BIOMIMETIC LOZENGE ​AND LASER DIODE THERAPY

BIOMIMETIC LOZENGE AND LASER DIODE THERAPY: Fast and Long-term Efficacy in Managing Dentinal Hypersensitivity

Traditional Methods of Treating DH Symptoms

Desensitizing dentifrices

Fluoride

Surgical gum graft

Bonding

Restorative Dentistry

What’s new?

Laser Diode Therapy

Biomimetic Repair Via Remineralizing Lozenges

LASER DIODE What is laser diode?

How effective is it?

Diode laser delivers energy in the form of light of wavelength ,ranging from 660 nm to 1064nm.

Clinical studies show an immediate reduction of pain after treatment.

Diode laser act directly on cellular structure, destroying cells walls, modifying metabolic processes and structure of the biofilm.

For treatment of dentinal hypersensitivity, diode laser will melt the dentin structure.

Different wavelength (660nm , 810nm, 910nm) with different power beam setting (from 30 to 100 mW) were used to show effectiveness.

Pain scores show that the effect of 910 nm diode laser has a long term lasting effect compared to smaller wavelength.

(El Mobadder et al., 2019)

Advantages and Disadvantages of Laser Diode Therapy • Less invasive • Less bleeding • Wide range of procedures such as treatment of oral ulcer, frenectomy, antimicrobial effect, enhance osteointegration for implant • Improvement of clinical attachment • Less pain and patient compliance and acceptance • Reduction of post-operative drugs • Fast healing

• Multiple session needed • May damage pulp at higher temperature • Contraindicated for primary teeth root canal • Require eye protection • Certain procedure may involve unpleasant smell.

• Expertise and training necessary

NOT your ordinary lozenge!

This biomimetic treatment used a mineralizationdirecting peptide called sADP5, derived from amelogenin, to promote dentin repair. sADP5 can be integrated into any type of oral health product, such as a lozenge the size of cough drop.

(Yucesoy et al., 2023)

(Yucesoy et al., 2023)

BIOMIMETIC LOZENGE CHEMICAL, MECHANICAL, AND THERMAL PROPERTIES

(Yucesoy et al., 2023)

• Hardness value and elastic modulus of new mineral layer shows higher values vs. sound dentin.

(Yucesoy et al., 2023)

• Full integration and continuity of the mineral layer is preserved after exposing it to hot, cold stimuli. No change has been observed in the chemical composition.

Conclusions Laser Diode • Some traditional desensitizer has a non

Biomimetic Lozenge • Peptide-guided remineralization shows promise in

immediate, temporary and short-term effect

restoring and safeguarding exposed dentin, creating a

due to wear off the material or interruption of

stable mineral layer with favorable mechanical and

the treatment.

thermal properties.

• Diode laser alone shows long term efficacy in

• Benefits include non-invasiveness, user-friendly

treating dentinal hypersensitivity with an

application, exclusive capability for fortifying and

immediate decrease of pain.

rebuilding enamel, and comprehensive coverage of

• The combination of diode laser and traditional desensitizer may increase effectiveness and

dentinal tubules.

• Drawbacks include incomplete testing in the human

long-term lasting efficacy of dentinal

mouth, limited evidence-based information, early trial

hypersensitivity.

stages, uncertain long-term performance, unknown costs, and potential delays in full dentin accumulation.

REFERENCES El Mobadder, M., Namour, A., Namour, M., Dib, W., El Mobadder, W., Maalouf, E., Geerts, S., Zeinoun, T., & Nammour, S. (2019).

Dentinal hypersensitivity treatment using diode laser 980 NM: In vivo study. Dentistry Journal, 7(1), 5. https://doi.org/10.3390/dj7010005

Joy Raskie, R. (2023, March 31). Utilizing a diode laser in dental hygiene practice. Registered Dental Hygienists. https://www.rdhmag.com/patient-care/lasers/article/14179004/utilizing-a-diode-laser-in-dental-hygiene-practice Kornegay, E. C. (2020, June 23). Dentinal hypersensitivity diagnosis - dimensions of dental hygiene: Magazine. Dimensions of Dental Hygiene | Magazine - Dental Hygiene Magazine for RDH’s. https://dimensionsofdentalhygiene.com/article/dentinalhypersensitivity-diagnosis-ce/ Malcangi, G., Patano, A., Trilli, I., Piras, F., Ciocia, A. M., Inchingolo, A. D., Mancini, A., Hazballa, D., Di Venere, D., Inchingolo, F., de Ruvo, E., Dipalma, G., & Inchingolo, A. M. (2023). Therapeutic and adverse effects of lasers in Dentistry: A systematic review.

Photonics, 10(6), 650. https://doi.org/10.3390/photonics10060650

Naghsh, N., Kachuie, M., Kachuie, M., & Birang, R. (2020). Evaluation of the effects of 660-nm and 810-nm low-level diode lasers on the treatment of dentin hypersensitivity. Journal of Lasers in Medical Sciences, 11(2), 126– 134. https://doi.org/10.34172/jlms.2020.22 Yucesoy, D. T., Fong, H., Hamann, J., Hall, E., Dogan, S., & Sarikaya, M. (2023). Biomimetic dentin repair: Amelogenin-derived peptide guides occlusion and peritubular mineralization of human teeth. ACS Biomaterials Science & Engineering, 9(3), 1486–1495. https://doi.org/10.1021/acsbiomaterials.2c01039

Goal and Objectives GOAL To educate dental and other healthcare professionals about the most recent methods and innovations in treating dental hypersensitivity.

OBJECTIVES • Identify the latest methods in treating dental hypersensitivity and describe their main functional components and targets.

• Assess the immediate efficacy of laser diode therapy in providing fast relief from dentinal hypersensitivity by measuring patient's pain scores before and after treatment.

• Assess the efficacy of biomimetic lozenge by measuring the chemical, mechanical and thermal properties before and after "treatment".

• Identify the advantages and disadvantages of using biomimetic lozenge and laser diode therapy in treating dentinal hypersensitivity.

• Compare the efficacy of biomimetic lozenge and laser diode therapy with traditional treatments for dentinal hypersensitivity such as desensitizing dentifrices, in terms of short and long-term relief.