Catalog 2013
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CONTENTS
Cell & Molecular Biology........1 Genetics.......................6 Microbiology..................11 I mmunology.................14 Structural Biology...................17 Biophysics............................20 Computational Biology.........22 Chemistry.................................. 24 Plant and Marine Biology.....26 BIOS Series.................................. 29 Title Index.................................30 Author Index............................31 Order Form................................32
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Browse the Garland Science website! www.garlandscience.com You can find more information about the books in this catalog, learn about e-book and custom publishing options, and explore the Instructor and Student resource areas where you can search or browse the multimedia designed to accompany our textbooks.
CELL & MOLECULAR BIOLOGY
1
NEW EDITION
The Biology of Cancer, Second Edition Robert A. Weinberg, Whitehead Institute for Biomedical Research, MIT, USA
The Biology of Cancer is a textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. It presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments which give readers a sense of discovery and provides insights into the conceptual foundation underlying modern cancer biology. The new Second Edition has been thoroughly revised and updated to include major advances in cancer biology over the past 6 years. Updates include recent advances in the understanding of the tumor microenvironment, metastatic dissemination, tumor immunology, and new modes of therapy. Chapter 16: The Rational Treatment of Cancer has been expanded, as have the glossary and list of abbreviations and acronyms. Besides its value as a textbook, The Biology of Cancer is a useful reference for individuals working in biomedical laboratories, and for clinical professionals. Garland Science July 2013: 960pp: 584 illus Hb: 978-0-8153-4219-9: £105.00 Pb: 978-0-8153-4220-5: £55.00 CONTENTS: 1. The Biology and Genetics of Cells and Organisms 2. The Nature of Cancer 3. Tumor Viruses 4. Cellular Oncogenes 5. Growth Factors, Receptors, and Cancer 6. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer 7. Tumor Suppressor Genes 8. pRb and Control of the Cell Cycle Clock 9. p53 and Apoptosis: Master Guardian and Executioner 10. Eternal Life: Cell Immortalization and Tumorigenesis 11. Multistep Tumorigenesis 12. Maintenance of Genomic Integrity and the Development of Cancer 13. Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis 14. Moving Out: Invasion and Metastasis 15. Crowd Control: Tumor Immunology and Immunotherapy 16. The Rational Treatment of Cancer
Praise for previous edition
“ “
There is no comparable text in cancer biology...
”
Nature
Here, at last, we have a definitive textbook specifically devoted to the molecular and cell biology of cancer.
”
Bioscience Education
“
The Biology of Cancer is no doubt the definitive statement on its topic today
“
”
Science
Overall, this is a remarkable achievement that is by far the most comprehensive coverage of this field available.
”
Times Higher Education Supplement
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CELL & MOLECULAR BIOLOGY
NEW EDITION Essential Cell Biology, Fourth Edition Bruce Alberts, University of California, San Francisco, USA, Dennis Bray, University of Cambridge, UK, Karen Hopkin, Science Journalist and Biochemist, USA, Alexander Johnson, University of California, San Francisco, USA, Julian Lewis, Cancer Research UK, Martin Raff, University College London, UK, Keith Roberts, Emeritus, John Innes Centre, UK, and Peter Walter, University of California, San Francisco, USA
Essential Cell Biology provides an accessible introduction to the fundamental concepts of cell biology. Its lively writing and exceptional illustrations make it the ideal textbook for a first course in cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive, conceptual framework of the basic science that underlies our current understanding of biology. The Fourth Edition is thoroughly updated scientifically, and maintains the academic level and size of the previous edition. Garland Science November 2013: 870pp: 860 illus Hb: 978-0-8153-4454-4: £105.00 Pb: 978-0-8153-4455-1: £53.00
KEY FEATURES: • Completely updated throughout • New coverage of contemporary genomic methods, such as high-throughput sequencing • Concept headings descriptively introduce each CONTENTS: section 1. Introduction to Cells 2. Chemical Components of Cells 3. Energy, Catalysis, and • The art program emphasizes central concepts Biosynthesis 4. Protein Structure and Function without unnecessary detail 5. DNA and Chromosomes 6. DNA Replication, • “How We Know” sections in every chapter introduce experimental science Repair, and Recombination 7. From DNA to • Concept Questions interspersed throughout Protein: How Cells Read the Genome text and at the end of each chapter test students' 8. Control of Gene Expression 9. How Genes and Genomes Evolve 10. Manipulating Genes understanding • Panels concisely review basic science, principles, and Cells 11. Membrane Structure 12. Membrane Transport 13. How Cells Obtain pathways, as well as other topics • Key terms in text listed at the end of each Energy from Food 14. Energy Generation in chapter Mitochondria and Chloroplasts 15. Intracellular Compartments and Transport • Detailed, illustrated glossary • “Essential Concepts” review for each chapter 16. Cell Communication 17. Cytoskeleton • The authors are known worldwide for their 18. The Cell Division Cycle 19. Genetics, research, teaching, writing, and leadership in Meiosis, and the Molecular Basis of Heredity science and science education 20. Tissues and Cancer Praise for previous edition
“
[Essential Cell Biology] really ought to be an intrinsic part of every bioscience undergraduate's essential reading.
”
The Biochemist
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CELL & MOLECULAR BIOLOGY
3
Molecular Biology of the Cell, Fifth Edition Bruce Alberts, University of California, San Francisco, USA, Alexander Johnson, University of California, San Francisco, USA, Julian Lewis, Cancer Research UK, Martin Raff, University College London, UK, Keith Roberts, Emeritus, John Innes Centre, UK, and Peter Walter, University of California, San Francisco, USA
By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology. The hardback and paperback versions of Molecular Biology of the Cell used by most students includes Chapters 1-20 in printed format and a DVD-ROM which contains figures, animations, and the last five chapters of the text in PDF format. The Reference Edition, which provides the complete text of Chapters 1-25 in printed format along with the DVD-ROM, is ideal for libraries, laboratories, and researchers. Garland Science 2008: 1,392pp: 1,526 illus Hb: 978-0-8153-4105-5: £120.00 Pb: 978-0-8153-4106-2: £63.00 Reference Hb: 978-0-8153-4111-6: £135.00
CONTENTS: PART I INTRODUCTION TO THE CELL 1. Cells and Genomes 2. Cell Chemistry and Biosynthesis 3. Proteins PART II BASIC GENETIC MECHANISMS 4. DNA, Chromosomes, and Genomes 5. DNA Replication, Repair, and Recombination 6. How Cells Read the Genome: From DNA to Protein 7. Control of Gene Expression PART III METHODS 8. Manipulating Proteins, DNA, and RNA 9. Visualizing Cells PART IV INTERNAL ORGANIZATION OF THE CELL 10. Membrane Structure 11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes 12. Intracellular Compartments and Protein Sorting 13. Intracellular Vesicular Traffic 14. Energy Conversion: Mitochondria and Chloroplasts 15. Mechanisms of Cell Communication 16. The Cytoskeleton 17. The Cell Cycle 18. Apoptosis PART V CELLS IN THEIR SOCIAL CONTEXT 19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix 20. Cancer Chapters 21–25 available in printed format in the Reference Edition and on Media DVD-ROM in the Student Edition: 21. Sexual Reproduction: Meiosis, Germ Cells, and Fertilization 22. Development of Multicellular Organisms 23. Specialized Tissues, Stem Cells, and Tissue Renewal 24. Pathogens, Infection, and Innate Immunity 25. The Adaptive Immune System
Molecular Biology of the Cell: The Problems Book, Fifth Edition John Wilson, Baylor College of Medicine, USA, and Tim Hunt, Cancer Research, UK
The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter will review key terms, test for understanding basic concepts, and pose research based problems. The Problems Book has been designed to correspond with the first twenty chapters of Molecular Biology of the Cell, Fifth Edition. Garland Science 2008: 608pp: 826 illus Pb: 978-0-8153-4110-9: £28.00
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4
CELL & MOLECULAR BIOLOGY
NEW
Biology of Aging Roger McDonald, University of Califonia at Davis, USA
Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and longevity and describes how these basic principles help one to understand the uniquely human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. CONTENTS: 1. Basic Concepts in the Biology of Aging 2. Measuring Biological Aging 3. Evolutionary Theories of Longevity and Aging 4. Cellular Aging 5. Genetics of Longevity 6. Plant Senescence 7. Human Longevity 8. The Physiology of Human Aging 9. Age-Related Disease in Humans 10. Modulating Aging and Longevity Garland Science September 2013: 256pp: 241 illus Pb: 978-0-8153-4213-7 £42.00
NEW
Cell Signaling
Wendell Lim, University of California San Francisco, USA, Bruce Mayer, University of Connecticut Health Center, USA, and Tony Pawson, University of Toronto, Canada
Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are “wired” into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, which serves to illustrate the diverse ways in which these underlying principles and components are used by the cell to generate complex and sophisticated signal transduction networks. CONTENTS: 1. Overview of Signal Transduction 2. Principles and Mechanisms of Protein Interactions 3. Signaling Enzymes and Their Allosteric Regulation 4. Role of Post-Translational Modifications in Signaling 5. Subcellular Localization of Signaling Molecules 6. Small Soluble Signaling Mediators 7. Lipids and Enzymes that Modify Them 8. Information Transfer Across the Membrane 9. Regulated Protein Degradation 10. Modular Architecture and Evolution of Signaling Proteins 11. Signaling Devices in Networks 12. How Cells Make Decisions 13. Methods for Studying Signaling Proteins and Networks Garland Science November 2013: 368pp: 340 illus Pb: 978-0-8153-4244-1: £44.00
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CELL & MOLECULAR BIOLOGY
5
Cellular Signal Processing
An Introduction to the Molecular Mechanisms of Signal Transduction Friedrich Marks, Ursula Klingmüller and Karin Müller-Decker, all at University of Heidelberg and the German Cancer Research Center, Germany
Cellular Signal Processing is for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication.
“
Unlike other texts currently available, a common theme of data processing by cellular machinery runs through this book which makes it stand out favorably against the competition.
”
Garland Science 2008: 656pp: 428 illus Pb: 978-0-8153-4215-1: £48.00
Alexey Veraksa University of Massachusetts, USA
CONTENTS: 1. The “Brain of the Cell”: Data Processing by Protein Networks 2. Supplying the Network with Energy: Basic Biochemistry of Signal Transduction 3. Evolution of Cellular Data Processing 4. Basic Equipment: G-Proteins, Second Messengers, and Protein Kinases 5. Signal Transduction by Receptors with Seven Transmembrane Domains 6. Signal Transduction by Serine/ Threonine Kinase-Coupled Receptors 7. Signal Transduction by Tyrosine Kinase- and Protein Phosphatase-Coupled Receptors: A Late Invention of Evolution 8. Gene Transcription: The Ultimate Target of Signal Transduction 9. Signals Controlling mRNA Translation 10. Signal Transduction by Small G-proteins: The Art of Molecular Targeting 11. Mitogenactivated Protein Kinase and Nuclear Factor kB Modules 12. Cancer and Regulation of Cell Division 13. Signal Transduction by Proteolysis and Programmed Cell Death 14. Signal Transduction by Ions 15. Sensory Signal Processing 16. Signaling at Synapses: Neurotransmitters and Their Receptors 17. Putting Together the Pieces: The Approach of Systems Biology
Mathematics for Biological Scientists Mike Aitken, Bill Broadhurst, and Stephen Hladky, all at the University of Cambridge, UK
Mathematics for Biological Scientists is an undergraduate textbook which covers the mathematics necessary for biology students to understand, interpret and discuss biological questions.
“
Garland Science 2009: 482pp: 202 illus Pb: 978-0-8153-4136-9: £37.00
...this textbook will be useful for a whole range of students...it is a rich source of well-explained mathematical laws, theories and didactic examples.
”
CONTENTS: 1. Quantities and Units 2. Numbers and Equations 3. Tables, Graphs, and Functions 4. Shapes, Waves, and Trigonometry 5. Differentiation 6. Integration 7. Calculus: Expanding the Toolkit 8. The Calculus of Growth and Decay Processes 9. Descriptive Statistics and Data Display 10. Probability 11. Statistical Inference 12. Biological Modeling, Presenting Your Work, End of Chapter Questions, Answers to End of Chapter Questions
Guillaume Desanti University of Birmingham, UK
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GENETICS
NEW EDITION
Human Evolutionary Genetics, Second Edition Mark Jobling and Edward Hollox, both at University of Leicester, UK, Toomas Kivisild, University of Cambridge, UK, Chris Tyler-Smith and Matthew Hurles, both at Wellcome Trust Sanger Institute Cambridge, UK
Now in full color, this new edition of Human Evolutionary Genetics has been brought up-to-date with the many advances and discoveries made since the publication of the highly regarded first edition. The focus of the book is human genetic diversity: the mechanisms that generate it, how we study it, its implications in evolution, and its implications today. It will be an invaluable resource for anyone studying human evolution, genetic variation, population genetics, and biological anthropology. Garland Science June 2013: 650pp: 357 illus Pb: 978-0-8153-4148-2: £49.00
CONTENTS: 1. Introduction to Evolutionary Genetics Section I: How Do We Study Genetic Variation? 2. Structure, Function, and Diversity of the Genome 3. The Diversity of the Human Genome 4. Discovering and Assaying Genome Diversity Section II: How Do We Interpret Genetic Variation? 5. Processes Shaping Diversity 6. Making Inferences from Diversity Section III: Where and When Did Humans Originate? 7. Humans as Apes 8. Genetic Changes That Have Made Us Human 9. Origins of Modern Humans Section IV: How Did Humans Colonize the World? 10. The Distribution of Diversity 11. Colonization of the Old World and Australia 12. Agricultural Expansions 13. Into New Found Lands 14. What Happens When Populations Meet Section V: How Is An Evolutionary Perspective Helpful? 15. Understanding the Past and Future of Phenotypic Variation 16. Evolutionary Insights into Simple Genetic Diseases 17. Evolutionary Insights into Complex Diseases 18. Identity and Identification
Human Molecular Genetics, Fourth Edition Tom Strachan, Newcastle University, UK, and Andrew Read, University of Manchester, UK
Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. Garland Science 2010: 781pp: 610 illus Pb: 978-0-8153-4149-9: £50.00
“
This book is an excellent companion for students in human genetics or for researchers that want to gain background and knowledge in this field.
” Nature
CONTENTS: 1. Nucleic Acid Structure and Gene Expression 2. Chromosome Structure and Function 3. Genes in Pedigrees and Populations 4. Cells and Cell-Cell Communication 5. Principles of Development 6. Amplifying DNA: Cell-based DNA Cloning and PCR 7. Nucleic Acid Hybridization: Principles and Applications 8. Analyzing the Structure and Expression of Genes and Genomes 9. Organization of the Human Genome 10. Model Organisms, Comparative Genomics and Evolution 11. Human Gene Expression 12. Studying Gene Function in the Post-Genome Era 13. Human Genetic Variability and its Consequences 14. Genetic Mapping of Mendelian Characters 15. Mapping Genes Conferring Susceptibility to Complex Disease 16. Identifying Human Disease Genes and Susceptibility Factors 17. Cancer Genetics 18. Genetic Testing of Individuals 19. Pharmacogenetics, Personalized Medicine, and Population Screening 20. Genetic Manipulation of Animals for Modeling Disease and Investigating Gene Function 21. Genetic Approaches to Treating Disease
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GENETICS
7
NEW
Epigenetics Lyle Armstrong, Newcastle University, UK
Epigenetics will be an invaluable source of information about all aspects of this revolutionary subject for undergraduate students, graduate students, and professionals alike. It brings together the structure and machinery of epigenetic modification, how it controls cellular functions, and the evidence for the relationship between epigenetics and disease. A major focus is the role of epigenetics in stem cells. CONTENTS: 1. The Concept of Epigenetics Section 1: Epigenetic Modification 2. Transcription Machinery 3. DNA Packaging and Chromatin Architecture 4. Remodeling the Structure of Chromatin 5. DNA Methylation and Demethylation 6. Post-translational Histone Modification 7. Histone Modification Machinery 8. Control of Histone Modification Section 2: Epigenetic Control of Cellular Function 9. Epigenetic Control of Gene Expression 10. Epigenetic Control of the Mitotic Cell Cycle 11. Epigenetic Basis of Gene Imprinting 12. Epigenetic Control of Cellular Differentitation Section 3: The Epigenetic Basis of Disease 13. Epigenetic Predisposition to Disease 14. Epigenetics, Memory, and Cognitivie Dysfunction 15. Epigenetics and Cancer 16.The Stability of Epigenetic Modification Patterns Garland Science November 2013: 300pp: 150 illus Pb: 978-0-8153-6511-2: £45.00
Introduction to Genetics A Molecular Approach
Terry A. Brown, University of Manchester, UK
“
The progression from
The theme of Introduction to Genetics is the molecules through progression from molecules (DNA and genes) to processes to systems processes (gene expression and DNA replication) to systems (cells, organisms, and populations). This makes eminenet sense to a clear visual style progression reflects both the basic logic of life and similar to the one used the way in which modern biological research is for Genomes 3 should structured. Garland Science 2011: 538pp: 656 illus Pb: 978-0-8153-6509-9: £49.00
make this an attractive proposition for adoption.
”
Adrian Hall Sheffield Hallam University, UK
CONTENTS: PART 1 - GENES AS UNITS OF BIOLOGICAL INFORMATION 1. The Scope of Modern Genetics 2. DNA 3. Genes 4. Transcription of DNA to RNA 5. Types of RNA Molecule: Messenger RNA 6. Types of RNA Molecule: Noncoding RNA 7. The Genetic Code 8. Protein Synthesis 9. Control of Gene Expression PART 2 - GENES AS UNITS OF INHERITANCE 10. DNA Replication 11. Inheritance of Genes During Eukaryotic Cell Division 12. Inheritance of Genes in Bacteria 13. Inheritance of Genes During Virus Infection Cycles 14. Inheritance of DNA Molecules During Eukaryotic Sexual Reproduction 15. Inheritance of Genes During Eukaryotic Sexual Reproduction 16. Mutation and DNA repair 17. Inheritance of genes in Populations PART 3 - GENETICS IN OUR MODERN WORLD 18. Genes in Differentiation and Development 19. The Human Genome 20. Genes and Medicine 21. DNA in Forensics and Studies of Human History 22. Genes in Industry and Agriculture 23. The Ethical Issues Raised by Modern Genetics
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GENETICS
NEW Genome Stability Chromosome Repair and Recombination James Haber, Brandeis University, USA
Genome Stability: Chromosome Repair and Recombination describes the various mechanisms of repairing DNA damage by recombination, most notably the repair of chromosomal breaks. The text presents a definitive history of the evolution of molecular models of DNA repair, emphasizing current research. The book introduces the central players in recombination. An overview of the four major pathways of homologous recombinational repair is followed by a description of the several mechanisms of nonhomologous end-joining. Designed as a textbook for advanced undergraduate and graduate students with a molecular biology and genetics background, researchers and practitioners, especially in cancer biology, will also appreciate the book as a reference. CONTENTS: Prologue 1. Replication Re-Start and Recombination 2. Overview of Pathways 3. The RecA/Rad51 Strand Exchange Machine and the Search for Homology 4. Preparation of the RecA/Rad51 Filament 5. Single-Strand Annealing 6. Gene Conversion 7. “in vivo biochemistry” 8. Break-Induced Replication 9. Sister Chromatid Repair 10. Gene Targeting 11. Site-Specific Recombination 12. Meiosis: Cytology and Genetics 13. Molecular Meiotic Recombination 14. Holliday Junction Resolvases 15. Nonhomologous End-Joining 16. The Evolution of Molecular Models of Recombination Garland Science December 2013: 320pp: 313 illus Pb: 978-0-8153-4485-8: £50.00
Gene Control David Latchman, Birkbeck, University of London, UK
Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition.
Garland Science 2010: 448pp: 638 illus Pb: 978-0-8153-6513-6: £50.00 CONTENTS: 1. Levels of Gene Control 2. Structure of Chromatin 3. Role of Chromatin Structure in Gene Control 4. The Process of Transcription 5. Transcription Factors and Transcriptional Control 6. Post-transcriptional Processes 7. Post-transcriptional Regulation 8. Gene Control and Cellular Signaling Pathways 9. Gene Control in Embryonic Development 10. Control of Cell-type-specific Gene Expression 11. Gene Regulation and Cancer 12. Gene Regulation and Human Disease 13. Conclusions and Future Prospects
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GENETICS
9
Genome Duplication Melvin DePamphilis, National Institute of Child Health and Human Development, USA, and Stephen Bell, University of Oxford, UK
Genome Duplication provides a comprehensive and readable overview of the underlying principles that govern genome duplication in all forms of life, from the simplest cell to the most complex multicellular organism. Garland Science 2010: 450pp: 243 illus Pb: 978-0-415-44206-0: £54.00
“
CONTENTS: 1. Genomes 2. Life 3. Replication Forks 4. Replication Proteins: Leading Strand Synthesis 5. Replication Proteins: Lagging Strand Synthesis 6. Termination 7. Chromatin Assembly Cohesion and Modification 8. Replicons 9. Replication Origins 10. Origin Paradigms 11. Initiation 12. Cell Cycles 13. Checkpoints 14. Human Disease 15. Evolution of Cellular Replication Machineries
This book is an excellent reference for anyone who is interested in understanding the fundamentals of life. Summing up: Highly recommended.
”
C.A Klevickis James Madison University, USA
Statistical Genetics
Gene Mapping Through Linkage and Association Edited by Benjamin Neale, and Manuel Ferreira, both at Massachusetts General Hospital, USA, Sarah Medland, Virginia Commonwealth University, USA, and Danielle Posthuma, Vrije University, The Netherlands
Statistical Genetics is an advanced textbook focusing on conducting genome-wide linkage and association analysis in order to identify the genes responsible for complex behaviors and diseases. Garland Science 2007: 482pp: 64 illus Pb: 978-0-415-41040-3: £53.00
“
...well organised...will be a great starting place for anyone who wants to understand and, hopefully, get involved with research on the genetics of human complex traits...
”
J. K. Hewitt University of Colorado, USA
CONTENTS: 1. Introduction 2. DNA 3. Introduction to Biometrical Genetics 4. Introduction to Statistics 5. Statistical Power 6. Population Genetics and its Relevance to Gene Mapping 7. Principles of Linkage Analysis 8. IBD Estimation 9. Regression Methods for Linkage Analysis 10. Variance Components Linkage Analysis for Quantitative Traits 11. Extensions to Univariate Linkage Analysis 12. QTL Detection in Multivariate Data from Sibling Pairs 13. Factors Affecting Type I Error and Power of Linkage Analysis 14. Introduction to Association 15. Single-locus Association Models 16. Genome-wide Association 17. Haplotype Estimation 18. Multi-locus Association Models 19. Linkage Disequilibrium and Tagging 20. Haploview 21. Factors Affecting Type I Error and Power in Association 22. Resampling Approaches to Statistical Interference
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10 GENETICS Genomes 3 Terry A. Brown, University of Manchester, UK
The pioneering textbook Genomes put genomes, rather than genes, at the center of molecular genetics teaching. Genomes 3 provides the reader with a simple and elegant treatment of the field, covering molecular genetics from the basics through to genome expression and molecular phylogenetics. Garland Science 2006: 736pp: 550 illus Pb: 978-0-8153-4138-3: £54.00
“
...Genomes 3 is a useful book about molecular genetics and will no doubt be competing for the attention of students...
”
Bioscience Education Journal
CONTENTS: Part 1: Studying Genomes 1. Genomes, Transcriptomes and Proteomes 2. Studying DNA 3. Mapping Genomes 4. Sequencing Genomes 5. Understanding a Genome Sequence 6. Understanding How a Genome Functions Part 2: Genome Anatomies 7. Eukaryotic Nuclear Genomes 8. Genomes of Prokaryotes and Eukaryotic Organelles 9. Virus Genomes and Mobile Genetic Elements Part 3: How Genomes Function 10. Accessing the Genome 11. Assembly of the Transcription Initiation Complex 12. Synthesis and Processing of RNA 13. Synthesis and Processing of the Proteome 14. Regulation of Genome Activity Part 4: How Genomes Replicate and Evolve 15. Genome Replication 16. Mutations and DNA Repair 17. Recombination 18. How Genomes Evolve 19. Molecular Phylogenetics
The American Journal of
BioethicS The American Journal of Bioethics is the most widely-read bioethics journal around – published on paper and at bioethics.net. AJOB is #1 in 6 categories in the Journal Citation Index. Editor-in-Chief David Magnus, Ph.D. Stanford University
For more information, visit www.bioethics.net For subscription information, visit www.tandfonline.com/UAJB
Other AJOB journals available include: AJOB Neuroscience - www.tandfonline.com/UABN AJOB Primary Research - www.tandfonline.com/UABR
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MICROBIOLOGY 11 Microbiology
A Clinical Approach Anthony Strelkauskas, (deceased), Jennifer Strelkauskas, Doctor of Veterinary Medicine, Oregon, USA, and Danielle Moszyk-Strelkauskas, MD, Naval Medical Center, San Diego, USA
Microbiology: A Clinical Approach is a unique microbiology textbook for health science students studying microbiology. It is clinically-relevant and uses the theme of infection as its foundation.
“
...extensively illustrated throughout with photographs and easy to understand schematics. It is well-supported by a website for students including an E-Tutor, MicroMovies (to demonstrate flagellar movement for example), flashcards and lecture notes.
”
Garland Science 2010: 733pp: 630 illus Pb: 978-0-8153-6514-3: £50.00
The Biologist
CONTENTS: PART I FOUNDATIONS 1. What is Microbiology and Why Does it Matter? 2. Fundamental Chemistry for Microbiology 3. Essentials of Metabolism 4. An Introduction to Cell Structure and Host–Pathogen Relationships PART II DISEASE MECHANISMS 5. Requirements for Infection 6. Transmission of Infection, the Compromised Host, and Epidemiology 7. Principles of Disease 8. Emerging and Re-Emerging Infectious Diseases PART III CHARACTERISTICS OF DISEASE-CAUSING MICROORGANISMS 9. The Clinical Significance of Bacterial Anatomy 10. Bacterial Growth 11. Microbial Genetics and Infectious Disease 12. The Structure and Infection Cycle of Viruses 13. Viral Pathogenesis 14. Parasitic and Fungal Infections PART IV HOST DEFENSE 15. The Innate Immune Response 16. The Adaptive Immune Response 17. Failures of the Immune Response PART V CONTROL AND TREATMENT 18. Control of Microbial Growth with Disinfectants and Antiseptics 19. Antibiotics 20. Antibiotic Resistance PART VI MICROBIAL INFECTIONS 21. Infections of the Respiratory System 22. Infections of the Digestive System 23. Infections of the Genitourinary System 24. Infections of the Central Nervous System 25. Infections of the Blood 26. Infections of the Skin and Eyes PART VII THE BEST AND THE WORST; IMPORTANT ISSUES IN MICROBIOLOGY 27. Biotechnology 28. Bioterrorism
Viruses
Biology, Applications, and Control David R. Harper, Biocontrol Limited, UK
Viruses: Biology, Applications, and Control is a concise advanced undergraduate and graduate textbook covering the essential aspects of virology included in biomedical science courses. It is an updated and expanded version of David Harper’s Molecular Virology, Second Edition. Garland Science 2011: 346pp: 220 illus Pb: 978-0-8153-4150-5: £46.00
“
CONTENTS: 1. Virus Structure and Infection 2. Virus Classification and Evolution 3. Virus Replication 4. Immune Response and Evasion 5. Vaccines and Immunotherapy 6. Antiviral Drugs 7. Beneficial Use of Viruses 8. Emergence and Extinction of Viruses 9. Virus Culture, Detection and Diagnosis
...a good text for an advanced undergraduate course in virology.
”
Doodys Review
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12 MICROBIOLOGY Living in a Microbial World Bruce Hofkin, University of New Mexico, USA
Living in a Microbial World is a textbook written for students taking a general microbiology or microbiology-themed course for non-science majors. It teaches the essential concepts of microbiology through practical examples and a conversational writing style intended to make the material accessible to a wide audience. Garland Science 2010: 496pp: 413 illus Pb: 978-0-8153-4175-8: £45.00
“
It is a treasure trove of interesting anecdotes and facts which lecturers could use to spice up their lectures, or whet the appetite for more microbiology in keen students.
”
Immunology News CONTENTS: 1. Living in a Microbial World 2. The Chemistry of Life 3. The Cell: Where Life Begins 4. A Field Guide to the Microorganisms 5. The Microbiology of History and the History of Microbiology 6. An Introduction to Microbial Genetics 7. Microbial Metabolism and Growth 8. Microbial Evolution and the Origin of Life 9. An Ecologist’s Guide to Microbiology 10. The Disease Process: A Pathogen’s Perspective 11. Host Defense 12. Control of Microbial Growth 13. Epidemiology: Who, What, When, Where, and Why? 14. The Future is Here: Microorganisms and Biotechnology 15. Guess Who’s Coming to Dinner? Microorganisms and Food 16. Better Living with Microorganisms: Industrial and Applied Microbiology
Protozoa and Human Disease Mark F. Wiser, Tulane University, USA
Protozoa and Human Disease is a textbook for advanced undergraduate and graduate students studying parasitology and microbiology. It will also be a useful reference for public health and medical students. Garland Science 2010: 250pp: 113 illus Pb: 978-0-8153-6500-6: £39.00
“
...gives a clear overview of the medically most relevant protozoa...it has just the right size for detailed information without being overwhelming.
”
Immunology News
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CONTENTS: 1. Introduction to Medical Protozoology 2. Overview of Intestinal Protozoa 3. Entamoeba and Amebiasis 4. Giardiasis 5. Trichomonas vaginalis and Other Trichomonads 6. Balantidium coli and Blastocystis hominis 7. Kinetoplastids 8. African Trypanosomiasis 9. Trypanosoma cruzi and Chagas’ Disease 10. Leishmaniasis 11. General Apicomplexan Biology 12. Cryptosporidium 13. Monoxenous Intestinal Coccidia 14. Toxoplasma gondii 15. Malaria 16. Babesiosis 17. Free-Living Protozoa Affecting Human Health
MICROBIOLOGY 13 Case Studies in Infectious Disease Peter Lydyard, Royal Free and University College Medical School, UK, Michael Cole, Georgetown University Medical Center, USA, John Holton, Royal Free and University College Medical School, UK, Will Irving, University of Nottingham, UK, Nino Porakishvili, University of Westminster, UK, Pradhib Venkatesan, Nottingham University Hospital, UK, and Kate Ward, Royal Free and University College Medical School, UK
Case Studies in Infectious Disease presents forty case studies featuring the most important human infectious diseases worldwide. Written for students of microbiology and medicine, this book describes the natural history of infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis and treatment. Garland Science 2009: 608pp: 270 illus Pb: 978-0-8153-4142-0: £36.00
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It reads well and is an excellent textbook for medical students and a good source of illustrations, tables, and question ideas for teachers.
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Clinical Infectious Disease
CONTENTS: 1. Aspergillus fumigatus 2. Borellia burgdorferi and related species 3. Campylobacter jejuni 4. Chlamydia trachomatis 5. Clostridium difficile 6. Coxiella burnetti 7. Coxsackie B virus 8. Echinococcus spp. 9. Epstein-Barr virus 10. Escherichia coli 11. Giardia lamblia 12. Helicobacter pylori 13. Hepatitis B virus 14. Herpes simplex virus 1 15. Herpes simplex virus 2 16. Histoplasma capsulatum 17. Human immunodeficiency virus 18. Influenza virus 19. Leishmania spp. 20. Leptospira spp. 21. Listeria monocytogenes 22. Mycobacterium leprae 23. Mycobacterium tuburculosis 24. Neisseria gonorrhoeae 25. Neisseria meningitidis 26. Norovirus 27. Parvovirus 28. Plasmodium spp. 29. Respiratory syncytial virus 30. Rickettsia spp. 31. Salmonella typhi 32. Schistosoma spp. 33. Staphlococcus aureus 34. Streptococcus mitis 35. Streptococcus pneumoniae 36. Streptococcus pyogenes 37. Toxoplasma gondii 38. Trypanosoma spp. 39. Varicella-zoster virus 40. Wuchereria bancrofti
Biology of Disease Nessar Ahmed, Maureen Dawson, Chris Smith, all at Manchester Metropolitan University, UK, and Ed Wood (deceased)
Biology of Disease describes the biology of many of the human disorders and diseases that are encountered in a clinical setting. It is designed for first and second year students in biomedical science programs and will also be a highly effective reference for health science professionals.
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Taylor & Francis 2006: 600pp Pb: 978-0-7487-7210-0: £40.00
...this book is an excellent introduction to the subject of pathology, disease and laboratory diagnostics, which would be ideal for undergraduate students on biomedical science and related degrees.
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Alison Cottell University of Surrey, UK
CONTENTS: Preface • Glossary 1. The Nature and Investigation of Diseases 2. Pathogens and Virulence 3. Infectious Diseases and Treatments 4. The Immune System 5. Disorders of the Immune System 6. Transfusion and Transplantation 7. Disorders of the Endocrine System 8. Disorders of Water, Electrolytes and Urate Balances 9. Disorders of Acid-Base Balance 10. Diet and Disease 11. Disorders of the Gastrointestinal Tract, Pancreas, Liver and Gall Bladder 12. Toxicology 13. Disorders of the Blood 14. Disease of the Cardiovascular System 15. Genetic Diseases 16. Membrane, Organelle and cytoskeletal Disorders 17. Cancer 18. Aging & Disease • Case Study Discussions • Answers to Questions
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14 IMMUNOLOGY Janeway’s Immunobiology, Eighth Edition
Kenneth M. Murphy at the Washington University School of Medicine, St. Louis, USA
Janeway’s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, unifrom art program, and scientific accuracy. It introduces the immune system in all its aspects to undergraduates, and also provides a treatment of the subject that is comprehensive enough to be useful to graduate students interested in research, and to medical students focused on clinical applications. Garland Science 2011: 888pp: 599 illus Pb: 978-0-8153-4243-4: £50.00 CONTENTS: 1. Basic Concepts in Immunology 2. Innate Immunity: The First Lines of Defense 3. The Induced Responses of Innate Immunity 4. Antigen Recognition by B-cell and T-cell Receptors 5. The Generation of Lymphocytes Antigen Receptors 6. Antigen Presentation to T Lymphocytes 7. Signaling Through Immune System Receptors 8. The Development and Survival of Lymphocytes 9. T-cell Mediated Immunity 10. The Humoral Immune Response 11. Dynamics of Adaptive Immunity 12. The Mucosal Immune System 13. Failures of Host Defense Mechanisms 14. Allergy and Allergic Diseases 15. Autoimmunity and Transplantation 16. Evolution of the Immune System
Case Studies in Immunology, Sixth Edition A Clinical Companion
Raif Geha and Luigi Notarangelo, both at Harvard Medical School, USA
Case Studies in Immunology highlights major common disorders of immunity, including genetic disorders of the immune system, immune-complex diseases, immune-mediated hypersensitivity reactions, and autoimmune and alloimmune diseases. Garland Science 2011: 376pp: 200 illus Pb: 978-0-8153-4441-4: £36.00 CONTENTS: 1. X-linked Agammaglobulinemia 2. CD40 Ligand Deficiency 3. Activation-induced Cytidine Deaminase Deficiency 4. Common Variable Immunodeficiency 5. X-linked Severe Combined Deficiency 6. Adenosine Deaminase Deficiency 7. Omenn Syndrome 8. MHC Class II Deficiency 9. DiGeorge Syndrome 10. Acquired Immune Deficiency Syndrome (AIDS) 11. Graft- Versus-Host Disease 12. MHC Class I Deficiency 13. X-linked Lymphoproliferative Syndrome 14. Hemophagocytic Lymphohistocytosis 15. Chediak-Higashi Syndrome 16. Wiskott-Aldrich Syndrome 17. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy 18. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease 19. Autoimmune Lymphoproliferative Syndrome (ALPS) 20. Hyper IgE Syndrome 21. Ataxia Telangiectasia 22. Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome 23. X-linked Hypohydrotic Ectodermal Dysplasia and Immunodeficiency 24. Interferon-γ Receptor Deficiency 25. Severe Congenital Neutropenia 26. Chronic Granulomatous Disease 27. Leukocyte Adhesion Deficiency 28. Recurrent Herpes Simplex Encephalitis 29. Interleukin 1 Receptor-associated Kinase 4 Deficiency 30. Congenital Asplenia 31. Hereditary Angioedema 32. Factor I Deficiency 33. Deficiency of the C8 Complement Component 34. Hereditary Periodic Fever Syndromes 35. Systemic Onset Juvenile Idiopathic Arthritis 36. Rheumatoid Arthritis 37. Systemic Lupus Erythematosus 38. Mixed Essential Cryoglobulinemia 39. Crohn’s Disease 40. Multiple Sclerosis 41. Autoimmune Hemolytic Anemia 42. Myasthenia Gravis 43. Pemphigus Vulgaris 44. Celiac Disease 45. Acute Infectious Mononucleosis 46. Hemolytic Disease of the Newborn 47. Toxic Shock Syndrome 48. Lepromatous Leprosy 49. Acute Systemic Anaphylaxis 50. Allergic Asthma 51. Atopic Dermatitis 52. Drug-induced Serum Sickness 53. Contact Sensitivity to Poison Ivy
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IMMUNOLOGY 15 The Immune System, Third Edition Peter Parham, Stanford University, USA
The Immune System, Third Edition emphasizes the human immune system and synthesizes immunological concepts into a comprehensible, up-to-date, and reader-friendly account of how the immune system works. Garland Science 2009: 608pp: 513 illus Pb: 978-0-8153-4146-8: £46.00
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The writing style is both logical and eloquent and makes for easy reading, but it is the plethorea of simple, well annotated and cleverly chosen diagrams that transform this into such efficacious resource.
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Queens Medical Magazine
CONTENTS: 1. Elements of the Immune System and Their Roles in Defense 2. Innate Immunity 3. Principles of Adaptive Immunity 4. Antibody Structure and the Generation of B-Cell Diversity 5. Antigen Recognition by T Lymphocytes 6. The Development of B Lymphocytes 7. The Development of T Lymphocytes 8. T Cell-Mediated Immunity 9. Immunity Mediated by B Cells and Antibodies 10. The Body’s Defenses Against Infection 11. Failures of the Body’s Defenses 12. Over-reactions of the Immune System 13. Disruption of Healthy Tissue by the Immune Response 14. Vaccination to Prevent Infectious Disease 15. Transplantation of Tissues and Organs 16. Cancer and its Interaction with the Immune System
Case Studies in Allergic Disorders
Hans Oettgen and Raif Geha, both at Harvard Medical School, USA
Case Studies in Allergic Disorders describes the basic cellular and molecular mechanisms involved in the pathogenesis of commonly occurring allergic diseases and introduces the rationale for targeted intervention in these mechanisms in the treatment of allergy. Case Studies in Allergic Disorders is intended for medical students and undergraduate and graduate students in immunology as well as residents in internal medicine and pediatrics and fellows in allergy. Garland Science 2012: 176pp: 110 illus Pb: 978-0-8153-4436-0: £25.00 CONTENTS: 1. Acute Systemic Anaphylaxis 2. Allergic Asthma 3. Allergic Rhinitis 4. Allergic Diseases of the Eye 5. Atopic Dermatitis 6. Contact Dermatitis 7. Transfusion Reaction 8. Drug-induced Serum Sickness 9. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease (IPEX) 10. Hereditary Angioedema 11. Urticaria 12. Food Allergy 13. Eosinophilic Esophagitis 14. Allergic Bronchopulmonary Aspergillosis 15. Hypersensitivity Pneumonitis and Occupational Lung Disease 16. Venom Hypersensitivity 17. Hypereosinophilic Syndromes 18. Churg-Strauss Vasculitis 19. Aspirin Sensitivity and Nasal Polyposis 20. Mastocytosis
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16 IMMUNOLOGY Principles of Mucosal Immunology Society for Mucosal Immunology. Edited by Phillip D. Smith, University of Alabama at Birmingham, USA, Thomas T. MacDonald, Barts and the London School of Medicine and Dentistry, UK, and Richard S. Blumberg, Harvard Medical School, USA.
Principles of Mucosal Immunology is for graduate students, postdoctoral fellows and investigators in immunology and microbiology, and medical and dental students. 32 chapters contained in 7 sections present the basic and clinical aspects of the mucosal immune system, focusing on the major components of the mucosal barrier—the gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems. Garland Science 2012: 512pp: 220 illus Pb: 978-0-8153-4443-8: £47.00 CONTENTS: I. Development and Structure of Mucosal Tissue 1. Overview of the Mucosal Immune System Structure 2. Phylogeny of the Mucosal Immune System 3. Immunological and Functional Differences Among Individual Compartments of the Mucosal Immune System 4. Secreted Effectors of the Innate Mucosal Barrier II. Cellular Constituents of Mucosal Immune Systems and Their Function in Mucosal Homeostasis 5. Immune Function of Epithelial Cells 6. Intraepithelial Lymphocytes: Unusual T Cells at Epithelial Surfaces 7. Lymphocyte Populations within the Lamina Propria 8. Mucosal B Cells and Their Function 9. Secretory Immunoglobulins and Their Transport 10. Role of Dendritic Cells in Integrating Immune Responses to Lumenal Antigens 11. Intestinal Macrophages in Defense of the Mucosa 12. Mucosal Basophils, Mast Cells, and Eosinophils 13. M Cells and the Follicle-Associated Epithelium 14. Lymphocyte Trafficking from Inductive Sites to Effector Sites 15. Mucosal Tolerance III. Microbial Commensalism 16. Recognition of Microbial-Associated Molecular Patterns by Pattern Recognition Receptors 17. The Commensal Microbiota and Its Relationship to Homeostasis and Disease IV. Genitourinary Tract 18. The Immune System of the Genitourinary Tract 19. Mucosal Immune Responses to Microbes in the Genitourinary Tract V. Nose, Airways, Oral Cavity, and Eyes 20. Immunobiology of the Nose, Upper Airways, and Oral Cavity 21. Bronchial-associated Lymphoid Tissue and Immune-mediated Respiratory Diseases 22. The Ocular Surface as a Mucosal Immune Site VI. Infectious Diseases of Mucosal Surfaces 23. Mucosal Interactions with Enteropathogenic Bacteria 24. Helicobacter pylori Infection 25. Viral Infections 26. Infection-driven Periodontal Disease 27. Vaccine Strategies for Mucosal Infections VII. Specific Immune-mediated Diseases of Mucosal Surfaces 28. Celiac Disease 29. IgA Nephropathy 30. Mucosal Manifestations of Immunodeficiencies 31. Inflammatory Bowel Disease 32. Food Sensitive and Eosinophilic Enteropathies
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STRUCTURAL BIOLOGY 17 The Molecules of Life
Physical and Chemical Principles John Kuriyan, University of California, Berkeley, USA, Boyana Konforti, Cell Press, USA, David Wemmer, University of California, Berkeley, USA
The Molecules of Life is a new textbook that provides an integrated physical and biochemical foundation for undergraduate students majoring in biology of health sciences. The book integrates fundamental concepts in thermodynamics and kinetics with an introduction to biological mechanism at the level of molecular structure.
Garland Science 2012: 1032pp: 900 illus Pb: 978-0-8153-4188-8: ÂŁ53.00 CONTENTS: Part I. Biological Molecules 1. From Genes to RNA to Proteins 2. Nucleic Acid Structure 3. Glycans and Lipids 4. Protein Structure 5. Evolutionary Variation in Proteins Part II. Energy and Entropy 6. Energy and Intermolecular Forces 7. Entropy 8. Linking Energy and Entropy Part III. Free Energy 9. Free Energy 10. Chemical Potential and Drive to Equilibrium 11. Voltages and Free Energy Part IV. Molecular Interactions 12. Thermodynamics of Binding 13. Specificity of Macromolecular Recognition 14. Allostery Part V. Kinetics and Catalysis 15. Rates of Molecular Processes 16. Enzyme Catalysis 17. Diffusion and Transport Part VI. Assembly and Activity 18. Folding 19. Fidelity in DNA and Protein Synthesis
NEW EDITION
Principles of Proteomics, Second Edition Richard Twyman, WriteScience, UK
The Second Edition of Principles of Proteomics will be useful to those who need a broad overview of proteomics. It pulls together disparate information concerning the different proteomics technologies and their applications, and presents them in a simple and user-friendly manner. New sections deal with the increasingly prevalent field of subcellular proteomics, and the topic of protein chips is given special coverage. CONTENTS: 1. The Origin and Scope of Proteomics 2. Strategies for Protein Separation 3. Strategies for Protein Identification 4. Strategies for Protein Quantitation 5. The Analysis of Protein Sequences 6. Structural Proteomics 7. Interaction Proteomics 8. Protein Modification in Proteomics 9. Protein Microarrays 10. Applications of Proteomics Garland Science November 2013: 336pp: 313 illus Pb: 978-0-8153-4472-8: ÂŁ47.00
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18 STRUCTURAL BIOLOGY How Proteins Work Mike Williamson, University of Sheffield, UK
How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. It will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics and will also serve as a valuable resource for graduate students and researchers.
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...very good coverage of domain structure and the assembly of proteins from basic functional units, and an excellent discussions of the evolution of proteins...
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Garland Science 2011: 464 pp: 537 illus Pb: 978-0-8153-4446-9: £49.00
Choice
CONTENTS: 1. Protein Structure and Evolution 2. Protein Domains 3. Oligomers 4. Protein Interactions in Vivo 5. How Enzymes Work 6. Protein Flexibility and Dynamics 7. How Proteins Make Things Move 8. How Proteins Transmit Signals 9. Protein Complexes: Molecular Machines 10. Multi-Enzyme Complexes 11. Techniques for Studying Proteins
Introduction to Protein Structure, Second Edition Carl Branden (deceased), and John Tooze, Cancer Research UK
Introduction to Protein Structure provides an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full-color to illuminate the structural principles described in the text. Garland Science 1999: 410pp Pb: 978-0-8153-2305-1: £50.00
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The strength of the book lies in its beautiful art work and its logical dissection of the baffling complexities of protein structures…admirably concise, lucid and accurate presentations of difficult concepts… invaluable for students.
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Nature
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CONTENTS: PART 1 BASIC STRUCTURAL PRINCIPLES 1. The Building Blocks 2. Motifs of Protein Structure 3. Alpha-Domain Structures 4. Alpha/Beta Structures 5. Beta Structures 6. Folding and Flexibility 7. DNA Structures PART 2 STRUCTURE, FUNCTION AND ENGINEERING 8. DNA Recognition in Procaryotes by Helix-Turn-Helix Motifs 9. DNA Recognition by Eukaryotic Transcription Factors 10. Specific Transcription Factors Belong to a Few Families 11. An Example of Enzyme Catalysis: Serine Proteinases 12. Membrane Proteins 13. Signal Transduction 14. Fibrous Proteins 15. Recognition of Foreign Molecules by the Immune System 16. The Structure of Spherical Viruses 17. Prediction, Engineering, and Design of Protein Structures 18. Determination of Protein Structures
STRUCTURAL BIOLOGY 19 Biomolecular Crystallography
Principles, Practice, and Application to Structural Biology Bernhard Rupp, q.e.d. life science discoveries, California, USA
Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Deftly illustrated in full-color, the text describes mathematical and physical concepts in accessible and accurate language. Garland Science 2009: 800pp: 896 illus Hb: 978-0-8153-4081-2: £68.00
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This book will be an essential part of the library of any department that claims to make contributions to modern biology.
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Tom Blundell, Journal of Applied Crystallography
CONTENTS: I: FROM SEQUENCE TO CRYSTALS 1. Introduction: Preparing Your Study 2. Protein Structure 3. Protein Crystallization 4. Proteins for Crystallography II: FUNDAMENTALS OF PROTEIN CRYSTALLOGRAPHY 5. Crystal Geometry 6. Diffraction Basics 7. Statistics and Probability in Crystallography III: FROM CRYSTALS TO DATA 8. Instrumentation and Data Collection IV: DETERMINING YOUR STRUCTURE 9. Reconstruction of Electron Density and the Phase Problem 10. Experimental Phasing 11. Non-Crystallographic Symmetry and Molecular Replacement 12. Model Building and Refinement V: MAKING SENSE OF YOUR STRUCTURE 13. Structure Validation, Analysis, and Presentation
Protein Purification
Philip Bonner, Nottingham Trent University, UK
Protein Purification provides a guide to the major techniques, including non-affinity absorption techniques, affinity procedures, non-absorption techniques and methods for monitoring protein purity. There is an overview of protein strategy and equipment, followed by discussions and examples of each technique and its applications. The Basics Taylor & Francis 2007: 230pp: 63 illus Pb: 978-0-415-38511-4: £39.00 CONTENTS: 1. Protein Purification Strategy and Equipment 2. The Groundwork 3. Non-Affinity Absorption Techniques Used to Purify Proteins 4. Affinity Procedures Used to Purify Proteins 5. Non-Absorption Techniques for Purifying Proteins 6. Methods for Monitoring the Purity of Protein Solutions • Appendix 1. The Common Units Used in Biology • Appendix 2. The Answers to the Exercises • Appendix 3. Single Letter Code for Amino Acids • Appendix 4. The List of Suppliers
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20 BIOPHYSICS Physical Biology of the Cell, Second Edition Rob Phillips, California Institute of Technology, USA, Jane Kondev, Brandeis University, USA, Julie Theriot, Stanford University, USA, and Hernan Garcia, Princeton University, USA
Physical Biology of the Cell takes key cell biology experiments through a quantitative treatment to demonstrate how models can help refine our understanding and prediction of biological phenomena. Updated for the latest developments and now in full color, the second edition includes two new chapters on photosynthesis and pattern formation.
Garland Science 2012: 1057pp: 742 illus Pb: 978-0-8153-4450-6: £53.00 CONTENTS: Part I The Facts of Life 1. Why: Biology By the Numbers 2. What and Where: Construction Plans for Cells and Organisms 3. When: Stopwatches at Many Scales 4. Who: “Bless the Little Beasties” Part II Life at Rest 5. Mechanical and Chemical Equilibrium in the Living Cell 6. Entropy Rules! 7. Two-State Systems: From Ion Channels to Cooperative Binding 8. Random Walks and the Structure of Macromolecules 9. Electrostatics for Salty Solutions 10. Beam Theory: Architecture for Cells and Skeletons 11. Biological Membranes: Life in Two Dimensions Part III Life in Motion 12. The Mathematics of Water 13. A Statistical View of Biological Dynamics 14. Life in Crowded and Disordered Environments 15. Rate Equations and Dynamics in the Cell 16. Dynamics of Molecular Motors 17. Biological Electricity and the Hodgkin-Huxley Model 18. Light and Life Part IV The Meaning of Life 19. Network Organization in Space and Time 20. Biological Patterns: Order in Space and Time 21. Sequences, Specificity, and Evolution 22. Whither Physical Biology?
Introduction to Cell Mechanics and Mechanobiology Christopher R. Jacobs and Hayden Huang, both at Columbia University, USA, and Ronald Y. Kwon, University of Washington, USA
Introduction to Cell Mechanics and Mechanobiology teaches advanced undergraduate students a quantitative understanding of the way cells detect, modify, and respond to the physical properties within the cell environment. Coverage includes the mechanics of single molecule polymers, polymer networks, two-dimensional membranes, whole-cell mechanics, and mechanobiology, as well as primer chapters on solid, fluid, and statistical mechanics. Garland Science 2012: 350pp: 250 illus Pb: 978-0-8153-4425-4: £45.00 CONTENTS: 1. Introduction to Cell Mechanics 2. Introduction to Cell Biology 3. Primer to Solid Mechanics 4. Primer to Fluid Mechanics 5. Primer to Statistical Mechanics 6. Experimental Techniques and Analyses 7. Biopolymers 8. Polymer Networks and the Cytoskeleton 9. Biomembranes 10. Mechanobiology 11. Cellular Mechanotransduction
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BIOPHYSICS 21 Molecular Driving Forces, Second Edition
Statistical Thermodynamics in Biology, Chemistry, Physics and Nanoscience Ken A. Dill, Stony Brook University, USA, and Sarina Bromberg, Pescadero, California, USA
Molecular Driving Forces, Second Edition is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes.
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Garland Science 2011: 720pp: 690 illus Pb: 978-0-8153-4430-8: £54.00
Kenneth Dill and Sarina Bromberg were presented with the 2012 Emily M. Gray Award “for their impact on the education and professional formation of countless scientists by writing a textbook which is a landmark in molecular biophysics, Molecular Driving Forces".
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Biophysical Society
CONTENTS: 1. Principles of Probability 2. Extremum Principles Predict Equilibria 3. Heat, Work & Energy 4. Math Tools: Multivariate Calculus 5. Entropy & the Boltzmann Law 6. Thermodynamic Driving Forces 7. The Logic of Thermodynamics 8. Laboratory Conditions & Free Energies 9. Maxwell’s Relations & Mixtures 10. The Boltzman Distribution Law 11. The Statistical Mechanics of Simple Gases & Solids 12. What Is Temperature? What Is Heat Capacity? 13. Chemical Equilibria 14. Equilibria Between Liquids, Solids, & Gases 15. Solutions & Mixtures 16. The Solvation & Transfer of Molecules Between Phases 17. Physical Kinetics: Diffusion, Permeation & Flow 18. Microscopic Dynamics 19. Chemical Kinetics & Transition States 20. Coulomb’s Law of Electrostatic Forces 21. The Electrostatic Potential 22. Electrochemical Equilibria 23. Salt Ions Shield Charged Objects in Solution 24. Intermolecular Interactions 25. Phase Transitions 26. Cooperativity: The Hexlix-Coil, Isling & Landau Models 27. Adsorption, Binding & Catalysis 28. Multisite & Cooperative Ligand Binding 29. Bio & Nano Machines 30. Water 31. Water as a Solvent 32. Polymer Solutions 33. Polymer Elasticity & Collapse 34. Polymers Resist Confinement & Deformation
Fields, Forces, and Flows in Biological Systems Alan J. Grodzinsky, Massachusetts Institute of Technology, USA
Fields, Forces, and Flows in Biological Systems describes the fundamental driving forces for mass transport, electric current, and fluid flow as they apply to the biology and biophysics of molecules, cells, tissues, and organs. Basic mathematical and engineering tools are presented in the context of biology and physiology.
Garland Science 2011: 308pp: 200 illus Hb: 978-0-8153-4212-0: £54.00 CONTENTS: 1. Chemical Transport in Electrolyte Media 2. Electric Fields and Flows in Electrolyte Media 3. Electrochemical Coupling and Transport 4. Electrical Interaction Forces: From Intramolecular to Macroscopic 5. Newtonian Fluid Mechanics 6. Electrokinetics: MEMs, NEMs, and Nano-porous Biological Tissues 7. Rheology of Hydrated Biological Tissues and Polymeric Biomaterials
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22 COMPUTATIONAL BIOLOGY A First Course in Systems Biology Eberhard Voit, Georgia Institute of Technology, USA
A First Course in Systems Biology is a textbook that introduces the new paradigm of systems biology to advanced undergraduate and graduate students. Its main focus is on the development of computational models and their applications to diverse biological systems. The goal of the book is to provide the reader with sufficient background and access to methods to execute standard systems biology tasks, understand the modern literature and launch into specialized projects that address biological questions with theoretical and computational means. Garland Science 2012: 496pp: 250 illus Pb: 978-0-8153-4467-4: £46.00 CONTENTS: 1. Biological Systems 2. Introduction to Mathematical Modeling 3. Static Network Models 4. The Mathematics of Biological Systems 5. Parameter Estimation 6. Gene Systems 7. Protein Systems 8. Metabolic Systems 9. Signaling Systems 10. Population Systems 11. Integrative Analysis of Genome, Protein, and Metabolite Data 12. Physiological Modeling: the Heart as Example 13. Systems Biology in Medicine and Drug Development 14. Design of Biological Systems 15. Emerging Topics in Systems Biology
Phylogenomics A Primer
Rob DeSalle and Jeffrey Rosenfeld, both at American Museum of Natural History, USA
Phylogenomics introduces undergraduate and graduate students to the field of phylogenomics, the discipline that integrates evolutionary biology and genomics. The book presents an overview of the interlinking aspects of molecular biology, systematics, and bioinformatics; describes phylogenomic techniques such as PCR, CLUSTAL, and neighbor joining; and provides guidelines for navigating relevant databases such as GenBank, BLAST, and EDGAR. Garland Science 2012: 352pp: 160 illus Pb: 978-0-8153-4211-3: £38.00 CONTENTS: 1. Why Phylogenomics Matters 2. The Biology of Linear Molecules: DNA and Proteins 3. Evolutionary Principles – Populations and Trees 4. Databases 5. Homology and Pairwise Alignment 6. Multiple Alignments and Constructing Phylogenomic Matrices 7. Genome Sequencing and Annotation 8. Tree Building 9. Robustness and Rate Heterogeneity in Phylogenomics 10. Bayesian Analysis 11. Incongruence 12. Adapting Population Genetics to Genomics 13. Detecting Natural Selection in Genomes 14. Refining the Approach to Natural Selection at the Molecular Level 15. Genome-Level Analysis of Population Genetics 16. Genome Content Analysis 17. A Phylogenomic Perspective of Biological Diversity: Tree of Life, DNA Barcoding and Metagenomics 18. Microarrays in Evolutionary Studies and Functional Phylogenomics
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COMPUTATIONAL BIOLOGY 23 Practical Bioinformatics Michael Agostino, Pfizer Bioinformatics and Merrimack College, USA
Practical Bioinformatics is specifically designed for biology majors and is written for courses that have a practical, hands-on element. It contains many exercises to complement the straightforward and practical topics and is focused on the analysis of DNA, RNA, and protein sequences. It is designed to be the student’s first text for learning how to perform bioinformatics sequence analysis. Garland Science 2012: 394pp: 240 illus Pb: 978-0-8153-4456-8: £25.00 CONTENTS: 1. Introduction to Bioinformatics and Sequence Analysis 2. Introduction to Internet Resources 3. Introduction to the BLAST suite and BLASTN 4. BLASTP 5. Messenger RNA, cDNA, BLASTX and TBLASTN 6. Advanced Topics in BLAST 7. “Laboratory” Bioinformatics Tools 8. Protein Analysis 9. Explorations in short nucleotide sequences 10. MicroRNA and Pathway Analysis 11. Multiple Sequence Alignments 12. Browsing the Genome
Understanding Bioinformatics Marketa Zvelebil, The Institute of Cancer Research, UK, and Jeremy O. Baum, Imperial College London, UK
Suitable for advanced undergraduates and postgraduates, Understanding Bioinformatics provides a definitive guide to this vibrant and evolving discipline. Garland Science 2007: 798pp: 414 illus Pb: 978-0-8153-4024-9: £47.00
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...provides an outstanding introduction to the main bioinformatics problems and tools, well-balanced between applications to biological problems and theory behind data processing methods…
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Computer Methods and Programs in Bioinformatics
CONTENTS: Part 1: Background Basics 1. The Nucleic Acid World 2. Protein Structure 3. Dealing with Databases Part 2: Sequence Alignments 4. Producing and Analyzing Sequence Alignments 5. Pairwise Sequence Alignment and Database Searching 6. Patterns, Profiles, and Multiple Alignments Part 3: Evolutionary Processes 7. Recovering Evolutionary History 8. Building Phylogenetic Trees Part 4: Genome Characteristics 9. Revealing Genome Features 10. Gene Detection and Genome Annotation Part 5: Secondary Structures 11. Obtaining Secondary Structure from Sequence 12. Predicting Secondary Structures Part 6: Tertiary Structures 13. Modeling Protein Structure 14. Analyzing Structure-Function Relationships Part 7: Cells and Organisms 15. Proteome and Gene Expression Analysis 16. Clustering Methods and Statistics 17. Systems Biology Appendices : Background Theory • Appendix A. Probability, Information, and Bayesian Analysis • Appendix B. Molecular Energy Functions • Appendix C. Function Optimization
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24 CHEMISTRY Introductory Nanoscience
Physical and Chemical Concepts Masaru Kuno, University of Notre Dame, USA
Designed for upper-level undergraduate and graduate students, Introductory Nanoscience asks key questions about the quantitative concepts that underlie this new field. Using solved examples, this textbook shows to what extent we may predict the behavior and functionality of nanomaterials by understanding how their properties change with scale.
Garland Science 2011: 420 pp: 250 illus Pb: 978-0-8153-4424-7: ÂŁ42.00 CONTENTS: 1. Introduction 2. Structure 3. Length Scales 4. Types of Nanostructures 5. Absorption and Emission Basics 6. A Quantum Mechanics Review 7. Model Quantum Mechanics Problems 8. Additional Model Problems 9. Density of States 10. Bands 11. Time-Dependent Perturbation Theory 12. Interband Transitions 13. Synthesis 14. Characterization 15. Applications
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CHEMISTRY 25 Introduction to Bioorganic Chemistry and Chemical Biology David Van Vranken and Gregory A. Weiss both at University of California, Irvine, USA
Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Garland Science 2012: 478pp: 603 illus Pb: 978-0-8153-4214-4: ÂŁ48.00 CONTENTS: 1. Fundamentals of Chemical Biology 2. The Chemical Origins of Biology 3. DNA 4. RNA 5. Peptides and Proteins: Structure 6. Protein Function 7. Glycobiology 8. Terpenes & Polyketides 9. Signal Transduction
NEW Glycobiology Avadesha Surolia, Indian Institute of Science, India and Garima Gupta, Washington University in St. Louis, USA
Glycobiology integrates the basic biochemistry and structure of glycans with practical applications to chemical biology, molecular biology, protein science, biochemistry, and cell signaling. Geared toward advanced undergraduate and early graduate students, this textbook also highlights exciting topics such as disease metabolism, glycomics, and glycan biotechnology. Key pedagogical features include annotated references, end-of-chapter questions, and boxes with advanced material. The book will also be useful as a reference to researchers and lab practitioners. CONTENTS: 1. Overview of Glycobiology 2. Structures and Conformations of Monosaccharides and Oligosaccharides 3. Glycosylation Precursors, Glycan Processing Enzymes and Synthesis of Glycans. 4. N-linked Glycosylation 5. O-Linked Glycosylation 6. Glycolipids 7. Other Types of Glycosylation 8. Sialic Acids 9. Animal Lectins 10. Plant Lectins 11. Microbial Lectins 12. Ligand-Lectin Interactions in Protein Trafficking 13. Carbohydrate Recognition in Cell Addition and Signaling 14. Glycobiology and Immunity 15. Glycosylation Changes in Development and Cancer 16. Glycosylation and Neurobiology 17. Glycosylation Disorders and Diseases 18. Structural and Functional Glycomics 19. Glycans in Biotechnology 20. Common Methods Used to Study Glycobiology 21. Future Aspects of Glycobiology Garland Science November 2013: 300pp: 150 illus Pb: 978-0-8153-4461-2: ÂŁ51.00
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26 PLANT AND MARINE BIOLOGY Plant Biology Alison M. Smith, John Innes Centre, UK, George Coupland, Max Planck Institute, Germany, Liam Dolan, John Innes Centre, UK, Nicholas Harberd, University of Oxford, UK, Jonathan Jones, John Innes Centre, UK, Cathie Martin, John Innes Centre, UK, Robert Sablowski, John Innes Centre, UK, and Abigail Amey, Science Editor, London, UK
Plant Biology is a textbook written for upper-level undergraduate and graduate students. Plant Biology is a ‘where we are now’ account of plant science. It acknowledges the distinguished history of the subject, but its approach is strongly influenced by the radically new outlook that has emerged in the last twenty years. Many of the recent advances in Plant Biology the authors describe are useful in the understanding of modern biology as a whole. Garland Science 2009: 679pp: 657 illus Pb: 978-0-8153-4025-6: £46.00 CONTENTS: 1. Origins 2. Genomes 3. Cells 4. Metabolism 5. Development 6. Environmental Signals 7. Environmental Stress 8. Interactions with Other Organisms 9. Domestication & Agriculture
“
...abundantly and lavishly illustrated with original colour line drawings, and photographs and micrographs from leading plant laboratories and practitioners from around the world...
”
Nigel Chaffey Bath Spa University
Plant Biochemistry Caroline Bowsher, University of Manchester, UK, Martin Steer, University College Dublin, Ireland, and Alyson Tobin, University of St. Andrews, UK
Plant Biochemistry presents each topic from the cellular level to the ecological and environmental levels, placing it in the context of the whole plant. Biochemical pathways are represented as route maps, showing how one reaction follows another. These maps emphasize the dynamism and flexibility of the plant in the face of environmental challenges.
Garland Science 2008: 500pp: 332 illus Pb: 978-0-8153-4121-5: £48.00 CONTENTS: 1. Introduction to Plant Biochemistry 2. Approaches to Understanding Metabolic Pathways 3. Plant Cell Structure 4. Light Reactions of Photosynthesis 5. Photosynthetic Carbon Assimilation 6. Respiration 7. Synthesis and Mobilization of Storage and Structural Carbohydrates 8. Nitrogen and Sulfur Metabolism 9. Lipid Biosynthesis 10. Alkaloids 11. Phenolics 12. Terpenoids
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“
...much more then a suite of biochemical reactions and it offers a fascinating vision of the living plant cell...clearly a textbook to recommend without any hesitation to students and their teachers...
”
Michel Delseny Universite de Perpignan
PLANT AND MARINE BIOLOGY 27 Plant Cell Walls
From Chemistry to Biology Peter Albersheim and Alan Darvill, both at Complex Carbohydrate Research Center, University of Georgia, USA, Keith Roberts Emeritus, John Innes Centre, UK, Ron Sederoff, North Carolina State University, USA, and Andrew Staehelin Emeritus, University of Colorado, USA
Plant Cell Walls provides an in depth and diverse view of the microanatomy, biosynthesis and molecular physiology of these cellular structures, both in the life of the plant and in their use for bioproducts and biofuels. Plant Cell Walls is a textbook for upper-level undergraduates and graduate students, as well as a professional-level reference book.
Garland Science 2010: 430pp: 405 illus Hb: 978-0-8153-1996-2: ÂŁ66.00 CONTENTS: 1. The Cell Wall and Plant Anatomy 2. The Structural Polysaccharides of the Cell Wall and How They Are Studied 3. Biochemistry of the Cell Wall Molecules 4. Membrane Systems Involved in Cell Wall Assembly 5. Biosynthesis of Cell Wall Polymers 6. Architectural Principles and Variations 7. The Cell Wall in Growth and Development 8. Cell Walls and the Interaction of Plants with Microbes 9. Plant Cell Walls: A Renewable Material Resource
NEW Field Methods in Marine Science Scott Milroy, University of Southern Mississippi, USA
This book provides an authoritative guide and exhaustive reference of the methods most appropriate for field research, specifically within the marine sciences, and serves as an accessible introduction to the concepts and practice of modeling marine system dynamics. This text trains the next generation of field scientists to move from measurements to models, and to pursue information assimilation and synthesis. CONTENTS: Unit 1. First Principles Chapter 1. The Foundations of Scientific Inquiry Chapter 2. Introduction to Statistical Inference. Unit 2. Methods of Data Acquisition Chapter 3. General Considerations of Experimental Design. Chapter 4. Important Oceanographic Variables to Consider. Chapter 5. Common Hydrographic Census Methods. Chapter 6. Census Methods for Benthic Organisms. Chapter 7. Census Methods: Pelagic Organisms. Unit 3. Methods of Data Analysis Chapter 8. Analysis of Single-variant Dynamics. Chapter 9. Analysis of Multi-variant Dynamics. Unit 4. Methods of Data Assimilation (Modeling) Chapter 10. Fundamental Concepts in Modeling Chapter 11. Rules of Engagement Chapter 12. Modeling Simple Dynamics Chapter 13. Modeling Complex Dynamics Chapter 14. Modeling Large System Dynamics Appendix A. Symbols and Abbreviations. Appendix B. Numerical Constants and Equivalents for Common Units of Measure. Appendix C. Common Algorithms for the Estimation of Important Water Properties. Appendix D. Exercises in Unit Conversion. Appendix E. Oceanographic Sampling Equipment. Appendix F. A Compendium of Routine Oceanographic Methodologies Garland Science December 2013: 320pp: 220 illus Pb: 978-0-8153-4476-6: ÂŁ44.00
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28 PLANT AND MARINE BIOLOGY Marine Microbiology, Second Edition Ecology and Applications
Colin Munn, University of Plymouth, UK
Marine Microbiology brings together microbial biology and ecology to create an integrated approach that addresses environmental, human health, and economic concerns. The Second Edition takes into account many new discoveries in the field. It is ideally suited for upper-level undergraduate and graduate students, and researchers.
Garland Science 2011: 320pp: 131 illus Pb: 978-0-8153-6517-4: £46.00
“
...it is about as perfect as any text could get...
”
Leigh Owens James Cook University
CONTENTS: 1. Microbes in the Marine Environment 2. Methods in Marine Microbiology 3. Metabolic Diversity and Ecophysiology 4. Marine Bacteria 5. Marine Archaea 6. Marine Eukaryotic Microbes 7. Marine Viruses 8. Ocean Processes - Marine Microbes and the Carbon Cycle 9. Nutrient Cycles - Nitrogen, Sulphur and Phosphorus 10. Symbiotic Associations 11. Microbial Diseases of Marine Organisms 12. Marine Microbes as Agents of Human Disease 13. Microbial Aspects of Marine Biofouling, Biodeterioration and Pollution 14. Marine Microbes and Biotechnology
Biology of Fishes, Third Edition Quentin Bone, Marine Biological Association of the UK, Plymouth, UK, and Richard Moore, Coastal Carolina University, USA
The Third Edition of Biology of Fishes is chiefly about fish as remarkably efficient machines for coping with the many problems that life in water entails, and looks at many such special cases. Fishes form the largest group of vertebrates, with around 20,000 known species, and they display a remarkable diversity of size, shape, internal structure and ecology to cope with environments ranging from transient puddles to the abyssal depths of the sea Taylor & Francis 2008: 450pp: 280 illus Pb: 978-0-415-37562-7: £48.00 CONTENTS: 1. Diversity of Fishes 2. Fishes and their Habitats 3. Swimming 4. Buoyancy 5. Gas Exchange, Blood and the Circulatory System 6. Osmoregulation and Ion Balance 7. Food and Feeding 8. Reproduction and Life Histories 9. Endocrine Systems 10. Sensory Systems and Communication 11. Nervous System 12. Immune System 13. Behavior and Cognition 14. Fisheries and Aquaculture
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BIOS SERIES 29 BIOS INSTANT NOTES SERIES
ÂŁ20.00
Analytical Chemistry, First Edition
Pb: 978-1-85996-189-6
Animal Biology, First Edition
Pb: 978-1-85996-325-8
Biochemistry, Fourth Edition
Pb: 978-0-415-60845-9
Bioinformatics, Second Edition
Pb: 978-0-415-39494-9
Chemistry for Biologists, Third Edition
Pb: 978-0-415-68003-5
Developmental Biology, First Edition
Pb: 978-1-85996-153-7
Ecology, Second Edition
Pb: 978-1-85996-257-2
Genetics, Fourth Edition
Pb: 978-0-415-69314-1
Human Physiology, First Edition
Pb: 978-0-415-35546-9
Immunology, Third Edition
Pb: 978-0-415-60753-7
Inorganic Chemistry, Second Edition
Pb: 978-1-85996-289-3
Mathematics and Statistics for Life Scientists, First Edition
Pb: 978-1-85996-292-3
Medical Microbiology, First Edition
Pb: 978-1-85996-254-1
Medicinal Chemistry, First Edition
Pb: 978-1-85996-207-7
Microbiology, Fourth Edition
Pb: 978-0-415-60770-4
Molecular Biology, Fourth Edition
Pb: 978-0-415-68416-3
Neuroscience, Third Edition
Pb: 978-0-415-60769-8
Organic Chemistry, Second Edition
Pb: 978-1-85996-264-0
Physical Chemistry, First Edition
Pb: 978-1-85996-194-0
Plant Biology, Second Edition
Pb: 978-0-415-35643-5
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30 TITLE INDEX A First Course in Systems Biology. . . . . . .22 Biology of Aging . . . . . . . . Biology of Cancer, The . . . . . . . . Biology of Disease.. . . . . . . . . Biology of Fishes. . . . . . . . . . Biomolecular Crystallography.. . . . . . .
. . . . . . . . . . . . . . . . . . . . . . .
Case Studies in Allergic Disorders . Case Studies in Immunology. . . . . . Case Studies in Infectious Disease . . . Cell Signaling . . . . . . . . . . . . Cellular Signal Processing. . . . . . .
. . . . . . . . .
. . . . .
. 4 . 1 . 13 . 28 . 19
. .15 . . 14 . . 13 . . 4 . . 5
Epigenetics . . . . . . . . . . . . . . . . . . 7 Essential Cell Biology . . . . . . . . . . . . . 2 Fields, Forces, and Flows in Biological Systems . . . .21 Field Methods in Marine Science. . . . . . . . . 27 Gene Control. . . . . Genome Duplication. . Genome Stability . . . Genomes 3. . . . . . Glycobiology . . . . .
. . . . .
. . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . 8 . . . . . . 9 . . . . . . . 8 . . . . . . 10 . . . . . . 25
How Proteins Work . . . . . . . . . . . 18 Human Evolutionary Genetics. . . . . . . . . . 6 Human Molecular Genetics.. . . . . . . . . . . . . . 6 Immune System, The . . . . . . . . . . . . . 15 BIOS INSTANT NOTES IN Analytical Chemistry . . . . . . . . . . . . . 29 Animal Biology . . . . . . . . . . . . . . 29 Biochemistry. . . . . . . . . . . . . . . . 29 Bioinformatics . . . . . . . . . . . . . .29 Chemistry for Biologists . . . . . . . . . . . 29 Developmental Biology . . . . . . . . . . . . . 29 Ecology. . . . . . . . . . . . . . . 29 Genetics.. . . . . . . . . . . . . . . . . . 29 Human Physiology . . . . . . . . . . . . . . 29 Immunology . . . . . . . . . . . . . . . . 29 Inorganic Chemistry . . . . . . . . . . . 29 Mathematics and Statistics for Life Scientists . . 29 Medical Microbiology . . . . . . . . . . . . 29 Medicinal Chemistry . . . . . . . . . . 29 Microbiology . . . . . . . . . . . . . . . 29 Molecular Biology . . . . . . . . . . . . . . . 29 Neuroscience . . . . . . . . . . . . . . . . . . . . 29 Organic Chemistry . . . . . . . . . . . . . . . . . . . . 29 Physical Chemistry . . . . . . . . . . . . . . . . . . . . 29 Plant Biology . . . . . . . . . . . . . . . . . . . 29
Introductory Nanoscience. . . . . . . . . . . . . . 24 Introduction to Bioorganic Chemistry and Chemical Biology . .25 Introduction to Cell Mechanics and Mechanobiology . . . 20 Introduction To Genetics. . . . . . . . . . . . . . . . 7 Introduction to Protein Structure . . . . . . . . . . 18 Janeway’s Immunobiology . . . . . . . . . . 14 Living in a Microbial World . . . . . . . . . . . . . .
12
Marine Microbiology . . . . . . . . . . . . . . 28 Mathematics for Biological Scientists . . . . . . . . 5 Microbiology.. . . . . . . . . . . . . . 11 Molecular Biology of the Cell . . . . . . . . . . . . 3 Molecular Biology of the Cell - Reference Edition . . . 3 Molecular Biology of the Cell - The Problems Book . . . 3 Molecular Driving Forces . . . . . . . . . . . . 21 Molecules of Life, The . . . . . . . . . . . 17 Phylogemonics . . . . . . . . . . . Physical Biology of the Cell . . . . . . . . . . Plant Biochemistry . . . . . . . . . . . . . . Plant Biology . . . . . . . . . . . . . . . Plant Cell Walls . . . . . . . . . . . . . . Practical Bioinformatics . . . . . . . . . . . . . . Principles of Mucosal Immunology . . . . . . . . . Principles of Proteomics. . . . . . . . . . . . Protein Purification . . . . . . . . . . . . Protozoa and Human Disease . . . . . . . . . . .
22 20 26 26 27 23 16 17 19 12
Statistical Genetics . . . . . . . . . . . . . 9 Understanding
Bioinformatics
.
.
.
.
.
.
.
.
23
Viruses . . . . . . . . . . . . . . . . . . . 11
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AUTHOR INDEX 31 Agostino, Michael . . . . .23 Ahmed, Nessar . . . . 13 Aitken, Mike . . . . . . 5 Albersheim, Peter . . . . . . 27 Alberts, Bruce . . . . . 2, 3 Amey, Abigail . . . . . 26 Armstrong, Lyle . . . . . . . . 7 Baum, Jeremy O. . . . . . 23 Bell, Stephen . . . . . . . 9 Blumberg, Richard S. . . . . . 16 Bone, Quentin . . . . . . 28 Bonner, Philip . . . . . . . 19 Bowsher, Caroline . . . 26 Branden, Carl . . . . . 18 Bray, Dennis . . . . . . . . 2 Broadhurst, Bill . . . . . . 5 Bromberg, Sarina . . . . . 21 Brown, Terry A. . . . . . . 7, 10 Cole, Michael . . . . . . . .13 Coupland, George . . . . . 26 Darvill, Alan . . . . Dawson, Maureen . . . . DePamphilis, Melvin . . . DeSalle, Rob . . . . . . Dill, Ken A. . . . . Dolan, Liam . . . . .
. 27 . 13 . . 9 . 22 . 21 . 26
Ferreira, Manuel . . . . . . 9 Garcia, Hernan . . Geha, Raif . . . . Grodzinsky, Alan J. Gupta, Garima . . .
. . . .
. . . . 14, . . . . . . .
20 15 21 25
Jacobs, Christopher R. . . . 20 Jobling, Mark . . . . . 6 Johnson, Alexander . . . 2, 3 Jones, Jonathan . . . . 26 Kivislid, Toomas . . . . . Klingm端ller, Ursula . . . Kondev, Jane . . . . . Konforti, Boyana . . . Kuno, Masaru . . . . Kuriyan, John . . . Kwon, Ronald Y . . . Latchman, David Lewis, Julian . . Lim, Wendell . . . Lydyard, Peter. .
. . . .
. . . . . . .
. 6 . 5 20 17 24 17 20
. . . 8 . . 2, 3 . . . . . 4 . . . .13
MacDonald, Thomas T. . . . 16 Marks, Friedrich . . . . . . 5 Martin, Cathie . . . . . . 26 Mayer, Bruce . . . . . . . . . 4 McDonald, Roger . . . . . . . 4 Medland, Sarah . . . . . . . 9 Milroy, Scott . . . . . . . . 27 Moore, Richard . . . . . . . 28 Moszyk-Strelkauskas, Danielle . . 11 M端ller-Decker, Karin . . . . . 5 Munn, Colin . . . . . . . 28 Murphy, Kenneth M. . . . 14
Sederoff, Ron . . . Smith, Alison M . . Smith, Chris . . . Smith, Phillip D. . . Staehelin, Andrew. . Steer, Martin . . . Strachan, Tom . . . Strelkauskas, Anthony Strelkauskas, Jennifer Surolia, Avadesha . . . Theriot, Julie . . . Tobin, Alyson . . Tooze, John . . . . Twyman, Richard . . Tyler-Smith, Chris .
. . 27 . . . 26 . . 13 . . . 16 . . . 27 . . 26 . . . . 6 . . . . 11 . . . 11 . . . . 25
. . . . 20 . . . 26 . . . . 18 . . . . . .17 . . . . 6
Van Vranken, David . . . . .25 Venkatesan, Pradhib . . . 13 Voit, Eberhard . . . . . . . 22 Walter, Peter . . . . . . 2, 3 Ward, Kate . . . . . . . 13 Weinberg, Robert A. . . . 1 Weiss, Gregory A . . . . .25 Wemmer, David . . . . .17 Williamson, Mike . . . . . 18 Wilson, John . . . . . . . 3 Wiser, Mark F. . . . . . . . . 12 Wood, Ed . . . . . . . . . . 13 Zvelebil, Marketa . . . . . 23
Neale, Benjamin . . . . . . . 9 Notarangelo, Luigi . . . . . . 14 Oettgen, Hans . . . . . . . 15
Haber, James . . . . . . . 8 Harberd, Nicholas . . . . . 26 Harper, David R. . . . . . . 11 Hladky, Stephen . . . . . 5 Hofkin, Bruce . . . . . 12 Hollox, Edward . . . . . . . 6 Holton, John . . . . 13 Hopkin, Karen . . . . . . . . 2 Huang, Hayden . . . . . 20 Hunt, Tim . . . . . . . 3 Hurles, Matthew . . . . . 6
Parham, Peter . . . . Pawson, Tony . . . . . . Phillips, Rob . . . . . . Porakishvili, Nino. . . . . Posthuma, Danielle. . .
. . . .
15 . 4 20 13 . 9
Irving, Will . . . . . . 13
Sablowski, Robert . . . . . . 26
Raff, Martin . . . . . . . . 2, 3 Read, Andrew . . . . . . . 6 Roberts, Keith . . . . 2, 3, 27 Rosenfeld, Jeffrey . . . . 22 Rupp, Bernhard. . . . . . 19
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NEW FROM GARLAND SCIENCE • Biology of Aging pg.4 • Case Studies in Allergic Disorders pg.15 • Cell Signaling pg.4 • Essential Cell Biology, Fourth Edition pg.2 • Epigenetics pg.7 • Field Methods in Marine Science pg.27 • Genome Stability pg.8 • Glycobiology pg.24 • Human Evolutionary Genetics, Second Edition pg.6 • Introduction to Bioorganic Chemistry and Chemical Biology pg.25 • Introduction to Cell Mechanics and Mechanobiology pg.20 • Phylogenomics: A Primer pg.22 • Physical Biology of the Cell, Second Edition pg.20 • Principles of Proteomics, Second Edition pg.17 • The Biology of Cancer, Second Edition pg.1
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