, Singh S, Abreu MT. The association of tissue anti-TNF drug levels of serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study. Gut. 2015 Feb 10. pii: gutjnl-2014-308099. doi: 10.1136/ gutjnl-2014-308099. [Epub ahead of print].

PMID: 25670812.

General Internal Medicine Palacio AM1, Uribe C, Hazel-Fernandez L, Li H, Tamariz LJ, Garay SD, Carrasquillo O. Can phone-based motivational interviewing improve medication adherence to antiplatelet medications after a coronary stent among racial minorities? A randomized trial.

J Gen Intern Med. 2015 Apr;30(4):469-75.

Valencia WM, Florez H. Pharmacological treatment of diabetes in older people Diabetes Obes Metab. 2014 Dec;16(12):1192203. doi: 10.1111/dom.12362. Epub 2014 Sep 11. PMID:25073699.

Valencia WM, Stoutenberg M, Florez H. Weight loss and physical activity for disease prevention in obese older adults: an important role for lifestyle management.

Curr Diab Rep. 2014 Oct;14(10):539. doi: 10.1007/s11892-014-0539-4. Review. PMID: 25183491.

Giribaldi MG, Munoz A, Halvorsen K, Patel A, Rai P. MTH1 expression is required for effective transformation by oncogenic HRAS. Oncotarget is IF 6.6. pubmed/25893378.

Hematology-Oncology

Kenya S, Okoro I, Wallace K, Carrasquillo O, Prado G. Strategies to Improve HIV Testing in African Americans. J Assoc Nurses AIDS Care. 2015 Jul-Aug;26(4):357-67.

Mueller M, Purnell TS, Mensah GA, Cooper LA. Reducing racial and ethnic disparities in hypertension prevention and control: what will it take to translate research into practice and policy? Am J Hypertens. 2015 Jun;28(6):699-716.

Wilky BA, Kim C, McCarty G, Montgomery E, Kammers K, DeVine L, Cole RN, Raman V, Loeb DM. RNA Helicase DDX3: A novel therapeutic target in Ewing sarcoma. (In press, Oncogene).

Geriatrics and Palliative Medicine

Liu F, Cheng G, Hamard PJ, Greenblatt S, Wang L, Man N, Perna F, Xu H, Tadi M, Luciani L, Nimer SD. Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis. J Clin Invest.

2015 Aug 10. PMID: 26258414.

He M, Cortizas EM,Verdun RE, Severinson E.Cyclin-Dependent Kinases Regulate Ig Class Switching by Controlling Access of AID to the Switch Region.J Immunol194(9):4231-9, 2015.

Zhou W, Slingerland JM, Links between steroid receptor activation and proteolysis: potential relevance to therapy of hormone regulated cancers. Nature Reviews Cancer 2014; 14: 26-38.

Curtis KM, Aenlle KK, Frisch RN, Howard GA. TAp63y and ∆Np63ß promote osteoblastic differentiation of human mesenchymal stem cells: Regulation by vitamin D3 metabolites. PLoS One, 10:e0123642, 2015.

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Lu X, Sicard R, Jiang X, Stockus JN, McNamara G, Abdulreda M, Mov VT, Landgraf R, Lossos IS, HGAL localization to cell membrane regulates B-cell receptor signaling, Blood. 2015 Jan 22, 125(4): 649-57. PMID: 25381061.

Swords RT, Erba HP, DeAngelo DJ, Bixby DL, Altman JK, Maris M, Hua Z, Blakemore SJ, Faessel H, Sedarati F, Dezube BJ, Giles FJ, Medeiros BC, Pevonedistat (MLN4924), a First-in-Class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes: a phase 1 study, Br J Haematol, 2015 May, 169(4): 534-43.

Hepatology Bhamidimarri KR, Frank C, Adam P, Levy C, Maria H, Jeffers L, David R, Schiff E, O’Brien C, Martin P. Safety, efficacy and tolerability of half-dose sofosbuvir plus simeprevir in treatment of Hepatitis C in patients with end stage renal disease. J Hepatol. 2015 Jun 18. pii: S0168-8278(15)003943. doi: 10.1016/j.jhep.2015.06.004. PMID: 26095179.

Grigorian AY, Mardini HE, Corpechot C, Poupon R, Levy C. Fenofibrate is effective adjunctive therapy in the treatment of primary biliary cirrhosis: A meta-analysis. Clin Res Hepatol Gastroenterol. 2015 Jun;39(3):296306. doi:10.1016/j.clinre.2015.02.011. Epub 2015 Apr 14. J Gastrointest Cancer. 2015 May 20. [Epub ahead of print] Gutierrez JA, Carrion AF, Avalos D, O’Brien C, Martin P, Bhamidimarri KR, Peyton A. Sofosbuvir and simeprevir for treatment of hepatitis C virus infection in liver transplant recipients. Liver Transpl. 2015 Jun;21(6):823-30. doi: 10.1002/lt.24126.

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High Impact Publications Hospital Medicine Cohn, S: Updated guidelines on cardiovascular evaluations before noncardiac surgery: a view from the trenches Cleveland Clin. J. Volume 81. Pages 742-751. 15 Dec. 2014.

Cohn, S, Mushtaq, M: Perioperative betablockers in noncardiac surgery: the evidence continues to evolve” Cleveland Clin. J. Volume 81. Pages 501-512. 1 Aug. 2014.

Infectious Diseases Stapleton AE, Cox ME, DiNello RK, Geisberg M, Abbott A, Roberts P, Hooton TM. Performance of a New Rapid Immunoassay Test Kit for Point-of-Care Diagnosis of Significant Bacteriuria. J Clin Microbiol. 2015 Jun 10. pii: JCM.00353-15. [Epub ahead of print] PubMed PMID: 26063858.

George VK, Pallikkuth S, Parmigiani A, Alcaide M, Fischl M, Arheart KL, Pahwa S. HIV infection Worsens Age-Associated Defects in Antibody Responses to Influenza Vaccine. J Infect Dis. 2015 Jun 15;211(12):1959-68. doi:10.1093/infdis/ jiu840. Epub 2015 Jan 2. PubMed PMID: 25556252.

Nephrology and Hypertension Fornoni A, Merscher S, Kopp JB. Lipid biology of the podocyte: new perspectives offer new opportunities. Nature Review Nephrology, 10:379-88, 2014.

Duque JC, Martinez L, Mesa A, Wei Y, Tabbara M, Salman LH, Vazquez-Padron RI. CD4+ lymphocytes improve venous blood flow in experimental arteriovenous fistulae.

Surgery. 158:529-36, 2015.

Sun HY, Alexander BD, Huprikar S, Forrest GN, Bruno D, Lyon GM, Wray D, Johnson LB, Sifri CD, Razonable RR, Morris MI, Stoser V, Wagener MM, Singh N. Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression. Clin Infect Dis. 2015 Jan 1;60(1):36-44. doi: 10.1093/cid/ ciu711. Epub 2014 Sep 9. PubMed PMID: 25210020.

Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, HilfikerKleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med. 21:601-9, 2015.

Rothenberger MK, Keele BF, Wietgrefe SW, Fletcher CV, Beilman GJ, Chipman JG, Khoruts A, Estes JD, Anderson J, Callisto SP, Schmidt TE, Thorkelson A, Reilly C, Perkey K, Reimann TG, Utay NS, Nganou Makamdop K, Stevenson M, Douek DC, Haase AT, Schacker TW. Large number of rebounding/ founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1126-34. doi: 10.1073/pnas.1414926112. Epub 2015 Feb 23. PubMed PMID: 25713386; PubMed Central PMCID: PMC4364237.

Munoz Mendoza J, Arramreddy R, Schiller B. Dialysate Sodium: Choosing the Optimal Hemodialysis Bath.Am J Kidney Dis. 2015 May 15. pii: S0272-6386(15)00630-7. doi: 10.1053/j.ajkd.2015.03.034. [Epub ahead of print]

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Gaynor JJ, Ciancio G, Guerra G, Sageshima J, Hanson L, Roth D, Goldstein MJ, Chen L, Kupin W, Mattiazzi A, Tueros L, Flores S, Barba LJ, Lopez A, Rivas J, Ruiz P, Vianna R, Burke GW 3rd. Single-centre study of 628 adult, primary kidney transplant recipients showing no unfavourable effect of new-onset diabetes after transplant. Diabetologia.

58:334-45, 2015.

Pulmonary, Allergy, Critical Care and Sleep medicine Quittner A., O’Donnell A., Salathe M.A., Lewis S., McKevitt M., Li X., Montgomery A.B., O’Riordan T., Barker A. Quality of Life Questionnaire-Bronchiectasis: Final Psychometric Analyses and Determination of Minimal Important Difference Scores.

Thorax 2015; 70: 12-20.

Geraghty P, Eden E, Pillai M, Campos M, McElvaney NG, Foronjy RF. ∂-1 Antitrypsin Activates Protein Phosphatase 2A (PP2A) to Counter Lung Inflammatory Responses. Am J Respir Crit Care Med. 2014 90(11):122942.

Glassberg MK, Choi R, Manzoli V, Shahzeidi S, Rauschkolb P, Voswinckel R, Aliniazee M, Xia X, Elliot SJ. Endocrinology. 2014 Feb; 155(2):441-8. doi: 10.1210/en.2013-1345.

Epub 2013 Nov 25.

Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JHM, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, Groen HJM, Postma DS, Wanner A, Rouhani FN, Brantly ML, Powell R, Smith BM, Rabinowitz D, Raffel LJ, Hinckley Stukovsky KD, Crapo JD, Beaty TH, Hokanson JE, Silverman EK, Dupuis J, O’Connor GT, Boezen HM, Rich SS, Barr RG. Genome- wide study of percent emphysema on CT in the general population: The MESA Lung/ SHARe Study. Am J Respir Crit Care Med 2014; 189:408-418

U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Peyrani P, Wiemken TL, Kelley R, Zervos MJ, Kett DH, File Jr. TM, Stein GE, Ford KD, Scerpella EG, Welch V, Ramirez JA and the IMPACT-HAP Study Group. Higher Clinical Success in Patients with Ventilator-Associated Pneumonia due to Methicillin-Resistant Staphylococcus aureus Treated with Linezolid Compared with Vancomycin: Results from the IMPACT-HAP Study. Crit Care. 2014: 10;18:R118. (doi:10.1186/cc13914).

Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JHM, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, Groen HJM, Postma DS, Wanner A, Rouhani FN, Brantly ML, Powell R, Smith BM, Rabinowitz D, Raffel LJ, Hinckley Stukovsky KD, Crapo JD, Beaty TH, Hokanson JE, Silverman EK, Dupuis J, O’Connor GT, Boezen HM, Rich SS, Barr RG. Genomewide study of percent emphysema on CT in the general population: The MESA Lung/ SHARe Study. Am J Respir Crit Care Med 2014; 189:408-418 Rheumatology and Immunology Carpintero MF, Martinez L, Fernandez I, Romero AC, Mejia C, Zang YJ, Hoffman RW, Greidinger EL. Diagnosis and risk stratification in patients with anti-RNP autoimmunity. Lupus. 2015 Mar 2. pii: 0961203315575586. [Epub ahead of print] Chen J, Doyle TJ, Liu Y, Aggarwal R, Wang X, Shi Y, Ge S-X, Huang H, Lin Q, Liu W, Cai Y, Koontz D, Fuhrman C, Golzarri MF, Liu Y, Hatabu H, Nishino M, Araki T, Dellarippa PF, Oddis CV, Rosas IO, and Ascherman DP. Biomarkers of Rheumatoid Arthritis-associated Interstitial Lung Disease, Arthritis and Rheum. 67: 28-38, 2015.

Zang Y, Martinez L, Fernandez I, PignacKobinger J, Greidinger EL. Conservation of Pathogenic TCR Homology across Class II Restrictions in Anti-Ribonucleoprotein Autoimmunity: Extended Efficacy of T Cell Vaccine Therapy. J Immunol. 192(9):4093102, 2014.

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Harlow L, Gochuico B, Rosas IO, Doyle TJ, Osorio JC, Travers TS, Camacho CC, and Ascherman DP. Anti-Citrullinated Heat Shock Protein 90 Antibodies Isolated from Bronchoalveolar Lavage Fluid are a Marker of Lung-Specific Immune Responses, Clin Immunol. 155: 60-70, 2014.

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Diversity Diversity Committee The Diversity Committee in the Department of Medicine was established by Roy Weiss, MD, PhD in 2014 to develop a more comprehensive workforce representative of the academic and patient community. The committee members include Marilyn Glassberg, MD, Stephen Symes, MD, and Stefanie Brown, MD. Initial review of the Department focused on understanding the gender, race and ethnic aspects of the area. Although there was significant diversity, there was a need for improvement in hiring and promotion activities specifically for women and under-represented minorities— including African-Americans.

The focus for the upcoming academic year will be to review data for individual divisions with division chiefs and faculty, forecast attention on the hiring of women and minority faculty with each new recruitment,

include manager performance in diversity issues as a core competency measure, and promote unconscious bias training for faculty search committees, resident and fellowship admissions committees, and administrative staff.

The Diversity Committee will work closely with Erin Kobetz, MD, Senior Associate Dean for Health Disparity, to pilot these initiatives across the medical campus and establish a core Grand Round lecture series emphasizing Health Disparities.

Women’s Committee Women In Academic Medicine (WIAM) seeks to cultivate a larger leadership base for Miller School women faculty and works to ensure that the School promotes an environment that values every member of the University community, while providing the resources necessary to fulfill a commitment to women faculty. This dynamic group is under the leadership of Lilian Abbo, MD (President) and Ivette Motola, MD (Vice President).

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U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Philanthropy Thanks to recent breakthroughs, the Miller School of Medicine is on the cusp of landmark developments in medicine that have the potential to create major advances in the treatment of many life-threatening conditions.

Outstanding academic healthcare institutions like the University of Miami depend on the continued charitable contributions of generous donors who invest in the education of physicians and the discoveries yet to be made.

The backbone of the medical school, the Department of Medicine, represents over 341 physicians, with appointments in its 14 Divisions. Gifts in support of the Department help advance medical science, develop new treatments and cures, train new generations of physician scientists, and improve the health of those in Miami, South Florida and beyond. The Department of Medicine wishes to extend its deepest thanks to the many loyal donors for their profound and continued generosity.

DR. BAHARAK MOSHIREE HONORED WITH THE CHESTER CASSEL ENDOWED CHAIR IN GASTROENTEROLOGY At a ceremony before friends, colleagues, and Miller School of Medicine leadership, Baharak Moshiree, MD, MS, Director of Motility in the Division of Gastroenterology, was presented with the Chester Cassel Endowed Chair in Gastroenterology.

The ceremony, which took place June 9, 2015 at the Lois Pope LIFE Center, added its newest member to an already impressive roster of 13 endowed chairs at the Department of Medicine. Pascal J. Goldschmidt, MD, Senior Vice President for Medical Affairs and Dean of the Miller School of Medicine, stated that an endowed chair is one of the highest honors bestowed at leading universities.

“An endowed chair is provided to world-class scholars to support their research and education programs in perpetuity,” said Dr. Goldschmidt, who is also CEO of UHealth, the University of Miami Health System.

“Brilliant physician researchers such as Dr. Moshiree receive well-deserved recognition for outstanding achievements in their field. Institutions realize the benefits and prestige of recruiting the best and brightest faculty, and generations of students will have the opportunity to learn from world-class professors.”

The endowed chair was established in honor of its namesake, Chester Cassel, MD, who was one of the first fully qualified gastroenterologists in Florida. His career, which paralleled the growth of the medical school, had a tremendous impact on the development of the Department of Medicine, and most especially its Division of Gastroenterology.

D epar t men t o f Medi c in e C h air man ’s R e po r t 2015

Department of Medicine Endowed Chairs and Professorships Kathleen and Stanley Glaser Distinguished Chair Roy E. Weiss, MD, PhD American Heart Association Chair in Cardiovascular Research Robert J. Myerburg, MD Louis Lemberg, MD Chair in Cardiology Joshua M. Hare, MD Martin H. Kalser, MD Chair in Gastroenterology Maria T. Abreu, MD Sol Cye Mandel Chair in Gastroenterology Jeffrey B. Raskin, MD Chester Cassel Chair in Gastroenterology Baharak Moshiree, MD William J. Harrington, MD Chair in Hematology-Oncology Joseph D. Rosenblatt, MD William Way Anderson, MD Chair in Nephrology David Roth, MD Joseph Weintraub Family Foundation Chair in Pulmonary Diseases Adam Wanner, MD Mary Jane Sertel Professorship in Pulmonary Diseases Matthias Salathe, MD Courtelis Distinguished Chair in Medical Oncology Pasquale W. Benedetto, MD Walter G. Ross Chair in Vascular Biology Keith Webster, PhD Peggy and Harold Katz Family Chair for Kidney and Vascular Disease Research Alessia Fornoni, MD, PhD

From left to right: Dr. Pascal J. Goldschmidt, Dr. James E. McGuigan, Chester Cassel’s daughters, Laurie Cassel Libros and Karen Carter, Dr. Maria T. Abreu, Dr. Roy E. Weiss. Seated: Dr. Baharak Moshiree

“Gastroenterology is a world-class division whose mission is not only to provide the most excellent clinical care for its patients, but to discover new treatments and educate the next generation of leaders,” said Roy E. Weiss, MD, PhD, the Kathleen and Stanley Glaser Distinguished Chair in Medicine, and Chair of the Department of Medicine.

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Residents and Fellows Name Medical School

General Internal Medicine PGY-1 - Categorical Algaze, Sandra Bromante, Stephanie Brown, Kevin Byrnes, Diana Castellanos, Raul Catoe, Heath Dabas, Nitika Dauer, Ryan Dillon, David Fernandes, Marcelo Garner, Salih Gosine, Adhiraj Johnson, Shawntira Keihanian, Tara Kennedy, Rachel Lowery, Megan Parmar, Rajiv Pereira, Reginald Pontee, Nicole Rivner, Harold Rodriguez, Gracielena Schmidtman, Jenna Smith, Lauren Taldone, Sabrina

Universidad Central del Caribe School of Medicine Nova Southeastern University College of Osteopathic Medicine Chicago Medical School at Rosalind Franklin University of Medicine and Sciences University of Miami Leonard M. Miller School of Medicine Florida State University College of Medicine University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Charles E. Schmidt College of Medicine at Florida Atlantic University Duke University School of Medicine Howard University College of Medicine University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Tehran University of Medical Sciences University of Miami Leonard M. Miller School of Medicine Temple University School of Medicine University of Texas Southwestern Medical Center University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Medical College of Georgia University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Howard University College of Medicine University of Miami Leonard M. Miller School of Medicine

PGY-1 William J. Harrington Latin American Training Program Blumer, Vanessa Universidad Central de Venezuela Escuela de Medicina Luis Razetti Bravo, Gabriela Universidad San Francisco de Quito Colegio de Ciencias de la Salud, Ecuador Cortesi, Camilo Universidad del Desarrollo Facultad de Medicina, Sede Santiago, Chile Costa Fernandes Filho, Gilson Universidade Federal da Paraiba (UFPB) Centro de Ciencias Medicas, Brazil De La Cruz, Indhira Instituto Technologico de Santo Domingo (INTEC) Facultad de Salud Ibrahim, Michel Universidad Iberoamericana (UNIBE) School of Medicine,

Santo Domingo, Dominican Republic Morillas Rodriguez, Jose Universidad Nacional de Trujillo Facultad de Medicina, Peru Pacheco Cano, Carlos Universidad del Mayab Escuela de Medicina, Mexico Rivera Maza, Manuel Universidad Dr. Jose Matias Delgado Escuela de Medicina, El Salvador Sinanan, Rajiv University of the West Indies Faculty of Medicine St. Augustine, Trinidad Suarez, Jose Universidad de la Sabana Facultad de Medicina, Colombia Zavala, Bruno Universidad Catolica Nuestra Senora de la Asuncion Facultad de Ciencias

de la Salud, Asuncion, Paraguay

40

PGY-1 Preliminary Year Ashkenazy, Noy Cogorno, Mariela Cox, Audrey Duerr, Eric Falto-Aizpurua, Leyre Karantalis, Vasileios Kelsey, Andrew Nguyen, Linda Ott, Cody Paul, Suchismita Restrepo Cardenas, Juan Varghese, Mathew

University of Miami Leonard M. Miller School of Medicine Universidad Central de Venezuela Escuela de Medicina Luis Razetti University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Ponce School of Medicine and Health Sciences University of Patras School of Health Sciences University of Connecticut School of Medicine University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Harvard Medical School Universidad del Valle Escuela de Medicina, Cali, Colombia University of Miami Leonard M. Miller School of Medicine

PGY2 Al Sharhan, Loulwa Ashukem, Moses Badlani, Jayshiv Brice, Aaron Chapman, Ryan Diaz, Carlos Henderson, Armen Kirolos, Irene Laderian, Bahar Mason, Ajani Morel, Charlotte Mosetti, Maria Antonietta Muenyi, Valery

Kuwait University Virginia Commonwealth University School of Medicine University of Pittsburgh School of Medicine University of Virginia School of Medicine Nova Southeastern University College of Osteopathic Medicine Rush Medical College of Rush University School of Medicine Meharry Medical College Misr University for Science and Technology University of Pittsburg School of Medicine Howard University College of Medicine New York Medical College Universita degli Studi di Roma’La Sapienza’ Facolta di Medicina e Psicologia Meharry Medical College U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Name Medical School

Nguyen, Nhi Puig, Enrique Quiles Lapuerta, Francisco Saravia, Diana Scherfenberg, Naomi Schwartz, Marc Thekkumkattil, Anu Tookes, Hansel Vitolo, Melissa Watford, Daniel Wu, Grace

Washington University in St. Louis School of Medicine Ponce School of Medicine Universidad de Granada University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine The School of Medicine at Stony Brook University Medical Center University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Jefferson Medical College of Thomas Jefferson University University of North Carolina at Chapel Hill School of Medicine University of Illinois at Chicago College of Medicine

PGY-2 William J. Harrington Latin American Training Program Chavez Morales, Efren Alejandro Universidad Autonoma de Chihuahua, Mexico de la Cruz Luque, Celso Fernando Universidad Peruana Cayetano Heredia, Peru Duque Ballesteros, Juan Camilo Universidad de la Sabana, Colombia Dvorquez, Denise Universidad Catolica de Santiago de Guayaquil, Ecuador Kimble, Erik Lesley Universidad de Guadalajara, Mexico Lorio, Marco Universidad Nacional Autonoma de Nicaragua, Managua Malpica Castillo, Luis Enrique Universidad Peruana Cayetano Heredia, Peru Mendirichaga, Rodrigo Universidad de Moterrey, Mexico Monge Urrea, Jorge Universidad Anahuac, Mexico Nunez Breton, Jonatan David Pontificia Universidad Catolica Madre y Maestra (PUCMM),DR Pardinas Gutierrez, Miguel Agustin Westhill Institute, Mexico Pena Polanco, Nathalie Aurora Pontificia Universidad Catolica Madre y Maestra (PUCMM),DR PGY-3 Alansari, Yahya Armstrong, Antonio Augustin, Dimitri Bahadu, Shaka Berbel Caban, Ana Calzadilla, Andrew DeMaria, Peter Elden, Andrew Fernandez, Rafle Fernandez de la Vara, Aymara Garcia, Alexander Gilinsky, Dani Joshi, Shivam Justmann, Courtney Karsner, Ryan Kataria, Rahul Khalid, Laiqua Ramdial, Jeremy Sparrow, Quinton Vilches, Elizabeth Vu, Ann Ying, David

Arabian Gulf University Ponce School of Medicine University of Miami Leonard M. Miller School of Medicine Weill Cornell Medical College Ponce School of Medicine Florida State University College of Medicine University of Miami Leonard M. Miller School of Medicine UMDNJ-New Jersey Medical School University of Miami Leonard M. Miller School of Medicine Temple University School of Medicine Nova Southeastern University College of Osteopathic Medicine University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine George Washington University School of Medicine and Health Sciences Temple University School of Medicine Aga Khan Medical College University of Miami Leonard M. Miller School of Medicine University of Miami Leonard M. Miller School of Medicine Universidad Central del Caribe School of Medicine University of Miami Leonard M. Miller School of Medicine Washington University of St. Louis School of Medicine

PGY-3 William J. Harrington Latin American Training Program Arciniegas, Rafael Universidad Central de Venezuela – Jose Maria Vargas, Venezuela Bueno Rios, Maria X. Universidad San Martin de Porres, Peru Corral, Juan E. Universidad Francisco Marroquin, Guatemala Diaz, Liege I. Universidad de Panama, Panama Dookhan, Christina M. University of the West Indies, Trinidad Gallastegui Crestani, Nicolas Universidad San Martin de Porres, Peru Gomez Arteaga, Alexandra Universidad de los Andes, Santa Fe de Bogota, Colombia Hernandez, Rafael E. Universidad Iberoamericana, Santo Domingo, Dominican Republic Nascimento Cardoso, Rhanderson M. Faculdade de Medicina da Universidade Federal de Goias, Brazil Novoa, Italo C. Universidad Peruana Cayetano Heredia, Peru Perez, Sergio A. Universidad del Valle, Cali, Colombia Torres, Alfredo E. Universidad de Carabobo, Valencia, Venezuela

Cardiovascular

Current Position Location of Residency

Alsulaimi, Ali Agarwal, Zubin Chongthmmakun, Vasukatakarn Emaminia, Abbas Gomez, Camilo Lucero, Thomas

PGY4 PGY4 PGY4 PGY4 PGY4 PGY4

Jackson Memorial Hospital-Univ. of Miami University of Vermont Cleveland Clinic Foundation New York Medical College Valhalla Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami

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Residents and Fellows Name

Current Position Location of Residency

Patel, Nileshkumar Rodriguez, Alexis Braghiroli, Joao Elias, Elliott Hawk, Christopher Hernandez, Gabriel Mushtaq, Muzammil Patel, Nish Smairat, Ramez Fox, Arieh Goyal, Vishal Karnabi, Eddy Khazai, Bahram Macatangay, Constancia Singh, Vikas

PGY4 PGY4 PGY5 PGY5 PGY5 PGY5 PGY5 PGY5 PGY5 PGY6 PGY6 PGY6 PGY 6 PGY 6 PGY 6

Staten Island University Hospital Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Icahn School of Medicine at Mount Sinai, New York Columbia University Medical Center- New York Jackson Memorial Hospital-Univ. of Miami Mount Sinai School of Medicine, New York University of Oklahoma Health Sciences Center Jackson Memorial Hospital-Univ. of Miami Columbia University Medical Center- New York Allegheny General Hospital-Western Pennsylvania Hospital, Pittsburgh Yale New Haven Hospital, New Haven Loma Linda University, Loma Linda University of Connecticut Health Center-Hartford Jackson Memorial Hospital-Univ. of Miami

PGY7 PGY7 PGY7

Orlando Health Penn State College of Medicine Jackson Memorial Hospital-Univ. of Miami

PGY7

University of Illinois

PGY4 PGY4 PGY4 PGY4 PGY4 PGY5 PGY5 PGY5 PGY5 PGY5 PGY5

University of Pittsburg Medical Center Broward Health Jackson Memorial Hospital-Univ. of Miami Jersey City Medical Center University of Florida – Jacksonville Internal Medicine, Maimonides Medical Center Morristown Medical Center Cleveland Clinic Florida Jackson Memorial Hospital-Univ. of Miami Lahey Hospital and Medical Center Jackson Memorial Hospital-Univ. of Miami

PGY4 PGY4 PGY5 PGY5

Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Mount Sinai Medical Center, Miami, FL Cooper Med. Sch. Rowan Univ. Hosp., Camden, NJ

PGY7

Jackson Memorial Hospital-Univ. of Miami

PGY5 PGY4 PGY5 PGY4 PGY6 PGY4 PGY4 PGY5 PGY5 PGY6 PGY4 PGY5 PGY6 PGY6

Jackson Memorial Hospital-Univ. of Miami, FL Jackson Memorial Hospital-Univ. of Miami, FL Jackson Memorial Hospital-Univ. of Miami, FL Icahm School of Medicine Mt. Sinai, New York, NY Jackson Memorial Hospital-Univ. of Miami, FL Jackson Memorial Hospital-Univ. of Miami, FL Columbia University, New York, NY Browne University, Rhode Island, RI Washington University, St. Louis, MO Jackson Memorial Hospital-Univ. of Miami, FL Albert Einstein College of Medicine, New York, NY Jackson Memorial Hospital-Univ. of Miami, FL Johns Hopkins Bayview Med. Center, Baltimore, MD University of Maryland Med. Center. Baltimore, MD

Interventional Badiye, Amit Damluji, Abdulla Dyal, Michael

Electrophysiology Healy, Chris

Infectious Diseases Anjan, Shweta Hall, Toni Goldenberg, Vanessa Rodriguez, Anamaria Sternberg, Candice Groner, Mordechai Hurtado Gomez, Gabriel Lakshmi, Seetha Rosa, Rossana Shaikhomer, Mohammed Shimose, Luis

Rheumatology Fernandez, Karen LaConti, Joseph Singh, Shelley Zanotti, Magali

Hepatology Sclair, Seth

Gastroenterology Barkin, Jodie Berera, Shivali Calmet, Fernando Croteau, Ryan Czul, Frank Donet, Jean Goel, Akash Gosalia, Ashil Kalra, Gorav Kingsley, Michael Kim, Su Bin Perlini, Erin Rabiee, Atoosa Szeto, Winnie

Nephrology and Hypertension Garcia, Desiree Dejman, Adriana Pagan, Javier Kusnir, Juan Abu Grara, Hazem 42

PGY4 PGY4 PGY4 PGY4 PGY5

Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami IM Texas Tech University U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Name

Current Position Location of Residency

Sabucedo, Alberto Cardona-Guzman, Jose Miguel Valdes, Alejandro Garcia, Rene A.

PGY5 PGY5 PGY5 PGY5

University of South Florida- USF Health IM Orlando Regional Medical Center Jewish Hospital of Cincinnati Jewish Hospital of Cincinnati

Endocrinology, Diabetes and Metabolism Hannoush, Zeina Palacios Merchan, Juan Banga, Pritisheel Gra Menendez, Silvia Mohseni, Mahshid Perez Bustamante, Marcela Rosen Berger, Hara

PGY4 PGY4 PGY4 PGY5 PGY5 PGY5 PGY5

Jackson Memorial Hospital-Univ. of Miami University of Miami-Regional Campus UCSF Fresno, CA Cleveland Clinic-Weston Florida Internal Medicine, Huntington, WV University of Miami-Regional Campus Mount Sinai Medical Center-Miami Beach

PGY4 PGY4 PGY4 PGY4 PGY4 PGY4 PGY5 PGY5 PGY5 PGY5 PGY6 PGY6 PGY6 PGY6 PGY6 PGY6

NSLIJHS/Hofstra North Shore – LIJ School of Med. Weiss Memorial Hospital, Chicago, IL Rutgers University-New Jersey Medical School Mount Sinai St. Luke’s Roosevelt Hospitals Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Metropolitan Hospital Center, NY Medical College Memorial Hospital of Rhode Island Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Staten Island University Hospital Program University of Buffalo School of Medicine Nassau University Medical Center Chicago Medical School/Rosalind Franklin Univ. of Med. and Sci. Harbor Hospital Center Jackson Memorial Hospital-Univ. of Miami

PGY4 PGY4 PGY4 PGY4 PGY4 PGY5 PGY5 PGY5 PGY5 PGY5 PGY5 PGY6 PGY6 PGY6

Jackson Memorial Hospital-Univ. of Miami Yale/Griffin Hospital New Haven University of Miami-Regional Campus Jackson Memorial Hospital-Univ. of Miami Southern Illinois University School of Medicine Jackson Memorial Hospital-Univ. of Miami Jackson Memorial Hospital-Univ. of Miami Virginia Commonwealth University Health System Jackson Memorial Hospital-Univ. of Miami University of Miami Miller School/Palm Beach Cleveland Clinic (Florida) Program University of South Florida Jamaica Hospital Medical Center Program Jackson Memorial Hospital-Univ. of Miami

PGY4 PGY4 PGY5 PGY5

Beth Israel, NYC Jackson Memorial Hospital-Univ. of Miami SUNY Health Science Center St. Luke’s Roosevelt Hospital Center

PGY4 PGY4 PGY4 PGY4 PGY1 PGY6 PGY4 PGY4 PGY4

Texas Tech., Amarillo, Texas Metropolitan Hospital, New York, NY Instituto Salvadoreno del Seguro Social, El Salvador University of Connecticut, CT Sri Zenkateswara Medical College, India Sinai Hospital of Baltimore, Baltimore, MD Texas Tech., Amarillo, Texas Jackson Memorial Hospital-Univ. of Miami Lutheran Medical Center, NY

PGY5 PGY5 PGY5

Ochsner Medical Center, New Orleans, LA Bella Vista Hospital, Mayaguez, PR Lutheran Medical Center, Brooklyn, NY

Hematology-Oncology Bradley, Terrence El Dinali, Mohamed Nahas, George Park, Wungki Rubin, Stacy Salzberg, Matthew Alderuccio, Juan Desai, Amrita Sandoval, Ana Vargas, Fernando Azzi, George Dawar, Richa Hurtado-Cordovi, Jorge Parajuli, Ritesh Tinoco, Gabriel Warsch, Sean

Pulmonary-Critical Care Buryk, Yaroslav Choudhry, Bassam El Khatib, Ahmad Latibeaudiere, Rachel Wynn, Nikki Brito, Yoel Farquharson, Lesley Kwasnik, Aleksandra Miller, Shelly Sarmento, Bianca Schwartz, Randall Dickens, Sonja Paredes Aller, Sheyla Sneij, Waleed

Critical Care Askari, Kyan Rico, Rene Medford, Marlon Rosario Luis Roberto

Geriatrics Alshanberi, Asim Muhammed Bueno, Yolin A. Castellanos Gonzalez, Raquel Cruz, Lorinda Karanam, Chandana Kaur, Arshpreet Khojah, Yazeed A Lisigurski Teitelman, Miriam Macias-Madaula, Junior

Palliative Medicine Walwyn, Emron McMullen, Beatriz Medina, Suleyki

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Residents and Fellows Name

Current Position Medical School

John F Kennedy Hospital in West Palm Beach Residents Preliminary Callahan, Morgan Daubert, Jacquelyn Harvey, Marie Joshi, Nirav Karli, Sapir Sienkiewicz, Adam Syed, Sarah

PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1

University of Miami Miller School of Medicine, Miami, FL University of Miami Miller School of Medicine, Miami, FL University of Miami Miller School of Medicine, Miami, FL University of Miami Miller School of Medicine, Miami, FL University of Miami Miller School of Medicine, Miami, FL University of Miami Miller School of Medicine, Miami, FL University of Miami Miller School of Medicine, Miami, FL

Categorical Abdelmalak, Farid Aliyeva, Tatyana Bhuiyan, Mohammed Bitincka, Gent Camacho, Juan Chishti, Imran Choi, Jaehyoung da Silva, Alexis Desai, Trishla Dionne, Benjamin Dold, Jessika Elballat, Elsayed Fu, Kevin Hakimian, Stephanie Kapila, Kunal Mayes-Romero, Mario Morales, Ximena Roman, Diana Sehatbakhsh, Seminah Shah, Atif Tharpe, Rashida Witteman, Michael Bethel-Ellison, Samantha Embry, Faneece Furlan, Stefanie Garnet, Brian George, Griffen Giscombe, Lisa-Gaye Haque, Nyrene Khalil, Maya Koka, Sagarika Kreidieh, Omar Kushnir, Alexander Lee Ching, Cathy Mercado, Julio Mulee, Jacqueline Pazin, Benjamin Pino Moreno, Jesus Sarkis, Fayez Sautter, Robert Shah, Varun Valle Goffin, Janeiro Vega Blanco, Roger Wang, Danlu Al Yaseen, Saif Aldana Campos, Martin Alrifai, Abdulah Aubel, Troy Avalos, Danny Bunton, Cristina Dassouki, Saleh Gleitmann, Lisa Hayes, Edwin Kabach, Mohamad Kostioukhina, Ekaterina Marian, Diana Morales, Fabio Negron, Rebecca Pathak, Vishesh Porter, Jessica Rives-Sanchez, Marisela Solanki, Ekta Tambini, Pamela Torres, Yolaine Valluri,Sri Kartik Vijayvargiya, Prakhar

PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY1 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY2 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3 PGY3

George Washington University, Washington, DC George Washington University, Washington, DC University of Miami Miller School of Medicine, Miami, FL University of South Florida College of Medicine, Tampa, FL San Juan Bautista Escuela De Mediciina, Caguas, PR University of Illinois College of Medicine, Chicago, IL Korea University College of Medicine, Seoul, S. Korea Morehouse School of Medicine, Atlanta, GA Rajarshi Chhatrapati Shahu Maharaj Government Medical College Kolhapur, Kolhapur, India Wayne State University School of Medicine, Detroit, MI Charles E. Schmidt College of Medicine at Florida Atlantic University, Boca Raton, FL Tanta University Faculty of Medicine, Tanta, Egypt University of Miami Miller School of Medicine, Miami, FL American University of Beirut Faculty of Medicine, Beirut, Lebanon Government Medical College Patiala, Patiala ,Punijab, India FIU Herbert Wertheim College of Medicine, Miami, FL Fundacion Universitaria Juan N. Corpas, Colombia University of Miami Miller School of Medicine, Miami, FL Birjand University of Medical Sciences and Health Services, Birjand, Iran University of Miami Miller School of Medicine, Miami, FL University of South Florida College of Medicine, Tampa, FL FIU Herbert Wertheim College of Medicine, Miami, FL Howard University College of Medicine, Washington, DC Medical College of Georgia, Augusta, GA Nova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL University of Miami Miller School of Medicine, Miami, FL University of Queensland School of Medicine, Herston, Australia Ross University School of Medicine, Roseau, Dominica University of Kentucky College of Medicine, Lexington, KY American University of Beirut Faculty of Medicine, Beirut, Lebanon Royal College of Surgeons in Ireland School of Medicine, Dublin, Ireland American University of Beirut Faculty of Medicine, Beirut Lebanon Florida State University College of Medicine, Tallahassee, FL Universidad Catolica de Santiago de Guayaquil Facultad de Ciencias, Guayaquil, Ecuador Ross University School of Medicine, Roseau, Dominica American University of the Caribbean School of Medicine, Cupecoy, Saint Maarten Ross University School of Medicine, Roseau, Dominica Fundacian Universitaria San Martan Facultad de Medicina, Bogota, Colombia American University of Beirut Faculty of Medicine, Beirut, Lebanon Ross University School of Medicine, Roseau, Dominica Rajarshi Chhatrapati Shahu Maharaj Government Medical College Kolhapur, Kolhapur, India Universidad Americana (UAM) Facultad de Medicina, Managua, Nicaragua Universidad Nacional Auanoma de Nicaragua Facultad de Ciencias, Managua, Nicaragua Nova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL Al-Kindi college of Medicine, University of Bahhdad, Iraq Universidad Industrial de Santander, Colombia University of Damascus, Syria University of Miami Miller School of Medicine, Miami, FL Ross University School, Roseau, Dominica Howard University College of Medicine, Washington, DC Kauno Medicinos Universitetas, Kaunos, Lithuania American University of the Caribbean,Cupecoy, Saint Maarten University of Miami Miller School of Medicine, Miami, FL University of Damascus, Damascus, Syria University of Miami Miller School of Medicine, Miami, FL Fundacion Universitaria San Martin, Bogota, Colombia Ross University School, Roseau, Dominica Ross University School, Roseau, Dominica Nova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL Ross University School, Roseau, Dominica San Juan Bautista Escuela de Medicina, Caguas, PR Nova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL Ross University School, Roseau, Dominica Universidad Iberoamericana, Santo Domingo, Dominican Republic Bhaskar Medical College, Yenkapally, India Grant Medical College, Mumbai, India

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U H ea l t h | U n i v er s i t y o f M i a m i M i l l er Sch o o l of Med i c i ne

Resident Name Medical School

Medicine-Pediatrics PGY-1 Botros, Diana

Brandon, Theodora Jimenez-Bacardi, Adria Khidir, Hana

Lott, Margaret

University of Miami Leonard M. Miller School of Medicine Medical College of Georgia Regents University University of Pittsburg School of Medicine University of Iowa Roy J. Lucille A. Carver College of Medicine University of Pittsburg School of Medicine

PGY-2 Flowers, Chad Petrauskis, Christian Saxena, Anjali

Schneider, Jessica Thorngren, Daniel

Indiana University School of Medicine Georgetown University School of Medicine University of Arkansas for Medical Sciences College of Medicine University of Colorado School of Medicine University of Chicago Pritzker School of Medicine

PGY-3 Gonzalez, Samantha Meza, Benjamin Park, Jane Parris, Brent Van Kirk, Kendra

Ponce School of Medicine and Health Sciences University of Pittsburgh School of Medicine University of Colorado Denver School of Medicine Stony Brook University School of Medicine Howard University College of Medicine

PGY-4 Afanador, Andres Allport, Brandon Cueto, Victor Fischer, Hayley LoAnn, Heuring

The Brody School of Medicine at East Carolina University Baylor College of Medicine Drexel University College of Medicine The Brody School of Medicine at East Carolina University UMDNJ-New Jersey Medical School

The University of Miami Leonard M. Miller School of Medicine was founded in 1952 as the first medical school in Florida, and is acclaimed nationally and internationally for research, patient care, education and community service in the United States, South America and the Caribbean.

Serving more than five million people as the only academic medical center in South Florida, the Miller School of Medicine has earned international recognition for its patient care and research innovations.

The Miller School of Medicine campus consists of 35 acres within the 80-acre complex of the Miami Health District, including more than 2 million square feet of research space. The School of Medicine ranks in the top third among U.S. medical schools in terms of research funding awarded.

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The University of Miami Health System delivers leading-edge patient care by top-ranked physicians. Powered by the Miller School of Medicine’s groundbreaking research and medical education, UHealth provides life-saving care.

UHealth is a comprehensive network of six hospitals, two dozen outpatient facilities, 1,200 doctors, and more than 8,000 associates. As the region’s only university health system, UHealth is a vital component of the South Florida community.

University of Miami Miller School of Medicine Department of Medicine 1430 NW 11th Avenue, Suite 1001 Miami, Florida 33136 Telephone: 305-243-9120 www.med.miami.edu/medicine/