105年會論文摘要集

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The

th Annual Meeting of March 19-20, 2016 The Endocrine Society and The Diabetes Association of the R.O.C. (Taiwan)

S2-1

Prof. Toshio Matsumoto, M.D. Personal Information Nationality: Japan Position: Director Department: Fujii Memorial Institute of Medical Sciences Organization: Tokushima University Email: toshio.matsumoto@tokushima-u.ac.jp Educational background & professional experience (in sequence of the latest year) 1974 University of Tokyo School of Medicine MD degree 1978-1981 Yale University School of Medicine Research Fellow Professor and Chair 1996-2014 Department of Medicine & Bioregulatory Sciences, Tokushima University Graduate School of Medical Sciences Research Interests 1 Regulatory mechanism of osteoblast differentiation and bone formation 2 Mechanism of development of cancer-associated bone disease 3 Roles of endocrine and other systems in the development of atherosclerosis Publications (5 important publications – latest sequence) 1. Dong B, Endo I, Ohnishi Y, Kondo T, Hasegawa T, Amizuka N, Kiyonari H, Shioi G, Abe M, Fukumoto S, Matsumoto T. Calcilytic ameliorates abnormalities of mutant calcium-sensing receptor knock-in mice mimicking autosomal dominant hypocalcemia (ADH). J Bone Miner Res 2015;61:727-33, 2. Yoshida S, Aihara K, Ikeda Y, Sumitomo-Ueda Y, Uemoto R, Ishikawa K, Ise T, Yagi S, Iwase T, Mouri Y, Sakari M, Matsumoto T, Takeyama K, Akaike M, Matsumoto M, Sata M, Walsh K, Kato S, Matsumoto T. Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling. Circulation 2013; 128:60-71 3. Aihara K, Azuma H, Akaike M, Ikeda Y, Sata M, Takamori N, Yagi S, Iwase T, Sumitomo Y, Kawano H, Yamada T, Fukuda T, Matsumoto T, Sekine K, Sat T, Nakamichi Y, Yamamoto Y, Watanabe T, Nakamura T, Oomizu A, Tsukada M, Hayashi H, Sudo T, Kato S, Matsumto T. Straindependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice. J Clin Invest 2007;117:1486-1489 4. Oshima T, Abe M, Asano J, Hara T, Kitazoe K, Sekimoto E, Tanaka Y, Shibata H, Hashimoto T, Ozaki S, Kido S, Inoue D, Matsumoto T. Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2. Blood 2005;106: 3160-3165. 5. Yoshizawa T, Handa Y, Uematsu Y, Takeda S, Sekine K, Yoshihara Y, Kawakami T, Arioka K, Sato H, Uchiyama Y, Masushige S, Fukamizu A, Matsumoto T, Kato S. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nature Genet 1997; 16:391-396 56


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