April 2015 Refill

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The monthly e-newsletter of the nationally ranked University of Toledo College of Pharmacy and Pharmaceutical Sciences

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APRIL 2015

RADM HELENA MISHOE, Ph.D., MPH, TO RECEIVE HONORARY DOCTOR OF SCIENCE PATIENT EDUCATION SAVES A LIFE A student’s intervention proves essential

PG2 ALISON WERY, BSPS ‘15 One of the college’s first cosmetic science grads takes on formulation

PG3 STUDENT LEGISLATIVE DAY Student pharmacists learn and practice policy advocacy

PG4 MEET DR. TIWARI The newest addition to the Department of Pharmacology and Experimental Therapeutics

PG5

Dr. Helena Mishoe is the associate director of Research Training and Diversity at the National Institutes of Health / National Heart, Lung and Blood Institute (NHLBI). Dr. Mishoe earned a Bachelor of Science in Biology from Delaware State University and a Master of Public Health in Health Services Administration from the Uniformed Services University School of Medicine as well as a graduate Global Health certificate from the University of North Carolina at Chapel Hill. She earned a Ph.D. in Medical Microbiology from Georgetown University School of Medicine. Dr. Mishoe joined NHLBI in 1988 and led the strategy to improve gene therapy and stem cell treatment of sickle cell anemia, Cooley’s anemia and Fanconi anemia. She has led initiatives to increase public awareness of sickle cell anemia, promote health education

in rural areas, improve and HIV treatment in Angola, among many other achievements. Dr. Mishoe’s career in research and medicine has spanned decades and includes service as the Assistant Surgeon General in the United States Public Health Service. She is an expert in health disparities and has been recognized (Continued on page 4)


“Wherever the art of medicine is loved, there is also a love of humanity. ” Hippocrates ancient Greek physician

State Board Executive Director Visits the College

PATIENT EDUCATION SAVES A LIFE By Hanin Chouman

The

College

of

Pharmacy and

Pharmaceutical Sciences welcomed Steven W. Schierholt, Esq., the Executive Director of the Ohio State Board of Pharmacy.

His career

experience includes leadership in the Ohio Attorney General’s Office, and he is a veteran of the U.S. Army. Mr. Schierholt met with college leaders to discuss many topics related to pharmacy education, including student success, international learners and the college’s unique B.S. in Pharmaceutical Sciences program. Student leaders had the opportunity to engage with Mr. Schierholt, and he gave them candid

On Friday, March 13th, 2015. Toledo SNPhA hosted a health fair at Ashland Manor, a low-income housing complex in Toledo, OH. Nine students, including six professional and three preprofessional students, participated in the health fair, providing services like education about hypertension and stroke, HIV/AIDS, kidney disease, immunization, and diabetes. Students also provided free blood pressure and blood glucose checks for participants at the health fair. The participating students helped about 50 patients, making interventions that ranged from advice about diet and exercise to asking patients to see their primary care physicians. Of particular interest on this day was a major intervention that the group made, which led to the saving of a patient’s life. When Audrey, a student, checked this patient’s blood glucose and the glucometer read ‘HI’, she called another

advice on how to reach their goals.

ALEX ADAMS, PHARM.D. ‘09, RECEIVES NATIONAL LEADERSHIP AWARD

student Akeem Bale, to help with the patient. Akeem re-checked the blood glucose and got the same reading, and after asking the patient several questions, Akeem told the patient that he needed to go to the emergency room (ER) to be seen now because his blood glucose was very high. The patient told Akeem that he was okay and didn’t need to go to the hospital; he said he was feeling okay. Akeem continued to persuade the patient about the need to go to the ER. After much persuasion and counseling, the patient agreed to go the ER, and EMS was called in to take the patient to the hospital. Several days after this major intervention the management of the housing complex reached out to the students. They we were told that the patient had suffered from a mild heart attack, and thanks to Akeem’s intervention, we saved the patient’s life. Akeem Bale is a P2 Pharm.D student, and the current president-elect of The University of Toledo’s chapter of Student National Pharmaceutical Association.

Dr. Adams is the 2015 recipient of the Albert B. Prescott Pharmacy Leadership Award from the American Pharmacists Association. The Prescott Award, given in conjunction with Phi Lambda Sigma and the Pharmacy Leadership & Education Institute, recognizes a young


DR. BRYANT-FRIEDRICH HONORED WITH ALICE H. SKEENS AWARD

Dr. Amanda Bryant-Friedrich, associate professor of medicinal chemistry and Director of International Pharmaceutical Sciences Graduate Student Recruitment and Retention, was one of five women selected for the 2015 Alice H. Skeens Outstanding Woman Award presented by the University Women’s Commission.

Students in the College of Pharmacy and Pharmaceutical Sciences earn national recognition through competitive scholarship awards and presentations at national conferences.

ALISON WERY, BSPS ‘15, EMBARKS ON A CAREER IN COSMETIC FORMULATION Alison Wery, BSPS ’14, may not realize it, but she is a pioneer. One of the first students to graduate with the nation’s only Cosmetic Science and Formulation Design bachelor’s degree, she has a unique set of skills and knowledge to apply in the cosmetic industry. Now a formulation scientist for ACT Solutions Corp., Wery’s internship experience at Earth Supplied Products, LLC. in Naples, Florida helped to establish her career path while she was still a student. “I was supposed to be working under the lab manager,” Wery said, “but I ended up being their only chemist for an entire summer. This gave me the

STUDENT AWARDS AND PRESENTATIONS

opportunity to do a little bit of everything. I made samples of raw materials like extracts and butters to send to companies. I also dealt with international and domestic shipment of samples, and I oversaw production of raw materials, technical service, organic certification, reformulation of all natural and organic lotions, creams, and scrubs, along with microreview and analysis, and stability analysis. It really influenced me to want to formulate and be in the lab. “ Wery’s work deals with contract manufac t uring, w hich incl ude s matching the formulations of products that are currently on the market with only the ingredient list as a guide. It’s like solving a mystery, one ingredient at a time. “Trying to match a product with mislabeled or missing ingredient information is difficult, especially when the client doesn't want any deviations from the ingredient listing. Also, certain (Continued on page 6)

1 NASH EARNS AFPE AWARD Kevin Nash, an Experimental Therapeutics Ph.D. earned a pre-doctoral award in pharmaceutical sciences from the American Foundation for Pharmaceutical Education. He is conducting his doctoral research in the laboratory of Dr. Zahoor Shah, associate professor in the Department of Pharmacology and Experimental Therapeutics. The award, with the purpose of supporting students who have the potential to become leaders in the pharmaceutical profession, includes a $10,000 stipend.

2 DASHP AWARD FOR CZUPRYN Michael Czupryn was one of four students in the state to earn a $1250 scholarship from the Dayton Area Society of Health-System Pharmacists.

3 PARKER TO STUDY IN JAPAN Sierra Parker, a P1 PharmD student, has earned a scholarship award from the U.S. Department of State Critical Language. The award will fund her travel to Japan this summer. Parker is the first UT student to earn this award.

4 pharmacist, no more than 10 years into his or her career, who is an emerging leader in the profession. Dr. Adams is the vice president of Foundation Programs for the National Association of Chain Drug Stores.

PHARMACOLOGY STUDENTS PRESENT AT CONFERENCE Hannah Saternos, Zahra AlOmran, Ali Zarban, and Ashraf Mohieldin, students from the lab of Dr. Wissam AbouAlaiwi, presented their research at the “Cilia, Mucus and Mucociliary Interactions” Gordon Research Conference in Galveston, TX.


“Never doubt that a small group of thoughtful, committed, citizens can change the world. Indeed, it is the only thing that ever has.” Margaret Mead Cultural anthropologist

DR. MISHOE, HONORARY DEGREE (Continued from page 1)

for her work to increase research opportunities for underrepresented students, including ethnic minorities, economically advantaged students, and students with disabilities, in the biomedical sciences. Dr. Mishoe’s leadership in advancing diversity in science, technology, engineering and math (STEM) fields is centered on her personal interest in the students she mentors. She is dedicated to student success, personally critiquing students’ presentations and grant applications as well as helping them to define their career trajectories. She oversees the NHLBI Biomedical Research Training Program for Underrepresented Groups, and a remarkable 92 percent of the participants are expected to complete terminal degrees or residencies. Among Dr. Mishoe’s treasured belongings is a photograph she received from a mentee who passed away a few years ago. The frame reads, “Hope emerges and the future begins for one person only when there is another who believes in the beauty of their dreams.” This quote reflects Dr. Mishoe’s commitment to mentoring the next generation of leaders in health care and research. Dr. Mishoe will present a seminar to the students and faculty on Friday, May 8, 2015.

STUDENT LEGISLATIVE DAY 2015 Student Pharmacy Legislative Day, an annual event organized and promoted by Ohio Pharmacists Association and the Ohio colleges of pharmacy, creates opportunities for dialog between policy makers and student pharmacists. Students learn about legislation that affects the practice of pharmacy, and they meet with legislators to discuss pharmacists’ impact on public health. In March , 10 UT student pharmacists from visited the Statehouse in Columbus to participate in this event. Their day began with seminars on audit legislation, proposed changes to the laws on immunizations, and other important legislative issues, after which they met and engaged with local legislators.

program. Student pharmacists met with State Senator Edna Brown (D-Toledo), who has shown an interest in issues related to health care and pharmacy. Following the daylong event, Senator Edna Brown (D-OH) said, “It was a pleasure meeting your students today. They were knowledgeable and engaged.” Shown above (l-r) are students Zach Henz, Kim Zitko, Shin Hae Cho, Abby Agler, Amanda Ashley, Conor Kelly, Matt Jordan, Tim Frost, Emily Kramp, Sean Hackett, along with Dr. Megan Kaun.

Students were joined by Dr. Megan Kaun, clinical associate professor of pharmacy practice and director of the PharmD Experiential Education

WELCOME, ANGELA LOPEZ, M.Ed. Angela is the college’s new Enrollment Management Specialist. She earned a B.S. in Recreation Therapy and a M.Ed. in Higher Education from The University of Toledo, and brings her experience from the UT Office of Admissions.


MEET DR. AMIT K. TIWARI Dr. Tiwari recently joined the Department of Pharmacology and Experimental Therapeutics in the College of Pharmacy and Pharmaceutical Sciences as an Assistant Professor.

THANK YOU FOR YOUR GIFT Gifts to the college support student scholarship, equipment and research. Christine Hinko

Hinko Family Fund

Angela Scardina

James A. Rice Memorial Scholarship

Susan Rice

James A. Rice Memorial Scholarship

Mary Powers

James A. Rice Memorial Scholarship

Channing Hinman

Leukemia Research Fund

Ming-Cheh Liu

Liu Fund for Drug Metabolism Research

Merck Co. Foundation

Mary Caracci Scholarship Fund

Marcia McInerney

McInerney Fund for Diabetes Research

Liyanaaratchige Tillekeratne

Medicinal & Biological Chemistry Seminar Fund

Previously, Dr. Tiwari was on the faculty at Tuskegee University in Alabama, leading a program in Cancer Pharmacology and Systems Therapeutics. Dr. Tiwari finished his MS and PhD degrees from St. Johns University, NY and later did his postdoctoral training at Mount Sinai School of Medicine in NY.

Ezdihar Hassoun

Pharmacology Fund

Diane Cappelletty

Pharmacy General Scholarship Fund

Sheryl Herner

Pharmacy General Scholarship Fund

Kenneth Alexander

Pharmacy New Lab & Equipment Tech Fund

Diane Cappelletty

Pharmacy South America Mission Fund

Hometown Pharmacy, Inc.

Pharmacy South America Mission Fund

Pfizer Foundation

Robert J. Schlembach Alumni Scholarship

Philip Miller

Robert J. Schlembach Alumni Scholarship

By using genomic analysis and pharmacokinetic/pharmacodynamics approaches, Dr. Tiwari intends to probe molecular and signaling pathways at the systems level and build quantitative models to translate these findings in improving and developing new anticancer drug developments against solid and hematological malignancies. Additionally, his research is focused on elucidating the biochemical roles of ATP-binding cassette (ABC) transporters in multi-drug resistance and tumorigenesis.

Howard Ansel

Schlembach Leadership Fund

Megan Kaun

Dr. Johnnie & Diane Early Fund Vincent and Laurie Mauro Scholarship

Frederick Williams

Williams Family Research Fund

David Waller

Andrea Kay Pavlich Memorial Award

Monica Holiday-Goodman

Dean Robert J. Schlembach Scholarship Buford T. Lively Health Disparities Scholarship

Amanda Bryant-Friedrich

Cancer Research Fund

Jeffrey Barton

Cancer Research Fund

Katherine Wall

Center for Drug Design and Development Cancer Research Support Account

James Slama

Cancer Research Support Account

Anne Feuer

College of Pharmacy Progress Fund

In addition to characterizing anticancer drug resistance, Dr. Tiwari’s work has established novel ways to reverse drug resistance and to improve cancer chemotherapeutics. He is an editor and editorial board member of number of journals and is an ad hoc reviewer of over 50 journals in the area of Pharmacology and Experimental Therapeutics.

Nancy Paserk

College of Pharmacy Progress Fund

Karleen Kinker

College of Pharmacy Progress Fund

Giant Eagle Inc.

College of Pharmacy Progress Fund

Karen Ramirez

College of Pharmacy Progress Fund

Charles Bork

College of Pharmacy Progress Fund

Kelly Holcomb

College of Pharmacy Progress Fund

Matthew Buderer

Compounding Pharmacy Fund

Pfizer Foundation

Dana S Fitzsimmons Pharmacy Scholarship

Dr. Tiwari has presented his findings at several national and international forums and conferences and has authored close to 40 peer-reviewed articles, reviews and book chapters in the last five years alone.

Jeffrey Bauer

Dean Robert J. Schlembach Scholarship

Johnnie Early

Dr. Johnnie & Diane Early Fund

Jay Mirtallo

Endowed Lab Equipment & Technology Fund Pharmacy General Scholarship Fund Pharmacy New Lab & Equipment Tech Fund


CALENDAR OF EVENTS 04.28.15 Pharmacy Law CE 7 - 8 p.m., Collier Building room 1000 Health Science Campus Register online 05.08.15 Seminar: ‘Hope for the Future: Science and Technology Embrace Equity’ 3:00 p.m. in Collier 1000A Health Science Campus Seminar by RADM Helena Mishoe, Ph.D., MPH, 2015 recipient of the honorary Doctor of Science 05.09.15 CPPS Spring Commencement Exercises 10 a.m., Savage Arena 06.05.15 Annual PharmD Preceptor Forum 9 a.m. - 1 p.m., Savage Arena, Grogan Room Register online 06.10.15 Toledo Academy of Pharmacy Golf Outing Register online 08.21.15 Professional Advancement (White Coat) Ceremony, Nitschke Auditorium, 4pm

ALISON WERY, BSPS ‘15, EMBARKS ON A CAREER IN COSMETIC FORMULATION (Continued from page 3)

ingredients don’t have to be listed on the label depending on their overall reason for use, solubilization for example. Ingredients have different forms, and figuring out which form was used can be tricky; dimethicone, for example, has different grades – 5, 10, 100. 200, 350 – all of which give slightly different textures to a lotion or cream,” Wery explained. The work is complex and challenging. Fortunately for Wery, her work is directly related to the coursework and lab experiences she had in the Cosmetic Science and Formulation Design program at UT. “Knowing what each ingredient is – emollients, surfactants, and thickeners – along with the percentage to add and manufacturing procedure are all keys to what I do on a daily basis at my job,” she said. What Wery most enjoys about her work is the success of the finished product. “It is a lot like research in that you can do something a handful of times and it might not be quite right,” Wery said, “but once you tweak things, boom! You’ve got it!” As her career progresses, Wery would like to move toward advanced formulation that includes revolutionary active ingredients, including transdermal drug delivery systems within the cosmetic field.

“A big issue in the cosmetic science industry right now is the delivery system for anti-aging ingredients and the goal of getting them into the deeper layers of skin for better results,” Wery said. “I would like to advance the research in this area.” Even as Wery moves forward in her career, she appreciates what she learned in the College of Pharmacy and Pharmaceutical Sciences. Her class notes still come in handy, too. “I still look back at them sometimes for manufacturing procedures for certain products that we made in lab and even for information about the structure and pH of the skin, hair and nails,” she said. Wery, who calls herself an “avid shopaholic,” is excited to have found a career path that blends her love of science and research with her desire to create personal care products like those she finds in her favorite highend cosmetic boutiques. As the college continues to increase enrollment in the Cosmetic Science and Formulation Design major, more graduates like Wery will redefine the many ways we improve the human condition.


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