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The
th Annual Meeting of March 10-11, 2018 The Endocrine Society and The Diabetes Association of the R.O.C. (Taiwan)
SD1-1 FRAILTY AND SARCOPENIA IN OLDER ADULTS WITH DIABETES LIANG-KUNG CHEN Aging and Health Research Center, National Yang Ming University Center for Geriatrics and Gerontology, Taipei Veterans General Hospital
Diabetes mellitus is a prevalent condition of older adults, and the management may differ greatly from younger counterpart. The epidemiological study clearly showed that disability and dementia may be strong predictors than multimorbidity for adverse health outcomes in older people, which highlights the importance of prevention for disability and dementia. In particular, frailty and sarcopenia are two major foci to prevent disability. Sarcopenia, so-defined as the age-related loss of muscle mass plus loss of muscle strength and/ or loss of physical performance, is a newly defined disease entity. Age-related changes in body compostion is featured by the loss of bone mass, muscle mass and increase of fat mass. Nevertheless, sarcopenia is never a normal aging process, which is associated with mortality and morbidity. Diabetes, frailty and sarcopenia are highly interrelated conditions in older populations. Chronic inflammation and altered energy metabolism of cardiometabolic disease may accelerate muscle wasting. On the other hand, sarcopenia is also associated with higher risk of diabetes due to the loss of mitochondria. In modern clinical practice, adding consideration of disability and dementia into diabetes care is of critical importance. On the other hand, more attentions should be paid to diabetes patients with frailty and/or sarcopenia.
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