What signs are we seeing here? 1 · No matter what the chronological age, when the arcus senilis appears in the iris the brain is old. Arcus senilis is a cloudy opaque arc appearing over the brain area. It looks as if the sclera of the eye is actually coming down over the iris. It may be white, bluish white or have a yellow tint. To examine this sign accurately, ask the person to look down and gently lift the upper lid. · Arcus senilis, the 'arc of old age' indicates severe brain anemia. 2