HOK
Biomedical + Translational Health Facilities
“ We interviewed many experienced firms for the IRC (now WIMR) project. In the end, we selected HOK because we were not only impressed with the firm’s breadth of experience, but also with the team’s personal approach to project delivery. We have not been disappointed.” - Mr. Mark Wells Assistant Dean of Facilities University of Wisconsin - Madison
B I O M E D I C A L + T R A N S L AT I O N A L H E A LT H FA C I L I T I E S A S A M P L E O F O U R P R O J EC T S F O C U S E D O N T R A N S L AT I O N A L A N D BIOMEDICAL RESEARCH
W IM R
CEDA RS
CRICK
TCMC
OS U
University of Wisconsin, Wisconsin Institutes for Medical Research
Cedars-Sinai Medical Center, Advanced Health Sciences Pavilion
The Francis Crick Institute
The Commonwealth Medical College
The Ohio State University Wexner Med. Ctr. Cancer Hospital and Critical Care Tower
UMB
EM O RY
U. F LO RIDA
U. B U F FA LO
RIM ED
University of Maryland, Baltimore Health Sciences Facility III
Emory Univ. Whitehead Biomedical Research Building
University of Florida, Lake Nona Academic and Research Center
University at Buffalo School of Medicine and Biomedical Sciences
Fondazione RiMED Biomedical Research & Biotechnology Center
HOK
HOK is a global provider of planning, design and delivery solutions for the built environment.
Since the firm’s founding in 1955, HOK has developed into one of the world’s largest, most diverse and respected design practices. The firm employs more than 1,600 professionals linked across a global network of 23 offices on three continents.
HOK SCIENCE + TECHNOLOGY
In response to the growing need to fully service the unique organizational and scientific challenges facing our clients in science and technology organizations, the HOK Science + Technology group was born.
This group of expert professionals brings innovative facility design to our most complex projects around the world.
KING ABDULL AH UNIVERSIT Y OF SCIENCE A ND TECHNOLOGY
LEED PLATINUM Certification
S U S TA I N A B L E D E S I G N
HOK has become one of the world’s preeminent sustainable design experts and many of our projects have received LEED Certification.
We have made the commitment to design facilities from the whole building perspective.
The new model of health sciences is changing from a focus on treatment of
models to fruition for academic
disease to a focus on health.
medical centers.
The increasing convergence
Present day function and future
of knowledge and capability at
flexibility that allow for growth and
the most fundamental level of
renewal are the tip of the iceberg.
biological sciences and systems
Evolving trends in medicine and
requires moving away from
treatment, including translational
reparative medicine and nursing
medicine, genomic medicine and
to a new model of predictive and
research, proteomics, and evolving
proactive public health.
patient-centered care models are shaping today’s academic medical
An interdisciplinary model for
centers.
education, research, and the practice of medicine is at the
Environments for academic
forefront of design for health
medical research and education
sciences.
must be ready to accommodate tomorrow’s innovation. HOK
HOK develops innovative design
designs buildings that maximize
solutions which create aligned
opportunities for researchers and
vision and bring translational
physicians to share knowledge.
T R A N S L AT I O N A L R E S E A R C H FAC I L I T I E S
T R A N S L AT I O N A L R E S E A R C H FAC I L I T I E S
If the goal of academic medical centers engaged in translational research is
application of new technologies
creating novel, basic scientific
for the patient-driven environment,
discoveries that translate
including early patient testing and
into clinical applications, then
evaluation using traditional and
collaboration, technology and its
genomic techniques.
critical infrastructure are what enables development of bench-to-
By building partnerships
bedside therapies.
that facilitate the interaction between basic research and
The design of these facilities
both clinical medicine and clinical
must enhance the communication
trials, innovation can flourish
link between research scientists
because information can flow
and physicians vital to cutting-
freely between researchers and
edge research that connects
clinicians. Many major medical
basic research to patient care.
centers are looking to of predictive
Translational techniques are
medicine to identify biological
a core competency central to
markers to identify individuals
comprehensive cancer care,
at high risk for developing
emphasizing the bench-to- bedside
diseases using techniques such
potential. Facility design must
as genomics, proteomics, and
enable the development and
cytomics.
S IZ E 469,000 sq. ft. COMPLETION 2008
UNIVERSIT Y OF WISCONSIN, WISCONSIN INSTITUTES FOR MEDICAL RESE ARCH ( WIMR ) Madison, Wisconsin
The new Wisconsin Institutes for Medical Research (WIMR) is the centerpiece of the Medical School’s efforts at creating the world’s preeminent cancer research institute. The seven-story East Tower is the first of WIMR’s three planned interdisciplinary research towers to house researchers in highly interactive spaces designed to cultivate collaboration.
UW researchers from a wide range of backgrounds occupy the WIMR, working together to study the underlying mechanisms of cancer, identifying potential treatments and cures then rapidly translating their discoveries into promising new therapies for patients at the adjacent clinic/hospital. Adjacent to UW Hospitals and Clinics, WIMR scientists can easily interact with clinicians and are within sight of the patients whose lives they hope to improve. The East Tower, eliminates laboratory walls, places office areas close to labs, allows rapid sharing of complex equipment and facilities and includes interaction space on every floor. Alternate floors are also joined by twostory atriums to further enhance communication and collaboration. The Advanced Imaging and Radiation center, with walls and
UNIVERSIT Y OF WISCONSIN
ceilings more than eight feet thick, is designed to be vibrationfree. Equipment includes every imaging modality for human and animal research at the molecular level as well as a 30-ton cyclotron for production of short-lived imaging agents and computerized chemical synthesis. Complete facilities are provided for the development of state-of-theart, three-dimensional radiation oncology application development. The first floor and basement also house one of the nation’s largest rodent and primate vivaria. Lab floors are organized to support the multi-disciplinary approach to research, so that all parties involved in a specific research area are located on the same floor. Teams that require additional space can overflow onto another floor via the twostory atria without losing the ability to interact.
S IZ E 820,000 sq. ft. COMPLETION 2013 4 LEED GOLD
CEDA RS-SIN A I M EDICA L CEN T ER A D VA N C E D H E A LT H S C I E N C E S P AV I L I O N Los Angeles, California
Cedars-Sinai is dedicated to providing the best possible care for its patients.
HOK guided project planners at Cedars to realize the path to profound change in their organization would come through a translational facility that would combine patient care, clinical offices, research, physician education and training.
Utilizing an incredibly flexible model, the facility was planned and designed to provide outpatient procedure services in Cardiac Care and Neuroscience. Attracting and retaining the “triple-threat� physicians (educator/researcher/physician) is a primary mission of Cedars-Sinai. The facility provides for procedure suites, clinic/office space, and research facilities, as well as a training center with a simulation center and debrief rooms. Every doctor who is assigned to this facility will be an active researcher and practicing physician, and
CEDA RS-SIN A I M EDICA LCEN T ER
will be able to directly apply their research into highly personalized patient care. A connected link to the main hospital facility will allow for inpatients to benefit from procedures in the state-of-theart procedure suites, and be transferred back to their rooms in the hospital. The building will also house a fully functioning pharmacy, Imaging center (including MRI and CT), and a centralized conferencing facility to allow for maximum interaction of physicians.
S IZ E 635,000 sq. ft. COMPLETION 2014
THE FR ANCIS CRICK INSTITUTE London, United Kingdom
HOK designed what will become one of the world’s major research centers, covering research in a broad range of biomedical sciences including translational research.
Six leading UK research organizations have come together to build this hub for research into the development, prevention and treatment of significant diseases.
HOK designed what will become one of the world’s major research centers, covering research in a broad range of biomedical sciences including translational research. Six leading research organizations - The Medical Research Council, Cancer Research UK, The Wellcome Trust, UCL (University College London), Imperial College London and King’s College London - have come together to build the Francis Crick Institute: the hub for research into the development, prevention and treatment of diseases such as cancer, heart disease/stroke, infections, and neurodegenerative diseases. The laboratories are arranged over four floors, with each floor consisting of four interconnected blocks which will bring together staff working in different fields.
THE FR ANCIS CRICK INSTITUTE
The laboratories are designed to be adaptable to change as new scientific opportunities emerge in the future. This facility will support highly translational research as it is equipped with high-performance IT infrastructure for virtual collaboration, integrated analysis and bedside decision support as well as a state-of-the-art imaging center to further promote human subject translational research. More than 7,500 sq. ft. of biocontainment space (at BSL-3 or higher) will allow for world-leading research into diseases such as influenza, malaria, tuberculosis and HIV. A state-of-the-art, 85,000 sq. ft. barrier research facility includes: SPF (Specific Pathogen Free), EXP (Experimental Barrier), BSL3, UHS (Unknown Health Status), Aquatics and Imaging.
S IZ E 194,263 sq. ft. COMPLETION 2011
T H E C O M M O N W E A LT H M E D I C A L C O L L E G E Scranton, Pennsylvania
HOK worked with The Commonwealth Medical College to create their vision of a freestanding medical school with no university affiliation. Within this independent structure, TCMC is able to partner with health science programs throughout the region, offering students a variety of educational experiences; preparing them to become community physicians practiced in evidence-based medicine.
The west research wing and east educational wing surrounds a shared courtyard. The linkage between the two buildings acts as the central hub where students can gather and socialize at the grand porch, courtyard and cafĂŠ. To the east, public ground floor spaces include additional student common areas, a bookstore and lobby for the 250 seat auditorium. The Research space is 63,929 square feet and can support 16 Principal Investigators (PIs) for wet research and 4 PIs for bioinformatics. In 35 laboratories, researchers can focus on diseases that are relevant to the area, including issues with aging as well as cancers of the colon, breast and lung. The state of the art flexible labs, stairways and common areas offer ample daylight and promote interaction and collaboration. A 5,000 sq.
T H E C O M M O N W E A LT H M E D I C A L C O L L E G E
ft. vivarium and cagewash, as well as imaging facilities, support biomedical research for students and faculty. The ground floor of the north structure contains a simulation facility with 12 mock exam rooms for standardized patients (actors portraying patients) and several suites for simulated surgical procedures using high-fidelity robotics, as well as breakout rooms and small group work areas. The gross anatomy lab is also included in this area. All simulation spaces offer high definition video for real time viewing by professors or other students, or for later review. The new buildings incorporate principals of sustainable development and should garner the facility LEED Certification.
S IZ E 1,100,000 sq. ft. COMPLETION 2014
T H E O H I O S TAT E U N I V E R S I T Y W E X N E R MEDICAL CENTER, JAMES CANCER H O S P I TA L A N D S O L O V E R E S E A R C H INSTITUTE AND CRITICAL CARE TOWER Columbus, Ohio
As part of the University Medical Center’s South Campus Master Plan Implementation this project includes growth and replacement of the Arthur G. James Cancer Hospital and associated translational research facilities, critical care beds, surgery and imaging to create The Ohio State’s Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
S IZ E 198,000 sq. ft. COMPLETION 2009
UNIVERSIT Y OF CENTR AL FLORIDA SCHOOL OF BIOMEDICAL SCIENCE Orlando, Florida
Providing quality undergraduate and graduate programs in the biomedical sciences to build robust research programs focused on cancer and cardiovascular, neurological, and infectious diseases is the mission of the Burnett School of Biomedical Sciences.
HOK’s design creates the cornerstone facility of the new research quadrant.
As envisioned in HOK’s campus masterplan, this facility is the first of several buildings that will ultimately create a biomedical cluster; providing UCF with key health partnerships to allow for the rapid translation of laboratory findings into new patient cures. The School is committed to its role in developing technology-based industry in Florida.Innovative partnerships formed with the College of Optics and Photonics and the NanoScience Technology Center facilitate interdisciplinary research and education programs in the application of photonics, bioinformatics and nanoscience to biomedical problems. HOK designed this facility to “ (HOK are) the first architects I have worked with that listened to our issues, and responded with contemporary and cost effective solutions.” Robert N. Gennaro, PhD Burnett College of Biomedical Sciences
support the new undergraduate curriculum in biomedical sciences; updated to better prepare students for admission to medical/ health profession schools
UNIVERSIT Y OF CENTR AL FLORIDA
and graduate programs in the biomedical sciences. The research center includes four levels of labs and investigator offices, specialty core support labs, a transgenic animal facility (vivarium), faculty offices and administrative suite. Core lab areas include space for two Electron Microscopes, two Confocal Microscopes and associated image processing; large x-ray crystallography suite; multiple rooms for light and fluorescence microscopy, as well as conventional dark rooms. Containment space is an enhanced BSL-3, with HEPA filtration of all exhaust air, and shower-out ability. HOK worked closely with UCF to include sustainable features such as FSC Certified lab casework and wood materials; as well as energy recovery on general lab exhaust.
S IZ E 325,000 sq. ft. COMPLETION 2001 4 L EED S I LV ER
EMORY UNIVERSIT Y W H I T EH E A D B I O M ED I C A L R ES E A R CH B U IL D IN G Atlanta, Georgia
This eight-story interdisciplinary biomedical research facility for genetics, cell biology, physiology and neuroscience research includes special facilities such as animal housing, tissue culture, and environmental health and safety support facilities. It supports BSL-2 and BSL-3 research activities.
S IZ E 330,000 sq. ft. COMPLETION 2017
U NI V ERSI T Y O F M A RY L A N D, B A LT I M O R E H E A LT H S C I E N C E S FACI L I T Y 3 Baltimore, Maryland
This new facility for the University’s Medicine, Dentistry and Pharmacy Schools is the third phase of the Health Science Facility at UMB, and is expected to help advance UMB’s position as academic research leaders, and to recruit the best faculty, students and staff. The building is sited among the three schools’ existing facilities to maximize interactions and the sharing of resources.
S IZ E 100,000 sq. ft. COMPLETION 2012 4 L E E D P L AT I N U M
UNIVERSIT Y OF FLORIDA ACADEMIC A N D R E S E A R C H C E N T E R AT L A K E NONA Orlando, Florida
This new academic and research facility will complement the Lake Nona “Medical City� institutions. The UF College of Pharmacy, including the newly established pharmacometrics and systems pharmacology initiative in the interdisciplinary Institute of Therapeutic Innovation, will relocate its Orlando campus to this vibrant new building.
Sited on approximately five acres “ All of the HOK team have been extremely responsive to the needs of the faculty and the Lake Nona development. We have been impressed with their BIM capabilities, their team approach with the Construction Manager and the willingness to meet the goals of UF for a minimum Gold LEED building.� Carol J. Walker, Assistant Vice President UF Facilities Planning & Construction
directly adjacent to the Sanford Burnham Institute, the new center takes a dramatic form to represent the innovative, collaborative and life changing activities housed inside. The research areas include two floors of open laboratories consisting of large, ballroom plan island bench areas with mobile sinks and casework, supported by fume hood and BSC alcoves and other support functions at either side, and are located to maximize the views of the wooded preserve to the south. A glass wall along the inboard side of the research laboratories provides a visual connection to the office zone for faculty and graduate students. One floor is devoted specifically to research conducted in enhanced environments.
UNIVERSIT Y OF FLORIDA
The first floor of the building accommodates a state of the art conference center, consisting of a large, media-rich auditorium, break out conference rooms, and a large media-equipped lobby capable of accommodating social, academic and student events. Amenities are centrally located to support and connect the laboratories and offices. The remainder of the first floor is clinical research space operated by the Institute on Aging, an interdisciplinary group involved in the areas of research, education and health care across all UF Colleges and Departments. Passive and active design strategies through the building led the facility to a LEED Platinum Certification.
SIZE
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S IZ E 538,000 sq. ft.
COMPLETION
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COMPLETION 2014
FONDA ZIONE RI.MED BIOMEDICAL RESE ARCH AND BIOT ECHNOLOGY CEN T ER Carini, Sicily
This new Biomedical Research and Biotechnology Center is designed to be a new center for translational research pairing scientific researchers with practicing clinicians on a common campus. The master plan is comprised of a large research complex, a future 300-bed hospital and common shared elements such as an auditorium, employee cafĂŠ, administration complex and gardens.
S IZ E 500,000 sq. ft. (Phase I) COMPLETION 2016
U N I V E R S I T Y AT B U F F A L O , S C H O O L O F MEDICINE AND BIOMEDICAL SCIENCES Buffalo, New York
Located at the center of the region’s emerging bio-sciences corridor, this new medical school development will anchor a mixed-use district on campus and bring 1,200 students, faculty and staff downtown.
The new center will create connections that allow students, faculty, biomedical researchers and clinicians to move easily from classroom to bedside to lab.
HOK