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II. Artículos Originales

I. INVESTIGACIÓN BÁSICA

I.I. MEDICINA REGENERATIVA DE LA SUPERFICIE OCULAR

I.I.I. BIOLOGÍA CELULAR DE LA SUPERFICIE OCULAR

Autores: Alberto Barros, Juan Queiruga-Piñeiro, Javier Lozano-Sanroma, Ignacio Alcalde, Juana Gallar, Luis

Fernández-Vega-Cueto, Jesús Merayo-Lloves.

Título: Small fiber neuropathy in the cornea of Covid-19 patients associated with ocular surface disease.

Revista: Ocul Surf. (2021). In Press (On line ahead of print) 30/10/2021. Índice de Impacto: 5.033. Q1, (7/62), Ophthalmology.

Autores: Natalia Pérez-López, Carla Martín, Beatriz García, María Pilar Solís-Hernández, David Rodríguez, Ignacio Alcalde, Jesús Merayo, Iván Fernández Vega and Luis M. Quirós.

Título: Alterations in the expression of the genes responsible for the synthesis of heparan sulfate in brains with Alzheimer’s disease.

Revista: J Neuropathol Exp Neurol. (2021) 80(5):446-456. doi: 10.1093/jnen/nlab028. IF: 3.685. Q2, (82/208), Clinical Neurology.

I.I.II. GLICÓMICA, MATRIZ Y SEÑALIZACIÓN

Autores: Otero-Guerra L, Gil-Alonso L, López-de Munain J, Del Romero-Guerrero J, Serra-Pladevall J, Vazquez F.

Título: Survey of diagnostic resources for STI in Spain.

Revista: Sexually Transmitted Infections Study Group GEITS. Enferm Infecc Microbiol Clin (Engl Ed). 2021 Oct;39(8):390-394. doi: 10.1016/j.eimce.2021.07.002. Epub 2021 Aug 3. PMID: 34362706.

Autores: Fernández-Martínez JL, Boga JA, de Andrés-Galiana E, Casado L, Fernández J, Menéndez C, García-Pérez A, Suarez NM, Sela MM, Vázquez F, Rodríguez-Guardado A.

Título: A Machine Learning Model for Evaluating Imported Disease Screening Strategies in Immigrant Populations.

Revista: Am J Trop Med Hyg. 2021 Sep 20:tpmd201443. doi: 10.4269/ajtmh.20-1443. Online ahead of print. PMID: 34544039.

Autores: Ordiales H, Vázquez-López F, Pevida M, Vázquez-Losada B, Vázquez F, Quirós LM, Martín C.

Título: Glycosaminoglycans Are Involved in the Adhesion of Candida albicans and Malassezia Species to Keratinocytes But Not to Dermal Fibroblasts.

Revista: Actas Dermosifiliogr (Engl Ed). 2021 May 18:S1578-2190(21)00161-X. doi: 10.1016/j.adengl.2021.05.002. Online ahead of print. PMID: 34052141.

Autores: Menéndez-Fraga MD, Alonso J, Cimadevilla B, Cueto B, Vazquez F.

Título: Does Skilled Nursing Facility Trigger Tool used with Global Trigger Tool increase its value for adverse events evaluation?

Revista: J Healthc Qual Res. 2021 Mar-Apr;36(2):75-80. doi: 10.1016/j.jhqr.2020.08.004. Epub 2021 Jan 26. PMID: 33509727.

Autores: Pérez-López N, García-Mesa Y, González-Fernández S, García-Suárez O, Merayo J, Fernández-Vega I,

Quirós L M.

Título: The Genes Encoding Small Leucine-Rich Proteoglycans Undergo Differential Expression Alterations in Colorectal Cancer, Depending on Tumor Location.

Revista: Cells. 2021 Aug 6;10(8):2002. doi: 10.3390/cells10082002.

I.II. NEUROBIOLOGÍA DE LA RETINA

I.II.I. NEUROPROTECCIÓN

Autores: Suárez-Barrio C, Del Olmo-Aguado S, García-Pérez E, Fernández-Vega-Cueto L, Fernández-Vega Cueto A, Baamonde-Arbaiza B, Fernández-Vega L, Merayo-Lloves J.

Título: Plasma Rich in Growth Factors Promotes Autophagy in ARPE19 Cells in Response to Oxidative Stress Induced by Blue Light.

Revista: Biomolecules. 2021 Jun 28;11(7):954. doi: 10.3390/biom11070954. Factor de Impacto: 4.879. Cuartil: Q2. ISSN: 2218-273X.

I.II.II. GENÉTICA OCULAR

Autores: Álvarez-Barrios A, Álvarez L, García M, Artime E, Pereiro R, González-Iglesias H.

Título: Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins.

Revista: Antioxidants. 2021, 10, 89.

Autores: The Genetics of Exfoliation Syndrome Partnership.

Título: Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye.

Revista: JAMA. 2021, 325(8):753-764.

Autores: Fernández AS, Rodríguez-González P, Álvarez L, García M, Iglesias HG, García Alonso JI.

Título: Multiple heart-cutting two dimensional liquid chromatography and isotope dilution tandem mass spectrometry for the absolute quantification of proteins in human serum.

Revista: Anal Chim Acta. 2021, 1184:339022.

Autores: Aranaz M, Costas-Rodríguez M, Lobo L, García M, González-Iglesias H, Pereiro R, Vanhaecke F.

Título: Homeostatic alterations related to total antioxidant capacity, elemental concentrations and isotopic compositions in aqueous humor of glaucoma patients.

Revista: Anal Bioanal Chem. 2021.

Autores: Fernández-Vega Cueto A, Álvarez L, García M, Álvarez-Barrios A, Artime E, Fernández-Vega Cueto L, Coca-Prados M, González-Iglesias H.

Título: Candidate Glaucoma Biomarkers: From Proteins to Metabolites, and the Pitfalls to Clinical Applications.

Revista: Biology (Basel). 2021, 10(8):763.

Autores: Valencia E, López A, Lobo L, González-Iglesias H, Pereiro R.

Título: Exploring the possibilities of calcium isotopic analysis in aqueous humor using a fast and miniaturized calcium isolation procedure.

Revista: J. Anal. At. Spectrom., 2021.

Autores: Lores-Padín A, Menero-Valdés P, Rodríguez-Penedo A, González-Iglesias H, Fernández B, Pereiro R.

Título: Synthesis of Size Monodisperse Water-Soluble Metal Nanoclusters for Protein Quantification by Elemental Mass Spectrometry.

Revista: Mater. Proc. 2021, 4(1), 43.

II. INVESTIGACIÓN TRASLACIONAL

MEDICINA REGENERATIVA DE LA SUPERFICIE OCULAR

Autores: M. Persinal-Medina, S. Llames, N. Vázquez, M. Chacón, A. Acebes-Huerta, E. Uribe, S. Alonso-Alonso,

C. Fernández-Vega González, B. Baamonde, L. Quirós, J. Merayo-Lloves, Meana.

Título: Xeno-free approach for the expansion of human adipose derived mesenchymal stem cells for ocular therapies.

Revista: Exp. Eye Res. 202 (2021). doi:10.1016/j.exer.2020.108358. IF: 3.467. Q2, Ophthalmology.

Autores: R.M. Sánchez-Ávila, N. Vázquez, M. Chacón, M. Persinal-Medina, A. Brea-Pastor, S. Berisa-Prado, L. Fernández-Vega-Cueto, E. Anitua, Á. Meana, J. Merayo-Lloves.

Título: Fibrin-plasma rich in growth factors membrane for the treatment of a rabbit alkali-burn lesion.

Revista: Int. J. Mol. Sci. 22 (2021). doi:10.3390/ijms22115564. IF: 5.924. Q1, Biochemistry & Molecular Biology -Q2, Chemistry, multidisciplinary.

Autores: S. Berisa-Prado, N. Vázquez, M. Chacón, M. Persinal-Medina, S. Alonso-Alonso, B. Baamonde, J.F.

Alfonso, L. Fernández-Vega-Cueto, J. Merayo-Lloves, Á. Meana.

Título: Mini cleanroom for the manufacture of advanced therapy medicinal products (Atmp): Bioengineered corneal epithelium.

Revista: Pharmaceutics. 13 (2021). doi:10.3390/pharmaceutics13081282. IF: 6.321. Q1, Pharmacology & Pharmacy-Scie.

III. INVESTIGACIÓN CLÍNICA

III.I. SEGMENTO ANTERIOR

Autores: Barros A, Queiruga-Piñeiro J, Lozano-Sanroma J, Alcalde I, Gallar J, Fernández-Vega Cueto L, Alfonso

JF, Quirós LM, Merayo-Lloves J.

Título: Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease.

Revista: Ocul Surf. 2021 Nov 12;23:40-48. doi: 10.1016/j.jtos.2021.10.010. Epub ahead of print. PMID: 34781021; PMCID: PMC8588585.

Autores: Berisa-Prado S, Vázquez N, Chacón M, Persinal-Medina M, Alonso-Alonso S, Baamonde B, Alfonso

JF, Fernández-Vega-Cueto L, Merayo-Lloves J, Meana Á.

Título: Mini Cleanroom for the Manufacture of Advanced Therapy Medicinal Products (ATMP): Bioengineered Corneal Epithelium.

Revista: Pharmaceutics. 2021 Aug 17;13(8):1282. doi: 10.3390/pharmaceutics13081282. PMID: 34452243; PMCID: PMC8401053.

Autores: Royo M, Jiménez Á, Martínez-Alberquilla I, Alfonso JF.

Título: Eight-year follow-up of Artiflex and Artiflex Toric phakic intraocular lens.

Revista: Eur J Ophthalmol. 2021 Jul 28:11206721211035617. doi: 10.1177/11206721211035617. Epub ahead of print. PMID: 34318738.

Autores: Fernández-Vega-Cueto L, Lisa C, Alfonso-Bartolozzi B, Madrid-Costa D, Alfonso JF.

Título: Intrastromal corneal ring segment implantation in paracentral keratoconus with perpendicular topographic astigmatism and comatic axis.

Revista: Eur J Ophthalmol. 2021 Jul;31(4):1540-1545. doi: 10.1177/1120672120952346. Epub 2020 Aug 24. PMID: 32830575.

Autores: Fernández-Vega-Cueto L, Alfonso-Bartolozzi B, Lisa C, Madrid-Costa D, Alfonso JF.

Título: Seven-year follow-up of posterior chamber phakic intraocular lens with central port design.

Revista: Eye Vis (Lond). 2021 Jun 11;8(1):23. doi: 10.1186/s40662-021-00247-1. PMID: 34112241; PMCID: PMC8194243.

Autores: Cuiña Sardiña R, Arango A, Alfonso JF, Álvarez de Toledo J, Piñero DP.

Título: Clinical evaluation of the effectiveness of asymmetric intracorneal ring with variable thickness and width for the management of keratoconus.

Revista: J Cataract Refract Surg. 2021 Jun 1;47(6):722-730. doi: 10.1097/j.jcrs.0000000000000525. PMID: 33278234.

Autores: Alfonso JF, Torquetti L, Fernández-Vega-Cueto L, Allan B, Poo-López A, Alfonso-Bartolozzi B, de la Cruz J, Monteiro T, Madrid-Costa D.

Título: Visual and Tomographic Outcomes of a 300° Arc-length ICRS Implantation in Moderate to Advanced Central Keratoconus.

Revista: J Refract Surg. 2021 Apr;37(4):249-255. doi: 10.3928/1081597X-20210115-01. Epub 2021 Apr 1. PMID: 34038659.

Autores: Alfonso JF, Lisa C, Fernández-Vega-Cueto L, Besteiro J, Alfonso-Bartolozzi B.

Título: Posterior chamber phakic intraocular lens with central-port design in 45- to 55-year-old patients: 1-year follow-up.

Revista: J Cataract Refract Surg. 2021 Apr 1;47(4):459-464. doi: 10.1097/j.jcrs.0000000000000486. PMID: 33181625.

Autores: Ruiz-Alcocer J, Martínez-Alberquilla I, Lorente-Velázquez A, Alfonso JF, Madrid-Costa D.

Título: Effect of defocus combined with rotation on the optical performance of trifocal toric IOLs.

Revista: Eur J Ophthalmol. 2021 Mar 11:11206721211002121. doi: 10.1177/11206721211002121. Epub ahead of print. PMID: 33706567.

Autores: Fernández-Vega Cueto A, Rodríguez-Una I, Rodríguez-Calvo PP, Alfonso JF.

Título: Femtosecond laser-assisted cataract surgery in shallow anterior chamber cases.

Revista: Int Ophthalmol. 2021 Feb;41(2):707-717. doi: 10.1007/s10792-020-01628-6. Epub 2020 Oct 24. PMID: 33099746.

Autores: Sanchez-Avila RM, Uribe-Badillo EE, Sanz JF, Muruzabal F, Jurado N, Alfonso-Bartolozzi B, Alfonso JF, Baamonde B, Anitua E, Merayo-Lloves J.

Título: Plasma rich in growth factors versus Mitomycin C in photorefractive keratectomy.

Revista: Medicine (Baltimore). 2021 Jan 22;100(3):e24139. doi: 10.1097/MD.0000000000024139. PMID: 33546027; PMCID: PMC7837908.

Autores: Monteiro T, Alfonso JF, Franqueira N, Faria-Correira F, Ambrósio R Jr, Madrid-Costa D.

Título: Comparison of clinical outcomes between manual and femtosecond laser techniques for intrastromal corneal ring segment implantation.

Revista: Eur J Ophthalmol. 2020 Nov;30(6):1246-1255. doi: 10.1177/1120672119872367. Epub 2019 Sep 10. PMID: 31505956.

III.II. RETINA

Autores: Fernández-Vega B, García M, Olivares L, Álvarez L, González-Fernández A, Artime E, Fernández-Vega Cueto A, Cobo T, Coca-Prados M, Vega JA, González-Iglesias H.

Título: The association study of lipid metabolism gene polymorphisms with AMD identifies a protective role for APOE-E2 allele in the wet form in a Northern Spanish population.

Revista: Acta Ophthalmologica 2020, 98(3):e282-e291.

Autores: Fernández-Vega B, Nicieza J, Álvarez-Barrios A, Álvarez L, García M, Fernández-Vega C, Vega JA,

González-Iglesias H.

Título: The Use of Vitamins and Coenzyme Q10 for the Treatment of Vascular Occlusion Diseases Affecting the Retina.

Revista: Nutrients 2020, 12(3), 723.

Autores: Fernández-Vega B, Álvarez L, García M, Artime E, Diñeiro Soto M, Nicieza J, Vega JA, Gonzá-

lez-Iglesias H.

Título: Association Study of MTHFR Polymorphisms with Nonarteritic Anterior Ischemic Optic Neuropathy in a Spanish Population.

Revista: Biomedicine Hub 2020, 5: 505431.

Autores: Diñeiro M, Capín R, Cifuentes GÁ, Fernández-Vega B, Villota E, Otero A, Santiago A, Pruneda PC, Castillo D, Viejo-Díaz M, Hernando I, Durán NS, Álvarez R, Lago CG, Ordóñez GR, Fernández-Vega Á, Cabanillas R, Cadiñanos J.

Título: Comprehensive genomic diagnosis of inherited retinal and optical nerve disorders reveals hidden syndromes and personalized therapeutic options.

Revista: Acta Ophthalmologica 2020.

Autores: Fernández-Vega González A, Muni R.

Título: The history of Pneumatic retinopexy: have we come full circle?

Revista: Acta Ophthalmol. 2021 Apr 14. DOI: 10.1111

Autores: Fernández-Vega González A, Fernández-Vega González C, Fernández-Vega Sanz B, Peláez MT, Me-

rayo-Lloves J.

Título: Bilateral fungal infection inducing a serpiginous-like picture.

Revista: Eur J Ophthalmol. 2021 May; 31(3). DOI: 101177.

Autores: Fernández-Vega Gonzalez A, Berger AR, Chow DR.

Título: Klebsiella pneumoniae endogenous endophthalmitis secondary to liver abscess syndrome.

Revista: International Journal of Ophthalmology. Vol 15, Number 1. In press.

III.III. GLAUCOMA

Autores: Fernandez-Vega Cueto A, Rodriguez-Una I, Rodriguez-Calvo PP, Alfonso JF.

Título: Femtosecond laser-assisted cataract surgery in shallow anterior chamber cases.

Revista: Int Ophthalmol. 2021;41:707-717.

Autores: Espinoza G, Castellanos-Castellano YA, Rodriguez-Una I, Acuña MF, Parra JC.

Título: Mid-term results of patterned laser trabeculoplasty as an adjunctive treatment for uncontrolled ocular hypertension and primary open angle glaucoma.

Revista: Int J Ophthalmol. 2021;14:1199-1204.

Autores: Rodríguez-Una I, Fernández-Vega Cueto A, Rodríguez-Calvo PP, Fernández-Vega Cueto L, Merayo-Lloves J, Alfonso JF.

Título: Long-term effectiveness and safety of early lensectomy in patients with pseudoexfoliation.

Revista: Ophthalmic. Res 2021;64(suppl 1):1–120.

Autores: Rodriguez-Una I, Fernández-Vega Cueto A, Rodriguez-Calvo PP, Garcia Montserrat, Fernandez-Vega Cueto L, Jesús Merayo-Lloves J, Alfonso JF.

Título: Early lensectomy in patients with pseudoexfoliation: long-term effectiveness and safety outcomes.

Revista: Eye. 2021. En revisión.

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