Cell Cycle and Mitosis

Page 1

ROBERT PERRY – MALIBU HIGH SCHOOL


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h p o r p e s a h p meta anap hase tel op ha se

e s a

http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells2.html

MITOSIS

G2 (Gap 2)

1

M is s e n i k o t cy

2 G1 (Gap 1) G0

S-Phase (DNA SelfReplication)

THE CELL CYCLE


What is MITOSIS ? THE PROCESS BY WHICH TWO NEW NUCLEII ARE FORMED, PRECEDING CELL DIVISION.

http://fairmanstudios.com/als.htm


PURPOSE OF MITOSIS: TO PRODUCE TWO NEW NUCLEII WITH…

- EXACTLY THE SAME KIND and

- EXACTLY THE SAME NUMBER . . . OF CHROMOSOMES AS THE PARENT CELL.


http://www.dartmouth.edu/artsci/bio/cbbc/courses/bio4/bio4-lectures/theCell.html

1

2 CYTOKINESIS

MITOSIS is about organizing and distributing CHROMOSOMES


INTERPHASE

http://iccbweb.med.harvard.edu/mitchisonlab/Pages/mt.html


interphase interphase


MI TO

SIS

Biological Science, a Molecular Approach. BSCS Blue Version. Heath and Company, 1996.

INTERPHASE is the normal lifetime of a cell, after being “born” by division, and before it divides itself. INTERPHASE is not a stage of mitosis !


INTERPHASE: Gap 1 MI TO

SIS

Gap 2

Biological Science, a Molecular Approach. BSCS Blue Version. Heath and Company, 1996.

S-phase


nucleolus (if any) still visible

INTERPHASE: nuclear envelope clearly visible chromatin, NO chromosomes, yet

http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/mitosis/animal/animal_interphase.htm


INTERPHASE

Allium root tip Coregonus blastula


PROPHASE

http://www.itg.uiuc.edu/technology/atlas/structures/mitosis/prophase.htm


PROPHASE

Nuclear membrane dissolves. Nucleolus disappears. Chromosomes form. Centrioles migrate & form spindle. http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html


PROPHASE nuclear envelope disappears

nucleolus disappears http://www.ac-dijon.fr/pedago/svt/documents/mitose/prophase.gif

chromosomes become visible


PROPHASE

Allium root tip

Coregonus blastula


METAPHASE

http://iccbweb.med.harvard.edu/mitchisonlab/Pages/mt.html


METAPHASE chromatids spindle centriole

http://www.chembio.uoguelph.ca/educmat/chm736/cycletx.htm

chromatids line up on the equator.


METAPHASE T WO I D EN T I CAL COPI ES OF ON E CH ROM OSOM E.

THIS CHROMATID WILL SOON MOVE TO NORTH POLE

THIS CHROMATID WILL SOON MOVE TO SOUTH POLE

http://genenlab.spoono.com/gnu/mandm.shtml


chromatids

spindle

centriole

Nature (408. 423, 2000). http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html


METAPHASE

Allium root tip

Coregonus blastula


ANAPHASE

http://www.univ-orleans.fr/SCIENCES/BIOCHIMIE/MMC/accueil.htm


ANAPHASE chromatids migrate to each pole.

http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html


ANAPHASE early

Conly Rieder http://www.wadsworth.org/BMS/SCBlinks/WEB_MIT2/HOME.HTM

late


ANAPHASE

Allium root tip

Coregonus blastula


TELOPHASE


http://www.bmb.psu.edu/courses/bisci2/mitosis/mitosis.htm

TELOPHASE

Chromosomes dissolve. Mitotic spindle dissolves. Nuclear membrane forms. New nucleoli form.


TELOPHASE

ONE DAUGHTER NUCLEUS FORMS AT NORTH POLE SPINDLE APPARATUS DISSOLVES

ONE DAUGHTER NUCLEUS FORMS AT SOUTH POLE


TELOPHASE

early

late

New nuclei form at the poles.

Cytokinesis begins.

http://www.blc.arizona.edu/courses/181gh/Lectures_WJG.01/mitosis_F.01/mitosis.html


TELOPHASE

Allium root tip

Coregonus blastula


THE END ( CAN YOU ACE THIS QUIZ ?)


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