CPPS Annual Report, FY14

College of Pharmacy and Pharmaceutical Sciences

Col l ege of Ph a rm acy a nd P h a r m ac eu t ic a l Sc i e nc e s Annual Report, Fiscal Year 2014 110 years of educating students to become pharmacists and pharmaceutical scientists while advancing pharmaceutical knowledge.

1

College of Pharmacy and Pharmaceutical Sciences

As The University of Toledo College of Pharmacy and Pharmaceutical Sciences celebrates 110 years of educating pharmacists and pharmaceutical scientists, we have the opportunity to look back on not just the most recent year, but also the efforts that have brought us here. Our college continues to engage its leaders and faculty in strategic planning and assessment that guide our progress, and the labor of emeritus deans and faculty members continues to resonate through our halls.

The world in 1904 was vastly different from the one we now face.

The founding dean and eight faculty members, who taught four learners, could not have imagined the milestones realized in 2014.

Despite the challenges of the economic and educational climates, our nationally ranked college continues to thrive. In our laboratories, faculty members are making discoveries that improve the human condition, alongside the future scientists preparing for the next generation of discovery. The practitioners who will take care of us and make us all healthier are being trained in our lecture halls and medical facilities. Indeed, the future of our college is as bright as the history of our college.

Throughout this document, you will find several Pharmacy Firsts, proving that even in a mature college, new ideas and plans come to life. I am pleased to share with you the highlights of the past year and I invite your participation in the college’s ongoing growth.

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2

College of Pharmacy and Pharmaceutical Sciences

P r e pa r i n g p r ac t i t i o n e r s Doctor of Pharmacy Program The six-year, entry-level Doctor of Pharmacy program prepares and qualifies graduates for state board licensure to practice pharmacy. The PharmD program includes professional practice development coursework and specialized experiential rotations to prepare students for practice. The course of study to obtain this degree is not static. Ongoing review and

Experiential Education in the Doctor of Pharmacy Program PharmD students receive experiential training throughout the professional division years. The experiential program consists of Introductory Pharmacy Practice Experiences (IPPE) integrated throughout the first three professional years, followed by the Advanced Pharmacy Practice Experiences (APPE) in the fourth and final professional year.

assessment informs the college on revisions to the

IPPE

curriculum.

Three hundred and eighteen students from P1, P2 and

Students applying to the PharmD professional division are now required to take the Pharmacy College Aptitude Test, which contributes to the college’s holistic review process. The composite scores for the 2014 P1 class ranged from 371-440. The fall 2014 average cumulative and science GPAs of the 108 enrolled PharmD students were 3.68 and 3.67, respectively.

Interprofessional Education The Health Science Campus colleges are implementing interprofessional education with the purpose of training students to provide better and safer patient care. Small groups composed of learners from eight different majors engage in activities at the Interprofessional Immersive Simulation Center as well as other exercises to understand the skill set and roles of each discipline and learn how coordinate each profession’s interventions on behalf of the patient. The program is utilizing the Interprofessional Educational Competencies (IPEC) core competencies.

The disciplines involved are medicine, nursing, pharmacy, physician assistant, physical therapy, respiratory therapy, occupational therapy and speech language pathology. The pharmacy team is led by Dr. Diane Cappelletty and Dr. Mike Peeters; Dr. Martin Ohlinger and Dr. Aaron Lengel are engaged in the delivery of the program.

P3 classes were placed into community, institutional and other elective IPPE experiences. Unique IPPEs include the UT Community Care Clinic, where approximately eight pharmacy students care for patients in this setting each week. The IPPE program also participates in Kroger Wellness initiatives, in which students screen patients three times each week. IPPE students are making a significant impact on the lives and health of patients in our community every day.

APPE One hundred and seven P4 students were placed into 856 individual advanced pharmacy practice experiences.

Five students were accepted through a competitive application process for longitudinal block rotations that entails four clinical rotations at the prestigious Cleveland Clinic Foundation. Four students completed medical missions as part of their APPE experiences, two each in Guatemala and Honduras.

PharmD Teaching Assistants The PharmD teaching assistant program continued, allowing the college to involve graduate-level PharmD students in teaching. This program supports the instructional capacity of the college and allows P3 and P4 students to gain teaching experience, which is helpful in their pursuit of residency training.

M a rc h 3 , 19 0 4 K ais er W ilhelm II o f G er many bec ome s t he f ir s t per s on t o make a s ound rec or ding o f a p oli t ic al do cumen t using T homa s Edis on’s cylinder.

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PharmD/PhD in Medicinal Chemistry Dual-Degree Program

Memorandum of Understanding with Professional Compounding Centers of America (PCCA)

The first PharmD/Ph.D. graduate was Dr. Fernand

In October 2013, Professional Compounding Centers

Bedi, a student in the laboratory of Dr. Amanda

of America (PCCA) signed its very first agreement

Friedrich-Bryant.

with the College of Pharmacy and Pharmaceutical Sciences. This agreement ensures that students may participate in two Introduction to Compounding courses, in May and August of each year, and gives students access to specialty compounding courses, an international seminar and rotation opportunities.

Other aspects of the agreement are PCCA formulation and stability consulting services to assist with Medical Mission projects. Employment and internship or rotations are considerations made part of the agreement for UT students. Dr. Jerry Nesamony was

T r a i n i n g p h a r m ac e u t i c a l sc i e n t i s t s Undergraduate Education The Bachelor of Science in Pharmaceutical Sciences (BSPS) degree is a four-year baccalaureate program.

The pharmaceutical sciences represent the collective basic sciences that underlie pharmacy. This degree program is designed for students who wish to pursue careers related to the pharmaceutical industry, pharmaceutical science and research, pharmaceutical

instrumental in developing this agreement.

administration and sales, the biomedical industry,

Placement of PharmD Graduates

forensic science and health care administration. It also

Practice Setting/Educational Pursuits/Undefined

prepares students to enter medical school, law school Percent

Community

50

Graduate School (i.e. MBA)

02

Institutional

or graduate studies. There are five majors under the BSPS degree program: •

Cosmetic Science and Formulation Design

•

Medicinal and Biological Chemistry

03

•

Pharmaceutics

Residency or fellowship

19

•

Pharmacology/Toxicology

Undefined at graduation

23

•

Pharmacy Administration

Other (Long Term Care, etc.)

03

A requirement of this program is a minimum 10week period of learning in a laboratory or office. This

Of a class of 101, approximately 56% of our graduates

year, 37 students were placed in 27 internship sites,

entered community practice immediately following

including two competitive Summer Undergraduate

graduation, while nearly 19% entered residency or

Research Fellowship awards and one international

fellowship training.

internship experience with the Faculty of Pharmacy,

The College actively tracks the career and post

University of Szeged, Hungary.

graduate activities of graduates through exit surveys.

The fall 2014 average cumulative and science GPAs

In 2013, the college’s passage rate among first-time

for BSPS applicants who accepted the offer of

takers of the Multistate Pharmacy Jurisprudence

admission were 3.25 and 3.18, respectively.

Examination was 96%, compared to the national average of 94.93%.

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M a rc h 5, 19 0 4 N ikola Tesla , in a public at ion c alled E lec t r ic al Wor ld and E ngineer, des cr ibes t he pr o ce s s o f t he ball ligh t ning for mat ion.

College of Pharmacy and Pharmaceutical Sciences

Cosmetic Science and Formulation Design

BSPS Scholars

The brainchild of Dr. Kenneth Alexander, the Cosmetic

The BSPS Scholar designation was coined by

Science and Formulation Design program graduated

Dr. Christine Hinko, developed through the advice

its first class in May 2014. Dr. Gabriella Baki, with the

of 2007 BSPS graduate and faculty member, Dr.

assistance of Dr. Alexander, provides instruction for

Isaac Schiefer, and implemented by Dr. James

this program. The program graduated three students:

Slama, Director of the BSPS Program. The BSPS

Sarah Breen, Kayla Banks and Alison Wery.

Scholar program recognizes highly qualified students

Combined BSPS and MS degree in Medicinal Chemistry Dr. McInerney crafted a program in which students can obtain BS and MS degrees in five calendar years. The BSPS student chooses the future MS faculty advisor as an internship mentor, continuing to the MS thesis research with the same mentor. In this approach, all requirements for both programs are fulfilled in a shortened time, and at less cost to the student. The first three BSPS/MBC students completed their

who intend to study pharmaceutical sciences and pursue graduate school or healthcare professions (dentistry, medicine, pharmacy, veterinary medicine).

BSPS Scholars engage in unique undergraduate research experiences that introduce them to the pharmaceutical sciences, and they learn leadership skills by participating in the college’s Institute for Leadership in the Sciences. In fall 2014, the first preprofessional student entered this competitive track, also earning a $300 book scholarship.

internships with their mentors in summer 2013 and started the MS portion of the combined degree in spring 2014 with the same mentors. Two new BSPS/ MS students will begin in spring 2015.

Sigma Phi Sigma Pharmaceutical Science Honor Society A seminal event in the pharmaceutical sciences was the April 30, 2014 founding, by Dr. Kenneth Alexander,

Learners from Brazil

of the Sigma Phi Sigma Pharmaceutical Science Honor Society, an honor society for students in the

The Brazil Scientific Mobility Undergraduate Program

pharmaceutical sciences. It not only recognizes

in the U.S., launched in 2011, is administered by the

the academic achievements of baccalaureate and

Institute of International Education and sponsored

graduate students in the pharmaceutical sciences, it

by the Brazilian government. 6,805 have been

is also the first such organization, and Toledo is home

placed among 302 US institutions (of 454 US

to the first chapter. Twenty-seven charter members

institutions that applied). The program is part of the

were inducted.

Brazilian government’s larger effort to grant 100,000 scholarships for the best students from Brazil to study

The Pharmaceutical Sciences Board

abroad at the world’s best universities.

As the BSPS program has matured, so has its need

Ten learners joined the BS in Pharmaceutical Sciences program in a variety of majors: pharmacology and toxicology; cosmetic science and formulation design; medicinal chemistry; pharmaceutics; and pharmacy

for its infrastructure, including a dedicated, external advisory board. The Pharmaceutical Sciences Board advises the college in regards to all pharmaceutical science majors at the BS, MS and Ph.D. levels.

administration. These students will be with the college for an academic year.

Source: Institute of International Education, Inc. http://www.iie.org/Programs/Brazil-Scientific-Mobility.

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G r a d u at e E d u c at i o n

Graduate Student Funding Source

The College of Pharmacy and Pharmaceutical

UT College of Graduate Studies

28

pharmaceutical sciences with programs in

Self-funded

8

Pharmaceutics, Medicinal Chemistry, Pharmacology/

International Government

28

Scholarship

3

programs in Medicinal Chemistry and Experimental

Fulbright

1

Therapeutics.

Fed/Industry Grant

9

Sciences offers master’s degrees in the

Toxicology, Industrial Pharmacy and Health Outcomes and Socioeconomic Sciences, along with doctoral

Ph.D. in Experimental Therapeutics Growth in Graduate Program Headcount

The Ph.D. in Experimental Therapeutics proposal, revised by Dr. William Messer, was successfully

Fall 2014 was the first semester in which graduate

approved by the Ohio Board of Regents in July

enrollment exceeded 75 students.

2012. Students were successfully recruited in the

We judge our capacity at 94 students based on faculty strength and competitive external funding.

a

Academic Year

Headcount

12-13

52

13-14

66

14-15

77a

48% increase over the steady state

Increasingly, the college is attracting graduate students from abroad, many of whom come with funding from their home governments. To address the unique needs of international graduate students, Dr. Amanda BryantFriedrich was selected as the Director of International Pharmaceutical Sciences Graduate Student Recruitment and Retention. Her role requires a heightened sense of awareness of the political and economic conditions of the countries from which international learners originate to make sure that students receive counseling and support to help them to maintain an exceptional level of academic performance.

2012-2013 academic year, and six new Experimental Therapeutics Ph.D. students matriculated in fall 2013.

An additional eight were accepted in fall 2014.

47th Annual Mid-Atlantic Graduate Student Symposium in Medicinal Chemistry (MAGSS) Medicinal Chemistry graduate students, for the first time since 2009, hosted the MAGSS at The University of Toledo. Over 110 attendees, with participation from 12 universities (Notre Dame, Univ. of Findlay, Duquesne, Univ. of Michigan, Ohio State, Cleveland State, Wayne State, Univ. of Kentucky, Case Western, Univ. of Cincinnati, Carnegie Mellon and Purdue) in addition to UT, took part in the annual event. Featured external speakers were Dr. Gordon Cragg from the NIH and Dr. Wendy Young, Director of Medicinal Chemistry from Genentech. Students presented talks and posters and attended a panel discussion on drug discovery that included speakers from the CD3 symposium.

M ay 4 , 19 0 4 T he U ni ted S t ates begins c ons t r uc t ion on t he P anama C anal.

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College of Pharmacy and Pharmaceutical Sciences

At t r ac t i n g t h e b e s t s t u d e n t s The college’s enrollment for each of its academic programs is a very good indicator of strength and

direct path to the last three years of the PharmD professional division. This year, one student entered the PharmD program through this portal.

the great desire of learners to enter careers proven to

Contingent Admission

provide a lifetime of employment in a competitive world.

Another facet of recruitment is to offer high-achieving

The college’s total enrollment, as measured by

applicants an admission pathway that bypasses

headcount as of the 15th day of the fall 2014 semester,

the application to the professional division. The

was 1,184.

Contingent Admission program received 74 applications, with 54 applicants being offered

Recruitment Methods and Programs

contingent admission and 37 of those students

Direct from High School (DHS)

enrolling. This population has the added inducement

The college has a history of filling most seats in the

of the Pharmacy Excellence Scholarship, managed

professional division of the BS in Pharmaceutical

by the Office of Enrollment Management. This four-

Sciences (BSPS) and Doctor of Pharmacy (PharmD)

year scholarship covers the full cost of tuition up to 16

programs with students directly from high school.

credit hours over four years of study.

The College-funded Enrollment Management Specialist makes a number of high school and college fair visits, including in Canada, to attract applicants.

The strategies employed are credited with stabilizing the population in the midst of new Ohio and regional pharmacy schools that have resulted in a smaller high school enrollment from which to select.

Even in a highly competitive recruitment environment in both Ohio and the surrounding states, the college continues to enroll very capable students. The average ACT score for new, first-time students was 24.7 in fall 2014, as compared to 24.9 in fall 2013. For the same 2014 cohort, the average high school GPA was 3.67, as compared to 3.60 in fall 2013.

Applicants with Undergraduate Degrees Seeking to attract learners who have earned a bachelor’s degree, the college now offers a

Toledo Early College High School BSPS Fast Track Program The BSPS Fast Track partnership with Toledo Early College High School (TECHS) allows participating sophomores to complete the undergraduate program in three years beyond the high school curriculum by taking prerequisites during the high school years. The inaugural class of four students in the TECHS BSPS Fast Track program participated in Pharmacy Camp in the summer of 2013 and enrolled in college-level biology in the past academic year. The second cohort of five students entered the program this fall. The program is designed to reduce the time to completion of the BS degree from four to three years. Each participant receives a modest book scholarship from the college.

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M ay 9, 19 0 4 T he s team lo c omo t ive, C i t y o f Tr ur o, bec omes t he f ir s t s team engine t o exceed 10 0 mph.

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College of Pharmacy and Pharmaceutical Sciences

Pharmacy Camp

R e ta i n i n g t h e b e s t s t u d e n t s

Middle School Population

Once students are enrolled in the challenging curricula of

This year, 135 students visited the Frederic and Mary

the college, the emphasis shifts to retention. The history

Wolfe Center from Glenwood, Robinson and Pickett

of the college shows the efforts of Office of Student

Middle Schools. Students participated in hands on

Affairs, staff and faculty, who are quite effective in

activities, making lotion and lip balm, listened to a panel

moving students through the program successfully. The

discussion and heard about the programs offered by

return rates for first-time, full-time students entering the

the College of Pharmacy and Pharmaceutical Sciences.

college in 2012 and 2013 and returning to UT in fall 2013 and 2014 were 80.1% and 80.6%, respectively.

High School Population Pharmacy Camp consists of two four-day camps.

Applications were received from 190 students (11% increase), including applicants from Canada, Jordan, India and Puerto Rico. In addition to labs, presentations and job shadowing, campers spent an afternoon at the Toledo Zoo, where they enjoyed a presentation from alumnus Matt Buderer, RPh, owner of Buderer Drug Company.

The average retention/graduation rate for students entering the P1 year of the PharmD class from 20022010 is 95.8%.

Health Professions Living and Learning Community Many students in the College of Pharmacy and Pharmaceutical Sciences benefit from involvement in the Health Professions Living and Learning

Eighty students were accepted to the camp and 78

Community, a cooperative venture among the

attended. Surveys continue to provide guidance

colleges of Pharmacy and Pharmaceutical Sciences,

to the College as it improves the Pharmacy Camp

Natural Sciences and Mathematics, Nursing, and

experience and its effectiveness as a recruitment tool

Health Sciences with the Office of Residence Life.

for both pharmacy and the pharmaceutical sciences.

This community entered its sixth year of operation in Carter East dormitory. Approximately 100 Pharmacy

Diversity Initiative Thanks to a continuing donation from Walgreen’s, the

freshmen moved into the HPLLC in fall 2014.

camp was able to offer $400 scholarships to a total of

Honors Program

16 students, all of whom attended the camp.

The Honors Program was active this year, with seven students graduating with Departmental Honors

IMPACT OF PHARMACY CAMP ON COLLEGE CHOICE 81%

and five students graduating with both College and Departmental Honors. Honors thesis projects are currently being pursued by undergraduate students

71%

in both the BSPS and PharmD programs. A large proportion of these students have been helped by scholarship support through Sullivan Grants and the Undergraduate Summer Research and Creative

25%

Activity Program.

During the academic year, Honors students and

2% Interested in UT

Unsure about UT

Not interested in UT

Will apply in the fall

advisors participated in events sponsored by the Jesup Scott Honors College, such as Honors Orientation for new students and Honors Thesis information sessions.

CPPS offered a variety of professional division courses for Honors credit and provided Honors Thesis opportunities to many students.

9

Thirty-three incoming freshmen registered as CPPS Honors students in Fall 2013. As is our college’s procedure, these Honors students were assigned individual advisors upon entering UT and continued to meet with the advisor regularly until graduation with either the BSPS or PharmD degree.

I n v e s t i n g i n s t u d e n t s u cc e ss Annual Giving July 1, 2014 to September 26, 2014 – Year to Date

June 30, 2013 to July 1, 2014 Total gifts

306

$162,568

82

$39,795

Total pledges

156

$53,532

14

$4,225

Phonathon gifts

27

$2,035

2

$300

Phonathon pledges

89

$6,974

12

$1,225

COUNT AND THE AVERAGE GIFT 1,200

$1,133

1,000

$794 800 $668 $567

600

$493

$471

400

FY12

200

FY13 FY14

0

Average Gift

Gift Count

TOTAL GIFTS

$534,100

600,000

500,000

0

10

Total Gifts

Alumnus/a

$176,581

$136,900

$141,433

100,000

$120,610

$126,602

200,000

$214,282

$391,806

300,000

$378,934

400,000

Corporation/Company

FY12 FY13 FY14

College of Pharmacy and Pharmaceutical Sciences

D e v e lo p i n g ta l e n t

o The recruitment and retention of a motivated, well-prepared and diverse population of

New Hires, Separations and New Appointments

students at all levels is extremely important to

Administrative Appointments

the advancement of the scientific enterprise in

•

Assistant Dean for Diversity and Community

the pharmaceutical sciences. Students with

Engagement – Dr. Monica Holiday-Goodman, RPh

origins outside our borders offer a rich source of intellect and experience to advance our

o The college is benefited by a plethora of

scientific goals. In this role, Dr. Amanda will

diversity, including racial and ethnic, gender,

provide support to those who wish to join our

national origin, language, ability, and

graduate programs from other countries from

socioeconomic differences. As the newly

their expression of interest until the awarding

appointed Assistant Dean, Dr. Holiday-

of their degrees.

Goodman will provide leadership in the planning, documentation and assessment of diversity-related efforts in support of both the college’s and University’s commitment to progression in this important area. In this capacity, Dr. Holiday-Goodman will serve as a resource to all college constituents, including students, faculty and staff and the community.

•

Division Head, Health Outcomes and Socioeconomic Sciences – Dr. Sharrel Pinto

Interim Appointments, Department of Pharmacy Practice •

Chair, Dr. Vincent Mauro

•

Vice Chair, Dr. Diane Cappelletty

New Hires •

Dr. Wissam AbouAlaiwi – Assistant Professor, Pharmacology

•

Dr. Jill Trendel – Visiting Assistant Professor, Pharmacology

•

Dr. Jeff Sarver – Visiting Assistant Professor, Pharmacology

o In her new role as Division Head for the Health Outcomes and Socioeconomic Sciences (HOSS) division, Dr. Pinto will provide leadership in strengthening the current academic programs to more accurately reflect

Separations •

Dr. William Messer – Vice President for Research, The University of Toledo

•

Dr. Steven Peseckis – Associate Dean, Jesup Scott Honors College

job market, including expanding the newly

•

Dr. Salah Ahmed – The University of Washington

established PharmD / M.S. dual-degree

•

Dr. Surya Nauli – Chapman University

•

Dr. Steven Martin – Dean, Ohio Northern University

and respond to changes in the health care fields. Dr. Pinto’s vision is that graduates have a uniquely diversified academic portfolio that allows them to compete in the current

program with aspirations for establishing a doctoral program and fellowship in Health Outcomes and Socioeconomic Sciences.

•

Chair, Pharmacology – Dr. Ezdihar Hassoun

•

Vice Chair, Pharmacology – Dr. Frederick Williams

•

Director, International Pharmaceutical Sciences Graduate Student Retention and Recruitment – Dr. Amanda Bryant-Friedrich

Promotions •

Dr. Jerry Nesamony – Associate Professor with tenure, Pharmacy Practice

•

Dr. Youssef Sari – Associate Professor with tenure, Pharmacology

•

Dr. Gabrielle Baki – Assistant Professor, Pharmacy Practice

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I n t e r n at i o n a l O u t r e ac h

Medical Missions

The College of Pharmacy and Pharmaceutical

Medical Missions continue to provide unique learning

Sciences continues its commitment to education and

opportunities for students, while contributing to global

research throughout the world. The development and

health initiatives.

engagement of our international partnerships provide educational opportunities for our students and foster research collaborations for faculty members. As a result of these partnerships, our college has a presence in many places around the world.

North Sichuan Medical College, Sichuan Province, People’s Republic of China

I m p rov i n g t h e h u m a n condition UTMC Impact Clinical Pharmacy Specialists Clinical pharmacy specialists from UTMC and faculty from the College of Pharmacy and Pharmaceutical

For the second consecutive year, the college has

Sciences provided pharmaceutical care in both the

cooperated with and the led the efforts for placement

in-patient and ambulatory care settings.

of faculty from North Sichuan Medical College in the

•

Todd Gundrum, PharmD, BCPS – Internal Medicine

•

Kellie Buschor, PharmD, BCPS – Critical Care/ Transplantation

•

Jared Austin, PharmD – Oncology (started July 1, 2014)

•

Kelli Cole, PharmD, BCPS – Infectious Diseases/ Antibiotic Steward (started Aug. 2014)

classrooms, laboratories and clinics as observers.

The college’s engagement of four visitors from North Sichuan Medical College, managed by Dr. Ming Liu shows another instance of colleges working in a collaborative manner to achieve the goal of enhancing global health initiatives.

PSG College of Pharmacy In October 2013, the college signed a definitive

College of Pharmacy and Pharmaceutical Sciences

Memorandum of Understanding that sets the

faculty members maintain active practices at UTMC

foundation for PharmD students from PSG and Sons’

for inpatient care:

Charities College of Pharmacy in Coimbatore, India to come to The University of Toledo for experiential learning. The first pair of learners arrived in fall 2013, facilitated by Dr. Jerry Nesamony.

Al Zaytoonah Private University of Jordan On January 20, 2014, the college signed a Memorandum of Understanding to formalize a collegespecific relationship that allows for student and faculty exchanges. Dr. Ghassan Abu Sheikha, Dean, Faculty of Pharmacy, was the first exchange, assigned to the laboratory of Dr. Amanda Bryant-Friedrich.

This agreement also supports the ongoing cosponsorship of the International Pharmaceutical

•

Diane Cappelletty, PharmD – Infectious Disease

•

Mariann Churchwell, PharmD, BCPS – Nephrology

•

Laurie Mauro, PharmD – Medical Critical Care

•

Vincent Mauro, PharmD – Cardiology

•

Julie Murphy, PharmD, FASHP, FCCP, BCPS – Internal Medicine

•

Martin Ohlinger, PharmD, BCPS – Surgical Critical Care

•

Michael Peeters, PharmD, MEd, BCPS – Emergency Medicine

•

Anita Ridner, PharmD – Diabetes Education

Conference by this college.

J u n e 2 , 19 0 4 P r o fes s or S chr on f inds micr obe t hat c aus es pho t o syn t hesis.

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College of Pharmacy and Pharmaceutical Sciences

J u n e 6 , 19 0 4 N at ional Tuber culo sis A s s o cia t ion is or ganized in A t lan t ic C i t y, N J. 13

Michelle N. Mangan, PharmD, RPh, BCACP, CDE, a

Clinical faculty, residents and learners

clinical assistant professor of pharmacy practice at

Clinic

Interventions per month (approximate average)

Vincent Mauro

Cardiology

400

Martin Ohlinger

Surgical ICU

225

Laurie Mauro

Medical ICU

250

Michael Peeters

Emergency Department

110

Mariann Churchwell

Nephrology

250

Julie Murphy

Internal Medicine

275

Neighborhood Family Practice

200

Clinical Faculty member

Mary Borovicka Total

1,710

UT, is program director of the outpatient diabetes education program. Dr. Michelle Mangan is the only Certified Diabetes Educator at UTMC. UTMC Diabetes Clinic A1c

Systolic BP

Diastolic BP

Baseline

9.1

132

76

Patients who came to follow up visits

8.4

128

76

Patients completing the program

7.7

126

76

Community Care Clinics The University of Toledo CommunityCare Clinics (CCC) is an interdisciplinary, student-run organization

Inpatient Education Program

established to deliver quality health care to the

A reduction in patient readmissions with in-patient

underserved populations in the Toledo Community.

education was achieved through the practices of

Triage and patient interviews are performed by

Dr. Julie Murphy and Dr. Anita Ridner.

teams of community nurse volunteers and nursing,

30-day readmission rate PRIOR to implementation of in-patient education program by pharmacy

30-day readmission rate AFTER implementation of in-patient education program by pharmacy

Diabetes

25.7%

15.5%

Heart Failure

26.4%

18.8%

Myocardial infarction

15.2%

14.0%

Disease State

14

Diabetes Education

UTMC and Neighborhood Family Practice Pharmacist Interventions

pharmacy, physician assistant and medical students to ensure thorough and comprehensive care.

Students confer with a physician preceptor who makes all decisions regarding patient care.

College of Pharmacy and Pharmaceutical Sciences

P u b l i c at i o n s, Pat e n t S u b m i ss i o n s, P o s t e r s a n d F e d e r a l R e v i e w Pa n e l S e r v i c e PLATFORM OR POSTER PRESENTATIONS

MBC

50

PHCL 87

PHPR

2

PUBLICATIONS (BOOK CHAPTERS, BOOKS OR PEER REVIEWED PAPERS)

10 MBC 32 80

PHCL PHPR

EXTRAMURAL FUNDING

$373,398 $929,771

$354,253

MBC PHCL PHPR

J u ly 2 1, 19 0 4 A f ter 13 year s, t he 4,6 07-mile Tr ansSiber ian r ailway is c omple ted.

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B oo ks, B oo k C h a p t e r s, a n d P e e r- R e v i e w e d P u b l i c at i o n s a n d M a n u sc r i p t s Department of Medicinal & Biological Chemistry 1. Trabbic, H. Dietsch, E. Alexander, P. Nagy, M. Robinson, J. Overmeyer, W. Maltese and P. Erhardt. (2014) Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-IndolylSubstituted Pyridinylpropenones. Med. Chem. Lett., 5, 73-77. Chosen for cover art by the journal.

2. Ebke LA (former*), Nestor-Kalinoski AL, Slotterbeck BD, Al-Dieri AG*, Ghosh-Lester S, Russo L, Najjar SM, von Grafenstein H, McInerney MF. (2014) Tight association between macrophages and adipocytes in obesity: implications for adipocyte preparation. Obesity 22(5) 1246-1255. PubMed Central PMCID: PMC3980195.

3. Trippier, P. C.; Zhao, K. T.; Fox, S. G.; Schiefer, I.T.; Benmohamed, R.; Moran, J.; Kirsch, D. R.; Morimoto, R. I.; Silverman, R. B., Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis. ACS Chem.

Neurosci. 2014, Article ASAP. (Based on work carried out at Northwestern University) 4. Orbán-Gyapaia, O, Raghavan*, A, Vasas, A, Forgo, A, Hohmann, J, Shah, Z.A. (2014).

Flavonoids isolated from Rumex aquaticus exhibit neuroprotective and neurorestorative properties by enhancing neurite outgrowth and synaptophysin. CNS & Neurological Disorders – Drug Targets. In Press 5. Patel, M.N, Lakkadwala, S, Majrad, M.S, Injeti, E.R, Golmer, S.M, Shah, Z.A., Boddu S.H.G, Nesamony, J. (2014) Characterization, and evaluation of 5-fluorouracil loaded solid lipid nanoparticles prepared via a temperature modulated solidification technique. AAPS Pharm.

Sci. Tech 05 (ahead of print) 6. Nada, S.E, Tulsulkar, J*, Shah, Z.A. (2014) Heme oxygenase 1-mediated neurogenesis is enhanced

by Ginkgo biloba (EGb 761) after permanent ischemic stroke in mice. Molecular neurobiology.

49:945–956. PMID: 24154866 16

7. Raghavan, A* and Shah, Z.A. (2014) Repair and regeneration properties of Ginkgo biloba after ischemic brain injury. Neuronal Regeneration Research 9(11): 1104-1107. (Invited featured perspective; article included in the popular list and figure featured on the face page) 8. Raghavan A* and Shah, Z.A.. Neurodegenerative disease. In: C. Murray Ardies (eds) Diet, Exercise, and Chronic Disease: The Biological Basis of Prevention. CRC Press, 2014. 231-252. (book chapter) 9. Keith, A. J., Kosik, S. D.+, Tillekeratne, L. M. V., Mason, Mark. R. (2014) Ion-tagged phosphines as ligands for Suzuki coupling of aryl halides in a phosphonium ionic liquid. Synlett. 25, 977-982 10. Kosik, S. D. was an undergraduate student in the Department of Medicinal and Biological Chemistry. This publication is associated with his honors thesis.

11. Ramadan A. Ali*, Tetyana Zhelay, Christopher Trabbic*, Timothy F. Walseth, James T. Slama, David R. Giovannucci, and Katherine A. Wall.

(2014) Activity of nicotinic acid substituted nicotinic acid adenine dinucleotide phosphate (NAADP) analogs in a human cell line: difference in specificity between human and sea urchin NAADP receptors. Cell Calcium, 55, 93–103.

12. Long^, P. Karmakar, K. A. Wall, and S. J. Sucheck. (2014) Synthesis of L-rhamnosyl ceramide and evaluation of its binding with anti-rhamnose antibodies. Bioorg. & Med. Chem., (in press) *Indicates graduate student ^Indicates undergraduate student +Indicates honors undergraduate student

Accepted Papers 1. Bhansali, P.*, Hanigan, C. L., Perera, L., Casero, R. A. Jr., and Tillekeratne, L.M.V. Synthesis and Biological Evaluation of Largazole Analogues with Modified Surface Recognition Cap Groups.

Submitted to Eur. J. Med. Chem. Currently under revision.

College of Pharmacy and Pharmaceutical Sciences

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Department of Pharmacology Faculty members published 32 manuscripts and had papers in peer-reviewed journals during the past academic year, while having an additional six papers in press. This number represents about a 26% increase in the number of publications listed in 2012-2013.

Particularly noteworthy is the number of papers representing collaborative efforts with departmental colleagues as well as with faculty in other departments and colleges and with other research institutions.

1. Abdul-Majeed S, Mell B, Nauli SM, Joe B.Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus.

PLoS One. 2014. 9 :e100967.

2. Jin X, Muntean BS, Aal-Aaboda MS, Duan Q, Zhou J, Nauli SM. L-type calcium channel modulates cystic kidney phenotype. Biochim Biophys Acta. 2014 1842(9):1518-26.

3. Nauli AM, Sun Y, Whittimore JD, Atyia S, Krishnaswamy G, Nauli SM. Chylomicrons produced by Caco-2 cells contained ApoB-48 with diameter of 80-200 nm. Physiol Rep. 2014. 6:2 4. Prasad RM, Jin X, Nauli SM. Biosensors (Basel)Sensing a Sensor: Identifying the Mechanosensory Function of Primary Cilia. 2014.

4:47-62.

5. Liu T, Jin X, Prasad RM, Sari Y, Nauli SM. Three types of ependymal cells with intracellular calcium oscillation are characterized by distinct cilia beating properties. J Neurosci Res. 2014.92:1199-204.

6. Kathem SH, Mohieldin AM, Abdul-Majeed S, Ismail SH, Altaei QH, Alshimmari IK, Alsaidi MM, Khammas H, Nauli AM, Joe B, Nauli SM. Ciliotherapy: a novel intervention in polycystic kidney disease. J Geriatr Cardiol. 2014.11:63-73.

7. Muntean BS, Jin X, Williams FE, Nauli SM. J Cell Physiol.Primary cilium regulates CaV1.2 expression through Wnt signaling. 2014 (in press) 8. Lakkadwala S, Nguyen S, Lawrence J, Nauli SM, Nesamony J. Physico-chemical characterisation, cytotoxic activity, and biocompatibility studies of tamoxifen-loaded solid lipid nanoparticles prepared via a temperature-modulated solidification method. J Microencapsul. 2014.

31(6):590-9.

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9. Prasad RM, Jin X, Aboualaiwi WA, Nauli SM. Real-time vascular mechanosensation through ex vivo artery perfusion. Biol Proced Online. 2014 Mar 31;16(1):6.

10. Upadhyay VS, Muntean BS, Kathem SH, Hwang JJ, Aboualaiwi WA, Nauli SM. Roles of dopamine receptor on chemosensory and mechanosensory primary cilia in renal epithelial cells. Front Physiol. 2014; 5:7211. Aboualaiwi WA, Muntean BS, Ratnam S, Joe B, Liu L, Booth RL, Rodriguez I,Herbert BS, Bacallao RL, Fruttiger M, Mak TW, Zhou J, Nauli SM. Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation. Circulation.

2014;129(6):660-72.

12. Jin X, Mohieldin AM, Muntean BS, Green JA, Shah JV, Mykytyn K, Nauli SM. Cilioplasm is a cellular compartment for calcium signaling in response to mechanical and chemical stimuli.

Cell Mol Life Sci. 2014 ;71:2165-78.

13. Nesamony J, Kalra A, Majrad MS, Boddu SH, Jung R, Williams FE, Schnapp AM, Nauli SM, Kalinoski AL. Pharm Res.Development and characterization of nanostructured mists with potential for actively targeting poorly water-soluble compounds into the lungs. 2013; 30:2625-39.

14. Nauli SM, Jin X, AbouAlaiwi WA, El-Jouni W, Su X, Zhou J.Non-motile primary cilia as fluid shear stress mechanosensors. Methods Enzymol.

2013;525:1-20.

15. Nauli AM, Nauli SM. Intestinal transport as a potential determinant of drug bioavailability. Curr Clin Pharmacol. 2013; 8:247-55.

16. Brookes ZL, Ruff L, Upadhyay VS, Huang L, Prasad S, Solanky T, Nauli SM, Ong AC.Pkd2 mesenteric vessels exhibit a primary defect in endothelium-dependent vasodilatation restored by rosiglitazone. Am J Physiol Heart Circ Physiol.

2013;304(1):H33-41.

Aug . 16 , 19 0 4 N ew Yor k C i t y begins building t he G r and C en t r al S t at ion.

College of Pharmacy and Pharmaceutical Sciences

17. Nesamony J, Zachar CL, Jung R, Williams FE, Nauli SM. Preparation, characterization, sterility validation, and in vitro cell toxicity studies of microemulsions possessing potential parenteral applications. Drug Dev Ind Pharm. 2013;39(2): 240-51.

18. Cottier KE, Fogle EM, Fox DA, Ahmed S Noxa in rheumatic diseases: present understanding and future impact. Rheumatology (Oxford). 2014. 53: 1539-1546. Epub 2013, Review 19. Jones BA, Riegsecker S, Rahman A, Beamer M, Aboualaiwi W, Khuder SA, Ahmed S. Arthritis Rheum.Role of ADAM-17, p38 MAPK, cahepsins, and the proteasome pathway in the synthesis and shedding of fractalkine/CX3 CL1 in rheumatoid arthritis. 2013, 65: 2814-25 20. Riegsecker S, Wiczynski D, Kaplan MJ, Ahmed S Potential benefits of green tea polyphenol EGCG in the prevention and treatment of vascular inflammation in rheumatoid arthritis. Life Sci. 2013, 93: 307-12 22. Rao P.S, Sari Y. Effects of ceftriaxone on chronic ethanol consumption: a potential role for xCT and GLT1 modulation of glutamate levels in male P rats.

Journal of Molecular Neuroscience, 2014, 54: 71-77.

27. Yacila G, Sari Y. Potential drugs and methods for attenuating or treating amyotrophic lateral sclerosis. Current Medicinal Chemistry (Invited), 2014 (in press) 28. Sari Y. Role of glutamate transporter 1 in the attenuation of alcohol intake. Frontiers in Neuroscience, 2014 (in press) 29. Kurogi, K., Chepak, A., Hanrahan, M.T., Liu, M.-Y., Sakakibara, Y., Suiko, M., and Liu, M.C. Sulfation of opioid drugs by human cytosolic sulfotransferases: Metabolic labeling study and enzymatic analysis. Eur. J. Pharm. Sci. 2014, 62: 40-48.

30. Hashiguchi, T., Sakakibara, Y., Shimohira, T., Kurogi, K., Yamasaki, M., Nishiyama, K., Akashi, R., Liu, M.-C., and Suiko, M. Identification of a novel flavonoid glycoside sulfotransferase in Arabidopsis thaliana. J. Biochem. 2014, 155: 91-97.

31. Kurogi, K., Liu, T.-A., Sakakibara, Y., Suiko, M., and Liu, M.-C., “The use of zebrafish as a model system for investigating the role of the SULTs in the metabolism of endogenous compounds and xenobiotics,” Drug Metab. Rev. 2013, 45: 431-440.

23. Schneider A, Sari Y. Potential trophic factors and drugs for alleviating the symptoms of Alzheimer’s disease. CNS Neurol Disord Drug Targets, 2014, 13: 909-920.

32. Nesamony J, Kalra A, Majrad MS, Boddu SH, Jung R, Williams FE, Schnapp AM, Nauli SM, Kalinoski AL. Development and characterization of nanostructured mists with potential for actively targeting poorly water-soluble compounds into the lungs. Pharm Res. 2013 ;30 :2625-39.

24. Rao P.S.S., Ahmed S, Sari Y. Effects of ceftriaxone on systemic and central expression of anti- and pro-inflammatory cytokines in alcoholpreferring (P) rats exposed to ethanol. Alcohol and Alcoholism, 2014; 49:390-398.

33. MK Greenwald, LH Lundahl, CL Steinmiller.

Yohimbine increases opioid-seeking behavior in heroin-dependent, buprenorphine-maintained individuals. Psychopharmacology. 2013, 225: 811-24.

25. Alhaddad H, Das S, Sari Y. Effects of ceftriaxone in ethanol-drinking behavior: a possible role for xCT and GLT-1 isoforms modulation of glutamate levels in P rats. Psychopharmacology, (in press)

34. MK Greenwald, DM Ledgerwood, LH Lundahl, CL Steinmiller (2014) Effect of experimental analogs of contingency management treatment on cocaine seeking behavior. Drug and Alcohol Dependence 139:164-168.

26. Rao P.S.S., Sari Y. Effectiveness of ceftriaxone treatment in preventing relapse-like drinking behavior following long-term ethanol dependence in P rats. Journal of Addiction Research and Therapy, 2014 (in press)

35. MK Greenwald, CL Steinmiller. Cocaine behavioral economics: from the naturalistic environment to the controlled laboratory setting.

Drug and Alcohol Dependence, 2014. 141:27-33. doi: 10.1016/j.drugalcdep.2014.04.028

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College of Pharmacy and Pharmaceutical Sciences

36. Wissam A. AbouAlaiwi, Brian S. Muntean, Shobha Ratnam, Robert L. Booth, Ingrid Rodriguez, Britney S. Herbert, Robert L. Bacallao, Marcus Fruttiger, Tak W. Mak, Jing Zhou, Surya M. Nauli. Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formations. Circulation. 2014; 129:660-672.

Featured in MDLinx Pharmacy and Global Medical Discovery.

37. Hassoun E, Cearfoss J, Mamada S, Al-Hassan N, Brown M, Heimberger K, Liu M. The effects of mixtures of dichroacetate and trichloroacetate on induction of oxidative stress in livers of mice after subchronic exposure. J. Toxicol. Environ. Health.

Part A, 77:313-323, 2014 38. Hassoun E, Cearfoss J. Do Antioxidant Enzymes and Glutathione Play Roles in the Induction of Additive to Greater than Additive Effects on Hepatic Oxidative Stress by Mixtures of Dichloroacetate and Trichloroacetate in Mice after Subchronic Exposure? Toxicological & Environmental Chemistry, 2014 (in press)

Department of Pharmacy Practice 1. Manik Pavan Maheswaram, Dhruthiman Mantheni, Indika Perera, Hareesha Venumuddala, Alan Riga, Kenneth Alexander, “Characterization of crystalline and amorphous content in pharmaceutical solids by dielectric thermal analysis “J Therm Anal Calorimetry, DOI 10.1007/ s10973-011-2140-2 2. É Petró, TL Paál, I Erős, AS Kenneth, G Baki, I. Csóka: Drug release from semisolid dosage forms: a comparison of two testing methods.

Pharm Dev Technol. 2013, in press, doi:10.3109/1 0837450.2013.867446 3. K. S. Alexander, G. Baki, C. Hart, C. Hejduk, S. Chillas: Comparing Suppository Mold Variability Which Can Lead to Dosage Errors for Suppositories Prepared with the Same or Different Molds. Int. J. Pharm. Compd., Nov/Dec 2013 Volume 17, Number 6 4. S. Chillas, K. S. Alexander, G. Baki: Preformulation and Evaluation of Orally Disintegrating Tablets for Pediatric Use. Int. J. Adv. Techn. Sci., 1 (1), 27-44.

5. S. Nguyen, G. Baki, J. Nesamony and S.H.S. Boddu: Vaginal drug delivery, In: Drug delivery, Edited by Ashim K. Mitra and published by Jones and Bartlett Learning, 2014, ISBN-13: 9781284025682 6. Vaidya V, Hufstader-Gabriel M, Gangan N, Shah S, Bechtol R. Utilization of smoking-cessation pharmacotherapy among chronic obstructive pulmonary disease (COPD) and lung cancer patients. Current Medical Research and Opinion.

2014; 30(6): 1043-50.

7. Pinto SL, Kumar J, Partha G, Bechtol, RA. Pharmacists-provided medication therapy management (MTM) program impacts outcomes for employees with diabetes. Popul Health Manag.

2014; 17(1): 21-7.

8. Pinto SL, Kumar J, Partha G, Bechtol, RA. Improving the economic and humanistic outcomes for diabetic patients: making a case for employer-sponsored medication therapy management. Clinicoecon Outcome Res. 2013; 5: 153-9.

9. Patel MN, Lakkadwala S, Majrad MS, Injeti ER, Gollmer SM, Shah ZA, Boddu SHS, Nesamony J. Characterization and Evaluation of 5-Fluorouracil-Loaded Solid Lipid Nanoparticles Prepared via a Temperature-Modulated Solidification Technique. AAPS PharmSciTech.

2014 Jul 18. (epub ahead of print) 10. Boddu SHS, Gupta H, Bonam SP. Preclinical evaluation of a ricinoleic acid poloxamer gel system for transdermal eyelid delivery. Int J Pharm. 2014, 15;470(1-2):158-161 11. Boddu SHS, Bonam SP, Wei Y, Alexander K. Preparation and in vitro evaluation of a pluronic lecithin organogel containing ricinoleic acid for transdermal delivery. International Journal of Pharmaceutical Compounding, 2014, 18(3): 256-261 12. Boddu SHS, Recovery of Lipophilic Drugs, Probes, AAPS Microdialysis FG Magazine.

13. Boddu SHS, Bonam SP, Jung R. Development and Characterization of a Ricinoleic acid Poloxamer Gel System for Transdermal Eyelid Delivery. Drug Delivery and Industrial Pharmacy, 2014, 1-8.

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14. Boddu SHS, Gupta H, Patel S. Drug delivery to the back of the eye following topical administration, Recent Patents On Drug Delivery & Formulation, 2014 Jan 29.

15. Nesamony J, Kalra A, Majrad MS, Boddu SHS, Jung R, Williams FE, Schnapp AM, Nauli SM, Kalinoski AL. Development and Characterization of Nanostructured Mists with Potential for Actively Targeting Poorly Water-Soluble Compounds into the Lungs. Pharm Res. 2013; 30(10):2625-39.

16. Boddu SHS, Gaudana R. Routes of drug delivery, In: Drug Delivery, Edited by Mitra AK, and published by Jones & Bartlett Learning (Date of submission: 05/2012, in print) 17. Rittenhouse K, Atluri H, Boddu SHS, Mitra AK, Microdialysis - Utility in Establishing PK/PD Relationships in Ophthalmology, In: Treatise on Ocular Drug Delivery, 2013. Bentham Science, p. 161-202 (Date of submission: Prior to 2010, Revised: 01/2013, Print: 07/2013).

18. Karla PK, Boddu SHS, Patel A, Mitra AK, Novel Strategies To Enhance Ocular Bioavailability, In: Treatise on Ocular Drug Delivery, 2013. Bentham Science, p. 140-160 (Date of submission: Prior to 2010, Print: 07/2013).

19. Rayfield A, Thomas CJ, Borovicka MC. Management of Behavioral and Psychological Symptoms of Dementia: The Role of Mood Stabilizers. Ment Health Clin. 2014;4(4):77.

Accessed August 26, 2014.

20. Cappelletty DM. Respiratory Infections.

Pharmacotherapy Principles and Practice 3rd Edition. 2012 McGraw Hill.

21. Cappelletty DM, Jacobs DM, Klochan SA. Pneumonia Case. Pharmacotherapy Principles and Practice Study Guide A Case-Based Care Plan Approach 3nd Edition. 2013 McGraw Hill.

22. Cappelletty DM, Jablonski A, Jung R. Risk factors for acute kidney injury in adult patients receiving vancomycin. Clin Drug Invest 2014;34(3):189-193.

23. Sowinski KM, Churchwell MD, Decker BS. Hemodialysis and Peritoneal Dialysis.

Pharmacotherapy: A Pathophysiologic Approach.

9th Edition McGraw Hill 2014. CH 30 p665-685. www.pharmacotherapyonline.com 22

24. Nesamony J, Kalra A, Jung R, Shah IS. “Development, physico-chemical characterization, and in vitro evaluation of nanostructured oilin-water mists for pulmonary delivery of poorly water-soluble drugs” Drug Dev Ind Pharm. 2013 25. Hoover MJ. Jung R, Jacobs DM, Peeters MJ. Validation and reliability with educational testing in the pharmacy and medical education literature.

Am J Pharm Educ 2013;77(10):article 213.

26. Taylor R, Wisneski S, Williams J, Kaun, M, et al.

Development of a Sequential APPE Experience (SAE) Program with Three Schools of Pharmacy.

Am J Health Syst Pharm. Jan 15 2014 71:140-144 27. Cain J, Congdon H, Hancock K, Kaun M, et al. Pharmacy Student Debt and Return on Investment of a Pharmacy Education. Is it worth it? Am J Pharm Educ. Feb 12, 2014; 78(1): 5.

28. Mihalopoulos CC, Powers MF, Mangan MN, Lengel AJ. Impact of a Health Literacy Training Course on Community Pharmacists’ Health Literacy Knowledge and Attitudes. J Pharm Technol. J Pharm Technol 2013; 29: 283-289.

29. Mangan MN. The timelessness of the 7 habits.

APhA Transitions. Posted July 23, 2014. Available at: http://www.pharmacist.com/timelessness-7habits 30. Mangan MN. The importance of professional development. APhA New Practitioner Blog.

Posted June 30, 2014. Available at: http://www. pharmacist.com/NewPractitionerBlog/importanceprofessional-development 31. Mangan MN. Questions every patient can ask their pharmacist. Healthy Living News Toledo: August (2014). Available at: http://www.hlntoledo. com/health-and-beauty-f/172-2014/august/630questions-every-patient-can-ask-their-pharmacist 32. Mangan MN, Shukla A. Health literacy and new roles for pharmacists. Healthy Living News Toledo: July, 13-14 (2014). Available at: http://www.hlntoledo. com/health-and-beauty-f/167-2014/july/576-healthliteracy-and-new-roles-for-pharmacists

S ept. 2 0, 19 0 4 O r ville & W ilbur Wr igh t f ly a cir cle in t heir Flyer I I

College of Pharmacy and Pharmaceutical Sciences

33. Mangan MN. UT patient advocacy program: Building a passion for advocacy. Healthy Living News Toledo: June (2014). Available at: http:// www.hlntoledo.com/our-community-2/166-2014/ june/545-ut-patient-advocacy-program-building-apassion-for-advocacy 34. Murphy JA, Doughty YA, Mangan MN. Drugs in context: liraglutide for the treatment of obesity. Formulary watch March 2014: http:// formularyjournal.modernmedicine.com/formularyjournal/news/drugs-context-liraglutide-treatmentobesity?page=full.

35. Mauro LS. Chronic Renal Failure (Online database) In: Lexi Online, LexiComp, Inc., available at: http://online.lexi.com/lco/action/doc/ retrieve/docid/patch_f/5271 36. Mauro LS. Continuous Renal Replacement Therapy. (Online database) In: Lexi Online, LexiComp, Inc., available at: http://online.lexi.com/ lco/action/doc/retrieve/docid/patch_f/196260 37. Deaton T, Mauro LS. Topiramate for pediatric migraine. Ann Pharmacother 2014;48:638-43.

38. D’Arcangelo G, Mauro VF. Guidelines for administration of cardiovascular medications with food and grapefruit juice. Pharm Pract News.

14;41(Mar): 22-5.

39. Howard MS, Boddu SHS, Mauro VF, Churchwell MD. Intravenous compatibility of conivaptan hydrochloride with select cardiovascular medications. Am J Health-syst Pharm. (in press) 40. Pitlick JM, Crannage AJ, Drew AM, Murphy JA. Development of assessments for use on advanced pharmacy practice experiences.

Currents in Pharmacy Teaching and Learning 2013;5:431-7.

41. Pearce EF, Murphy JA. Vortioxetine for the treatment of depression. Ann Pharmacother 2014;48(6):758-65.

42. Murphy JA. Ensuring effective communication with mentors and preceptors. American College of Clinical Pharmacy Resident and Fellow Newsletter August 2014: http://www.accp.com/docs/resfel/ Ensuring_Effective_Communication_with_ Mentors_and_Preceptors.pdf.

43. Meyenburg LK, Crannage AJ, Murphy JA, Korobey MJ. Evaluation of a Pharmacy-Managed Pharmacokinetic Dosing Program. J Pharm Pract 2014; (epub ahead of print) 44. Gandra SCR., Nguyen S., Nazzal SM., Alayoubi A., Jung R, and Nesamony J. 2013.

Thermoresponsive fluconazole gels for topical delivery: Rheological and mechanical properties, in vitro drug release, and anti-fungal efficacy, Pharmaceutical Development and Technology, (epub ahead of print, 10/25/13)

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O c t. 2 8 , 19 0 4 S t . L ouis p olice t r y a new inve s t igat ion me t ho d – f inger pr in t s.

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College of Pharmacy and Pharmaceutical Sciences

45. Nesamony J., Manek RV., and Kolling WM, 2014.

Evaluating the structure and dynamics of water in nanoemulsions using rheology, dynamic light scattering, and sub-ambient differential scanning calorimetry, Current Nanoscience, 10, 355-366.

46. Lakkadwala S, Nguyen S, Lawrence J, Nauli SM, Nesamony J. 2014. Physico-chemical characterization, cytotoxic activity, and biocompatibility studies of tamoxifen-loaded solid lipid nanoparticles prepared via a temperaturemodulated solidification method, Journal of Microencapsulation, 31(6), 590-599 47. Peeters MJ, Kelly CP, Cor MK. Summative evaluations when using an Objective Structured Teaching Exercise (OSTE). Am J Pharm Educ.

2014; (in press) 48. King PK, Szczerba FM, Rega PP, Peeters MJ. Interprofessional education and simulation: are we hitting the mark? Currents in Pharmacy Teaching & Learning 2014; 6(4):588-561.

54. Peeters MJ, Schmude KA, Steinmiller CL. Interrater reliability and false confidence in precision: using standard error of measurement within PharmD admissions essays rubric development.

Currents in Pharmacy Teaching & Learning. 2014; 6(2): 298-303.

55. Vaidya V, Hufstader-Gabriel M, Gangan N, Borse M. Characteristics of Prescription and Nonprescription sleep medication users in the United States. Population Health Management 56. Anthony J. Comerota, Varun Vaidya, Fedor Lurie Clinical Outcomes and Cost Effectiveness of Initial Treatment Strategies for Non-embolic Acute Limb Ischemia in Real-life Clinical Settings 57. Varun Vaidya, Sunghee Tak Song Hee Hong “Impact of patient cost sharing on medication adherence among asthmatic patients on dualcontroller therapy” Journal of Pharmaceutical Health Services Research (JPHSR) 4: 227–233. doi: 10.1111/jphs.12035

49. Peeters MJ, Beltyukova SA, Martin BA. Improving rigor in scholarship of teaching & learning: a primer on educational testing and validity of conclusions Am J Pharm Educ. 2013; 77(9); article 186. [Special Article] 50. Peeters MJ, Serres ML, Gundrum TE. Improving reliability of a residency interview process. Am J Pharm Educ. 2013; 77(8): article 168.

51. Jarab A, Murayat R, Mukattash T, Khdour M, Pinto S. “Predictors of non-adherence to pharmacotherapy in patients with type 2 diabetes,” International Journal of Clinical Pharmacy. 2014 May 8 (epub ahead of print) 52. Blazejewski L, Vaidya V, Pinto S, Gaither C. “Pharmacists’ Perceived Barriers Providing NonDispensing Services to Underserved Population,” Journal of Community Health. 2013 Oct; 38(5): 812-22.

53. Jacobs DM, Duggan JM, Sahloff EG. Gingival hypertrophy associated with amlodipine use in an HIV-infected woman. J Pharm Technol 2013;29;175-177.

Dec. 31, 19 0 4 T he f ir s t N ew Year ’s Eve celebr a t ion is held in T imes S quare, t hen k now n a s L ongacre S quare, in N ew Yor k , N ew Yor k .

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C e n t e r f o r D r u g D e s i g n (C D3) a n d D e v e lo p m e n t Despite the tough economic period and its impact upon research funding overall, the CD3 has been able to maintain much of its core operation in a functional capacity. This functionality was proven through collaborative research grants with Dr. Ron Viola (College of Natural Sciences and Mathematics) and Dr. William Maltese (College of Medicine and Life Sciences). Graduate student support was a facet of a Sponsored Research Agreement with NWO. With its leader of 20 years, Dr. Paul Erhardt, the CD3 looks forward to another year of solid productivity on several health-related research and drug development fronts.

The 20th Anniversary of the Center for Drug Design (CD3) under the Leadership of Dr. Paul Erhardt featured CD3 members and alumni and included three distinguished speakers: Dr. Christopher Lipinski, scientific advisor to Melior Discovery and a member of the American Chemical Society’s Chemistry Hall of Fame; Dr. Gunda Georg, Chair of Medicinal Chemistry at the University of Minnesota; and Dr. Mukund Chorghade, CEO of THINQ Pharma.

P h a r m ac e u t i c a l C a r e a n d O u tc o m e s R e s e a rc h ( P C OR ) L a b o r ato ry The past year was marked by developing new marketing strategies, attracting a broader array of learners and successfully acquiring Institutional Review Board approval for a multi-site study. A PCOR student is now dually enrolled in the PharmD and MS in Pharmaceutical Sciences in Health Outcomes and Socioeconomic Sciences program. Additionally, a pre-med student, a pre-professional pharmacy student and pharmacy students representing The University of Wisconsin, The University of North Carolina and The University of Mississippi have expressed interest in working on projects.

The laboratory was recognized internationally and was invited to serve as a showcase center at the World Health Economics Conference for the second consecutive year. A landmark study, led by Dr. Sharrel Pinto, Director of the Pharmaceutical Care and Outcomes (PCOR) lab, was internationally recognized on CNN and other health-related media outlets. Dr. Pinto successfully brought together leaders of various disciplines within the health care community to partner on a project that identifies a pharmacy practice model intended to improve medication adherence and patient outcomes.

Mr. and Mrs. Joseph Conda continued their generous support for the work done by students in the PCOR lab. Students who received their scholarship have presented their work at national and international conferences. A donation was received by Omnicell Inc., a leading provider of comprehensive, technologically advanced automation that enables health care facilities to acquire, manage, dispense and deliver medications and supplies more effectively.

Nov. 8 , 19 0 4 I nven t or and manu f ac t urer H ar vey H ubbell receives t he f ir s t U. S . paten t for a s epar able elec t r ic at t achmen t plug.

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College of Pharmacy and Pharmaceutical Sciences

K e y O u tc o m e s o f S ta n d i n g C o m m i t t e e s The college engages the talents and skills of its staff and faculty in the governance structure through standing committees. Important deliverables from each committee are summarized.

Academic Performance There has been a marked change in the authority of the Academic Performance committee, which is now authorized to review and adjudicate academic standards of the college. Students have the opportunity to appeal the committee decision to the dean, whose response is final and without recourse.

Assessment Actions identified for the upcoming year include the formulation of common rubrics which could be used across the graduate and undergraduate programs for common assessment such as verbal presentations and written project reports, as well as the revision of the BSPS internship evaluation to be more inclusive of programmatic learning outcomes. The committee’s work involves creating or analyzing a procedure for research projects related to curriculum and/or assessment; PharmD competencies; end-of-year and AACP graduate surveys; Pharmacy Curriculum Outcomes Assessment Exam; fall course evaluations critical thinking tests; and end-of-year exam progress.

Curriculum New PharmD program outcomes are an adaptation of the latest CAPE outcomes and are in line with the new ACPE standards. A new professional curriculum for the PharmD program is being developed. The new Interprofessional Education program, piloted in fall 2013, involved eight different professions with four students from each profession. The program was modified and implemented in fall 2014 for 555 students from eight different professions. The committee implemented online examinations in some courses with ExamSoft. A new dual-degree PharmD/M.B.A. was created and submitted for approval.

Human Diversity Three subcommittees were initiated: Social/educational activities, Speaker series, and National Observance Months, in order to enhance diversity-related information and programming provided to the College.

Information Technology The Information Technology Committee designated funding to support Computer Scholarships associated with the use of ExamSoft. Additionally, staff, supported by the Information Technology Fee, supported the use of ExamSoft.

Professional Conduct Professional division pharmacy students can be nominated by peers, faculty or staff for the CPPS Student of the Month Award every month from September through May. Nominations are reviewed by the Professional Conduct Committee members, which selects an award recipient. Recipients of the award receive a certificate presented by the Dean and Associate Dean, a photograph of the award presentation displayed on the college monitors, and lunch with the Dean and/or Associate Dean. Students nominated for this award have shown great leadership and professionalism in various college and community events.

Research, Scholarship and Graduate Education The Research, Scholarship and Graduate Education finalized a policy for CPPS concerning external review of proposals prior to submission and reviewed policies for graduate students.

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Rituals and Ceremonies The Rituals and Ceremonies Committee planned and carried out the White Coat Ceremony, Fall Convocation and Awards Ceremony and Fall and Spring Commencement ceremonies.

Scholarship The Scholarship Committee reviewed applications and essays for three separate Scholarship Award processes.

The committee prepared an essay question for applicants to complete on Scholarship Day. A total of 112 applications with essays were reviewed by the committee for 32 awards that ranged from $300 to $1500 Sixteen applications were reviewed for the 15 available Computer Scholarship awards of a $400 stipend to purchase a laptop computer for coursework. These awards were funded by the Technology Committee.

Approximately 300 internal scholarship applications were reviewed by the committee which resulted in 159 students receiving an average scholarship between $500 and $1,000 for total a total of more than $145,000.

Staff Development The Staff Development committee addressed stress reduction, improved wellness and capacity to work as a team. To accomplish this goal, the first annual Staff Retreat was planned during the 2013-14 school year and executed on July 12, 2014. The retreat hosted speakers who provided strategies for addressing the three elements of stress, wellness, and teamwork.

Pharmacy Advisory Council The Pharmacy Advisory Council updated the CPPS strategic plan 2012-2017 into Directions 2013.

The council reviewed progress or potential for interactions with six international partners.

The impact on the College of the new Accreditation Council for Pharmacy Education Draft Standards 2016 and student performance on the Pharmacy Curriculum Outcomes Assessment exam were analyzed. More guidance for students on the preparation for and use of the PCOA exam was recommended.

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PH 520 1114