Innovation dans le suivi thérapeutique des patients BusiNETvs Dr. Jean-Michel Métry CEO, AARDEX Group (CH)
BusiNETvs, Sierre, May 28th, 2009
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MEMS I 1987
BusiNETvs, Sierre, May 28th, 2009
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Breaking the downward spiral
BusiNETvs, Sierre, May 28th, 2009
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MEMS system Medication Event Monitoring System (MEMS速)
Events recording and storage
MEMS速 6 BusiNETvs, Sierre, May 28th, 2009
Communication device
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Internet
www.viewcompliance.com
Aardex Group products & strengths
Basic feedback to the patient Nothing
INFORMATION
Number of openings during the day Time since last dose taken Compliance index
BusiNETvs, Sierre, May 28th, 2009
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MEMS 7
BusiNETvs, Sierre, May 28th, 2009
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SCL Detection scheme
Mechanical action
Contact between 2 conductive layers
Manipulation
Signal detection
Prototype Noise BusiNETvs, Sierre, May 28th, 2009
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Pill out
SCL: development status
BusiNETvs, Sierre, May 28th, 2009
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Research prototype 2009
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Technology platform
New IP
CORE IP AARDEX Group BusiNETvs, Sierre, May 28th, 2009
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Innovation and taxonomy
Non acceptance 1.0
Perfect adherence
0.8 0.7 0.4
0.5
0.6
Percent
0.9
Treatment discontinuation
0
100
200
Days Source: AARDEX (Pharmionic database)
BusiNETvs, Sierre, May 28th, 2009
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300
PKC: N ~ 20,000 patients
Innovation and regulation: EU-ABC project
BusiNETvs, Sierre, May 28th, 2009
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Innovation and networking iAdherence
Research community
Heathcare systems & Drug regulators
Insurers
Pharma industry
Health care providers End users
Physician Pharmacist Nurse
Patients Families Patients associations
BusiNETvs, Sierre, May 28th, 2009
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B. Vrijens, Feb 2008
Innovation and communication
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Innovation and publication
BusiNETvs, Sierre, May 28th, 2009
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Innovation and positioning
AAG Unique position
BusiNETvs, Sierre, May 28th, 2009
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Innovation: competitor analysis Identification of current and future competitors MWV & Stora Enso (e-blister) B & OM (Bang & Olufsen Medicom Helping Hand device) GlowCap (new in the market with a simple concept) e-Pill pure gadget company
Competitor Positioning Map (considering relevant variables)
Information AAG
B & OM
MWV
As low as possible CoG Maximum information
Strora Enso Price e-Pill
GlowCap
Innovation axis BusiNETvs, Sierre, May 28th, 2009
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Innovation: modelling and simulation Validation: Cutoff criteria (based on the ROC Curve): 0.1 Number of neighbours: 20
Persistent
Predicted based on the algorithm
Non Persistent
Sensitivity: 79% Specificity: 62% Positive Predictive Value: 29% Negative Predictive Value: 94%
BusiNETvs, Sierre, May 28th, 2009
Actual Observation
Persistent
Non Persistent
106 (62%) (94%)
7 (21%) (6%)
65 (38%) (71%)
27 (79%) (29%)
171 (100%)
34 (100%)
113 (100%) 92 (100%) 205
Poor executers: it’s good to intervene anyway Good executers: it’s difficult to predict their non-persistence based on their quality of executions
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Innovation and new business model Business Models
–
•
What & Why: product and value proposition EM and modeling and/or simulation for the CT and intervention for the broader market with medAmigo intervention
•
Where: target groups/customers and possible market segments From the pharmaceutical companies to the patients including third party payers, patients’ organizations,…
•
How: possible strategy for market entry and positioning Large pharma launch for new products and/or re-launch of existing products with innovative interactive packaging concept.
•
Who: position in the value network and necessary partnerships Mostly be the end user who is, in our case the patient
•
How to deliver: internal value chains and market distribution channel Via our existing channels and potentially new partners
•
How much: cost structures and revenue generation mechanism For every dollar spent at least one back
BusiNETvs, Sierre, May 28th, 2009
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Innovation and market opportunities
Innovation and market potential Clinical trial market (measurement no intervention) Target customers: Pharmaceutical companies Users: Health care professionals and patients
BusiNETvs, Sierre, May 28th, 2009
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Innovation and evolution (cycles) 3.2 Interventional market (medAmigo intervention) Target customers: Pharmaceutical companies, insurers,‌ Users: Health care professionals to patients
Market potential In US$ is going to be billions of US$
BusiNETvs, Sierre, May 28th, 2009
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THANK YOU! BusiNETvs, Sierre, May 28th, 2009
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