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What this patent means This specific health technology is • recognized by a government agency, • novel and has not existed before, • unique and not available anywhere else, • protected and cannot be imitated.
What is the difference from a pharmaceutical drug patent
Target markets
Purpose of patents This information sheet provides health research established in con nection with natural disease pre vention. For patients, we rec ommend to see a therapist or trained consultant to determine your individual health needs.
www.drrathresearch.org
Consequences for your health Consequences for national economies
#1896/01EN/231122 Art. Nr.: 30007
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Over the ensuing decades, the Institute’s research team, under the leadership of Dr. Aleksandra Niedzwiecki, has extended this life saving research to comprise natu ral prevention of cancer, diabetes, viral and bacterial infections and Senior scientists of the Dr. Rath many other diseases. Research Institute with The approval of this preventive Dr. Niedzwiecki (center) health research by patent offices Dr. Rath Research Institute around the world provides the sci in San Jose, California entific basis for effective preven tive health strategies globally. Pa tients, therapists, governments and, above all, millions of people now have effective, safe, natural health approaches avilable to help to prevent widespread diseases.
Patented technology to help to optimize cellular sugar metabolism ENT OF AT
Dr. Matthias Rath
Micronutrients and Diabetes
T OFFIC EN
The Dr. Rath Research Institute is a world leader in sciencebased natural health. Three decades ago, Dr. Matthias Rath – together with twotime Nobel Laureate Dr. Linus Pauling (†1994) – was already pub lishing groundbreaking discoveries on the importance of vitamins in fighting cardiovascular diseases.
‘Science‐based natural health is the basis of modern, preventive health care.
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Nobel Prize‐winner‐supported research paves the way to preventive health care
Pharmaceutical investment business
Natural health community
Disease management
Disease prevention
Legal tools to secure return on investment (ROI) Cementing continua tion of diseases as global markets
Disease prevention and potential elimination
Exploding health care costs
Less diseases = lower health care costs
Scientific acknowledgement
Natural health research – the basis of preventive health
High blood sugar levels
Pharmaceutical composition Mix A to treat health conditions associated with elev ated glucose levels Inventors: Madhurima Chatterjee, Matthias Rath, Aleksandra Niedzwiecki, Anna Goc Publishing date: June 7, 2022
• Micronutrients increase glucose uptake by cells One of the important ways to nor malize elevated blood glucose levels is to optimize uptake of glu cose by the cells of our body. The adjacent graph (A) shows that a combination of three micronutrient compositions (core, mineral and D3/K2), taken together, could en hance cellular glucose uptake more than fivefold compared to a con trol. Better cellular glucose uptake means less glucose in blood. • Micronutrients increase insulin secretion by pancreatic cells
The pancreas and vascular system at the center of diabetic health problems. disease have been largely un known, and treatment has con sisted of lowering blood sugar levels with various drugs. However, diabetic cardiovascular complica tions occur even in those patients with controlled blood sugar levels. Thus, lowering blood sugar levels is a necessary but incomplete measure to address diabetic dis orders.
New research shows that the pri mary cause of adult diabetes is a longterm deficiency of dietary vi tamins and other essential nu trients in the cells of our body. This affects particularly the pancreas, the organ that produces insulin, and the blood vessel walls. Opti mum intake of micronutrients can help to prevent the onset of adult diabetes and its complications.
Insufficient insulin production by the hormonal cells of the pancreas is a primary cause of diabetes. The results on the adjacent graph (B) show that specific micronutrient combinations can increase the se cretion of insulin by pancreas cells in a natural way. At the highest mi cronutrient concentration tested in this study, the insulin secretion was twice as high as in controls. More insulin means more cellular glu cose uptake and, hence, a lowering of high blood sugar. • Micronutrients help to protect nerve cells from diabetic damage One of the longterm complications of diabetes is the deposition of dan gerous byproducts generated by high glucose. These socalled Ad vanced Glycation End Products
(AGEs*) include certain proteins, lipids and other compounds. By be coming encrusted with sugar mole cules, these AGEs can have a toxic effect on all cells, and in particular on the cells of the nervous system. Further results show that a triple combination of micronutrients can protect up to 80% of nerve (glial) cells from the deadly damages caused by AGEs. The more cells sur viving high glucose damage, the better the nervous system is pro tected in diabetes. Find further information and studies on diabetes on this website.
Vitamin C B vitamins Vitamin D3 Vitamin E Folate and biotin Larginine LLysine Calcium and choline Cinnamon extract Zinc and other micronutrients
A Micronutrient combinations increase cellular sugar uptake as a precondition for normalizing high blood sugar 45
Improvement Best efficacy
40
Sugar uptake in cells
US Patent No. US11351148B1
Scientists at the Dr. Rath Research Institute have developed a combi nation of micronutrients that has been proven to affect decisive cel lular mechanisms involved in dia betes.
The following experiments were part of the scientific proof that led to the Patent Office approval of this natural technology to help fight diabetes.
22-Deoxyglucose uptake (mM)
More than 60 million people in Europe suffer from diabetes, and hundreds of thousands die each year from complications of this disease. Diabetic disorders have a genetic background and are di vided into two types: juvenile dia betes (Type 1), and adultonset diabetes (Type 2). Juvenile dia betes requires regular insulin in jections from a young age. The ma jority of diabetic patients, however, develop this disease later in life. Until recently, the causes that trigger the sudden onset of the
Groundbreaking natural health research
Micronutrient combinations help normalize high blood sugar levels
more than fivefold
35 30 25 20 15 10 5 0
Control
Core Mineral D3/K2 Formulas: Combina�on D Combina�on Combina�on Core Combina�on D + Mineral + D3/K2
Figure A shows that different micronutrient combinations (blue) can greatly increase the uptake of sugar by body cells, and thereby help to lower elevated blood sugar levels. Taken together, these micro nutrient combinations can increase the sugar uptake more than five fold compared to controls.
B
Micronutrient combinations increase insulin secretion of human pancreas cells 250
Insulin (pikograms/ml)
Patented technology to help to normalize high blood sugar levels – naturally
Allowed patent claims: • A micronutrient composi tion used for treating dia betes ... by increasing cellular glucose uptake and increasing insulin production. • A micronutrient composi tion that protects a glial cell against damage by AGEs.*
Insulin production more than doubled
200
150
100
50
0
Control
19,7
39,4
78,8
Combina�on (μg/ml)
Figure B documents another breakthrough experiment from this pa tent. Micronutrient combinations can stimulate the production/secre tion of insulin — the decisive sugarlevelregulating hormone – in human pancreas cells. Thus, optimum micronutrient supplementation contributes to optimum availability of insulin in healthy people and to insulinsparing in diabetic patients.