IPIRA Monthly: January 2014

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JANUARY 2014

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Office Hours at IPIRA IPIRA is pleased to announce the introduction of new office hours with Errol Arkilic and Rob Schock.

IPIRA manages UC Berkeley's

SBIR / STTR Office Hours SBIR/STTR advice and funding for small businesses

and student scientists. We aim to provide

Errol Arkilic is a former NSF SBIR Program Manager and the founding Innovation Corps (I-Corps) Lead Program Director. Errol spent ten years at NSF, eight as a program director leading the Software and Services and Security (Nano/Bio/IT) Technology portfolios. Errol has personally reviewed approximately 1,000 SBIR/STTR proposals.

Students seeking mentoring for SBIR/STTR grant applications are

intellectual property portfolio, based upon inventions created by our stellar faculty value­added services to Berkeley's research community through the out­ licensing of Berkeley's innovations, facilitation of industry research dollars, and patent drafting services, among educational programs and industry partnered events.

encouraged to sign up.

Build Your Financial Model Office Hours Build your financial model ­ for small businesses

New Technologies

Rob Schock will be hosting office hours on "Build Your Financial Model ­

Thinking Big with NanoLab

For Small Businesses". Rob is a serial Chief Financial Officer with over

Caribou Biosciences' Co­

three decades of senior management experience. This workshop is

Founder on '30 under 30'

intended for student entrepreneurs and researchers interested in expert

Genocea Files for $75M IPO

advice on financial models and financing alternatives for startups and

Berkeley Research Named

small businesses.

Breakthrough of the Year

All appointments will be honored on a first­come, first­serve basis. Email ipira@berkeley.edu to sign up.

Grants Luncheon UC Tech Transfer Forum View entire newsletter for more

Interested in more events? Check out our EVENTS page at

Intellectual Property Announcements,

ipira.berkeley.edu/events.

Researcher Toolbox, Portfolio Startup

You are also invited to find us on

News, and Recommended IPIRA and Community Events.

New Berkeley Technologies Released for Licensing

Engineering & Physical Sciences Durable Carbon­Coated Materials and Methods for High Performance Lithium / Sulfur Cells 2014-114 Applications in next generation lithium battery cells, electric vehicles, unmanned aerial vehicles, electronics

GREEN: An Ultra­Small, Wireless Sensor Platform 2014­043 Applications in smart grid, wireless sensing devices

Josephson Junction Transmission Line Parametric Amplifier 2014­096 Applications in quantum computing, satellite-based communications, astrophysics research

Redox­Active Metal­Organic Frameworks for the Catalytic Oxidation of Hydrocarbons 2014­098 Applications in chemical and natural gas processing, green energy

Single­Cell Forensic Short Tandem Repeat Typing within Microfluidic Droplets 2014­085 Applications in short tandem repeat (STR) typing for human forensic identification

Three­Dimensional Differential Phase Contrast Imaging By Computational Illumination 2014­108 Applications in 3D microscopy, medical imaging

Software Video Stabilization Software 2014­088 Image stabilization, video processing, Photoshop and visual effects

Healthcare Compositions and Methods and for Isolating Rare Cell populations Based on Gene Expression 2014­022 Applications in microbial sorting, pathogen diagnosis, Magnetic Activated Cell Sorting (MACS)

Flexible Parylene Integrated Photonics 2014­054 Applications in brain-machine interface, neural stimulation, guided surgery, cancer diagnostic

Flexible Wound Healing Monitor 2014­059 Applications in internal wound monitoring, pressure ulcer prevention, granular tissue detection

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Visit IPIRA's website at http://techtransfer.universityofcalifornia.edu/default.aspx?campus=BK to explore all Berkeley innovations and ways to collaborate with the University.

Patent Awards between December 2013 and January 2014

Fabricated Adhesive Microstructures for Making an Electrical Connection 2004­018 Applications in integrated circuits and consumer electronics Patent Number: 8,610,290. Inventors: Autumn, et al. Status: Available for Licensing.

Integrated Magnetic Field Generation and Detection Platform 2008­015 Applications in POC diagnostics, environmental assays Patent Number: 8,614,572. Inventors: Florescu et al. Status: Available for Licensing.

Optoelectronic Tweezers for Microparticle and Cell Manipulation 2004­E93 Patent Number: RE44,711. Inventors: Wu et al. Status: Licensed.

Volumetric Induction Phase Shift Detection for Determining Tissue Water Content Properties 2005­097 Patent Number: 8,633,033. Inventors: Rubinsky et al. Status: Licensed.

Research and Entrepreneur Toolkit

Thinking big about small things? NanoLab may be right for you The UC Berkeley Marvell Nanofabrication Laboratory (The NanoLab) is a campus resource serving the research needs of over 90 faculty and almost 500 graduate and post graduate researchers. The NanoLab is a shared nanotechnology laboratory supporting more than 170 pieces of micro/nanofabrication and metrology equipment in a 15,000 square foot clean room.

NanoLab provides access to this university cleanroom and enables use of the lab’s specialized academic research equipment by industrial and commercial researchers via the Berkeley NanoLab Affiliates (BNLA) Program. Since 1995, over 100 local high technology companies, many of them university startups have used the BNLA program to launch their development efforts. Venture capital and angel investors often encourage their clients to initiate laboratory work in already established research facilities to minimize upfront capital costs while early development milestones are met.

Researchers from the private sector, national labs (including Sandia and Lawrence Livermore), and non­academic organizations are eligible to apply for affiliate membership. A yearly commitment is required. For more information, contact Executive Director Dr. Bill Flounders (bill@eecs.berkeley.edu) or visit the Berkeley NanoLab website at http://nanolab.berkeley.edu.

Tandem is now accepting applications until March 1, 2014 Tandem is a mobile industry accelerator, awarding $200,000 seed investment to each individual company. Portfolio companies include Playhaven, UpOut, UC alumni­founded Parkify, and PagerDuty which has been adopted by Airbnb, Instagram, GitHub, Harvard, Box, Evernote and more. PagerDuty raised a $10.7M in Series A round from Andreessen Horowitz this month. [application]

Use Pivot to access and keep track of global research funding and collaboration opportunities Pivot is available to the Berkeley campus community and combines the most comprehensive, editorially maintained database of funding opportunities worth an estimated $33 billion with a unique database of 3 million scholar profiles, and growing.

Office and Portfolio Startup News

Co­Founder of Caribou Biosciences listed on 2013 Forbes’s ’30 under 30′ list Rachel Haurwitz obtained her Ph.D. at Berkeley under Jennifer Doudna's lab in 2012 where the revolutionary gene engineering technique CIRSPR was discovered. After seeing the new Cas9 technology's potential, Haurwitz cofounded Caribou Biosciences, where she is President and CEO. ['30 under 30' list]

Genocea Biosciences files for $75 million IPO Genocea is able to identify protective T cell antigens in humans exposed to a pathogen and thus enable new vaccine solutions using ATLAS™, its proprietary discovery platform developed by scientific founder Dr. Darren Higgins while he was at Berkeley. Genocea holds an exclusive license from Berkeley to the first patent family, including U.S. Patent 6,004,815 and related U.S. Patents 6,287,556 and 6,599,502, which cover claims to fundamental aspects of ATLAS™. [news] [S­1 filing]

Ekso Bionics completes reverse merger, raises $20.6M Esko Bionics completed an alternative public offering on January 15, 2014, simultaneously raising $20.6 million in private placement. The company commercializes innovative exoskeletons, or wearable robots, to enable individuals to achieve mobility, strength, or endurance not otherwise possible, and to help people living with paralysis to stand and walk again. Ekso signed a cross­licensing agreement with Lockheed Martin in July 2013. [press release] [see Esko's CES 2014 video demo]

Amyris announces $28M private placement Amyris sells senior convertible promissory notes to major stockholder, Temasek, in conjunction with new investors affiliated with Wolverine Asset Management. The private placement is expected to raise $28 million in cash proceeds. [press release]

IPIRA led sponsored research agreement between Bosch and UC Berkeley Robert Bosch LLC (Bosch) has entered into Sponsored Research Agreements with University of California Berkeley’s Departments of Chemical Engineering and Chemistry, expanding the company’s research and development efforts in advanced energy materials. Under the agreements, Bosch will work with Dr. Elton Cairns and Dr. Jeffrey Long on separate projects to advance the development of next generation lithium cells. Discovering new rechargeable battery materials and systems are of considerable technological importance because of the increasing demands for reliable, compact and affordable energy storage, from electric cars and backup power systems to implantable medical devices and consumer electronics. The advanced research at UC Berkeley seeks to help double the energy density, improve cell performance under extreme conditions, and scale up to larger cells. [more inventions by Dr. Elton Cairns] [more inventions by Dr. Jeffrey Long]

Berkeley's Exo­skeleton selected for 2014 AUTM "Put a Face on It" video project AUTM's "Put a Face on It" video project aims to put a face on technology transfer and to highlight government­funded research that culminated in life­saving cures for diseases and products that make a profound impact on society. The 2­minute video features the end user of Ekso and will be displayed at the February 2014 AUTM Annual Meeting and beyond.

Berkeley Affiliate News

Science magazine named Berkeley's cancer immunotherapy Breakthrough of the Year for 2013 The discovery emerged from work conducted by UC Berkeley immunologist James Allison in the 1990s. It paved the way for other immunotherapies now undergoing clinical trials. Results published in 2013 provided very encouraging results for kidney, lung, prostate and metastatic cancer patients. [news] Photo by: Jane Scherr.

A cancer pioneer, James Allison's seminal invention was patented by Berkeley and managed by IPIRA. Under the license, Allison's research led to the first­in­class treatment for Phase IV melanoma (YERVOY ® by Bristol­Myers Squibb) to be approved by the FDA and the first drug ever to improve the survival rate of metastatic melanoma patients. The license generated an upfront payment of $87.5 million for Berkeley with the possibility of two additional milestone payments. Funds were directed to build Berkeley undergraduate biology teaching labs, improvements and research equipment for Berkeley's Cancer Research Laboratory (CRL), and other scientific research needs from funding graduate student support, faculty retention, to portions of a new Berkeley Stem Cell Center.

Science magazine named 2012 Berkeley discovery runner­up for 2013 Breakthrough of the Year The gene­editing technique, CRISPR, allows very precise manipulation of genes and may make gene therapy a realistic alternative for patients. It has seen more than 50 publications in 2013, with one CRISPR “how­to” website attracting about 900 visitors each day. The technique was discovered by Jennifer Doudna and Martin Jinek of the Howard Hughes Medical Institute at UC Berkeley and Emmanuelle Charpentier of the Laboratory for Molecular Infection Medicine­Sweden, with genetic diseases. [Doudna's story]

Bioengineering professors receive $500,000 Keck Fund award Kumar and Murthy’s research aims to develop an enzyme­linked immunosorbent assay (ELISA) platform to identify the proteomic “fingerprints” that predict key clinical features of the incurable brain tumor glioblastoma multiforme. [news]

Berkeley research team invented smart light-activated curtains The discovery could enable photo-reactive curtains and other materials to move in response to light, with energy-efficient applications. The research team is led by Ali Javey, associate professor of electrical engineering and computer sciences. [news]

Berkeley moves up to third in ARWU’s 2013 global rankings Berkeley moved up to third place behind Harvard and Stanford in the 2013 Academic Ranking of World Universities (ARWU) global rankings of universities. Fourth­place ranking is now held by MIT. [news]

Events

Grants and Contracts, and More, at UC Berkeley: An Introduction Using “Speed Networking” (Sponsored by The Vice Chancellor for Research) February 11, 2014

New UC Berkeley faculty members have much to do and little time to do it. The Vice Chancellor for Research is therefore sponsoring an informal luncheon and information session (in speed dating format) designed to give all faculty and non­faculty principal investigators who have been at UC Berkeley three year or less a chance to quickly learn about the services provided by the various central campus offices that assist faculty with grants and contracts and some other aspects of research administration.

Date and Time: February 11, 2014, 12:00 ­ 1:30 pm Lunch/Meeting Location: Heyns Room, Faculty Club RSVP Required (space is limited) Attend this meeting and you will find out: How you can find external funding opportunities and stay up­to­date on new funding initiatives Where you can go to get help with everything from basic grant writing to the coordination of large multidisciplinary and multi­institutional projects How you can effectively navigate the many compliance requirements that impact your research How you can protect and transfer your intellectual property “Who does what” at UC Berkeley from pre award proposal development through grant close out Participating Offices/Committees: Berkeley Research Development Office Intellectual Property and Industry Research Alliances

Industry Alliance Office Office of Technology Licensing Research Administration and Compliance Sponsored Projects Office Office for Animal Care and Use Office for Protection of Human Subjects Research Conflict of Interest Office If you have any questions about the program, please contact Leah Esturas­Pierson at: lrpierson@berkeley.edu or (510) 642­5829.

Annual University of California Technology Transfer Forum May 8, 2014

The University of Technology Transfer Forum is organized by the University of California Office of the President and showcases technology innovations from across the UC system. The annual Forum brings together industry partners, investors and UC researchers to showcase commercially relevant UC research; discover potential investments; preview promising licensing opportunities; and explore new collaborations.

This year's event will highlight the work of UC's 2013 Proof­of­Concept Commercialization gap grant recipients. 2013 Berkeley projects include: Low­Cost Arsenic Remediation for California Groundwater, Ashok Gadgil Noise Reduction for Hearing Aids, Frederic Theunissen

Save the Date for NSF SBIR/STTR Grant Application Bootcamp May, 2014

Presenter: Shauna Farr­Jones Location: UC Berkeley, Stanley Hall, Room 117 Schedule: Two 2.5­hour classes

Office Hours

SBIR / STTR Office Hours Errol Arkilic is the Founder and President of USRCA.org. Founded in June of 2013, this organization's mission is to support the translation of academic­based research into products and services that address significant market needs. Previously, he was the founding and lead program director for the National Science Foundation Innovation Corps program. He led the I­Corps effort from its inception until July 2013.

Prior to this, Errol was the lead software and services program director for the NSF SBIR program. Before NSF, Errol was founder and CEO at StrataGent Lifesciences and the Manager of Product Engineering at Redwood Microsystems. Errol received his BS in Mechanical Engineering from George Washington University and his Master's and Ph.D. degrees in Aero/Astro Engineering from MIT.

Location: 2150 Shattuck Avenue, Suite 1000, Berkeley, CA Date: 1st Thursday each month Time: 4:00 pm ­ 5:30 pm

Build Your Financial Model Office Hours Rob Schock is a finance specialist with over 30 years of senior management experience. His experience spans Fortune 100 companies to Silicon Valley start­ups. As Chief Financial Officer, Rob has installed management control systems, created business models, run accounting departments, designed compensation programs, and managed investor, bank and auditor relationships. Rob is currently a part­time Chief Financial Officer at Picture Marketing, a marketing company on the list of Bay Area 100 fastest growing companies for two years, and a founding member of the Venture Consulting Group (“VCG”), a network of executives providing consulting and management services to early stage and emerging technology companies. Rob has served as a mentor for Keiretsu Entrepreneur Academy, and UC Berkeley Haas Business School’s and UC Davis Business School's Annual Business Plan Competitions.

Location: 2150 Shattuck Avenue, Suite 1000, Berkeley, CA Date: 1st Monday each month beginning March 2014 Time: 3:30 pm ­ 5:00 pm Know someone who might benefit from our newsletter? Share it!

Please send any correspondence and content suggestion to ipira@berkeley.edu.

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