Cat. No. LPS 003-SA
(50μl)
Cat. No. LPS 003-A
(100μl)
NEW Pathology Probes Probe Name
Chromosome Region
Probe Type
1p36
1p36.32
1q25
Probe Specification EGFR, 7p11.2, Red D7Z1, 7p11.1-q11.1, Green
19q13
The EGFR Amplification probe consists of a red 295kb probe spanning the gene region 7p11.2. The centromeric probe in green acts as a control for chromosome 7.
EGFR Amplification
D7Z1
7p11.2
Control Probe
Volume (μl)
Cat. No.*
–
–
25 or 50
LPS 513-A
1q25.2
–
–
25 or 50
LPS 512-A
19q13.33
–
–
25 or 50
LPS 516-A
19p13
19p13.2
–
–
25 or 50
LPS 515-A
RET Proximal
10q11.21
–
–
25 or 50
LPS 508-A
RET Distal
10q11.21
–
–
25 or 50
LPS 509-A
ROS1-GOPC(FIG) Proximal
6q22.1
–
–
25 or 50
LPS 510-A
ROS1-GOPC(FIG) Distal
6q22.1
–
–
25 or 50
LPS 511-A
Control Probe
Volume (μl)
Cat. No.*
–
50 or 100
LPS 019-A
Pathology Probe Range Probe Name
Chromosome Region
Probe Type
ALK
2p23.2-p23.1
Breakapart
CHOP (DDIT3)
12q13.3
Breakapart
–
50 or 100
LPS 015-A
C-MET (MET)
7q31.2
Amplification
D7Z1
50 or 100
LPS 004-A
EGFR
7p11.2
Amplification
D7Z1
50 or 100
LPS 003-A
ERG
21q22.13-q22.2
Control
–
25 or 50
LPS 099-A
EML4
2p21
Breakapart
–
50 or 100
LPS 020-A
EWSR1
22q12.1-q12.2
Breakapart
–
50 or 100
LPS 006-A
EWSR1/ERG Dual Fusion
21q22.13-q22.2/22q12.1-q12.2
Translocation
FGFR1
8p11.23-p11.22
Breakapart/Amplification
(50μl)
FLI1/EWSR1 Dual Fusion
11q24.3/22q12.1-q12.2
(100μl)
HER2 (ERBB2)
17q12
EML4 Breakapart
MALT1
EGFR D7S793
D7S2357
D7S1988
D7S2935
295kb 100kb
–
50 or 100
LPS 008-A
D8Z2
50 or 100
LPS 018-A
Translocation
–
50 or 100
LPS 007-A
Amplification
–
50 or 100
LPS 001-A
18q21.31-q21.32
Breakapart
–
50 or 100
LPS 017-A
MDM2
12q15
Amplification
D12Z1
50 or 100
LPS 016-A
N-MYC (MYCN)
2p34.3/2q11.2
Amplification
AFF3 (2q11.2)
50 or 100
LPS 009-A
Probe Specification EML4, 2p21, Red EML4, 2p21, Green
PAX3
2q36.1
Breakapart
–
50 or 100
LPS 012-A
PAX7
1p36.13
Breakapart
–
50 or 100
LPS 013-A
The EML4 Breakapart probe consists of a green 406kb probe and a red 353kb probe, which are positioned on each side of the EML4 gene.
RB1
13q14.2
Deletion
13qter
50 or 100
LPS 011-A
ROS1
6q22.1
Breakapart
–
50 or 100
LPS 022-A
SRD (CHD5)
1p36.31
Deletion
1qter
50 or 100
LPS 010-A
SYT (SS18)
18q11.2
Breakapart
–
50 or 100
LPS 014-A
TMPRSS2
21q22.2-q22.3
Breakapart
–
25 or 50
LPS 098-A
TOP2A
17q21.2
Amplification/Deletion
D17Z1
50 or 100
LPS 002-A
ZNF217
20q13.2
Amplification
20pter
50 or 100
LPS 005-A
Cat. No. LPS 020-SA Cat. No. LPS 020-A
2p21
C2orf91 SHGC-106023
PKDCC
EML4 RH120737
KCNG3
MTA3
D2S2306
* for smaller volume probes add -SA to catalog number, e.g: LPS ###-SA RH94235
406kb
353kb 100kb
Cytocell Ltd, 3-4 Technopark, Newmarket Road, Cambridge, CB5 8PB T: +44 (0) 1223 294048 F: +44 (0) 1223 294986
Oxford Gene Technology Inc. 520 White Plains Road, Suite 500, Tarrytown, NY 10591, USA T: 860.298.8382 F: 860.298.8586
E: probes@cytocell.com
E: probes@rainbowscientific.com
www.cytocell.com www.myprobes.com
www.ogt.com US-BPATH15-V001/2015_03
Pathology Probes for 2015
Cat. No. LPS 019-SA
(100μl)
ALK Breakapart Probe Specification
(25μl)
Cat. No. LPS 509-SA
(25μl)
Cat. No. LPS 511-A
(50μl)
Cat. No. LPS 509-A
(50μl)
ROS1-GOPC(FIG) Distal
(50μl)
Cat. No. LPS 019-A
Cat. No. LPS 511-SA
RET Distal
ROS1-GOPC(FIG) Distal, 6q22.1, Red
Probe Specification
The ROS1-GOPC(FIG) distal probe consists of a red probe (206kb) covering the distal part of the ROS1 gene and a region up to RH78348.
ALK, 2p23.2-p23.1, Red ALK, 2p23.2-p23.1, Green
The ALK Breakapart probe consists of a green 420kb probe, which spans the majority of the ALK gene and a red 486kb probe, which is telomeric to the ALK gene.
The RET Distal probe consists of two probes (351kb, 112kb), labeled in red, situated distal to the RET gene and covering markers D10S1176 and D10S2221.
6q22.1
10q11.21 RET
ROS1
2p23.2-p23.1 SPDYA FAM179A CLIP4 PPP1CB WDR43
DCBLD1
D2S2312
FXYD4
ZNF487
HNRNPF
ZNF239
351kb
100kb
D10S2221
112kb
206kb
420kb
100kb
Cat. No. LPS 022-SA
(50μl)
Cat. No. LPS 022-A
(100μl)
ROS1 Breakapart
Cat. No. LPS 510-SA
(25μl)
Cat. No. LPS 508-SA
(25μl)
Cat. No. LPS 510-A
(50μl)
Cat. No. LPS 508-A
(50μl)
ROS1-GOPC(FIG) Proximal
RET Proximal
ROS1-GOPC(FIG) Proximal, 6q22.1, Green
Probe Specification
Probe Specification
The ROS1-GOPC(FIG) proximal probe consists of 3 probes (175kb, 123kb, 171kb), labeled in green, situated proximal to the ROS1 gene and including markers D6S2428 and SHGC-149552.
ROS1, 6q22.1, Red ROS1, 6q22.1, Green
The ROS1 Breakapart probe consists of a green 406kb probe and two red 299kb, 171kb probes, which are positioned on each side of the ROS1 gene.
RET Proximal, 10q11.21, Green
The RET Proximal probe consists of two probes (92kb, 303kb), labeled in green, situated proximal to the RET gene and covering markers G17488 and D10S1100.
6q22.1
10q11.21 6q22.1 FAM162B
FAM162B GPRC6A
ROS1
RFX6
D6S1873
D6S2428
D6S1072
DCBLD1 GOPC
KPNA5
NUS1
D6S1073
171kb
100kb
ROS1
RFX6
GPRC6A
D6S2428
DCBLD1
GOPC
LINC00839 CCNYL2
BMS1
ZNF33B
D10S1100
ZNF37BP
SHGC-149552
G17488
D6S1954
175kb 299kb
ZNF485
RH78348
D2S2383
100kb
Probe Specification
CSGALNACT2 RASGEF1A D10S1176
D2S2934 D2S405
486kb
GOPC
ALK RH104060
TRMT61B
RET Distal, 10q11.21, Red
Probe Specification
406kb
123kb
92kb
171kb 100kb
303kb
100kb
RET