LabMedica International January 2025

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Annual Review 2024

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EDITORIAL BOARD

Graham Beastall United Kingdom

Hernán Fares Taie Argentina

Bernard Gouget France

Maurizio Ferrari Italy

Tahir S. Pillay South Africa

Andreas Rothstein Colombia

Praveen Sharma India

Rosa I. Sierra-Amor Mexico

Peter Wilding United States

Andrew Wootton United Kingdom

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LabMedica

TOP 100 DIAGNOSTICS ADVANCES OF 2024

JANUARY

Placental Swabs Found Most Effective for Detection of Maternal Sepsis

Anew study of microbiology specimens used to investigate maternal sepsis has demonstrated that placental swabs could play a vital role in informing antimicrobial therapy decisions. The study by researchers from University of Limerick (Limerick, Ireland; ul.ie/ehs/ medicine) found that placental swabs are valuable in identifying potential pathogens from the uterine cavity, which is the most common site of perinatal infections. This discovery is crucial as placental swabs are not routinely examined in many hospitals, meaning vital information that could influence the treatment of these infections might be overlooked. The research team’s findings were published in the journal PLOS ONE.

Test Screens for Genetic Diseases in Fetuses

An innovative screening test uses a blood sample from expectant mothers to analyze all the genes in the fetus, making it be possible to screen pregnant women for serious genetic diseases in their unborn children. The new test, named desNIPT, was developed by a research team from the University of Southern Denmark (Odense, Denmark) and has been proven capable of detecting mutations in fetal genes, which are often the root of serious congenital diseases. This new test builds upon the foundations of the first-generation Non-Invasive Prenatal Test (NIPT), significantly enhancing its capabilities.

Handheld White Blood Cell Tracker to Enable Rapid Testing for Infections

Anew groundbreaking innovative device can rapidly count a person’s WBC with a single drop of blood, similar to the way glucometers rapidly scan for blood sugar levels, enabling rapid testing and improved triaging for infections. Called the CytoTracker Leukometer, the device developed by researchers at Rutgers startup RizLab Health Inc. (Princeton, NJ, USA; www.rizlabhealth.com) can quickly aid the detection of elevated or reduced WBC counts. The device has undergone comprehensive testing, comparing its performance with conventional lab benchtop hematology analyzers used for standard blood tests.

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These trials confirmed that the CytoTracker Leukometer is at least 97% accurate, thereby meeting established clinical standards.

One-Minute COVID-19 Test Adaptable for Detecting Other Viruses with Spike-Like Proteins

Researchers at the National Institute of Advanced Industrial Science and Technology (AIST, Ibaraki, Japan; www.aist.go.jp) have developed a glowing test, based on their belief that an imidazopyrazinone-type (IPT) luciferin can react with the SARS-CoV-2 spike protein, which allows the virus particles to invade cells and cause COVID-19. Importantly, the researchers found that this luciferin could deter-

mine the quantity of the spike protein present in saliva with the same level of accuracy as a method used in vaccine research, but much faster - delivering results in just one minute, a significant improvement over existing rapid point-of-care tests. The findings were published in ACS Central Science on January 17.

Novel Screening Test Capable of Identifying 18 Early-Stage Cancers

Agroundbreaking test from Novelna Inc. (Palo Alto, CA, USA; www.novelna.com) can identify 18 types of early-stage cancers across various major organs in the human body. The groundbreaking test leverages a gender-specific panel of 10 proteins, providing a

significant advancement in the ongoing battle against cancer. This test’s focus on gender-specific proteins allows for unparalleled sensitivity and specificity, acknowledging the unique biological differences in cancer development between men and women. The test could be a game-changer in cancer screening by saving a significant number of lives.

Measuring Chemotherapy

Results in Bone Cancer

The calculation of Percent Necrosis (PN) — the proportion of a tumor considered inactive or “dead” following chemotherapy — serves as a vital predictor of survival outcomes in osteosarcoma, a type of bone cancer. A machine learning model created and trained by researchers at Johns Hopkins Medicine (Baltimore, MD, USA) to calculate PN has shown that its calculation was 85% correct when compared to the results of a musculoskeletal pathologist, with the accuracy improving to 99% upon excluding an outlier. The “weakly supervised” machine learning model does not require extensive annotated data for training. By doing so, a pathologist would only need to provide partially annotated whole-slide images, significantly easing their workload.

FEBRUARY

Handheld Device Detects Fentanyl in Urine in Seconds

Researchers at University of Texas at Dallas (Richardson, TX, USA; be.utdallas.edu) have developed a first-of-its-kind, handheld device that is capable of accurately detecting fentanyl in urine within seconds. The device contains an electrochemical sensor that operates by generating electrical signals from chemical reactions. The team’s proof-of-concept device can detect trace amounts of fentanyl with 98% accuracy, bypassing the need for expensive and time-consuming lab analyses. A study demonstrating the device was published in ACS Applied Materials & Interfaces

15-Minute Multiplex Molecular Test to Detect STI at Point-of-Care

Anew rapid, portable molecular STI test promises to deliver immediate results to patients and providers, enabling prompt treatment and potentially improving health outcomes, especially for patients who might otherwise postpone or forego testing. Detect (Guilford, CT, USA; www.detect.com) is gearing up to begin clinical validations for its 15-minute multiplex molecular STI test, based on a technology initially developed for tackling the COVID-19 pandemic. This testing relies on loop-mediated isothermal amplification (LAMP) and a simple instrument, aiming for affordability, speed, and ease of use. The test also incorporates proprietary biologics like

Top 100 Diagnostics Advances

enzymes, which are self-designed and manufactured by Detect, leading to faster and more accurate results.

Electrochemical Sensors with Next-Generation Coating Advances Precision Diagnostics at POC

Researchers at Wyss Institute at Harvard University (Boston, MA, USA; www. wyss.harvard.edu), in collaboration with several institutes in Korea, have significantly advanced electrochemical diagnostic sensing. They have developed a new nanocomposite porous antifouling coating that is one micrometer thick – about 100 times thicker than previous coatings. This increased thickness, coupled with an engineered porous structure, allows for the integration of a higher number of biomarker-detecting probes into the sensors. When tested with patient samples, the new sensor demonstrated 3.75 to 17 times higher detection sensitivities compared to a previous sensor fabricated with the same detection systems but using the team’s thinner, non-porous coating. It also accurately distinguished between positive and negative samples with 100% specificity. The findings were published on February 6 in Nature Communications.

Blood Tests Predict Lymphoma Outcomes

Aresearch team from Roswell Park Comprehensive Cancer Center (Buffalo, NY, USA; www.roswellpark.org) and Moffitt Cancer Center (Tampa, FL, USA; www.moffitt.org) has discovered that two routine and easily conducted blood tests can predict which patients face a higher risk of adverse outcomes following treatment with CD19-targeted CAR T cells. The researchers identified that patients with baseline serum blood levels of c-reactive protein (CRP) at or above 4 mg/dL and ferritin levels of 400 ng/mL or higher are at the greatest risk of poor outcomes. This finding offers a chance to enhance the safety and effectiveness of this rapidly evolving category of cancer immunotherapies.

Alzheimer’s Blood Test Could Replace Spinal Taps and Brain Scans

Astudy by researchers at Washington University School of Medicine in St. Louis (WUSM, St. Louis, MO, USA; medicine.washu. edu) and Lund University (Lund, Sweden; medicin.lu.se) has demonstrated that a blood test can diagnose Alzheimer’s disease pathology as precisely as cerebrospinal fluid tests and brain scans. This is true even for patients with mild symptoms and can detect molecular signs of Alzheimer’s in the brain before symptoms appear. This groundbreaking blood test could potentially replace more costly and invasive methods like brain scans and spinal taps for identifying Alzheimer’s indications in the brain. The results of the study were published in the March issue of Blood Cancer Discovery.

Method Detects Pathogens in Blood Faster and More Accurately by Melting DNA

Researchers at UC San Diego (La Jolla, CA, USA; be.ucsd.edu) have developed a new analysis technique that offers quicker and more precise pathogen detection in blood samples compared to traditional blood cultures, which are the standard in infection diagnosis. The new method, called digital DNA melting analysis, is capable of delivering results in less than six hours. This marks a significant improvement over the typical 15 hours to several days required by culture methods, depending on the pathogen involved. This method not only outpaces blood cultures in terms of speed but also has a substantially lower risk of generating false positives compared to other emerging DNA detection technologies, such as Next Generation Sequencing. The method was demonstrated in study published on February 20 in the Journal of Molecular Diagnostics.

Cell Sorter Chip Technology to Pave Way for Immune Profiling at POC

Researchers at IMEC (Leuven, Belgium; www.imec-int.com) have developed a novel cell sorter chip technology that could bring immune monitoring to clinical practice for creating a truly personalized cancer treatment plan. This technology could allow oncologists to use a portable tool, about the size of a lunchbox, in their office or daycare center to periodically check a patient’s immune system. This marks a significant step towards developing a point-ofcare tool for immune profiling, a groundbreaking advancement in cancer therapy that aims to customize treatment plans for each patient.

Wireless Hepatitis B Test Kit Completes Screening and Data Collection in One Step

To overcome the problem of inadequate access to screening for Hepatitis B, researchers from Chulalongkorn University (Bangkok, Thailand; biochemistry.md.chula.ac.th) have developed a wireless, point-of-care test for Hepatitis B Virus that can make diagnosis simpler and faster. The kit utilizes an electrochemical biosensor based on the specific interaction between antigens and antibodies. The testing kit enables healthcare providers in smaller medical facilities or public health centers to independently conduct hepatitis B screenings, yielding results comparable to those of sophisticated machine-based tests.

Simple Blood Test Can Predict Heart Attack Risk within Six Months

Researchers at Uppsala University (Uppsala, Sweden) have developed an online tool that, when used in conjunction with standard blood test results, can help clinicians determine if a person is at an elevated risk of experiencing a heart attack within the next six months. Inter-

estingly, existing healthcare blood samples are sufficient to predict this risk. This tool is intended to boost patients’ motivation to adopt healthier lifestyles, such as adhering to preventive medication regimens or quitting smoking. The researcher’s findings were published on February 12 in Nature Cardiovascular Research.

First Affordable and Rapid Test for Beta Thalassemia

Hemex Health’s (Portland, OR, USA; www. hemexhealth.com) Gazelle Hb Variant beta thalassemia test offers an accurate and convenient solution, aiding couples in making informed reproductive decisions, ensuring proper maternal care, and facilitating early diagnosis in infants. The test is capable of identifying 19 hemoglobinopathy conditions, including both beta-thal disease and trait, and sickle cell disease and trait. The test runs on the Gazelle compact, rugged, battery-powered in vitro diagnostic device that is designed for cost-effective use by entry-level healthcare workers, even in areas with limited access, resources, or electricity.

Latest Research Advances Blood Tests for Psychiatric and Neurological Disorders

Using genetic material from human blood and lab-grown brain cells, researchers at Johns Hopkins Medicine (Baltimore, MD, USA; www. hopkinsmedicine.org) have made advances in developing a blood test to detect brain-related changes associated with postpartum depression and other psychiatric and neurological disorders. The research focused on tracing brain cell-derived messenger RNAs (mRNAs) in the bloodstream. The ultimate aim is to create a simple blood test to detect mRNA level changes related to mental disorders, potentially allowing for early detection of psychiatric emergencies like suicidal behavior. By identifying patients at risk of a psychiatric episode, intervention and prevention of adverse outcomes could be possible.

MARCH

New Malaria Test is 12 Times Faster

Researchers at Rice University (Houston, TX, USA; engineering. rice.edu) have developed a new test for diagnosing malaria that is both rapid and accurate. This POC microfluidic point-of-care (mPOC) immunoassay is designed for quantifying a malaria parasite biomarker, Plasmodium falciparum histidine-rich protein 2 (PfHRP2), in whole blood. This device provides dual

diagnostic modes to detect PfHRP2 at low and high concentrations, making it versatile for various diagnostic needs, such as identifying asymptomatic infections and predicting disease progression. The test produces results in just 15 minutes, which can be easily accessed via a smartphone app developed by the researchers. The test was detailed in a study published in Biosensors and Bioelectronics

Accurate Assay for Endocrine Diseases

Researchers from Aarhus University (Aarhus, Denmark; biomed.au.dk) have discovered a groundbreaking method for measuring levels of free cortisol directly from a blood sample. This new method is simple and quick, requiring only a few drops of blood. This contrasts sharply with current practices,

which are both cumbersome and inaccurate. The new method addresses these issues by employing a cell-based assay, which not only improves the accuracy and reliability of cortisol measurements but also reduces the high variation commonly seen in patient samples. The method was demonstrated in a study published in the journal Analytical Chemistry.

Test Strip Offers PCR-Level Accuracy in Rapid Testing

Anew technology developed by a team of biomedical engineers at UNSW Sydney (Sydney, Australia; research.unsw.edu. au) offers test strips that are as accurate as lab-based PCR tests, with the added advantage of quick, on-site disease detection. The technology allows for the detection of specific gene sequences at room temperature, using

β-Hydroxybutyrate

• Quantitative results for early diagnosis and monitoring of ketoacidosis

• Highly specific due to quantification of predominant ketone body

• Liquid-stable, ready-to-use reagents with high linearity and excellent stability

• Superior performance compared to urine strip ketone testing

DiaSys. Total Confidence in Patient Results. www.diasys-diagnostics.com

test strips that resemble the familiar RAT Covid test, potentially eliminating the need for long queues at PCR testing centers and drastically reducing costs to a few dollars per test. The test strips could be instrumental in rapidly responding to new pathogens, identifying areas with high antibiotic resistance, or in conservation efforts for endangered species. The findings were published on March 5 in Nature Communications

Tuberculosis Test to Expand Testing Access in Emerging Countries

Anew test would allow testing for TB treatment monitoring to occur outside of a BSL-3 laboratory, potentially making it easier and faster to treat TB worldwide. The new TB test — called rapid enumeration and diagnostic for tuberculosis (READ-TB) — was disclosed in the Association for Diagnostics & Laboratory Medicine’s (ADLM, Washington, DC, USA; www.myadlm.org) Clinical Chemistry journal and has been designed specifically to address the lack of access to labs that meet BSL-3 requirements. The READ-TB test isn’t just safer and easier; it could also help with TB drug research. By accurately measuring TB RNA levels, scientists can compare different TB drugs or drug combinations more effectively.

Improved Microneedle Technology Speeds Up Extraction of Sample Interstitial Fluid for Disease Diagnosis

Researchers have developed improved microneedle technology that enhances the extraction of interstitial fluid by collecting more fluid in less time. Sandia National Laboratories (Albuquerque, NM, USA; www.sandia.gov) is leading the way in microneedle research through collaboration with different partners to enhance this technology. Sandia has achieved a breakthrough in interstitial extraction, moving from using multiple needle arrays to a single microneedle technique that collects enough fluid for analysis in just about 10 minutes. Additionally, Sandia is investigating the biomarkers present in interstitial fluid to see how they correlate with blood measurements. Sandia is also working on another project to develop microneedle sensors that detect electrolytes like sodium, potassium, and calcium.

Simple Skin Biopsy Test Detects Parkinson’s and Related Neurodegenerative Diseases

Progressive neurodegenerative diseases, including Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy, and pure autonomic failure, have some similar symptoms like tremors and cognitive issues, but vary in their outcomes and do not benefit from identical treatments. A common feature among them is the accumulation of an abnormal protein in nerve fibers within the skin, known as phosphorylated α-synuclein (P-SYN). Neurologists

at Beth Israel Deaconess Medical Center (BIDMC, Boston, MA, USA; www.bidmc.org) have developed a simple skin biopsy test that can detect this abnormal form of alpha-synuclein with high positivity rates. This research demonstrates the potential of skin biopsies as a valuable diagnostic tool for identifying the pathological hallmark of Parkinson’s and related disorders. The findings were published in JAMA on March 20.

Coin-Sized Device Rapidly Isolates Blood Plasma for Quicker and More Precise Clinical Diagnoses

Researchers at Nanyang Technological University (NTU, Singapore; www.ntu.edu. sg) have developed a compact, coin-sized chip capable of extracting blood plasma directly from a sample within 30 minutes, resulting in a more convenient and user-friendly option than the current laborious centrifugation method. The chip named ExoArc, offers a one-step solution to achieve over 99.9% purity by efficiently removing blood cells and platelets. This advance promises quicker and more reliable clinical analysis of critical biomarkers.

Intra-Operative POC Device Distinguishes Between Benign and Malignant Ovarian Cysts within 15 Minutes

The need for a rapid method to differentiate between benign and malignant ovarian cysts during surgery is critical to inform management and treatment choices effectively. INEX Innovate (Singapore; www.inex.sg) has introduced the OvaCis Rapid Test, a novel intraoperative in vitro diagnostic (IVD) device. This test, with the ability to rapidly distinguish benign from malignant ovarian cysts within just 15 minutes, provides surgeons with immediate diagnostic data. This enables them to make quicker, more informed decisions and reduce unnecessary surgical procedures.

Blood Test Identifies Patients at Highest Risk of Dying from Heart Failure

Acollaborative study by researchers at the University of Oxford (Oxford, UK) and University of Glasgow (Scotland, UK) found that measuring neuropeptide Y (NPY) levels could predict the progression of heart failure, paving the way for a blood test to assist in managing heart failure treatment within the next five years. The study found that patients with the highest NPY levels had a 50% greater chance of dying from heart complications within three years of the study, compared to those with lower NPY levels. Identifying high-risk individuals early could guide medical professionals in choosing the most effective treatments, including the possibility of installing a lifesaving implantable cardioverter defibrillator (ICD). The study was published in the European Journal of Heart Failure.

Novel Smart Hydrogel Paves Way for New ‘Lollipop’ Mouth Cancer Diagnostic

Researchers from the University of Birmingham (Birmingham, UK) have developed a ‘lollipop’ diagnostic tool using innovative smart hydrogel technology that promises a quicker, more accurate, and less invasive way to diagnose mouth cancer, potentially leading to earlier detection for patients. This innovative diagnostic tool works by having patients transfer saliva into the hydrogel by sucking on the ‘lollipop.’ Subsequently, proteins indicative of the early stages of mouth cancer can be isolated by exposing the hydrogel to UV light, releasing the captured proteins for laboratory analysis. The biocompatible hydrogel concentrates and labels proteins with a fluorescent marker in just one step, making it ideal for diagnostics that aim to detect low abundance proteins from small samples.

TB Blood Test Could Detect Millions of Silent Spreaders

In a significant development, scientists have advanced towards developing a blood test capable of detecting millions of people who are unknowingly transmitting TB. In a pioneering study conducted by the University of Southampton (Southampton, UK), researchers have identified a specific group of biological markers present in high levels in individuals who are infectious. This discovery holds the promise of a simple diagnostic test capable of identifying and halting the spread of the disease, which affects an estimated 10 million people each year. The findings were published on March 21 in JCI Insight.

AI Technique Advances Colorectal Diagnostics

Computer-aided diagnosis (CAD) systems for colorectal pathology face challenges due to the high data volume and the massive resolution of images, leading to a bottleneck in deep learning (DL) approaches that extract patches from the whole slides. Now, researchers at INESC TEC (Porto, Portugal; www.inesctec.pt) and IMP Diagnostics (Porto, Portugal; www. impdiagnostics.com) have created a pioneering prototype that employs artificial intelligence (AI) for colorectal diagnosis. This prototype is a result of a technical innovation involving a new, more efficient training methodology that significantly reduces the number of images needed to train the AI model without compromising its effectiveness. The advancement not only enhances image analysis technology but also contributes to developing more efficient solutions for diagnosing colorectal cancer.

New Device Overcomes Phlebotomy Problems

Avirtually pain-free, low cost, easy-to-use, whole blood and plasma collection and dispensing system solves the problem of the

AMPLIRUN®

Take control, molecular control

Widest range of independent third-party controls, valid for any molecular testing platform

> More than 140 pathogens available

• Contain purified nucleic acid, complete microbial genome

• Precise concentration in copies/µl verified by qPCR.

• Lyophilized presentation ensures stability and reduces transport costs.

Annual Review 2024

physical pain of a traditional blood draw, making it easier, cheaper, and faster to potentially receive a diagnosis. RedDrop Dx’s (Fort Collins, CO, USA; www.reddropdx.com) innovative blood collection device, RedDrop One, aims to enhance blood collection technology and patient care practices. With its user-centric design, RedDrop One eliminates many of the drawbacks associated with traditional blood collection methods, allowing for the collection of larger blood volumes more efficiently and with significantly less discomfort for the patient.

Groundbreaking Blood Test Offers Earlier Pancreatic Cancer Diagnosis

For the first time, researchers at Metabolomycs (Long Beach, CA, USA; www.metabolomycs. com) have utilized targeted mass spectrometry to demonstrate that pancreatic cancer stems from changes in cellular metabolism that are detectable using a simple blood test. In contrast to genomic approaches that measure DNA for early detection and often struggle with false positives and negatives, mass spectrometry can measure extremely low concentrations of biochemicals in plasma with remarkable accuracy. This method could lead to more precise and earlier diagnoses of pancreatic cancer than currently possible with tumor markers or imaging techniques, potentially paving the way for more timely and appropriate therapeutic interventions.

APRIL

Blood Test Improves Sepsis Diagnosis

Researchers from Lund University (Lund, Sweden) have successfully identified distinct molecular signatures associated with the clinical signs of sepsis that could enable more accurate diagnosis and prognosis of sepsis, as well as help design targeted therapies for patients who stand to benefit the most. Through mass spectrometry, the researchers developed detailed molecular profiles, enabling them to identify protein patterns that accurately predict septic shock. This information was used to create a machine-learning model, categorizing patients into risk groups for developing septic shock, thus demonstrating the model’s potential to predict sepsis severity and associated mortality risks accurately. The research was presented at ESCMID Global 2024 (formerly ECCMID) in Barcelona, Spain.

Deep Learning Powered AI Algorithms Improve Skin Cancer Diagnostic Accuracy

Anew study led by researchers at Stanford Medicine (Stanford, CA, USA; www.med. stanford.edu) has found that artificial intelligence (AI) algorithms, which utilize deep learning, can enhance the accuracy of diagnosing skin cancers. This benefit extends to dermatologists, though the improvement is more pronounced for non-dermatologists. The researchers are now

looking to further explore the potential and challenges of integrating AI tools into healthcare, particularly focusing on how physicians’ and patients’ perceptions and attitudes towards AI could affect its adoption. The study’s findings were published on April 9 in NPJ Digital Medicine

Genetic Testing Combined with Drug Screening of Tumors Could Transform Cancer Treatment

For the first time, researchers at Florida International University (Miami, FL, USA; stempel.fiu.edu) have combined genetic testing with personalized drug screening directly on tumor samples to identify the right treatment for children with relapsed cancers, offering a timelier and effective approach. The functional precision medicine approach to target cancer combines genetic testing with a new method of testing individual drugs on tumor samples. The combined approach offers advantages over the current precision medicine processes by speeding up results and broadening treatment possibilities. According to the study results published on April 11 in Nature Medicine, this approach offered a safe, accessible, effective, and affordable for patients with no other treatment options.

Single Genetic Test to Accelerate Diagnosing Rare Developmental Disorders

Astudy by researchers from the Wellcome Sanger Institute (Cambridgeshire, UK; www.sanger.ac.uk) along with their collaborators suggests that a genetic test could be capable of replacing the existing dual-step diagnostic approach for identifying rare developmental disorders in children. The researchers devised a single-assay technique that integrates four algorithms using machine learning to examine exome sequencing data. This method could replace existing diagnostic procedures, offering quicker, more accurate detection of rare genetic diseases, and potentially leading to significant savings for healthcare systems.

Multiplex PCR Test Identifies 95% of Sepsis-Causing Pathogens

Deepull (Barcelona, Spain; www.deepull. com) has unveiled its UllCORE benchtop diagnostic system that could revolutionize life-saving clinical decision-making for sepsis patients. The system is capable of delivering 50 reportable results within an hour and covers 95% of pathogens known to cause sepsis, including resistance genes. The real-time multiplex PCR system operates by extracting total microbial DNA from an 8 mL sample of whole blood, bypassing the traditional and time-consuming blood culture process. The UllCORE assay encompasses a broad array of bacterial targets, fungi, and genes that create antibiotic resistance, enhancing the ability of clinicians to make more informed decisions faster. This rapid and sensitive technology aims to reduce the

risks associated with inappropriate antibiotic use, thereby aiding in the battle against antimicrobial resistance in hospital settings.

Innovative Platform Provides

Antibiotic Susceptibility Testing with Unprecedented Speed

Agroundbreaking diagnostic platform that delivers antibiotic susceptibility test (AST) results with unprecedented speed can become an important tool for healthcare professionals to manage bacteremia. The LifeScale AST system from Affinity Biosensors (Santa Barbara, CA, USA; www.affinitybio.com) is a state-of-the-art diagnostic platform that rapidly identifies the most effective antibiotics for treating dangerous bloodstream infections. This revolutionary system enables healthcare professionals to make well-informed treatment decisions, enhancing patient recovery, minimizing treatment costs, and promoting responsible antibiotic use.

Next Generation Instrument Screens for Hemoglobin Disorders in Newborns

Anext generation instrument dedicated to newborn hemoglobin screening offers a smooth workflow and excellent analytical capabilities. Sebia’s (Lisses, France; www.sebia. com) CAPILLARYS 3 DBS instrument is an automated, multitasking capillary electrophoresis instrument that uses 12 capillaries simultaneously for hands-free electrophoretic separation at high throughput. Designed to detect both standard (F and A) and abnormal hemoglobins (S, C, E, D, and Bart’s) in dried blood samples collected on filter paper from newborns, this instrument provides a qualitative analysis that enhances laboratory efficiency, ensures high throughput, and maintains complete traceability from the dried blood spot card to the final result, all within a cyber-secured environment.

Clinical Decision Software a Game-Changer in the Antimicrobial Resistance Battle

In a significant stride towards preventing antimicrobial resistance (AMR), a groundbreaking medical device developed by Smart Blood Analytics Swiss (Zürich, Switzerland; www. sba-swiss.com) can accurately differentiate between viral and bacterial infections, thereby assisting doctors in administering precise and effective treatment. The VIRUS vs. BACTERIA Clinical Decision Support Software utilizes just 17 routine blood parameters, biological sex, and age to effectively distinguish between viral and bacterial infections. With routine blood testing widely available globally, VIRUS vs. BACTERIA significantly enhances the ability of physicians to differentiate between viral and bacterial infections and supports the rational use of antibiotics, particularly in scenarios where traditional blood markers have limited diagnostic value.

Organ Transplant Rejection Test Could Replace Surgical Biopsies

Researchers at Yale School of Medicine (New Haven, CT, USA; www.medicine.yale.edu) have achieved a potential breakthrough in monitoring acute cellular rejection (ACR) via blood tests by focusing on T cell exosomes, which are significantly altered during ACR. Their study, published in the March issue of the American Journal of Transplantation, demonstrates that T cell exosomes not only indicate the occurrence of ACR but may also contribute to the damage in transplant rejection. The ongoing research aims to validate this biomarker in a larger cohort of heart transplant recipients and to extend the findings to lung transplant monitoring. Ultimately, this could lead to replacing invasive surgical biopsies with a simple blood test for detecting ACR, enhancing the quality of life and potentially saving more lives by facilitating timely interventions.

MAY

AI Accurately Predicts Tumor-Killing Cells

Cellular immunotherapy involves extracting immune cells from a patient’s tumor, potentially enhancing their cancer-fighting capabilities through engineering, and then expanding and reintroducing them into the body. T cells, a primary type of white blood cell or lymphocyte, circulate in the blood and monitor for virally infected or cancerous cells. Among these, T cells that infiltrate solid tumors are known as tumor-infiltrating lymphocytes, or TILs. However, not all TILs effectively recognize and attack tumor cells. To address this, scientists at Ludwig Cancer Research (New York, NY, USA; www.ludwigcancerresearch. org) have now employed artificial intelligence (AI) to create a predictive model that can identify the most effective TILs for use in cancer immunotherapy.

New Era in Automated Tuberculosis Testing

Aunique blood-based interferon-gamma release assays (IGRA) paired with an automated liquid handling platform enables accurate tuberculosis (TB) testing and streamlined lab workflows without compromising on clinical performance. Revvity, Inc. (Waltham, MA, USA; www.revvity.com) has introduced the T-SPOT.TB test for use on the Auto-Pure 2400 liquid handler from Allsheng (Hangzhou, China; www. allsheng.com). This test is an interferon-gamma release assay (IGRA) that uses the enzyme-linked immunospot (ELISPOT) technology for the detection of LTBI. This technology involves crucial steps recognized by

the World Health Organization as vital for ensuring dependable and accurate TB testing results.

Pre-Dementia Alzheimer’s Test

Ateam of researchers from Aarhus University (Aarhus, Denmark; biomed.au.dk) has identified a specific receptor found on immune cells that can bind and neutralize harmful “beta proteins”, which are closely linked with the development of Alzheimer’s disease. The study underscores the significant role that the peripheral immune system may play in defending the body against Alzheimer’s by preventing the build-up of these harmful proteins in the brain. This discovery paves the way for detecting the disease-related changes much earlier than current methodologies allow.

New Guidelines for Respiratory Viral Infection Testing

Amultidisciplinary team of clinical microbiologists and infectious disease clinicians convened by the Association for Diagnostics & Laboratory Medicine (ADLM, formerly AACC, Washington, D.C., USA; www.myadlm.org) has released a new guidance document, offering expert advice on essential aspects of clinical testing for respiratory viral infections. The guidance, endorsed by the Pan American Society for Clinical Virology, reflects the latest insights from COVID-19 and other respiratory virus research with the aim of maximizing the benefits of recent technological advances in this rapidly evolving field.

Urine Test to Revolutionize Lyme Disease Testing

Researchers at George Mason University (Fairfax, VA, USA) have developed a urine test for Lyme disease that detects the Borrelia bacteria, which causes Lyme disease. The test specifically targets molecules originating from the bacteria, ensuring high accuracy and the ability to detect the infection early. The test matches the exact amino acid sequences unique to Borrelia, enhancing its specificity. During clinical trials, this urine test demonstrated a 90% true positive rate and nearly 100% specificity. This advancement allows for the confirmation of an infection shortly after a tick bite, leading to timely treatment and helping to avoid the disease’s long-term debilitating effects.

New Blood Test Device Modeled on Leeches Diagnoses Malaria

Researchers at ETH Zurich (Zurich, Switzerland; www.ethz.ch) have developed an innovative device for taking blood samples that uses microneedles and a suction cup instead of a large needle, which could

be especially beneficial for those with needle phobia. The device operates on a principle similar to that of a leech and is less invasive than traditional arm blood draws. This device can collect more blood than the traditional finger prick, enhancing the reliability of diagnostic measurements. Additionally, its low production cost makes it feasible for use in developing countries.

DNA Origami Technique Advances Disease Diagnosis

DNA origami is a method used to create nanostructures with exceptional precision, utilizing DNA strands as the foundational building blocks. These structures, however, are inherently fragile and prone to disintegration under biological conditions, such as fluctuations in temperature or the presence of certain enzymes in living organisms. To address this vulnerability, a team of scientists from the universities of Portsmouth (Portsmouth, UK) and Leicester (Leicester, UK) has devised an innovative method to both customize and strengthen DNA origami, offering the potential to advance drug delivery and disease diagnostics. This new method is both scalable and economical, compatible with existing origami designs, and does not require redesigning the scaffold. The team demonstrated the method in a study published on May 2 in the Journal of the American Chemical Society (JACS).

Game-Changing Blood Test for Stroke Detection

Anew test combines blood-based biomarkers with a clinical score to accurately identify patients suffering from large vessel occlusion (LVO) strokes. This groundbreaking technology, developed by researchers at Brigham and Women’s Hospital (Boston MA, USA; www. brighamandwomens.org), could significantly shorten the time to treatment worldwide. This diagnostic tool shows promise for use in lowand middle-income countries, where advanced imaging might not be available, and for assessing traumatic brain injuries. Further research includes a new prospective trial to evaluate the test’s effectiveness in ambulances, alongside an interventional trial designed to accelerate stroke patient triage by bypassing conventional imaging for direct intervention.

JUNE

Test Cuts UTI Detection to 45 Minutes

Agroundbreaking test promises to revolutionize the treatment of Urinary Tract Infections (UTIs) by bringing advanced laboratory testing capabilities directly into the doctor’s office. The PA-100 AST System, developed by Sysmex Astrego AB (Uppsala, Sweden; www. sysmex-astrego.se), is a cutting-edge diagnostic tool that can detect a bacterial infection in just

15 minutes and determine the appropriate antibiotic for treatment within 45 minutes. Designed for use in doctor’s offices, the analyzer is fully automatic and requires no maintenance. Its rapid testing capability is a significant improvement over traditional methods, which can take days to culture bacteria and determine antimicrobial susceptibility.

Test Predicts Organ Transplant Outcomes

In a landmark study, an interdisciplinary research team from The Westmead Institute for Medical Research (WIMR, NSW, Australia; www.westmeadinstitute.org.au) and the University of Sydney (NSW, Australia) has identified, for the first time, common molecular biomarkers for transplant rejection across major transplanted organs, including hearts, lungs, livers, and kidneys. Their findings suggest that the molecular pathways involved in organ rejection are consistent across these different solid organs. This breakthrough is crucial as it enables the development of strategies aimed at improving the success rates of all types of organ transplants by utilizing machine learning to predict transplant outcomes with remarkable accuracy. The study was published in Nature Medicine on June 18.

Portable Device Monitors Cancer Patient Health

Anew at-home white blood cell monitor offers doctors the ability to remotely monitor their patients’ health more comprehensively. This device, which avoids blood draws, uses light to scan the skin at the top of the fingernail and employs artificial intelligence (AI) to identify critically low levels of white blood cells. Based on technology first conceived by researchers at MIT (Cambridge, MA, USA; www.web.mit. edu) in 2015, Leuko Labs (Boston, MA, USA; www.leuko.com) developed the device which has successfully enabled the detection of low white blood cell counts in hundreds of cancer patients without the need for blood withdrawal.

DNA Spit Test More Accurate at Identifying Future Prostate Cancer Risk

Asaliva-based test that individuals can perform at home has proven better at predicting the risk of developing prostate cancer than the traditional blood test. Researchers from The Institute of Cancer Research (London, UK; www.icr. ac.uk) and The Royal Marsden NHS Foundation Trust (London, UK; www.royalmarsden.nhs.uk) conducted a trial (BARCODE 1) of this innovative DNA test that screens for genetic variants associated with prostate cancer. This test showed a lower rate of false positives compared to the PSA test, identified cancer cases that the PSA test missed, and detected a higher percentage of aggressive cancers. It even identified prostate cancer cases that were overlooked by MRI scans.

New Blood Test Identifies Children with Rare Heart Condition

Hypertrophic cardiomyopathy (HCM) is a hereditary condition that leads to the thickening of the heart muscle and is the most frequent cause of sudden death among children and teenagers. There is no cure for HCM, and it can occasionally lead to sudden death in young individuals. A novel blood test now offers hope in identifying children afflicted by this potentially lethal heart condition. Researchers at University College London (London, UK) have demonstrated that this new test, which measures seven specific proteins in the blood, can effectively serve as an indicator for HCM. Additionally, it can identify four proteins that are associated with a higher risk of sudden death. This breakthrough creates the possibility of such a test being used to speed up the diagnosis and treatment of children with HCM. The results of the research were published in the journal Circulation: Genomics and Precision Medicine on June 7.

Rapid Diagnostic Test for Brain Tumors

Acollaborative team of neurosurgeons, oncologists, and pathologists at Mass General Brigham (Somerville, MA, USA; www. massgeneralbrigham.org) has developed a rapid genotyping test for patients presenting with central nervous system (CNS) lesions, which has eliminated the need for invasive surgical biopsies in seven cases, reducing the time to diagnosis from 10 days to just 2. The rapid genotyping test identifies genetic markers of various CNS tumors from cerebrospinal fluid (CSF), gathered during a lumbar procedure. This test not only speeds up the diagnosis but also avoids the need for more invasive brain biopsies in some cases. The team’s results were published in the American Society of Hematology’s Blood journal.

Low-Cost CRISPR-Based Paper Strip Test for Flu Diagnosis

Researchers from the Broad Institute of MIT and Harvard (Cambridge, MA, USA; www.broadinstitute.org) and Princeton University (Princeton, NJ, USA) have developed a low-cost paper strip test that could enable more individuals to determine the type of flu they have and receive appropriate treatment. This innovative test employs CRISPR technology to differentiate between the primary seasonal flu types, influenza A and B, and the subtypes H1N1 and H3N2. It can also identify strains resistant to antiviral treatments and could potentially extend to detecting swine and avian flu strains, including H5N1, which currently affects cattle. This could enhance both outbreak response and clinical care by making accurate, affordable, and rapid testing accessible in doctors’ offices and laboratories across the world. The research was published in The Journal of Molecular Diagnostics on June 18, 2024.

JULY

Sepsis Testing Reduced from Days to Hours

The ultra-Rapid Antimicrobial Susceptibility Testing (uRAST) developed by researchers from the Department of Electrical and Computer Engineering at Seoul National University (Seoul, Korea; www.eng.snu.ac.kr), in collaboration with QuantaMatrix Inc. (Seoul, Korea; www.quantamatrix.com), is the world’s first to bypass the lengthy blood culture phase, allowing for the completion of all necessary tests for an effective antibiotic regimen within a single day. The ultra-rapid antimicrobial susceptibility testing (AST) method that bypasses the need for traditional blood culture has demonstrated the potential to reduce the turnaround time of reporting drug susceptibility profiles by more than 40–60 hours compared with hospital AST workflows.

Rapid Method for Determining Virus Infectivity Can Revolutionize Response to Future Pandemics

Anew groundbreaking assay can screen viruses against virucidal antivirals in minutes, enabling quick determination of the effectiveness of antiviral measures, such as disinfectants. This innovative technique, devised by researchers at the University of Birmingham’s School of Chemistry (Birmingham, UK), employs a dye that can ordinarily penetrate viruses through pores in the capsid (protein shell) surrounding its genetic material (DNA or RNA). When the dye binds to the viral DNA or RNA, it emits a fluorescent signal. The resulting assay, named FAIRY (Fluorescence Assay for vIRal IntegritY), quickly indicates whether a virus is intact and likely infectious, or damaged and non-infectious. The technique was detailed in a study published in ACS Biomacromolecules on July 23.

POC Detection of Stroke within Minutes

Agroundbreaking diagnostic test can identify a large vessel occlusion (LVO) stroke within 15 minutes, expediting patient transfer to specialized care and saves more than 1 hour 30 minutes over the current clinical pathway. The innovative LVOne test from UpFront Diagnostics (Cambridge, UK; www. upfrontdiagnostics.com ) employs a combination of blood-based biomarkers and clinical scoring to accurately detect patients undergoing

an LVO stroke. A clinical study has confirmed the efficacy of UpFront’s specific blood biomarkers GFAP and D-dimer, achieving 90% accuracy in identifying LVO strokes.

Protein Signatures in Blood Can Predict Risk of Over 60 Diseases

New research carried out as part of an international partnership involving Queen Mary University of London (London, UK; qmul.ac.uk) highlights the broader potential of protein measurements from a small blood sample to predict a variety of diseases. This project represents the largest proteomic study to date, analyzing around 3,000 plasma proteins from over 40,000 randomly selected UK Biobank participants. The researchers applied sophisticated analytical techniques to identify a specific ‘signature’ of 5 to 20 key proteins for predicting

each disease and discovered that these protein ‘signatures’ can predict the onset of 67 different diseases. The findings were published on July 22 in Nature Medicine.

ADLM 2024 Highlights Innovations Shaping the Future of Clinical Diagnostics

The Association for Diagnostics & Laboratory Medicine (ADLM, Washington, DC, USA; www.myadlm.org) hosted the ADLM 2024 Clinical Lab Expo (formerly AACC Annual Scientific Meeting & Clinical Lab Expo) in Chicago on July 28–August 1, featuring latest advances in diagnostic research and technology and accentuating the essential role laboratory medicine plays in healthcare. This year, 18,000 laboratory medicine professionals registered for ADLM 2024, a 6% increase in at-

Annual Review 2024

tendance over the last ADLM Annual Meeting in Chicago in 2022. The ADLM 2024 Clinical Lab Expo boasted nearly 900 exhibitors and covered over 270,000 sq. ft. (25,000 sq. m.) of net exhibition space. The exhibition featured cutting-edge tests from all laboratory medicine disciplines, including artificial intelligence, molecular diagnostics, automation, point-of care testing, mass spectrometry, and mobile health.

Rapid Blood Test for Hypothyroidism

Genalyte (San Diego, CA, USA; www.genalyte.com) has received U.S. Food and Drug Administration (FDA) approval for its groundbreaking Thyroid Stimulating Hormone (TSH) immunoassay, the first of its kind to be cleared for use on a silicon chip-based device. The Maverick Diagnostic System (MDS) incorporates silicon chip-based photonic ring resonator technology, enabling the execution of multiple rapid tests simultaneously from a small sample of whole blood or serum. This system is also connected to the cloud, facilitating the retrieval of assay protocols and enabling clinical oversight. Genalyte’s innovation effectively minimizes the traditional bulky lab machinery to 3% of its original size while still delivering lab-quality results.

Blood Test Predicts Alzheimer’s with Over 90% Accuracy

Acommercially available blood test has demonstrated approximately 90% reliability in primary care settings, representing a major development for individuals seeking assistance for memory loss and potential Alzheimer’s. Research on this innovative blood testing method, which evaluates levels of Plasma Phospho-Tau217, commenced in 2019 with studies showing that the blood test can detect Alzheimer’s-related changes even before symptoms appear and monitor the disease’s progression. Earlier this year, results indicated that this blood test is as reliable as, and sometimes better than, cerebrospinal fluid tests for diagnosing the disease. The latest study conducted at Lund University (Lund, Sweden) is the first to evaluate the test’s reliability in routine healthcare settings, including both primary and specialist healthcare. The study was published in JAMA on July 28.

Screening Tool Detects Multiple Health Conditions from Single Blood Drop

Despite its established role in chemistry and industry, infrared spectroscopy has yet to become a standard tool in medical diagnostics. In an effort to tackle this issue, a team of scientists from the BIRD group at Ludwig Maximilian University of Munich (LMU, Munich, Germany; physik.lmu.de) has developed a diagnostic tool employing infrared light and machine learning to identify multiple health conditions in just one measurement at the population level. Traditionally, different tests are required for each condition, but this new method identifies

multiple health issues simultaneously, not just one at a time. The system not only identifies healthy people but also detects complex conditions involving multiple diseases and can predict the onset of metabolic syndrome years before symptoms manifest, offering a chance for early intervention. The tool was detailed in a study published in Cell Reports Medicine on July 16.

Simple Blood Test Identifies People with Higher Risk of Stroke

Researchers at Uppsala University (Uppsala, Sweden) have shown that a simple blood test reflecting brain health can determine which individuals are at increased stroke risk. The researchers studied the neurofilament protein, which releases from the brain under stress or low oxygen conditions, in blood samples from over 3,000 individuals with atrial fibrillation. They monitored these individuals for an average of 18 months. Those with the highest levels of neurofilament in their blood were found to face the highest stroke risk. These findings were published online on July 24 in the journal Circulation. This breakthrough could lead to more personalized treatment for patients with atrial fibrillation.

AUGUST

Magnetic

Microneedle Array Robots

to Revolutionize

Tissue Slicing and Cultivation

Ateam from Nanjing Drum Tower Hospital (Nanjing, China; www.njglyy.com) has pioneered an innovative tissue slicing and cultivation method that promises to transform how primary tissues are managed in medical settings. Their groundbreaking method incorporates a controllable histotomy technique using hierarchical magnetic microneedle array robots. This innovation not only enhances tissue analysis capabilities but also paves the way for personalized medicine and the development of more effective therapies. As this technology evolves, it is anticipated to significantly impact biomedical research and clinical practices.

Blood-Based Diagnosis Detects Prenatal Exposure to Birth Disorders

Researchers are employing sophisticated technology and artificial intelligence (AI) to improve the diagnosis of rare diseases and prenatal exposure-related birth abnormalities, as detailed in two studies. The technology, known as EpiSign, utilizes AI to analyze the epigenome—each individual’s unique chemical code that overlays their DNA and regulates gene activity. The first study, conducted by the team at London Health Sciences Centre (LHSC, London, ON, Canada; www.lawsonresearch. ca) that developed EpiSign, demonstrated its efficacy in identifying a group of birth disorders known as recurrent constellation of embryonic

malformations (RCEMs). In the second study, the same research team applied EpiSign to identify a reliable biomarker for fetal valproate syndrome for the first time.

AI Improves Lung Cancer Diagnosis

Ateam of researchers at University of Cologne (Cologne, Germany) has developed an AI-driven digital pathology platform that can revolutionize the analysis of lung cancer tissues. This platform utilizes newly developed algorithms to perform fully automated examination of digitized lung cancer tissue sections, offering faster and more precise analyses than traditional methods. The platform is founded on the most extensive and high-quality dataset available, enabling it to process H&E-stained whole-slide images (WSIs) of both resection and biopsy specimens from non-small cell lung cancer (NSCLC) patients. It can accurately segment all relevant tumor and benign tissue classes at the pixel level. The team’s findings were published online in Cell Reports Medicine on August 22.

Earlier Detection of Pancreatic Cancer

Immunovia AB (Lund, Sweden; www. immunovia.com) has reported enhanced outcomes for its next-generation test aimed at detecting early-stage pancreatic ductal adenocarcinoma (PDAC) in high-risk individuals. In April 2024, the company shared positive outcomes from the preliminary modeldevelopment study of its innovative pancreatic cancer detection test. The test’s performance was refined through the inclusion of additional samples, which provided more comprehensive and specific clinical data, and the application of advanced statistical modeling techniques. These improvements have significantly increased the test’s accuracy, boosting the sensitivity of this next-generation test to 85% and its specificity to 98% for detecting stage 1 and 2 PDAC.

Breakthrough Platelet Test

Detects Previously Unmeasured Cardiovascular Risks

Until now, assessing platelet reactivity in patients has been challenging due to inconsistencies in the conventional test, platelet aggregometry, which often shows varied results across different laboratories. To overcome this issue, researchers at NYU Grossman School of Medicine (New York, NY, USA; www.med. nyu.edu) have now accurately identified patients with hyperreactive platelets and conducted a study revealing significant genetic variations among those with hyperreactive platelets compared to others. Using bioinformatics, they developed a new metric called the Platelet Reactivity ExpresSion Score (PRESS), which effectively identifies those at risk of heart attacks and spots those who might not yet know their risk. The research was published online on August 20 in Nature Communications

Saliva Test More Accurately Indicates Severity of Recurrent Respiratory Infections in Children

New research reveals that saliva testing might offer a more accurate reflection of the severity of recurrent respiratory infections in children compared to traditional blood tests. If saliva contains too few broadly protective antibodies, there is a higher likelihood of pneumonia episodes for the children. The collaborative study by researchers at Radboudumc Amalia Children’s Hospital (Nijmegen, Netherlands; www.radboudumc.nl) and UMC Utrecht Wilhelmina Children’s Hospital (Utrecht, Netherlands; www.hetwkz.nl) involving 100 children with recurrent respiratory infections found that saliva tests are better indicators of disease severity than blood tests. The study demonstrated no significant correlation between blood antibodies and the extent of infection.

Mouthwash-Based Test Predicts Head and Neck Cancer Recurrence

Anew test using a simple mouthwash to detect biomarkers shows promise in predicting disease recurrence in patients with head and neck cancer. A previous study by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine (Miami, FL, USA; www.umiamihealth.org) explored how biomarkers in oral rinses could indicate a person’s risk of developing oral or oropharyngeal tumors, which are among the most common head and neck cancers. They identified two crucial biomarkers: CD44, a molecule linked to tumor initiation, and total protein levels. In this new study, the researchers, along with their collaborators, examined whether levels of these biomarkers could predict recurrence in patients already diagnosed with the disease. Laboratory assays showed a correlation between the levels of these biomarkers and subsequent disease recurrence. The findings were published on August 15 in JAMA Otolaryngology–Head & Neck Surgery.

POC Saliva Testing Device Predicts Heart Failure in 15 Minutes

Researchers at Colorado State University (Fort Collins, CO, USA; engr.colostate. edu/cbe) have developed a point-of-care electrochemical biosensor that works similarly to lateral flow tests like those used for COVID-19 but is designed for heart failure detection. This biosensor can analyze two heart failure biomarkers from a drop of saliva in about 15 minutes. Dubbed the electrochemical capillary-driven immunoassay (eCaDI), this device integrates innovations from their previous work—a microfluidic saliva device and a biosensor that detects biomarker proteins Galectin-3 and S100A7. In trials, the device was tested with standardized human saliva

spiked with biomarker levels indicative of heart failure, where it successfully detected the concentrations of Galectin-3 and S100A7.

Ultra-Fast Test Screens for All Types of Cancer with Simple Blood Draw

Oncosure (Pompano Beach, FL, USA; www. oncosure.info) has launched its innovative Rapid Cancer Screening Test, democratizing access to early cancer detection. This test, requiring only a single blood draw, is capable of screening for all cancer types, thereby providing reassurance to individuals. Oncosure’s cutting-edge screening technology employs rapid in situ hybridization and DNA fluorescent probes to deliver a comprehensive and accurate cancer screening. The technology combines a rapid SITU hybridization platform, DNA fluorescent probes for ploidy detection, and cost-effective density gradient and low sequential centrifugation methods to provide thorough screening for aneuploidy across all chromosomes.

SEPTEMBER

Parkinson’s Detected 20 Years Prior to Symptoms

Researchers at Tel Aviv University (Tel Aviv, Israel), in collaboration with three major Israeli medical centers, have developed a novel method for detecting protein aggregation in cells. This new approach utilizes super-resolution microscopy combined with computational analysis to precisely map the molecules and structure of protein aggregates. This technology could allow for diagnosis up to 20 years before the onset of motor symptoms, paving the way for early intervention or prevention of the currently incurable disease. The study detailing the technology was published on September 3 in Frontiers in Molecular Neuroscience.

Earlier Detection of Neurological Disorders

Researchers at University of Central Florida (Orlando, FL, USA) have developed an integrated optical sensor capable that can detect dopamine directly from unprocessed blood samples, offering a cost-effective and efficient method for screening various neurological conditions and cancers, thus potentially enhancing patient outcomes. In contrast to traditional biosensors that depend on biological components such as antibodies or enzymes, this novel sensor employs a specially crafted aptamer, a synthetic DNA strand, that targets dopamine specifically. This design not only reduces costs and extends the shelf life of the sensor but also allows for the direct detection of dopamine in unprocessed blood, eliminating the need for sample preparation. This innovation is particularly valuable in resource-limited settings, simplifying the diagnostic process and potentially allowing for the

detection of other conditions using similar technology. The sensor was demonstrated in a study published on September 4 in Science Advances.

Easy-To-Use Point-Of-Care Testing Device Accurately Measures Cortisol Levels in Blood

Researchers at Xi’an Jiaotong-Liverpool University (XJTLU, Suzhou, China) have developed an innovative cortisol detector—a key stress biomarker in the blood. Traditional cortisol sensors use reference electrodes with a silver layer that tends to oxidize and destabilize during electrochemical measurements. In the new study published in the journal Talanta, the researchers introduced iridium oxide nanoparticles to coat the silver layer, significantly enhancing the stability, sensitivity, and reproducibility of cortisol measurements in point-of-care settings. This is the first application of iridium oxide in this manner. The resulting device is simple and affordable, capable of detecting cortisol levels at concentrations 3,000 times lower than the typical cortisol range found in blood, making it highly suitable for commercial use.

First Ever Molecular Diagnostic Tool Could Enable Early Diagnosis of Inflammatory Diseases in Children

Anew cell-free RNA-based test could become the first molecular diagnostic tool to help clinicians detect these inflammatory conditions in children at an early stage. Cell-free RNA, which is released into the bloodstream through cell death or active secretion, has been harnessed by a research collaboration led by Cornell University (Ithaca, NY, USA; www.bme.cornell.edu). The team developed machine learning models that utilize these molecular RNA fragments to diagnose complex pediatric inflammatory conditions. This diagnostic tool can accurately distinguish between Kawasaki disease, MIS-C, viral infections, or bacterial infections, while also monitoring the patient’s organ health. The research was published in the journal PNAS on September 6.

Blood Test Predicts Risk for Developing COPD

Researchers have developed a preclinical blood test to identify adults most likely to develop severe respiratory conditions, including COPD. The blood test was developed by a scientific team supported by the National Institutes of Health (NIH) and comprising investigators from Northwestern University Feinberg School of Medicine (Chicago, IL, USA; www. feinberg.northwestern.edu) and University of California, Davis Medical Center (Sacramento, CA, USA; www.health.ucdavis.edu). The test analyzes 32 proteins that scientists identified as accurate predictors of an adult’s increased likelihood of requiring medical care for or dying from severe respiratory illness. The findings

were published in the American Journal of Respiratory and Critical Care Medicine

New Technology Holistically Images Deep Living Tissue for First Time

Anew device that uses light to non-destructively image tissue could revolutionize cartilage and tissue transplant treatments, laying the groundwork for osteoarthritis therapy. Developed through collaborative research that included investigators from King’s College London (London, UK), this new device is the first of its kind to reveal the molecular structure of deep tissue without relying on limiting fluorescent labels. This readily available machine could enhance the use of tissue engineering in medicine and halve the costs of tissue production in the lab. The innovative technology was detailed in a study published on September 9 in Nature Communications.

Newly Discovered Blood Group System to Help Identify and Treat Rare Patients

The AnWj blood group antigen, a surface marker discovered in 1972, has remained a mystery regarding its genetic origin—until now. Researchers have uncovered the genetic background of the AnWj antigen, enabling the identification and treatment of rare patients who lack this blood group. The research, led by investigators from the University of Bristol (Bristol, UK), has identified a new blood group system, MAL, the 47th known system, as the home of the AnWj antigen. This discovery paves the way for the development of new genotyping tests to detect individuals with the inherited AnWj-negative phenotype, reducing the risk of complications from blood transfusions. The research was published in Blood, the journal of the American Society of Hematology.

Light-Induced Immunoassay Selectively Detects Coronavirus Spike Proteins In 5 Minutes

Scientists at Osaka Metropolitan Univerity’s Research Institute for Lightinduced Acceleration System (RILACS, www.p.s.osakafu-u.ac.jp) have developed a light-induced immunoassay for virus detection. By applying laser irradiation for less than a minute, they used a nanoparticleimprinted plasmonic substrate with nanobowl structures (each 500 nm in diameter) coated with antibodies for the spike proteins of the novel coronavirus. A low-power 5-milliwatt laser, similar to commercial laser pointers, was able to form bubbles on the biochip that attracted virus-mimicking nanoparticles, speeding up the selective detection of these particles. The entire procedure—from coating the substrate to detecting the virus—

can be completed in under 5 minutes. The findings were published in the journal npj Biosensing.

OCTOBER

New Technology Uses DNA Barcodes to Map Out Diverse Protein Interactions in Cells

Researchers from NUS Institute for Health Innovation & Technology (iHealthtech, Singapore; www.ihealthtech.nus.edu.sg) have developed a novel technology called TETRIS to map out diverse protein interactions in cells using DNA barcodes. This innovative approach allows the identification and quantification of multiple interacting partners in large protein assemblies. By cap turing the complex hierarchy of protein inter actions within tumor cells, TETRIS uncovers the molecular mechanisms driving disease progression. This leads to more accurate diagnostics, enabling the sub-typing of can cers and identifying aggressive forms of the disease within hours, a capability previously unavailable.

Platform Measures Over 100 Alzheimer’s Biomarkers

Current diagnostic methods for Alzhei mer’s are not ideal—they are time-con suming, resource-intensive, and can be bur densome for patients who must undergo repeated invasive procedures. Now, scientists at University of Pittsburgh (Pittsburgh, PA, USA: www.upmc.com) have independently validated a new blood test platform capable of measuring over 100 biomarkers related to Alzheimer’s disease. This platform could improve clinicians’ ability to capture the com plex pathology of Alzheimer’s and streamline early diagnosis. The research was published on October 10 in Molecular Neurodegener ation.

Rapid POC Sepsis Test

Based on New Biomarker

Pancreatic Stone Protein (PSP) has emerged as a promising biomarker for the early de tection of sepsis, identifying the condition 2448 hours earlier than current methods. Abionic (Epalinges, Switzerland; www.abionic.com has developed the IVD CAPSULE PSP test, which offers rapid, accurate, and easy-to-use results in critical care settings by measuring PSP levels. The IVD CAPSULE PSP operates exclusively on Abionic’s abioSCOPE platform, a near-patient rapid diagnostic system that integrates smoothly into clinical workflows. It provides lab-quality results from a drop of blood within minutes, delivering valuable insights and actionable information directly at the point of care.

Simple Blood Draw Helps Diagnose Lung Cancer 10 Times Faster

Researchers at University of Michigan (Ann Arbor, MI, USA; che.engin.umich.edu) have developed a microchip capable of capturing exosomes from blood plasma to detect lung cancer. This new diagnostic method, which uses a simple blood draw, is 10 times faster and 14 times more sensitive than previous approaches, according to the research team. The microfluidic chips, called CDEXO chips (Circular Dichroism detection of EXOsomes), could also potentially distinguish specific lung cancer mutations, aiding doctors in tailoring treatments to target the most prevalent mutations as they evolve.

Precision Medicine Blood Test Predicts Heart Disease Before It Occurs

Aprecision medicine blood test could predict heart disease before it happens and provide decision support for prophylactic therapies. AMPEL BioSolutions (Charlottesville, VA, USA; www.ampelbiosolutions.com) has published a paper in the peer-reviewed journal Cell iScience that validates and expands upon the inflammatory and immune system abnormalities in the blood of individuals predisposed to heart disease, which the company first identified two years ago. By analyzing genes expressed in single cells isolated from atherosclerotic coronary artery plaques, the study revealed biomarkers that can be measured using AMPEL’s CardioGENE blood test. This innovative approach, which connects genetic predisposition to real-time molecular pathways targeted by specific drugs, has the potential to transform healthcare by enabling physicians to assess cardiovascular disease risk and select appropriate treatments.

Cheap, Paper-Based Testing Platform Could Transform Diagnostics

Researchers have developed a new diagnostic test system that merges a field-effect transistor (FET), with a cost-effective, paper-based diagnostic test. When paired with machine learning, this system evolves into a novel biosensor that could potentially revolutionize at-home testing and diagnostics. Developed jointly by researchers at the University of Chicago Pritzker School of Molecular Engineering (PME, Chicago, Il, USA; www. pme.uchicago.edu) and UCLA Samueli School of Engineering (Los Angeles, CA, USA; www. samueli.ucla.edu), the new kind of testing system integrates an FET with a paper-based analytical cartridge, similar to the technology used in at-home pregnancy and COVID tests. This combination harnesses the high sensitivity of FETs along with the low-cost benefits of paper-based cartridges.

Chip-Based Blood Test Accurately Diagnoses Heart Attack in Minutes

Researchers at Johns Hopkins University (Baltimore, MD, USA; me.jhu.edu) have developed a new blood test that can diagnose a heart attack in minutes rather than hours, and it has the potential to serve as a tool for first responders and individuals at home. The stand-alone blood test created by the team yields results in just five to seven minutes. They claim it is also more accurate and cost-effective than current methods. While primarily intended for diagnosing heart attacks, the researchers believe the tool could also be modified to detect cancer and infectious diseases. Although initially designed for rapid diagnostic use in a clinical setting, the test could be adapted into a hand-held device for use by first responders

in the field or even for personal use at home. The team’s work was published in Advanced Science on October 15.

Point-Of-Care Paper-Based Test Could Diagnose Cancer at Bedside

Atwo-year study being conducted by researchers at UCLA Health (Los Angeles, CA, USA; www.uclahealth.org) aims to create a new test that can identify the spread of cancer to the central nervous system on the same day as the patient’s visit. The new test would facilitate same-day detection of leptomeningeal disease (LMD) and allow doctors to monitor the effectiveness of treatments like chemotherapy in real time. The research team is working on a diagnostic kit that combines sample processing with a specialized paper-assay test, akin to those utilized in at-home COVID and pregnancy tests. Their objective is to enable doctors to draw cerebrospinal fluid (CSF) from the patient and, after processing, apply it to the paper test at the care site. Ideally, the test would not only confirm the presence of cancer cells in the CSF that same day but also provide doctors with a measure of the concentration of those cancer cells.

Maternal Blood Test Identifies Congenital Heart Diseases in Fetus

Each year, around 1,000 children are born with a single ventricle heart defect (SVHD), a condition where one of the heart’s lower chambers is underdeveloped, too small, or missing a valve. Researchers at Nationwide Children’s Hospital (Columbus, OH, USA; www.nationwidechildrens.org) have discovered a potential biomarker that could detect the presence of SVHD in a fetus through a maternal blood test. This test analyzes elevated levels of cell-free microRNAs (miRNAs) in the blood of mothers carrying a fetus with single ventricle heart disease. These cell-free miRNAs could eventually serve as noninvasive biomarkers for earlier prenatal detection of single ventricle heart diseases. The findings were published on October 2 in Circulation Research.

Non-Invasive Biosensor Facilitates Early Kidney Disease Detection

Symmetric dimethylarginine (SDMA), a byproduct of protein metabolism, has emerged as a more reliable marker of kidney health. Now, a new biosensor utilizing affinity peptides has been developed to accurately measure SDMA levels in urine, providing a practical and cost-effective solution for early diagnosis and monitoring. The biosensor created by researchers at Chung Ang University (Seoul, Republic of Korea; www.neweng.cau. ac.kr) detects SDMA levels in urine, offering a non-invasive alternative to blood tests, which allows for earlier detection and management of kidney disease. The work was published online

on October 22 in the journal Biosensors and Bioelectronics.

NOVEMBER

Emerging Multi-Cancer Tests Enable Earlier Detection, Higher Survival Rates

Powered by machine learning (ML), newly-developed non-invasive Multi-Cancer Early Detection (MCED) tests can revolutionize cancer diagnostics and treatment by offering much earlier screening for multiple cancer types, all from a single blood or urine sample. One such test is the novel Enlighten MCED test from Proteotype Diagnostics (Cambridge, UK; www.proteotype.com) that offers a revolutionary approach to detecting early-stage cancers by focusing on the body’s response to tumor development. Similarly, scientists from the University of Southampton (Southampton, UK; www.southampton.ac.uk) have been awarded GBP 2.5 million to continue their work on a blood-based, multi-cancer diagnostic test, called miONCO. In addition, the Venient Sx MCED test developed by Kience Inc. (Wilmington, DE, USA; www.kience. com) is based on a blood and urine sample and promises to provide early and accurate screening for up to 42 different types of solid tumors and 5 hematological malignancies (even in the early stages), before the first symptoms and signs appear.

Cutting-Edge Diagnostic Tool Rapidly Identifies Emerging SARS-CoV-2 Variants

Researchers from Kumamoto University (Kumamoto, Japan; www.kumamoto-u. ac.jp) have made a significant advancement in the battle against COVID-19 by developing an innovative diagnostic tool that can quickly identify emerging variants of the SARS-CoV-2 virus. This new system combines advanced DNA detection technology with sophisticated computational algorithms to provide a faster and more affordable method for monitoring viral mutations, a crucial tool for managing future pandemics. The successful development of the diagnostic tool, Intelli-OVI, holds the potential to make a significant contribution to global pandemic preparedness. The research team envisions that this technology could be applied to other rapidly evolving viruses, offering an essential tool for early detection and containment strategies.

AI Tool Detects Cancerous Brain Tumor During Surgery in 10 Seconds

An artificial intelligence (AI)-based diagnostic system has been developed to detect cancerous tissue that might otherwise go unnoticed during brain tumor surgery. This technology

allows neurosurgeons to remove the cancerous tissue while the patient is still under anesthesia or treat it afterward with targeted therapies. In a new study, led by UC San Francisco (San Francisco, CA, USA) and University of Michigan (Ann Arbor, MI, USA), researchers demonstrated how an AI-powered diagnostic tool, called FastGlioma, aids neurosurgeons in identifying hidden cancer that has spread nearby. This technique holds the potential to delay the recurrence of high-grade tumors and may even prevent recurrence in lower-grade tumors. The study was published in Nature on November 13.

Smartphone Technology

Noninvasively Measures Blood Hemoglobin Levels

HemaChrome LLC (West Lafayette, IN, USA; www.hemachrome.co) has developed a smartphone-based solution that utilizes algorithms to instantly and noninvasively assess blood hemoglobin levels. Developed in collaboration with Purdue University, this machine learning-powered technology transforms a smartphone or computer camera into a hyperspectral imager by using spectroscopy and computational algorithms. The system enables users to quantify and evaluate blood hemoglobin content from a digital image of the inner eyelid, making it possible for clinicians to perform point-of-care, home-based, and remote diagnostics at a fraction of the cost of traditional methods.

Nanorobotic Hand Made of DNA Grabs Viruses for Detection or Inhibition

Researchers at the University of Illinois Urbana-Champaign (Champaign, IL, USA; bioengineering.illinois.edu) have developed a miniature, four-fingered “hand” from a single piece of DNA, designed to detect the virus responsible for COVID-19 with high sensitivity, and even prevent viral particles from entering cells to cause infection. Known as the NanoGripper, this nanorobotic hand can be customized to interact with other viruses or identify cell surface markers, potentially enabling targeted drug delivery, such as for cancer treatments. The NanoGripper’s base can attach to surfaces or other complexes, making it suitable for biomedical applications, such as sensing or drug delivery.

DECEMBER

New Hands-Free Rapid Test Detects Bacteria in Fluids

Bacteriophages, the most abundant form of life on Earth, are specialized to target and destroy specific types of bacteria. Their natural ability to fight bacteria has long been

harnessed to treat infections. Now, researchers at McMaster University (Hamilton, ON, Canada; eng.mcmaster.ca) have developed a novel test that uses harmless bacteriophages to detect disease-causing bacteria in fluids. The test utilizes bacteriophages embedded in a gel to detect bacteria in fluid samples, including urine, even at low concentrations. This test enables even untrained users to identify bacterial contamination in liquids using a biogel that changes color when exposed to bacteria like E. coli, listeria, and other common pathogens.

Microfluidic Chip-Based Device Measures Viral Immunity

People who have previously been infected or vaccinated against the flu may have some level of protection, but how well their immune system “remembers” the previous strain and reacts to the new one can vary. Currently, there is no reliable way to measure this immune “memory.” Now, new research is working to solve this issue with a device designed to assess immune memory in the blood. In a project funded by the NIH, researchers from the University of California, Davis (Da vis, CA, USA; www.ucdavis.edu) and Johns Hopkins Bloomberg School of Public Health (Baltimore, MD, USA; www.jhsph.edu) have developed a prototype device that measures memory B-cells by testing how well they can adhere to a surface while recognizing the virus under shear flow. The aim is to provide public health labs with a tool to measure immunity to new flu variants in populations, aiding in public health decision-making.

New Saliva Test Rapidly Identifies Paracetamol Overdose

Paracetamol is the most widely used medi cation worldwide. But quick and accurate paracetamol quantification is critical in guiding overdose treatment. Existing methods typically involve invasive sampling and lengthy processing times. Now, a research team led by the Univer sity of Liverpool (Liverpool, UK) has introduced a groundbreaking technique that allows for the rapid detection of paracetamol levels from saliva. In a study published in the journal cine, the team demonstrated the clinical validity of a novel Mass Spectrometry-based technique that tests a small drop of saliva on paper for parac etamol levels. This technique, called Paper-Arrow Mass Spectrometry (PA-MS), is patent-pending and was found to offer superior analytical perfor mance with reduced time, resources, and clinical involvement compared to traditional methods.

developed a novel urine test for the early detection of lung cancer. This test, the first of its kind, identifies ‘zombie’ cells, which may signal the initial stages of the disease. This test offers the possibility of identifying lung cancer months or even years before symptoms appear. The goal is that early detection through this simple urine test could lead to earlier treatment interventions, improving patient outcomes and survival rates. In some cases, this early detection could lead to cures without the need for surgery. The test could also offer a more affordable alternative to scans, which are currently used to detect lung cancer earlier.

World-First Urine Test Uses ‘Zombie’ Cell Proteins for Early Lung Cancer Detection

Researchers at the University of Cambridge (Cambridge, UK; ceb.cam.ac.uk) have

Industry News

TOP BUSINESS NEWS OF 2024

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Roche (Basel, Switzerland; www.roche.com) has entered into a definitive agreement to acquire specific parts of the LumiraDx group related to LumiraDx’s (London, UK; www.lumiradx.com) state-of-theart Point of Care technology. This acquisition is in line with Roche’s strategic goal of fostering patient-centered healthcare through innovative point-of-care solutions that cover an extensive range of healthcare settings. The terms of the agreement stipulate that Roche will make an initial payment of USD 295 million, with potential additional payments of up to USD 55 million to support the Point of Care technology platform business until the acquisition is completed.

Sysmex Corporation (Kobe, Japan; www.sysmex.co.jp) has entered into a strategic alliance agreement with CellaVision (Lund, Sweden; www.cellavision.com) to advance hematology solutions. This collaboration aims to expand Sysmex’s product range, including the development of cutting-edge cell morphology analyzers. The partnership between Sysmex and CellaVision has spanned 20 years, focusing on hematology, which involves the analysis of blood cells such as red and white blood cells in terms of their count, types, and sizes. The renewed partnership between the two companies aims to enhance their product offerings, particularly in next-generation cell morphology analyzers. They have agreed to extend their collaborative efforts to advance hematology solutions and maintain their agreement until 2038.

Beckman Coulter Diagnostics (Brea, CA, USA; www. beckmancoulter.com) and Fujirebio (Tokyo, Japan; www.fujirebio.com) have expanded their partnership focused on development, manufacturing and clinical adoption of neurodegenerative disease assays. Both the companies had entered into a collaboration agreement in 2023 to target new biomarkers in line with the recently approved monoclonal antibodybased Alzheimer’s disease therapeutics. The companies have now extended this research program and further refined the target analytes, including a pTau217 plasma assay being developed by Beckman Coulter and a Beta Amyloid 1-42 plasma assay under development by Fujirebio.

Thermo Fisher Scientific (Waltham, MA USA; www.thermofisher.com) has entered into a strategic distribution agreement with BioTechne Corporation (Minneapolis, MN, USA; www.bio-techne.com), resulting in a significant collaboration between two industry leaders in scientific research, diagnostics, and biotechnology. As per the agreement, Thermo Fisher will distribute Bio-Techne’s wide range of products, including antibodies, proteins, immunoassay kits, reagents and enzymes to laboratories and research institutions across Europe through the European arm of its Fisher Scientific Channel.

Roche (Basel, Switzerland; www.roche.com) and Hitachi HighTech (Tokyo, Japan; www.hitachi-hightech.com) have renewed their collaboration agreement, committing to a further 10 years of partnership. The collaboration between the two companies has led to significant advancements, setting new standards for in-vitro diagnostic solutions. The extended partnership underscores Roche and Hitachi High-Tech’s joint commitment to pushing the boundaries of technology, improving laboratory efficiencies, supporting medical professionals in their diagnostic decisions, and ensuring that individuals worldwide can access the fast, dependable diagnostics necessary for sustaining longer, healthier lives.

Sysmex Corporation (Kobe, Japan; www.sysmex.co.jp) has expanded its strategic alliance agreement with QIAGEN N.V. (Venlo, The Netherlands; www.qiagen.com) to deepen their cooperation in genetic testing, encompassing areas such as research and development, manufacturing, clinical development, and sales-marketing. Since their initial alliance in 2013 and their decision to forge a strategic partnership for companion diagnostics in 2021, Sysmex and QIAGEN have seen considerable collaborative success. Under the new terms, Sysmex will integrate QIAGEN’s assays into the clinical trials it conducts for pharmaceutical companies and research institutions across its global network of laboratories, enhancing QIAGEN’s global service capabilities.

QIAGEN N.V. (Venlo, the Netherlands; www.qiagen.com) has entered into a collaboration with Eli Lilly and Company (Indianapolis, IN, USA; www.lilly.com) to support the development of a QIAstat-Dx in-vitro diagnostic (IVD) to detect APOE genotypes. The QIAstat-Dx panel would be the first commercially available IVD for APOE genotyping and will detect all APOE genotypes (APOE2, APOE3, APOE4) which can play a role in the diagnosis of Alzheimer’s disease. People carrying the APOE4 genotype have a greater risk of developing Alzheimer’s which is the most common cause of dementia and are likely to do so earlier in life in comparison to others.

Seegene (Seoul, South Korea; www.seegene.com), a leading PCR molecular diagnostics company, and Werfen (Barcelona, Spain; www. werfen.com), a global diagnostics specialist, have finalized a partnership agreement as part of a technology-sharing initiative. The agreement outlines plans for the two companies to establish a NewCo in Spain, named Werfen-Seegene, following required government approvals, expected by the first half of 2025.

LGC (London, UK; www.lgcgroup.com) has made an addition to its growing global clinical diagnostics and genomics portfolio by acquiring DiaMex (Heidelberg, Germany; www.diamex.com), a manufacturer of third-party serology and molecular quality controls used in clinical laboratories and blood banks across the world. LGC is a global leader in life science tools, committed to collaborating with customers to provide solutions that address critical challenges in diagnosing, treating, feeding, and protecting the growing global population

ALPHABETICAL LISTING OF COMPANIES

77 Elektronika

Hungary • Budapest

Tel: (36) 1-206-1480

e77.hu

sales@e77.hu

Fully automated and semi-automated urine analyzers, blood glucose meters, rapid test readers and their consumables under own brand name, as well as OEM and ODM products for market-leading multinational companies.

AADEE

Argentina • Buenos Aires

Tel: (54) 11 45234848 aadee.com info@aadee.com.ar

Clinical laboratory products include an analyzer for blood gases and pH as well as an automatic electrolyte analyzer for measurement of Na, K, Cl, Ca.

AB Analitica

Italy • Padua Tel: (39) 049-0761698 abanalitica.com

sales@abanalitica.it

Specializes in qualitative and quantitative determination of nucleic acids, development of biobanking management systems, and in vivo/ in vitro diagnostics with breath test technology and the use of stable isotopes.

Abbott Diagnostics

USA • Abbott Park, IL

Tel: (1) 224-667-6100 www.diagnostics.abbott

Provides full range of in vitro diagnostics products, instrument systems, and tests. Products offer diagnostic solutions in point of care, immunoassay, clinical chemistry, hematology, blood screening, molecular, and informatics.

Absology

Korea • Anyang

Tel: (82) 31-348-8637 www.absology.co.kr

sales@absology.co.kr

In vitro diagnostic medical devices. ABSOL, which is an in-vitro-diagnostic immunoassay system, is one of the main items of the company. The system consists of an analyzing device and a test kit and takes about 5-30 minutes to check the test result.

Access Bio, Inc.

USA • Somerset, NJ Tel: (1) 732-873-4040 accessbio.net

info@accessbio.net

Focuses on rapid and early detection of infectious diseases with IVD test kits, biosensor, and molecular diagnostic products.

AccuBio Tech

China • Beijing

Tel: (86) 10-8048-4980

accubiotech.com

sales@accubiotech.com

Products include tests for pregnancy, infectious diseases, sexually transmitted diseases, fecal occult blood, tumor markers, drugs of abuse, blood glucose, and urine reagent strips.

Although all material in this directory is compiled from sources believed reliable, publisher cannot be held liable for any errors, omissions or inaccuracies. Inclusion, or lack of it, in this directory, does not constitute any endorsement or expression of other opinion by publisher with regard to companies, their products or services.

Accumax Lab Devices

India • Gandhinagar Tel: (91) 2674-248241 accumaxlab.com

contact@accumax-neaution.com

Produces an extensive range of liquid handling products under the Accumax brand such as pipettes and pipette Controllers, bottle top dispensers, tips, tubes, and PCR consumables.

Acon Laboratories

USA • San Diego, CA Tel: (1) 858-875-8000

aconlabs.com

info@aconlabs.com

The product line includes analyzers, devices, and test kits in the areas of immunoassays, molecular diagnostics, hematology, as well as a range of point of care testing solutions.

Adaltis

Italy • Rome Tel: (39) 0774-5791 adaltis.net

info@adaltis.net

In vitro diagnostic systems and reagent products to detect viral

infections, diagnose immune system diseases, and measure human hormone responses.

Advanced Instruments

USA • Norwood, MA Tel: (1) 781-320-9000 aicompanies.com info@aicompanies.com

Product range includes osmometers based on freezing-point depression technology, CSF cell counters, neonatal bilirubin analysis systems, among others

AESKU Diagnostics

Germany • Wendelsheim Tel: (49) 6734-9622-0 aesku.com

sales@aesku.com

Distributes ELISA kits for diagnostics of autoimmune diseases, including the AESKULISA product line. The main indications are rheumatology, antiphospholipid syndrome (APS), vasculitis, gastroenterology, hepatology, and diabetes.

LabMedica 400

AGD Biomedicals

India

• Mumbai

Tel: 91-22-28231061

agdbio.com sales@agdbio.com

Provides analyzers and reagents for clinical chemistry, electrolytes, hematology, coagulation and equipment for histopathology.

Agena Biosciences

USA • San Diego, CA Tel: 1(858) 882-2800 agenabio.com

Products and services based on core technology MassARRAY system, with a wide range of applications in tumor profiling, liquid biopsy, pharmacogenetics, sample integrity, and others.

Agilent

USA • Santa Clara, CA

Tel: (1) 800 227 977 agilent.com orders@agilent.com

Provides laboratory instruments, consumables, software and other services for a variety of markets. Diagnostic products offer solutions in pathology, genomic testing, specific proteins, and many other areas.

ALCOR Scientific

USA • Smithfield, RI Tel: (1) 401-737-3774 alcorscientific.com info@alcorscientific.com

Manufactures, markets, and distributes clinical laboratory instrumentation such as the iSED for ESR testing.

Agappe

Diagnostics

Switzerland

Switzerland • Cham Tel: (41) 41-780-60-10 agappe.com info@agappeswiss.com

Complete range of reagents and equipment for clinical chemistry and analytical needs. Products cover the areas of biochemistry, hematology, specific proteins, hemostasis, coagulation, urinalysis, molecular diagnostics, preanalytical and more.

AHN

Biotechnologie

Germany • Nordhausen (49) 3631 65242-0 ahn-bio.com

info@ahn-bio.com

The company encompasses three main brands of CAPP, AHN, and Maxxline, offering a wide selection of products for liquid handling, benchtop equipment, cryopreservation, and related laboratory consumables.

Aidian

Finland • Espoo (358) 10-309-3000

aidian.eu

aidian@aidian.eu

Provides point of care diagnostic systems to support rapid treatment decisions and microbiological tests for infection diseases such as

urinary tract infection.

Aikang

China • Shenzhen Tel: (86) 755-25871250 aikang-medical.com marketing@aikang-medical.com

Products include a range of chemiluminescence immunoassay analyzers, automatic ELISA systems, blood grouping systems, automated sample processing, blood banking, nucleic acid testing solutions, and laboratory consumables.

AirClean Systems

USA • Creedmoor, NC Tel: (1) 919-255-3220 aircleansystems.com sales@aircleansystems. com

Fume hoods, enclosures, and workstations designed to protect the operator or process from potentially harmful fumes, vapors, gases, and particulate.

Alfa Scientific Designs

USA • Poway, CA Tel: (1) 858-513-3888 alfascientific.com sales@alfascientific.com

The company focuses on rapid immunoassays including those for the detection of drugs of abuse, fertility hormones, infectious diseases, cardiac and cancer markers.

Alifax

Italy • Padua Tel: (39) 49-099-2000 alifax.com info@alifax.com

Focuses on the fields of hematology, microbiology, serology, and autoimmunity. Products of note include clinical diagnostic instrumentation for the analysis of erythrocyte sedimentation rate (ESR) and rapid bacterial culture.

Allsheng Instruments

China • Hangzhou Tel: (86) 571-88859758 allsheng.com sales@allsheng.com

Specializes in instruments for biological sample preparation, including nucleic acid extraction systems and automated NGS library preparation. Other products include devices for molecular POCT, automatic liquid handling instrumentation, and laboratory benchtop equipment and consumables.

ALPCO

USA • Salem, NH Tel: (1) 603-893-8914 alpco.com

cs@alpco.com

Specializes in immunodiagnostics and molecular diagnostics, with clinical diagnostic solutions for stoolbased gastroenterology, infectious and genetic disease, autoimmune disease, and metabolic disorders.

Alpha Laboratories

UK • Eastleigh, Hampshire Tel: (44) 23-8048-7209 alphalabs.co.uk export@alphalabs.co.uk

Supplies a wide range of laboratory and diagnostic products, including its own brand lines of pipettes and liquid handling systems, containers, disposables, and specimen transport packaging.

AMEDA Labordiagnostik

Austria • Graz Tel: (43) 316-698069 amp-med.com office.graz@amp-med.com

Offers a range of products known under the AMP Diagnostics brand, including kits and equipment for clinical chemistry, immunology, hematology and coagulation, as well as urine and rapid diagnostics.

Analyticon Biotechnologies

Germany • Lichtenfels Tel: (49) 6454-7991-0 analyticon-diagnostics.com info@ analyticon-diagnostics.com Focuses on solutions for urine diagnostics and hematology. Products include urine test strip analyzers, urine controls, hematology analyzers and reagents.

Anbio

Biotechnology

Germany • Frankfurt Tel: (1) 617-480-9213 anbio.com

Diagnostic and POCT devices and assays for CLIA, FIA, lateral flow immunoassays, as well as RT-PCR, and LAMP testing solutions. The product range covers cancer, cardiovascular conditions, inflammation, renal function, infectious diseases, and drugs of abuse tests.

Ansh Labs

USA • Webster, TX Tel: (1) 281-404-0260 anshlabs.com sales@anshlabs.com

Specializes in immunoassays with potential applications in reproductive medicine, glucagon regulation, neurodegenerative disorders, oncology, etc. Company’s products consist of emerging and maturing assays and monoclonal antibody development.

Apacor

UK • Wokingham Berkshire Tel: (44) 118-9795566 apacor.com info@apacor.com

Products are designed for microbiology and clinical chemistry applications and testing procedures, and specialize in parasitology.

Apel

Japan • Saitama Tel: (81) 48-280-3055

apel.co.jp

sales@apel.co.jp

Medical and analytical devices including hemoglobin and bilirubin meters, as well as colorimeters and spectrophotometers.

Apex Biotechnology

Taiwan • Hsinchu Tel: (886) 3-564-1952 apexbio.com info@apexbio.com

Handheld testing and monitoring systems for glucose, uric acid, hemoglobin, cholesterol, lactate, HbA1C, ketone, coagulation and multifunctional self-testing systems.

Arkray Healthcare

India • Surat Tel: (91) 98-7904-3958 arkray.co.in export@arkray.co.in

In-vitro rapid test kits and biochemistry reagents. Provides rapid kits for infectious disease, including HIV, HCV, HBsAg, vector borne diseases such as malaria and dengue, and serology kits including widal, RF, ASo and CRP.

Asan Pharmaceutical

Korea • Seoul

Tel: (82) 2-3290-5700 asanpharm.co.kr global@asanpharm.co.kr

In vitro diagnostic reagents for infectious diseases, gastrointestinal disease, tumor markers and more, as well as FIA test analyzer, culture mediums, and PCR kits.

Assure Tech

China • Hangzhou

Tel: (86) 571-4008535577 Diareagent.com contact@diareagent.com

Offers comprehensive and rapid testing solutions in the areas of drugs of abuse, infectious disease, fertility, tumor markers, cardiac markers, biochemical, allergy and chronic disease, as well as instruments including CLIA and FIA analyzers, fully automatic biochemistry analyzer, handheld DOA reader and portable coagulation analyzers.

Astell Scientific

UK • London

Tel: (44) 0-208-309-2031 astell.com sales@astell.com

Autoclaves for the sterilization of laboratory apparatus, media, and discard, including large chamber autoclaves suitable for sterilizing cultures and lab equipment in high quantities.

Astra Biotech

Germany • Berlin

Tel: (49) 0-30-74-696-509 astrabiotech.de info@astrabiotech.de

Offers a wide range of reagents and diagnostic kits for detection of human hormones, allergens, tumor markers, infections, and genetic disorders based on

ELISA, real-time PCR, and microarray technologies.

Atlas Link

USA • Manassas, VA Tel: (1) 703-366-3851 atlaslink-inc.com info@atlaslink-inc.com

IVD test kits and supplies generic and branded pharmaceuticals, medical disposables, medical, and laboratory equipment, and blood glucose and cholesterol monitoring products.

Atomo Diagnostics

Australia • Leichhardt, NSW Tel: (61) 460-772-000 atomodiagnostics.com

Supplies unique, integrated rapid diagnostic test (RDT) devices and finished pointof-care rapid lateral flow tests to global markets. The company makes rapid point of care testing easier, more efficient, faster and less costly than typical multi-component/multi step tests.

AUDIT MicroControls

USA • Eatonton, GA Tel: (1) 866-252-8348 auditmicro.com customerservice@ auditmicro.com

Supplies daily quality control and calibration verification/ linearity materials to clinical laboratories worldwide.

Autobio Diagnostics

China • Zhengzhou Tel: (86) 371-6798-5313 en.autobio.com.cn info@ autobio-diagnostics.com

Clinical diagnostic products including ELISA, chemiluminescence immunoassays, microbiology, and POCT

AVE Science & Technology

China • Changsha Tel: (86) 731-8892-5308 c-ave.com ibd.ave@c-ave.com

The main products include urine analyzers, urine formed elements analyzer, multi-function microscopy analyzer, feces analyzer as well as related reagents and quality controls.

Awareness Technology, Inc.

USA • Palm City, FL Tel: (1) 772-283-6540 awaretech.com sales@awaretech.com

Manufactures automated and semi-automated systems with emphasis on quality, reliability, and economy. Products include chemistry analyzers and microplate assays and equipment for routine health screening plus allergy, autoimmune and infectious disease testing.

Axiom Diagnostics

Germany • Bürstadt Tel: (49) 6206-6012 axiom-solutions.de

info@axiom-solutions.de

Offers a wide range of equipment in the areas of rapid tests, ELISA, CLIA, coagulation, hematology, blood banks, and laboratory equipment, among others. B&E Bio-Technology

China • Yantai Tel: (86) 535-6718181 besic.com info@besic.com

Manufactures a series of 3 and 5 diff hematology analyzers, multi-biosensor-based electrolyte analyzers, hemoglobin analyzer and POC blood gas analyzer.

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Baebies

USA • Durham, NC Tel: (1) 919-891-0432 baebies.com

techsupport@baebies.com

Specializes in newborn screening and near-patient pediatric testing with platforms and solutions based on digital microfluidics technology.

BBI Solutions

UK • Crumlin Tel: (44) 0-1495-363000 bbisolutions.com info@bbisolutions.com

Produces immuno-diagnostics reagents ranging from human antigens, antibodies, gold nanoparticles and conjugates, enzymes, and serum and plasma products.

BD Diagnostics

USA • Franklin Lakes, NJ Tel: (1) 201-847-6800 www.bd.com

Molecular diagnostic systems, flow cytometers, immunossay analyzers, automated blood culturing systems and other products in the areas of microbiology, POC, and lab automation.

Beckman Coulter USA • Brea, CA Tel: (1) 714-993-5321 beckmancoulter.com Laboratory systems, analyzers, reagents, and other solutions for clinical chemistry, immunology, microbiology, urinalysis, hematology, and other areas.

Benchmark

Scientific

USA • Sayreville, NJ Tel: (1) 908-769-5555

benchmarkscientific.com info@ benchmarkscientific.com

Products include dry baths, homogenizers, hotplate stirrers, pipettes, shakers, rockers, vortex mixers, thermal cyclers, and centrifuges.

Berthold Technologies

Germany • Bad Wildbad Tel: (49) 7081-177-0

berthold.com

info@berthold.com

A broad line of bioanalytical instruments including gamma counters, luminometers, flurometers, imaging systems, and HPLC detectors.

Bio-Rad Laboratories

USA • Hercules, CA

Tel: (1) 510-724-7000

bio-rad.com support@bio-rad.com

Full range of instrumentation, reagent kits, software and QC systems to clinical laboratories. Areas of expertise include quality control, diabetes screening, multiplex autoimmune and infectious serology testing, HIV test systems, molecular diagnostics, and blood bank testing.

BIOBASE

China • Jinan

Tel: 86-531-81219803 biobase.cc export@biobase.com

Full range of in vitro diagnosis (IVD) instruments and reagents, laboratory equipment, sterilization equipment, PCR equipment, cold chain products, and more.

Biocare Medical

USA • Pacheco, CA

Tel: (1) 925-603-8000

biocare.net

Provides Automated immunohistochemistry (IHC) instrumentation, and the full range of reagents for IHC and in situ hybridization (ISH; RISH) testing.

Biocartis

Belgium • Mechelen (32) 15-632-600 biocartis.com info@biocartis.com

Develops diagnostics technology platforms for multiplexed detection of bio-analytes with a focus on oncology testing.

BioCheck

USA • South San Francisco, CA

Tel: (1) 650-573-1968 biocheckinc.com info@biocheckinc.com

In vitro diagnostic immunoassay devices, antibodies, and testing kits. Product categories include tumor markers, cardiac markers, steroids, TORCH, infectious diseases, thyroids, and fertility.

Bioclin

Brazil • Belo Horizonte

Tel: (55) 31 3439-5454 bioclin.com.br sales@bioclin.com.br

Offers a wide variety of kits for biochemistry, turbidimetry, agglutination in latex, ELISA, coagulation, dyes, anticoagulants, cleansing solutions and real time PCR.

Bioer Technology

China • Hangzhou

Tel: (86) 571-8777-4575 bioer.com.cn overseas@bioer.com.cn

Real-time fluorescence quantitative PCR instruments, automatic nucleic acid purification instruments, thermal cycler, dry baths, PCR detection reagents, mobile PCR laboratory, molecular detection consumables and PCR raw materials.

Biohit HealthCare

Finland • Helsinki

Tel: (358) 9-773-861 biohithealthcare.com info@biohit.fi

Specializes in products and analysis systems for the early diagnosis and prevention of gastrointestinal diseases.

Biolabo

France • Maizy

Tel: (33) 323 25 15 50 biolabo.fr sales@biolabo.fr

Produces reagents, calibrators and controls, and

automated analyzers for biochemistry and hemostasis.

Biomat

Italy • Santa Margherita di Ala

Tel: (39) 0464-357951 biomat.it info@biomat.it

Microplates and other articles for ELISA, molecular biology, HTS-TC, and research, with a complete range of surfaces and coatings for all applications.

Biomerica

USA • Irvine, CA Tel: (1) 949-645-2111 biomerica.com info@biomerica.com

Diagnostic products for disease detection in the areas of cardiology, diabetes, infectious diseases, and others. The company’s primary research and development focus is on gastrointestinal and inflammatory diseases.

BioMerieux

France • Marcy l’Etoile Tel: (33) 4-7887-2000 biomerieux.com

In vitro diagnostic systems in the areas of molecular diagnostics, microbiology and immunoassay.

Bioneer

Korea • Daejeon Tel: (82) 42-939-6333 bioneer.com sales@bioneer.com

Solutions for molecular diagnostics including nucleic acid extraction instruments, real-time PCR instruments and diagnostic kits for infectious diseases.

BioPerfectus

China • Shanghai Tel: (86) 021-64193032 www.bioperfectus.com info@bioperfectus.com

Molecular diagnostic solutions for infectious diseases. The company manufactures products ranging from real time PCR kits, nucleic acid extraction systems, rapid tests and automation laboratory devices, etc.

BioPorto Diagnostics

Denmark • Hellerup Tel: (45) 4529-0000 bioporto.com info@bioporto.com

Biomarkers, research antibodies and assays for scientists and clinicians worldwide. Products include the NGAL test for rapid risk assessment of acute kidney injury (AKI).

BIORON Diagnostics

Germany • Speyer Tel:(49) 6232-298-450 bioron.net info@bioron.net

Wide range of open-system, real-time PCR kits for the detection of pathogens, especially STIs.

Biosigma

Italy • Cantarana Di Cona

Tel: (39) 04-26-302226 biosigma.com export@biosigmaeu.com

Disposable plastic items for

biotechnology, research, clinical chemistry, and pharmaceutical laboratories.

Biosynex

France • Strasbourg Tel: (33) 3-88-78-7887 biosynex.com client.pro@biosynex.com IVD medical devices in the areas of rapid diagnostic tests (RDT), immunoblot, molecular biology, and POC testing for screening, diagnosis and prevention.

BioSystems

Spain • Barcelona Tel: (34) 93-311-00-00 biosystems.es biosystems@biosystems.es Analyzers and reagents for clinical chemistry, coagulation, hematology, autoimmunity and serology.

LabMedica 400

Bio-Techne

USA • Minneapolis, MN

Tel: (1) 612-379-2956

bio-techne.com

High-quality reagent solutions, providing assays, quality controls, calibrators, reagents, proficiency testing materials.

Biotech Company

Nanchang

China • Nanchang Tel: (86) 791-8816-8831 biotech.com.cn overseas@biotech.com.cn

Provides a range of diagnostic instruments and reagents for medical and clinical applications.

Biotécnica

Brazil • Varginha Tel: (55) 35-3214-4646 biotecnica.ind.br

sac@biotecnica.ind.br

Equipment, reagents, controls and calibrators in the areas of biochemistry, turbidimetry, coagulation, urinalysis, hematology, among others.

Biotime

Biotechnology

China • Xiamen Tel: (86) 0592-688-1190 xiamenbiotime.com info@biotime.cn

Products include rapid tests for infectious diseases, immunofluorescence assays and analyzers, CLIA analyzer, and testing solutions for COVID19 and diabetes management.

Biotron Diagnostics

USA • Hemet, CA Tel: (1) 951-658-7766 biotrondiagnostics.com

&

Thermo-Resistant (- 60 °C to 300 °C) Fully Washable & Flexible Suitable for central sterilization services Sterilizable

sales@ biotrondiagnostics.com

Complete line of in-vitro diagnostic kits and reagents for use in hospitals, laboratories, and research institutions.

BioVendor Group

Czech Republic • Brno

Tel: 420 549 -24185

info@biovendor.group biovendor.group

Immunodiagnostic and molecular diagnostic products, presenting key products lines for CLIA, NGS, Microblot Array, microRNA and LAMP. The group brings together well-known brands of TestLine (infectious diseases and immunology), ViennaLab (human genetic testing) and DiaSource (endocrinology, autoimmune and infectious diseases).

Blue Cross

Bio-Medical

China • Beijing Tel: (86) 10-6975-6015 bcbmo.com

bluecross@bcbmo.com

Main products include the test strips and cassettes for fertility, autoimmune diseases, drugs of abuse, infectious diseases, tumor markers, and sexually transmitted diseases.

Boditech Med

Korea • Chuncheon (82) 33-243-1400

boditech.co.kr/en

sales@boditech.co.kr

Produces a diverse range of tests with a small amount of sample volume. Available markers for cardiac, cancer, COVID-19, diabetes, hormones, infection, autoimmune, and molecular diagnostics. Instrument systems for immunodagnostics and POC testing.

Boule Medical

Sweden • Spanga Tel: (46) 8-7447700 boule.com info@boule.se

Hematology diagnostics, focusing on near-patient, decentralized blood diagnostics. The company’s product include a range of hematology analyzers, reagents and controls from its three main brands: Swelab, Medonic and Exigo.

Brand

Germany • Wertheim

Tel: (49) 9342-808-0 brand.de info@brand.de

Laboratory equipment and instruments, including a wide range of liquid handling products, pipetting robots, volumetric instruments, consumables, and labware for processing and storing samples.

Brooks Automation

USA • Chelmsford, MA

Tel: (1) 978-262-2400 brooks.com/laboratory-automation

Automation products for a range of clinical diagnostic applications, including specimen sorting, decapping, sealing, aliquoting and archiving.

Bruker

USA • Billerica, MA

Tel: (1) 978-663-3660 bruker.com

Offers high-value analytical and diagnostic solutions in a variety of sectors. Leading provider of MALDI-TOF mass spectrometry technology, offering instrumentation and assays for clinical microbiology.

Bühlmann

Laboratories

Switzerland • Schönenbuch

Tel: (41) 61-487-12-12 buhlmannlabs.ch info@buhlmannlabs.ch

Specializes in fecal calprotectin assays, offering the largest calprotectin product range including rapid testing, ELISA, and automated solutions. Other products include unique assays for cellular allergy, neuroimmunology, autoimmunity, and clinical chemistry.

Calbiotech

USA • El Cajon, CA Tel: (1) 619-660-6162 calbiotech.com

Immunoassay development and manufacturing, with a comprehensive range of ELISA and CLIA assays, including specific assays for hormone, autoimmune disorders, cancer, infectious diseases and more.

Callegari

Italy • Parma

Tel: (39) 05-21-273274 callegari1930.com info@catellanigroup.com

Point of care screening devices for near patient testing in the areas of cardiovascular health, diabetes, hematology, liver function, and oxidative stress.

CANDOR Bioscience

Germany • Wangen Tel: (49) 7522-795270 candor-bioscience.de info@candor-bioscience.de

Comprehensive selection of premium solutions for immunoassays. Products include HAMA and interference blockers, surface blockers, stabilizers and buffer solutions for immunoassays

CareHealth America

USA • Blue Earth, MN Tel: (1) 507-526-3951 drugcheck.com sales@drugcheck.com

DrugCheck onsite urine and saliva screening devices for the detection of over 50 DOA and cutoffs, as well as a growing catalog of rapid alcohol screening and health diagnostics devices.

Caretium Medical Instruments

China • Shenzhen Tel: (86) 755-2527-3885 en.caretium.com info@caretium.com

Products include hematology analyzers, electrolyte analyzers, biochemistry analyzers, microplate readers and washers, ESR analyzers, HbA1c analyzers, coagulometers, urine analyzers, and reagent products.

Carewell Biotech

India • New Delhi Tel: (91) 11-4153-9602 carewellindia.com info@carewellindia.com

Diagnostic products such as electrolyte analyzers and blood glucose monitoring systems in several countries under OEM brands.

Carolina Liquid Chemistries

USA • Greensboro, NC Tel: (1) 336-722-8910 carolinachemistries.com contactsales@carolinachemistries.com

Clinical chemistry analyzers and reagents, providing reagents for use on common platforms. The company also manufactures its own brand reagents and chemistry analyzers for clinical laboratories of all sizes.

Carperlabs

Colombia • Bogota Tel: (57) 310-763-20-91 carperlabs.co ventas@carperlabs.co

Reagents for in vitro diagnositcs for use in clinical laboratories and blood banks.

CDG Biotech Corp

USA • Westlake Village, CA Tel: (1) 805 2220877 cdgbiotech.com info@cdgbiotech.com

Novel-clinical diagnostics for labs and physicians to meet patient care needs. The company offers a solid-phase immunoassay designed for in-vitro quantitative measurement of hormones and other biomarkers.

CellaVision

Sweden • Lund Tel: (46) 46-460-1600 cellavision.com info@cellavision.com

Provides digital microscopy solutions for hematology. Its product portfolio, which covers analyzers, instruments, reagents, and software, helps laboratories automate and simplify the process of analyzing blood and other body fluids.

Cepheid

USA • Sunnyvale, CA Tel: (1) 408-541-4191

cepheid.com

cepheid@cepheideurope.fr

Automated molecular diagnostics. Its GeneXpert System platform combines on-board sample prepa-

ration with real-time PCR amplification and detection, for fully integrated and automated nucleic acid analysis.

Certest Biotec

Spain • San Mateo de Gallego, Zaragoza Tel: (34) 976-520-354 certest.es

certest@certest.es

IVD diagnostic products including RT-PCR, rapid test, turbidimetry and CLIA tests.

Chema Diagnostica

Italy • Monsano Tel: (39) 731-605-064 chema.com

mail@chema.com

Wide range of liquid stable reagents for the clinical chemistry and immunochemistry industries.

Chemclin Biotech

China • Beijing Tel: (86) 10 5871 7511 chemclin.com

BD@chemclin.com

Clinical chemistry systems and immunodiagnostic systems, specializing in chemiluminescence immunology with the proprietary technology platform of Light-initiated Chemiluminescence Immunoassay (LiCA).

Chemclin

Diagnostics

China • Shanghai Tel: (86) 21-68129988 chemtronbio.com international@ chemtronbio.com

Point-of-care (POC) in vitro immunodiagnostic rapid tests for the detection and management of pregnancy and fertility, cardiovascular disease, cancers, drugs of abuse, COVID-19 and other infectious diseases.

Chromagar

France • Paris

Tel: (33) 1-45-48-05-05 chromagar.com chromagar@chromagar. com

Wide range of chromogenic culture media, covering applications in clinical bacteriology, industrial microbiology, quality control. These media allow for a quicker and simpler detection of key clinical and food-borne pathogens.

Chromsystems

Instruments & Chemicals

Germany • Munich

Tel: (49) 89-18930-0 chromsystems.com

Routine clinical diagnostics solutions for high-performance liquid chromatography (HPLC) and tandem mass spectrometry (LC-MS/ MS). Products include assays with a large parameter menu covering newborn screening, therapeutic drug monitoring, steroid analysis, vitamin profiling and more.

Clinisys

USA • Tuscon, AZ

Tel: (1) 520-570-2000 clinisys.com

Laboratory informatics software. Provides information solutions for laboratories in various fields.

CLONIT

Italy • Milan Tel: (39) 02-5681-4413 clonit.it info@clonit.it

Products for in vitro diagnostics with particular attention to the detection of viral, bacteria, and protozoa infections, genetic mutations, and oncological diseases. Products available include ready-to-use diagnostic kits that are user-friendly for routine diagnostic laboratories.

Co-Diagnostics, Inc. (Co-Dx)

USA • Salt Lake City, UT (1) 801-438-1036 co-dx.com info@co-dx.com

State-of-the-art diagnostics for the detection and/ or analysis of DNA or RNA molecules using proprietary technology. The company has a robust menu of in vitro test kits available for use by clinical laboratories in the US as well as in India via its joint venture, CoSara.

Copan Diagnostics

USA • Murrieta, CA Tel: (1) 951-696-6957 copanusa.com info@copanusa.net

Products for sample collection and transport systems, full laboratory automation, digital microbiology and artificial intelligence (AI) for microbiology.

Coris

BioConcept

Belgium • Gembloux Tel: (32) 81-719-917 corisbio.com info@corisbio.com

Rapid diagnostic kits for the detection of human respiratory, gastro-enteric and blood-borne pathogens, and for the detection of antibiotic resistance markers.

Cormay

Diagnostics

Poland • Warsaw Tel: (48) 22-751-79-10 cormaydiagnostics.com international@cormay.com

Range of products for clinical chemistry, hematology, electrophoresis, coagulation, and specific proteins.

Cornley High-Tech

China • Shenzhen Tel: (86) 755-8633-0432 cornley.com sales@cornley.com

Diagnostic analyzers, including equipment for electrolytes analysis, blood gas analysis, and TCO2 analysis.

CTK Biotech

USA • Poway, CA Tel: (1) 858-457-8698

ctkbiotech.com

info@ctkbiotech.com

Immunodiagnostic tools and point of care diagnostic test kits. Products focus on tropical diseases, parasitic infections, gastrointestinal illnesses, bloodborne, biomarkers, hepatitis, STD, respiratory and hormone tests.

Cytognos

Spain • Salamanca Tel: (34) 923-125-067 cytognos.com

admin@cytognos.com

Focuses on clinical flow cytometry solutions. Offers reagents, devices and software to flow cytometer laboratories.

D-tek

Belgium • Mons Tel: (32) 65-84-18-88 d-tek.be

info@d-tek.be

Diagnostic products for autoimmunity and gastroenterology, including the BlueDot and BlueWell product lines, and along with liquid substrates and stabilizers.

Daan Gene China • Guangzhou Tel: (86) 20-3206-8126 en.daangene.com marketing@ daangenel.com

Diagnostic test kits for infectious diseases, automatic nucleic extraction systems, real-time PCR systems, automatic CLIA analyzer and liquid based cytology instruments.

Das Italy • Palombara Sabina Tel: (39) 0774-637070 dasitaly.com

info@dasitaly.com

Electronic automated instruments in the IVD field for full automation of ELISA, IFA, BLOT and other devices in clinical chemistry and pediatric testing.

Deltalab

Spain • Barcelona Tel: (34) 93-699-5000 deltalab.es deltalab@deltalabgroup. com

Laboratory disposable and re-usable products covering most requirements in hospitals, industry, education, and research. Products include sample containers, swabs, test tubes, histology stains, industrial bottles, test tube racks and many other lab items.

Denka Japan • Tokyo Tel: (81) 3-6214-3236 www.denka.co.jp info@denka-seiken.com

In vitro diagnostic reagents. Top export products include direct and automatable HDL and LDL reagents, latex-enhanced serum protein tests for hsCRP, rheumatoid factor, myglobin, ferritin and others, as well as rapid diagnostic test kits.

DFI

Korea • Gimhae

Tel: (82) 55-346-1882

dficare.com

info@dficare.com

IVD products for urinalysis, including a line of urine chemistry analyzers. Other products include urine test strips, lipid profile testing, hemoglobin meters and rapid screening of infectious diseases and other markers.

DIA.PRO

Diagnostic Bioprobes

Italy • Milan

Tel: (39) 02-2700-7161

diapro.it

info@diapro.it

IVD solutions for infectious diseases such as COVID-19, TORCH, retrovirus, hepatitis, emerging tropical diseases as well as blood screening and autoimmunity.

Diagast

France • Lille

Tel: (33) 3-20-96-53-53 diagast.com contact@diagast.com

Specializes in the transfusion field, and produces its own immunohematology cells lines, monoclonal antibodies and develops the reagents associated to E.M. technology, microplates, and manual techniques.

DiagCor

China • Hong Kong

Tel: (852) 2147-4088 diagcorlifescience.com sales@diagcorlifescience.com

Specializes in flow-through hybridization technology for molecular diagnostics. The company operates in the areas of infectious disease identification, oncology, and genetic testing, offering a wide range of in vitro diagnostic (IVD) systems, instruments, and test kits for DNA, RNA and protein rapid analysis.

Diagnostic Automation/Cortez Diagnostics

USA • Calabasas, CA

Tel: (1) 818-591-3030 rapidtest.com onestep@rapidtest.com

Rapid tests, ELISA, IFA, chemiluminescence, and serology kits.

Diagon

Hungary • Budapest Tel: (36) 1-369-6500 diagon.com sales@diagon.com

Instruments for hematology and hemostasis, as well as reagents for a broad range of analyzers in the areas of hematology, coagulation, and molecular diagnostics.

Dialab

Austria • Wiener Neudorf

Tel: (43) 2236-660910-0 dialab.at office@dialab.at

Complete range of diagnostic products from clinical chemistry reagents, immunological reagents, blood grouping reagents, and more. Instruments include clinical chemistry analyzers, photometers, as well as instruments for ELISA, coagulation, and urine strip testing.

Diamond Diagnostics

USA • Holliston, MA

Tel: (1) 508-429-0450 diamonddiagnostics.com info@diamonddiagnostics.com

Manufactures several lines of electrolyte analyzers. Other products include alternative consumables, such as reagents, quality controls, electrodes and other accessors.

DiaSorin

Italy • Saluggia

Tel: (39) 0161-4871

diasorin.com

marketing@diasorin.it

In vitro diagnostics reagent kits used in immunodiagnostics and molecular diagnostics. Areas of specialty include infectious diseases, cardiac markers, bone metabolism, hepatitis and retrovirus, oncology, and endocrinology.

DiaSource ImmunoAssay

Belgium • Louvain-La-Neuve Tel: (32) 10-84-99-11 diasource-diagnostics.com info@diasource.be

Clinical diagnostic products that focus on endocrinology and infectious diseases.

DiaSys Diagnostic Systems

Germany • Holzheim Tel: (49) 6432-9146-0 diasys-diagnostics.com info@diasys.de

Diagnostic systems for clinical chemistry and immunoturbidimetry. Supplies high-quality reagents for routine and special diagnostics, as well as automated analyzers for laboratory and POC.

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Diatron

Hungary • Budapest Tel: 36 1-2794-400 diatron.com sales@diatron.com

Hematology analyzers, reagents, and control material, plus clinical chemistry analyzers, reagents, and controls.

Diazyme Laboratories

USA • Poway, CA Tel: (1) 858-455-4768 diazyme.com sales@diazyme.com

Test kits and reagents for the diagnosis of cardiovascular disease, liver disease, cancer markers, renal disease, and electrolytes.

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Diesse Diagnostica

Senese

Italy • Siena Tel: (39) 0577-30-7110 diesse.it contacts@diesse.it

Diagnostic systems primarily in the field of immunodiagnostics and automatic measurement of erythrocyte sedimentation rate (ESR). Products include a line of automated ESR systems and multi-parametric immunoassay analyzer.

Diestro

Argentina • Buenos Aires Tel: (54) 11-4709-7707 diestroweb.com info@diestroweb.com

Specializes in electrolyte analyzers for labs of all sizes,

consumables, and ISE module for OEM customers.

Dirui Industrial

China • Changchun Tel: (86) 431-8508-3721 en.dirui.com.cn dirui@dirui.com.cn

In vitro diagnostic products in the fields of biochemistry, urinalysis, hematology, chemiluminescence immunoassay, gynecology, blood coagulation analysis, molecular diagnostics, and integrated laboratory.

Drucker Diagnostics

USA • Port Matilda, PA Tel: (1) 814-692-7661 druckerdiagnostics.com sales@druckerdiagnostics. com

Wide range of centrifuges including STAT, routine, compact benchtop and adaptable centrifuges.

DWK Life Sciences

Germany • Mainz Tel: 49 (0) 6131-1445 4131 www.dwk.com sales@dwk.com

DWK Life Sciences brings together three leading manufacturers of precision glassware, laboratory consumables and specialty products for life sciences, in the globally recognized brands DURAN, WHEATON and KIMBLE.

DxGen

Korea • Gunpo Tel: (82) 31-427-8450 dxgenco.com sales@dxgenco.com

Point-of-care solutions to measure HbA1c, CRP, hs-CRP, Urinary Albumin, D-dimer, Hemoglobin, Vitamin-D, Glycated Albumin, COVID-19 antigens and antibodies.

Dymind

China • Shenzhen Tel: (86) 0755-2600-8015 dymind.com.cn

LabMedica 400

intl@dymind.com

Products include a comprehensive range of automatic hematology analyzers as well as devices for coagulation, immunology, biochemistry and point-of-care.

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Dynex

Technologies

USA • Chantilly, VA

Tel: (1) 703-631-7800 dynex.com customerservice@dynextechnologies.com

Fully-automated ELISA microplate processing systems and associated consumables and accessories.

Edan Instruments

China • Shenzhen

Tel: (86) 755-26898326 edan.com info@edan.com

In vitro diagnostic products include hematology analyzers and reagents as well as POC devices for blood gas analysis, immunoassays and molecular diagnostics.

EKF Diagnostics

UK • Cardiff Tel: (44) 29-20-710570 ekfdiagnostics.com info@ekfdiagnostics.com

Point-of-care diagnostics and central laboratory assays with hemoglobin, hematocrit, HbA1c, glucose and lactate analyzers.

ELGA LabWater

UK • High Wycombe Tel: (44) 0-203-567-7300 elgalabwater.com info@elgalabwater.com

Water purification systems for research and testing, healthcare, and clinical diagnostics applications.

ELITech Group

France • Paris

Tel: (33) 0-1-41-45-07-10 elitechgroup.com info@elitechgroup.com

In vitro diagnostic equipment and reagents for clinical chemistry, microbiology, molecular diagnostics, hematology, cytology, and sweat test systems.

Emperor Electronic Technology

China • Shenzhen Tel: (86) 0755-3689-9066 china-emperor.com info@china-emperor.com

In vitro devices including chemistry analyzers, urine analyzers, and immunology analyzers.

Eppendorf

Germany • Hamburg Tel: (49) 4053-8010 eppendorf.com eppendorf@eppendorf.com

Instruments, consumables, and reagents, including pipettes and automated pipetting systems, dispensers, centrifuges, mixers, spectrometers, and DNA amplification equipment as well as ultra-low temperature freezers, bioreactors, CO2 incubators, shakers, and cell manipulation systems

ERA Biology

China • Tianjin Tel: (86) 022-60978609 era-bio.com customer@era-bio.com

Specializes in invasive fungal disease diagnostics with products including rapid test such as aspergillus, cryptococcus and candida Ag/Ab, full-automatic CLIA System (FACIS), kinetic tube readers, and detection of bacterial endotoxin and fungus (1-3)-β-D-glucan.

Erba Mannheim

UAE • Dubai Tel: (420 517-077-111 erbamannheim.com sales@erbamannheim.com

Range of analyzers and reagents. Products focus on clinical chemistry, immunology, hematology, coagulation, critical care, urine analysis, diabetes monitoring, autoimmune and infectious disease monitoring, and microbiology.

Esco Lifesciences

Singapore • Singapore Tel: (65) 6542-0833 escolifesciences.com mail@escolife sciences.com

Delivers controlled environment, lab and cleanroom equipment solutions to the clinical, life science, research, and industrial laboratory community.

LabMedica 400

Esteriplas

Portugal •

Santa Maria da Feira

Tel: (351) 256-330350 esteriplas.pt

info@topstar.pt

Laboratory consumables, measuring equipment, safety and hygienic products.

Eurobio Scientific

France • Les Ulis

Tel: (33) 01-69 79 64 80 eurobio-scientific.com

info@eurobio-scientific.com

Complete range of reagents and biochemicals for the diagnostic and research markets.

Euroimmun

Germany • Lübeck

Tel: (49) 451-2032-0 euroimmun.com

info@euroimmun.de

Products for autoimmune and infection diagnostics, allergology and molecular diagnostics. The product range includes indirect immunofluorescence, ELISA, immunoblot, radioimmunoassay and molecular genetic test systems, as well as state-of-the-art instruments, software and automation systems.

Eurospital

Italy • Trieste

Tel: (39) 040 8997 1 eurospital.com

info@eurospital.it

Diagnostic medical devices for the in vitro diagnosis of Celiac diseases, inflammatory bowel disease, autoimmune disorders and infectious diseases.

Eurotrol

Netherlands • Ede

Tel: (31) 318-695-777 eurotrol.com

office@eurotrol.com

QC materials to the diagnostic laboratory market, EQA/PT programs, standardization bodies, hospital labs, and POC.

Everlife CPC Diagnostics

India • Chennai Tel: (91) 44-2499-3989 cpcdiagnostics.in info@cpcdiagnostics.in

Lab products that focus on clinical chemistry, hematology and coagulation, immunodiagnostics, molecular diagnostics and research, and pre-analytical automation.

Fapon Biotech

China • Dongguan Tel: (86) 769-22898886 en.faponbiotech.com market@fapon.com

IVD reagent raw materials, such as antigens, antibodies, and enzymes, as well as reagent solutions for rapid tests, molecular diagnostics ELISA, CLIA and biochemistry as well as innovative open instrument platforms.

Feather Safety Razor

Japan • Osaka Tel: (81) 6-6458-1638

feather.co.jp

overseas@feather.co.jp

Manufactures razor blades with technology and development capabilities centering on ultra-precision metal processing. Offers an expanded line of disposable microtome blades offering best cutting performance for sectioning of pathological specimen blocks.

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FL Medical

Italy • Torreglia, Padua (39) 049-5211475 flmedical.com info@flmedical.com

Laboratory equipment including blood collection tubes, serum separator tubes, pipette tips, specimen containers, microbiology products, and more.

Fortis Life Sciences

USA • Waltham, MA (1) 800.338.9579 fortislife.com

Portfolio of reagents for immunoassays including primary and secondary antibodies, kits, reagents, and accessories for use in IHC/ IF/ICC and ELISA; enzymes and reagents for PCR/qPCR, isothermal amplification, NGS sample preparation and library preparation; raw materials suitable for a wide range of diagnostic applications.

Fortress Diagnostics

UK • Antrim Tel: (44) (0) 2894-487676 fortressdiagnostics.com info@fortressdiagnostics. com

Offers a portfolio of POC and clinical diagnostic test kits across a spectrum of disciplines, including products for clinical chemistry, immunology, hematology and serology.

Fosun Diagnostics

China • Shanghai Tel: (86) 400-619-6063 fosundiagnostics.com customerservice@ fosundiagnostics.com

Diagnostic laboratory instruments and reagents in the fields of clinical chemistry, immunoassays, molecular diagnosis, microbiology, pathology and POCT.

FUJIFILM Wako

Pure Chemical Corp

Japan • Osaka Tel: (81) 6-6203-3741 ffwk.fujifilm.co.jp

Laboratory chemicals, specialty chemicals, and diagnostic reagents.

Fujirebio

USA • Malvern, PA Tel: (1) 610-240-3800

fujirebio.com

IVD testing solutions for clinical diagnostics and research use. Product lines span the range from specialized manual and automated testing to fully automated routine testing solutions.

GenBody

Korea • Cheonan Tel: (82) 41-523-8990 genbody.co.kr contact@genbody.co.kr

Diagnostic solutions such as rapid diagnostic tests, fluorescent immuno-diagnostic tests, ELISA, molecular diagnostic tests, and clinical chemistry tests.

General Biologicals Corporation (GBC)

Taiwan • Hsinchu City Tel: (886) 3-577-9221 gbc.com.tw sales.group@gbc.com.tw

High-quality IVD and pharmaceutical products for doctors to make clinical decisions in the area of hepatitis, tumor markers, retrovirus, fertility, thyroid and steroids.

GeneReach Biotechnology

Taiwan • Taichung City

Tel: (886) 4-2463-9869 genereach.com sales@genereachbiotech. com

Products for applied nucleic acid detection technology, including equipment and reagents, as well as diagnostic kits for the point-of-care market.

Genes2Me

India • Gurgaon Tel: (91) 8800821778 genes2me.com contact@genes2me.com

NGS clinical assay panels, molecular POC testing solutions, RT-PCR kits, rapid antigen/antibody testing kits, and molecular biology reagents.

Genesystem

Korea • Daejeon Tel: (82) 42-863-8551 genesystem.co.kr info@genesystem.co.kr

Specializes in molecular diagnostic solutions to target point-of-care testing applications. Provides state-ofthe-art diagnostic platforms for precise and convenient tests using its unique biochip technology.

Genetic Signatures

Australia • Newtown, NSW Tel: (61) 2 9870 7580 geneticsignatures.com info@geneticsignatures. com

Real-time PCR based products for the routine detection of infectious diseases under the EasyScreen brand, utilizing the company’s proprietary MDx platform technology.

Genrui Biotech

China • Shenzhen Tel: (86) 755-2683-5560 genrui-bio.com

info@genrui-bio.com

IVD equipment and reagents. Product range covers immunoassay, chemistry, hematology, urinalysis, and point-ofcare, as well as associated reagents.

Getein Biotech

China • Nanjing Tel: (86) 25-6856-8594 www.getein.com sales@getein.com.cn Range of rapid test kits for disease detection, as well as quantitative immunoassay analyzers.

Globe Scientific

USA • Mahwah, NJ Tel: (1) 201-599-1400 globescientific.com mail@globescientific.com

High quality laboratory plasticware, glassware items and scientific equipment. Products include cups and cuvettes for laboratory analyzers, an expanded line of tube racks, universal fit pipette tips, among others.

GMMC

Korea • Seoul Tel: (82) 2-2104-0470 gmmcgroup.com marketing@gmmcgroup. com

Lancing products for capillary blood testing, such as lancing devices, general lancets and safety lancets.

Goldsite Diagnostics

China • Shenzhen Tel: (86) 755-2689-0807 en.goldsite.com.cn sales@goldsite.com.cn

Product range includes automated analyzers for specific protein tests, chemiluminescence, biochemistry, hematology, POCT instruments, and rapid test kit solutions.

Gold Standard Diagnostics

Germany • Dietzenbach Tel: (49) 6074 236980 clinical.goldstandarddiagnostics.com info.frankfurt@eu.goldstandarddiagnostics.com

Provides automated platforms and a broad menu of tests in the fields of virology, bacteriology, parasitology, mycology, hormones, autoimmune diseases, and more recently, in oncology.

Gongdong Medical Technology

China • Taizhou Tel: (86) 576-8411-5678 en.gongdong.com info@gongdong.com

Disposable medical and lab consumables.

GC Medical Science Corp.

Korea • Gyeonggi-do Tel: (82) 31-267-8458 greencrossms.com gcms.overseas@gccorp. com

Provides innovative POCT

devices for professional healthcare and daily health management. These advanced devices are perfectly suited for hospitals, laboratories, and chronic disease centers, offering fast and precise measurements of key health indicators like glucose, lipids, hemoglobin and HbA1c.

Greiner Bio-One International

Austria • Kremsmunster Tel: (43) 7583-6791-0 gbo.com office@at.gbo.com

The Preanalytics division offers specimen collection systems for blood and urine. The Bioscience division offers products including pipettes, PCR plates, reaction tubes, analyzer cups, and cell separation media.

Grifols International

Spain • Barcelona Tel: (34) 935-712-200 diagnostic.grifols.com

Diagnostic division develops instrumentation and reagents, specializing in transfusion medicine, immunology and hemostasis.

Haier Biomedical

China • Qingdao Tel: (86) 532-889-35593 haiermedical.com inquiry@haierbiomedical. com

Low temperature storage equipment for biomedical samples, with products offering complete cold chain solutions for biological sample banks, blood safety, vaccines, and reagent safety.

Hamilton Company

USA • Reno, NV Tel: (1) 775-858-3000 hamiltoncompany.com sales@hamiltoncompany. com

Specializes in automated liquid handling solutions and automated sample management systems, in addition to other laboratory products such as HPLC columns, pipettes, needles and syringes.

Hardy Diagnostics

USA • Santa Maria, CA Tel: (1) 805-346-2766 hardydiagnostics.com Sales@HardyDiagnostics. com

Manufactures over 3,500 different products used in the microbiology laboratory. Products include prepared culture media, dehydrated culture media, antimicrobial susceptibility testing, microbiology test kits, reagents and stains, specimen collection and transport, and more.

HEALES

China • Shenzhen Tel: (86) 1368-6871-802 heales.cn sales@heales.cn

Clinical diagnosis products including liquid handling

systems, microplate washers and readers, specific protein analysis systems, nucleic acid extraction, and reagents.

Healgen Scientific USA • Houston, TX Tel: (1) 713-733-8088 healgen.com

Testing platforms include rapid testing, molecular diagnostics, and multiplex flow cytometry, offering solutions in the areas of infectious diseases, toxicology, pregnancy and fertility, urinalysis, oncology, and cardiovascular conditions.

Hecht - Assistent Germany • Sondheim vor der Rhön Tel: (49) 9779-808-0 assistent.eu info@assistent.eu

Products for blood tests and urine analysis, microscopic and staining utensils, liquid handling, water treatment, measuring glass instruments, as well as general lab apparatus, and hydrometers and thermometers.

Helena Laboratories

USA • Beaumont, TX Tel: (1) 409-842-3714 helena.com helena@helena.com

Products include electrophoresis analyzers, densitometers, electrophoresis supplies, hemostasis reagents and instruments, immunology and protein diagnostics, disposable laboratory plasticware, test kits for fecal occult blood, and other products.

Helmer Scientific USA • Noblesville, IN Tel: (1) 317-773-9073 helmerinc.com sales@helmerinc.com

Lab equipment and temperature-controlled products. Blood bank products include refrigerators, freezers, platelet storage systems, and plasma thawing systems.

HEMCO Corporation

USA • Independence, MO Tel: (1) 816-796-2900 hemcocorp.com info@hemcocorp.com

Basic laboratory equipment featuring the UniFlow series of fume hoods constructed of molded chemical resistant, flame retardant, non-metallic composite resin. Cabinets, work surfaces, ventilation, and accessories are offered to meet requirements.

HemoCue

Sweden • Angelholm Tel: (46) 77-570-02-10 hemocue.com

info@hemocue.se

Products for point-of-care testing. The company offers POC tests for glucose, urine albumin and HbA1c as well as total and differential white blood cell count.

Hepy

Poland • Warsaw

Tel: (48) 789-473-586

order@hepytest.com hepyureasetest.pl

Focuses on providing health service providers with good quality tests that enable accurate and quick diagnosis. The company has developed an ultra-fast dry urease test for detecting Helicobacter pylori that is trusted by many renowned doctors and used in many countries around the world.

Hettich

Germany • Tuttlingen

Tel: (49) 7461-705-0

hettichlab.com

info@hettichlab.com

Complete line of centrifuges and incubators. Centrifuge varieties include microliter, hematocrit, benchtop, floor-standing models, robotic centrifuges and cell washer.

HiMedia Laboratories

India • Thane

Tel: (91) 22-6147-1919 himedialabs.com

info@himedialabs.com

High quality culture media for microbiology, and offers a complete range of chromogenic and HiVeg media products.

Hipro Biotechnology

China • Shijiazhuang

Tel: (86) 400-0191-606 www.hipro.us hipro@hipro.us

Product range covers automated immunoassay analyzers, semi-automated analyzers, and other POC instrument as well as a wide range of diagnostic reagents.

Hologic

USA • Marlborough, MA

Tel: (1) 508-263-2900 hologic.com salessupport@hologic.com

Products for medical imaging, surgery, and diagnostics. The company develops innovative cytology and molecular testing solutions with its broad menu of Aptima assays, Panther Fusion assays and Panther scalable solutions for lab automation.

Horiba Medical

France • Montpellier

Tel: (33) 4-67-14-15-16 horiba.com/medical

Comprehensive solutions for in vitro diagnostic in hematology, hemostasis and clinical chemistry, including automated analyzers, reagents and consumables.

Horron XLH

Medical

China • Shenzhen

Tel: (86) 755-2685-5736 horron.com export@horron.com

In-vitro diagnostic devices and reagents, including analyzers for electrolytes, specific proteins, ESR, immunoassay, and clinical chemistry.

HTL

Poland • Warsaw Tel: (48) 22-492-19-00 htl.com.pl htlcs@corning.com

Liquid handling equipment including variable-volume pipettes, fixed-volume pipettes, electronic pipetting controllers, and manual dispensers

Human Diagnostics

Germany • Wiesbaden

Tel: (49) 6122-9988-0 human.de info@human.de

Broad portfolio of in vitro diagnostic products covering the whole spectrum of clinical routine laboratory work. Products include instruments, equipment, and reagents for clinical chemistry, POC testing, immunology, microbiology, hematology, and coagulation.

Humasis

Korea • Gunpo Tel: (82) 31-8085-6200 humasis.com marketing@humasis.com

POC testing with rapid test kits for cardiac markers, fertility hormones, infectious diseases, and cancer markers.

Hycor Biomedical

USA • Garden Grove, CA Tel: (31) 20-899-4280 hycorbiomedical.com info@hycorbiomedical.com

Systems and testing products for in-vitro allergy and autoimmune disorders, including a new generation fully-automated system for routine allergy diagnostics.

HyTest

Finland • Turku Tel: (358) 2-512-0900 hytest.fi hytest@hytest.fi

High-quality immunological reagents in areas such as cardiac markers, infectious diseases, blood coagulation, anemia and inflammation. A leading provider of reagents for troponin I immunoassays, as well as for certain infectious diseases.

i-Sens

Korea • Seoul Tel: (82) 70-7093-9609 i-sens.com inquiry@i-sens.com

Specializes in blood glucose testing as well as a range of POCT devices (HbA1c, Blood Gas, Electrolyte, PT/INR Analyzer) for diabetes monitoring, electrolyte and blood gas testing, and coagulation testing.

IBL- America

USA • Minneapolis, MN Tel: (1) 763-780-2955 ibl-america.com info@ibl-america.com

High-quality laboratory reagent assays for research and clinical testing in various areas including autoimmunity, endocrinology, infectious disease, oncology and neuroscience. Products include ELISA kits, RIA kits, chemiluminescent diagnostic and research tools, antibodies and proteins.

Illumina

USA • San Diego, CA

Tel: (1) 858-202-4566 illumina.com info@illumina.com

NGS sequencing platforms and array-based systems for genetic analysis, including IVD solutions for reproductive health, oncology, and genetic diseases.

Immundiagnostik

Germany • Bensheim Tel: (49) 6251-701-900 immundiagnostik.com contact@immundiagnostik.com

Novel immunoassays and analytical tools focused in prevention, differential diagnosis and ther-

apy monitoring in the areas of gastroenterology, cardiovascular diseases, disorders of the skeletal system and oxidative stress.

Immuno Concepts

USA • Sacramento, CA Tel: (1) 916-363-2649 immunoconcepts.com

Diagnostic test kits for autoimmune diseases. Products include slides, ELISA assays, automated sample processors and automated IFA system.

Immunodiagnostic Systems

UK • Boldon, Tyne and Wear Tel: (44) 191-519-0660 idsplc.com salessupport.uk@idsplc.com

The company’s immunoassay portfolio combines an endocrinology specialty testing menu and assay panels in complementary fields.

LabMedica 400

InBios International

USA • Seattle, WA (1) 206-344-5821 inbios.com inquiries@inbios.com

Diagnostic tests for emerging infectious diseases and biothreats. Products include a wide range of high-performing ELISA kits and rapid immunoassays for dengue, leishmaniasis, chagas, Covid-19, and others.

IncreCare

China • Shenzhen Tel: (86) 199-61289678 sales@increcare.com increcare.com

Develops and produces a series of advanced chemiluminescence instruments. Products also include fluo-

rescent immunoassay equipment, and a serious of other innovative in-vitro diagnostic solutions.

SEE AD ON PAGE 15 s InTec Products China • Xiamen Tel: (86) 592-680-7188 intecasi.com intecproducts@asintec.com In vitro diagnostic reagents that focus on infectious disease tests, ELISA, PCR methods, drugs of abuse, fertility and tumor marker. Recently added to the product line is a diabetes monitoring system and a rapid test reader.

SEE AD ON PAGE 19 s

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Integra Biosciences

USA • Hudson, NH

Tel: (1) 603-578-5800

integra-biosciences.com

Solutions for pipetting and media preparation. Products include electronic pipettes, pipetting robots, pipette controllers, pipette tips and reservoirs.

Invetech

Australia • Melbourne

Tel: (61) 3 9192 6000 invetechgroup.com info@invetech.com.au

Products, instruments, and custom automation services to in vitro diagnostics, medical devices, life sciences, drug discovery, and pharmaceutical companies.

Iwaki Pumps

Japan • Tokyo Tel: (81) 3-3254-2935 iwakipumps.jp

High-purity metering pumps, chemical delivery pumps, recirculation pumps and nonmetallic magnetic drive centrifugal pumps and systems.

JEOL

Japan • Tokyo Tel: (81) 42 5422303 jeol.co.jp

Scientific and metrology instruments. In the area of medical diagnostics, provides a line of automated clinical chemistry analyzers.

JOKOH

Japan • Tokyo Tel: (81) 44-811-9211 jokoh.com

Devices including electrolyte analyzers, ESR anaylzer and POCT reader. The company’s product portfolio also includes high pressure homogenizers, and a liquid-based cytology cell processor.

JP Selecta

Spain • Barcelona Tel: (34) 937 700 877 grupo-selecta.com selecta@jpselecta.es

Products that include autoclaves, blood bank cabinets, baths, centrifuges, incubators, blood collection tubes, pipettes, and ESR systems, among others.

Kabe Labortechnik

Germany • Numbrecht-Elsenroth Tel: (49) 22-93-9132-0 kabe-labortechnik.de info@kabe-labortechnik.de

Products include treated and untreated test tubes for blood, urine and feces examinations, blood collection systems for venous and capillary blood, mixers for blood samples, devices for blood sugar determination and for determination of blood sedimentation rate.

Kamiya Biomedical

USA • Seattle, WA

Tel: (1) 206-575-8068 k-assay.com info@k-assay.com

Over 40 immunoassay reagents for chemistry analyzers. The reagents are

available for lipid, diabetes, stroke, anemia, allergy, inflammation, nutrition, kidney, and cardiac testing.

Kangrun Biotech

China • Guangzhou Tel: (86) 020 28662744 kangrun.com.cn sale@kangrun.com.cn

Specializes in immunoassay solutions with automated instruments for CLIA, immunoblot and IFA analysis.

Kartell Labware

Italy • Milan Tel: (39) 2-900-121 kartelllabware.com labware@kartell.it

Wide range of lightweight, ergonomic products for the laboratory market including plasticware, disposables, and a range of liquid handling options.

Kehua Bioengineering

China • Shanghai Tel: (86)-21-6495-0625 skhb.com international@skhb.com

Reagents, automatic clinical chemistry analyzers, microplate readers and washers, electrolyte analyzers, decapping centrifuges, and vacuum blood collection tubes.

Kementec

Denmark • Taastrup Tel: (45) 39-27-1771 kementec.com support@kementec.com Superior, technology-enhanced components for colorimetric- and chemiluminescent-based immunoassays.

KH Medical

Korea • Pyeongtaek (82) 31-647-0109 khmedical.co.kr adamhong@khmedical. co.kr

Diagnostic products include a series of molecular platforms for automated nucleic acid extraction and PCR, DNA/RNA extraction kits, and immunoassay rapid test kits for infectious diseases.

Labcon

USA • Petaluma, CA Tel: (1) 707-766-2100 labcon.com info@labcon.com

Laboratory consumables in the areas of liquid handling, centrifugation, clinical chemistry, PCR, cultures, point-ofcare, and sample transport.

LABEX Reagens

Sweden • Helsingborg Tel: (46) 42-32-40-00 labexreagens.com reagents@labex.com

Specializes in reagents and controls for hematology instruments.

Labline

Equipments

India • Vadodara Tel: (91) 265-263-2148 lablineindia.com mail@lablineindia.com

Brushless centrifuges, needle destroyers, blood mix-

ers, centrifuges, differential blood cell counters, vortex mixers, dry bath incubators, hematocrit digital centrifuges and roller mixers.

Labnovation

Technologies

China • Shenzhen Tel: (86) 755-8636-8328 labnovation.com export@labnovation.com

Product range includes HPLC HbA1c analyzers, POC HbA1c analyzer, rapid test reader, rapid test kits for infectious diseases, and reagents for hematology and clinical chemistry devices.

Labtest

Brazil • Lagoa Santa Tel: (55) 31-3689-6900 labtest.com.br labtest@labtest.com.br IVD reagents and diagnostic equipment for laboratories of all sizes, including several lines of analyzers for biochemistry and turbidimetry as well as hematology

LabTurbo Biotech

Taiwan • Taipei City Tel: (886) 2-2889-1136 labturbo.com.tw info@labturbo.com.tw

Automation of DNA and RNA applications, focusing on the technologies and innovations for sample-to-result DNA/RNA testing systems, fully automated DNA/RNA extraction systems, qPCR testing kits (for COVID-19), extraction kits, and 96-well and 384-well liquid-handling systems.

Lampire Biological Laboratories

USA • Pipersville, PA Tel: (1) 215-795-2838 lampire.com info@lampire.com

Custom polyclonal and monoclonal antibody development, secondary antibodies, IgGs, BSA, animal blood and tissue products, human serums and plasmas, cell media and cell culture bags.

Landwind Medical

China • Shenzhen Tel: (86) 755-8393-5015 landwindmedical.com

sales@landwindmedical.com

Complete range of chemistry analyzers, hematology analyzers, biochemistry reagents, and COVID-19 detection solutions.

LDN Labor Diagnostika Nord

Germany • Nordhorn Tel: (49) 5921-8197-0 ldn.de info@ldn.de

Immunodiagnostic assays for the research and clinical laboratory, offering a comprehensive endocrinological panel, especially also for niche parameters.

Lee Company, The USA • Westbrook, CT Tel: (1) 860-399-6281 theleeco.com inquiry@theleeco.com

Miniature fluid control com-

ponents for automated liquid handling in medical and scientific instrumentation, analytical/clinical chemistry, and medical disposable applications.

Leica Microsystems

Germany • Wetzlar

Tel: (49) 64-41-29-4099 leica-microsystems.com

Optical solutions based on microscopes and related instruments.

LGC Clinical Diagnostics

Ireland • Ballina, Tipperary Tel: (353) 61-525-700 lgcclinicaldiagnostics.com CDx-Sales@lgcgroup.com

Provides Quality Management Tools that are liquid, ready-to-use, and deliver efficiencies, allowing laboratories to report patient results with confidence.

Product brands include: Multichem®, ACCURUN®, Detectabuse®, Kova Liqua-Trol®, Stat-Skreen® and VALIDATE®

LifeReal Biotechnology

China • Hangzhou Tel: (86) 571-87118973702 en.lifereal.com.cn overseas1@lifereal.com.cn

Products for the life science and clinical diagnostic fields that include an automatic integrated gene detection system and POC testing for COVID-19 and other infectious diseases.

Liferiver Biotech

USA • La Jolla, CA Tel: (1) 858 3526520 liferiverbiotech.com usa@liferiverbiotech.com

Specializes in nucleic acid detection products, offering 400+ real time PCR tests covering most infectious diseases as well as various instruments including fully automated sample-to-result systems.

LifeSign

USA • Skillman, NJ Tel: (1) 732-246-3366 lifesignmed.com info@lifesignmed.com

Point-of-care testing solutions for the detection of medical conditions and illnesses that include cardiac markers, infectious disease, women’s health, abused drugs, urinary tract infections, and GI disorders.

Lifotronic Technology

China • Shenzhen

Tel: (86)-755-2901-6066 en.lifotronic.com inter@lifotronic.com

A range of in vitro diag-

nostic products include hematology analyzers, HPLC systems, eCLIA systems, PCR analyzers, HbA1c Analyzers, immunofluorescence anaylzers and rapid test kits.

Linear Chemicals

Spain • Barcelona Tel: (34) 934 694 990 linear.es info@linear.es

In vitro diagnostic (IVD) instruments and reagents, and accessories for clinical laboratory. The company exports all over the world: the brands Cromatest, Clonatest, Plus-Sed and LiNEAR are distributed in 125 countries.

Liofilchem

Italy • Roseto degli Abruzzi Tel: (39) 085-893-0745 liofilchem.com liofilchem@liofilchem.net

Wide range of products for microbiology applications in the areas of AMR management, transport media, culture media, blood culture, urine analysis, and more.

Lituo Biotechnolgy

China • Zhuhai Tel: (86) 756-8639521 www.lituo.com.cn market@lituo.com.cn

Diagnostic reagents and instruments specializing in the areas of microbiological diagnosis, vaginitis detection, cervical cancer screening stool routine examination, blood culture, immunoassay, and rapid testing for COVID-19.

Logical Biological

UK • Kent Tel: 44 (0)1304 799747 info@logicalbiological.com logicalbiological.com

Provides high-quality biospecimens for diseased and healthy human serum, plasma, swabs, saliva and other biological samples, all of which are essential components in IVD tests.. The company supplies material either in bulk volumes or as small clinical samples.

LP Italiana

Italy • Milan Tel: (39) 02-3933-061 lpitaliana.com info@lpitaliana.com

Disposable products for clinical chemistry, hematology, serology, microbiology and bacteriology.

Lumigenix

China • Suzhou (86) 0512-80988088 lumigenex.com lumi@lumigenex.com

Immunoassay POCT readers and diagnostic kits for detection of diseases in the areas of cardiology, inflammation, diabetes, women’s health, and others. Also offers dry chemistry analyzers and reagents to manage chronic diseases by measuring lipids, glucose, creatinine and uric acid.

LumiQuick Diagnostics, Inc.

USA • Santa Clara, CA Tel: (1) 408-855-0061 lumiquick.com

sales@lumiquick.com

Develops, manufactures, and markets point of care tests and other immunoassay kits for the world-wide In vitro diagnostic market. Offers extensive product lines of rapid tests, ELISA, CLIA and raw materials. Provides test for detection of infectious diseases, cardiac markers, cancer markers, drugs of abuse, fertility hormones and other disease markers.

LW Scientific USA • Lawrenceville, GA Tel: (1) 770-270-1394 lwscientific.com

info@lwscientific.com

Microscopes, centrifuges, and general lab equipment, for applications in hematology, pathology, cytology, and infectious diseases.

Maccura Biotechnology

China • Chengdu Tel: (86) 028-8173-1888 maccura.com

export@maccura.com

Analyzers, reagents and equipment for applications in clinical biochemistry, chemiluminescent immunoassay, hematology, hemostasis, molecular diagnostics, point of care, and laboratory automation solutions.

Macherey-Nagel

Germany • Düren Tel: (49) 2421-9690 mn-net.com

sales@mn-net.com

pH papers, medical diagnostic test strips, and other such related paper products for rapid tests, chromatography, and bioanalysis. The company offers 96-well plates, cartridges, test strips, urine analysis, pH-fix, and medical diagnostics for rapid tests.

Macro & Micro Test

China • Rudong County, Jiangsu Tel: (86) 0512-8816-6813 mmtest.com

sales@hongweitest.com

Molecular diagnosis, immunology, POCT and other technology platforms, with product lines covering infectious disease prevention and control, reproductive health testing, genetic disease testing, personalized drug gene testing, COVID-19 detection, and others.

Magnus Opto Systems

India • New Delhi Tel: (91)-9717-710061 magnusopto.com

info@magnusopto.com

Microscopes and microscope optics for the clinical laboratory market.

Mast Group

UK • Bootle, Merseyside Tel: (44) 151-933-7277

mast-group.com

sales@mastgrp.com

IVD kits, reagents, and equipment for the clinical market with an emphasis on microbiology.

Mawi DNA Technologies

USA • Pleasanton, CA (1) 510-256-5186 mawidna.com info@mawidna.com

Unique biosample collection technologies, enabling universal sample collection from any population segment and allowing samples to be transported and stored at room temperature.

Mayo Clinic Laboratories

USA • Rochester, MN

Tel: (1) 507-266-5700 mayocliniclabs.com mliintl@mayo.edu

specimen collection devices, swabs and laboratory consumables.

Medicon

Greece • Athens Tel: (30) 210-6606000 mediconsa.com medicon@mediconsa.com

Diagnostic reagents, the production of laboratory information software, and the import and distribution of in vitro diagnostics and automated analytical systems.

Medix Biochemica

Finland • Espoo Tel: (358) 9-547-680 medixbiochemica.com medix@medixbiochemica. com

Monoclonal antibodies, antibody services and recombinant antigens for the IVD

PCR, qPCR and sequencing, and analytical chemistry techniques including liquid chromatography followed by mass spectrometry (LC-MS).

Meridian Bioscience

USA • Cincinnati, OH

Tel: (1) 513-271-3700

meridianbioscience com mbi@meridianbioscience. com

Diagnostic test kits, purified reagents and biopharmaceutical-enabling technologies for the early diagnosis and treatment of common medical conditions. Its products are ideal for hospitals, reference laboratories, research centers, physician offices and diagnostics manufacturers.

Micro Lab Instruments

info@monobind.com

The company’s AccuBind® ELISA and AccuLite® CLIA systems are offered in the IVD areas of thyroid, fertility & steroids, tumor & cardiac markers, anemia, bone metabolism, diabetes, neonatal & prenatal, allergy and infectious diseases.

Monocent

USA • Chatsworth, CA Tel: (1) 424-310-0777 monocent.com

info@monocent.com

An extensive test system portfolio that includes ELISA assays, rapid tests, chemiluminescence assays, serology tests, and IFA test. Offers instrumentation including microplate washers and readers, automated ELISA/CLIA analyzer.

Moss USA • Pasadena, MD

Tel: (1) 410-768-3442

mossbio.com info@mossbio.com

Liquid stable immunoassay reagents, including substrates and conjugates, used in diagnostic testing applications. All products are produced in bulk and are stable for 30-48 months.

MP Biomedical

USA • Irvine, CA

Tel: (1) 949-833-2500

mpbio.com custserv@mpbio.com

Wide range of in vitro diagnostic solutions in the areas of autoimmune, biogenic amines, cardiac markers, endocrinology, infectious diseases, mo-

www.espcongress.org

lecular diagnostics, newborn screening, and tumor markers.

MPW Med. Instruments

Poland • Warsaw Tel: (48) 22-610-56-21 mpw.pl

mpw@mpw.pl

Wide range of medical and laboratory centrifuges including universal and special types, low- and highspeed, refrigerated or refrigerated and heated.

NanoEntek

Korea • Seoul Tel: (82) 2-6220-7728

nanoentek.com

sales@nanoentek.com

Specializes in the fields of biomedical engineering, bio-MEMS (Micro-Electro-Mechanical Systems),

LabMedica 400

electronics, chemistry, and optics, and have developed innovative products for life science research and point-of-care diagnostics.

NanoHelix

Korea • Daejeon

Tel: (82) 42-867-9055

info@nanohelix.net nanohelix.net

Provides high-quality molecular biological reagents and raw materials for molecular diagnostics. Also specialize in the customized production of enzymes for molecular diagnostics and offer high-quality, specialized products.

Neogen

USA • Lansing, MI

Tel: (44) 161-820-3833 neogen.com inform@neogen.com

Line of products for life science research, forensic toxicology and IVD manufacturing.

New England Biolabs

USA • Ipswich, MA Tel: (1) 978-927-5054 neb.com info@neb.com

Discovery and production of enzymes for molecular biology applications. The company’s diagnostic products include a large selection of products for PCR, qPCR, RT-qPCR and isothermal amplification.

NG Biotech

France • Guipry Tel: (33) 09-71-70-53-10 ngbiotech.com contact@ngbiotech.com

The company’s proprietary patented immunoassay platform enables the development of quantitative and multiplex POC diagnostics and can be adapted to detect or monitor any kind of antibody, antigen, pathogen, parasite, hormone, or drug.

Nihon Kohden

Japan • Tokyo

Tel: (81) 3-5996-8036 nihonkohden.com

Major product line for clinical diagnostics includes both automatic and semiautomatic hematology analyzers.

Nikon Instruments

USA • Melville, NY

Tel: (1) 631-547-8500 microscope.healthcare. nikon.com

Optical and digital imaging technology for biomedical applications. Produces industry-leading microscope systems for clinical pathology including digital pathology and remote slide viewing and sharing.

Nittobo America

USA • Murrieta, CA

Tel: (1) 951-677-5629

nittobous.com

sales@nittobous.com

Bulk polyclonal antisera and

complementary products, and bulk raw materials for immunodiagnostic assay manufacturers.

Nordic Biomarker

Sweden • Umea

Tel: (46) 90-71-86-01 nordicbiomarker.com info@nordicbiomarker.com

Advanced reagents, calibrators and controls for coagulation, offering products used for a wide range of routine and specialty tests.

Noul

Yongin • Korea Tel: (82) 31-308-6310 noul.kr

Next generation point-of-care blood testing platform for resource-limited medical facilities, clinics, and local hospitals, offering a diagnostic solution for malaria, cervical cancer, blood cell morphology, among others.

Nova Biomedical

USA • Waltham, MA Tel: (1) 781-894-0800 novabio.us info@novabio.com

Develops and manufactures whole blood, point-of-care and critical care analyzers. Product applications include usage in the central laboratory, emergency department, surgery, critical care area, or respiratory care area.

NuAire

USA • Plymouth, MN Tel: (1) 763-553-1270 nuaire.com

Biological safety cabinets, CO2 water-jacketed incubators, laminar air flow equipment, ultra-low temperature freezers, and complementary products and systems.

Nüve

Turkey • Ankara Tel: (90) 312-399-2830 nuve.com.tr sales@nuve.com.tr

Wide range of laboratory equipment including incubators, deep freezers, dry heat sterilizers, ovens, centrifuges, water baths and water distillers, blood bank refrigerators, safety cabinets, and bench-top steam sterilizers.

Oasis Diagnostics

USA • Vancouver, WA Tel: (1) 360-546-1563 4saliva.com info@4saliva.com

Focuses on non-invasive saliva-based technology for rapid testing, sample collection, and molecular diagnostics (DNA, RNA and proteins).

Omega Bio-tek

USA • Norcross, GA Tel: (1) 770-931-8400 omegabiotek.com info@omegabiotek.com

DNA/RNA purification kits for clinical, biotechnology, and genomics research. With a diversified product portfolio for low-throughout to

high-throughput purification, the company’s kits purify high-quality nucleic acids from a wide variety of samples.

Operon

Spain • Zaragoza Tel: (34) 976-50-3597 operon.es sales@operon.es

Immuno and molecular in vitro diagnostic products including lateral flow tests, and molecular tests for clinical diagnostics.

OraSure Technologies

USA • Bethlehem, PA Tel: (1) 610-882-1820 orasure.com customercare@orasure. com

Fluid diagnostic and collection devices. Products include oral fluid testing solutions for drugs of abuse and rapid assays for HIV, HCV, COVID-19, Ebola, and influenza.

Owen Mumford

UK • Woodstock, Oxfordshire Tel: (44) 1993-812021 owenmumford.com info@owenmumford.com

Specializes in treatment and diagnosis of chronic diseases such as rheumatoid arthritis, diabetes and multiple sclerosis. Offers products for specimen collection and POC testing.

Oxford Nanopore

UK • Oxford (44) 0-845-034-7900 sales@nanoporetech.com nanoporetech.com

Specializes in next generation DNA/RNA nanopore sequencing devices, ranging from the, benchtop and large-scale models.

Paul Marienfeld

Germany • LaudaKönigshofen Tel: (49) 0-9343-6270-0 marienfeld-superior.com info@ marienfeld-superior.com

Comprehensive range of laboratory glassware including microscope slides, cover glass, counting chambers, capillary tubes, lab containers, and volumetric glassware.

Perlong Medical Equipment

China • Nanjing Tel: (86) 25-5263-5350 perlong-china.com perlong@perlong-china. com

Clinical laboratory equipment and reagents including semi-automated and automated analyzers for biochemistry, hematology, blood coagulation, urine analysis, ESR, electrolytes, and more.

PHC Europe

Netherlands • Etten Leur Tel: (31) 765-433-833 phchd.com/eu/phceu biomedical.nl@eu.phchd.

com

Specializes in products for lab preservation, incubation, sterilization, and cell analysis with products such as ultra-low freezers, biomedical freezers, CO2 incubators, multigas incubators, among others.

Polymedco

USA • Cortlandt Manor, NY Tel: (1) 914-739-5400 polymedco.com info@polymedco.com

Diagnostic test kits and devices for non-invasive fecal immunochemical testing and bladder cancer monitoring.

Porex

USA • Fairburn, GA Tel: (1) 770-964-1421 porex.com info.porex.emea@ filtrationgroup.com

Porous plastic products for use in numerous applications that involve filtering, venting, wicking, diffusion, fluid and gas control, media support, and many other related applications.

Precision Biologic

Canada • Dartmouth, NS Tel: (1) 902-468-6422 precisionbiologic.com

High quality frozen diagnostic products for hemostasis including controls and specialty plasmas, factor assays and integrated test kits. With the addition of Affinity Biologicals, the company also offers an extensive line of antibodies to coagulation and hemostasis related proteins, conjugates, antibody pairs for immunoassay.

Preventis

Germany • Bensheim Tel: (49) 6251-707-110 preventis.com info@preventis.com

Point-of-care diagnostics, preventive medicine and therapy monitoring. Tests can be evaluated quickly and quantitatively with a smartphone app, enabling effective practice management and possibilities for telemedicine solutions.

Prokan

Electronics

China • Shenzhen Tel: (86)-755-26955166 prokanmed.com info@prokanmed.com

Selection of automatic hematology analyzers and hematology reagents, as well as a line of automatic chemistry analyzers.

Pro-Lab

Diagnostics

Canada • Richmond Hill, ON Tel: (1) 905-731-0300 pro-lab.com support@pro-lab.com

Immunodiagnostic reagents specializing in clinical microbiology, with products including a line of latex agglutination, organism storage and retrieval system, and a variety of general microbiology products.

Protia

Korea • Seoul Tel: (82) 2-6968-5278 protia.co.kr protia@protia.co.kr

Novel protein targets for disease prediction, early diagnosis, and development of new medicines. Developed unique in vitro diagnosis products such as allergy diagnosis kits, food intolerance tests, immune-system monitoring kit and next-generation pregnancy diagnosis kits.

Puritan Medical Products

USA • Guilford, ME Tel: (1) 207-876-3311 puritanmedproducts.com sales@ puritanmedproducts.com

Tipped applicators and transport devices for specimen collection. A broad line of swabs includes fiber, foam, and Puritan’s patented PurFlock Ultra and HydraFlock flock swabs. The company also offers a complete line of media transport systems for the collection of bacteria and viruses.

Q-Line Biotech

India • Lucknow Tel: (91) 0522-2433023 www.qlinebiotech.com info@qlinebiotech.com

In vitro diagnostic instruments, reagents and kits for biochemistry, immunology and molecular diagnostics.

Qiagen

Germany • Hilden

Tel: (49) 2-103-29-12000 qiagen.com

Sample and assay technologies used to isolate and process DNA, RNA, and proteins from biological samples with a product portfolio that encompasses consumable kits, instruments, and bioinformatics.

Quanterix

USA • Billerica, MA, (1) 617-539-8375 quanterix.com sales@quanterix.com

Platforms for ultrasensitive biomarker detection based on SIMOA technology targeting the areas of cardiology, infectious disease, inflammation, neurology, and oncology.

Quantimetrix

USA • Redondo Beach, CA Tel: (1) 310-536-0006 quantimetrix.com sales@quantimetrix.com

Ready-to-use liquid laboratory quality control and testing products. Its liquid quality control products include urinalysis, general and special chemistry, and diabetes; liquid diagnostic assays; and OEM and contract manufacturing services.

QuidelOrtho

USA • San Diego, CA

Tel: (1) 858-552-1100 quidelortho.com customerservice@quidel.

com

Rapid diagnostic tests that focus on infectious diseases, reproductive health, and molecular diagnostics. An expanded product portfolio includes systems for clinical chemistry, immunoassays, and additional solutions for automation and workflow management.

Quimica Clinica Aplicada

Spain • Amposta Tel: (34) 977-70-62-30 qca.es export@qca.es IVD reagents for use in biochemistry, immunology, hemostasis, microbiology, histopathology, and hematology applications.

R-Biopharm

Germany • Darmstadt Tel: (49) 6151-8102-0 r-biopharm.com info@r-biopharm.de Enzyme immunoassays for the detection of infectious diseases. The product line contains test systems in the field of stool diagnostics, infectious disease, serology, and allergy testing.

Radiometer

Medical

Denmark • Copenhagen Tel: (45) 38-27-38-27 radiometer.com radiometer@radiometer.dk

Products and solutions for blood sampling, blood gas analysis, transcutaneous monitoring, immunoassay testing and related IT management systems.

RAL Técnica para el Laboratorio

Spain • Barcelona Tel: (34) 93 480 80 47 ral-sa.com ral@ral-sa.com

Equipment for in vitro diagnosis in the clinical laboratory, including hematology analyzers, coagulation analyzers, biochemistry analyzers, urine analyzers, ESR analyzers and electrolyte analyzers, among others.

Randox Laboratories

UK • Crumlin, County Antrim Tel: (44) 0-28-9442-2413 randox.com

marketing@randox.com

Diagnostic products including biochemistry, immunoassay & molecular analyzers in addition to first and third-party reagents. The comprehensive Randox Quality Control package comprises third party controls, inter-laboratory data management and large global EQA scheme.

Ratiolab

Germany • Dreieich Tel: (49) 0-6103-30025-0 ratiolab.com

info@ratiolab.com

High-quality plastic products such as pipette tips, cuvettes, and micro test plates, as well as a variety of liquid handling equipment and analyzers under its Slamed brand.

Rayto Life and Analytical Sciences

China • Shenzhen

Tel: (86) 755-8883-2350 rayto.com

info@rayto.com.cn

Chemistry analyzers, ELISA readers and washers, coagulation analyzers, hematology analyzers and urine analyzers.

RBC Bioscience

Taiwan • New Taipei City (886) 2-8912-1200 rbcbioscience.com

info@rbcbioscience.com

Specializes in nucleic acid extraction technologies, offering scalable solutions for diagnostics and research.

Reagena

Finland • Toivala Tel: (358) 10-5045-200 reagena.com info@reagena.com

Infectious disease diagnostics specializing in zoonotic infections and liquid-based solutions, also reagents for life sciences.

RealMind Biotech

China • Nanjing Tel: (86) 025-69579511 realmindbio.com

sales@realmindbio.com

A wide range of CLIA reagents including the routine panels like thyroid, fertility, tumor markers, cardiac markers, and more, as well as automated CLIA analyzers for POCT.

Response Biomedical

Canada • Vancouver, BC Tel: (1) 604-219-6119 responsebio.com customersupport@responsebio.com

The company’s rapid diagnostics platform delivers lab quality performance for efficient patient management in acute care settings, providing acute care testing with a wide range of marker including troponin I, CK-MB, myoglobin, NT-proBNP, D-dimer and procalcitonin.

Revvity

USA • Waltham, MA Tel: (1) 781-663-6900 www.revvity.com

Offers diagnostic solutions for maternal and fetal health, newborn screening, infectious disease, rapid testing, as well as a range of laboratory instruments and consumables.

RNA Medical

USA • Devens, MA

Tel: (1) 978-772-9070

rnamedical.com

rnasales@rnamedical.com

Quality control materials and related products for blood gas, critical blood analyte, and diabetes care applications. The product line includes daily QC materials, calibration verification and linearity products, and glass capillary blood collection tubes.

Roche Diagnostics

Switzerland • Basel Tel: (41) 61-688-1111 roche.com

Wide range of in vitro diagnostic systems, instruments, reagents, and tests covering the main product areas of clinical chemistry and immunochemistry, molecular diagnostics, anatomic pathology, and point of care.

SA Scientific

USA • San Antonio, TX Tel: (1) 210-699-8800 sascientific.com sales@sascientific.com

Rapid diagnostic tests for infectious and bacterial diseases, as well as food microbiology, veterinary testing, and environmental testing.

Sakura Finetek Europe

Netherlands • Alphen aan den Rijn Tel: (31) 88-592-00-00 sakura.eu info@sakura.eu

Integrated solutions for anatomic pathology to advance cancer diagnostics. Tissue-Tek brand offers tissue processors, automatic microtomes, and slide stainers.

Saladax Biochemical

USA • Bethlehem, PA Tel: (1) 610-419-6731 hello@saladax.com saladax.com

Provides psychiatrists and oncologists with essential information for timely treatment decisions. By measuring a patient’s blood levels, healthcare professionals can ensure the correct drug dosage for each individual.

Salimetrics

USA • State College, PA Tel: (1) 814-234-2617 salimetrics.com support@salimetrics.com

Provide researchers, analytical and functional testing laboratories, and the immunodiagnostic industry with innovative salivary immunoassay products and services.

Sansure Biotech

China • Changsha Tel: (86) 731-8888-31766116

sansure.com.cn info@sansure.com.cn

Provides diagnostic reagents, nucleic acid diagnostic instruments, complete lab solutions and lab chain services.

Sarstedt

Germany • Nümbrecht

Tel: (49) 2293-3050 sarstedt.com info@sarstedt.com

Sample collection systems, centrifuge and reagent tubes, PCR consumables, liquid handling, mixers, and laboratory automation systems encompassing

sample loading, decapping, recapping, and sorting.

Savyon Diagnostics

Israel • Ashdod Tel: (972) 8-8562920 savyondiagnostics.com info@savyondiagnostics. com

Diagnostic kits for the detection of infectious diseases and genetic screening.

Sciex

USA • Framingham, MA Tel: (1) 877-740-2129 sciex.com sciexnow@sciex.com

Mass spectrometry solutions in the areas of biomarker discovery and omics research, biologics, capillary electrophoresis, genetic analysis, and clinical diagnostics, among others.

Sclavo Diagnostics

International

Italy • Siena

Tel: 39 0577 39 041 sclavodiagnostics.com sclavoexport@sclavo.it

Product line includes laboratory kits for classical serology and bacteriology identification, analytical systems and reagents for clinical chemistry, specific plasma and urinary proteins, and a coagulations division offering a wide range of reagents, controls and calibrators.

SD Biosensor

Korea • Suwon Tel: (82) 31-300-0400 sdbiosensor.com sales@sdbiosensor.com

In vitro diagnostic systems used in POC, hospitals, and central labs. Products include HbA1c analyzers, cholesterol analyzers, and blood glucose monitoring systems, as well as rapid tests for infectious diseases.

Sebia

France • Lisses Tel: (33) 1-6989-8080 sebia.com

Clinical protein electrophoresis equipment and reagents for in-vitro diagnostic testing, intended for diagnosis and mon-

itoring of diseases and conditions such as multiple myeloma, diabetes, as well as hemoglobinopathy and rare pathologies.

Seegene

Korea • Seoul Tel: (82) 2-2240-4000 www.seegene.com info@seegene.com

Multiplex molecular technologies and multiplex clinical molecular diagnostics for infectious diseases.

Sekisui Diagnostics

USA • Burlington, MA Tel: (1) 781-652-7800 sekisuidiagnostics.com questions@sekisui-dx.com

Clinical chemistry and coagulation systems, as well as reagents, infectious disease rapid tests, LINE immunoassays, ELISA kits, enzymes, and specialty bio-chemicals.

Sentinel Diagnostics

Italy • Milan Tel: (39) 02-36217-1

sentineldiagnostics.com sentinel@sentinel.it

In-vitro diagnostic medical devices for routine analysis and specific clinical needs in the areas of clinical chemistry, immunochemistry, coagulation, molecular biology, and colorectal cancer screening.

Sero AS Norway • Oslo Tel (47) 66-858900 sero.no sales@sero.no

SERO is a trusted Norwegian biotech company delivering world-class quality control materials since 1963. The Seronorm® range includes consolidated controls for immunoassay, hormones, fertility, tumor, cardiac and acute markers.

Serosep

Ireland • Limerick Tel: (353) 61-358-190 serosep.com info@serosep.com

Range of laboratory products in the areas of clinical mi-

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LabMedica 400

crobiology, histopathology, molecular diagnostics, immunology, hematology, and environmental analysis.

SFRI

France • Saint Jean d’Illac

Tel: (33) 0-5-56-68-80-50

sfri.fr

contact@sfri.com

In vitro diagnostic instruments and reagents, specializing in human biological analysis and concentrating on routine clinical testing in the hematology, biochemistry, and immunology sectors.

Shenzhen New Industries

Biomedical Engineering (SNIBE)

China • Shenzhen

Tel: (86) 755-26501514 snibe.com

sales@snibe.com

Clinical laboratory instruments and in vitro diagnostic reagents, offering a range of fully automated, integrated CLIA analyzers and matching reagent kits covering more than 100 parameters as well as a full portfolio of immunology, biochemistry and electrolyte products

SEE AD ON PAGE 3 s

Siemens Healthineers

Germany • Erlangen

Tel: (49) 69-6682-6602

siemens-healthineers.com

Broad spectrum of immunoassay, chemistry, hematology, molecular, urinalysis, and blood gas testing systems, along with automation, informatics, and services that can serve the needs of labs of any size today and tomorrow.

Silgan Unicep

USA • Spokane, WA Tel: (1) 208-265-3361

silganunicep.com

A liquid contract manufacturer specializing in the mold and fill of unit-dose solutions. Offers expertise in the mixing, filling, and packaging of liquid components for near-patient tests covering a range of disease states.

Singuway Biotech

China • Shenzhen Tel: (86) 0755-23704711 singuway.com

sales@singuway.com

Molecular diagnostic systems, focusing on isothermal amplification and PCR. Produces a new nucleotide isothermal amplification analyzer capable for testing for virus, infectious disease, microorganism, tumor DNA, antibiotic-resistance DNA, and food safety.

Sinnowa

China • Nanjing Tel: (86) 025-8412-7188 sinnowa.com info@sinnowa.com

Products include automatic

biochemistry analyzer, platelet function analyzer, coagulometer, electrolyte analyzer, hematology analyzer and reagents

Sinocare

China • Changsha Tel: 86-731-8993-5770 sinocareintl.com

intl_mkt@sinocare.com

Specializes in rapid testing products that include a range of blood glucose monitors, HbA1C analyzers, and other solutions focused on diabetes care and management.

SLR Research

USA • Carlsbad, CA Tel: (1) 760-930-9496 SLRresearch.com admin@SLRresearch.com

Broad range of essential biological-based, bulk human disease-state and normal sera, specialty/esoteric antibodies, controls/calibrators and the IRB Clinical Specimen Repository.

Socorex

Switzerland • Lausanne Tel: (41) 21-651-6000 socorex.com socorex@socorex.com

Precision dosing instruments for liquid handling including manual and electronic micropipettes, repeater pipettes, dispensers, pipette controllers, automatic and reusable syringes, pipette tips, and accessories.

SP Bel-Art

USA • Wayne, NJ Tel: (1) 973-694-0500 belart.com salesdept@belart.com

Offers over 3,500 items from safety wash bottles to fume hoods, distributed under well known brand names such as Scienceware, Sterileware, Magic Touch, Spinbar, Secador and H-B Instrument.

Spectrum Diagnostics

Egypt • Cairo Tel: (20) 2-4489-2248 spectrum-diagnostics.com info@spectrum-diagnostics. com

High quality in vitro diagnostic reagents in the areas of clinical chemistry, immunoturbidimetry, hematology, infectious diseases, culture mediums, rapid tests, controls, and more.

Spinreact

Spain • St. Esteve d’en Bas (Girona) Tel: (34) 972-690-800 spinreact.com spinreact@spinreact.com

In vitro diagnostic reagents. Product applications include serology, clinical biochemistry, immunochemistry, rapid tests, blood grouping, coagulation, electrophoresis, and diagnostic instruments.

SSI Diagnostica

Denmark • Hilleroed Tel: (45) 48-29-91-00 ssidiagnostica.com info@ssidiagnostica.com In vitro diagnostic products

for microbiological laboratories, offering rapid diagnostic tests, sampling materials, QC testing for vaccine products, antisera, and several other IVD products.

Stago

France • Asnières sur Seine

Tel: (33) 1-4688-2020 stago.com webmaster@stago.com

Offers a complete system of hemostasis instrumentation and optimized reagent kits for research, as well as for routine analysis.

StatLab

USA • McKinney, TX Tel: (1) 972-436-1010 statlab.com info@statlab.com

Histology, cytology and other consumable supplies to more than 3,000 anatomic pathology laboratories throughout the United States.

STRATEC

Germany • Birkenfeld Tel: (49) 7082-7916-0 stratec.com info@stratec.com

Technological and scientific solutions for the diagnostic and life science industry as an OEM partner for fully automated analyzer systems, smart polymer-based consumables, and modules for IVD companies.

Streck

USA • Omaha, NE

Tel: (1) 402-333-1982 streck.com international@streck.com

Quality controls and calibrators for hematology, body fluids, flow cytometry, ESR, in addition to stabilization solutions, molecular controls and antibiotic resistance kits, and more.

Sugentech

Korea • Deajeon

Tel: (82) 42-364-5000 sugentech.com sales@sugentech.com

Next-generation products for IVD applications including personal POCT products, mobile healthcare products, and personalized diagnosis/treatment solutions based on biotechnology, information technology, and nanotechnology.

Sunostik Medical

Technology

China • Changchun

Tel: (86) 431-8465-0333 sunostik.com sales@sunostik.com

Biochemical analyzers, coagulators, diagnostic reagents, and microwave therapeutic machines.

Super Brush

USA • Springfield, MA

Tel: (1) 413-543-1442 superbrush.com sales@superbrush.com

Leader in the design and manufacturing of foam swabs and applicators providing industries with technically advanced tools for precision

cleaning of laboratory equipment and delicate surfaces, collecting samples, removing excess materials, applying lubricants, solvents, adhesives, topical antiseptics and other solutions.

Surmodics

USA • Eden Prairie, MN Tel: (1) 952-500-7000 surmodics.com orders@surmodics.com

Provides gold standard protein stabilizers, blockers and diluents, colorimetric & chemiluminescent substrates, autoimmune antigens and antibodies and activated slides for microarrays.

Svar Life Science

Sweden • Malmo Tel: (46) 40-53-76-00 svarlifescience.com info@svarlifescience.com

Diagnostic kits and reagents for use in medical assessments. Product applications include clinical autoimmunology, microbiology, histology/cytology, and immunochemistry.

Sysmex Europe

Germany • Norderstedt Tel: (49) 40-527-260 sysmex-europe.com info@sysmex-europe.com

Automated in vitro diagnostic hematology, coagulation and urinalysis analyzers, reagents, and information systems for laboratories and healthcare facilities.

Tecan

Switzerland • Männedorf Tel: (41) 44-922-81-11 tecan.com info@tecan.com

Develops measurement, analysis, and laboratory automation instruments.

Teco Diagnostics

USA • Anaheim, CA Tel: (1) 714-463-1111 tecodiagnostics.com hello@tecodiagnostics.com Instruments and reagents for clinical chemistry, urinalysis test strips, and rapid tests in the areas of pregnancy care, biomarkers, drugs of abuse, infectious diseases, and more.

Tecom Science

China • Nanchang Tel: (86) 791-8811-0293 tecom-cn.com sales@tecom-cn.com

Dedicated to the IVD industry, providing high quality products, such as biochemistry analyzers, hematology analyzers and IVD reagents.

Tellgen

China • Shanghai Tel: 81 3-6636-3711 tosohbioscience.com info@tosoh.com tellgencorp.com sales@tellgen.com

Produces advanced diagnostic products for cancer, autoimmune, cardiovascular, pathogen infections, and reproductive health with immunoassay, molecular, biochemistry, and LC-MS/MS.

Thermo Fisher Scientific

USA • Waltham, MA

Tel: (1) 781-622-1000 thermofisher.com

Analytical instrumentation, lab equipment, automation technologies, reagents and consumables, and LIMS solutions to determine disease markers or analytes of diagnostics interest.

Tianlong Science & Technology

China • Xi’an

Tel: (86) 29-82682132 medtl.net inquiry@medtl.com

Professional PCR detection devices, reagent kits and services for the molecular diagnostics market. Products include nucleic acid extractors, real time PCR systems and detection kits, PCR thermal cycler, and lab automation systems.

Tokra Medikal

Turkey • Ankara

Tel: (90) 312 397 0173 tokra.com.tr tokra@tokra.com.tr

In vitro diagnostic Instrumentation, reagents, and consumables for clinical and research laboratories in the field of haemostasis.

Tokyo Boeki Medisys

Japan • Tokyo Tel: (81) 42-587-7777 tb-medisys.co.jp

Multifunction, small-sized automatic biochemical analyzer that is capable of processing 270 tests an hour.

TopAir Systems

USA • Needham, MA

Tel: (1) 857-340-1201

topairsystems.com sales@topairsystems.com

Delivers advanced, energy-efficient laboratory safety solutions with a focus on customizability. Combining proprietary technologies, global compliance, and industry expertise, TopAir Systems ensures tailored safety, reliability, and sustainability for labs worldwide. Products include fume cupboards, Ductless fume hoods, biosafety cabinets, laminar clean benches and forensic products.

Tosoh Bioscience

Japan • Tokyo Tel: 81 3-6636-3711 tosohbioscience.com info@tosoh.com

In vitro diagnostic analyzers, products and services for Immunoassay and HPLC applications.

Toyobo

Japan • Osaka Tel: (81) 6-6348-3888 www.toyobo-global.com

Automated urine cell analyzers and related consumables, in addition to reagents for molecular diagnostics.

Trinity Biotech

Ireland • Bray Tel: (353) 1-276-9800

trinitybiotech.com

info@trinitybiotech.com

Diagnostic test kits for the clinical laboratory and point-of-care. The company’s products are used to detect infectious diseases, autoimmune disorders, hemoglobin disorders, as well as for the detection, monitoring and control of diabetes.

Turklab

Turkey • Izmir (90) 232-376-80-81 turklab.com.tr

info@turklab.com.tr

Diagnostic test kits for infectious diseases, tropical diseases, tumor markers, cardiac markers, blood grouping tests, and others.

Tyson Bioresearch

Taiwan • Zhunan Township Tel: (886) 37-585988 tysonbio.com sales_int@tysonbio.com

In advanced rapid in vitro immunodiagnostic test systems, including blood glucose monitoring systems for everyday use, and electrical biosensing systems.

Unitma

Korea • Seongnam Tel: (82) 31-721-8003 unitma.com unitma@unitma.com

Manual and fully automated tissue microarrayers, as well as paraffin block trimmers, for various lab applications.

URIT Medical

China • Guilin Tel: (86) 773-2288586 urit.com export@uritest.com

Diagnostic products covering urinalysis, hemanalysis, chemistry analysis, POCT, immunoassay, molecular biology, LIS software and medical electronic products.

Vazyme

China • Nanjing Tel: (86) 400-168-5000 vazymeglobal.com info.biotech@vazyme.com

Dedicated to the design, manufacture, and application of bioactive proteins, continuously expanding the application fields of its core technologies in life sciences, in-vitro diagnostics, biomedicine and other.

Vector-Best

Russia • Novosibirsk Tel: (7) 383-3326-749 vector-best.ru vbmarket@vector-best.ru ELISA kits and clinical chemistry reagents for public health.

Veda.Lab

France • Alençon Tel: (33) 2-33-27-56-25 vedalab.com

In vitro immunodiagnostic reagents and instruments. The

company’s product range includes quantitative and qualitative rapid tests and reader for the quantitative interpretation of immunochromatographic qualitative rapid test cards.

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Verichem Laboratories

USA • Providence, RI

Tel: (1) 401-461-0180 verichemlabs.com customerservice@ verichemlabs.com

Provides a comprehensive line of CLIA-compliant clinical reference materials, calibration verifiers, chemistry standards, linearity confirmation materials, and support services.

VICOTEX

Vicotex

Switzerland • Pully Tel: (41) 21-728-4286 vicotex.com contact@vicotex.com

Products for central sterilization.

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Vircell

Spain • Granada Tel: (34) 958-44-12-64 vircell.com info@vircell.com

Development and production of ready-to-use reagents for the diagnosis of infectious diseases by techniques ranging from the traditional cell culture to the most innovating developments in the field of molecular biology.

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Visby Medical USA • San Jose, CA (1) 833-468-4729 visbymedical.com support@visby.com

The company’s proprietary technology platform is an instrument-free single-use PCR platform that offers tests for serious respiratory and sexually transmitted infections.

Vitro

Spain • Madrid

Tel: (34) 91-382-16-20 vitro.bio

vitro@vitro.bio

In vitro diagnostic reagents, platforms, and related services in the fields of pathology, molecular biology, cytometry, clinical chemistry, healthcare software and instruments for clinical laboratories.

Vitrosens

Turkey • Istanbul (90) 216-784-41-01

vitrosens.com info@vitrosens.com

Rapid diagnostic test kits for infectious diseases, cardiovascular diseases, inflammation, tumors, drugs of abuse, pregnancy, POCT, and animal diseases. Molecular diag-

nostic products for respiratory infectious diseases, gastrointestinal pathogens, and sexually transmitted diseases.

VivaProducts

USA • Littleton, MA 1-978-952-6143 info@vivaproducts.com

The company has supplied protein concentration products to clinical labs for years. Its BJP devices concentrate urine and CSF proteins prior to electrophoresis for diagnosis of multiple myeloma and other diseases. They are US FDA registered medical devices used around the world.

Wama Diagnostica

Brazil • São Carlos Tel: (55) 16-3377-9977 wamadiagnostica.com.br info@wamadiagnostica.com

Kits and reagents for laboratory diagnostic, especially immunodiagnostics. Its product portfolio includes immuno-chromatographic tests (lateral flow), urine strips, reagents, urine analyzers, coagulation analyzers and microplate readers

Waters

USA • Milford, MA Tel: (1) 508-478-2000 waters.com customerservice@waters. com

Ultra performance liquid chromatography (UPLC), high performance liquid chromatography (HPLC), chromatography columns and chemistry products, mass spectrometry (MS) systems, thermal analysis and rheometry instruments.

WESAIL Biotech

China • Dongguan Tel: (86) 769-22899366 en.wesailbio.com customer@wesailbio.com

Reagents and analyzers, including colloid gold and immunofluorescence platforms, meeting diagnostic needs in various disease areas.

Werfen

Spain • Barcelona Tel: (34) 934-010-101 werfen.com

Diagnostic instruments in the areas of hemostasis, autoimmunity, and acute care diagnostics. The company develops and manufactures customized assays and biomaterials through its OEM business line.

SEE AD ON PAGE 36 s

West Medica

Austria • Wiener Neudorf Tel: 43 (0) 2236 892465 westmedica.com vienna@westmedica.com

Designs equipment for laboratory research and microscopy. Provides an innovative automated microscopy range for hematology labs.

Wiener

Laboratorios

Argentina • Rosario Tel: (54) 341-432-9191 wiener-lab.com.ar marketing@wiener-lab.com

Diagnostics systems, including reagents, analyzers and software for use in clinical and specialized laboratories as well as blood banks. Its varied range of products comprises analyzers and kits for clinical chemistry, hematology, hemostasis, ESR, immunology and urinalysis.

WizBioSolutions

Korea • Seongnam (82) 70-7605-5066 wizbiosolution.com sales@wizbiosolution.com

Provides total solutions in point-of-care molecular diagnostics from research reagents to molecular diagnostic kits.

Wondfo Biotech

China • Guangzhou

Tel: (86) 400-830-8768 en.wondfo.com.cn sales@wondfo.com.cn

Products and services for rapid diagnosis and chronic disease management. The company’s product

range includes rapid diagnostic test kits for infectious diseases, including COVID-19, hepatitis, adenovirus, rotavirus, pneumonia, dengue, and malaria, among others.

Xunda

China • Shanghai

Tel: (86) 21-57687666 xunda-med.com xunda@xunda-med.com

Cinical testing equipment including a range of electrolyte analyzer series, western blot system series and erythrocyte sedimentation rate analyzer series.

Yashraj Biotechnology

India • Navi Mumbai Tel: (91) 22-6812-5300 yashraj.com marketing@yashrajbio.com

The company supplies high-quality antigens and antibodies to the diagnostics industry, manufactures assays and controls and offers OEM services.

YD Diagnostics

Korea • Yongin Tel: (82) 31-329-2000

yd-diagnostics.com admin@yd-diagnostics.com

Diagnostic products for liquid-based cytology, MDx, and urinalysis. Products available include processors, fully automated systems, rapid tests, strips, and chemistry reagents.

YHLO Biotech

China • Shenzhen Tel: (86) 755-26601910 www.szyhlo.com marketing@szyhlo.com

In vitro diagnostic instruments and reagents, based on CLIA, ELISA, LIA and immunofluorescence platforms. Specialized in diagnosis of autoimmunity, reproductive health, diabetes, and infectious diseases.

ZEISS

Microscopy

Germany • Oberkochen Tel: (49) 7364-20-3800 www.zeiss.com/microscopy microscopy@zeiss.com

Optical and optoelectronic industries, including products for semiconductor and optoelectronic technology, life sciences, healthcare, and eye care.

ZeptoMetrix

an antylia scientific company USA • Buffalo, NY Tel: (1) 716-882-0920

Provides high-quality controls for molecular diagnostics. The company’s products support accurate testing and research, ensuring reliable results for clinical, laboratory, and life science applications worldwide.

SEE AD ON PAGE 11 s

Zytomed Systems

Germany • Berlin Tel: (49) 30-804-984-990 zytomed-systems.com international@ zytomed-systems.de Antibodies and reagents with an emphasis on immunohistochemistry, as well as reagents for in situ hybridization

Zybio China • Chongqing Tel (86) 23-6869-0698 zybio.com info@zybio.com

In vitro diagnostic equipment for clinical chemistry, immunoassay, molecular diagnosis, POCT, hematology, microbiology, pathological, and more.

Companies by Country

ARGENTINA

AADEE

Diestro

Wiener Laboratorios

AUSTRALIA

Atomo Diagnostics

Invetech

Genetic Signatures

AUSTRIA

AMEDA Labordiagnostik

Dialab

Greiner Bio-One

International West Medica

BELGIUM

Biocartis

Coris BioConcept

D-tek

DIAsource

ImmunoAssays

Biodin

BRAZIL

Biotécnica

Labtest

Wama Diagnostica

CANADA

MedMira Laboratories

Precision Biologic

Pro-Lab Diagnostics

Response Biomedical

CHINA

AccuBio Tech

Allsheng Instruments

Assure Tech

Autobio Diagnostics

AVE Science & Technology

B&E Bio-technology

BIOBASE

Bioer Technology

BioPerfectus

Biotech Company

Nanchang

Biotime Biotechnology

Blue Cross Bio-Medical

Caretium Medical

Instruments

Chemclin Biotech

Chemtron Biotech

Cornley High-Tech

Daan Gene

DiagCor Life Science

Dirui Industrial

Dymind Biotech

Edan Instruments

Emperor Electronic

Technology

ERA Biology

Fapon Biotech

Fosun Diagnostics

Genrui Biotech

Getein Biotech

Goldsite Diagnostics

Gongdong Medical

Technology

Heales

Haier Medical and Laboratory Products

Hipro Biotechnology

Horron XLH Medical

IncreCare

InTec Products

Kangrun Biotech

Kehua Bioengineering

Labnovation

Technologies

Landwind Medical

LifeReal Biotechnology

Lifotronic Technology

Lituo Biotechnolgy

Lumigenix

Maccura Biotechnology

Macro & Micro Test

Medcaptain Medical

Technology

MedicalSystem

Biotechnology

Mindray

Perlong Medical Equipment

Prokan Electronics

Rayto Life and Analytical Sciences

RealMind Biotech

Sansure Biotech

Singuway Biotech

Sinnowa

Sinocare

Shenzhen New Industries

Biomedical Engineering

(SNIBE)

Sunostik Medical

Tecom Science

Tellgen

Tianlong Science & Technology

Urit Medical

Vazyme

WESAIL Biotech

Wondfo Biotech

Xunda

YHLO Biotech

Zybio

CZECH REPUBLIC

BioVendor Group

COLOMBIA

Carperlabs

DENMARK

BioPorto Diagnostics

Kementec

Radiometer Medical

SSI Diagnostica

EGYPT

Spectrum Diagnostics

Euroimmun

Gold Standard Diagnostics

Hecht - Assistent

Hettich

Human Diagnostics

Immundiagnostik

Kabe Labortechnik

LDN Labor

Diagnostika Nord

Leica Microsystems

Macherey-Nagel

Merck KGaA

Paul Marienfeld

Preventis

Qiagen

R-Biopharm

Ratiolab

Sarstedt

Siemens Healthineers

STRATEC

Sysmex Europe

ZEISS Microscopy

Zytomed Systems

GREECE

Medicon

HUNGARY

77 Elektronika

Diagon

Diatron

INDIA

Accumax Lab Devices

AGD Biochemicals

Carewell Biotech

Everlife CPC Diagnostics

Genes2Me

HiMedia Laboratories

Labline Equipments

Magnus Opto Systems

Medsource Ozone

FINLAND

Biohit HealthCare

HyTest

Medix Biochemica

Reagena

FRANCE

Aidian

Biolabo

BioMerieux

Biosynex

Chromagar

Diagast

ELITech Group

Eurobio Scientific

Horiba Medical

Melet Schloesing

Laboratories

NG Biotech

Sebia

SFRI

Stago

Veda.Lab

GERMANY

AESKU Diagnostics

AHN Biotechnologie

Analyticon

Biotechnologies

Anbio Biotechnology

Astra Biotech

Axiom Diagnostics

Berthold Technologies

BIORON Diagnostics

Brand

CANDOR Bioscience

Chromsystems

DiaSys Diagnostic

Systems

DWK Life Sciences

Eppendorf

Biomedicals

Micro Lab Instruments

Microlit

Q-Line Biotech

Yashraj Biotechnology

IRELAND

Serosep

Trinity Biotech

LGC Clinical Diagnostics

ISRAEL

Savyon Diagnostics

ITALY

AB Analitica

Adaltis

Alifax

Biomat

Biosigma

Callegari

Chema Diagnostica

CLONIT

Das

DIA.PRO Diagnostic Bioprobes

DiaSorin

Diesse Diagnostica

Eurospital FL Medical

Kartell Labware

Liofilchem LP Italiana

Menarini, A., Diagnostics Sentinel

JAPAN

Apel Denka

Iwaki

Nihon

Tokyo

Tosoh

Absology

Asan

Boditech

DxGen

GMMC

GenBody

GC Medical

Humasis

i-Sens

KH Medical

NanoEntek

NanoHelix

Noul

Protia

SD Biosensor

Sugentech

Seegene

Unitma

WizBioSolutions

YD Diagnostics

NETHERLANDS

Eurotrol

PHC Europe

Sakura Finetek Europe

Sero AS

POLAND

Cormay Diagnostics

Hepy HTL

MPW Med. Instruments

PORTUGAL

Esteriplas

RUSSIA

Vector-Best

SINGAPORE

Esco Lifesciences

SPAIN

BioSystems

Certest Biotec

Cytognos

Deltalab

Grifols International

JP Selecta

Linear Chemicals

Monlab

Operon

Quimica Clinica Aplicada

RAL Tecnica

Spinreact

Vircell

Vitro

SWEDEN

Boule Medical CellaVision

HemoCue

LABEX Reagens

Nordic Biomarker

Svar Life Science

SWITZERLAND

Agappe Diagnostics

Bühlmann Laboratories

Roche Diagnostics

Socorex

Tecan

Vicotex

TAIWAN

Apex Biotechnology

General Biologicals

GeneReach

Biotechnology

LabTurbo Biotech

RBC Bioscience

Tyson Bioresearch

TURKEY

Nüve

Turklab

Tokra Medikal

Vitrosens

UK

Alpha Laboratories

Apacor

Astell Scientific

BBI Solutions

EKF Diagnostics

ELGA Labwater

Fortress Diagnostics

Immunodiagnostic

Systems

Logical Biological

Mast Group

Medical Wire & Equipment

Novacyt

Owen Mumford

Oxford Nanopore

Randox Laboratories

USA

Abbott Diagnostics

Access Bio, Inc.

Acon Laboratories

Agena Biosciences

Agilent

AirClean Systems

ALCOR Scientific

ALPCO

Alfa Scientific Designs

Ansh Labs

Atlas Link

AUDIT MicroControls

Awareness Technology, Inc.

Baebies

BD Diagnostics

Beckman Coulter

Benchmark Scientific

Biocare Medical

BioCheck

Biomerica

Bio-Rad Laboratories

Bio-Techne

Biotron Diagnostics

Brooks Automation

Bruker

Calbiotech

CareHealth America

Carolina Liquid Chemistries

CDG Biotech Corp.

Cepheid

Chembio Diagnostic Systems

Clinisys

Copan Diagnostics

Co-Diagnostics, Inc.

(Co-Dx)

CTK Biotech

Diagnostic Automation

Diamond Diagnostics

Diazyme Laboratories

Drucker Diagnostics

Dynex Technologies

Fluid Metering

Fortis Life Science

Fujirebio Diagnostics

Globe Scientific

Hamilton Company

Hardy Diagnostics

Healgen Scientific

Helena Laboratories

Helmer

HEMCO

Hologic

Hycor Biomedical

IBL-America

Illumina

Immuno Concepts

InBios International

Integra Biosciences

Kamiya Biomedical

Labcon

Lampire Biological

Laboratories

Lee Company, The LifeRiver Biotech

LifeSign

Lumiquick Diagnostics, Inc.

LW Scientific

Mawi DNA Technologies

Mayo Medical Laboratories

Medica Corporation

Meridian Biosciences

MicroBioLogics

Monobind

Monocent Moss

MP Biomedicals

New England Biolabs

Nikon Instruments

Nittobo America

Neogen

Nova Biomedical

NuAire

Oasis Diagnostics

Omega Bio-Tek

OraSure Technologies

Polymedco

Porex

Puritan Medical Products

Quanterix

Quantimetrix

QuidelOrtho

Revvity

RNA Medical

SA Scientific

Saladax Biochemical

Salimetrics

Sciex

Sekisui Diagnostics

Silgan Unicep

SLR Research

SP Bel-Art

StatLab

Streck

Super Brush

Surmodics

Teco Diagnostics

Thermo Fisher

Scientific

TopAir Systems

Verichem Laboratories

Visby Medical

VivaProducts

Waters

ZeptoMetrix

The Intelligent Analyzer

GEM Premier 5000 blood gas testing system provides automated quality assurance with every whole-blood* sample. Now with next-generation Intelligent Quality Management (iQM2), featuring IntraSpect™ technology, potential errors are detected not only before and after, but also during sample analysis, along with real-time correction and documentation. Plus, it’s simple—just change the all-in-one GEM PAK once a month. So regardless of testing location or point-of-care operator, quality results and compliance are assured with every sample. Real-time assurance and advanced simplicity. Now that’s intelligent.

For more information, contact your local Werfen representative. werfen.com *Heparinized.