Novartis by Shibu Lawrence

3 Steps to Improve Your Tablet’s Performance 1 – “Defrag” your hard drive

How to turn wireless Off:

During the normal course of usage, your files become fragmented and scattered across your hard drive. This results in decreased performance because it takes your computer longer to find the pieces and rebuild the file. When you defragment your hard drive, the files are organized so they can be accessed faster.

1. Press Fn+F5 on your keyboard.

Prior to defragmenting, delete old documents, such as reports, that are no longer pertinent or in use. When considering documents for possible deletion, be sure to review any Preservation Memos you may have previously received from the NPC Legal Department, and do not delete any documents that you are required to preserve for any legal matter.

3. The label on the button will change to Radio On.

Here’s how to defragment your hard drive: 1. Click Start > Utilities > Defragment Drive C. 2. The process will display an Analysis Report.

2. Check the Status — when the Status is On, click the Radio Off button.

4. The Status will now be Off and the radio tower color will be gray.

Tip: Turn wireless signal Off before you shutdown your tablet for a faster boot up during your next logon.

3. Defragmentation Complete message will display when done.

3 – Check your battery settings

Depending on the amount of defragmentation, the first time may take several hours, so it’s best to do this overnight.

The Novartis Optimized battery setting was developed to provide you with the best performance while using your tablet in the field. Using another battery setting will result in decreased performance.

Tip: To maintain good performance, defragment your hard disk on a monthly basis. When you establish a monthly routine, the process will be shorter.

2–Turn wireless off when not needed Leaving the wireless capability turned on when you’re not connected decreases performance, increases boot up time, and shortens battery life.

Here’s how to review your battery settings: 1. Click on the green battery icon in the lower right corner to open the Power Scheme menu. 2. Click on Novartis Optimized, listed first in the drop down menu. 3. Click outside of the Power Scheme menu to close or press the escape (ESC) key. Tip: Optimum battery performance is achieved when using the Novartis Optimized battery setting. Follow these 3 steps and your tablet will run faster.

Style Guide for Internal Communications

v.1 | June 2007

The Novartis Brand

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Contents

3 3

Overview

Contact

4 5 6 6 7 8 8 9 10 10 10 11 12 13 13 14 15

Internal Communications Overview Names and Descriptors Internal Logos Logo Elements Internal Logo Placement and Sizing Imagery Photography Illustrations Sample Layouts Print Poster, Banner, Podium sign Invitation, Tent card and Deskdrop Magazine and Newsletter Electronic PowerPoint E-newsletter and Intranet Multimedia Formats

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Overview

Welcome to the Novartis style guide for internal communications. For guidelines, templates, images and comments visit the Novartis Brand Service (NBS) website at: www.novartisbrandservice.com You can also contact the Novartis Brand Service team in Basel: Hotline +41 61 324 88 99 Fax +41 61 321 09 85 Email nbs@novartis.com

Internal communication materials aim to promote and educate Novartis associates on programs, events and tools within the company in order to help them achieve superior business results. With the reaffirmation of the Novartis brand, internal communication materials have also been updated. In order to keep the integrity of the Novartis brand, achieve better consistency, and reduce costs for the development and production of internal communication materials, new usage guidelines have been developed. This document offers guidelines for creating successful internal designs. However, there is no need to discard and replace existing materials. Before beginning a new internal communications design project, be sure to download and review the Core Principles & Elements, Print Media, Intranet, Internet, or PowerPoint style guides from the NBS website. These guides provide in-depth detail on the brand personality, core visual principles, and proper use of the corporate logo as they apply to print and electronic media, in addition to the design specifications pertinent to each media format.

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Internal Communications: Overview

Internal communications should follow the same design guidelines as external materials. Please visit the NBS website to download the style guide relevant to your project type to get in-depth design specifications.

Title

Masthead Subtitle | Business Unit

Contents Title

Contents Featured pg5

A Novartis logo (either the corporate or relevant BU/Institute version) must be present on all internal communications. If using an internal logo please follow the guidelines outlined in this document.

Internal Initiative Headline text can be placed here. For more info go to: http://www.webaddress.com

Cover Head – Lorem Ipsum Dolor Sit Amet Text Intro – Dolor sit amet, consectetuer adip itoing elit, diam non ummy nibh euismod tincidunt ut laoreet dolore sit ali. Text 1st ¶ – Disto odio digni pessim qui blandit praesent lup tatum azrildelenit augue duis dolor sit amet, consectetuer adipiscing elit, ut pat. Ut wisi enim nuad eu feugiat nulla facilisis sim quise blandit praesent. Usto odio sim. Text – Dolor sit amet, consectetuer adip itoing elit, sed diam nonummy nibh euismod sectetuer adip itoing elit, sed diam nonummy hendrerit in vulputate. Dolor sit amet, consec tetuer adip itoing elit, sedum diam nonummy nibh euismod hendrerit in vulputate. Text – Usto odio digni pessim qui blandit praesent lup tatum eros et accumsan et iusto odio dignissim qui blandit mod tincidunt ut sectetuer adip itoing elit, sed diam nonummy nibh euismod hendrerit in vulputate. Et iusto

sent lup tatum eros et accumsan et iusto odio dignissim qui blandit mod tincidunt ut laoreet facilisis at vero eros et qui modut accumsan et blandit praesent lup tatum azrildelen it augue duis dolore te feugait nulla facilisi sim qui. Adip iscing elit, sed diam nonummy nibh euis mod tincidunt ut laoreet dolore magna ali giat nulla facilisis at vero eros et qui modut accumsan. Text – Dolor sit amet, consectetuer adip itoing elit, sed diam nonummy nibh euismod hendrerit in vulputate. Dolor sit amet, consec tetuer adip itoing elit, sedum diam nonummy nibh euismod hendrerit in vulputate. blandit praesent lup tatum azrildelen it augue duis dolore te feugait nulla facilisi sim qui. Adip iscing elit, sed diam nonummy nibh euis mod sit > Story Continued To

Month Year | Issue

Internal Initiative Lorem ipsum dolor sit amet consectetuer! • Lorem ipsum dolor sit amet, consectetuer adipiscing. • Aliquam blandit posuere lectus.Sed vestibulum porttitor augue.Pellentesque suscipit blandit enim. • Maecenas ac magna ut erat imperdiet condimentum.Praesent venenatis aliquam arcu. For more info visit www.websiteaddress.com

Internal Initiative Headline text can be placed here. Fusce semper nisi non mi. Sed sodales purus vel massa. Nulla facilisi. Quisque pede velit, ultricies quis, ullamcorper a, tempor ut, diam. Integer egestas ante eget nulla. Etiam turpis nisi, dignissim eget, sollicitudin sed, iaculis a, lacus. Integer ante. Nullam a metus.

Concequat pallente nam commodo libero necing

Lorem ipsum dolor sit amet, consectetuer adipiscing elit.

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Internal Communications: Names and Descriptors

Internal initiatives can be quite effective without an internal logo. Internal communication materials use names and descriptors to identify the initiative or program they are a part of. Names and descriptors often appear as titles or headers in internal communication materials. The examples on the right show how to apply them in a layout. The Novartis logo must appear on all material covers.

Internal Initiative Name

Headline Text Lorem ipsum dolor sit amet dobem adipisicing elit, sed do eius mod.

Internal Initiative Name

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Internal Logos: Logo Elements

In order to create higher impact for corporate/BU/institute logos, achieve more consistency for the Novartis Brand, and minimize costs, internal logos should only be created for projects which are very important and have long-term usage. To justify owning a logo, there should be compelling communications, a strong need for recognition by target audiences and benefit to the Novartis reputation and/or business. - Top priority occasions, events & projects (e.g. Community Partnership Day) - Strategic initiatives (e.g. Getting to One, IQP) For tools and applications, please refer to the Guidelines for Application Branding available on the NBS website.

Color Usage Internal logos use the Novartis color family and white. Novartis Blue is used exclusively in the corporate logo, never elsewhere. Fonts All internal logos should use the Novartis fonts: News Gothic MT or Sabon. Please refer to the Core Elements Style Guide for specifics.

Internal logo with mark

Internal logo with symbol

A logo can simply use typography without any graphic elements. Graphic Elements Both marks and symbols are allowed as graphic elements of an internal logo. - Marks are graphics that are integrated into typography - Symbols are graphics that are independent of type but may be paired with it - Logos must not use any part of the corporate logo

Internal

LOGO

Internal logo with symbol

Typographic internal logo

Novartis blue is only for the Novartis corporate logo.

No part of the official Novartis logo should be used with internal logos.

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Internal Logos: Internal Logo Placement and Sizing

In all internal communications, the Novartis logo must accompany an internal logo if one is present. The Novartis logo must appear on all collateral covers and multimedia title frames. Placement in layouts - The Novartis corporate logo always sits on a band of white - Internal logos may sit: on a band of white and be visually aligned with the baseline of the corporate logo; on a color block; within a picture box - Do not replace the corporate logo with an internal logo. The Novartis corporate logo should always be used in collaboration with the internal logo if one is present - The corporate logo must always be aligned with the core vertical

Layout showing the internal logo within a picture box.

Internal Initiative Headline text can be placed here.

Size relation - The Novartis corporate logo must follow the grid calculator to determine size - There is no minimum or maximum size recommendation for the internal logo relative to the Novartis corporate logo. Internal logo size will depend on the specific needs of the layout

For more info go to: http://www.webaddress.com

Internal Initiative Headline text can be placed here. Lorem ipsum dolor sit amet, sectetur adipisicing sed dotempor incididunt ut sectetur adipisicing elit, sed do eiusmole. Adipisicing elit, dolore magna aliqua.

Layout showing the internal logo on a color block. While an internal logo may appear in various locations, the Novartis corporate logo always sits on white and follows the core vertical.

Internal Logo

Layout showing the internal logo sitting aligned with the Novartis corporate logoâ&#x20AC;&#x2122;s baseline.

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Imagery: Photography

The Novartis brand identity is expressed through its imagery. Images from the Novartis Corporate Image World can be used whenever applicable. For more information on the Image World see the Core Principles & Elements Style Guide on the NBS website. Internal communication materials are also allowed to use photos that show people, places and things relevant to the materialâ&#x20AC;&#x2122;s subject matter. Whenever possible use images with natural-looking lighting and an overall warm tone. Backgrounds that are blurred allow the people or objects in the foreground to be the main focus.

Employees

Events

Employee photos To make employee photos more dynamic, avoid overly posed subjects. The photo should be taken at eye-level against an unobtrusive background so the subject stands out. A more horizontal cropping is preferred. Event Photos Photos taken at conferences, awards presentations and trade shows should not feel overly staged. Candid photos of participants interacting are a refreshing alternative.

Building exterior/interiors

Building exterior/interior photos Building exteriors and interiors should show the environment from a natural perspective. Objects Objects should be shot in natural looking light. A simple background makes the object the focus of the image.

Objects 8

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Imagery: Illustrations

Illustrations are typically used to represent metaphors and ideas not easily captured by photography. They can also depict real subject matter in an informational way, such as in medical illustrations. Illustrations can be categorized into four main varieties based on the content or the subject matter they represent.

Informative

Metaphors

Metaphors show subject matter that is not based in reality but which is a composite of real or imagined situations that represent a larger concept or story. Informative illustrations represent objects and situations found in the real world in a stylized manner. Icons quickly identify an idea or situation in a simplified symbol. Icons

Graphic Logo Illustration

Graphic Logo Illustrations created from the internal logo itself can be used as an illustration graphic next to a color block. Illustrations should be warmly colored to compliment the Novartis color family. Medical illustrations, however, do not need to follow this rule. Never use any part of the corporate logo as an illustration. Do not use elements of the corporate logo in an illustration.

Illustrations should be warmly colored. 9

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Sample Layouts: Print: Poster, Banner, Podium Sign

Signage consists of posters, banners and podium signs. These are an opportunity for large areas of image and color. Because many poster sizes will be non-standard, be sure to use the grid calculator to determine all measurements.

Internal Initiative Name

Headline Title Goes Here Subhead text can be placed here.

Internal Initiative Headline text can be placed here.

Lorem ipsum dolor sit amet, sectetur adipisicing elit, sed dotempor incididunt ut sectetur adipisicing elit, sed do eiusmoles domus clover tium hfdsf hfdjsla et dolore magna aliqua.

Internal Initiative

Sectetur adicing elit, sed do eiusmod tempor incididunt.

Headline text can be placed here.

Lorem ipsum dolor sit amet, sectetur adipisicing elit, sed dotempor incididunt ut sectetur adipisicing elit, sed do eiusmoles domus clover tium hfdsf hfdjsla et dolore magna aliqua. Sectetur adicing elit, sed do eiusmod tempor incididunt. Adipisicing elit, dolore magna aliqua.

For more info go to: http://www.webaddress.com

Posters

Internal Initiative Name Lorem ipsum dolor sit amet. Ut wisi enim ad minim veniam, quis exerci tation ullamcorper suscipit lobortis nisl ut ex ea commodo. Go to www.urladdress.com

Banner

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Sample Layouts: Print: Invitation, Tent Card and Deskdrop

Invitations, tent cards and deskdrops use basic design that follows the core principles. As shown in these examples, there is flexibility within the parameters of the design guidelines.

Lorem ipsum consectetuer QUAM EU TORTOR VUL TRISTIQUE. • Vivamus posuere. • Mauris nonummy faucibus. • Ut quis nunc elementum.

Internal

LOGO

Deskdrops

Tent Card cover and interior Concequat pallente nam commodo libero necing

Invitation cover and interior 11 Internal Communications | Novartis Brand Style Guide | © Novartis 2007 | www.novartisbrandservice.com

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Sample Layouts: Print: Magazine and Newsletter

In materials such as magazines and newsletters, it is appropriate to use larger areas of color and image, or a more “editorial” design style.

Masthead

Internal Initiative NPC is mobilizing for launch. Read how seven associates are getting involved.

Also Inside

Internal Logo

Nancy Lurker Catching up with the chief marketing officer | 4

Nancy Lurker

A Day in the Life

Catching up with the chief marketing officer | 4

A field rep’s “day at the office” | 9

A Day in the Life A field rep’s “day at the office” | 9

The Magazine for NPC Associates December 2006 | Issue 3

Magazine covers

Month Year | Issue

Title

Masthead Subtitle | Business Unit

Contents Title

Contents Featured pg5

Internal Initiative Name

Contents Title

Text Intro – Dolor sit amet, consectetuer adip itoing elit, diam non ummy nibh euismod tincidunt ut laoreet dolore sit ali. Text 1st ¶ – Disto odio digni pessim qui blandit praesent lup tatum azrildelenit augue duis dolor sit amet, consectetuer adipiscing elit, ut pat. Ut wisi enim nuad eu feugiat nulla facilisis sim quise blandit praesent. Usto odio sim. Text – Dolor sit amet, consectetuer adip itoing elit, sed diam nonummy nibh euismod sectetuer adip itoing elit, sed diam nonummy hendrerit in vulputate. Dolor sit amet, consec tetuer adip itoing elit, sedum diam nonummy nibh euismod hendrerit in vulputate. Text – Usto odio digni pessim qui blandit praesent lup tatum eros et accumsan et iusto odio dignissim qui blandit mod tincidunt ut sectetuer adip itoing elit, sed diam nonummy nibh euismod hendrerit in vulputate. Et iusto

Masthead Subtitle | Business Unit

Contents Featured pg5

Month Year | Issue

Newsletter covers

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Sample Layouts: Electronic: PowerPoint

PowerPoint presentations follow the same general design guidelines as other formats, with adjustments made for type legibility and brightness of color when projected. To keep slide decks consistent, the Novartis logo should remain the same size as it is in the corporate PowerPoint template. As with other materials, if using an internal logo in a PowerPoint presentation it may sit on white, a color block or within a picture box. Internal logos may appear on all slides. For further design specifications download the PowerPoint Style Guide and User Guide from the NBS website.

Initiative title slide without image

Initiative title slide with image

INTERNAL LOGO

Logo title slide

Logo agenda slide

Text slide

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Sample Layouts: Electronic: E-newsletter and Intranet

While electronic media are used in fundamentally different ways than print media, the design of Novartis internet and intranet web sites, as well as e-newsletters, is also guided by our core principles. Please note that internal logos may only appear on intranet, not internet, pages. For further specifications please visit www.novartisbrandservice.com and download the Novartis Intranet style guide, Novartis Internet style guide or examples of electronic newsletters.

E-newsletter

Intranet

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Sample Layouts: Electronic: Multimedia Formats

Internal videos and multimedia formats act much as posters, using larger areas of color and graphics. *Guidelines for internal videos and other multimedia formats will be developed by Q4 2007. Until then, please apply the Novartis design principles. For design suggestions, refer to the Posters section. Internal video

Internal video

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Giveaways and Merchandise Hints and Tips

v.1 | July 2007

The Novartis Brand

Giveaways and Merchandise Hints and Tips | Novartis Brand | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Contents

3 3

Introduction

Contact

Giveaways and Merchandise Overview

Logo Treatment Do’s and Don’ts Corporate logo plus product logo

Applying the Core Brand Elements

5 5

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Introduction

Welcome to the Novartis Giveaways and Merchandise Hints and Tips For guidelines, templates, images and comments visit the Novartis Brand Service (NBS) website at: www.novartisbrandservice.com You can also contact the Novartis Brand Service team in Basel: Hotline +41 61 324 88 99 Fax +41 61 321 09 85 Email nbs@novartis.com

With the reaffirmation of the Novartis brand, giveaways and merchandise have also been updated. Novartis branded giveaways and merchandise are an opportunity to promote and foster the Brand’s core values. By taking into account quality, necessity and appropriateness, giveaways and merchandise can be meaningful and lasting symbols of the Novartis Brand. It is important to familiarize yourself with the international policies of the companies you do business with. Be aware of cultural sensitivities when selecting giveaway and merchandise items. This document offers hints and tips for creating successful giveaways and merchandise for Level 1 and Level 2 in the corporate brand architecture. Before creating merchandise or giveaways, be sure to download and review the Core Principles & Elements and Internal Communications style guides from the NBS website. These guides provide in-depth details on the core brand elements including color and typography. Novartis has specific policies on gift giving. Please visit the Corporate Integrity & Compliance Intranet site at www.novartis.intra/corporate_ethics/policies.shtml to download Document #3, Corporate Citizenship Guideline: “Business Ethics – Bribes, Gifts and Entertainment.” Additionally, you must comply with your specific local regulations, legal requirements and other relevant policies and practices.

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Giveaways & Merchandise: Overview

When creating giveaways and merchandise start by identifying your audience and objectives. Is the item intended to: - Further a business relationship? - Express gratitude?

There are many opportunities and reasons for creating Novartis branded giveaways and merchandise. These include tradeshows, Novartis sponsored events and internal initiatives, among others. Giveaways and merchandise are intended to help support the Novartis Brand and promote initiatives and events.

- Reciprocate a gesture? - Promote company initiatives or events?

Consider what items would be most appreciated by the intended audience. Because giveaways and merchandise represent Novartis, quality and appropriateness are important. An item that is low-quality and/or useless is likely to be discarded. Such items not only reflect poorly on Novartis but add to environmental waste. Giveaways and merchandise are successful when they are functional and well-made. Color should also be considered when selecting merchandise for your international audience. Color has positive or negative associations which vary from region to region. Use Novartis colors whenever possible, otherwise choose warm neutral colors which complement the Novartis palette.

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Logo Treatment: Do’s and Don’ts

Appropriate use of the logo is the most important part of maintaining the Novartis Brand. The consistency of its appearance is critical to communicating the principles and overall strength of the brand. The following tips apply to both corporate logos (with and without the “caring and curing” tagline), and all BU and institute logos. Sizing The use of Novartis and internal logos on giveaways and merchandise should be elegant and discreet. A large logo dominating the item is distracting and overbearing and the item will most likely not be used.

Third-party logos If the Novartis logo is among other sponsor logos, all should be equally sized and subtle. Please note that the use of the Novartis name and/or logo for third-party commercial, advertising or reference purposes is not allowed. Internal logos There is no minimum or maximum size recommendation for an internal logo relative to the Novartis corporate logo. Please refer to the Internal Communications style guide for details.

Tote bag with correct thirdparty logo sizing

Tote bag with incorrect thirdparty logo sizing

T-shirt with discreet logo size and placement

T-shirt with oversized logo

If using an internal logo, please review the Internal Communications Style Guide for correct usage. Placement Logo placement also contributes to an item’s appeal. Consider placing the logo on an unexpected part of the item. Color Though the corporate logo is best represented in color on a white background budgetary constraints may only allow for one-color printing. In such cases, the corporate logo must be either white or black. If the material permits, an embossed or etched logo may also be used.

Umbrella with Umbrella with oversized logo discreet logo size and placement

Rollerball pen with color ‘caring and curing’ logo

Rollerball pen with etched logo

Rollerball pen with color logo on color 5

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Logo Treatment: Corporate logo plus product logos

Giveaway and merchandise items may also feature product logos in conjuntion with a corporate, BU or institute logo. - There is no minimum or maximum size recommendation for a product logo relative to the Novartis corporate logo. However, all logos should be elegant and discreet. - When using multiple product logos keep the logos equally sized so no product logo is visually dominant.

Front of T-shirt with BU logo and product logos

Front of T-shirt with BU logo

Back of T-shirt with multiple product logos

Tote bag with multiple product logos and corporate logo

Tote bag with multiple product names and corporate logo

- Multiple product names may also be listed in lieu of using product logos Please contact your legal department for guidance regarding the use of product logos in combination with the Novartis corporate logo with tagline “caring and curing.” Brand and logo guidelines exist for all of our products. Refer to these guidelines for proper product logo application.

Tote bag with product and corporate logo

Tote bag with multiple product logos and corporate logo

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Applying the Core Brand Elements

In additon to corporate and internal logos, giveaways and merchandise can also use the image & color block unit. Keep in mind not every giveaway or merchandise item is suited for this treatment. The item must be white and should have enough clear space to properly display the image & color block unit. The Novartis logo must appear with this treatment. Please download the Global or US grid calculator from the NBS website to determine the proper element sizes relative to the itemâ&#x20AC;&#x2122;s size.

USB flash drive

T-shirt

Mug

Tote bag

Wrong sized elements

No logo present

Background not white

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Core Principles & Elements Style Guide

v.5 | July 2007

The Novartis Brand

Begin >

Contents

3 4 5 6 7 8 9

Introduction: Core Principles

Contact

Overview: Brand Personality Brand Focus Brand Essence Core Brand Themes Brand Style

Logo Revised Tagline Placing the Revised Logo Minimum Space Requirement Business Unit and Institute Application Acceptable Unacceptable

Color Family

Typography Print & Electronic

11 12 13 14 15 15

18 19 19 20 21 22 23 24 24 25 26 27 28

The Grid

Layout Samples Print Brochure Publications Advertising Stationery Folder & Invitation

30 30 31 32 33 34 35 35 36 37

Electronic Microsoft Office PowerPoint Microsoft Office Word and Excel Internet & Intranet

Core Principles Primary White Core Vertical Color/Image Balance Image World Content Style Color Light Perspective Image Cropping Focus

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Introduction: Core Principles

Welcome to the Novartis brand style guide.

As we continue to expand our business and enhance our performance in the global market, we have reaffirmed the Novartis Brand. Understanding the Novartis Brand and how to properly communicate it is key to our success. This series of style guides will assist in the communication of the Novartis brand personality. On the following pages is a full overview of the brand personality: Brand Focus, Brand Essence, Core Brand Themes, and Brand Style. These concepts are the foundation for our Core Visual Principles. The strength of the visual Novartis brand identity revolves around the understanding and application of these three components: Primary White Core Vertical Color/Image Balance These principles are discussed and illustrated in the Novartis Brand style guides. Transition Phase: In March 2006, Novartis will begin to apply the new design to Novartis communications. There will be a transition period where communications may exist simultaneously in the old and new design. By the end of 2006 and continuing in 2007, the majority of Novartis materials will appear in the new design. You should use the new design for newly created materials, but there is no need to discard existing materials. There are no new guidelines for product-related materials in 2006.

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Contact/Service Support & Hotline

For guidelines, templates, images and comments visit the Novartis Brand Service (NBS) website at: www.novartisbrandservice.com. You can also contact the Novartis Brand Service team in Basel: Hotline +41 61 324 88 99 Fax +41 61 321 09 85 Email nbs@novartis.com

Novartis Corporate Brand Management — The Team (Back row) Thomas Nie; (middle row, left to right) Jenny Borgemehn, Chantal Grüter, Karin Erbacher, Tina Martens, Nadine Enke; (front row, left to right) Caroline Fabian, Christine Furler, Andrea Fedriga-Hägeli, Markus Renner, Felix Raeber.

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Overview: Brand Personality

The Novartis brand personality is the basis for the Novartis Brand, defining its content as well as the direction of its visual, written and verbal communication. The diagram on the right depicts the personality, and is described in detail on the following pages.

Leader and Driver

caring

Global Citizen

tic the pa m

Innovative

insp iri ng

Responsible

Patient

c u ri n g fact-b ase d

Performance-Driven Spirit and Organization

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Overview: Brand Personality: Brand Focus

Brand Focus The Novartis brand focus is the center of our brand. The Patient Patients are at the center of our work; they are the reason for what we do.

Leader and Driver

caring

Global Citizen

tic the pa m

Innovative

insp iri ng

Responsible

Patient

c u ri n g fact-b ase d

Performance-Driven Spirit and Organization

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Overview: Brand Personality: Brand Essence

Brand Essence The Novartis brand essence is comprised of the actions we perform to serve our brand focus. Caring We care about and feel empathy for patients and are committed to answering unmet health needs around the globe.

Leader and Driver

insp iri ng

Innovative

caring

Global Citizen

tic the pa m

Curing We provide medicines that make a difference; we cure diseases, ease suffering and improve quality of life.

Responsible

Patient

c u ri n g fact-b ase d

Performance-Driven Spirit and Organization

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Overview: Brand Personality: Core Brand Themes

Core Brand Themes Our core brand themes support, strengthen and enable the Novartis brand essence. They direct the broader content for all Novartis communication.

Innovative

Responsible Innovative Leader and Driver

caring

Global Citizen

tic the pa m

We seek to constantly innovate in the way we discover and develop successful new medicines, in the way we market and deliver those medicines to the patients that need them, and in the way we drive new standards for the industry.

insp iri ng

Leader & Driver

Patient

Responsible Global Citizen We operate in an ethical manner, offer transparency, abide by regulatory and legal requirements, and deliver quality products. We also choose to help patients and communities through our corporate social responsibility initiatives.

c u ri n g fact-b ase d

Performance-Driven

Performance-Driven Spirit and Organization

Spirit & Organization Financial success ensures our ability to care and to cure. Delivering sustainable positive return and value fuels our innovation, increases our ability to help patients, and allows us to adequately reward our employees and shareholders. Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Overview: Brand Personality: Brand Style

Brand Style The Novartis brand style characterizes our behavior and guides the tonality of all company communication.

Fact-Based We communicate with facts. We do not make boastful claims or unrealistic promises. Our transparency with patients and customers builds credibility and respect.

Innovative Leader and Driver

insp iri ng

Empathetic We identify and connect with the feelings and thoughts of our patients and stakeholders. We seek to understand and respond to their needs, and give them the respect they deserve, whoever they are and wherever they are present.

Responsible

caring

Global Citizen

tic the pa m

Inspiring We think whatâ&#x20AC;&#x2122;s possible. We strive to be best-in-class and drive for superior results. We challenge conventional thinking. We constantly seek the next breakthrough and provide new hope for patients.

Patient

c u ri n g fact-b ase d

Performance-Driven Spirit and Organization

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Logo: Revised

The Novartis logo has been revised, through adjustments to the letterspacing, to achieve greater presence and impact. In addition, the color blue has been made warmer to complement the Novartis color family. The logo is the foundation for all design within the brand. The revised logo should be used in all new applications, but it is not necessary to reprint materials that use the existing logo. Observe the minimum size requirement at right. See the Novartis Brand Services (NBS) website to access logos in all color and file formats: PMS for coated stock; PMS for uncoated stock; CMYK for 4-color process printing; JPG in RGB for Word, PowerPoint, video and web; JPG in CMYK for higher resolution requests; and PDF for viewing only.

20 mm

Minimum Acceptable Usage The minimum size of the logo is 20 mm or .8".

Never alter the logo in any way; the electronic logo files available on the Brand Service website are the only files that should be used.

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Logo: Tagline

Usage: -‘Caring and curing’ should only be used in conjunction with corporate efforts and when regulatory concerns are not raised. If products, product brands, or diseases are referenced, then the tagline may not be used. If the communication is related to Novartis corporate efforts (e.g. Purpose, Aspiration and Strategy booklets), and products, product brands, or diseases are not referenced, then the tagline may be used optionally.

Acceptable and Unacceptable for additional information regarding appropriate use of the logo. - The tagline can ONLY be used with the logo, never independently. - Country-specific language translations are currently being reviewed. For further information, please contact nbs@novartis.com

- At the corporate and country levels, the tagline may be used in internal and external communications. In product communications, however, the tagline may not be used. -‘Caring and curing’ is the only tagline used with the Novartis logo.

Alignment The logo & tagline should align using the ‘g’ descenders, not the baseline.

Observe the minimum size requirement at right. Never alter the logo in any way; the electronic logo files available on the Brand Service website are the only files that should be used. Trademark Rules: - The Novartis logo—its design elements, colors, and tagline—are trademarked. It cannot be altered in any way. See Application:

35 mm

Minimum Acceptable Usage The minimum size of the logo with tagline is 35 mm or 1.4".

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Logo: Placing the Revised Logo

When updating existing materials with the revised logo, match the width of the symbols of the two logos to achieve correct scale (see illustration at right). The revised logo should be used in all new applications, but it is not necessary to reprint materials that use the existing logo.

Width of logo symbol is measure of correct scale

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Logo: Minimum Space Requirement

Unless otherwise prescribed, the logo should be surrounded by an area of white space equal to at least two X-height units (see illustrations at right). The X-height is defined as a square whose sides are the same length as the height of the “NOVARTIS” letters in the brand logo.

x x

X-height

x x

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Logo: Business Unit and Institute Logos

Each Novartis business unit and institute should use the logo that has been created for it. These logos, like the corporate logo, have been revised. All rules regarding usage of the standard logo apply to the business unit and institute logos as well. Never alter the logo in any way; the electronic logo files available on the Brand Service website are the only files that should be used. Taglines cannot be used with business unit logos. See the NBS website to access logos in all color and file formats. Only Novartis business units and institutes are allowed to have their own logo. There are no separate logos for franchises, divisions or offices; instead, these entities should use the Novartis logo. See brand architecture on the NBS website.

40 mm

Minimum Acceptable Usage The minimum size of a business unit/institute logo is 40 mm or 1.6". If your format requires a smaller size, use the corporate logo instead of the BU or institute logo.

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Logo: Application: Acceptable

Appropriate use of the logo is the most important part of maintaining the Novartis Brand. The consistency of its appearance is critical to communicating the principles and overall strength of the brand. Never alter the logo in any way; the electronic logo files available on the NBS website are the only files that should be used.

Color logo on white

Color logo with tagline on white

Black logo on white

Black logo with tagline on white

White logo; use only when it is impossible to use either the full-color or black logo (e.g. on merchandise).

White logo with tagline; use only when it is impossible to use either the full-color or black logo (e.g. on merchandise.)

In all applications, the Novartis logo must appear on a white background. See Minimum Space Requirement and Primary White for additional guidelines. If the application is black and white, use the black version of the logo, maintaining the band of white. In third-party environments, e.g. when Novartis acts as a sponsor, the color logo on white should be used. If this is impossible, e.g. the background is a color, either the black or white logo should be used. Please note that the use of the Novartis name and/or logo for commercial, advertising or reference purposes is not allowed.

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Logo: Application: Unacceptable

A few examples of unacceptable logo uses. Never alter the logo in any way; the electronic logo files available on the NBS website are the only files that should be used. Do not change the colors of the logo.

Do not crop the logo.

Do not use elements of the logo individually or as a super graphic.

N O VA R T I S Do not alter the elements of the logo.

Do not change the logo typeface.

Do not use the color logo on a colored background.

Do not rotate the logo.

Do not skew or stretch the logo.

Do not use the logo on photographic backgrounds.

Think what's possible.

Do not add effects or shadows to the logo.

Do not use any other taglines with the logo.

Do not use the black & white logo in color applications.

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Color Family

The Novartis color family consists of white, the three logo colors, and five additional colors. Novartis Blue is used exclusively in the logo itself, never elsewhere. White is a key element in illustrating the Novartis visual identity. See Primary White.

Blue

Brown

Maroon

Logo color

Red

Orange

Logo color

Dark Yellow

Bright Yellow

Beige

Logo color

Pantone Coated

314C

4975C

492C

179C

152C

124C

116C

155C

Pantone Uncoated

314U

504U

704U

Warm Red U

144U

129U

108U

155U

Process Coated

100c 0m 10y 35k

70c 80m 100y 30k 30c 90m 100y 15k 0c 80m 100y 0k

0c 60m 100y 0k

0c 35m 100y 0k

0c 15m 100y 0k

0c 10m 25y 0k

Process Uncoated

100c 0m 10y 35k

60c 80m 100y 30k 10c 100m 80y 15k 0c 80m 100y 0k

0c 35m 100y 0k

0c 25m 85y 0k

0c 6m 100y 0k

0c 6m 18y 0k

0r 127g 161b

99r 67g 41b

146r 50g 34b

228r 76g 22b

236r 128g 38b

252r 175g 23b

254r 211g 0b

245r 235g 215b

007FA1

634329

923222

E44C16

EC8026

FCAF17

FED300

F5EBD7

RAL Classic

5019

8017

3011

2002

2011

1003

1023

9001

RAL Design

2105045

0402019

0303040

0405070

0606080

0757080

0808090

0759020

RGB HTML

Reserve blue for logo use only.

Tints in increments of 10% are an acceptable application of color. 17 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Typography: Print & Electronic

Appropriate typography is important in the presentation of the Novartis Brand. Guidelines at right explain which typefaces can be used in specific contexts; do not vary from these specifications or introduce other typefaces. Print Media News Gothic MT is the preferred typeface for all printed materials. Sabon, Novartisâ&#x20AC;&#x2122; second typeface for print applications, is used mainly for captions and call-outs. Electronic Media Arial is the preferred typeface for Email, PowerPoint, Excel and Word documents.

Electronic

News Gothic MT

Sabon

Verdana

Arial

ABCDEabcde12345 ABCDEabcde12345 ABCDEabcde12345 ABCDEabcde12345

For use in:

Headlines Subheads Body text Captions Chart text Call-outs Folios URLs

Captions Call-outs

Internet Intranet

Email PowerPoint Word Excel Usage guidelines for fonts in these contexts are in development, to be available in 2007. Until then, use the fonts that currently exist in company templates.

News Gothic MT is the preferred typeface for all printed materials.

Verdana is the preferred typeface for HTML text in internet and intranet webpages. For more information on proper typography, including issues of size, style, spacing, etc., refer to the style guide that is specific to your need: Print Media, Intranet, Internet, or PowerPoint. A note on font versions: You may have versions of both News Gothic MT and Sabon that are more recent (i.e., Adobe Open Type Sabon and/or Monotype News Gothic MT) than those that are available for download on the NBS website. These newer versions are the same as previous versions, and therefore safe to use. 18 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Core Principles: Primary White

The Logo

Paper Quality

The Novartis logo must always be positioned within an area of inviolable white space. This band of white is flexible, but always edge-to-edge. The band of white serves to create presence for the logo. It is different from and in addition to the Minimum Space Requirement. In General

Because brand materials will be primarily white, take extra care to ensure that paper used for printing has sufficient opacity. Paper quality is important and should not be sacrificed for budget purposes. This means that top quality paper should always be your first choice. For specific guides regarding American and European paper types, see Print Media Style Guide.

White brings elegance to the Novartis brand personality.

Electronic

White is the only proper setting for the Novartis color logo. White is the primary color of the Novartis brand personality窶馬ot red, orange, yellow or brown. These colors should be used for accent only. White is the optimal canvas for the Novartis color palette. White is the optimal canvas for the Novartis image world.

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Core Principles: Core Vertical

The primary visual emphasis of all Novartis publications should be strongly vertical, directing the viewer to the logo. The diagram and examples at right show how this core vertical is established by the Novartis logo. The top point of the vertical stroke of the “N” in the logo is aligned to the left edge of the image* (and thereby the right edge of the white rule). When designing large formats such as posters and billboards, the “text inset” of the text block becomes more apparent. Therefore, manual alignment of the text to the left edge of the image is necessary.

Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in hendrerit in vulputate velit esse molestie consequat,

Cover Title Cover Subtitle

See Print Media Style Guide for graphic element specifications. *Please note, for brochure interiors the grid is a mirror format. Therefore on right hand pages the color block lays to the right of the text box, meaning the text aligns with the right edge of the image.

Text Head – Nulla tristique ligula vitae lacus Nam varius auctor turpis sollicitudin. Text 1st ¶ – Nulla tristique ligula vitae lacus. Nam varius auctor turpis. Donec sollicitudin luctus massa. Nam massa libero, varius at, tincidunt in, pretium ut, ligula. Nam non enim. In eu quam. Nullam enim felis, auctor sed, pre tium a, suscipit molestie, lorem. Aliquam in ligula quis diam faucibus gravida. Curabitur

neque ante, iaculis non, imperdiet sed, tempor sit amet, justo. Vestibulum ali quet. Duis sodales felis eu quam. Vestibulum faucibus blandit neque. Nulla velit vestibulum sollicitudin thai osemper massa. Quisque libe. Donec sollicitudin luctus massa. Nam massa libero, varius at, tincidunt inenim.

www.novartis.com

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Core Principles: Color/Image Balance

Whenever possible, imagery should be used in the design of Novartis brand materials. Generally speaking, images from the Image World, i.e., Brand Personality images, should always be paired with color blocks unless the layout dictates otherwise (e.g. there may be too many other images/graphics and any additional would make it too busy or repetitive). Support images that are used in text, e.g. products, personnel, facilities, etc., should not be paired with color blocks. The image & color block unit should achieve a complementary balance: color is chosen to complement, not match, the image. The image should always be dominant—the color block simply provides accent. Note that the color blocks are always separated from the images by the white rule.

Vertical A4 brochure cover and interior spread Home is where the heart is. Ours beats in 140 countries .

Masthead BusinessUnit

See Print Media Style Guide for graphic element specifications.

Text Sidebar – Vel eum iriure dolor in hend rerit in vulpu tatem velit esse molestie consequat, vel illum dolore eu feugiat nulla ult facilisis at vero eros et accumula san et iusto duis dolore te feu gait nulla fisi. Nam liber.

Tagline – Dolore eu feugiat nulla

Text Intro – Dolor sit amet, consectetuer adip itoing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorp ter sus cipit lobortis nisl ut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in hendrerit in vulputate velit esse molestie consequat, vel illum dolore eu feu giat nulla facilisis at vero eros et accumsan. Text – Usto odio digni pessim qui blandit praesent lup tatum azrildelenit augue duis dolore te feugait nulla facilisi. Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo. Text – Autem vel eum iriure dolor in hend rerit in vulputate velit esse molestie consequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio dignis Text – Ribh ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl eut aliquip vex ea commodo consequat. Duis autem vel eum iriure dolor in hendrerit in vulputate velit esse molestie con sequat, vel illum tro dolore neu feugiat nulla dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio dignissim qui blandit praesent luptatum azrildelenit augue duis Text – Autem vel eum iriure dolor in hend rerit in vulputate velit esse molestie consequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio digni dolore te feugait. Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi

Newsletter

Magazine

Welcome home.

Issue # | Month Year

enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo consequat. Text – Ribh dictum ipsum. Fusce at est urna aliquet posuere. Nulla dignissim nulla et eros. Fusce quis metus. Ut sapien massa, tempus vel, cursus eu, commodo sed, velit. Nam volutpat tortor eget erat pretium ultrices. Donec a ante non ante ultrices euismod. Morbi vestibulum pharetra tellus. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Nam sapien. Proin suscipit convallis. Quisque velit. Etiam porta gravida arcu. Text – Ribh ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscip vit lobortis nisl tut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in hendrerit in vulputate velit esse molestie con sequat, vel illum dolore eu feugiat nulla facili siso at vero eros et acc tumsan et iusto odio dignissim oqui to blandit praesent luptatum azrildelenit augue duis dolore te feugait. Text Subhead – Ribh dictum ipsum delo Text 1st ¶ – Ribh ut wisi enim ad minim veni am, quis nostrud exerci tation ullamcom per suscipit lobortis nisl ut aliquip ex ea commo dol consequat. Duis autem velol eum iriure dolor rinty hendrerit in vulputate velit esse molestie con, vel illum doloren plu eu nullaat. Text – Ribh ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in hendrerit in vulputate velit esse molestie con sequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio dignissim qui blandit vulputate velit esse praesent luptatum azrildelenit augue duis dolore te augue feugait.

caring and curing

Poster

Style Guide 21

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Image World

The Novartis brand identity is primarily expressed through its imagery. Images bring ‘caring and curing’ to life. The “Image World” is more than a collection of images; it is an approach to imagery that reflects the Novartis brand identity. The stylistic parameters of the Image World reflect the brand style: inspiring, empathetic, and fact-based.

releases, which are necessary for the library. Please contact the Brand Service team to include your images. * According to industry standard, all images on the NBS website are posted as RGB jpgs in both high and low resolution. If your project requires CMYK images, open your downloaded RGB files in a photo editing program and make the conversion. Your files may then require color correction; use your discretion.

- The content of the images (people, situations, and actions) should feel real, meaningful, and engaging; - The style (color, cropping, focus, light, and perspective) should feel natural, warm & connected, and impactful. See the NBS website for a library of images.* When hiring outside photographers to create new imagery, art direction should follow the Novartis brand style parameters. This is also true for the selection of stock images. If a royalty free stock image is being purchased for a project, it might be a great addition to the Image World library. However, not all royalty free images have model 22 Core Principles & Elements | Novartis Brand Style Guide | © Novartis 2007 | www.novartisbrandservice.com

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Image World: Content

Image content refers to the subject, situation and/or action that the image is showing. Content in the Novartis image world reflects the brand style by showing people, places and situations that are inspiring (engaging), empathetic (meaningful), and fact-based (real). Content should not look contrived, posed, dull, exaggerated or fictional. This does not mean you cannot use models within a studio setting, but the resulting images must look real and authentic.

Not posed

No exaggerated expressions

No obvious models

No fictional subject matter

Not flat or dull

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Image World: Style: Color

The Novartis Color Family is warm. To complement this palette the images should also have a sense of warmth. Avoid images that feel cold (i.e., blue, green, or gray tones) or artificially colored. Warmth can be enhanced in an image by including warm-toned objects and backgrounds, or subjects that are wearing warm-toned clothing. You can also digitally add warmth to stock images that are slightly cool. However, the enhanced image should still look natural.

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Image World: Style: Light

Lighting in the Novartis Image World should look and feel natural. Subject matter should not be hidden in shadows or dramatically lit. This does not mean you cannot light your subject matter, but the lighting in the resulting image should look natural.

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Image World: Style: Perspective

The perspective of Novartis imagery is eye-level to elicit an authentic connection with the subject. Images shot from above or below should not be used.

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Image World: Style: Cropping

The crop of an image can increase visual interest and/or change the narrative of a picture. Images in the Novartis Image World are frequently cropped closely to the subject, in a strongly horizontal orientation. Original image

Cropped image

Original image

Cropped image

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Image World: Style: Focus

The focal point of an image shows what is important. Use a shallow depth of field to focus the viewerâ&#x20AC;&#x2122;s attention on your subject. If your image lacks a clear focal point, you can digitally blur (in a subtle manner) the area around your subject to define it. Make sure that the resulting image feels natural.

Original image

More defined focal point

Digital manipulation can alter depth of field 28 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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The Grid 2

Column

Gutter

The grid is the foundation of all print media applications. It has been designed with meticulous consideration for the core principles of the Novartis brand. 1

Margin The margin widths have been calculated to encourage maximum white space, i.e., Primary White, and to ensure compatibility with both printer and PDF use.

Column The division of the grid into four, eight or sixteen columns establishes the width of text boxes and art.

Row The division of the grid into four, eight or sixteen rows establishes the vertical starting position (hangline) for all text and graphics. The row gridlines determine the amount of white space above and below text columns.

Row

Gutter The gutter width has been determined specifically by and for the proportions of the News Gothic typeface.

Minimum Band of White x

1 Margin

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Samples: Print: Brochures

Brochure Covers These are an opportunity to use larger images and graphics than in other formats. Most brochure covers will feature an image plus its graphic elements: the color block and white rule. Their scale and placement within the grid are flexible. In any case, note that the logo should be given primary emphasis within a balance of white space and graphic elements, as shown here. Also note that the image is always dominant over its accompanying graphics.

Vertical A4 brochure cover and interior spread

Cover copy will always left-align to the “N” of the logo, and therefore to the white rule. Generally, title and subtitle copy will sit below the art, while descriptors (date, version number, location, etc.) may be placed above.

Intro Head – Maecenas Velit Mi Lacinia Vehicula

Suspendisse potenti. Nulla dapibus nisia ut augue. Proina a arcuvelous mi blandit dictum. Fusced eget nisi. Quisque condintum porttitor metus. Aenean quis nibhegf et purus mauris eleifend interdum. Fusce egestas sqe condimentum lacus. Suspendisse at eratea epurus, facilisis non, rhoncus.

Cover Title Cover Subtitle

Brochure Interiors The main visual principle of brochure interiors is white space. Offsetting this Primary White is a balance of images, graphic elements, and type styles.

Intro Text – Vivamus neque eros, vent tor enatis vitae, tristique nec, porttitor a tortor, arcu. Quisque egestas tortor ut erat. Curabitur neque. Donec pobo scelerisque aliquam mauris. Donec ul volutpat. Sed tortor nisi, sceleribe sqe vel, ullacorper at, vehicula eget, lacus.

Quisque egestas tortor ut erat. Curabitur neque. Donec scelerisque aliquam mauri risipsumeo. Quisque condimentum porti titorou metus. Aenean quis nibh et purus eleifend interdum nibh et purus. Proin tincidunt arcu in dolor erat. Maecenas dapibus erat quis lorem. Fuscead iaculis viverra erat purus. Maecenas ultricies nisi id turpis. Etiam ac velit. Quisque sagittis fau cibus mia dignissim dimsam. Text Subhead 1 – Lorem Ipsum Dolor Amet Text Subhead 2 w/Subhead 1 – Morbi Vehicula Euismod Text 1st ¶ – Od libero quis ipsum matis dapibus. Curabitur pretium velit et odio. Nam congue rutrum neque. Nunc sed magna. Aliquam justo. Etiam sed orci eu libero pharetra ultricies. Etiam a orci in leo lacinia blandit. Class aptent taciti sociosqu ad litora torquent per conubia nostra, per inceptoseous hymenaeos. Suspendisse sapien. Praesent pellentesque, tellus sit amet sagittis convallis, sem mauris feugiat nisi, ac faucibus nunc nisl vitae leo. Phasellus ullamcorper lacus non purus. Cras sit amet sapien posuere nisi luctus fermean etum. Integergrase orci sapien, tincidunt quis, varius vel, faucibus at, neque. Etiamasoy nequeg. Proin vitae felis id urna euismod lobortis.

Vestibulum tellus metus, scelerisque ut, varius sed, euismod non, mauris piscing eros. Maecenas sed lacusgh. Ut vitae enim. Vehicula, est risus solicitudin urna, vestibulum consectetuer velit nisl vel justo. Proin eleifend. Aliquam nonummy felis nec neque. Etiam consequat elementum turpis. Aenean id leo. Pellentesque id odio. Suspendisse malesuada. Nullam risus. Quisque scelerisque semper leo orbi. Text – In nunc dapibus dui id conse consectetuer. Aliquam pere llentesque, purus id varius consectetuer, arcu odio elementum est, in eleifend tellus diam non eroshilouf. Proin mauris nibh, lobortis a, posuere eget, vestibulum sit amet, libero. Aliquam lectus lor, dictum vel, pellentesque quis, blanditused porttitorous, lacus. Curabitureref pellentesque ultricies tortor. Aenean velit. Curabitur sit amet quam. Nulla facilisi. In varius, ante id cursus auctor, risus metus varius felis.

Folio Right – Cover Title | 9

8 | Folio Left – Cover Subtitle

Horizontal A4 brochure cover and interior spread

See Print Media Style Guide for complete specifications.

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Samples: Print: Publications

In publications such as magazines and newsletters, it is appropriate to use larger areas of color and image, or a more “editorial” design style. However the principle of Primary White must still be observed.

February 2006 | Premier Issue

Title The Magazine for Novartis Pharmaceuticals Corporation Associates

“We want to become the most admired and respected pharma company in North America” An exclusive interview with Alex Gorsky Also Inside

Getting in the Zone A Nationwide Campaign | 4

Careers of a Lifetime Celebrating Decades of Service | 8

Anatomical Travelogue Understanding Hypertension | 12

Magazine cover and interior spread Magazine cover

September 2006 | Issue 1 One | Novartis Vaccines and Diagnostics | pg 2

Title

Letter From…

Our global exchange | Novartis Vaccines and Diagnostics

Joerg Reinhardt, CEO, Novartis Vaccines and Diagnostics

Dear Associate, Text Intro large – Solor sit amet, consectetuer sit adipisc ling elit, sed diam nonummy nibh euismod tincidunt sit amet ut laoreet dolore magna aliquam erat volutpat magna. Text – Wisi enim ad eta mini veniam, quis nostrud exerci tation ullamcorp er suscipit lobortis nisl ut aliquip ex ea com consequat. Duis autem level eum iriure dolor in hendrerit in vulputate velit esse mo lestie consequat, vel illum dolore eu feu giat nulla facilisis at vero eros et accumsan Text – Pusto odio digni pessim qui blandit praesent lup tatum azrildelenit augue duis dolore te feugait nulla facilisi. Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo. Text – Autem vel eum iriure dolor in hend quat, vel illum dolore eu feugiat connulla vero

Inside look

Vel illum dolore pg5

Duis autem vel eum iriure dolor pg5

Story 1 – Lorem Ipsum Dolor Sit Amet Text Intro large – Dolor sit amet, consectetuer adip itoing elit, diam nonummy nibh euismod tincidunt ut laoreet dolore sit ali quam erat volutpat. Duis autem vel eum iriure. Text 1st ¶ – Disto odio digni pessim qui blandit praesent lup tatum azrildelenit augue duis dolor sit amet, consectetuer adipiscing elit, ut pat. Ut wisi enim ad eu feugiat nulla facilisis sim qui blandit praesent. Usto odio digni pes

sim qui blandit praesent lup tatum azrildelen it augue duis dolore te feugait nulla facilisi. Adipiscing elit, sed diam nonummy nibh euis mod tincidunt ut laoreet dolore magna ali giat nulla facilisis at vero eros et accumsan et > Continued on page 2

Sidebar Headline – Lorem Ipsum Dolor Sidebar Subhead Employee Name, Title; Dolor Sit Amet, Consectetuer; Nibh Elit, Sed Diam Nonummy; Dolor Sit Amet, Consectetuer

Sidebar Subhead Employee Name, Title; Dolor Sit Amet, Consectetuer; Nibh Elit, Sed Diam Nonummy; Dolor Sit Amet, Consectetuer

Story 2 – Lorem Ipsum Dolor Sit Amet Sidebar Subhead

Text 1st ¶ – Dolor sit amet, consectetuer adip itoing elit, sed diam nonummy nibh euismod hendrerit in vulputate. Dolor sit amet, consectetuer adip itoing elit, sed diam nonummy nibh euismod hendrerit in vulputate. Text – Usto odio digni pessim qui blandit praesent lup tatum eros et accumsan et iusto odio dignissim qui blandit mod tincidunt ut

sectetuer adip itoing elit, sed diam nonummy nibh euismod hendrerit in vulputate. Text – Usto odio digni pessim qui blandit praesent lup tatum eros et accumsan et iusto odio dignissim qui blandit mod tincidunt ut laoreet dolore magna. Text – Usto odio digni pessim qui blandit praesent lup tatum eros et accumsan et iusto

Employee Name, Title; Dolor Sit Amet, Consectetuer; Nibh Elit, Sed Diam Nonummy

Sidebar Subhead Employee Name, Title; Dolor Sit Amet, Consectetuer; Nibh Elit, Sed Diam Nonummy; Dolor Sit Amet, Consectetuer

> Continued on page 4

One | Novartis Vaccines and Diagnostics | pg 3

eros et accumsan et iusto odio dignis. Autem vel eum iriure dolor in hend rerit in vulputate velit esse molestie consequat, vel illum dolore eu feugiat nulla facilisis at vero quis nostrud exerci tation ullamcorper suscip eros et accumsan et iusto odio dignis. Text – Ribh ut wisi enim ad minim veniam, it lobortis sit nisl ut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in dolore eu feugiat nulla facilisis at vero eros et hendrerit in vulputate velit esse molestie con ulla dolore eu feugiat nulla at vero eros. Text – Te feugait. et accumsan et iusto odio dignissim qui blandit praesent luptatum azril delenit augue duis. Plubo autem vel eum iriure dolor in hend rerit in consequat, sit amet vel illum dolore eu feugiat vulpuillum dolore eum feugiat nulla facili sis at vero eros sit. Text – Ribh ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in dolore eu feugiat nulla facilisis at vero eros et hendrerit in vulputate velit esse molestie con ulla dolore eu feugiat nulla at vero eros. Te feugait. et accumsan et iusto odio dignissim qui blandit praesent luptatum azril.

People Profile 1 Text 1st ¶ – Dolor sit amet, consectetuer nibh elit, sed diam nonummy nibh. Lorem ipsum nonummy sed diam. Lorem ipsum dolor sit amet, a consectetuer adipiscing elit, sed diam nonummy nibh euismod tin cidunt nonummy sed diam. Usto odio adigni pessim qui blandit praesent lup tatuma u azrildelenit augue duis. Profile 2 Text 1st ¶ – Usto odio adigni pessim qui blanddolore telo feugait nulla facilisi. Usto odio adigni pessim qui blandit praesent lup tatuma u it praesent lup tatuma u azrildelenit augue duis. Tenim trad minim veniam, quis nostrud exerci tation talo ullamcorper suscipit lobortis nisl ut aliquip ex ea commodo. Usto odio adigni pessim qui blandit praesent lup tatuma u azrildelenit augue duis. Profile 3 Text 1st ¶– Autem vel eum iriure dolor in hend rerit in vulputate velito essen molestie conse quat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio dignis. Ribh ut wisi enim ad minim. Usto odio adigni

pessim qui blandit praesent lup tatuma u azrildelenit augue duis. Ut wisi enim trad minim veniam, quis nostrud exerci tation talo ullamcorper suscipit lobortis nisl ut aliquip sit ex ea commodo. Profile 4 Text 1st ¶ – Dolor sit amet, consectetuer nibh amet, consectetuer adipiscing elit, sed diam aliquam erat volutpat. Ut wisi enim trad minim veniam, quis nostrud exerci tation talo ullamcorper suscipit lobortis nisl ut aliquip sit ex ea commodo. Usto odio adigni pessim qui blandit praesent lup tatuma u azrildelenit augue duis. Ut wisi enim trad minim veniam, quis nostrud exerci tation talo ullamcorper suscipit lobortis nisl ut aliquip sit ex ea commodo. Profile 5 Text 1st ¶ – Usto odio adigni pessim qui blandit praesent lup tatuma u azrildelenit augue duis dolore telo feugait nulla facilisi. Usto odio adigni pessim qui blandit praesent lup tatuma u azrildelenit augue duis. Ut wisi enim trad minim veniam, quis nostrud exerci tation talo ullamcorper suscipit lobortis nisl ut aliquip.

Text Callout – Curabitur Mi Eu Justo Iaculis Viverra sit amet Curabitur Papo

Story 1 > Continued from page 1 consectetuer ela adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorp er suscipit lobortis nisl ut aliquip ex eatu commodo blusoi cosequat. in vulputate velit esse molestie consequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio dignissim qui blandit praesent lup tatum azril delenit augue duis dolore te feugait nulla facilisi. Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam non ummy te nibh beuismod Duis autem vel eum iriure dolor in hendrerit tincidunt ut laoreet lorem, dictum vel, pellentesque quis, blandit dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscip it lobortis nisl ut aliquip ex ea commodo consequat feugiat nulla facilisis at. Text Subhead – In nunc daibus dui id conse Text 1st ¶ – Consectetuer, arcu tell odio ele mentum est, in eleifend tellus diam non eros. Proin mauris nibh, lobortis a, posuere eget,

vestibulum sit amet, libero. Aliquam lectus lorem, dictum vel, pellentesque quis, blandit porttitor, lacus. Curabitur pellen diam tesque ultricies tortor. Aenean velit. Curabitur diam sit amet quam. Nulla facilisi. In varius, ante id cursus auctor, risus varius felis, posuere eget sit amet sodales. Text – Autem vel eum iriure dolor in hend rerit in vulputate velit esse molestie consequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio dignis. Text – Ribh ut wisi enim ad minim veniam, quis nostrud exerci tation ut wisi.

Headline – Lorem Ipsum Dolor Sit Amet Text 1st ¶ – Dolor sit amet, consecteuer adip cing elit, sed diam nonummy onibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorp er suscipit lobortis nisl ut aliquip ex ea commodo consequat tation ullamcorp. Text – Autem vel eum iriure dolor in hendrerit in vulputate illum velit esse molestie consequat, vel illum dolore eu

feugiat nulla facilisis at vero eros et accumsan et iusto odio dignissim vero qui blandit praesent lup tatum azrildelenit augue duis dolore te feugait nulla facilisi. Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam non ummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorper suscipit lobortis nislam ut aliquip ex ea commodo consequat.

Letters Text 1st ¶ – Solor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat magna. Text – Wisi enim ad eta mini veniam, quis nostrud exerci tation ullamcorp er suscipit lobortis nisl ut aliquip ex ea com consequat. Duis autem level eum iriure dolor in hendrerit in vulputate velit esse mo lestie consequat, vel illum dolore eu feu giat nulla facilisis at vero eros et accumsan. Pusto odio digni pessim qui blandit praesent lup tatum azrildelenit

augue duis dolore te feugait nulla facilisi. Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euis mod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullamcorp er suscipit lobortis nisl ut sit amet aliquip ex ea commodo. Text – Autem vel eum iriure dolor in hend rerit in vulputate velit esse molestie consequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odio.

Newsletter cover and interior pages

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Samples: Print: Advertising

Advertisements follow strict guidelines. They present a clear and simple expression of the Novartis brand to a wide audience. See the advertisement section of the Print Media Style Guide for specifications.

Novartis proudly supports the (organization) and its efforts to help (patients).

“Novartis helped me wipe out my cancer within months. Now I’m surfing the Pacific.”

Text 1st ¶ Left – Nulla lorem ipsum sit amet, con sectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullam corper suscipit lobotis nisl ut aliquip ex ea commodo consequat. Duis aut em vel eum iriure dolor in hendrerit in vulputate esse molestie lo consequat, vel illum dolore eu feul giat nulla facilisis at vero eros et accumsan et iusto odi nis qui blandit sent luptatum.

Surfing was a big part of Eran Thomson’s life until he was hit by a deadly cancer. It left him sick and beat up, but he never gave up. Then, a Novartis medicine drove his cancer into remission in a matter of months. No one can promise what the future holds for any cancer patient, but today Eran feels great. And now he’s living, working and surfing — on one of the best beaches in Australia. Think what’s possible.

www.us.novartis.com

www.novartis.com

Text Head – Nulla tristique ligula vitae lacus nam varius auctor turpis sollicitudin.

Novartis proudly supports the (organization) and its efforts to help (patients). Text 1st ¶ Left – Nulla lorem ipsum sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullam cor per suscipit lobotis nisl ut aliquip ex ea commodo consequat. Duis autem mel eum iriure dolor in hendrerit in vulputate velit esse molestie lo consequat, vel illum dolore eu feugiat nulla facilisis at vero eros et accumsan et iusto odi nis qui blandit sent luptatum zzril delenit augue duis dolore te feugait nulla facil Lorem ipsum dolor sit amet, consectetuer adipiscing elit, seda diam no ummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation.

www.novartis.com

Home is where the heart is. Ours beats in 140 countries .

www.novartis.com

Welcome home.

caring and curing

Text Head – Nulla tristique ligula vitae lacus nam varius auctor turpis sollicitudin. Text 1st ¶ Left – Nulla lorem ipsum sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat. Ut wisi enim ad minim veniam, quis nostrud exerci tation ullam corper suscipit lobotis nisl ut aliquip ex ea commodo consequat. Duis autem vel eum iriure dolor in hendrerit in vulputate velit esse.

www.novartis.com

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Samples: Print: Stationery

Novartis stationery templates can be downloaded from the NBS website. These templates contain precise placements and indications for type and the logo, as well as production indications for cropping and folding. Shown at right are a few samples of stationery formats; other formats are available online.

Label

Bernd C. Mustermann Media Desk Manager

Novartis International AG Corporate Communications CH-4002 Basel Switzerland Tel. +41 (0)61 324 79 13 Fax +41 (0)61 324 35 38 bernd.mustermann @novartis.com

Please note that there is no need to discard and replace existing stationery. However, apply correct guidelines when ordering new material.

Business card

The revised logo should be used in all new applications, but it is not necessary to reprint existing stationery materials.

US Letter A4 Letter

CH-4002 Basel Switzerland

C6 Envelope

C5 Envelope

33 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Samples: Print: Folder & Invitation

Folders and invitations use basic design that follows the core principles. As shown in these examples, there is flexibility within the parameters of the design guidelines.

Media Kit

Folder covers

NAME

LEADING IN INNOVATION — AND WINNING!

DEPARTMENT

I would like translation to: German English I need transportation from: Werk Stein Schweizerhalle/Muttenz

Lorem ipsum 2006 Consectetuer adipiscing elit. February 2, 2006 | Grosser Festsaal Messe Basel | 14.00 – 18.30 (including apéro) Meeting will begin promptly at 14.00

LANGUAGE The presentations will be held in English and German, with simultaneous audio translation in both languages. TRANSPORTATION Stein: Special shuttle bus departs from the gate at 12.55. Schweizerhalle/Muttenz: Shuttle bus departs from the main gate 2080 at 13.10 and from the front of building 2881 at 13.15. Return: Buses to Stein and Schweizerhalle/Muttenz will depart from Messe Basel at 18.45, following the apéro. St. Johann, Klybeck and Rosental: A special tram to Messe Basel (green, marked “E”, free of charge) will leave Hueningerstrasse at 13.10 and Voltaplatz at 13.15 (tram stop line 1, direction city). Peter Merian House: A special tram will depart from SBB at 13.20 (closest track to Peter Merian House, direction Aeschenplatz). ACCESS For security reasons, all associates must bring their Novartis ID. Those without appropriate identification will not be admitted to the event.

Invitation front and back

Lorem ipsum voultpat

Invitation front and inside February 2, 2006 | Grosser Festsaal Messe Basel 14.00 – 18.30 (including apéro) Meeting will begin promptly at 14.00

Quis risus. Duis volutpat. Donec et odio. Aliquam numrest tortor, suscipit eu, pulvinar non, scelerisque in. Fusce: Sodales lorem id felis. Pellentesque nunc nisi, faucibus condimentum et, molestie non, rutrum eget, risus.

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Samples: Electronic: Microsoft Office PowerPoint

PowerPoint presentations follow the same general design guidelines as other formats, with adjustments made for type legibility and brightness of color when projected. All PowerPoint style guides and tools are located on the NBS website. A PowerPoint software plug-in and template are also available for download for use by external agencies.

35 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Samples: Electronic: Microsoft Office Word and Excel

Microsoft Office Word and Excel templates have been updated. Electronic templates now solely use Arial. In both Word and Excel templates, a color picker tool has been added with the approved Novartis electronic colors. A manual on how to use the new Word templates is available on the NBS website.

Microsoft Office Word template

Microsoft Office Excel template displaying the color picker tool 36 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Samples: Electronic: Internet & Intranet

While electronic media are used in fundamentally different ways than print media, the design of Novartis internet and intranet web sites is also guided by our core principles. Style guides for both the Novartis intranet and internet are available on the NBS website, along with HTML templates, key graphic PSDs and an implementation guide.

Novartis Internet

Novartis Intranet

37 Core Principles & Elements | Novartis Brand Style Guide | ÂŠ Novartis 2007 | www.novartisbrandservice.com

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Sleep Impairment in Controlled and Uncontrolled Moderate to Severe Pediatric Asthma Bonnie B Dean, PhD1; Brian Calimlim, MS1; Daniel Aguilar, MPH1; Patricia Sacco, MPH, RPh2; Robert Maykut, MD2; and David Tinkelman, MD3. 1

Cerner LifeSciences, Beverly Hills, CA, USA; 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA; and 3National Jewish Medical and Research Center, Denver, CO, USA • Symptoms >2 days per week

BACKGROUND As a leading cause of hospitalization among children 3-12,1 asthma is associated with substantial direct medical costs.2

◆

There is also a burden associated with indirect costs of pediatric asthma with school days missed and impaired school performance.2 - 4

◆

34% of pediatric asthma patients experience nighttime symptoms5, and can experience impaired sleeping patterns, daytime sleepiness, and decreased mental performance.6

• Activity limitation due to impairment or health problem

OBJECTIVE ◆

To assess the association of uncontrolled moderate to severe asthma with nighttime sleep patterns and daytime sleepiness among children.

Child’s Sleep Interference ◆

Sleep Impairment

◆

Data Analysis

g Uncontrolled Asthma

65.8

Uncontrolled pediatric asthma is associated with significant sleep impairment that may result in morning or daytime sleepiness. Further research is needed to understand the impact of asthma-associated sleep impairment on development.

g Controlled Asthma

48.9

35.3

30 20

CITATIONS

25.7

14.2

13.3

15.0 10.6

6.2

0 Wakes up at night

Often or sometimes uses rescue inhaler at night

Often or sometimes has difficulty getting out of bed

Hard to wake in the morning at least once/week

Overly tired all day at least once/week

Note: all comparisons have a p-value<0.0001 except for difficulty getting out of bed (p=0.487)

– A random sample of adults from a general registry of internet users who had previously reported having at least one child received e-mail invitations to participate, followed by two e-mail reminders for non-respondents. ◆

Inclusion Criteria – >18 years of age and living in the US – Caregivers of children (aged 6-12 years) who:

◆

RESULTS ◆

– Of 16,396 invited to participate, 4,514 caregivers (27.5%) responded. – 473 caregivers satisfied the study criteria, completed the questionnaire, and were included in this analysis. • Mean age was 40.6 years

• Met criteria for “moderate to severe asthma” assigned using an algorithm based on current medications and healthcare utilization during the previous year

• 85.6% were Caucasian

Asthma Symptom Control – Symptom control was determined based on responses to key components of asthma control outlined in the NAEPP 2007 asthma guidelines7 – Children were classified as having uncontrolled asthma if their caregiver reported any of the following criteria:

– Compared with controlled asthma, children with uncontrolled asthma were significantly more likely to report waking up at night with symptoms, using a rescue inhaler at night, experiencing difficulty waking up in the morning, as well as being overly tired all day (p<0.0001). (Figure 1)

Study Sample

• Have a doctor’s diagnosis of asthma (caregiver-reported)

• 71.7% were married • 85.2% completed at least some college • Almost 40% from the south, 25% from the Midwest, and the remaining 35% evenly split between the western and northeastern U.S. – 360 were caregivers of children with uncontrolled asthma and 113 for children with controlled asthma.

Asthma symptom control criteria differed from NAEPP 2007 guidelines for rescue inhaler use, which may have underestimated severity in this study.

40.8

– Chi-square tests were used to assess differences in proportions for socio-demographics and sleep-impairment outcomes between children with uncontrolled versus controlled asthma.

– Cross-sectional internet-based survey conducted in July 2007.

◆

CONCLUSIONS

– Caregivers of children with uncontrolled versus controlled asthma were compared with respect to socio-demographic characteristics.

Study Design and Data Source

Inclusion was based on patterns of medication and utilization reported during the previous year. Classification of disease severity based on medications may be complicated by the assumption that prescribed treatment is appropriate to the severity level.

Figure 1. Measures of Sleep Impairment by Asthma Control

METHODS ◆

– Children with uncontrolled versus controlled asthma did not differ significantly in their gender, age, and race/ethnicity distributions.

– Children not meeting any of these criteria were classified as having controlled asthma.

– The SleepLearnPlay9 instrument and investigator- developed questions were used to assess the impact of nocturnal asthma symptoms on nighttime sleep patterns and daytime sleepiness.

◆

– Caregivers of children with uncontrolled versus controlled asthma did not differ significantly in their socio-demographics except that caregivers of children with uncontrolled asthma were more likely to be women (P = 0.019).

• Awakened by symptoms during the past 4 weeks, as measured by the Pediatric Asthma Symptom Score (PASS) instrument8

◆

Socio-demographics

Percent

◆

– 237 of 360 (65.8%) children with uncontrolled asthma were reported as experiencing nocturnal awakenings at least once per week, as compared to 16 of 113 (14.2%) children with controlled asthma.

LIMITATIONS ◆

The use of an Internet population may limit the ability to genneralize in this study.

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Recall and observer bias for symptom occurrence and severity among caregivers may have affected results.

1. Owens PL. AHRQ Publication No. 04-0004. 2003. 2. Asthma Prevalence, Health Care Use and Mortality, 2002. NCHS. 2002. 3. Environmental Hazards and Health Effects: Asthma's Impact on Children and Adolescents. DHHS, 2002. 4. Diette GB et al. Arch Pediatr Adolesc Med 2000; 154(9):923-928. 5. Children and Asthma in America: A Landmark Survey. Available at: http://www.asthmainamerica.com/children_index.html. 6. G Stores, A J Ellis, L Wiggs, C Crawford, A Thomson. Sleep and psychological disturbance in nocturnal asthma. Arch. Dis. Child. 1998;78;413-419 7. NHLBI. NAEPP Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. 2007. 8. Lara M, Sherbourne C, Duan N, Morales L, Gergen P, Brook RH. An English and Spanish Pediatric Asthma Symptom Scale. Med Care 2000; 38(3):342-350. 9. SleepLearnPlay. AAFA. Sponsored by Genetech, Inc. and Novartis Pharmaceuticals Corporation. http://www.sleepworkplay.com/questionnaire.php?quizChoice=child This study was funded by Genentech, Inc. and Novartis Pharmaceuticals Corporation. American Thoracic Society. (ATS) 2008 International Conference, Toronto, ON, Canada, May 16–21.

3 steps to improve your tablet’s performance 1 – “Defrag” your hard drive

How to turn wireless Off:

1. Press Fn+F5 on your keyboard.

3. The label on the button will change to Radio On.

Here’s how to defragment your hard drive: 1. Click Start > Utilities > Defragment Drive C. 2. The process will display an Analysis Report.

2. Check the Status — when the Status is On, click the Radio Off button.

4. The Status will now be Off and the radio tower color will be gray.

Tip: Turn wireless signal Off before you shutdown your tablet for a faster boot up during your next logon.

3. Defragmentation Complete message will display when done.

3 – Check your battery settings

Depending on the amount of defragmentation, the first time may take several hours, so it’s best to do this overnight.

The Novartis Optimized battery setting was developed to provide you with the best performance while using your tablet in the field. Using another battery setting will result in decreased performance.

Tip: To maintain good performance, defragment your hard disk on a monthly basis. When you establish a monthly routine, the process will be shorter.

2–Turn wireless off when not needed Leaving the wireless capability turned on when you’re not connected decreases performance, increases boot up time, and shortens battery life.