Aging Matters, Issue 2, 2014 by International Antiaging Systems (IAS)

No 2, 2014

The rotational origin of diseases and aging

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Dr Walter Pierpaoli discusses the pineal age-clock

PLUS: Nature’s moisturiser Avoiding a hospital bed Dr Ward Dean answers your questions FREE eBook

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*Restrictions may apply in some countries. All information is educational and does not replace your physician and is subject to IAS terms and conditions which may change without notice. Restrictions may apply in some countries. All information is educational and does not replace your physicians and is subject to IAS terms and conditions which may change without notice.

Welcome

Index

When finding solutions to one’s own health issues, I don’t believe that price is at the top of the list, although naturally, value for money is important. As such, I don’t usually “bang on about price” but since one spurious organization has been trying hard to compare themselves to IAS, please let me point out a few facts.

Welcome -Phil says thanks for finding the time 3 The rotational theory of aging -Dr Pierpaoli’s views on aging 4 Avoiding a hospital bed -By Dr. Richard Lippman 9 Hyaluronic acid, nature’s moisturizer -Good news for joints and skin 14 Dr Ward Dean Q&A -Dr Dean answers your questions 17 Featured products -Best sellers and new items 23 Testimonials & Explanations -Nice people, nice comments 32 Complete product A-Z list and prices -Find everything in-stock here 32 Condition cross-reference list -Find the right product for you 45 Contact details -Get in touch with IAS today 50

If you compare like-with-like, (i.e. brands) and note the numbers of units and the dosage too, you will soon see that IAS is competitive. Plus there is the amazing range of supplements IAS stocks; add in our health professional assistance, (including customer service via phone) and that value for money is greatly expanded. Plus, IAS is busy introducing quality generics at superb prices; for example we currently offer piracetam from 18 cents a tablet (800 mg), there’s GH3 from less than 20 cents a capsule (100 mg) and even natural thyroids from as little as 25 cents a dose! In addition, IAS sponsors the research and the dissemination of the latest information; this means when you buy from IAS you help to further the science. Lastly, how many others offer you a quality magazine like this Aging Matters™ magazine for nothing?

Phil Micans, MS, PharmB Editor, Aging Matters™ Magazine Medical Advisor: Ward Dean, M.D.

Tomorrow’s treatments today ™ IAS is dedicated to helping you access the world’s latest commercially available supplements- to give you and your family real choices in health and wellness. IAS promises you: •

Product quality: We only stock the best quality products. With the right materials and formulation you are more likely to get the results you desire.

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Original brands: We have the original brands - i.e. the same ones used in the clinical trials. These brands are used by top health professionals.

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Choice: The largest range of medicines, hormones and supplements. If you are looking for things that use words like bioidentical, efficacy and synergy then you’ve come to the right place.

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Declaration: The IAS Aging Matters™ magazine is intended for IAS private club members and focuses on the latest international nutritional, hormonal and drug therapies to help combat the signs of aging. These signs include the physical, mental and internal changes consisting of the diseases and disorders such as cancer, arthritis and senile dementias etc. However, the main focus is upon the prevention of such aging diseases and disorders for the ‘healthy-aging’ individual. Copyright 2014: All copyrights are acknowledged. Whilst every effort has been made to ensure accuracy, no responsibility can be accepted for illustrations, photographs, artwork or advertising materials while in transmission or with the publisher or their agents. Disclaimer: All educational information is offered under IAS terms and conditions. This information does not replace the advice of your physician and restrictions may apply in some countries. The opinions expressed by the writers may not be those of IAS or the magazine. All prices shown are in US Dollars and are for reference purposes only and they do not include taxes (where applicable), nor do they include shipping & handling fees. Prices, conditions and terms are subject to change without notice.

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be doing so. Who isn’t interested in how they are aging?” PM: “Let us start then with the 64 billion Dollar question! Please tell us what you believe aging to be.” WP: “In a nutshell, the pineal gland, via its links with the pituitary gland and the hypothalamus, is the biological clock network; it is a true scanner for growth, fertility, aging and also death.” PM: “So in-effect, the pineal gland acts as a daynight counter limiting our lifespan?” WP: “Yes, it seems blatantly obvious to me. Are we different from dogs, cats and mice? No, we are all mammals!”

The rotational origin of diseases and aging An interview with

Walter Pierpaoli, M.D., PhD. In this interview, the Editor of the Aging Matters™ magazine, Phil Micans (PM) interviews Walter Pierpaoli, M.D., Ph.D. (WP) Dr Pierpaoli is famous for his scientific and clinical published research into melatonin, the thymus, immunity and much more. In addition, he is also recognised for being one of the world’s foremost antiaging physicians. In this interview, Dr. Pierpaoli describes his latest work and how it impacts his ‘rotational theory of aging.’ PM: “Once again Dr Pierpaoli it is my pleasure to be talking with you on our favorite subjectaging! I know it is a subject that fascinates you, me and many of our readers.” WP: “Quite right Phil, as always it is a delight to 4

PM: “I think that an age-clock counter explains why there have only been a handful of people who have made it past 120-years of age. If it were, for example, just down to free radicals as the cause of aging, there should have been some numbers of persons with excellent free-radical scavenging activity who would have had significantly longer lifespans by now. My assumption is based on the estimates that there have been 128 Billion homosapiens who have lived on Earth- that’s stated on Wikipedia so it must be right!!! (Ha ha)” WP: “As you well know, I do not believe in the fairy tale of poisonous radicals. It is fashion in science, such as the other fairy tale, that you can prolong life by maintaining telomere length. It is a desperate attempt which makes me laugh. The body takes care of itself, if the central ‘clock’ is synchronized!” PM: “Of course many people know that lifespan averages are increasing worldwide; but this is the mean lifespan for the average person, the maximum lifespan doesn’t seem to have expanded much- if at all. Roman records suggest there were individuals living up to 120-years, even thousands of years ago.This maximum lifespan of 120 years is even recorded in the Bible.” WP: “What prevents man to live normally to 110, 120 or 130 years are diseases! Now today’s highly polluted environment facilitates all kind of diseases,

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which when combined with bad genetics is the main cause for atherosclerosis and tumours, which kill 80-90% of the population. New generations are now doomed to age earlier. In fact, the long-lived people are those born before 1950, before the environmental disaster. They were raised and grew up in a more pristine nature- it is my own generation. Longer and healthier life now is a lie and I can see it in children! Believe it or not, healthy children do not exist anymore!” PM: “So by understanding that the pineal can recognise day from night, by releasing melatonin during darkness, and that this action could be a counter, why is your theory of aging called the rotational theory?” WP: “It is time to explain planetary and atom rotational movements, all being in cyclicity etc. Everything in the cosmos is rotational and totally synchronized, from the atoms to the galaxies! Every cell in our body follows a strict circadian, day-night cyclicity, lunar and seasonal periodicity. We are generated, grow, procreate and follow our species program in a completely rotational system, controlled by our ‘clock’ in the hypothalamicpituitary-pineal network. We are a bunch of ‘tubes’ - arteries, gastrointestinal, urinary, etc., all strictly controlled by hormones, which in turn synchronically maintain cyclicity and periodicity, all linked to the rotational forces of the lunar-planetary system. After all, is the menstrual cycle different from the moon cycle? No it is not; but disruption of our adaptability to the rotational forces leads to diseases and early aging.” PM: “So can melatonin, when taken as a nighttime supplement, trick the age-clock? What have your animal experiments told you about their maximum lifespans and indeed the condition of their health in their later years?” WP: “Melatonin a precise night signal from the pineal gland; my murine experiments clearly illustrate that by ‘putting to rest’ the pineal gland, with night administration of melatonin, that the mice do not become immortal, but they do prolong their vitality which enables them to reach their maximum life-span, which is 3 years and would correspond to 110-130 years in man. It is simple and clear, with

melatonin, which protects the pineal gland, we can prevent the ravage of time afflicting our later years.” PM: “And how might this play out in humans in terms of lifespan and health?” WP: “I do believe that ‘resetting the pineal clock’ with melatonin, formulated in a way which produces and mimics the physiological night peak, we can enter a new phase of human life which allows all of us to reach our maximum lifespan in a useful way.” PM: “As a medical doctor I appreciate you have been treating many thousand of patients over decades, how have your patients’ health been improved by your protocols?” WP: “From the publication of the USA bestseller, ‘The Melatonin Miracle’ in 1995, I was almost forced by people and circumstances to apply my discoveries to patients. I verified my resynchronization method in several thousands of patients. All of them are cured from even the most hostile diseases such as cardiovascular; neurodegenerative a.o. Tumors can be easily prevented. I did not see a single case in my patients. A book is now being assembled collecting letters from the cured patients which is entitled; ‘The happy patients of Dr. Pierpaoli.’ Isn’t it the ultimate defiance?” PM: “I happen to know that your protocols include more than melatonin supplementation; can you describe some of your other fundamental approaches to optimal health please?” WP: “If the pineal gland controls our rotational adaptation to lunar and planetary cyclicity, obviously the night protection of the pineal gland with melatonin is fundamental. However, what will happen upon night protection of the pineal is a cascade of positive events which concern hormone inter-synchronization. In most cases I observe pituitary and thyroid dysfunctions, mostly hypothyroidism, which goes undetected owing to the laboratory assays which are totally misleading and wrong! I think this is a complete disaster. Clear or latent, insidious hypothyroidism is affecting 99% of the adult population. I do not know the reason for it and probably it is the main cause of pathologies in the new generations. But nobody talks of it! I

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developed my own parameters. For example, I keep TSH at zero and ‘free’ T3 with ‘free’ T4 two-three times higher! TSH is a carcinogenic polypeptide similar to prolactin, whose value should not exceed 10 ng/ml. But it is prolactin that is the most dangerous carcinogenic, tumor-promoting agent in men and women. Also, in the course of my studies, in 1989, I discovered some totally unexpected activities for TRH, which has the totally misleading name of thyrotropin-releasing hormone. I wish to tell its story in a book. In fact, my observations on TRH activities over the past 25 years, allow me to say that a different level of basic regulation exists in the body- which goes back to the origin of life. This tiny molecule occupies a fundamental role, including the regulation of insulin production and release and consequently the precise control of blood sugar!” PM: “Ah yes! TRH or thyrotropin releasing hormone; we did cover it in the lead story in Aging Matters™ issue 3, 2012 (copies of which are all online at: www.antiaging-systems.com/ antiaging-magazine) Perhaps I could ask if you could please do a quick recap of the beneficial properties of TRH?” WP: “My published experiments have shown that TRH may become a key molecule to invert the clock of aging. For example, it regenerates testicles in very old animals and also restores kidney function in sclerotic infiltrated kidneys. It seems to produce a regeneration of beta cells in the pancreas of diabetic animals. I am deeply interested to pursue clinical studies with TRH.” PM: “I appreciate that you like to refer to TRH, much like melatonin, not as a hormone, but as a life generating molecule, why is that?” WP: “The semantic attribution of ‘hormones’ to TRH and melatonin is an outrage to good sense and human intelligence. Both molecules are totally devoid of any side- or toxic effects even at huge concentration and even when given intravenously. In spite of this, European countries have waged a war against them, in particular Switzerland and Germany, obviously fearing their therapeutic activities when confronted by the profits generated by the industry of the chemical, man-made drugs.” 6

PM: “TRH is actually a tri-peptide and as many of our readers are aware, there is a wave of interest in the ways peptides work within the body now. So let us cut to the chase, after all, knowledge is worthless without power, or in this case - application. How do you recommend your patients use TRH, in terms of its dose and its timing?” WP: “With 20-years of studies at my disposal, I developed an elegant method to allow TRH to enter the blood stream. In fact, the fragile molecule cannot be given orally because it is rapidly destroyed in the stomach. Also its production costs are prohibitive. Thus I recommend sublingual tablets of 5 mg and 10 mg. This method allows a direct entrance to the blood stream via the sublingual, superficial venous plexus.” PM: “And does it need to be taken every day?” WP: “We do not really know if TRH follows a circadian rhythm. However, in some of my experiments I observed that TRH shows more pronounced effects when taken in the morning. I suggest cycles of TRH, 5 mg sublingual tablets for periods of one month, on and off. I also suggest some blood tests of glycemia and lipids regularly in order to ascertain its benefit. It is particularly rewarding for patients suffering from Metabolic Syndrome X.” PM: “And for melatonin, how should one take melatonin?” WP: “The real value of melatonin is its formulation which allows its night release between 1am and 3am. Many years ago I formulated melatonin with zinc and selenium; it is sold in Italy as Melatonin Zn Se® and by IAS as MZS™. After many scientific studies showing how melatonin can dramatically enhance zinc levels, whose concentration in blood notoriously decreases with aging, it was the combination of melatonin with zinc and then particular excipients- that also determine a night peak- that have created this true biological bomb! One must know that zinc is a basic mineral for synthesis of more than 200 enzymes. One tablet at bedtime between 9pm and 11pm is proper. The dosage of 3 mg is suggested, some may require less,

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some may require more.” PM: “And are there any particular times to take melatonin?” WP: “One should try to emulate the night peak; this means that nature has determined that melatonin levels are highest between the hours of 1am and 3am. The MZS™ when taken between 9pm and 11pm releases the melatonin into the blood during the period of 1am and 3am, therefore inducing this same as nature response.” PM: “I have to say, that we here at IAS like original products, after all they are the ones that achieved the original results in the clinical studies- the results that the copycats will allude to! I know that your MZS™ works well because I’ve seen it in patients time and again. Even on those who were going to give up on melatonin because they had seen no benefit with the generic they had been using; as is often said in pharmacology, the devil is in the detail!” WP: “Exactly Phil. Many people probably do not realise that many of the clinical melatonin studies have used our brand. For example, a study published in the New York Academy of Sciences in 2005 showed that our MZS™ can reverse both wet and dry versions of macular degeneration- can you imagine! Yet how many people are aware of this fact?” PM: “Quite true, my joke is that if you want to keep something a secret - publish it! (Ha ha) After all, who can read everything? This fact and the pressures on doctors’ time, means that many rely on the pharmaceutical rep to keep them appraised of developments. Accordingly, they only hear what the drug companies are selling. Still, let us not dwell on this negativity; please tell us a bit about your latest projects.”

I do to achieve such good outcomes. Right now, I have 1000 patients, none of them have cancer or heart disease or dementia- can you imagine?” PM: “Excellent news! In the meantime, by the time folks read this interview, we should have your eBook ‘melatonin, the key of life’ available for download.” WP: “I hope that will be helpful to people. I would like to make a statement about why it is vital to talk directly to the public.” PM: “Please go ahead.” WP: “A revolution can only be started by the people themselves, from the ground-up. Once the public wake up to the current medical mafia and understand what is truly possible with alternatives, by which I mean non-orthodox, but nonetheless scientifically proven approaches; then the world of health will become a very different place.” PM: “Amen to that. I know many will enjoy hearing from you again Dr Pierpaoli, thank you very much for all your valuable time today.” WP: “I always have time for you Phil and all the great people at IAS.”

FREE eBook for every reader

Get Your FREE Dr Pierpaoli eBook Readers of Aging Matters Magazine can download a FREE copy of the revised and extended edition of Dr Walter Pierpaoli’s book ‘The Key of Life’, simply visit: www.antiaging-systems.com/ key-of-life-ebook and the download will begin automatically.

WP: “Right now Phil, I am working on two new books. One will describe TRH in detail– this is because the effects of TRH are both important and impressive, yet hardly anyone is aware of this news today. The second book will have examples of my patients, their before-and-after results and what was done in-between. I am writing that one, not because of my ego, but because I am so often asked what 7

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happened to beloved comedian George Burns, who slipped and fell fatally in his bathtub at age 97 years. Also unfortunate is the fact that most medical doctors do not know how to prevent bathroom falls. Contrary to what many people believe, an expensive medical insurance plan will not save them from many of the medical and lifestyle problems encountered during aging or from the diseases of aging!

Only Anti-Aging Medicine Solves Many Problems of Aging

Avoiding a hospital Bed by Dr. Richard Lippman My biochemist friend and patient, Bob, phoned me recently. In an urgent voice, he requested an immediate appointment. I was a bit surprised because several times previously he wanted to use only his traditional physician, who was covered by his medical insurance. I made the appointment for the following afternoon, wondering why Bob suddenly wanted my help. The next day, Bob arrived in my office, flustered and haggard from lack of sleep. He explained that several of his senior friends had passed away in recent months; one of them had fallen in the bathroom at night and was sent to the hospital with head trauma. Apparently, this poor fellow had fallen because of adverse reactions to prescription medications—an all-too-common occurrence among America’s seniors. Unfortunately, the same thing

Bob was also at risk from falling in the bathroom at night, and he asked me for a remedy. I explained to him that the answer is simple and straightforward: First, hire a carpenter for one day and have him install around the toilet and bathtub/shower areas stainless-steel 3-inch thick railings, which are available at most hardware stores. He would then be able to grab hold of these railings when he feels faint or off balance. He may also use them as additional towel or wet-clothing racks. These attractive 3-inch thick railings will fit neatly and aesthetically into any bathroom with the help of an experienced carpenter. However, they do need to be firmly attached to the framing in the walls with heavy stainless-steel screws. Also, one should have the carpenter lay down ‘anti-slip strips’ on the shower, bathtub, and bathroom floors. Second, I advised Bob to spray his nose nightly at bedtime with one dose of Minirin® or VASOPRO™ nasal sprays. These remedies will reduce the urge to urinate and limit the need for nocturnal visits to the bathroom. Third, Bob should purchase from IAS their advanced formulated melatonin MZS™ (melatonin Zn-Se) prescribed by the famous Swiss professor Walter Pierpaoli. Melatonin MZS™ helps most people sleep better and attain a more restful REM sleep. Last, Bob explained that during nocturnal hours he sometimes stumbles on the bathroom mats. I advised him to remove these mats and, if the floor is slippery, replace them with anti-slip strips or even replace the floor tiles with slate. Unlike tile, marble, and other floor materials, slate does not become slippery and dangerous when wet! Therefore, it is ideal for older

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people who are at risk of falling in the bathroom. Bob thanked me for my help and promised to report to me the results from my suggested lifestyle changes. As you can see from the above case study, preventative and anti-aging medicine offers more advanced and cutting-edge solutions for common problems encountered during aging.

Lower High Blood Pressure Naturally

In the foregoing study, Bob has high blood pressure (bp), and he consumes bp-lowering medications that cause him to become dizzy and disoriented and lose his sense of balance. This is a common tragedy for modern American medicine and there should be better solutions. There are better solutions, but many remain unknown to medical practitioners. Upon gaining Bob’s confidence in the quality of my advice, I persuaded him that the underlying cause of his high bp is a loss of hormones as he aged. This phenomenon is especially true for those over age 50 years, but it even plagues some people much younger. In Bob’s case, I encouraged him to take comprehensive blood and urine tests. These tests confirmed my visual observations: Bob was deficient in the hormones DHEA, cortisol, thyroid, growth hormone, and testosterone. The first two—DHEA and cortisol—were visually apparent, as depicted in the following younger-toolder photos of GOP Speaker of the House John Boehner.

Figure 2. House Speaker John Boehner progressively aging.

Observe that because of aging, Mr. Boehner’s adrenal glands produce lower and lower amounts of vital hormones such as DHEA, cortisol, and 10

aldosterone. These adverse effects are evidenced by dark circles around his sunken eyes. Mr. Boehner, my patient Bob, and many others would benefit from daily supplements of hydrocortisone and DHEA. These dark circles and sunken eyes will all but disappear when one consumes these corrective hormones combined with a healthier diet—in other words, no junk food. These combined remedies cause the dark-circled pigmentation to disappear and will push forward the eyes in their sockets as gains are made in laying down new and healthy collagen and elastin. This simple remedy results in true regenerative medicine as practiced by knowledgeable anti-aging physicians during the past decade. Indeed, my own dark eye circles disappeared after about three months of daily DHEA treatment. My sunken eyes pushed forward in their orbitals (sockets) after about a year of treatment! Also, notice the jowls Mr. Boehner acquired as he grew older. This aging sign is often referred to as ‘myxedema.’ Historically, men hid it by growing long beards. Today, we can prevent it with daily doses of growth hormone (or a growth hormone releasing peptide like Releasing-PRO™) and a natural thyroid like Armour® over a treatment period of approximately three years. I believe that correcting with Armour® thyroid is worthwhile for more than aesthetic reasons: I strongly recommend this option because untreated thyroid deficiency will result in an approximate 43% increase in the risk of dying! On the other hand, for aesthetic reasons, if you insist upon an immediate fix for myxedema, I strongly recommend the dermatological filler called ‘Radiesse®.’ It contains the completely natural substance hydroxyapatite, and skilled dermatologists inject it below the skin and often against the bones of the face. A dermatologist will make this procedure virtually painless by first numbing the face with lidocaine cream. This treatment lasts for about a year and provides an instant straightening of the jawline—much to the amazement of many laymen. Radiesse® also treats sunken high cheekbones caused by collagen loss (corrected by hGH or Releasing-PRO™) plus insulin growth factor 1 [IGF-1]) and osteopenia (caused by bone loss). A highly experienced and artistic dermatologist must judge the exact positioning and depth of the filler for

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best aesthetic results. A second quick fix is to spray your nose weekly with MSH2-PRO™. This will completely and naturally increase the tanning of your skin without damaging your skin with sunlight. In summary, I strongly encourage both short- and long-term remedies for significant improvements in skin coloring and facial structuring and appearance.

A Delicate Dance of Hormones

You may have noticed that Bob might need up to five different hormones supplemented in his daily diet for improved health and slowed aging. Multiple hormone deficiencies need to be corrected because all hormones work together in a concerted fashion and they do a ‘delicate dance’ with one another for optimal health benefits. This delicate dance occurs naturally and without medical intervention in our youth, but it often stumbles as we approach middle age. The foremost example of this multiple hormone loss is found in women. On average, women stop ovulating at age 41 and experience hot flashes, dry skin, headaches, cranky moods, etc. When their gynecologists provide them with natural bioidentical estradiol (Esnatri™ cream) combined with natural bio-identical progesterone (Progest-Pro™) creams, these adverse symptoms subside (and the risk of cancer also diminishes).

lies with Mother Nature’s incredible ability to balance our hormones in a delicate dance with one another during our youth! This delicate dance and balance can be restored to us older folk by correcting with low-dose natural and bio-identical hormones as prescribed by Dr. Thierry Hertoghe in his many lectures and books.1 This balance encourages a lean and youthful body and nimble brain and avoids weight gain and the diseases of aging.

The Amazing Actions of Balanced Hormones that Focus on Improving Our Health Issues

Some hormones such as Armour® thyroid positively impact every cell in the body by restoring cell metabolism and output (homeostasis). Other hormones are more focused. For example, aldosterone (and fludrocortisone) improves kidney retention of water and salt and acts on the innerear cochlea to improve hearing by up to 30 or 40 decibels in aldosterone-deficient patients. Unlike many prescription drugs, these more natural hormone remedies significantly improve our health and appearance without nasty side effects.

The Delicate Dancing of Hormones The hormone progesterone (Progest-Pro™) offsets the negative effects of the hormone estradiol (Esnatri™ cream), especially regarding hyperplasia (excessive cell growth) in the tissues of the breasts, ovaries, and prostate. Thus, these two hormones delicately dance with and balance each other. This promotes healthy and youthful breasts, ovaries, and prostates without deleterious side effects such as excessive cell replication and cancer. This would not be the case if either one of these hormones were deficient.

Indeed, if you have ever wondered as I have, how teenagers and twenty-something’s can consume large quantities of junk food and mostly retain hard muscles—especially hard and round buttocks and breasts and a firm, non-sagging face—the answer

Figure 3: The brain acts as a top manager or overseer in directing most hormone activities in the body.

Top-Manager Hormones Direct the Body

The brain uses top managers or overseers to produce hormones that direct their actions in our cells. The bloodstream carries hormones to all our cells. The hormones penetrate deep into our DNA, turning off

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or on our genes. Upon arriving at this genetic level, these hormones assert command and control of key biochemical processes. These key hormones and their helper proteins are human growth hormone (hGH or its stimulator, Releasing-PRO™), IGF1, and TRH (pineal gland proteins). These three dominate at the top of the heap in directing a symphony of cellular processes throughout the body. These critical hormones and their helper proteins slowly mold and sculpt our bodies to a more youthful appearance and help us maintain a quick, firm, and more resolute-thinking brain. My colleagues and I have conducted studies where patients consumed Releasing-PRO™ four times daily. We found that IGF-1 doubles from approximately 70 to 160 (plus or minus 15 ng/ml blood). This 160 level of IGF-1 will direct and sculpt the body to a more youthful appearance, as depicted below. In summary, low-dose, bio-identical hormones will cause our thinking to become increasingly firm and resolute and make our bodies more shapely and sculpted, even if our daily exercise is marginal*.

Conclusions

Many of the problems of aging can be corrected by making constructive changes to our living quarters and by supplementing with key hormones and peptides. People who desire better control of their health and aging find great value in what IAS has to offer. My colleagues and I use IAS products to enhance longevity, appearance, brain activity and health. _____________________________ *Footnote: However, optimal results are achievable only if one is willing to exercise religiously one hour daily along with using hGH and IGF-1 therapies according to Dr. Thierry Hertoghe’s The Hormone Handbook.1 Seven to eight hours sound sleep is also critical since recent research (2) has indicated that during sleep the brain flushes out cellular waste, especially beta-amyloid, a key component that accumulates in aging brains and Alzheimer’s disease. Nearly all centenarians when autopsied show significant accumulation of beta-amyloid.

References

1. Hertoghe, T. (2010). The Hormone Handbook, Vol. 2, Surrey, England: International Medical Pub. 2. Lulu, Xie, et. Al. (2013) Science, Vol. 342 no. 6156, pp. 373377.

Figure 4: Before-and-after photos of hormone body sculpting.

2030’s Anti-Aging Medicine Knowledgeable computer scientists and the Gerontology Research Group in Los Angeles have predicted that scientists will be able to reprogram our epigenomes (DNA) in the 2030’s, thus eliminating genetic defects at birth as well as those defects caused by aging.

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Releasing-Pro™ contains Growth Hormone Releasing Peptide number six (GHRP6) and represents the very latest development in Ghrelin the appetite regulating hormone. GHRP6 stimulates the body’s own growth hormone production and increases IGF-1 levels which boosts muscle, reduces fat and improves endurance. Releasing-Pro is available in a nasal spray, a unique method of introduction that is second only to injections in terms of its effect on blood levels of IGF-1.

5 ml 500 IU nasal spray (10 IU per spray) $79.99* *Restrictions may apply in some countries. All information is educational and does not replace your physician and is subject to IAS terms and conditions which may change without notice.

and stimulates the production of collagen in the skin. HA also keeps skin elastic and protects joints from repeated stresses. HA itself has a short lifespan and the body must be produce it each day to maintain the levels necessary for the repair and regeneration of tissues lost through wear and tear.

HA is continuously synthesised in the body by a class of membrane enzymes called hyaluronan synthases which lengthen HA by repeatedly adding glucuronic acid and N-acetylglucosamine to the nascent polysaccharide molecule. In the reverse process, HA is broken down by enzymes called hyaluronidases into oligosaccharides and very low molecular weight HA (which exhibit pro-angiogenic properties forming new blood vessels), which is important in the tissue healing process.

Hyaluronic Acid nature’s moisturizer By Howard Thomas, Ph.D. Hyaluronic acid (HA) has been called “Nature’s Moisturizer.” It is found throughout the body because it forms part of the structural tissue that holds tissues together. HA is a fundamental component of the extracellular matrix; it occupies the areas between cells and almost half (7.5 grams) of HA within the body is located in the collagen of skin, acting as a moisture retaining gel. It is found in many tissues in the body including the heart, eyes (vitreous humour), joints (synovial fluid), tendons and ligaments. Scientific studies have shown that HA improves skin and tissue hydration; works as a free radical scavenger 14

HA is a common ingredient in many skin care products especially those that claim to make the skin look younger and banish wrinkles. In 2003, the FDA approved the use of HA injections for filling soft tissue defects such as facial wrinkles. These injections, which have become very popular, temporarily smooth wrinkles by adding volume under the skin. These effects may typically last 4-6 months.

As we age the production of HA in the body decreases. Fibroblasts, which produce collagen, elastin and fibronectin to provide strength, structure and elasticity to the skin, slowdown and become less active and produce less HA. As HA levels become depleted, collagen fibres bind together into more rigid fibres known as Collagen Type-I leading to older facial looks. Increasing the HA levels by supplementation can promote Collagen Type-II which provides for a more youthful facial appearance.

“HA is a common ingredient in many skin care products especially those that claim to make the skin look younger and banish wrinkles.”

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The unique viscous nature of HA and the fact that it does not stimulate immune or allergic responses and is extremely well tolerated in the body, has led to its use in a number of clinical applications, including the treatment of osteoarthritis and associated joint problems, (Puhl W et al Ann.Rheum Dis 56(7); 637-40); as a surgical aid in eye surgery, (Miller D et al “A comprehensive guide to its use in Ophthalmic Surgery”. J Wiley NY 1983); and as an essential stimulator of the healing process and tissue regeneration in burns and surgical wounds, (J Chem/G Abatangelo,Wound Repair and Regeneration,1999,7:79-89); plus the treatment of Gingivitis/Periodontitis, (R Moseley et al Dental Update 2002 vol 29 no 3); and for Apthous (mouth) ulcers, (Nolan A et al Oral Pathol Med 2006;35:461-5); Lichen Planus, Venous Ulcers, etc.

Our joints are surrounded by a membrane called the synovial membrane which forms a protective capsule around the ends of the bones. This membrane secretes synovial fluid which serves as a lubricant, shock absorber and nutrient carrier. Cartilage is immersed in the synovial fluid and is avascular, meaning it contains no blood vessels. All the nutrients needed by the cartilage are provided by the synovial fluid. Hyaline cartilage is the most predominant form of cartilage and it lends strength and flexibility to the body. A key component of cartilage is HA. The synovial fluid in the joint capsule has important functions:

• It protects the cartilage covering the bones from excessive wear and tear by keeping them slightly apart. • Its viscoelasticity protects the cartilage against shock.

• It lubricates the joints and prevents bones rubbing against each other.

• It provides water and nutrients to cartilage and eliminates waste products.

As we age and thus produce less HA, so the viscoelasticity of the synovial fluid is markedly reduced. This change decreases its lubricating and shock absorbing functions. In turn, this increases mechanical loading of the joint and cartilage destruction, which ultimately results in pain and restricted mobility of the affected joints. Glucosamine has been widely used as a supplement for joint problems with good results. In vitro studies using cells in culture show glucosamine functions by stimulating HA production in the synovial fluid and by fibroblasts. So taking HA as a supplement gives faster and more reliable results than glucosamine.

HA has been given by intra articular injections for osteoarthritis for many years with good success, but the injections can be painful, have to be repeated and are costly.

HA supplements in tablet or capsule form have been available for some time; however the quality of the HA varies enormously. Some tablets/ capsules have low grade HA and poor absorption in the gut.

A major breakthrough has been the development of a liquid formulation of HA which is rapidly absorbed in the gut and appears in the joints in less than sixty minutes and it remains in the joints for at least five hours reducing pain and improving joint lubrication and mobility. (J. Agric. Food Chem.2008, 56, 10582-10593). This proven effective liquid version of HA (taken by mouth), is known as Novisyn® and is now available from IAS.

“HA supplements in tablet or capsule form have been available for some time; however the quality of the HA varies enormously.”

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Novisyn Introducing

A Faster Acting and More Powerful Supplement Than Glucosamine

• Naturally helps joint mobility • Single, pre-measured daily dose • No painful injections • No side eﬀects Novisyn is an oral supplement, supplied in pre-measured daily doses. It is absorbed into the body within a few hours and the beneﬁts of reduced joint discomfort can be felt within a few days.

As endorsed by Gary Wolstenholme MBE, English Pro Golfer “Walking for several miles a day around a golf course obviously takes its toll on the body; joint pain is something I have suﬀered from frequently throughout my career. Taking Novisyn as a daily supplement has been great for maintaining my joint mobility and I would highly recommend them to anyone who wants to remain active”.

Muscles Synovial ﬂuid within Synovial cavity

Joint capsule and synovial membrane Cartilage

Bone

*Restrictions may apply in some countries. All information is educational and does not replace your physician and is subject to IAS terms and conditions which may change without notice.

Novisyn (hyaluronic acid) 30 x 5ml liquid Sachets $25.99

Dr Ward Dean answers your questions

We are delighted that Ward Dean, M.D., one of the world’s foremost antiaging physicians, has agreed to answer our readers’ questions. Full details about Dr. Dean can be seen at his website: www.warddeanmd.com

Dear Dr. Dean Q. “I am most interested in the glycation theory of aging- whereby because of proteins cross-linking they become impaired etc. I am a 50 year old male who has been tested by BioCLIP™ and found to have hardening of the arteries. I also have mild cataracts and a potential pre-diabetic (type-II) development, (hence my interest in this theory!) Please advise me on any suitable strategies to reduce my glycated blood load.”

graph films was due to the cross-linking of protein molecules, which Bjorksten believed was also the cause of aging in humans. This was confirmed in a crude way by comparing the similarity between the shape of the mortality curve for humans (Fig. 1) with

MORTALITY 20,000 16,000 14,000 12,000

B.A., Oregon

10,000

A. Dear B.A.,

8,000

The glycation theory of aging is a modern outgrowth of the venerable cross-linking theory of aging, first proposed by Johan Bjorksten in 1942.1,2 Bjorksten was a chemist from Finland, who earned his Ph.D. degree at the University of Wisconsin in 1937. He went to work for the Ditto Corporation of America, which was the ‘Xerox’ of the day.

6,000

Protein cross-linking as cause of aging While at Ditto Corporation, one of the main problems Bjorksten faced was to develop a way to increase the ability of the Hectograph films to withstand summer temperatures, exposure to water, mechanical stretching and friction, and to prevent their drying out and cracking. The ‘aging’ of hecto-

4,000 2,000 0

20-25

40-45

60-65

AGE

80-85

+ YEARS

Fig. 1. Mortality rate plotted against time for white American males.3

a viscosity curve of gelatin during a cross-linking reaction (Fig. 2).3,4 The crosslinkage theory stated that the principal cause of aging was the linking together of two or more large molecules (macromolecules), which progressively linked with other molecules, impairing the functioning of cells, tissues, and organs, resulting in the aging of the organism.

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900 800 700

JOHAN BJORKSTEN & FRED ANDREWS

Cross-Linking Of Gelatin Measured with Brabender Plastograph Composition Gelatin - 20% Tanolin - 3% pH - 3.3 Conditions Temperature - 45°C Lever ratio - 1:1 RPM 50

600 500 400 300 200 100 0

TIME IN MINUTES

Fig. 2. Rate of progressive cross-linking of gelatin.4

Search for cross-linkage inhibitors Bjorksten focused on a potential means of preventing and breaking up crosslinkages by using chelating agents that attach to metals within the body, enabling them to be excreted. Ethylene-diamine-tetra-acetic acid (EDTA) is a synthetic amino acid that removes metal-based crosslinkages by chelation, thereby “depolymerizing the gerogenic aggregates.” 5 Chelating agents in current clinical practice besides EDTA (approved for use in the treatment of lead poisoning) are deferoxamine (Desferal® for acute iron intoxication), and DMSA (used to treat lead and mercury intoxication). Physician members of the American College for Advancement in Medicine (ACAM) are proponents of intravenous chelation therapy with EDTA as a treatment for many chronic degenerative diseases, like atherosclerosis, hypertension, diabetes, and Alzheimer’s disease.6 Chelation with oral EDTA chelation is also becoming more widely used. [Ed. - EDTA is available in BCI®, Beyond Clean 2® and Beyond Fiber®] Other natural chelators include garlic, 7 chlorella, 8 lactic acid, citric acid, and malic acid. Bjorksten demonstrated that lithium was also an effective aluminum chelator and crosslinkage inhibitor, stating that “lithium continues to be the most effective electrolyte for aluminum detachment.” 9 [Ed. – Lithium orotate is available from IAS] Chelators as life-extending substances A number of studies confirm that chelating agents, particularly, EDTA — may have life-extending properties. Scientists demonstrated the life-extending effects of EDTA on lowly rotifers (small multi-celled 18

animals found in freshwater lakes and ponds).10-14 In the Soviet Union in the 1970s, Dr. T.L. Dubina performed a series of studies with EDTA on the life span of rats. In most of the studies, the mean life span of female rats treated with EDTA was increased by nearly 50%, and in one study the maximum lifespan increased 18-25% over the control animals. 15 Aluminum—a powerful cross-linker Aluminum is a highly reactive metal that occurs freely in nature, and comprises over 8% of the earth’s crust. Although it also occurs very widely in human nutrition, (most people ingest 10-100 mg of aluminum daily), it does not play a role in any known metabolic process. Aluminum is highly toxic, even in extremely small amounts, and although the neurotoxic effects of aluminum have been known for many years,16 scientists have recently shown that aluminum accumulation may contribute to Parkinson’s disease17 Down’s syndrome18 and Alzheimer’s disease.19 Aluminum uptake increases with age In 1955, during a talk on gelatin crosslinkages and aging at the Gerontological Society in Baltimore, Bjorksten discussed the relationship of aluminum to crosslinking. One of the attendees, Prof. H.H. Zinsser of Columbia University, was so interested in the concept that he and Bjorksten began a fruitful collaboration that was to last for seven years. Using spectrographic analysis, they examined the aluminum content of 84 persons, ranging in age from 10 to 90 years (Fig. 3).

mGm 100 Gm 10.0

Aluminum concentration versus increasing age in aortic tissue

DEATH

mGm 100 Gm 10.0

ALUMINUM

SCALE READING

1.0 ALUMINUM

1.0 0.0

20 30 40 50 60 70 80

0.0

Fig. 3. Aluminium concentration versus increasing age in aortic tissue. Bjorksten, J. The crosslinking reaction in relation to aging, Life Chemistry Reports, 1988, 6:367-385.

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.90 .75

EXTRAPOLATION

ug/g AI WET BRAIN BASIS

BRAIN ALUMINUM CONCENTRATION AS A FUNCTION OF AGE

.60 .45 .30 .15

AGE

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The first five columns are based on the Markesbery, Ehmann, Alauddin, Hossain “Brain trace element concentrations in aging” Neurobiol. Aging 5:19-28;1984. Extrapolation by Johan Bkorksten, Ph. D.

Fig. 4. Brain aluminium concentrations as a function of age. Bjorksten, J. The role of aluminium and age dependent decline, Environmental Health Perspectives. 1989, 31, 241-242.

Bjorksten concluded that the progressive increases of aluminum with age were of great importance, and believed that the aluminum mechanism alone would limit human lifespan to 110-120 years of age even if no other cause of death intervened.22 Preventing aluminum accumulation and crosslinking Bjorksten and his staff evaluated the ability of chelating agents to remove aluminum-containing stains from the aortas of 5-6 month-old hogs (Fig. 5).23 it can be seen that EDTA was the most effective. Lactic acid, similar to blood concentrations generated by exercise were moderately effective. Of interest was the fact that 0.5 % procaine—the active ingredient of Gerovital® (or GH3, the Romanian antiaging drug)—was also moderately effective in reducing the aluminum. This raises the question whether the metabolites of GH3—DMAE and PABA—might also have some effect in this regard.24 In fact, Drs. Imre Zs.-Nagy and Katalin Nagy demonstrated that both dimethylaminoethanol (DMAE) and centrophenoxine (CPH) are indeed able to diminish the extent of crosslinking in old rats.25

[Ed. – Original Gerovital-H3® and generic GH3-Pro® are available, as is centrophenoxine as Cent-Pro®] 0.2% PROCAINE X BLANK 0.5% PROCAINE 0.2% LACTATE MICROGRAMS ALUMINUM PER DISK

They found peak levels at age 40-50, followed by a drop and then leveling off, indicating that those whose aluminum accumulation peaked in middle age most likely did not survive the next ten years. 20 Zinsser’s data were confirmed independently by scientists who demonstrated a progressive increase of aluminum concentrations in the brain (Fig. 4).21

160

120

X 0.2% LACTATE; 0.5% PROCAINE 0.01% DESFERAL

0.01% EDTA; 0.05% DESFERAL

40 0 0

BLANK

NUMBER OF EXTRACTIONS

Fig. 5. Comparison of the ability of various chelating agents to remove aluminium from hog aorta. Schenk, R.U., Bjorksten, J., Lipert, R., Mortell, M. Extraction of aluminium from aorta tissues by chelating agents and lactic acid. Rejuvenation, 1981, VIII, 1, 4-10.

Bjorksten’s team also evaluated the ability of various concentrations of lithium to remove tightly bound aluminum from tanned leather baseball covers.26, 27 Using a 0.05M concentration of lithium citrate, they completely demetalized the leather in approximately three months. Lithium is used clinically to treat manic depressive illness (MDI). Recent studies indicate that it may offer benefit in the prevention and treatment of Alzheimer’s disease, as well. 28 Perhaps long-term treatments with low doses of lithium may be an effective way to displace crosslinked/ protein bound aluminum in animals and humans. Lithium orotate as a dietary supplement is the safest, most effective form of lithium available. Bjorksten spent his entire career searching for the cause and cure of crosslinks, which he believed would result in the reversal of aging and maintenance of prolonged youth. He believed that one cause of the crosslinks was heavy metal poisoning, (especially aluminum), which could be prevented and reversed with chelation therapy. He also identified the loss of fluidity of cell membranes as a contributing factor, and supported the use of membrane fluidizers such as centrophenoxine, phosphatidylserine, choline and lecithin. Advanced Glycation End Products of Aging (AGEs) In 1965, Dr. H.B. Bensusan proposed that a process known as the Maillard reaction, (the non-enzymatic

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Time:

Hours

Days

Weeks, Months

The Amadori product further degrades irreversibly into a number of highly reactive carbonyl (C=O) compounds called Advanced Glycation End products, designated by the acronym AGE.32 AGE is a clever pun which reflects the proposed relationship of these reactive substances to aging and age-related diseases. AGEs can further react with other fats, proteins and nucleic acids to form largely indissoluble crosslinks. The age-related accumulation of these AGE products has been demonstrated in many tissues of the body (Fig. 7).33

mmol CML/mol Lysine

chemical reactions between proteins and carbohydrates that cause cooked foods to turn brown) was what caused all long-lived proteins in the body to turn brown and become fluorescent, (under UV light), become more cross-linked, less soluble, less elastic, and less digestible by enzymes. In 1985, Monnier, Kohn and Cerami provided further details of the role of the Maillard reaction,1 and further developed the idea that the Maillard reaction causes premature aging and degenerative diseases such as diabetes and heart disease.29 In this regard, many scientists think the human body may be viewed as a ‘low temperature oven’ with a relatively long—approximately 75 year —‘cooking cycle.’30 The Maillard reaction involves a chemical reaction between a sugar with a protein, into a complex known as a Schiff base. With continued exposure to the sugar, the Schiff base undergoes a ‘rearrangement’ known as non-enzymatic glycosylation that results in a more stable, less reversible substance, known as an Amadori product. In the human body, this process reaches equilibrium over several weeks (Fig. 6).31

( )Lens Proteins ( )Skin Collagen

8 6 4 2 0

100

Age (years) Glucose + NH2-R

Protein lysines Schiff base

Schiff Base

Wolff pathway

C2 H H OH [O2] P-N=C-C +H2O Nam + iki H C1 [O2] C2 Dicarbonyls HHO P-N-C-C H E1

C2 F

Advanced Glycosylation Endproducts

Fig. 7. Increased accumulation of AGEs (carboxymethyllysine [CML]) with age in human lens protein and skin collagen.32

P-NH2 + SUGAR

Amadori product

Protein Cross-links

Amadori Product

C2 [O ] 2

H=O

Crosslinkage Theory Gets New Life

H=O

Bjorksten was a talented petroleum chemist. Had he been a food chemist instead, he may have appreciated this link between the Maillard Reaction and crosslinking much earlier, and made even greater progress in developing preventive and therapeutic approaches to crosslinkage-induced aging. Through their insightful work in understanding this process, scientists like Brownlee, Cerami and Monnier provided renewed impetus and a ‘rebirth’ for the crosslinkage theory. Unfortunately, they did this with little attribution to Bjorksten, who had doggedly pursued this approach to aging for over 50 years.

D C1

[O2]

Non-Fluorescent AGEs CML

Pentosidine Fluorescent AGEs

Fig, 6. Pathway of advanced glycosylation, from Schiff bases to AGEs over time. 31

During long-term hyperglycemia (elevated blood sugar), as in diabetics, glycation and AGE formation may be quadrupled! This explains why diabetics suffer the premature onset of a wide range of age-related complications including cataracts, retinopathy, neuropathy, nephropathy, atherosclerosis and osteoporosis.34, 35

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There are a number of substances that have been used to delay and reverse glycation-induced crosslinkages (AGEs). Khalifah and his colleagues proposed a schematic of the formation of AGEs, and illustrates a number of specific therapeutic targets (Fig.8).31 Schiff Bases

Type B inhibitors

Protein Type A inhibitors

Block formation of Crosslinks 1. Metformin 2. Aminoguanidine

Prevent Sugar Attachment 1. Pyridoxical-5-phosphate 2. Aspirin

Reactive Intermediates

Type C1 inhibitors Chelating Agents 1. EDTA 2. Penicillamine

Type C1 inhibitors Antioxidants 1. Vitamin C 2. Vitamin E 3. Lipoic Acid

Type D inhibitors Trap Reactive Carbonyl Intermediates 1. Metformin 2. Aminoguanidine 3. Carnosine 4. L-Arginine

AGE

Advanced Glycation Endproducts

200

Amadori Products Type E inhibitors

Prevent Formation of AGEs from Amidori Products 1. Metformin 2. Aminoguanidine

Type F inhibitors

Crosslinkage and AGE Breakers that can break crosslinks after they form 1. ALT-711 2. Phanacylthiazolium bromide (PTB)

Fig. 8. Schematic of Maillard Reactions and potential sites of intervention.31

Metformin (Glucophage®): Metformin is an anti-diabetic biguanide that was derived from the herb, Goat’s rue (Galega officinalis). Biguanide drugs were recognized by Prof. Vladimir Dilman as early as the mid-1970s as the most effective antiaging drugs in existence. Metformin is an insulin receptor sensitizer, capable primarily of lowering blood sugar and insulin. Dilman also demonstrated that biguanides restored cortisol receptor sensitivity. Metformin has many other beneficial properties, including optimizing lipid profile, reducing body fat, maintaining levels of growth hormone, stimulating immunity, and extending the maximum lifespan of experimental animals.36 Aminoguanidine (Pimegedine): Aminoguanidine is a substance that has been known for over 100 years. It is structurally very similar to guanidine, the active ingredient in the herb, Goat’s rue (the herbal prototype for metformin). Aminoguanidine has aroused a great deal of interest in the last twenty years, due to its demonstrated ability to block the formation of AGEs and AGE-induced crosslinkages in both animal and human clinical studies. Aminoguanidine inhibits AGE formation, preventing AGE-induced crosslinks in collagen and other tissues. Fortunately,

Acellular capillaries (per mm2)

+glucose

aminoguanidine does not interfere with the formation of normal collagen crosslinks, which are required for structural integrity. Another mechanism by which aminoguanidine is believed to act is by enhancing the action of nitric oxide (the same mechanism by which Viagra functions).37, 38 Aminoguanidine also reduces the formation of lipofuscin (age pigment) and prevents or reduces cataracts, atherosclerosis, diabetic retinopathy, nephropathy and neuropathy (Fig. 9). 30, 39-41 A

0.20

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AGE Breakers (and inhibitors)

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Diabetic

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Non-Diabetic

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Diabetic + Aminoguanidine

Fig. 9. Effect of aminoguanidine on prevention of structural abnormalities of long-term diabetics in the eye (retina) and kidney (glomerulus).40

In a study of diabetic patients, after four weeks of therapy with aminoguanidine, LDL cholesterol decreased almost 30%, and total cholesterol and triglycerides both decreased almost 20%. Hemoglobin-AGE levels, a circulating marker of the degree of glycosylation, also decreased dramatically (13.8 U/ mg Hb at the beginning of therapy, to 10.0 U/mg Hb after only four weeks).42 Aminoguanidine is very safe, as indicated by short-term human studies which used the astronomical dose of 1200 mg daily.43 (This is in comparison with a usual human dose of 100300 mg daily). The dose required to cause death in half the animals (mice) to which it was administered (Lethal Dose 50 [LD50]) was 1800 mg/kg.37 That would be equivalent to a human dose of almost 300 grams! Pyridoxal-5-Phosphate (P5P): P5P, the active form of vitamin B6, has been found to significantly reduce the non-enzymatic glycosylation (formation of AGEs) of bovine serum albumin (BSA) with radioactive-labeled sugar. Of the substances tested, P5P

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was exceeded only by aminoguanidine in its ability to inhibit AGE formation (Fig. 10). Combining P5P with metformin or aminoguanidine may enhance their AGE-inhibiting actions even more.44

Inhibitor Concentration (mM)

Control

Ascorbate

DHA

5 0.1 0.5

Pyridoxal

5 0.1

Pyridoxal-5phosphate

0.5 5 5

Aminoguanidine 0

60 % labeling

100

Fig. 10. In vitro (“test tube”) test comparing the formation AGEs on bovine serum albumin when exposed to glucose. Note the dramatic reductions when aminoguanidine or piridoxal-5-phospate (P5P) are added.43

Vitamin B1 (Thiamine) and Benfotiamine: In their book, Life Extension, Durk Pearson and Sandy Shaw reported that thiamine was an effective crosslink inhibitor.45 They were at that time consuming two grams of thiamine each day in their personal antiaging regimens. Thiamine may ultimately also prove to be an effective crosslinkage breaker as well as inhibitor. Another thiamine derivative is the fat-soluble Benfotiamine. Benfotiamine is very helpful in the treatment of diabetic neuropathy at a dose of 300 mg twice daily. Carnosine: Dr. Alan Hipkiss of the Division of Biomolecular Sciences, King’s College London, reviewed the antiaging effects of carnosine and aminoguanidine.46 Dr. Hipkiss believes that one of the major mechanisms of the antiaging effects of carnosine is its powerful effects as a crosslink inhibitor and breaker, and that the use of these substances might help to control age-related molecular dysfunction. Carnosine has been used in doses generally ranging from 500-2,000 mg/day. Sorry for this long answer to your short question— but I believe that Dr. Bjorksten’s often overlooked contributions to the glycation/crosslinking theory need to be remembered and reemphasized. Ward Dean, M.D. References: For a complete list of references please 22

visit: www.antiaging-systems.com/content/27-askdr-ward-dean 1. Bjorksten, Johan. Recent developments in protein chemistry, Chem Industries, 1941,48: 746-751. 2. Bjorksten, Johan, and Champion, William J. Mechanical influence upon tanning, J American Chemical Society, 1942, 64: 868-869. 3. Bjorksten, Johan. A common molecular basis for the aging syndrome. J American Geriatrics Society, 1958, 6: 740-747. 4. Bjorksten, Johan, and Andrews, Fred. Fundamentals of aging: A comparison of the mortality curve for humans with a viscosity curve of gelatin during the cross-linking reaction. J American Geriatrics Society, 1960, 8: 632-637. 5. Bjorksten, Johan. Pathways to the decisive extension of the human specific lifespan, J American Geriatrics Soc., 1977 a, 25: 396-399. 6. Chappell, L.T., Stahl, J.P., and Evans, R. EDTA Chelation treatment for vascular disease: A Meta-Analysis using unpublished data. J Adv. Med, 1994, 7: 3, 131-142. 7. Lau, B. Garlic for Health, 1988, Lotus Light Publications, P.O. Box 2, Wilmot, Wisconsin 53192, pp. 31-32. 8. Wilkinson, S. Mercury removal by immobilized algae in batch culture systems, J Applied Phycology, 1990, 2: 223-230. 9. Yaeger, Luther L., and Bjorksten, Johan. Displacement of protein bound aluminum. Rejuvenation, 1984, 12: 12-14. 10. Tyler, A. Longevity of gametes: Histocompatibility, gene loss and neoplasia, in: Aging and Levels of Biochemical Organization, by Bruder, A.M., and Sacher, G.A. (eds), Section II, Part 11, 1965, U Chicago Press, Chicago, 50-86. 11. Tyler, A. Prolongation of life-span of sea urchin spermatozoa and improvement of the fertilization-reaction by treatment of spermatozoa and eggs with metal-chelating agents (amino acids, versene, DEDTC, Oxine, Cupron). Biol Bull, 1953, 104: 224. 12. Sincock, A.M. Calcium and aging in the rotifer Mytilina brevispina var redunca. J Gerontology, 1974, 29, 514-517. 13. Sincock, A.M. Life extension in the rotifer Mytilina brevispina var redunca by the application of chelating agents. J Gerontol, 1975, 30: 289. 14. Neigauz, B.M., and Ravin, V.K. Effect of physiologically active substances on the longevity of the nematode Caenorhabditis elegans. Zh. Obshch Biol, 1983, 44: 6, 835-841. 15. Komarov, L.V., and Bakaev, V.V. Means of the Life Prolongation, Rejuvenation, 1983, XI: 2-3, 46-51. 16. Spira, L. Clinical Aspects of Chronic Poisoning by Aluminum and its Alloys, 1933, Bale and Sons, London. 17. Galle, P. , and Duckett, S. X-ray microanalysis of pallidal arteries in Parkinson Disease, Sixth European Congress on Electron Microscopy, 1976, Jerusalem, 210-211. 18. Crapper, D.R., Kalrik, S., and DeBoni, U. Aluminum and other metals in senile (Alzheimer) dementia, in: Alzheimer’s Disease: Senile Dementia and Related Disorders, by Katzman, R., Terry, R.D., and Bick, K.L. (eds), 1978, Raven Press, New York. 19. Crapper DR, Krishnan SS, Quittkat S. Aluminium, neurofibrillary degeneration and Alzheimer’s disease. Brain. 1976 Mar; 99(1):67-80. 20. Zinsser, H., Bjorksten, I., Bruck, E.M., Baker, R.F., et al. The freezing pool: A unified sequence of the aging process, in: Medical and Clinical Aspects of Aging, by Blumenthal, H. T. (ed.), in: Proc 5th Int Assn Gerontology, 1962, Columbia U Press, 1962, 482-505. 21. Markesbery, W.R., Ehmann, W.D., Alauddin, M., and Nossain, T.I.M. Brain element concentrations in aging. Neurobiology of Aging, 1984,5: 19-28. 22. Bjorksten, Johan, Yaeger, Luther L., and Wallace, Terri. Control of aluminum ingestion and its relation to longevity. Internat J Vit Nutr Res, 1988, 58: 462-465. 23. Schenk, Roy U., Bjorksten, Johan, Lipert, Robert, and Mortell, Molly. Extraction of aluminum from aorta tissues by chelating agents and lactic acid. Rejuvenation, 1981, 9: 4-10. 24. Dean, W. DMAE and PABA — An alternative to Gerovital (GH3), the ‘Romanian Youth Drug,’ Vitamin Research News, 2001, 15: 9, 1-7. 25. Zs.-Nagy, I., and Nagy, K. On the role of cross-linking of cellular proteins in aging. Mech Aging Dev, 14: 245-251, 1980. 26. Yaeger, Luther L. Electrolytic scission of hexadentate aluminum bonds. Rejuvenation, 1983, 11: 76-80. 27. Yaeger, Luther L., and Bjorksten, Johan. Displacement of protein bound aluminum. Rejuvenation, 1984, 12: 12-14. 28. Fugate, L. Potential Role for Lithium in Preventing Alzheimer’s disease. Vitamin Research News, 2002, 16: 2, 1-7. 29. Monnier, V.M., Kohn, R.P., Cerami, A. Proc. Natl. Acad. Sci., 1984, 81: 583-587. 30. Dyer, D.G., Blackledge, J.A., Katz, B.M., Hull, C.J., Adkisson, H.D., Thorpe, S.R., Lyons, T.J., and Baynes, J.W. The Maillard reaction in vivo. Z. Emahrungswiss-enschaft, 1991, 30: 29-45. 31. Khalifah, R.G., Baynes, J.W., and Hudson, B.G. Amadorins: Novel post-Amadori inhibitors of Advanced Glycation Reactions. Biochem. and Biophys. Res Comm., 1999, 257, 251-258. 32. Brownlee, M., Cerami, A., Vlassara, H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N. Engl. J Med, 1988, 318: 1315-1321. 33. Cohen, M., and Van, Y. Age-related changes in non-enzymatic glycosylation of human basement membranes, Exp. Gerontol., 1983 , 18: 6, 461-468. 34. Vlassara, H. Advanced glycation end-products and atherosclerosis. Annals of Medicine, 1996, 28: 419-426. 35. Van Boekel, The role of glycation in aging and diabetes mellitus. Molecular Biology Reports, 1991, 15: 57-64. 36. Dean, W. Aging Matters, 37. Brownlee, M. Non-enzymatic glycosylation of macromolecules—Prospects of pharmacologic modulation, Diabetes, 1992, 41: Suppl. 2, 57-60. 38. Friedman, E.A. Advanced glycosylated end products and hyperglycemia in the pathogenesis of diabetic complications. Diabetes Care, 1999, 22: Supplement 2, B65-B71. 39. Mruthint, S., Green, K., and Abraham, E. Inhibition of cataracts in moderately diabetic rats by aminoguanidine. Exp. Eye Res, 1996, 62: 505-510. 40. Forbes, J., Soulis, T., Thallas, V., Panagiotopoulos, S., Long, D., Vasan, et al. Reno-protective effects of a novel inhibitor of advanced glycation. Diabetalogia, 2001, 44: 1, 108-114. 41. Brownlee, M. Glycation products and the pathogenesis of diabetic complications, Diabetes Care, 1992, 15: 12, 1835-1843. 42. Makita, Z., Vlassara, H., Rayfield, E., et al. Hemoglobin-AGE. A circulating marker of advanced glycosylation Science, 1992, 258: 651-653. 43. Sell, D.R., Monnier, V.M. [pentosidine] J Biol. Chem., 1989, 264: 21597-21602. 44. Khatami, M., Suldan, Z., David, I., Li, W., and Rockey, H. Inhibitory effects of pyridoxal phosphate, ascorbate and aminoguanidine on non-enzymatic glycosylation, Life Sciences, 43: 1725-1731. 45. Pearson, D., and Shaw, S. Life Extension—A Practical, Scientific Approach. Warner Books, New York, 1983. 46. Hipkiss, A., Brownson, C. A possible new role for the antiaging peptide. , 2000, 57(5): 747-53. 47. Dean, W. Carnosine: Multipurpose Anti-Aging Nutrient. Vitamin Research News, 2004, 18(9), 1-12.

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damaging effects such as glycosylation and mitochondrial decline.

Featured products

UPDATE: ACF228 is now also available in a specially designed mouth inhaler. The ACF228 Breathe-Easy can help those worried about their lung capacity and function, to help protect against oxygen deprivation and hopefully avoid the need for long term use of corticosteroids. In addition to the original ACF228 formula it also contains glutathione. For further details about ACF228 and much more besides we recommend Dr. Lippman’s latest book ‘Stay 40.’

1st Line™ (thiocyanate) 1st Line is an exciting new and all natural weapon in the fight against various types of infections including viruses. 1st Line contains a patented formula that when made up with water becomes a drink that contains thiocyanate ions.

Adrafinil (Olmifon®)

Thiocyanate ions (also known as oxythiocynate) are the same molecules made in body’s airways and passages, for example they can be found in tears, saliva and milk and they literally form the body’s first line of defence against all types of bacteria, yeasts, fungi, flukes, germs and even viruses, helping to destroy them on contact. Consuming 1st Line helps to flood the bloodstream with thiocyanates, but unlike antibiotics 1st Line does not attack self-molecules, in other words beneficial floras are not disturbed. Clinical trials have exposed that 1st Line can help quickly to combat various infections relating to helicobacter, pneumonia, soft tissue infections, upper respiratory tract infections and bronchial infections. Other doctors have reported to us that their patients with various viral infections are asymptomatic, even months later after using a few doses of 1st Line. “...thiocyanate ions are not toxic to human cells... and have little if any effect on probiotic species, making them a near perfect antibiotic system.” Professor Paul Clayton

ACF228™ Dr. Lippman was nominated for the Nobel Prize in Medicine for his work to measure free radical production within the body and as everyone knows free radicals are unstable molecules that cause a lot of damage associated with aging and degeneration. The result of Dr. Lippman’s work is the unique patented and exclusive to IAS- ACF228 (this stands for ‘antiaging complete formula’ version 228). The capsules are designed to neutralise damaging free radical production and help to reduce other age related

Adrafinil works like modafinil- it resensitizes alpha-1 receptors in the brain to be more sensitive to noradrenaline. This heightens awareness and concentration to prevent narcolepsy (sleeping in the daytime). The results can be quite remarkable, leading to heightened states of awareness and attention, whilst at the same time not affecting sleep patterns nor causing ‘highs and lows’ that were associated with the earlier form of stimulants. Adrafinil is not recommended for continuous use past 3-months unless liver enzymes are being monitored.

Aminoguanidine (pimagedine) Aminoguanidine is internationally recognised as the most potent AGE inhibitor currently available. The abbreviation AGE means ‘advanced glycated end products.’ AGEs are cross linked proteins that do not work efficiently/ correctly and are seen in a number of disorders including diabetes, heart enlargement, skin discoloration and hardening (particularly in smokers), cataracts and even arterial stiffness. (If you want to see glycosylation in action, then cut an apple in half and watch it turn yellow and tough). Our aminoguanidine tablets also contain vitamin B6 so there is no need for extra supplementation.

Andro-Pro™ Andro-Pro contains the latest cutting-edge nutritional ingredients to naturally boost free testosterone levels. The most unique ingredient added to Andro-Pro is the recently discovered fructoborate. Fructoborate is a boron derivative that according to Romanian

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studies is helping to alleviate bone loss and arthritis; but perhaps the most interesting clinical study was done on 13 men. They were given the equivalent of one capsule of AndroPro daily for 60-days, at the end of the 2 months, on average these men experienced serum level increases of vitamin D by 19.6%, DHEA-S up 56% and free testosterone rose by 29.5%. In addition, Andro-Pro also contains the supporting agents of zinc, B6, magnesium and high quality tribulus terrestris. All factors in improving free testosterone production. Adding DIM-Pro 2™ to your regime can help to reduce estrogen levels and therefore improve free testosterone levels even further.

ATP Boost™ ATP-Boost provides 20mg of ATP, the body’s ultimate energy molecule in each capsule. In addition, ATP Boost contains a unique combination of the nutrients acetylL-carnitine and R-lipoic acid that increase mitochondria energy production without the increase in damaging oxidation that usually follows. The result: enhanced energy reserves and reduced aging at the cellular level.

BEC5 Curaderm® BEC5 Curaderm cream was discovered by Dr. Bill Cham on the Oceania island of Vanuatu. Dr. Cham noticed that when the local farmers rubbed the plant called the ‘devil’s apple’ (found in that region and which is related to eggplant) onto the backs on animals that were experiencing skin cancers- that they had considerable success in its removal. It is known that BEC5 Curaderm has now been used by more than 80,000 patients, all with remarkable success. Clinical trials in the UK and Australia have confirmed the ability of BEC

The eggplant cancer cure by Bill Cham Ph.D. covers all aspects of BEC5 Curaderm treatment. Curaderm to regress non-melanoma skin cancers within weeks! For example, one open study with 72 patients had 100% healed skin cancer lesions within just 13-weeks of applying BEC5 Curaderm cream twice daily. “BEC5 Curaderm is a topical preparation which is safe and effective, an ideal therapy for outpatient treatment... It is a cost effective treatment for both primary and secondary skin cancer care.” Dermatologists at the Royal London Hospital 24

Here are examples of patients before, during and after treatment with BEC5 Curaderm. A typical treatment period from start to finish is 8 weeks. Furthermore, BEC5 Curaderm is known not to harm healthy cells, therefore only destroying cancer cells on and under the skin’s surface. “What’s near perfection? BEC5 Curadermit’s a treatment that works nearly every time. It’s incredibly simple to use, has no adverse side effects and is inexpensive compared with other treatments.” Jonathan Wright, M.D. BEC5 Curaderm is known to be effective for all the following conditions:

• • • • • •

Basal cell carcinomas (BCC) Squamous cell carcinomas (SCC) Keratoses Keratoacanthomas Age spots Sun spots

UPDATE: To achieve the best possible results in the quickest possible time, use HemaGel® and tamanu oil following the BEC5 treatment.

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The most commonly expressed initial reports are that glare is significantly improved, (for example night driving is much safer) and color perception is enhanced.

BCI program Dr Garry Gordon is a world expert in detox and chelation (the removal of heavy metals). His oral BCI program is a world leader. Made up of 3 products, it not only provides the right natural materials to help lock-up, remove from tissues, transport through the body and excrete toxins, but also a plethora of protective vitamins, minerals and oils that have been designed to make it as easy as possible to have the most comprehensive all-in-one package.

What’s more evidence is mounting that Can-C is efficacious for all of the following disorders: cataracts, glaucoma, presbyopia, corneal disorders, eye strain, ocular inflammation, blurred vision, dry eye syndrome, vitreous opacities and lesions, diabeteS mellitus complications, contact lens wearers, (regarding the last point in the list above, Can-C inhibits the accumulation of lactic acid which has greatly benefited those who wear contact lenses, because it enables them to be worn for longer without pain).

Each sachet in the Beyond Chelation Improved® contains 3 vitamin/ mineral pills, 3 chelation/ detox capsules, 1 omega 3 fish oil capsule, 1 omega 6 & 9 evening primrose capsule and 1 brain capsule containing gingko biloba and phosphatidylserine. This is a superb daily nutritional supplement just by itself, but to avail yourself of the full program you should add two more agents; these are: Bio-En’R-Gy C® a unique high-strength and stabilised vitamin C powder that can be added to water or juice. It also contains ribose for your heart health along with MSM, betaine and bioperine to lower inflammation and problematic lipids. Fundamentally, it is this product that transports the toxins from the tissues sites that Beyond Chelation Improved® has released, ready for them to be excreted. Then it is over to Dr Gordon’s Beyond Fiber®. It contains the best forms of fiber, specifically extracted from brown rice husks and Jerusalem artichoke, in addition with EDTA. This product enables the body to defecate the toxins collected into the gut from the body. Simply add a scoop of the powder into your morning cereals or blend it into your power drink. Finally, for those who want to get metals out of their skin, use Beyond Clean® version 2. This powder is simply added to the bath tub and contains both EDTA and zeolite. Here you simply relax your toxins away!

Can-C™ eye-drops Can-C eye-drops are the original formula for use in cataract and contains a purified and racemized form of n-acetylcarnosine, a natural di-peptide with potent antiglycating and anti-oxidant properties that prevent lipid peroxidation.

Left: A woman’s eye shows the cataract before treatment. Right: 5-months later after use of Can-C eye-drops (two drops twice daily), there is no longer a visible cataract and eyesight has improved. Dr. Kyriazis book, ‘the cataract cure’, details the usefulness and evidence of Can-C eye-drops. Now available from IAS as a FREE e-book: http://www.antiaging-systems.com/can-c-ebook “I am so grateful for the development of Can-C eye-drops, not only have they significantly improved my own eyesight, but many of my patients report most favorably about them too. Now we have a real alternative to eye surgery so Can-C can be considered to be a genuine breakthrough.” Richard Lippman, Ph.D.

Can-C Plus™

Patients in trials placed 2-drops of Can-C into their eyes twice daily. After 6-months of use, 88.9% of patients showed improvement in the clarity of their lens and 90% saw an improvement in their visual acuity. There have been numerous reports of cataract shrinkage and even disappearance with documented evidence that Can-C eyedrops remain effective (and safe) more than 24-months later.

Can-C Plus capsules are specially designed to be used alongside the Can-C™ eye-drops to aid and even boost their effectiveness. As there are a few supplements that can block the action of Can-C eye-drops, Can-C Plus capsules have been carefully designed to avoid them. Three Can-C Plus capsules a day can be taken with food, with or without Can-C eye-drops, although for maximum benefit it is recommended that they are used together.

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Centrophenoxine (Cent-Pro™) Like all good antiaging supplements, centrophenoxine has many useful features with few side effects. From a memory and cognition viewpoint, centrophenoxine has demonstrated significant improvements, most notably its ability to speed up the process of memory recall. One of centrophenoxine’s most noted benefit’s is its ability to effectively and quickly remove a cell toxin that accumulates with age (and Alzheimer’s disease) called lipofuscin. Lipofuscin can make up parts of the socalled Alzheimer brain plaques, but it can even be found in the brains of ‘normal’ aging people as well as other organs such as the heart, the lungs and even the skin- where it forms part of the so-called age or liver-spots, the brown flecks found in ‘aged’ person’s skin. Indeed several weeks of centrophenoxine supplementation has seen removal and lightening of such spots. “Centrophenoxine has shown many facets to improve conditions related to my membrane hypothesis of aging, for example its ability to improve brain-performance, survival time in animal experiments, and to remove the cell aging-pigment called lipofuscin. It has been my antiaging supplement for more than 30-years.” Professor Imre Zs.-Nagy

CoQ10 (coenzyme Q10) CoQ10 is a universal energy agent that has significant protective qualities for the heart and the cardiovascular system. An important point- anyone taking a statin drug to lower cholesterol must also be taking CoQ10 since statins lower CoQ10 levels.

UPDATE: Our CoQ10SR™ is a slow release version

combined with cyclodextrin, a new technology that enables greater bioavailability by improving the passage through the stomach into the blood. It has been clinically shown that CoQ10SR™ has up to twice the bioavailability of ‘regular’ CoQ10. Thus depending on how you look at it, CoQ10SR is either double the effectiveness of CoQ10’s of the same dose, or half the price of CoQ10’s of twice the dose!

Crème-Pro™ Cellulite The specialist range of Crème-Pro creams work to attack and defend against all aspects of aging skin problems; here the cellulite contains a high 10% of phosphatidylcholine, proven to help reduce the appearance of cellulite. Simply apply regularly onto clean, dry skin on the inner thighs and buttocks or wherever cellulite appears. (Avoid the eyes). 26

Crème-Pro™ Moisturizer Crème-Pro™ Moisturizer is a unique combination of hyaluronic acid, procaine, NADH and vitamin B12 helps to keep skin looking plump, moist and radiant. Simply apply it onto clean dry skin once or twice daily. (Avoid the eyes).

Crème-Pro™ Protector Crème-Pro Protector is a day cream designed to help protect the skin against environmental agents, including sunlight and oxygen as well as pollution. The agents can attack skin and make it age prematurely through their oxidative effects. The most unique agent in the Protector cream is idebenone. Idebenone is the single most potent antioxidant yet studied, and rarely found except in the most expensive antiaging skin creams. Apply onto clean dry skin and use it as a regular day cream. (Avoid the eyes).

Crème-Pro™ Smoother Crème-Pro Smoother is designed to be the alternative to injectable nerve freezing agents such as Botox®. Smoother can be applied to any fine lines such as crows’ feet around the eyes and around the lips etc. It contains synthetic snake venom that temporarily paralyses nerves in the skin, thereby relaxing and unfolding the skin in that region, immediately reducing the wrinkles and producing younger looking skin. (Avoid the eyes).

Curcumin™ By harnessing the power of the natural healer, curcumin, (found in turmeric) we have access to a wide-ranging set of positives. From bolstering the immune system, it also acts as an anti-viral and an anti-fungal agent, to moderating inflammatory response; curcumin’s a true generalist. It’s even been found to have the ability to counter many conditions including a very recent study as an anti-depressive.

UPDATE: Our CurcuminSR™ is a unique slow release version that is much more bioavailable than regular versions.

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Esnatri™ cream (bio-identical estrogens)

Deprenyl (selegiline) Parkinson’s disease is characterised by the loss of the brain neurotransmitter dopamine. Deprenyl helps to prevent this loss by acting on the specific enzyme MAO-b. Professor Knoll also believes that deprenyl very significantly increases PEA (phenylethylamine) and that this may have an even more significant function than the MAO-b inhibition, (for more details on this please read Professor Knoll’s excellent book on the subject- ‘the brain and its self’). Professor Jozeph Knoll of Debrechen University in Hungary- the inventor of deprenyl

In addition to improving dopamine levels, deprenyl has also been shown to help rebalance serotonin, noradrenaline and acetylcholine levels and whilst the uses remain ‘off-label’ deprenyl has been used for Alzheimer’s and even cancer treatments. Our focus here is upon deprenyl’s enhancement of dopamine, which is a key brain chemical responsible for drive, focus and well being and even libido (especially for men). The experiments of Professor Jozeph Knoll dramatically extended the lifespan of rats who were given deprenyl. Even the first rat to die that was treated with deprenyl died after the last rat not treated with deprenyl died.

Esnatri cream is the world’s only bioidentical estrogen cream to replicate the work of Dr. Jonathan Wright. Dr. Wright has highlighted that the ‘average’ woman produces estrogens in the ratios of estriol 90%, estradiol 7% and estrone 3% and these are the exact same ratios found inside Esnatri. Each 1ml of Esnatri cream provides 2mg in total of the triple estrogens and it enables a precise, natural and indeed bioidentical hormone replacement therapy for women concerned about the menopause. IAS provides dose and timing advice from Dr. Wright for both estrogens and progesterone with every purchase. The additional use of bioidentical progesterone should be used along with an estrogen replacement program. For further information on estrogens we recommend one of Dr. Thierry Hertoghe’s Hormone handbooks.

GABOB (Gamibetal®) (technically it is the closest legal molecule to GHB). Its approved use in Europe is to help with epilepsy, but like GHB, GABOB has been shown to improve growth hormone release significantly when taken before bedtime. GABOB does not have the ‘sleep inducing’ effects of GHB, but it can cause some sedation if taken in high doses.

GHRP2 GHRP2 is growth hormone releasing peptide number 2. It is a potent releaser of HGH for fat loss and is particularly synergistic with sermorelin. It is best taken in the morning, by swallowing 4ml of the liquid.

This graph highlights the loss of dopamine with age, on average 13% per decade past the age of 40 for the average person, but far greater for those suffering from Parkinson’s disease

UPDATE: GHRP2 is synergistic with sermorelin.

Glutathione (also see ACF228™ Breathe-Easy)

The idea behind the antiaging use of deprenyl is to use very small doses regularly in order to help maintain healthy dopamine levels and thus improve cognitive function and help to maintain function at a better level for much longer.

UPDATE: The Dep-Pro™ liquid can dispense selegiline HCL in small quantities as 1 drop = 1 mg.

Glutathione is a potent antioxidant that helps to prevent damage to important cellular components that can be caused by reactive oxygen species such as free radicals and peroxides. Glutathione is principally synthesized inside the body and is relatively poorly obtained via the diet. The Advanced Cellular Glutathione supplement is a spray providing nano sized particles for sub mucosal absorption to create instant bioavailability.

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Hair-Pro™ Hair-Pro is the very latest development to help induce hair growth. It contains the absolute latest cutting-edge growth factor technologies. Hair Pro is a unique proprietary topical liquid blend that includes finasteride, (the DHT blocking drug used orally for years as a hair loss treatment). It also contains a plethora of amino acids that act as hair growth factors including bFGF, TRX, VEGF and IGF-1. In addition there is aminosyn to promote protein synthesis (hair strength), hyaluronic acid to aid hair hydration (thickness) and dexpanthenol to cleanse the pores of the blocking fat- sebum which can block nutrition from the hair root. It’s a unique and potent formula to battle alopecia. UPDATE: Use it in combination with the Scalproller to improve uptake into the scalp.

HemaGel® HemaGel was created in the Czech Republic and specially designed to help improve the treatment times of wounds, scratches and cuts, reducing the start-to-finish treatment time by as much as 50%. It does this (1) by absorbing harmful and damaging free radicals and (2) by helping to absorb blood and puss extrudes, thus also keeping the wound cleaner. HemaGel is recommend for use after BEC5 Curaderm applications to speed up the skin’s healing. It is also as an excellent product to have in the First Aid cabinet- just in case! Simply apply the HemaGel daily onto a cleaned (and disinfected) wound, and then apply a bandage over it.

Hydergine (ergoloid mesylate) Hydergine is an extract of a fungus that grows on rye called ergoloid mesylate. Its approved uses have been to aid persons with memory disturbances, Alzheimer’s disease and even for persons who have suffered from electric shock, drowning or suffocation. This is because hydergine stabilises the levels of oxygen in the brain. It has been shown to improve oxygen levels when they are too low and even decrease levels when they are too high. The result of this optimised oxygen availability in the brain is an ability to do more mental work without becoming tired. Accordingly, hydergine can be a good tool to battle through boring paperwork or a long drive home in the dark. A fascinating animal experiment showed a special ability for hydergine to improve mitochondrial condition. The mitochondria are vital organelles found in every cell of our body responsible for the generation of ATP, the universal energy molecule. Unfortunately mitochondrial efficiency declines as we age. However, an Italian study highlighted that old animal mitochondria can be improved with hydergine supplementation. 28

The Bertonin-Freddari et al, 1994 study highlights that hydergine can improve the size, volume and number of mitochondria in old animals- towards the youthful example; as is shown here the difference between young, old (without hydergine) and old (with hydergine) is significant. Hydergine also stimulates the growth of dendrite nerve fibers. These connective strands are known to decline in aging. This is another antiaging feature of hydergine. Some have even linked the density and numbers of dendrite fibers to the level of I.Q. In summary, hydergine helps to protect against conditions of hypoxia and peroxidation, important factors to guard against a stroke and generalised brain injuries. Hydergine can extend the boundaries of mental workload and energy, fighting against boredom and may even provide some groundwork for raising the levels of intelligence. The liquid form can be titrated in small doses and may be more suitable for those who want low doses or have trouble swallowing tablets.

Melatonin (MZS™) Melatonin is one of nature’s remarkable substances. It is made in response to darkness by the pineal gland. Melatonin’s benefits to help overcome jet lag and shift work have become quite well known and indeed it is useful for this purpose since adequate melatonin availability enables our bodies to be correctly in tune with our circadian rhythms. These circadian rhythms dictate our hormonal cyclicity and this cyclicity ultimately determine our aging and our level of immunity. Unfortunately melatonin secretions decline with aging. Professor Pierpaoli has published widely on melatonin, principally through the New York Academy of Science and at the meetings of the Stromboli conferences on aging and cancer- which IAS is delighted to support. What is important to know about melatonin is that Professor Pierpaoli advocates a 3mg dose to (his words) “put the pineal to sleep.” In addition, it is also vital to use a melatonin that produces a night peak of melatonin that is the same as the peak produced by the pineal itself. This he has achieved using specific excipients in his own formula ‘MZS™’ (which also contains the additional synergistic ingredients of zinc and selenium). This graph highlights that Professor Pierpaoli’s Melatonin Zn Se formula mimics the night peak of melatonin. Note that sublingual melatonin tested peaks too soon and that time released formulas peak too late.

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Here are some before and after Fundus photos showing the benefit of Melatonin Zn Se. They highlight dramatic improvements to both wet and dry forms of macular degeneration. In a trial published in the New York Academy of Science, 110 eyes, (100 patients) with both wet and dry forms of ARMD were treated only with 1 tablet of Melatonin Zn Se nightly. After 6-months 90% of the treated patients’ eyes had significant improvements to their condition. This is simply remarkable compared to the current approved therapy for ARMD which involves injecting the eye quarterly, (costs $1000+) with 50% improvement at 24-months! For further detailed information about melatonin and Professor Pierpaoli’s work we recommend his book ‘the key of life,’ it is now available as a FREE e-book from the IAS website.

MSH2-Pro™ MSH2 is the abbreviation for melanocyte stimulating hormone (type II). This hormone has a direct effect on tanning the skin and if used regularly will darken skin- even without exposure to the sun. In addition, MSH has been noted to enhance libido and suppress the desire to eat. NOTE: MSH use should not exceed 2-sprays per day and must not be used by persons with hypertension, (high blood pressure).

Naltrexone The results of low dose naltrexone, (widely known as LDN) therapy have been remarkable. Originally, the use of naltrexone was in the management of dependence on opioid and alcohol. But it was Dr. Bernard Bihari in the 1980’s who first used low dose naltrexone for the treatment of HIV and then for a number of other autoimmune diseases such as multiple sclerosis, Crohn’s disease and many immunological related diseases. Many MS patients have reported an improved quality of life. A leading study has established that by maintaining regular nightly LDN, less than 1% of the MS sufferers experience fresh MS attacks. IAS supplies the LDN dose of 4.5 mg.

Oxytocin (Oxy-Pro™) Oxytocin is a hormone produced in the hypothalamus and secreted into the blood by the pituitary gland. Oxytocin has been described in detail in Dr. Thierry Hertoghe’s latest book- Passion, Sex and Adventure, the oxytocin story. Oxytocin has pain curbing abilities and could be efficacious in fibromyalgia. Other studies are highlighting that oxytocin could be efficacious in the treatment of autism and even schizophrenias. But it is perhaps its ability to enhance bonding between partners that is likely to attract most attention. Oxytocin increases ejaculate in the male and has significant libido enhancement effects in females, including the inducement of multiple orgasms. We have worked alongside Dr. Hertoghe to create a practical and efficacious sublingual trouche (a gel like tablet). Typical doses are 5 to 20 IU. (The square troches can be cut in half from corner to corner easily).

UPDATE: Oxy-Pro™ is a new nasal spray version of oxytocin (delivering 10 IU per spray) in addition to our 20 IU sublingual trouches.

Peptide Bioregulators These are the very latest technology from Professor Khavinson in Russia. They utilise highly specific peptides extracted from Danish bovine sources. These peptides have been shown to be a short-cut to protein synthesis by activating directly with their receptive genes. Therefore their action is to ‘reinvigorate’ their respective gland/ organ, to induce their biological reserve and essentially rejuvenate their processes. 1.Bonomarlot® is the peptide for the bone marrow. 2.Bobothyrk® is the peptide for the parathyroid. 3.Cerluten® is the peptide for the central nervous system (brain). 4.Chelohart® is the peptide for the heart. 5.Chitomur® is the peptide for the bladder. 6.Endoluten® is the peptide for the pineal. 7.Glandokort® is the peptide for the adrenal glands. 8.Gotratix® is the peptide for the muscles. 9.Libidon® is the peptide for the prostate gland. 10.Pielotak® is the peptide for the kidneys. 11.Sigumir® is the peptide for the cartilage. 12.Suprefort® is the peptide for the pancreas. 13.Stamakort® is the peptide for the stomach. 14.Svetinorm® is the peptide for the liver. 15.Taxorest® is the peptide for the lungs. 16.Testoluten® is the peptide for the testes.

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17.Thyreogen® is the peptide for the thyroid. 18.Ventfort® is the peptide for the blood vessels. 19.Vladonix® is the peptide for the thymus. 20.Visoluten® is the peptide for the eye retina. 21.Zhenoluten® is the peptide for the ovaries.

The recommended course is 2 capsules each day for 10-days (total 20-capsules). For general health support this can be repeated again in 6-months’ time. Thus only 2 boxes are required for a year! For those in greater need the 10-day course can be repeated monthly, bi-monthly or quarterly as needed.

UPDATE: An intensive course is 1 or 2 capsules twice a day for 30-days.

Piracetam (Nootropil®; also see Anacervix®) Piracetam was the very first nootropic, (commonly called smart drugs) to be developed. Despite being one of the very first products that IAS offered when we went online in 1991, it remains one of our best selling products today! Why? Because it is a very beneficial memory agent that has a great safety record, with very few side effects. Plus, it is cost effective. Piracetam has been shown to be safer than salt. This may be because it has a very small impact upon brain chemical levels and helps to improve electrical communication across the brain’s corpus callosum. The corpus callosum is the bundle of nerves that separates the two hemispheres of the brain. In medical terms piracetam is used to improve short term memory and to treat a wide variety of senile dementias as well as autism and Down’s syndrome and can also assist with travel and altitude sickness. Note: IAS offers the original UCB brand called Nootropil which is available in tablet and liquid form. The liquid form was specifically designed for children (it is sweetened with saccharin), but its advantages include being able to titrate low doses (if required) and also aid any person who has difficulty swallowing tablets.

NEW: A great value generic piracetam is now available under the name of Pira-Pro™.

Progesterone Progesterone is often the ‘missing’ hormone in the treatment of female menopause. What we mean by this is that whilst estrogen treatments, (see Esnatri™ for details) are often considered as a primary replacement hormone for women, progesterone is often forgotten about. The best known action of progesterone is its ability to help build bone mass. Progesterone levels fall rapidly in menopause and contribute to osteoporosis. Progesterone is strongly advocated to be taken in combination with any estrogen replacement program. 30

UPDATE: Our progesterone strength is Pharma grade. It is twice the dose that is found in US health food stores. Progesterone levels decline in women with age; in some cases progesterone levels are undetectable! We recommend one of Dr. Hertoghe’s hormone handbooks for further information about progesterone.

PQQ (pyroloquinoline quinone) PQQ is the most newly discovered vitamin. In more than 200 studies it has been shown to improve overall energy levels, cognitive function and memory, reduce mitochondrial degradation and increase skin elasticity. Furthermore, it acts as a neuro and cardio protectant and helps to enhance nerve growth.

Releasing-Pro® Releasing-Pro is a unique nasal spray that is designed to carry GHRP-6 into the bloodstream. GHRP-6 is an analogue of Ghrelin that has been shown to have significant enhancement effects on IGF-1 levels.

Retin-A®

(Retirides®)

Retin-A contains retinolic acid, a pure form of vitamin A that enhances blood supply to the skin’s surface and transforms the thicker, tougher skin into more youthful looking, elastic and fresher skin. Retin-A is the cream of choice for cosmetic surgeons to speed up the wound healing of cosmetic surgery and scarring etc.

UPDATE: We now also supply the new Retin-A® micro-gel which is designed to sit on the skin surface and release slowly.

Sermorelin

(Serm-Pro™)

Sermorelin is a breakthrough development in the field of growth hormone (GH) replacement. Sermorelin is the bioidentical molecule used by the pituitary gland to stimulate the production and release of GH into the bloodstream. Sermorelin is not GH; GH is a complicated molecule consisting of 191 amino acids. Sermorelin is a chain of 29 amino acids. Importantly

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it is the first 29 amino acids of GH, the part responsible for activation. This is what makes sermorelin stand head and shoulders over all previous agonists of GH. Sermorelin is GH site-specific and therefore very effective. What is more, sermorelin has a negative feedback loop (unlike GH itself), so the issues of overdosing and safety associated with injections of GH are minimized/ completely avoided. Sermorelin is stable at room temperature and efficacious when used sublingually. These are additional factors that favor sermorelin as the next generation of GH activators. We are excited to introduce this sublingual liquid version of sermorelin which has been created with the close cooperation of Dr. Richard Walker of SARA (Scientific Applied Research into Aging), a world renowned antiaging expert.

population could be hypothyroid. Thyroid supplements come in two forms; natural supplements and synthetic supplements. It is almost always better to use a whole-natural thyroid extract because the synthetic versions usually only comprise one of the thyroid hormones, (such as, T3 or T4), whereas, wholenatural thyroids cover a fuller spectrum of thyroid hormones (including T1, T2, T3 and T4). For further details about thyroid we recommended one of Dr. Hertoghe’s hormone handbooks.

UPDATE: Sermorelin is synergistic with GHRP2 or GHRP6.

TRH is a hypothalamic hormone (technically a tri-peptide) whose real uses and benefits are just coming to the fore, primarily after research conducted by Dr. Walter Pierpaoli, the physician and scientist who exposed the benefits of melatonin to the world. Dr. Pierpaoli’s research suggests that TRH is a ‘master’ hormone responsible not just for helping to adjust thyroid hormones (its principle recognised role), but in helping to recorrect many imbalances throughout the body. For example in his animal experiments TRH supplements have encouraged old animals to:

TA65® TA65 contains a highly purified specialized extract of the Chinese herb astragalus. What makes this supplement totally unique is that it is the first natural substance that has been proven to act as a telomerase activator and to extend telomeres in humans (in-vivo). Telomeres are the strands on the ends of chromosomes that shorter each time the cell divides. This is a significant part of the destructive process of aging. Animals with longer telomeres enjoy a more productive and healthier older age and appear to live longer. TA65 production is carefully controlled by TA Sciences, who purchased the technology from the Geron Corporation. Whilst other substances have claimed to delay the shortening of telomeres, only TA65 has been clinically proven (and published) to actually lengthen short telomeres in humans. If you want the cutting-edge of antiaging supplementation and the best possible chances for longer telomeres, then TA65 is currently your best (and indeed only) clinically proven choice.

Thyroid (Armour®; Synthroid®) A decline in the secretion of hormones from the thyroid gland (hypothyroidism) can result in poor concentration, confusion, memory problems, cold hands and feet, weight gain, menstrual problems, sleep disorders, dry skin, thinning hair and low energy levels. An underactive thyroid is also a major cause of a common painful musculoskeletal condition known as fibromyalgia. Aging often leads to hypothyroidism. One of the most famous thyroid experts, Dr. Broda Barnes, stated that as many as 40% of the adult

UPDATE: ERFA now available in value 500 tablet packs.

TRH (Abaris™)

•

Re-establish spermogenesis, (reversing the age-related dysfunction of their testes).

•

Correct kidney dysfunction, (a significant finding for renal issues).

•

Correct pancreatic dysfunction, (a significant finding for diabetic issues).

•

Improves many lipid profiles and aids weight loss when used over a few months.

IAS is delighted to be the first organisation in the world to offer a sublingual TRH tablet.

Vasopressin Vasopressin is a porcine extracted source for this pituitary hormone which has a number of interesting roles. Its approved medical use is to prevent frequent urination in conditions such as diabetes insipidus. For example, men with prostate conditions can benefit by less trips in the night to urinate. But vasopressin is also responsible for the laying down of memories in the hippocampus and it has been used to treat amnesia. In particular, it is cited by many for memory imprinting, this is the learning of new material before it is experienced. Therefore taking 1 or 2 sprays into each nostril 15-minutes before an exam, meeting or lecture etc., can induce a better detailed recall of events later.

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Product A-Z listing Here is an alphabetical listing of IAS stocked products. See our cross-reference list of disorders that relate to these individual products. Much more information is available from our website including full ingredient/ excipient listings, doses and side effects etc. If you need any further information or can’t find what you require, please don’t hesitate to contact us. The inside back cover has all our details.

Testimonials “IAS has shown great vision and leadership, as an organisation focused mainly on the provision of contemporary medical interventions against aging, and in also supporting the SENS Foundation’s efforts to hasten the development of much more powerful future interventions.” Dr. Aubrey De Grey “IAS is an outstanding resource for the finest, most up-to-date news and information on healthy aging. They also offer products of the highest integrity and efficacy. In fact, IAS is the world’s greatest source (often the only source) for the most cutting edge and advanced nutrients to ensure optimum health span and maximum life span.” Nicholas Perricone, M.D.

The following index underneath certain products means that known restrictions apply. For example: Not shipped to UK Not shipped to EU Not shipped to Japan Not shipped to Australia (or New Zealand) Note: For use strictly by IAS private club members - IAS terms and conditions apply. All information is educational and does not replace the advice of your physician. Prescriptions are necessary where required by law; other restrictions may apply in some countries.

“IAS has a history of making throughout the world crucial, but difficultly accessible medications available to patients. IAS is one of the pioneering societies in antiaging medicine that has helped this new medical specialty move forward.” Thierry Hertoghe, M.D. “I am a 77 year old Physician who has practiced medicine for nearly half a century. My antiaging research has permitted me to overcome serious health problems. Everyone can do this, but it requires specialized knowledge and the highest quality products. IAS is a vital link in my antiaging program because they continually provide both accurate information AND the high quality products we all require, if we are to achieve our maximum intended useful lifespan.” Garry Gordon, MD, DO, MD (H) “Every adult has the right to take care of his or her own personal health as he or she chooses. In the 20th and 21st centuries, this universal human right has been nearly obliterated by an ocean of nanny-state regulation and deliberate suppression of information by bureaucracies, with hidden and not-so-hidden agendas. International Antiaging Systems is a beacon of useful health care information and a literal island of freedom of health care product choice in our otherwise un-free health care world.” Jonathan Wright, M.D. See all professional and public testimonials at: www.antiaging-systems.com/content/11-testimonials

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1st Line™ (OSCN, thiocyanate)

Anacervix®

5HTP (5-hydroxy-tryptophan)

Anastrozole (Arimidex®)

1 complete kit retail $90 IAS price $79.99 Item Code: 675

5HTP-Pro™ 60x 50mg capsules retail $20 IAS price $17.99 - Item Code: 327

Acarbose

Glucobay® 30x 100mg tablets retail $29 IAS price $24.99 - Item Code: 373

Acetyl-L-Carnitine (see ATP-Boost™)

ACF228™

ACF228™ 45 capsules retail $60 IAS price $49.99 - Item Code: 621

NEW: ACF228™ Breathe-Easy 1 inhaler retail $150 IAS price $139.99 - Item Code: 810

Anacervix® 30x 420mg capsules retail $25 IAS price $22.49 - Item Code: 163

NEW: Anastrozole 28x 1mg tablets retail $149 IAS price $139.99 NEW: Anastro-Pro™ 28x 100mcg capsules retail $35 IAS price $32.49

Andro-Pro™

NEW: Andro-Pro™ 60 capsules retail $55 IAS price $49.99 - Item Code: 758

Aniracetam

NEW: Ani-Pro™ 20x 750mg capsules retail $35 IAS price $29.99 - Item Code: 777

Adenosine Triphosphate (see ATP)

Arginine (see Beyond GHS®; Nitric-Pro™), Argireline (see Crème-Pro™ Smoother), Arterial wave velocity (see Bio-Clip & Bio-Cuff)

Adrafinil

Artemisinin

NEW: Adra-Pro™ 40x 300mg capsules retail $60 IAS price $49.99 - Item Code: 775

Artem-Pro™ 90x 100mg capsules retail $25 IAS price $22.99 - Item Code: 642

Ascorbyl palmitate (see Crème-Pro™ Protector, Crème-Pro™ Smoother), Astaxanthin (see CrèmePro™ Protector), Astragalus extract (see TA65®)

Aglomelatine (see Valdoxan)

Aldosterone

Aldosterone 15x 125mcg capsules retail $105 IAS price $99.49 - Item Code: 687

Alfalfa (see Dr Gordon’s Organic Greens®), Allicin (see garlic), Alpha lipoic acid (see lipoic acid)

Aminoguanidine (pimagedine) Amino-Pro 100 x 75mg tablets retail $35 IAS price $29.99 - Item Code: 303

Aminohydroxybutyric acid (see GABOB), Aminophylline (see Crème-Pro™ Cellulite), Aminosyn (see Hair-Pro™), Amphoteric surfactants (see Nanogen® shampoo, Nanogen® conditioner)

ATP (Adenosine Triphosphate)

ATP-Boost™ 60x 20mg tablets retail $35 IAS price $29.99 - Item Code: 821 ATP-Boost™ (see ATP), Azilect® (see rasagiline)

B12 (vitamin B12) Beyond B12® 40x 2mg sublingual tablets retail $30 IAS price $29.99 - Item Code: 477 NEW: Cromatonbic® 8x1mg i.m.ampoules retail price $20 IAS price $17.49 Barley grass (see Dr Gordon’s Organic Greens®), BCI (see Beyond Chelation Improved®)

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B-Cure® laser 1 Unit

Bio-CUFF™

BEC5 Curaderm®

Bio-En’R-Gy C®

Beetroot (see Neo40®)

Bioflavonoids (see Wobenzym®), Biological age measurement (see Bio-CLIP™, PulmoLife®), Bioperine (see Bio-En’R-Gy®), Biotin (see Beyond B12®; Beyond Chelation Improved®, HRT Plus®; BCI; Nitric-Pro™), Blood oxygenation measurement (see Bio-CLIP™), Blood pressure measurement (see Bio-CUFF™), Blueberry extracts (see Andro-Pro™)

B-Cure® laser 1 Unit retail $795 IAS price $749.99 - Item Code: 850

BEC5 Curaderm® 20ml tube cream retail $140 IAS price $129.99 - Item Code: 403

Benfotiamine

Milgamma Mono® 30x 50mg tablets retail $25 IAS price $19.99 - Item Code: 273

Benzoic acid (see Gerovital®), Beta alistine (see L-carnosine), Beta glucan (see Beyond Chelation Improved®, Nanogen® serum), Betaine (see TMG), Beta sitosterol (see Beyond Chelation Improved®), Beyond Any Multiple® (see Beyond Chelation Improved®)

Beyond Chelation Improved® (BCI) Beyond Chelation Improved® 30 sachets retail $80 IAS price $79.99 - Item Code: 351

Beyond Clean® v2 (Calcium EDTA & Zeolite)

NEW: Beyond Clean® v2 32 oz. bath salts retail $70 IAS price $69.99 - Item Code: 881

Beyond Fiber®

Beyond Fiber® 504 grams powder retail $50 IAS price $49.99 - Item Code: 436

Beyond GHS®

Bio-CUFF® one complete kit retail $150 IAS price $124.99 - Item Code: 715

Bio En’R-Gy C® 200 grams powder retail $60 IAS price $59.99 - Item Code: 591

Boluoke® (Lumbrokinase)

NEW: Boluoke® 60 capsules retail price $108 IAS price $94.99 - Item Code: 839

Bone-Pro2™

NEW: Bone-Pro2™ 60 capsules retail $39 IAS price $32.99 - Item Code: 870

Borate (see Andro-Pro™, Can-C™), Boron (see Andro-Pro™, Beyond Chelation Improved®, BCI)

Bromocriptine

Parlodel® 30x 2.5mg tablets retail $25 IAS price $24.99 - Item Code: 58

Bromelain (see Digestif®, Wobenzym®), Buxamin (see GABOB), Calcium (see Bone-Pro™, BCI, Nitric-Pro™)

Cabergoline (Dostinex®)

Dostinex® 8x 0.5mg tablets retail $99 IAS price $92.49 - Item Code: 612

Beyond GHS® 75 tablets retail $90 IAS price $89.99 - Item Code: 353

Caffeine (see Crème-Pro™ Cellulite), Calcium (see Bone-Pro™, Beyond Chelation Improved®, Nitric-Pro™)

bFGF (see Hair-Pro™), BHT (butylhydroxytoluene, see ACF228™)

Can-C™ eye-drops

Bio-CLIP™

Can-C™ 2x 5ml vials retail $45 IAS price $39.99 - Item Code: 456

complete kit retail $1500 IAS price $1299.99 - Item Code: 653

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Can-C™ Plus

Can-C Plus™ 90 capsules retail $40 IAS price $34.99 - Item Code: 629

CoQ10SRTM (Coenzyme Q10, ubiquinol, biquinone)

NEW: CoQ10SRTM 30 x 100mg slow release capsules retail $30 IAS price $25.99 - Item Code: 824

Carboxymethylcellulose (see Can-C™) , Carbidopa (see Sinemet®), Carnosine (L-carnosine, see ACF228™, Can-C™, Can-C Plus™, L-carnosine), Catalase (see ACF228™)

Copper (see Beyond Chelation Improved®), Cortisol (cortisone, see Fludrocortisone, hydrocortisone), Cranberry extracts (see Andro-Pro™)

Centrophenoxine (meclofenoxane)

Crème-Pro™ Cellulite

Cerebrolysin®

Crème-Pro™ Moisturizer

Chlorella (see Dr Gordon’s Organic Greens®), Choline (see Beyond Chelation Improved®, centrophenoxine, krill), Chromium (see Beyond Chelation Improved®), Chromium polynicotinate (see ACF228™)

Crème-Pro™ Protector

Cialis® (tadalafil)

Crème-Pro™ Smoother

Cialis® 4x 20mg tablets retail $90 IAS price $82.49 - Item Code: 296

NEW: Crème-Pro™ Smoother 30ml pump cream retail $69 IAS price $59.99 - Item Code: 831

Ciproxin® (ciprofloxacin)

Cresote bush (see ACF228®, Digestif®)

Cent-Pro™ 60x 250mg tablets retail $35 IAS price $29.99 - Item Code: 243

Cerebrolysin® 5x 5ml i.m. ampoules retail $99 IAS price $94.99 - Item Code: 595

Ciproxin® 10x 500mg tablets retail $35 IAS price $32.49 - Item Code: 640

Citrus bioflavonoids (see Beyond Chelation Improved®), Cocos nucifera oil (see Nanogen® conditioner)

NEW: Crème-Pro™ Cellulite 30ml pump cream retail $34 IAS price $29.99 - Item Code: 828

NEW: Crème-Pro™ Moisturizer 30ml pump cream retail $44 IAS price $39.99 - Item Code: 829

NEW: Crème-Pro™ Protector 30ml pump cream retail $59 IAS price $49.99 - Item Code: 830

CurcuminSR™ (turmeric extract)

NEW: CurcuminSR™ (slow release) 30x 125mg capsules retail $25 IAS price $21.49 - Item Code: 841

Cycloastragenol (see TA65®), Cyclodextrin (see CoQ10SR™), Cyprenil® (see deprenyl)

Cobalt chloride

Cobalt 100x 200mcg tablets retail $55 IAS price $49.99 - Item Code: 646

D3 (vitamin D)

Coenzyme Q10 (see CoQ10)

NEW: D3-5000™ 100x 5000 IU capsules retail $20 IAS price $12.49 - Item Code: 843

Colchicine (Colcrys®)

NEW: D3-Pro2™ 12x 50,000 IU capsules retail $30 IAS price $24.99 - Item Code: 842

NEW: Colchicine 40x 1mg tablets retail $24 IAS price $19.99 - Item Code: 835

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Deprenyl (selegiline)

Jumex® 50x 5mg tablets retail $65 IAS price $54.99 - Item Code: 35

Dr. Gordon’s Organic Greens Organic best of greens® 10 oz. bottle powder retail $35 IAS price $34.99 - Item Code: 688

Dep-Pro™ 20ml/ 300mg liquid (HCL) bottle retail $90 IAS price $84.99 Item Code: 746

Dutasteride

Dercos® (aminexil)

Avodart® 30x 0.5mg tablets retail $89 IAS price $82.49 - Item Code: 276

Dercos® 200ml bottle shampoo retail $25 IAS price $22.99 - Item Code: 17

Desmopressin (also see

vasopressin)

Minurin® 2.5ml nasal spray retail $39 IAS price $34.99 - Item Code: 229

DHA (docosahexaenoic acid, see krill), Diapid® (see vasopressin)

Digestif™

Digestif® 60 capsules retail $20 IAS price $16.99 Item Code: 626

Di-IndolylMethane (DIM, see ACF228™, DIM-Pro™), DIM (see ACF228™, DIM-Pro™), Dimethicone (see Nanogen®)

DIM-Pro2™

Ebixa (see Memantine) EDTA (ethylene diamine tetraacetic acid, see Beyond Chelation Improved®, Beyond Clean®, Beyond Fiber®), Eldepryl® (see deprenyl), EPA (eicosapentaenoic acid, see krill), Ergoloid mesylate (see hydergine, nicergoline)

Esnatri™ cream (bio-identical triple estrogen cream)

Esnatri™ 50ml 100mg cream retail $55 IAS price $49.99 - Item Code: 25 Essential Daily Defence® (see Beyond Chelation Improved®), Estradiol (see Esnatri™), Estriol (see Esnatri™), Estrone (see Esnatri™)

Finesteride (also see Hair-Pro™) Finesteride generic 28x 5mg tablets retail $40 IAS price $37.49 - Item Code: 749

NEW: DIM-Pro2 ™ 100 capsules retail $50 IAS price $44.99 - Item Code: 844

Proscar® 15x 5mg tablets retail $45 IAS price $39.99 - Item Code: 67

DMAE (dimethylaminoethanol, see centrophenoxine, Crème-Pro™ Smoother), DMSA (dimercaptosuccinic acid, see ACF228™), DMSO (Dimethyl sulfoxide, see laetrile), Docosahexaenoic acid (see DHA), Dostinex® (see cabergoline)

Florinef® (see Fludrocortisone)

Doxycycline

Doxycycline 8x 100mg capsules retail $25 IAS price $22.49 - Item Code: 164

D-pantethine (see Can-C Plus™), D-panthenol (see Nanogen® conditioner)

Fluconazole (Diflucan)

Loitin® 7x 50mg capsules retail $39 IAS price $34.99 - Item Code: 307

Folic acid (folate, see ACF228™, Beyond Chelation Improved®, Beyond B12®; Dim-Pro2™, HRT Plus®, Lithium-Pro™, Nitric-Pro™), Forced Expiry Volume- Lungs (see PulmoLife®)

Fludrocortisone

Fludro-Pro™ 100x 20mcg tablets retail $20 IAS price $17.99 - Item Code: 759

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Fructoborate (see Andro-Pro™), GABA (gamma-aminohydroxybutyric acid, see Gamalate B6®, picamilone)

Glutathione (also see ACF228™

Breathe Easy)

Gabapentin

Advanced Cellular Glutathione® 2 oz. spray retail $45 IAS price $42.49 - Item Code: 832

GABOB (also see Gamalate®)

Gamibetal® 20x 500mg tablets retail $39 IAS price $34.99 - Item Code: 402

Glycerine (glycerin, see Can-C™), Glycosides (see BEC5 Curaderm®), Grape seed extracts (see Beyond Chelation Improved®, Resveratrol-Pro™), Green tea extracts (see Resveratrol-Pro™), Growth hormone (see HGH)

Galantamine (Reminyl®)

Hair-Pro™

Gamalate®

Hawthorne Berry (crataegus, see Beyond Chelation Improved®, Neo40®), Heart rate measurement (see Bio-CLIP™, Bio-CUFF™)

NEW: Neurontin® 100x 300mg capsules retail $39 IAS price $34.99 - Item Code: 875

Galantamine Pro 30x 8mg tablets retail $79 IAS price $69.99 - Item Code: 825

Gamalate B6® 60x 250mg tablets retail $24 IAS price $19.99 - Item Code: 27

Garlic (see see Beyond Chelation Improved®)

Gengigel® mouthwash

Gengigel® 150ml bottle liquid retail $20 IAS price $17.49 - Item Code: 550

NEW: Hair-Pro™ 2 oz. spray bottle retail $180 IAS price $169.99 - Item Code: 765

HemaGel®

NEW: HemaGel® 5 gram tube cream retail $20 IAS price $17.99 - Item Code: 820

Genotropin® (see HGH)

HGH (human growth hormone, somatropin, see IGF-1, Sermorelin, Beyond GHS®, GABOB, GHRP2, GHRP6), Humatrope® (see HGH), Hyaluronic acid (see Hyaluronan, Crème-Pro™ Protector, Gengigel®, Hair-Pro™, Novisyn®)

Gerovital-H3®

HRT Plus®(pueraria mirifica)

Gerovital-H3® 5x 5ml ampoules retail $59 IAS price $49.99 - Item Code: 258

Gerovital-H3® 25x 100mg tablets retail $35 IAS price $29.99 - Item Code: 29 GH3-Pro™ 60x 100mg tablets retail $20 IAS price $17.99 - Item Code: 360 GH (growth hormone, see HGH), Ginkgo biloba (see Beyond Chelation Improved®), Glucophage (see metformin)

GHRP2

NEW: GHRP2-Pro™ 120ml 120mg liquid bottle retail $180 IAS price $175.00 - Item Code: 872

GHRP6 (see Releasing-Pro™)

HRT Plus® 60 tablets retail $50 IAS price $49.99 - Item Code: 496

Hyaluronan (hyaluronic acid)

NEW: Novisyn® 30x 5ml liquid sachets retail $30 IAS price $25.99

Hydergine (ergoloid mesylate) Hydergine® 30x 4.5mg tablets retail $35 IAS price $29.49 - Item Code: 32

Hydrocortisone

Hydro-Pro® 100x 5mg capsules retail $35 IAS price $29.99 - Item Code: 760

Hydrogen (see Zeogold2®) www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

Idebenone (also see Crème-Pro™

Protector)

NEW: Ideb-Pro™ 60x 30mg capsules retail $29 IAS price $24.99 - Item Code: 492

NEW: Lith-Pro™ 60 capsules retail $25 IAS price $19.99 - Item Code: 717

IGF-1 (insulin like growth factor, see Hair-Pro™ also see Releasing-Pro™), Indol-3-Carbinol (I3C, see DIM)

L-methione (see ACF228™; Can-C Plus™), L-proline (see Nitric-Pro™), Lucidril® (see centrophenoxine), Lumbrokinase (see Boluoke®), Lupine extract (see Nanogen® serum)

Injection packs

L-tryptophan

Subcutaneous kit 30x pack retail $29 IAS price $24.99 - Item Code: 438

Lysine (see Nitric-Pro™)

Intramuscular kit 30x pack retail $29 IAS price $24.99 - Item Code: 439

Inosine (see Beyond GHS®), Inositol (see Beyond Chelation Improved®), Iodide (see ACF228™), Iodine (see ACF228™, Beyond Chelation Improved®), Isoflavonoids (see HRT Plus®), Ixel® (see milnacipran), Jerusalem artichoke (see Beyond Fiber®), Joint-Pro™ (see Hyaluronan), Jumex® (see deprenyl), Ketoconazole (see Nizoral®)

Krill

Krill 60x 500mg gel capsules retail $45 IAS price $39.99 - Item Code: 584

Laetrile (amygdalin; VitaB17®) Vita-B17 cream 50ml 1% retail $95 IAS price $87.49 - Item Code: 763

L-Tryp-Pro™ 50x 500mg capsules retail $20 IAS price $17.49 - Item Code: 666

Maca® (lepidium meyenii walp) Longevity Maca® 175 grams powder retail $40 IAS price $39.99 - Item Code: 851 Magnesium (see Andro-Pro™, Beyond Chelation Improved®, Bone-Pro2™, Digestif®, Gamalate B6®, Nitric-Pro™), Malic acid (see Beyond Chelation Improved®), Manganese (see Beyond Chelation Improved®), Mastic (see Digestif®), Meclofenoxane (see centrophenoxine)

Melatonin (Melatonin Zn Se®) MZS™ 60x 3mg tablets retail $30 IAS price $19.99 - Item Code: 701

Memantine (Namenda®; Ebixa®)

L-arginine (see arginine), Lasers (see B-Cure®, Vie-Light®)

Memantine-Pro™ 42x 10mg capsules retail $105 IAS price $89.99 - Item Code: 826

L-carnosine (also see ACF228™;

Melanocyte stimulating hormone (see MSH)

Can-C™; Can-C Plus™)

Carnosine 60x 250mg capsules retail $30 IAS price $24.49 - Item Code: 784 L-citrulline (see Neo40®), L-cysteine (see Nanogen® conditioner), L-dopa (see Sinemet®), Lecithin (see Crème-Pro™ Cellulite), Levodopa (see Sinemet™), L-histidine (see Can-C Plus™), Lemon grass (see Dr Gordon’s Organic Greens®), Licorice (see Beyond GHS®, Digestif®), Lipoic acid (alpha version see Beyond Chelation Improved®; R-version see ATP-Boost™)

Lithium

Metformin (Glucophage®) Dianben® 50x 850mg tablets retail $29 IAS price $24.99 - Item Code: 382 Metforal® 50x 500mg tablets retail $25 IAS price $22.99 - Item Code: 42 NEW: Metformin SR® 56x 500mg tablets retail $30 IAS price $27.99 - Item Code: 874 Methione (see Beyond Chelation Improved®), Milk Protein (see Bone-Pro2™)

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

Nanogen® serum

Milnacipran (Savella®)

Ixel® 56x 50mg tablets retail $80 IAS price $74.99 - Item Code: 400

Minerals (general, see Quinton®), Minoxidil (see MinSaw™)

Nanogen® shampoo

MinSaw™

MinSaw™ 30ml bottle topical liquid retail $45 IAS price $39.99 - Item Code: 728

Miroestrol (see HRT Plus®), Mito-Pro™ (see ATP-Boost™)

Moclobemide (Manerix®) Moclamine® 30x 150mg tablets retail $35 IAS price $29.99 - Item Code: 39

Modafinil (also see adrafinil) Alertec® 30x 100mg tablets retail $180 IAS price $169.99 Modiodal® 30x 100mg tablets retail $160 IAS price $149.99 Provigil® 30x 100mg tablets retail $200 IAS price $189.99 Note: This product is only available via faxed orders, please use order form at the rear of this magazine. Molybdenum (see Beyond Chelation Improved®), MSM (methylsulfonomethane, see Beyond Chelation Improved®, Bio-En’R-Gy®, Nitric-Pro™), N-acetylcarnosine (see Can-C™), N-acetylcysteine (see ACF228™, Can-C™ Plus), NADH (Nicotinamide adenine dinucleotide, see Crème-Pro™ Moisturizer, PQQ)

MSH (melanocyte stimulating hormone) NEW: MSH2-Pro™ 5ml 500IU nasal spray retail $79 IAS price $69.99

Naltrexone (Navcol®)

Naltrex-Pro™ 30x 4.5mg capsules retail $70 IAS price $59.99 - Item Code: 637

Namenda® (see Memantine)

Nanogen® conditioner

Nanogen® 30ml serum dropper MEN retail $55 IAS price $54.99 - Item Code: 890 Nanogen® 30ml serum dropper WOMEN retail $55 IAS price $54.99 - Item Code: 891

Nanogen® 240ml tube conditioner MEN retail $20 IAS price $19.99 - Item Code: 886 Nanogen® 240ml tube conditioner WOMEN retail $20 IAS price $19.99 - Item Code: 887

Nanogen® 240ml tube shampoo MEN retail $18 IAS price $17.99 - Item Code: 888 Nanogen® 240ml tube shampoo WOMEN retail $18 IAS price $17.99 - Item Code: 889

Needles (see injection packs), Neurontin® (see Gabapentin), Nettle root extract (see Prostate-Pro™)

Neo40®

Neo40 Daily® 30x lozenges retail $60 IAS price $59.99 - Item Code: 790

Nettle root extract (see Prostate-Pro™)

Neydent toothpaste

Neydent toothpaste 50ml tube retail $18 IAS price $15.99 - Item Code: 118

Niacin (nicotinate, niacinamide, see vitamin B3)

Nicergoline

Sermion® 50x 10mg tablets retail $50 IAS price $47.49 - Item Code: 489

Nitric Oxide Saliva Test Strips Neo40® 10 saliva strips $25 IAS price $24.99 Item Code: 866

Nitric-Pro™

Nitric-Pro™ 225 grams powder retail $40 IAS price $36.99 - Item Code: 792

Nizoral® shampoo (2% ketoconazole) Nizoral® 60ml bottle shampoo retail $15 IAS price $12.99 - Item Code: 437

Novisyn Hyaluronic Acid

Novisyn Hyaluronic Acid 30 x 5ml liquid sachets retail $30 IAS price $25.99 - Item Code: 900

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Nordihydroguaiaretic acid (NDGA, see ACF228™, Digestif®), Norditropin® (see HGH), Oat grass (see Dr Gordon’s Organic Greens®), Omega 3 (see Beyond Chelation Improved®, krill), Omega 6 (linoleic acid, GLA, see Beyond Chelation Improved®, krill), Omega 9 (oleic acid, see Beyond Chelation Improved®, krill), Oxythiocynate (OCSN, thiocynates, see 1st Line™)

Oxytocin

Oxy-Sub™ 24x 20 IU sublingual troches retail $85 IAS price $79.99 - Item Code: 660

NEW: Oxy-Pro® 5ml 500 IU nasal spray retail $65 IAS price $59.99 - Item Code: 823 PABA (para-aminobenzoic acid, see Beyond Chelation Improved®, Gerovital®), Palmitate (see Beyond Chelation Improved®), Pancreatin (see Wobenzym®), Panthenol (pantothenic acid, see vitamin B5), Papain (see Beyond Chelation Improved®, Wobenzym®)

PEMF (Pulsed electronic magnetic field) Please contact us for the range of professional equipment currently available. Further details are available at www.pemf-therapy.eu

Penicillin (Penilevel®)

Penilevel® 30x 250mg sachets powder retail $35 IAS price $32.99 - Item Code: 206

Pentavita (see Nanogen®)

Peptide Bioregulators NEW: Adrenals (Glandokort®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 853 NEW: Blood vessels (Ventfort®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 868 NEW: Bone Marrow (Bonomarlot®) 20x 200mg capsules retail $90 IAS price $79.99

NEW: Kidneys (Pielotak®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 869 NEW: Liver (Svetinorm®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 894 NEW: Lungs (Taxorest®) 20x 200mg capsules retail $90 IAS price $79.99 NEW: Muscle (Gotratix®) 20x 200mg capsules retail $90 IAS price $79.99 NEW: Parathyroid (Bobothyrk®) 20x 200mg capsules retail $90 IAS price $79.99 NEW: Pancreas (Suprefort®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 892 NEW: Pineal (Endoluten®) 20x 200mg capsules retail $115 IAS price $99.99 - Item Code: 884 NEW: Prostate (Libidon®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 854 NEW: Testes (Testoluten®) 20 x 200mg capsules retail $90 IAS price $79.99 - Item Code: 855 NEW: Thyroid (Thyreogen®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 883 NEW: Stomach (Stamacort®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 896 NEW: Heart (Cheloheart®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 898 NEW: Bladder (Chitomur®) 20 x 200mg capsules retail $90 IAS price $79.99 - Item Code: 897

NEW: Brain (Cerluten®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 867

NEW: Ovaries (Zhenoluten®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 899

NEW: Cartilage (Sigumir®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 893

NEW: Thymus (Vladonix®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 882

NEW: Eyesight (Visoluten®) 20x 200mg capsules retail $90 IAS price $79.99 - Item Code: 856 40

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Phenytoin (Dilantin®, Epanutin®)

Pramiracetam

Phosphatidylcholine (see Beyond Chelation Improved®, Crème-Pro™ Cellulite), Phosphatidylserine (see Beyond Chelation Improved®), Phospholipids (see krill), Phosphorous (see Nitric-Pro™)

Pregnenolone

Phen-Pro™ 30x 25mg capsules retail $25 IAS price $19.99

Pramiracetam 40x 300mg tablets retail $60 IAS price $49.99 - Item Code: 451 Pregnenolone 50x 100mg capsules retail $25 IAS price $19.99 - Item Code: 335

Procaine (Novocain®, see Gerovital®, Crème-Pro™ Moisturizer)

Phosphatidlyserine

Phos Pro 60x 100mg capsules retail $55 IAS price $47.49 - Item Code: 692

Picamilone

Pic-Pro™ 60x 50mg tablets retail $25 IAS price $17.99 - Item Code: 184

Progesterone

Progesterone 50ml 2.5 grams cream retail $35 IAS price $29.99 - Item Code: 789

Propranolol (Inderal®)

Pimagidine (see aminoguanidine)

Inderal® 30x 40mg tablets retail $25 IAS price $19.99 - Item Code: 34

Piracetam (also see Anacervix®)

Prostate-Pro2™

Nootropil® 20 grams 100ml liquid retail $25 IAS price $21.49 - Item Code: 50 Nootropil® 60x 800mg tablets retail $30 IAS price $27.99 - Item Code: 205 Pira-Pro™ 100x 800mg tablets retail $24 IAS price $17.99 - Item Code: 873

Pueraria mirifica (see HRT Plus®), Pulsed electronic magnetic field (see PEMF) Pulsed magnetic therapy (PMT, see PEMF), Pygeum africanum (see Nanogen®, Prostate-Pro2™)

PMT 100 1 kit

Pyridoxamine

PMT 100 1 kit IAS price $24,000.00 - Item Code: 801

NEW: Prostate-Pro2™ 60 capsules retail $35 IAS price $29.99

Pyridox-Pro™ 60x 50mg tablets retail $35 IAS price $29.99 - Item Code: 449

Polyphenols (see grape seed extract), Pomegranate extracts (see Andro-Pro™), Potassium (see Beyond Chelation Improved®, Gerovital®), Potassium iodide (see ACF228™), Potassium iodine (see ACF228™)

Pyritinol

PQQ (pyroloquinoline quinone)

Pyroloquinoline quinone (see PQQ), Quercetin (see Digestif®, Resveratrol-Pro™)

NEW: PQQ-Pro™ 30x 20mg capsules retail $40 IAS price $35.99 - Item Code: 837

Pueraria mirifica (see HRT Plus®)

PulmoLife®

PulmoLife®1 Spirometer + 4 tubes retail $160 IAS price $139.99 - Item Code: 781 PulmoLife®25 additional tubes retail $25 IAS price $19.99 - Item Code: 787

Cerbon 6® 60x 100mg tablets retail $25 IAS price $21.49 - Item Code: 167

Quinton®

Isotonic® 24 oral ampoules retail $40 IAS price $34.99 - Item Code: 681 Hypertonic® 24 oral ampoules retail $40 IAS price $34.99 - Item Code: 682

Rasagiline

NEW: Rasagiline-Pro™ 30x 1mg capsules retail $95 IAS price $89.99 - Item Code: 827

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Reboxetine (Davedax®)

Scalproller®

Red algae (carrageenan, see Beyond Chelation Improved®), Red clover herb extract (see Prostate-Pro2™), Red yeast (see Beyond Chelation Improved®)

Selepryl® (see deprenyl), Selegiline (see deprenyl), Selenium (see ACF228™, Beyond Chelation Improved®, Dim-Pro2™, MZS™, Prostate-Pro2™, thymus)

Edronax® 60x 4mg tablets retail $69 IAS price $62.49 - Item Code: 22

Releasing-Pro™

Scalproller® 0.3mm roller kit retail $75 IAS price $69.99 - Item Code: 762

Sermorelin

NEW: Releasing-Pro™ 5ml 500IU nasal spray retail $89 IAS price $79.99

Sermo-Pro® 30ml/ 30mg liquid bottle retail $215 IAS price $199.99 Item Code: 714

Reminyl® (see Galantamine), Resveratrol (see ACF228™, Beyond Chelation Improved®, Crème-Pro™ Protector, MinSaw™, Resveratrol-Pro™)

Shave grass (see Dr Gordon’s Organic Greens®), Silicon/ Silica (see Beyond Chelation Improved®; Nanogen™, Wobenzym®)

Resveratrol-Pro™

Silver protein (ACS®)

Resveratrol-Pro™ 60 capsules retail $30 IAS price $24.99 - Item Code: 647

Retin-A®

Retirides® 30ml 0.025% cream retail $39 IAS price $29.99 - Item Code: 254 Retirides® 30ml 0.050% cream retail $49 IAS price $39.99 - Item Code: 764 Retirides® 30ml 0.100% cream retail $59 IAS price $49.99 - Item Code: 74 Retin-A® 20ml 0.100% micro-gel retail $79 IAS price $72.49 - Item Code: 744

Retinolic acid (tretinoin, see MinSaw™, Retin-A®), Ribonucleic acids (RNA, see Cerebrolysin®, NeyDent®), Ribose (see Bio-En’R-Gy®), Rice bran husks (see Beyond Fiber®), R-lipoic acid (see ATP-Boost™)

Roxithromycin

Rulid® 10x 50mg tablets retail $29 IAS price $24.99 - Item Code: 635

Rutin (see Wobenzym®), Saizen® (see HGH), Salicylic acid (see BEC5 Curaderm®, Nanogen® shampoo)

SAMe (S-Adenosyl-L-Methionine) SAMYR® 20x 400mg enteric-coated tablets retail $69 IAS price $62.49 - Item Code: 231 Saw palmetto (Serena repens, see MinSaw™; Nanogen®, Prostate-Pro2™)

Advanced Cellular Silver 200® 2 oz. spray retail $39 IAS price $34.99 - Item Code: 596

Sinemet® (l-dopa & carbidopa)

Sinemet® 50x 100mg tablets retail $59 IAS price $54.99 - Item Code: 596

Solasodine glycosides (see BEC5 Curaderm®), Somatomedin C (see IGF-1), Somatropin (see HGH), Spirulina (see Dr Gordon’s Organic Greens®)

Stablon® (tianeptine)

Stablon® 60x 12.5mg tablets retail $69 IAS price $62.49 - Item Code: 748

Stevia (see Dr Gordon’s Organic Greens®), Superoxide dismutase (SOD, see Nanogen® serum), Syringes (see injection packs)

TA65®

TA65® 30 capsules IAS price $218.99 - Item Code: 755 TA65® 90 capsules IAS price $599.99 - Item Code: 754

Tamanu Tamanu 50ml bottle oil retail $29 IAS price $24.99 - Item Code: 724 Telomeres/ telomerase (see TA65®), Temple viper venom (synthetic, see Crème-Pro™ Smoother)

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Tetracycline

Ambramicina® 16x 250mg tablets retail $25 IAS price $22.49 - Item Code: 143

Thymus (also see peptide bioregulator)

Thym-Uvocal® 90x 200mg capsules retail $115 IAS price $99.99 - Item Code: 691

Thyroid (also see peptide bioregulator)

NEW: NatureThroid® 1¼ grain 100x 75mg tablets retail $49 IAS price $44.99 - Item Code: 902 NEW: NatureThroid® 1½ grain 100x 90mg tablets retail $55 IAS price $47.99 - Item Code: 901 NEW: NatureThroid® 1¾ grain 100x 105mg tablets retail $59 IAS price $52.99 - Item Code: 903 NatureThroid® 2 grain 100x 120mg tablets retail $69 IAS price $59.99 - Item Code: 460

Our natural thyroids include: Armour® 100x 15mg tablets retail $49 IAS price $44.99 - Item Code: 411

Our synthetic thyroids include:

Armour® 100x 30mg tablets retail $59 IAS price $49.99 - Item Code: 468

NEW: IBSA® 25 tablets (21.4mcg T3 and 74mcg T4) retail $39 IAS price $34.99 - Item Code: 778

Armour® 100x 60mg tablets retail $69 IAS price $59.99 - Item Code: 7

Tiromel® (T3) 100x 25 mcg tablets retail $49 IAS price $44.99 - Item Code: 811

Armour® 100x 90mg tablets retail $89 IAS price $79.99 - Item Code: 594

Eutirox® (T4) 84x 100mcg tablets retail $29 IAS price $24.99 - Item Code: 662

Armour® 100x 120mg tablets retail $99 IAS price $89.99 - Item Code: 410 ERFA 100x 30mg tablets retail $45 IAS price $39.99 - Item Code: 736 NEW: ERFA 500x 30mg tablets retail $150 IAS price $129.99 - Item Code: 876 ERFA 100x 60mg tablets retail $60 IAS price $54.99 - Item Code: 737 NEW: ERFA 500x 60mg tablets retail $195 IAS price $179.99 - Item Code: 877 ERFA 100x 125mg tablets retail $90 IAS price $84.99 - Item Code: 738 NEW: ERFA 500x 125mg tablets retail $260 IAS price $249.99 - Item Code: 878 NatureThroid® 100x 15mg tablets retail $34 IAS price $29.99 - Item Code: 613 NatureThroid® 100x 30mg tablets retail $39 IAS price $32.99 - Item Code: 613 NatureThroid® 100x 60mg tablets retail $44 IAS price $37.99 - Item Code: 323

Thyrotropin releasing hormone (see TRH), TMG (trimethylglycine, betaine, see Beyond Chelation Improved®, Bio-En’R-Gy®), Tocotrienols (see Beyond Chelation Improved®), Tribulus terrestris (see Andro-Pro™, Beyond GHS®)

TRH (thyrotropin releasing hormone)

NEW: Abaris™ 20 x 5mg sublingual tablets retail $240 IAS price $199.99 - Item Code: 793

Trypsin (see Wobenzym®), TRX (see Hair-Pro™), Turmeric (see curcumin), Ubiquinol (see CoQ10), Ubiquinone (see CoQ10), Urea (see BEC5 Curaderm®), Urtica dioica (see Nanogen®)

Valdoxan® (agomelatine)

Valdoxan® 28x 25mg tablets retail $150 IAS price $139.99 - Item Code: 690

Vasopressin (also see desmopressin)

NEW: Vaso-Pro® 5 ml 500 IU nasal-spray retail $75 IAS price $69.99 - Item Code: 838

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VEGF (see Hair-Pro™, Nanogen® conditioner, Nanogen® serum, Nanogen® shampoo)

Venlafaxine (Efexor®)

Venlafaxine 28x 37.5mg tablets retail $45 IAS price $39.99 - Item Code: 488

Viagra® (sildenafil)

Viagra® 4x 100mg tablets retail $85 IAS price $79.99 - Item Code: 90

Vielight® laser

NEW: Vielight® 633 inter-nasal laser retail $299 IAS price $298.99 - Item Code:

Vincamine (see Anacervix®)

Vinpocetine

Intelectol® 50x 5mg tablets retail $19 IAS price $15.99 - Item Code: 91

Vitamin A (beta carotene, palmitate, see Beyond Chelation Improved®), Vitamin B1 (thiamine, see Beyond Chelation Improved®, Nitric-Pro™), Vitamin B1 (see benfotiamine), Vitamin B2 (riboflavin, see Beyond Chelation Improved®, Nitric-Pro™), Vitamin B3 (niacin, niacinamide, see Beyond Chelation Improved®, CrèmePro™ Cellulite, Nanogen® serum, Nitric-Pro™, picamilone; Xan-Pro™), Vitamin B5 (panthenol, pantothenic acid, see Beyond Chelation Improved®, Nitric-Pro™), Vitamin B6 (pyridoxine, see ACF228™, Andro-Pro™, Beyond B12®, Beyond Chelation Improved®, DIM-Pro2™, Gamalate B6®; HRT Plus®, Nanogen®; Nitric-Pro™), Vitamin B6 (see pyridoxamine), Vitamin B12 (cobalamin, see B12®, Beyond Chelation Improved®, CrèmePro™ Moisturizer, Cromatonbic®, DIM-Pro2™), Lithium, Neo40®), Vitamin D3 (cholecalciferol, see D3, Beyond Chelation Improved®, Bone-Pro2™, Prostate-Pro2™), Vitamin C (ascorbic acid, see Beyond Chelation Improved®, Bio-En’R-Gy C®, Digestif®; MinSaw™, Neo40®, Nitric-Pro™)

Vitamin E (tocopherols, see Beyond Chelation Improved®, Can-C Plus™, DIM-Pro2™, Nitric-Pro™, Prostate-Pro2™, Resveratrol-Pro™), Vitamin K2 (menatretrenone, see Beyond Chelation Improved®, Bone-Pro2™), Wheat grass (see Dr Gordon’s Organic Greens®)

Wobenzym-N®

Wobenzym® 200 tablets retail $75 IAS price $72.49 - Item Code: 381

Wormwood (see artemisinin)

Xan-Pro® (xanthinol nicotinate) Xan-Pro® 50x 150mg tablets retail $20 IAS price $17.99 - Item Code: 552

Yohimbine (also see Crème-Pro™

Cellulite)

Plain Prowess® 100x 5mg tablets retail $59 IAS price $49.99 - Item Code: 94

Zeolite

NEW: ZeoGold2® (zeolite and hydrogen) 30 capsules retail $60 IAS price $59.99 - Item Code: 684

Advanced Cellular Zeolite®2 oz. spray retail $40 IAS price $42.49 - Item Code: 833 Zinc (see Andro-Pro™, Beyond Chelation Improved®, Can-C Plus™, MZS™, Nanogen® shampoo, Thym-Uvocal®) DIDN’T FIND WHAT YOU WERE LOOKING FOR? PLEASE CONTACT US WITH YOUR REQUIREMENTS.

Vitamin C test strips (Vitacheck-C®) NEW: Vitacheck-C® 50 strips retail $15 IAS price $14.99 - Item Code: 774

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Condition cross reference list This cross-reference list highlights individual products that have been used to treat & prevent various aging disorders. Note: It does not mean that all these products are synergistic together.

Free radical: ACF228™ Glycation: Aminoguanidine Hayflick: L-carnosine, TA65® Membrane: Centrophenoxine Mitochondrial: Hydergine, PQQ Neuroendocrine: Metformin, TRH Rotational: Melatonin Telomeres: TA65®

Antibiotics (also see influenzas & infections) Ciproxin, doxycycline, penicillin, roxithromycin, tetracycline

Anti-depressants (also see depression & wellbeing)

Lithium-Pro™, milnacipran (Ixel®), moclobemide (Manerix®), reboxetine (Edronax®), Stablon®, Valdoxan®, venlafaxine (Efexor®)

Anti-glycation (see AGE)

Adaptogens

HRT Plus®, maca, Quinton®

Anti-inflammatory (see inflammation)

Addison’s disease

Anti-oxidants (free radical scavengers)

ADHD (ADD, attention deficit disorder, see mental stimulants)

Anxiety (see stress)

Adrenal fatigue

ARMD (see eyesight)

Aldosterone, Peptide Bioregulator- Glandokort®

Aldosterone, hydrocortisone, Peptide Bioregulator Glandokort®

AGE (Advanced Glycated End Products, cross linking of proteins)

ACF228™, aminoguanidine, Can-C Plus™, L-carnosine, metformin, pyridoxamine

Age Related Macular Degeneration (see eyesight)

ACF228™, Active H-minus®, ATP-Boost™, Bio-En’RGy®, glutathione, idebenone, melatonin, pyritinol

Aromatase inhibitors

Anastrozole (Arimidex®), Beyond HRT®, DIM-Pro2™, progesterone

Arterial (See heart, arterial & blood) Arthritis (rheumatoid & osteo)

Gerovital-H3®, krill, Novisyn®, pregnenolone, pyritinol, SAMe, thymus, Wobenzym®

Age Related Mental Decline (see cognitive)

Asthma (see Allergies)

Aids (see HIV)

Autism (also see chelation agents)

Alcoholism (also see compulsive disorders) 5HTP, L-tryptophan, memantine

Oxytocin, piracetam

At-home therapeutic kits

B-Cure® laser, Vielight® laser

Allergies

Bio-En’R-Gy C®, pregnenolone, Thymus, Wobenzym®

Back Problems (see spine)

ALS (amyotrophic lateral sclerosis, see Lou Gehrig’s disease)

Bell’s palsy

Alzheimer’s (see senile dementia)

Beta blockers

Amino acids (including di-peptides)

5HTP, ACF228™, ATP-Boost™, Beyond GHS®, L-carnosine, L-tryptophan, Nitric-Pro

Beyond B12® Propranolol

Biological age measurement Bio-CLIP™, PulmoLife®

Anabolic (see growth hormone & testosterone)

Blood disorders (see heart, arterial & blood)

Anginas (see heart, arterial & blood)

Blood pressure

Animal use

Can-C™ eye-drops, deprenyl, L-tryptophan, peptide bioregulators

Antiaging (as impacting on a particular theory of aging) Calorie Restriction: L-carnosine, metformin, resveratrol

Neo40®, Nitric-Pro™, oxytocin, propranolol, vinpocetine

Bone problems (also see joints & arthritis)

Andro-Pro™, Bone-Pro2™, Esnatri™, Peptide Bioregulator - Bonomarlot®, progesterone, SAMe, thyroid

Breathing (see Lungs)

www.antiaging-systems.com // Order hotline: 1-866-800-4677 // e-mail: ias@antiaging-systems.com

Cancer (also see anti-oxidants & radiation)

1st Line™, anastrozole (Arimidex®), artemisinin, BEC5® Curaderm, Bio-En’R-Gy C®, bromocriptine, CurcuminSR™, D3, DIM-Pro2™, HRT Plus®, laetrile, melatonin, metformin, naltrexone, progesterone, Resveratrol-Pro™, thymus, TRH, Wobenzym®

Acarbose, aminoguanidine, ATP-Boost™, benfotiamine, krill, L-carnosine, metformin, Nitric-Pro™, Peptide Bioregulator- Suprefort®, pyridoxamine, TRH, thyroid

Diabetes insipidus (see urination)

Cardiovascular (see heart & arterial disorders)

Diagnostic products (see at-home diagnostics)

Cataplexy (sudden fatigue)

Dieting (See weight loss)

Adrafinil, modafinil, picamilone

Cataract (also see eyesight) Can-C™, Can-C Plus™

Digestive issues

Beyond Fiber®, Digestif®, Dr. Gordon’s organic greens®, Peptide Bioregulator - Stamakort®

Central Nervous System (CNS)

DNA support (also see telomeres)

Chelation agents (removing heavy metals, also see detox)

Down’s syndrome

Peptide Bioregulator - Cerluten®

Beyond Chelation Improved®, Beyond Fiber®, Bio-En’RGy C®, centrophenoxine, Dr. Gordon’s organic greens®, L-carnosine, zeolite

Cholesterol (see blood disorders) Crohn’s disease Naltrexone

Chronic fatigue syndrome (see mental stimulants & physical energy improvement) Cognitive (also see memory & senile dementias) Alertness: Adrafinil, modafinil Creativity: Aniracetam, piracetam, pramiracetam Focus/ concentration: Deprenyl, desmopressin, phosphatidylserine, vasopressin Energy: ATP-Boost™, centrophenoxine, picamilone General support: Gerovital-H3®, vinpocetine Intelligence: Hydergine Work load: Hydergine, thyroid

Compulsive disorder treatment (also see alcoholism)

5HTP, Gamalate®, L-tryptophan, picamilone

Cortisol alteration (also see stress)

Aldosterone, fludrocortisone, GABOB, Gamalate®, hydrocortisone, Peptide Bioregulator - Glandokort®, Gerovital-H3®, phenytoin

Cross linking (see AGE) Deep vein thrombosis (see frequent fliers) Dental (see teeth & gums) Depression (also see well-being & anti-depressants) 5HTP, aniracetam, ATP-Boost™, CurcuminSR™, D3, deprenyl, Gerovital-H3®, Lithium, L-tryptophan, milnacipran, picamilone, piracetam, pramiracetam, pregnenolone, SAMe, thymus, thyroid

Detox (also see chelation agents)

Artemisinin, Bio-En-R-Gy C®, Beyond Clean®, Beyond Fiber®, DIM-Pro2™, Dr. Gordon’s organic greens®, zeolite

DHT alteration (dihydrotestosterone)

Dutasteride, finasteride, Hair-Pro™, MinSaw™, Nanogen’s®, Peptide Bioregulator - Libidon®, progesterone

Diabetes

CoQ10, D3, krill, L-carnosine, Peptide Bioregulators, PQQ, Resveratrol-Pro, TA65® Melatonin, piracetam

Dr. Gordon’s recommend products

Beyond B12®, Beyond Chelation Improved®, Beyond Clean2®, Beyond Fiber®, Beyond GHS®, Bio En’R-Gy C®, Dr Gordon’s Organic Greens®, HRT Plus®, maca, silver protein, zeolite

Dr. Pierpaoli’s recommend products Melatonin, TRH

Dr. Wright’s recommend products Esnatri, cobalt chloride, progesterone

Energy improvement (see physical energy & mental stimulants)

Enzymes

Boluoke®, Wobenzym®

Epilepsy

GABOB, Gamalate®, phenytoin

Erectile dysfunction (also see sex-libido & premature ejaculation)

Andro-Pro™, cabergoline, Cialis®, Neo40®, Nitric-Pro™, oxytocin, Viagra®, yohimbine

Estrogen alteration (both increases & decreases)

Anastrozole (Arimidex®), cobalt chloride, DIM-Pro2™, Esnatri™, HRT Plus®, progesterone

Eyesight (also see cataract, ARMD & glaucoma)

ARMD: MZS™ Cataracts: Can-C™, Can-C™ Plus Contact lenses: Can-C™ Dry eyes: Can-C™ General support: Aminoguanidine, Peptide Bioregulator - Visoluten®, vinpocetine Glaucoma: Can-C™ Retinal: MZS™, nicergoline, picamilone

Excitotoxins (reduction)

Deprenyl, idebenone, L-carnosine, Lithium, memantine

Fertility

Melatonin, metformin, Peptide Bioregulator - Zhenoluten®, TRH

Fibromyalgia (also see physical energy & mental stimulants & pain relief)

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1st Line, milnacipran, naltrexone, oxytocin

First Aid cabinet

1st Line™, melatonin, naltrexone, Thymus

1st Line™, HemaGel®, silver protein

Free radical scavengers (see anti-oxidants) Frequent fliers

1st Line, artemisinin, GABOB, Gamalate®, L-tryptophan, melatonin, Neo40®, Nitric-Pro™, picamilone, piracetam, pregnenolone, Resveratrol-Pro™, silver protein

Gastrointestinal (see digestive) Glaucoma (see eyesight) Glucose control (see diabetes) Glycation prevention (see AGE)

HGH (see growth hormone) Homocysteine (see blood disorders) Hormones (includes hormonal support supplements)

Bio-identical: Aldosterone, Esnatri™, melatonin, MSH, oxytocin, pregnenolone, progesterone, TRH Natural (animal): Armour® thyroid, ERFA® thyroid, Nature® thyroid, thymus, vasopressin, West® thyroid Synthetic: Desmopressin, Eutirox® thyroid, fludrocortisone, hydrocortisone, IBSA® thyroid, Tiromel® thyroid Supporting agents: Peptide Bioregulators, Cobalt chloride, DIM-Pro2™, GHRP2, GHRP6, sermorelin

HRT (hormone replacement therapy for women)

Gout

Cobalt chloride, Esnatri™, HRT Plus®, melatonin, progesterone

Colchicine

Growth hormone (improvement)

Beyond GHS®, bromocriptine, deprenyl, GABOB, Gamalate®, GHRP2, GHRP6, hydergine, Neo40®, NitricPro™, sermorelin, thymus, thyroid

Hemorrhoids

Human growth hormone (see growth hormone) Hydrogen

Active H-minus®, ZeoGold2®

Hypertension (see blood pressure)

Nitric-Pro™

Immune system improvement (also see infections)

Hair improvement

Dercos®, dutasteride, finasteride, Gerovital-H3®, HairPro™, krill, MinSaw™, Nanogen’s, Nitric-Pro™, Nizoral®

Headaches (see migraines) Health diagnostics (see at home test kits) Hearing disorders

Aldosterone, Anacervix®, fludrocortisone, nicergoline, picamilone, vinpocetine

Heart, arterial & blood (includes blood markers)

Arteries (hard): Aminoguanidine, Bio-CLIP™, BioCUFF™, L-carnosine, Resveratrol-Pro™ Blood pressure (high): Neo40®, Nitric-Pro™, Propranolol, vinpocetine Calcium: Peptide Bioregulator - Bobothyrk® Cholesterol (high): Beyond B12®, Beyond Fiber™, CoQ10, Gerovital-H3®, TRH, Xan-Pro™ Dilation (nitric-oxide): Neo40®, Nitric-Pro™, Vielight® Fibrinogen: CurcuminSR™, TRH, Wobenzym® General support: CoQ10, krill, Peptide Bioregulators Chelohart® & Ventfort®, PQQ, vinpocetine, Wobenzym® Glucose (high): Acarbose, metformin, TRH Glycated end-products: Aminoguanidine, metformin Heart pulse (irregular): ATP-Boost™, Bio En’R-Gy C®, thyroid Heavy metals (chelate): Beyond Chelation Improved®, Beyond Fiber®, Bio En’R-Gy C® Homocysteine: Beyond B12®, Beyond Chelation Improved®, Bio En’R-Gy C®, TRH Lipofuscin: Centrophenoxine Plaques (clots): Boluoke® Triglycerides: Bio En’R-Gy C®, CurcuminSR™, krill, TRH

Hepatitis (see liver and infections) Herpes (also see anti-biotics)

HIV (also see immune system improvement)

1st Line™, ATP-Boost™, Beyond B12®, L-carnosine, maca, melatonin, Peptide Bioregulator- thymus (Vladonix®), Peptide Bioregulator- thyroid (Thyreogen®), pyritinol, Resveratrol-Pro™, thymus, thyroid

Infections (also see immune system improvement, anti-biotics & influenzas) 1st Line™, artemisinin, fluconazole, silver protein, Wobenzym®

Inflammation (reduction)

Beyond Chelation Improved®, Bio-En’R-Gy®, Boluoke®, CurcuminSR™, Digestif®, Dr. Gordon’s organic greens®, krill, maca, pregnenolone, thymus, Wobenzym®

Influenzas (also see anti-biotics, infections & immune system improvement) 1st Line™

Injectable products

Cerebrolysin®, Cromatonbic® (B12), Gerovital-H3®

Insulin & glucose control (see diabetes) Intestinal flora (see probiotics) Inter-nasal products

Desmopressin (Minirin®), MSH (MSH2-Pro™), oxytocin (Oxy-Pro™), GHRP6 (Releasing-Pro™), vasopressin (Vaso-Pro™), Vielight® laser

Joints (also see bones & arthritis)

Boluoke®, krill, Peptide Bioregulator- Sigumir®, Novisyn®, pregnenolone, SAMe, thymus, Wobenzym®

Kidney disorders (also see infections)

Aminoguanidine, Peptide Bioregulator - Pielotak® SAMe, TRH

1st Line™, ACF228™, silver protein, Wobenzym®

Learning (also see memory & mental stimulants)

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Aniracetam, desmopressin, hydergine, piracetam, pramiracetam, vasopressin

Libido (see sex) Lipids (see blood disorders) Liver disorders (also see infections)

CoQ10, Idebenone, Peptide Bioregulator- Svetinorm®, pregnenolone, SAMe, silver protein

Longevity enhancement (significant lifespan increases seen in animal studies)

Centrophenoxine, deprenyl, Desmopressin, melatonin

Lou Gehrig (ALS) Naltrexone, TRH

Lungs

ACF228™ Breathe-Easy, Centrophenoxine, Nitric-Pro™, Peptide Bioregulator - Taxorest®, PulmoLife®

Lupus

Milnacipran, naltrexone

Lyme’s

1st Line™, silver protein

Macular degeneration (see ARMD & eyesight) Malaria (also see anti-biotics) Artemisinin

Menopause (see HRT) Mental stimulants (also see physical stimulants) Adrafinil, aniracetam, centrophenoxine, deprenyl, desmopressin, modafinil, nicergoline, picamilone, piracetam, pramiracetam, vasopressin, Xan-Pro™

Memory (also see cognitive & senile dementia)

General support: Krill, picamilone, vinpocetine Imprinting (for later recall): Desmopressin, vasopressin Medium-long term: Hydergine, phosphatidylserine Short term: Aniracetam, piracetam, pramiracetam Speed of recall: Centrophenoxine, pyritinol

Methylation (conversion of one chemical into another inside the body)

ATP-Boost™, Beyond B12® Bio-En’R-Gy®, Boluoke®, SAMe, Wobenzym®, Xan-Pro™

Migraines (also see pain relief)

Beyond B12®, nicergoline, memantine, picamilone, Quinton®

Minerals (including trace- also see vitamins)

Beyond Chelation Improved®, Bone-Pro2™, Gamalate®, Quinton®

Mitochondrial support

ATP-Boost™, CoQ10, deprenyl, glutathione, hydergine, idebenone, PQQ, pregnenolone, SAMe

Multiple Sclerosis (also see mitochondrial support) Melatonin, naltrexone, TRH

Nail condition

Gerovital-H3®, krill

Narcolepsy (sleeping in the daytime)

Adrafinil, melatonin, modafinil, picamilone

Nitric Oxide release

Nitric-Pro™, Neo40®, Nitric Oxide saliva test strips

Oral health care (see teeth & gums) Osteoporosis (see bone problems) Pain relief

ATP-Boost™, Gerovital-H3®, memantine, milnacipran, nicergoline, oxytocin, Wobenzym®

Parasites (see infections) Parkinson’s disease (see senile dementia) Peptides

-short chain peptide bioregulators Adrenals = Glandokort®, Bladder = Chitomur® Blood vessels = Ventfort®, Bone marrow = Bonomarlot® Brain (CNS) = Cerluten®, Cartilage = Sigumir® Heart = Chelohart®, Kidney = Pielotak®, Liver = Svetinorm®, Lungs = Taxorest® Muscle = Gotratix®, Ovaries = Zhenoluten® Pancreas = Suprefort®, Parathyroid = Bobothyrk® Pineal = Endoluten®, Prostate = Libidon® Retina = Visoluten®, Stomach = Stamakort® Testes = Testoluten®, Thymus = Vladonix® Thyroid = Thyreogen® -other peptides GHRP2 (GHRP2-Pro™), GHRP6 (Releasing-Pro™) Sermorelin (Serm-Pro™), TRH (Abaris™)

Pets (see Animal use) Photoaging (see radiation & skin problems) Ph balance (rebalancing)

Active H-minus®, Dr. Gordon’s organic greens®, Quinton®

Physical energy improvement (also see mental stimulants)

Active H-minus®, ATP-Boost™, Beyond B12®, CoQ10, idebenone, L-carnosine, maca, PQQ, pregnenolone, SAMe, yohimbine

PMS (pre-menstrual syndrome)

Beyond B12®, krill, HRT Plus®, maca, Peptide Bioregulator - Zhenoluten®, vinpocetine

Premature ejaculation/ ejaculate (also see erectile

dysfunction & sex-libido) Oxytocin

Probiotics

Beyond Fiber®, Digestif®, Dr. Gordon’s organic greens®, Quinton®

Prostate (also see cancer)

Beyond B12™, D3, DIM-Pro2™, dutasteride, finasteride, HRT Plus®, melatonin, Peptide Bioregulators - Chitomur® & Libidon®, Prostate-Pro2™

Prolactin alteration

Bromocriptine, cabergoline, GABOB, Gamalate®

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PSA (prostate specific antigen- see prostate)

Sunburn (see radiation)

Urination (frequent)

Syndrome X (metabolic syndrome)

Peptide Bioregulator -Chitomur®, vasopressin

Radiation (see skin problems)

Aminoguanidine, ATP-Boost™, krill, melatonin, metformin

Tanning (darkening the coloration of skin)

RNA (see DNA support)

MSH

Senile dementia (also see cognitive & memory)

Alzheimer’s: Centrophenoxine, CurcuminSR™, galantamine, hydergine, memantine, nicergoline General support: Anacervix®, aniracetam, piracetam, pramiracetam, vinpocetine, Wobenzym® Parkinson’s: Bromocriptine, cabergoline, deprenyl, rasagiline

Senility

Gerovital-H3®

Sex (libido, also see erectile dysfunction & premature ejaculation)

Andro-Pro™, deprenyl, maca, MSH, oxytocin, yohimbine

Skin problems (also see tanning)

Anti-glycation: Aminoguanidine, L-carnosine Anti-oxidant: Crème-Pro™ Protector Cancer (non-melanoma): BEC5® Curaderm Cellulite: Crème-Pro™ Celluless Collagen: Hy-Col™ Environmental: Crème-Pro™ Protector Fine lines: Crème-Pro™ Smoother General support: Gerovital-H3®, Quinton®, thyroid Hyaluronic acid: Hy-Col™ Infections: Silver protein, Thym-Uvocal® Moisturizer: Crème-Pro™ Moisturizer Radiation: Crème-Pro™ Protector, melatonin Scars/ stretch marks: Tamanu oil Sun spots: BEC5® Curaderm Wounds: HemaGel® Wrinkles: Retin-A®

Sleep disorders

For less sleep: adrafinil, ATP-Boost™, modafinil For more sleep: 5HTP, gabapentin, L-tryptophan, melatonin

Smoking cessation

Teeth & gum disorders

Doxycycline, Gengigel®, NeyDent®, silver protein, Quinton®, zeolite

Telomeres (also see DNA support) Krill, L-carnosine, TA65®

Testosterone & testes (also see fertility and prostate) Andro-Pro™, Anastrozole (Arimidex®), Beyond B12®, Beyond GHS®, DIM-Pro2™, melatonin, oxytocin, Peptide Bioregulator - Testoluten®, TRH

Therapeutic equipment (see at-home therapeutics) Thyroids

Natural brands: Armour®, ERFA®, West® (Nature®) Synthetic brands: IBSA® (T3+T4), Eutirox® (T4), Tiromel® (T3) Supporting agents: Peptide Bioregulator - Thyreogen®

Travel (see frequent fliers) Triglycerides (see blood disorders) Veterinarian (see animal use) Vitamins (also see minerals)

Benfotiamine, Beyond B12®, Beyond Chelation Improved®, Bio- En’R-Gy C®, CoQ10, D3, GABOB, Gamalate®, Nitric Pro™, PQQ, pyridoxamine, Xan-Pro™

Water

Active H-minus®, Quinton®

Weight gain (muscle mass)

Andro-Pro™, Beyond GHS®, GABOB, GHRP6, sermorelin

Weight loss (Appetite suppressants and diet aids)

5HTP

Spine Issues

Peptide Bioregulator- cartilage (Sigumir®), Novisyn®

Sports (see growth hormone, estrogen alteration, physical energy & testosterone) Sublingual products

Beyond B12™, Oxytocin (Oxy-Sub™), Sermorelin (SermPro™)

5HTP, acarbose, aminoguanidine, ATP-Boost™, benfotiamine, Beyond Fiber®, DIM-Pro2™, Dr. Gordon’s organic greens®, galantamine, GHRP2, L-tryptophan, metformin, MSH2, thyroid, TRH, Xan-Pro™

Well-being (also see depression)

Active H-minus®, aniracetam, ATP-Boost™, Beyond B12®, deprenyl, Gamalate®, Gerovital-H3®, krill, melatonin, picamilone, piracetam, pramiracetam, SAMe, thymus, thyroid, Wobenzym®

Stress (also see cortisol)

5HTP, GABOB, Gamalate® , Gerovital-H3®, maca, L-tryptophan, melatonin, oxytocin, picamilone, phenytoin, propranolol, pregnenolone

Stroke

Anacervix®, aniracetam, Boluoke®, hydergine, idebenone, nicergoline, Nitric-Pro™, picamilone, piracetam, PQQ, pramiracetam, pregnenolone, vinpocetine

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