Toxicology of Mixtures 2011

Page 1

Chair Persons’ Welcome

Oral Program Day 1 - Friday 21 October 2011

Dear Fellow Colleagues, We are excited to announce what we hope will be a thought-provoking conference on the assessment of human risk associated with exposures to mixtures of toxic chemicals. Over the past several decades we have made substantial progress in refining methods for assessing risk for exposures to single chemical agents, yet we cannot ignore the fact that the majority of actual human exposures are to multiple chemicals; whether and how the individual chemical identities within complex and poorly defined chemical mixtures or combined exposures interact remains largely unknown. The subject of mixture toxicity has received growing interest and toxicologists have devoted increasing thought and resources to identifying the most appropriate and scientifically defensible means of assessing such risks. Yet we are only at the doorstep of understanding the underlying chemistry and biology and developing appropriate paradigms for dealing with these combined and interactive risks. The purpose of this international conference is to bring together thought leaders from throughout the world to discuss recent progress in defining mixture toxicology and to leverage an open forum for discussion to launch innovative approaches to better define approaches for assessing human risks associated with exposures to mixtures of toxic chemicals. Although we do not expect to reach a conclusive consensus, the goal of this meeting is to produce a critical cornerstone in advancing our understanding of mixture toxicology. We hope you are able to join in what we hope will be vibrant and paradigm-shifting discussions. See you in October,

21-23 October 2011, Sheraton National Hotel, Arlington, VA, USA

Conference Welcome Ken Wallace, University of Minnesota Medical School, USA

09.15-09.45

Historical Perspectives and Introduction on Chemical Mixture Toxicology Raymond Yang, Colorado State University and Ray Yang Consulting, LLC, USA

09.45-10.00

At Toxicology of Mixtures 2011 benefit from: • Reviewing the conventional models and methods but to also challenge established opinions and work towards the development of more precise modes for understanding the toxicity and predicting risk • Joining your international peers to effectively network with fellow Toxicologists, Risk Assessors and Regulators • Discussing, debating, and challenging the current research as well as networking with your colleagues

Kind regards,

Dr. Kendall B. Wallace, University of Minnesota Medical School

09.00-09.15

Dr. Jane Ellen Simmons, United States Environmental Protection Agency

For more information and to register now, go to:

www.toxicologyofmixtures.com

Current status, recent advances, remaining challenges Jane Ellen Simmons, United States Environmental Protection Agency, USA

10.00-10.45

Keynote 1: Novel Methods for Integrated Risk Assessment of Miracle Multiple Stressors Hans Løkke, Aarhus University, Denmark

10.45-11.15

Coffee Break

11.15-12.00

Keynote 2: Assessing Low-Level Mixtures When Chemical Specific Data are Lacking: Use of the Threshold of Toxicologic Concern Rosemary T. Zaleski, ExxonMobil Biomedical Sciences, Inc., USA

Day 2 - Saturday 22 October 2011 09.00-09.45

Keynote 6: Pesticides – Pesticide Mixtures (organophosphates, carbamates and pyrethroids) Anna Lowit, United States Environmental Protection Agency, USA

09.45-10.30

Keynote 7: What are mixtures of environmental relevance and how can they be assessed? Andreas Kortenkamp, University of London, UK

10.30-11.00

Coffee break

11.00-11.15

Short talk from abstract submissions

11.15-11.30

Short talk from abstract submissions

11.30 -12.15

Keynote 8: Pharmaceutical drugs and their impact on chemical toxicological risk assessment Sami Haddad, University of Montreal, Canada

12.15-13:45

Lunch

12.15-13:45

Poster Session 3

13.45-14.00

Short talk from abstract submissions

12.00-13.30

Lunch

14.00-14.15

Short talk from abstract submissions

12.00-13.30

Poster Session 1

14.15-15.00

13.30-14.15

Keynote 3: Highly-Complex Environmentally-Realistic Mixtures: Challenges and Advances Jane Ellen Simmons, United States Environmental Protection Agency, USA

Keynote 9: Toxicity and Assessment of Chemical Mixtures: Opinion of the scientific committees of Health & Consumer Protection DG of the European Commission Alan Boobis, Imperial College, UK

15.00-15.30

Coffee break

14:15-15.00

Keynote 4: Mixtures Research and the NIEHS and NTP: An Evolving Program Nigel Walker, National Institute of Environmental Health Sciences (NIEHS), USA

15.30-15.45

Short talk from abstract submissions

15.45-16.00

Short talk from abstract submissions

16.00 -16.45

Keynote 10: Ten Common Myths Associated With the Hazard Characterization of Chemical Mixtures Gerald LeBlanc, North Carolina State University, USA

16.45 – 17:45

Round Table Discussion Moderated by Ray Yang and Keynote Speakers 6-10

19.00

Conference dinner (Optional and Tickets can be purchased)

15.00-15.45

Round Table Discussion Moderated by Ray Yang and Keynote Speakers 1 - 4

15.45-16.15

Coffee break

16.15-16.30

Short talk from abstract submissions

16.30-17.15

Keynote 5: Evolution of the WHO IPCS Framework on Combined Exposures to Multiple Chemicals Bette Meek, University of Ottawa/Health Canada, Canada

17.15-18.30

Drinks reception

17.15-18.30

Poster Session 2

REMEMBER: Author Registration deadline is on 17th June 2011

Day 3 - Sunday 23 October 2011 09.00-09.45

Keynote 11: Risk from Multiple Chemicals in Polluted Communities Christopher J Portier, ATSDR, USA

09.45-11.30

Round Table Discussion – Current status and future needs Moderated by Ray Yang and Keynote Speaker 11

11.30-11.45

Closing remarks


21-23 October 2011, Sheraton National Hotel, Arlington, VA, USA

Registration for Toxicology of Mixtures 2011 is now open Academic/Government delegate

$750

Industry delegate

$900

Student delegate*

$590

Exhibition and Sponsorship Opportunities Interested in Sponsoring or Exhibiting? Toxicology of Mixtures 2011 will be a unique opportunity for companies to access international participants of the Toxicology, Risk Assessment and Regulation communities. For further information please contact Victoria Macomber at: Email: v.macomber@elsevier.com Tel: +1 508 3846170

21-23 October 2011, Sheraton National Hotel, Arlington, VA, USA

*The Student rate applies to those registered for a higher degree.

Registration fee includes: • Attendance to all conference sessions and poster/ exhibition areas • Program book and abstracts on CD • Mid-session refreshments • Lunch on Friday & Saturday • Welcome drinks reception

Contact Us For all types of queries, please contact us at: customerservicetoxicologyofmixtures11@elsevier.com

Join members of the international toxicology community in the discussion of current evidence based approaches to assessing the risk of mixtures.

For more information and to register now, go to:

For information on how to register visit:

www.toxicologyofmixtures.com

www.toxicologyofmixtures.com


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