IHR Show 2019

Volume 20 – Issue 4 – 2019

trending

PUBLICATIONS M AIL 42709013 | 920 YONGE ST, SUITE 608 | TORONTO ONTARIO, M4W 3C7 | $6

Metro adopts a new ecoresponsible policy cannabis news

plant based news

Plant Based World Conference 2019

WWW.INTEGRATEDHEALTHHUB.NET

Zenabis now licensed cover story

À Fleur de Vie, Qc SHOW ISSUE 2019

Scent: Soothing atmosphere

Litis™

NPN 80070540

Gastrointestinal Health Formula

✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓

Modulates GI immune system Exhibits anti-inflammatory activity Promotes regeneration of GI mucosa Demonstrates anti-microbial activity Alleviates symptoms of GI distress Soothes inflamed mucous membranes Maintains mucosal cell integrity Helps repair GI tract

Litis™ is an innovative, natural health product developed by Alpha Science™ Laboratories which is designed to support the gastrointestinal (GI) health through supporting the GI mucosal immune system. Litis™ contains spleen-derived bioactive peptides, leukotrienes, platelet-derived growth factors, and cytokines. These ingredients are known to modulate the immune system, promote regrowth of GI mucosa and act as anti-inflammatories. The spleenderived factors in combination with L-glutamine and medicinal herbs support and repair the entire GI tract.

The Litis™ formula contains a specific fraction of spleen extract (Fraction-23®), a research product of Alpha Science™ Laboratories. Fraction-23® is a specific combination of key bioactive isolates which includes tuftsin and splenopentin, platelet-derived growth factors and immune modulators obtained from spleen extract by a proprietary process developed by Alpha Science™ Laboratories. Fraction-23® has been scientifically evaluated for efficacy using an equine model.

The gastrointestinal system plays a key role in the complex mechanisms of immune-regulation as 70% of the entire immune system is found at this level.

Clinically evaluated for efficacy, Fraction-23® has shown to help repair the gastrointestinal mucosa.

Litis™ is indicated for use with gastrointestinal inflammation such as irritable bowels, peptic ulcers, chronic ulcerative colitis, Crohn’s disease and celiac disease. Litis™ helps to stimulate appetite and reduce symptoms of GI distress. Litis™ is well tolerated and has shown no adverse reactions.

Alpha Science™ Litis™ contains (per capsule): Spleen extract (Fraction-23®) ........................................................... 150 mg Licorice Root (Glycyrrhiza glabra) ...................................................... 300 mg L-Glutamine ...................................................................................... 100 mg Marshmallow Root (Althaea officinalis)............................................... 50 mg

Recommended dose: Adults − Take 1 capsule twice per day with food or as directed by your health care practitioner. Take it a few hours before or after taking other medications or natural health products.

Litis™ is manufactured under strict GMP standards and contains no preservatives, dairy, corn, wheat or gluten.

AlphaScienceLabs.com • 1-888-299-0318 • 795 Pharamacy Ave., Toronto, ON M1L 3K2 CANADA

Probiotic Factors™ Probiotic Formula with Psyllium-Free Fibre 60 vegcaps/bottle – UPC 826913607057 NPN 80026706 RECOMMENDED USE: Probiotics contribute to a natural healthy gut flora.

MEDICINAL INGREDIENTS PER 1 CAPSULE: Lactobacillus acidophilus ......................................................1.25 Billion organisms Lactobacillus casei ................................................................1.25 Billion organisms Lactobacillus plantarum .......................................................1.25 Billion organisms Lactobacillus rhamnosus ......................................................1.25 Billion organisms Bifidobacterium bifidum.......................................................1.25 Billion organisms Bifidobacterium breve ..........................................................1.25 Billion organisms Bifidobacterium longum subsp. infantis ...............................1.25 Billion organisms Bifidobacterium longum subsp. longum ...............................1.25 Billion organisms

Ultimate Fibre Plus™

Contains 6 Soluble Fibres, 4 Probiotics & Prebiotic, 2 GI Herbal Support, Bioflavonoid & Detoxification Support 340 g/bottle – UPC 826913606555 | NPN 80034680 180 vegcaps/bottle – UPC 826913606500 | NPN 80034794 RECOMMENDED USES: Source of fibres for the maintenance of good health by acting as a bulk forming laxative. Provides gentle relief of constipation and/or irregularity. Source of probiotics that temporarily modify gut flora.

MEDICINAL INGREDIENTS PER 1 TEASPOON (6 g) [PER 1 CAPSULE]: Plantago ovata (Psyllium Husk & Seed) ..................................... 2500 mg [250 mg] Pyrus malus (Apple Fibre).......................................................... 1320 mg [132 mg] Amorphophallus konjac (Glucomannan Tuber) .......................... 1000 mg [100 mg] Linum usitatissimum (Flax Seed) ................................................... 840 mg [84 mg] Cichorium intybus (Inulin Root/Fructooligosaccharides) ................ 600 mg [60 mg] Cyamopsis tetragonoloba (Guar Gum) ............................................ 600 mg [60 mg] Althaea officinalis (Marshmallow Root)...................................... 456 mg [45.6 mg] Citrus aurantium (Bitter Orange Fruit) [Hesperidin]....................... 150 mg [15 mg] Ulmus rubra (Slippery Elm Stem Inner Bark) .............................. 144 mg [1.44 mg] Bifidobacterium bifidum ADDITIONAL INGREDIENTS: (Whole Cell-HA-132) ................................... 150 Million CFU* [150 Million CFU*] Cichorium intybus (Inulin), Guar gum, Linum usitatissimum (Flaxseed Mucilage), Lactobacillus acidophilus Apple fibre, Hypromellose (vegetarian capsule shell).

(Whole Cell-HA-122) ................................... 150 Million CFU* [150 Million CFU*] Lactobacillus casei (Whole Cell-HA-108)......... 150 Million CFU* [150 Million CFU*] Lactobacillus plantarum (Whole Cell-HA-119) ................................... 150 Million CFU* [150 Million CFU*] RECOMMENDED DOSE: *Colony Forming Units Adults: 1 - 2 capsules once daily.

ADDITIONAL INGREDIENTS: Sunflower lecithin, Stevia, [Hypromellose CONTRAINDICATIONS: (vegetarian capsule shell)].

Do not use if you are experiencing nausea, fever, vomiting, bloody diarrhea or severe abdominal pain. Do not use if you have an immune-compromised condition RECOMMENDED DOSE: (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment). POWDER: Adults: Mix 1 teaspoon (6 g) with at least 315 mL of water or juice one to two time(s) per day with food and at least 2-3 hours before or after taking antibiotics or other medications. Stir briskly and drink immediately. Avoid taking STORAGE: immediately before bedtime. Maintain adequate fluid intake. Taking this product Do not refrigerate. Store protected from light and moisture. with insufficient liquid may result in choking and/or esophageal blockage/ obstruction of the throat, esophagus or intestine. Effects observed 12-14 hours ALLERGENS: after first dose, and may take 2-3 days.

Contains no corn, dairy, yeast, soy, wheat or gluten. Compatible for a vegan diet.

CAPSULES: Adults: Take 5 capsules twice per day with food and at least 2-3 hours before or after taking antibiotics or other medications. Avoid taking immediately before bedtime. Maintain adequate fluid intake. Taking this product with insufficient liquid may result in choking and/or esophageal blockage/obstruction of the throat, esophagus or intestine. Effects observed 12-14 hours after first dose, and may take 2-3 days. ►Helps to manage and reduce the risk of acute diarrhea STORAGE: Do not refrigerate. Store away from ►Inhibits the adhesion of enteropathogenic bacteria children and protected from light and moisture. ►Enhances the bioavailability and uptake of minerals ALLERGENS: Contains no corn, dairy, gluten, soy, wheat or yeast. However, this product may have ►Lowers some risk factors for cardiovascular disease come into contact with milk and/or soy. Do not use ►May reduce symptoms associated with IBS this product if you have a milk and/or soy allergy. ►Improves the microbial balance of the gut ►Stimulates colonic microbial growth ►Promotes satiety and weight loss

►Reduces serum cholesterol levels ►Stimulates immune system reactivity ►Provides both soluble (fruit pectin) and insoluble fibre (flax), no psyllium

►Maintains healthy cholesterol levels ►Aids in achieving healthy weight ►Helps control blood sugar levels ►Acts as a bulk forming laxative

AlphaScienceLabs.com • 1-888-299-0318 • 795 Pharamacy Ave., Toronto, ON M1L 3K2 CANADA

A breakthrough for your health, backed by leading scientists.

Is a unique form of vitamin B3 shown to maintain NAD levels.

NAD is found in every living cell, and fuels the mitochondria, which keeps almost every tissue in the body healthy.

Humans lose up to 50% of our NAD levels between the ages of 40 and 60 and TRU NIAGENTM helps with encouraging cellular health.

Support Energy Metabolism

Support Biological Functions

Help Encourage Cellular Health

Visit us at Booth #1645 to learn how to share in the success of Tru Niagen.

www.clmhealth.com Contact us: 877-263-7330

CONTENTS rotein

p n a e l c o t t e Your secr

r protein ba n a le c d e Stripp e. hing to hidLETTER UTEN with notPUBLISER’S GL REE Traffic isn’t so bad when it makes you Money F EDITORIAL BOARD Our contributors in this issue

GET THE GOOD Check out this market’s news

10 11

12 14 16

24

PLANT BASED NEWS Plant Based World Conference 2019

0 calories

than 14 TOP Less SELLER in te ro Australia High in p Do you know ade 3inones?

Mthis

re gredients High in fib No GMO in nts ral ingredie TRENDING Low carb 100% natu dly Keto frien Sobeys, Walmart and Metro

ecrets.co www.slims

CANNABIS BUSINESS USE Medical Marijuana

36 40

STUDY Curcumin BioBDMC30™

20 45

WANT TO SEE MORE? FOR EXTRA CONTENT DOWNLOAD INTEGRATED HEALTH’S DIGITAL VERSION FROM ITUNES OR GOOGLE PLAY

COVER STORY À Fleur de Vie

CONTINUING EDUCATION The Keto diet

IT’S NEW. IT’S POWERFUL. IT’S THE NEXT GENERATION.

Introducing PURICA Recovery 3.0.

For rapid inflammation relief & healing We’ve combined the best of PURICA Recovery with the rapid relief of PURICA Curcumin. The result is PURICA Recovery 3.0. • It’s a powerful antioxidant, anti-inflammatory and immunity optimizer • Supports joint health and proper muscle function • Helps reduce symptoms of stress such as fatigue, sleeplessness, irritability and inability to concentrate.

PURICA Recovery 3.0: For athletes and active living people wanting to perform at the top of their game.

purica.com

‫נס״ ד‬ PUBLISHER’S LETTER

ISSN 1197 - 1495 | VOLUME 20 ISSUE 4

TRAFFIC ISN’T SO BAD WHEN IT MAKES YOU MONEY

FOUNDER & THOUGHTSMITH

Olivier Felicio CONTENT CREATOR

Andrew Miller ART DIRECTOR

Marcelo Ramos

G

etting people to visit your website isn’t easy, it also isn’t cheap.

The bottom line is simple, clicks cost money. Unique visitors, impressions, social media influencers, all of those cost money.

Of course, there are numerous ways to get more out of your online advertising budget, but if you want to be certain you’re always driving a return on your investments, there are some fundamentals to turn more site visitors into customers:

WEB GURU

Karl Delgadillo MARKETING COORDINATOR

Matias Redondo CONTRIBUTORS

Denis Courchesne, Daniel Dereser, Franco Cavalari, David Foreman, Mike Hannalah and Lewis Retik.

Pop-ups over the years have not got the best rap, but with the right message and timing, Pop-ups can be an amazing tool for pulling in site traffic. Thus turning their interests into relevant and continuous engagement.

Conversion rate optimization. It’s the practice of improving the conversion rate of your advertising efforts by increasing the likelihood of visitors taking a certain action that brings them closer to becoming a customer. CRO (or at least elements of it) is sometimes also referred to as marketing optimization, website optimization, landing page optimization (LPO), growth hacking, optimization and testing, customer experience (CX), usability (UX) or marketing experimentation.

Olivier Felicio

Publisher/Editor-in-Chief

PRESIDENT

Olivier Felicio

SUBSCRIPTION RATES Canada $50 (gst included) for nine issues (one year) USA $60 CHANGE OF ADDRESS email: circulation@thergmgroup.net telephone: 416-203-7900 fax: 416-703-6392 or send your cover label and new address to Integrated Health c/o IHR Magazine 920 Yonge Street, Suite 608 Toronto, ON Canada M4W 3C7

ADVERTISING INFORMATION PUBLISHER

❱ FIND US ON

OLIVIER FELICIO – Toronto Office tel: 416.203.7900 x 6107 / email: olivier@thergmgroup.net 608, 920 Yonge Street, Toronto, ON M4W 3C7

10 / THE HUB - IHR / SHOW ISSUE 2019

SUCCESS SPECIALIST JUSTIN BARONE – Toronto Office tel: 416.203.7900 x 6120 / email: justin@thergmgroup.net 608, 920 Yonge Street, Toronto, ON M4W 3C7 Published by Rive Gauche Media Inc. Canada Post Canadian Publications Mail 42709013 The publisher does not assume any responsibility for the contents of any advertisement and any and all representations or warranties made in such advertising are those of the advertiser and not of the publisher. The publisher is not liable to any advertiser for any misprints in advertising not the fault of the publisher and in such an event the limit of the publisher’s liability shall not exceed the amount of the publisher’s charge for such advertising. No portion of this publication may be reproduced, in all or part, without the express written permission of the publisher. All rights reserved. ©Copyright 2018 Rive Gauche Media Inc. ihr magazine is pleased to review unsolicited submissions for editorial consideration under the following conditions: all material submitted for editorial consideration (photographs, illustrations, written text in electronic or hard copy format) may be used by ihr Media Inc. and their affiliates for editorial purposes in any media (whether printed, electronic, internet, disc, etc.) without the consent of, or the payment of compensation to, the party providing such material. Please direct submissions to the Editor, ihr magazine.

GENERAL CUSTOMER CARE MANAGER LUCY HOLDEN – Montreal Office General Customer Care Manager tel: 514.381.5196 / lucy@thergmgroup.net 412E, 1255 Phillips Square, Montreal, QC H3B 3G1

INTERNATIONAL SALES INQUIRIES MEHER VESAVEVALA tel: +91 9821136069 / mehernavaz@hotmail.com PURVAZE BUXY tel: +91 9820129492 / purvaze@gmail.com

EITORIAL BOARD

EDITORIAL BOARD

DENIS COURCHESNE

DANIEL DERESER

FRANCO CAVALARI

Denis Courchesne has a solid background in sales and marketing working for companies such as Mosaic, Evian, Cadbury Adams, Bioforce Canada and Purity Life Health Products. He is president of Quebec Contact Inc., a consultancy firm dedicated to helping clients successfully develop and grow business in the Quebec market. After evolving and advancing his knowledge working in the natural product industry for over 17 years, Denis shares his experience and observations of the trade in Quebec with our readers.

Daniel Dereser, a Doctor of Pharmacy in France, received his degree from Université Aix-Marseille II in 2003 and a training certificate in clinical homeopathy for pharmacists through the Center for Education and Development of Homeopathy (CEDH). Before becoming the CEO of Boiron Canada in 2015, Dereser held the position of director of medical development for Boiron Canada and Boiron U.S.A. He also serves on the board of directors of the Canadian Homeopathic Pharmaceutical Association (CHPA).

Franco Cavaleri completed his BSc with a major in Human Nutrition from the University of British Columbia. He is currently in the last phase of postgraduate doctoral study (current status PhD candidate) at the Faculty of Medicine’s Experimental Medicine Program. Research interest and focus on nutraceutical pharmacology in the context of the pathology of inflammation and inflammatory disease Faculty of Medicine’s Experimental Medicine Program.

DAVID FOREMAN

MIKE HANNALAH

LEWIS RETIK

David Foreman RPh, is a pharmacist, author and media personality known to consumers nationwide as, “The Herbal Pharmacist.”

Foreman is a graduate of the University of South Carolina College of Pharmacy, currently serves on Organic & Natural Health Association’s Scientific Advisory Board, and is author of 4 Pillars of Health: Heart Disease.

With experience in both the professional and regulatory sectors of pharmacy, Mike Hannalah holds a comprehensive knowledge and understanding of the unique needs, challenges and opportunities of pharmacists in Ontario. Currently, he is the director of Smith’s Pharmacy in Toronto, and is a council member of District M at the Ontario College of Pharmacists.

Lewis Retik is the leader of the Advertising & Product Regulatory group and co-leader of the Food & Beverage group at Gowling WLG. As a partner in Gowling WLG’s Ottawa office, he practices primarily in the area of regulatory and commercial law. Lewis’ practice focuses on regulated products, including product distribution, manufacturing, advertising, packaging and labelling, and regulatory licensing.

11 / THE HUB - IHR / SHOW ISSUE 2019

The purpose of our editorial board is to help guide the direction of the publication in a manner that a) improves its quality and rigor, b) exerts a positive impact on patient outcomes, c) contributes to knowledge of integrative health-care, and d) showcases evolving trends in the health-care industry. We believe that our unique blend of readers dictate the tone of our magazine, which allows us to provide you with the most accurate, up-to-date, and essential information relevant to your business. Our editorial committee is comprised of thought provokers who have shaped the industry and whose experience is vital in providing you with the tools to succeed.

GET THE GOODS

GET

THESE GOODS FREE

THE FIRST 100 RETAILERS TO FAX AT 416-703-6392 WILL GET THESE GOODS FOR FREE

Slim Secrets Keto Friendly Bare Bar These Low Sugar, Low Calorie, Keto friendly bars have been all the rage in Australia for over 10 years and are picking up some serious steam in North America with weight conscientious men and women looking for a healthy and low calorie snack alternative. They have been endorsed by the likes of Avril Lavigne, World Champion Tennis player Angelique Kerber and Best Selling author Andi Lew. These bars are a fan favourite due to their low calorie count (under 150 calories for all snacks and bars) very low sugars and decadent taste. They are also Celiac friendly, gluten free, and great for people with wheat intolerances and diabetes.

Freedom bar All the bars are GLUTEN FREE, DAIRY FREE, SOY FREE, NON-GMO, VEGAN, NO ADDED SUGAR and KOSHER. They each have as little as 4-6 ingredients all of which we all know and recognize. What’s great about Freedom Bar is how ‘freeing’ they are for everyone. The bars have been adapted to not only fit those with strict dietary needs but in addition. Not much option like these bars for your store(s).

The sweet fling that everyone can have!

NO ADDED SUGAR

Slim Secrets Choc Love Bites by Sophie Monk Developed by a health and wellness coach, these best sellers fly off the shelves as they are a unique chocolate lovers alternative; giving health conscientious customers a guilt free chocolate fix while packing a protein punch. The Love Bites are extremely low in sugars (0.4g) have added protein and come in delicious Dark Chocolate Mint, Protein Milk Chocolate with Caramel Crisps and Protein Milk Chocolate with Crushed Almonds. These are low in carbs, gluten free, suitable for diabetic and come in portion controlled 36g bags.

12 / THE HUB - IHR / SHOW ISSUE 2019

Low carb Gluten free Keto friendly

150 calories and less Made in Australia Portion controlled packs

GET ME THESE GOODS! FILL OUT THE FORM BELLOW CLEARLY AND COMPLETELY.

www.slimsecrets.co

Name

Phone

Store

Fax

Address

E-mail

City

Postal Code

FALL 2016 / VIVAMAGONLINE.COM

59

TOP SELLER

LAKOTA JOINT CARE ARTHROFORMULE Lakota’s bestselling joint pain reliever. Uses the strongest herbal extracts from around the world. Potent varieties of White Willow Bark and Devil’s Claw and much more. Also includes the medicinal mineral Lumanite, which helps rebuild joints. It targets frequent and severe joint pain, providing you with increased flexibility and mobility.

SLIM SECRETS KETO FRIENDLY BARE BAR Let Slim Secrets be your secret weapon for managing your cravings and snacking dilemmas! Double Choc Bare Bars are keto friendly, gluten free, have natural ingredients, high protein, fiber, low carb, low sugar AND best of all taste great! Also available in Berries & Cream and Salted Caramel & Banana varieties. www.slimsecrets.co

ASL SINEWGEN™ 14 / THE HUB - IHR / SHOW ISSUE 2019

JUST WHAT THE WHOLE BODY NEEDS. Alpha Science™ Laboratories has a multi-nutrient formulation were its primary action is to nourish and regenerate tissues stressed by strains, injuries, diseases, as well as to support normal body functions; specifically the muscles, cartilages, ligaments, tendons and cell tissues. It will help reduce acute and chronic pain and inflammation, and it stimulates regeneration and repair. The ingredients in SinewGen™ are expertly formulated to work synergistically to strengthen and repair tissues that are damaged or stressed during athletic or strenuous physical activities. The formulation will help nourish imbalances of the glandular pathways, thus helping with fatigue and mental exhaustion.

Available in 250g and 500g sizes. AlphaScienceLabs.com, 1-888-299-0318

TOP SELLER

Quench-FX™

Alpha Science’s Quench-FX™ contains (per 1 capsule): Camellia sinensis (Green Tea Extract) (95% Polyphenols) .....................................................50 mg Citrus aurantium (Hesperidin) .......................................25 mg Counteracts oxidative stress Curcuma longa (Turmeric Extract) (95% Curcumin) .......15 mg An effective anti-inflammatory for organ systems as R-alpha-Lipoic acid .......................................................50 mg all antioxidants are anti-inflammatory Lycopersicon esculentum (Tomato Extract) Protects tissue and organs from free radicals (5% Lycopene)............................................................10 mg Supports cardiovascular pathways Pine Bark Extract (95% Proanthocyanidins) ..................50 mg Protects macula tissue Sophora japonica (Quercetin) ........................................50 mg Protects the testes, ovaries and prostate Tagetes erecta (Lutein)...................................................10 mg Supports immune and joint health Vaccinium myrtillus (Bilberry Extract)............................25 mg Provides antioxidants for optimal health Vitis vinifera (Grape Seed Extract) Protects the skin (95% Proanthocyanidins) .........................................100 mg Improves insulin sensitivity and glucose tolerance Vitis vinifera (Red Wine Extract) (50% Polyphenols) ......50 mg

✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓

Quench-FX™ contains 11 different antioxidants sequestered in and thus protects the body’s main organ systems. It is effective against all free radicals (oxygen derived, nitrogen derived, single element e.g. Cl2).

AlphaScienceLabs.com • 1-888-299-0318 • 795 Pharamacy Ave., Toronto, ON M1L 3K2 CANADA

15 / THE HUB - IHR / SHOW ISSUE 2019

NPN 80031616 Multi-Organ Protection

TRENDING

Sobeys says Voilà to online grocery delivery

Through its partnership with U.K. e-grocer Ocado Group plc, Sobeys Inc. plans to launch an online grocery delivery service called Voilà next year and build a second automated warehouse for fulfillment.

We are building the most advanced e-commerce infrastructure in Canada.

Parent Empire Company Ltd. said Thursday that the retailer’s initial home delivery offering, Voilà by Sobeys, is slated to get under way in the greater Toronto area and Ottawa in spring 2020 when its previously announced customer fulfillment center (CFC) in Vaughan, Ontario, begins operation.

16 / THE HUB - IHR / SHOW ISSUE 2019

Due to launch in 2021 is Voilà par IGA, an online grocery delivery service for major cities in Quebec that will be served by a second CFC to be built in Pointe-Claire, Montreal.

The Sobeys and IGA Voilà services and the Vaughan and Montreal CFCs will be powered

by Ocado’s Smart online grocery platform.

Sobeys and Ocado announced their partnership in January 2018. Plans call for the development of an e-commerce infrastructure enabling online grocery ordering, automated fulfillment and home delivery. That includes front-end website functionality and mobile ordering; automated warehouses using Ocado’s grid and robots; last-mile routing management technology for delivery trucks; and customer service tools. The Voilà service will offer a selection of up to 39,000 products, including fresh produce, at prices comparable to those at Sobeys and IGA stores, Stellarton,

Nova Scotia-based Empire said. The online grocery brand will carry the tagline “Your groceries delivered. Just like that.”

“We are building the most advanced e-commerce infrastructure in Canada,” Sarah Joyce, senior vice president of e-commerce for Empire, said in a statement. “An online grocery home delivery experience like Voilà

by Sobeys does not yet exist in Canada. While most players in the industry are focused on store pick models to fulfill their online orders, we are building automated warehouses specifically designed for best-in-class home delivery based on a highly successful model from the U.K. Voilà by Sobeys will deliver Canadians exactly what they want, when they want it, every time.”

IGA has provided online grocery pickup and delivery in Quebec for more than 20 years via its IGA.net service. Empire said IGA.net will continue to offer online grocery service in Quebec until Voilà par IGA and the Montreal CFC launch in 2021. Thereafter, IGA.net will continue to serve customers outside the Voilà delivery area.

The Voilà service will offer a selection of up to 39,000 products.

“We’re thrilled to build on our solid legacy of e-commerce in Quebec,” Joyce added.

“When selecting future locations, we consider size of market, population density and potential for growth. Launching in Quebec is another exciting step forward to bringing the world’s most innovative e-commerce solution to Canadians.”

Construction of the Vaughan CFC is on schedule and will cost an estimated $95 million, Empire reported. The company said it expects the Montreal CFC’s construction cost to be about the same or possibly less than Vaughan’s, since the latter facility enables efficiencies in Montreal. Empire plans to partner with its Crombie REIT subsidiary to develop the Montreal CFC and then lease the facility from Crombie.

Empire added that most of the Montreal investment will be incurred by Crombie, while software, licensing and systems integration costs incurred in fiscal 2019 will apply to both CFCs. The company said its e-commerce expansion will create about 1,500 jobs in the greater Toronto and Montreal areas.

Overall, Sobeys owns, affiliates or franchises more than 1,500 stores in all 10 provinces under such banners as Sobeys, Safeway, IGA, Foodland, FreshCo, Thrifty Foods, Farm Boy and Lawtons Drugs. Its retail network also includes 350-plus fuel locations.

TRENDING

Metro adopts a new eco-responsible policy

• Reduce the use of packaging and printed materials; • Implement optimal design; • Select eco-responsible materials; • Facilitate recovery and recycling.

“This new policy is the result of rigorous teamwork and is part of our approach to continuously improve our practices. We know that there is a growing interest in packaging—and plastic in particular—among many groups, including our customers. We are confident that the measures we are putting forward will responsibly and effectively address these challenges,” said Eric La Flèche, President and Chief Executive Officer, METRO.

COMMITMENTS AND ACTIONS In addition to implementing the policy’s principles, METRO is committed to taking action in priority areas owing to their environmental impacts and volumes: • Reduce the number of single-use plastic shopping bags by 50% in METRO’s food and pharmacy banners by the end of the 2023 fiscal year; • Reduce overpackaging and single-use plastics in our food stores’ fresh sections; • Reduce the total weight of the paper

used in the flyers for METRO’s food and pharmacy banners by 10% by the end of the 2022 fiscal year; • For our private brand food packaging, by the end of the fiscal year 2025: - ensure that 100% of the packaging is entirely recyclable or compostable (fibres only) - ensure that 100% of the packaging includes sorting instructions - increase the proportion of postconsumer materials to 45% • Eliminate single-use plastic water bottles used by our employees in METRO’s administrative offices and distribution centres by the end of the 2019 fiscal year.

To consult the Packaging and Printed Materials Management Policy and the full list of commitments, visit metro.ca/responsibility.

In selecting and designing more environmentally friendly packaging and innovating in its business processes, METRO will never compromise on the packaging properties that ensure product preservation, quality and safety.

METRO’s network is also taking other concrete actions. For example, since April 22, customers in Metro stores across Québec can now bring their own reusable containers to purchase fresh products—an initiative that enables METRO to reduce single-use packaging together with its customers.

The important collaboration of customers METRO’s network of food stores and pharmacies is among the largest in Canada and serves millions of customers week after week. The scope of our activities places us in a unique position to receive feedback from customers and raise their awareness of packaging-related issues. “Our approach to managing packaging and printed materials has always rested on best practices and the collaboration between our teams and suppliers. With this new policy, we remain committed to ongoing improvement and innovation and are reaching out to our customers to join us in this major program,”

declared Marie-Claude Bacon, Vice President, Public Affairs and Communications.

It is worth noting that, in addition to the private brand packaging optimization initiatives launched nearly a decade ago, METRO was the very first Canadian food retailer to introduce reusable grocery bags in 2006. The Packaging and Printed Materials Management Policy is in line with METRO’s corporate responsibility approach, which notably aims to adopt responsible procurement practices and manage the company’s environmental footprint.

ABOUT METRO With annual sales of approximately $16 billion, METRO INC. is a food and pharmacy leader in Québec and Ontario. As a retailer, franchisor, distributor, and manufacturer, the company operates or services a network of more than 600 food stores under several banners including Metro, Metro Plus, Super C and Food Basics, as well as of more than 650 drugstores primarily under the Jean Coutu, Brunet, Metro Pharmacy and Drug Basics banners, providing employment to almost 90,000 people. For more details, visit corpo.metro.ca.

17 / THE HUB - IHR / SHOW ISSUE 2019

METRO announced the adoption of its Packaging and Printed Materials Management Policy covering its corporate, food and pharmacy activities. Building on the range of initiatives undertaken over the years, METRO is releasing out a framework to guide its teams and suppliers in the efficient management of its packaging and printed materials, including reduction and optimization. This major program will enable METRO to implement practices to reduce the use of resources, limit product losses and reduce waste generation while contributing to the global movement to tackle single-use plastics. Rooted in two established concepts, life cycle approach and circular economy, the Policy is based on the following four principles:

TRENDING

Walmart Canada Unveils New, State-of-the-Art, “Urban Supercentre Concept”

Walmart has chosen its Toronto-Stockyards location to bring new “Fast Lane” checkout technology to the store and to fully integrate the My Walmart app to allow customers to scan their own products as they shop. Store associates – including new full- and part-time associates – work alongside state-of-the-art technology to help make shopping as easy and convenient as possible for customers. A second Supercentre Concept will launch in Thornhill next year and best practices will be used in future store renovations.

18 / THE HUB - IHR / SHOW ISSUE 2019

New associate positions have been added to focus on customer service, including online grocery and general merchandise pickup. New prototype introduces “Fast Lane”, which allows

customers to use the My Walmart app on their mobile device to shop and check out quickly and seamlessly. New licensee strategy reflects emerging trends and evolving customer needs, adding new partners like Freshii, MINISO, The UPS Store and The Party Shop.

“With our new Urban Supercentre Concept, we’re continuing to position ourselves as a leader in-store design and retail innovation,” said Lee Tappenden, president and CEO of Walmart Canada. “We’re introducing new partners, testing new and innovative technologies, integrating eCommerce with bricks-and-mortar and updating our assortment to improve the customer shopping experience and to appeal more to young families in urban markets.” With the new Urban Supercentre Concept, Walmart Canada is adding technology and convenience for customers, without compromising on the unbeatable low prices and quality Canadians expect from Walmart.

“Our new concept is a symbol of what’s to come in retail and demonstrates our vision for helping Canadians save money and live better, now and in the future,” added Tappenden.

Alpha Science™ Laboratories has a multi-nutrient formulation were its primary action is to nourish and regenerate tissues stressed by strains, injuries, diseases, as well as to support normal body functions; specifically the muscles, cartilages, ligaments, tendons and cell tissues. It will help reduce acute and chronic pain and inflammation, and it stimulates regeneration and repair. The ingredients in SinewGen™ are expertly formulated to work synergistically to strengthen and repair tissues that are damaged or stressed during athletic or strenuous physical activities. The formulation will help nourish imbalances of the glandular pathways, thus helping with fatigue and mental exhaustion.

Available in 250g and 500g sizes. AlphaScienceLabs.com, 1-888-299-0318

What does the new Urban Supercentre Concept look like?

My Walmart App: Customers can expect an easy, fast, and fun shopping experience that allows them to scan items and download digital coupons on the go and store-specific deals for additional savings. The store also offers free Wi-Fi and phone chargers.

Life in the Fast Lane: When My Walmart App users are ready to check out, they enter the “Fast Lane”, scan the barcode on their order, have the order charged to their credit card on file and show the receipt on their phone to the “Fast Lane” associate.

Associates have received additional training to help customers use the Fast Lane smoothly. Third-Party Licensees: New concept stores will offer customers an array of new and exciting licensee concepts based on Walmart’s evolving licensee strategy. At the Stockyards Walmart, licensee partnerships include Freshii, the Party Shop, The UPS store, MINISO, Naoki Sushi and a newly renovated McDonald’s. These licensees reflect current and emerging trends and aim to make our customers’ lives easier while offering an enhanced shopping experience.

Omni Store: The Stockyards Walmart has a dedicated Walmart.ca section, where customers can see and shop for extended aisle products and speak with expert associates who can answer questions and assist with online orders. This area will also be used to host pop-up shops for online vendors. The new prototype also features expanded and

TRENDING

improved pickup areas for added customer convenience both inside and outside the store. Community Hub: The Stockyards Store features a seating section where customers can eat meals, sit down with friends and family and check out a community board featuring local news, activities and events.

Fresh Market: The grocery section has been renamed Fresh Market and carries top quality fruits and vegetables, including organics as well as 100% Canadian beef, chicken, pork and seafood. The grocery department has been redesigned to include more theatre lighting and wood panel wall treatment for a market look and feel. Family-Friendly: The new store features two dedicated nursing rooms, a redesigned toy section and the company’s largest and only full-service Party Shop.

Cleaner, Brighter and Enhanced Design and Layout: Several innovations from previous Walmart Canada prototypes will be integrated into the Urban Supercentre Concept, including improvements to product displays, signage and floor plans. Associate Space:

The associate lounge has been updated to include sofas for lounging, bar top tables, and charging stations.

WALMART CANADA INVESTMENT IN BRICKS AND MORTAR Last month, the company announced an investment of $200 million in its store network, with a focus on refurbishing and refreshing 31 stores. Over the last five years, the company has invested over $1 billion in its Canadian store network.

About Walmart Stockyards • 300 full- and part-time Associates; • Approximately 139,000 square feet; • First opened in January 2005; • One of 135 Supercentres in Ontario; • First Urban Supercentre Concept in the country.

CANNABIS BUSINESS USE

20 / THE HUB - IHR / SHOW ISSUE 2019

MEDICAL MARIJUANA DOES NOT LOWER OPIOID OVERDOSE DEATH RATES, STUDY FINDS Some thought people with opioid addiction would turn to medical marijuana instead. It seems they were wrong.

Legalizing medical marijuana does not lower the rate of deadly opioid overdoses, according to a study released Monday.

The findings, published in the journal Proceedings of the National Academy of Sciences, may serve as a blow to those in the cannabis industry, and even doctors, who hoped that laws in favor of medical

marijuana might bring down the ever-rising rates of people dying from overdosing on heroin or other opioids. The intriguing promise of legal medical cannabis lowering opioid overdose rates was based in part on a 2014 study that showed that states that had passed medical marijuana laws by 2010 had about a 25 percent lower opioid overdose death rate than states that did not allow medical marijuana. “It would be wonderful if it worked, but it doesn’t seem like it does,” said the new study’s lead author, Chelsea

Shover, apostdoctoral research fellow at Stanford University.

About 47,600 people died in the U.S. of an opioid overdose in 2017, according to data from the Centers for Disease Control and Prevention. That’s more than 130 people a day.

“A lot of people treated it as evidence that medical cannabis could reverse the opioid crisis,” Shover said of the 2014 study. “But does that really hold up over time? In short, what we found was no.”

CANNABIS BUSINESS USE

Indeed, even authors of that 2014 paper expressed caution at the time, writing, “Although the present study provides evidence that medical cannabis laws are associated with reductions in opioid analgesic overdose mortality on a population level, proposed mechanisms for this association are speculative and rely on indirect evidence.”

So Shover and her colleagues replicated the original study, but with expanded data to look at states that legalized medical marijuana through 2017. While they did confirm the preliminary 2014 finding, the results changed as the years went by and additional states passed medical cannabis laws.

“What we found was that association between enacting a medical cannabis law and the rate of deaths from opioid overdose actually reversed over time,” Shover said. “When we did the study in 2017, the association was that states that enacted a medical cannabis law actually had higher opioid overdose deaths after the laws took effect.” Those states, they found, had about a 23 percent higher opioid overdose death rate than states in which medical marijuana remained illegal.

“With the benefit of the passage of time and more data, the scientific community has a clearer view,” she added. Experts not involved in the new research agreed. “We really have to proceed cautiously when we look at state-level findings to support or dispute the potential role that cannabis might have within the space of the opioid epidemic. You cannot come to any causal conclusion,” said Ziva Cooper, research director at theUCLA Cannabis Research Initiative

“We don’t think cannabis was saving lives at the population level 10 years ago, and we don’t think it’s killing people now,” Shover said. “We think these two factors are separate issues.” The study’s authors stressed, however, that their findings should not derail research into the possible benefits of medicinal marijuana, even as it relates to the opioid epidemic. In fact, a recent study from the Icahn School of Medicine at Mount Sinai found that a component of cannabis called cannabidiol (CBD) could reduce cravings and anxiety in people with a history of heroin abuse.

FDA TAKING FIRST STEPS TOWARD REGULATION OF CBD PRODUCTS “We don’t know what else will be found regarding medical marijuana. That research should absolutely continue,” Shover said.

But, she adds, lawmakers should not assume medical marijuana is an effective strategy for addressing the opioid crisis.

Pot’s popularity — either for recreational or medicinal use — shows no sign of waning.

And much of it is driven by older adults hoping cannabis will ease a variety of ailments. A recent University of Colorado study found adults over age 65 generally use pot to treat pain, anxiety and depression.

Indeed, data from the National Survey on Drug Use and Health show a more than tenfold increase in marijuana use among baby boomers since 2007. Currently, 33 states have comprehensive medical marijuana laws, while 11 states and the District of Columbia also have laws allowing recreational marijuana.

21 / THE HUB - IHR / SHOW ISSUE 2019

A lot of people treated it as evidence that medical cannabis could reverse the opioid crisis.

at the Jane and Terry Semel Institute for Neuroscience and Human Behavior. “These are correlations based on a lot of things that are happening in these individual states,” Cooper said. Indeed, Shover proposed a different explanation for the original 2014 finding.

States that had passed the earliest laws legalizing medical marijuana (Alaska, California, Colorado, Oregon and Washington) tended to be wealthier. And they may have had more access to addiction treatment and medications used to reverse opioid overdoses.

CANNABIS BUSINESS USE

CANNABIS OIL

Zenabis expects to have its initial cannabis oil products available for sale in both the medical and adult use markets by early Q2, 2019 and will be launching additional formats and formulations throughout the year. “This approval provides us with the ability to serve new and existing customers with an expanded range of adult use and medical products through new and easy to use consumption methods. This product category is incredibly important for Zenabis, as it supports our overall growth and product leadership strategy,” said Andrew Grieve, Chief Executive Officer of Zenabis.

“Ingestion of cannabis oil tends to offer a longer lasting effect than vaping or smoking dried cannabis, providing medical clients and adult use consumers with a broader set of options in Zenabis products.

We look forward to bringing our cannabis oil products to market and continuing to innovate and expand our product offerings.

In addition, with this update to our Atholville processing license, we now have the capacity

methods to ensure the highest quality of consumer products. Zenabis values quality first and, as with all Zenabis products, our cannabis oil is tested by an independent third-party lab to ensure product safety, consistency and quality.

to develop a variety of additional value-added cannabis oil products, and cannabis extract products consistent with the proposed amendments to the Cannabis Regulations that allow for greater product diversity.”

CANNABIS OIL: A VALUE-ADDED PRODUCT OPPORTUNITY Cannabis oil is a value-added option for both medical clients and adult use cannabis consumers. Cannabis oil products may be sold as oral drops or sprays, or in soft gel capsules, providing consumers a convenient, controlled and discrete dose. Cannabis oil tends to have longer lasting effects when compared to vaporizing or smoking dried cannabis. Zenabis cannabis oil products are manufactured from high-grade plant material using highly engineered extraction

ZENABIS ATHOLVILLE LICENSE AMENDMENT AND CONSTRUCTION UPDATE Zenabis is pleased to announce that it has received license amendment approval from Health Canada for three additional flower rooms at its Zenabis Atholville facility. This represents an additional 2,100kg of annual production capacity and 10,500 sq. ft. of incremental licensed operational space. With this amendment, the combined licensed annual production capacity of Zenabis Atholville, Zenabis Stellarton, and Zenabis Delta is now 10,200kg.

Construction at Zenabis Atholville remains on budget and on schedule, with ongoing conversion work expected to add an additional 25,000kg in annual production capacity that will become operational in stages over the course of Q2 2019.

EMPLOYEE COUNT SURPASSES 600 Zenabis’ employee count continues to grow in line with its operational footprint, largely driven by several recent license approvals from Health Canada, including the standard cultivation license granted to our facility in Stellarton, NS, and today’s announcements on the approval to process and sell cannabis oil products and the expansion of our operational space in Atholville, NB. The number of Zenabis’ employees, including contractors and seasonal workers, now exceeds 600, have been fewer than 400 as of December 1st, 2018.

Neither TSX Venture Exchange nor it’s Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

23 / THE HUB - IHR / SHOW ISSUE 2019

Zenabis Global Inc. (“Zenabis”) (TSXV: ZENA) announced today that it is now licensed to process and sell cannabis oil products in Canada. The license enables Zenabis to now sell cannabis oil produced at its Atholville, New Brunswick facility, one of the largest indoor cannabis growing facilities in Canada, where Zenabis was already processing oil.

Zenabis expects to market and sell cannabis oil products to its medical clients and to adult use consumers through supply and distribution agreements that Zenabis has in place with nine Canadian jurisdictions including British Columbia, Alberta, Saskatchewan, Quebec, Nova Scotia, New Brunswick, Manitoba, Prince Edward Island, and the Yukon.

PLANT BASED NEWS

Plant Based

World 24 / THE HUB - IHR / SHOW ISSUE 2019

Conference 2019

PLANT BASED NEWS

PBW is the only event that provides a professional space where plant-based product manufacturers, food service providers, retailers, entrepreneurs, investors, healthcare professionals and consumers alike can receive world-class education, high level networking opportunities and the most up to date innovations in plant-based living.

25 / THE HUB - IHR / SHOW ISSUE 2019

Official Event from the Plant Based World Conference 2019 in NYC

PLANT BASED NEWS

The Javits Center was the place to be for anyone and everyone interested in learning about the growth of the plant-based foods market, which is transforming the way people eat.

26 / THE HUB - IHR / SHOW ISSUE 2019

Trade show management company JD Events announced that 3,737 attendees participated in the launch of the Plant-Based World Conference & Expo. The event was supported by founding partners Plant-Based Foods Association, Eat for the Planet, The Plantrician Project, and Follow Your Heart.

“We had attendees who travelled from all 50 states and countries throughout the world to be a part of this first-of-its-kind event. A healthcare conference, a business conference, an expo open to the general public all rolled into one epic gathering of humans with the common belief that what we eat, how we feel and the world we share are all integrally connected,” said Ben Davis, Content & Communications Director, Plant-Based World Conference & Expo. “We received positive feedback from exhibitors on the quality of the attendees they met and from attendees on the content in three education tracks and the general keynote presentations. We thank our exhibitors, sponsors, speakers, attendees, media partners, supporting organizations and partners who helped to make this launch event a huge success.”

The expo hall was packed with professionals and consumers who tasted and sourced plant-based products from 125 exhibitors and sponsors. Delicious and innovative plantbased foods solutions were offered, including: chef-created, plant-based seafood from Good Catch; new real cheese and butter made purely from plants from Miyoko’s; artisan plant meat from No Evil; creamy faba butter and decadent cookies from Fora Foods; 100% plant-based tomato sauce from Otamot; the original coconut ice cream from NadaMoo!; and so much more.

In addition to the exhibit hall, there were three keynote presentations, three education programs and several feature areas. Nil Zacharias, Founder of Eat for the Planet moderated the Friday and Saturday opening keynotes: 1. An informative and insightful keynote presentation with leaders from the Plant-Based Foods Association, Kroger Merchandising Consulting at 84.51 and Restaurant Associates. These leaders discussed the double-digit growth of the industry, catering to the one-third of Americans who now identify as “flexitarian’s”, aiming to reduce their meat and dairy consumption, causing the industry to reach into the mainstream.

2. A conversation with Seth Goldman, Executive Chair of Beyond Meat on turning a mission-driven business into a mainstream revolution. Seth who is also co-founder of Honest Tea shared his journey and discussed what’s next for Beyond Meat, his thoughts on the growing plant-based food industry and innovative new food trends he expects to emerge in the decades ahead.

PLANT BASED NEWS

The Eat for the Future Business Forum, produced in partnership with Eat for the Planet, featured speakers including executives from StrayDog Capital, Bareburger, Wicked Kitchen/Tesco, The Good Food Institute, and Hain Celestial to name a few. The Forum was designed for retail, food service, product manufacturers, plantbased food companies and food industry professionals to learn about the growth in consumer demand for plant-based foods.

The Food Solutions for Human Health Summit presented by The Plantrician Project offered a stellar line-up of leading doctors, dietitians, and nutritionists who talked about the biochemical, physiologic, and disease-specific effect of a whole food plant-based diet. Speakers included Dr. Joel Fuhrman; T. Colin Campbell, Ph.D.; Dr. Michael Greger, NutritionFacts.org, and more.

At the close of the event, NFL Linebacker Derrick Morgan and his wife Chef Charity Morgan presented a dynamic discussion on their transition to a plant-based lifestyle and the benefits Derrick and his Tennessee Titan teammates experienced. Other speakers who shared their stories with the general public during Community Day included Eric Adams, Brooklyn Borough President; Keith Tucker of Hip Hop is Green; vegan Olympians and bodybuilders such as Dostie Bausch and Nimai Delgado, and physicians such as Dr. Garth Davis and Dr. Robert Osfeld of Montefiore Health System.

The Siddhi Speaker Series offered standing room only crowds’ information from presenters who offered the latest details on a wide range of topics about marketing for vegan business success, health benefits for optimal human performance, and breakthroughs in plant-based nutrition.

The Culinary Demo Theater featured live cooking demonstrations that showcased unique plant-based ingredients and inspired home cooks and professional chefs with ideas for new menu items. Vedge co-owner Richard Landau prepared pan seared, peppercorn crusted tofu with ragu of spring vegetables and Vegan Pastry Chef Fran Costigan prepared ganache glazed chocolate cake with vanilla bean pastry cream and spring berries. Local NYC plant-based establishments such as Blossom Du Jour and Candle Cafe participated as well. Attendees also sampled delicious dishes made with seaweed, plant-based butter, seafood, and much more.

27 / THE HUB - IHR / SHOW ISSUE 2019

The expo hall was packed with professionals and consumers who tasted and sourced plant-based products from 125 exhibitors and sponsors.

PLANT BASED NEWS

Jennifer Abbasi JAMA. Published online June 12, 2019. doi:10.1001/jama.2019.6544

Cardiovascular Corner Low Lipids, Metformin, and Plant-Based Diets

28 / THE HUB - IHR / SHOW ISSUE 2019

LOW LIPIDS AND HEMORRHAGIC STROKE Very low levels of low-density lipoprotein cholesterol (LDL-C) or low levels of triglycerides were associated with an increased risk of hemorrhagic stroke among women in a prospective cohort study recently published in Neurology. Prior studies have linked low lipid levels to bleeding strokes, but sex-specific data haven’t been available until now.

Researchers examined data from 27 937 participants in the Women’s Health Study, most of whom were not taking lipid-lowering therapies at baseline. Over an average 19.3 years of follow-up, there were 137 incidents of hemorrhagic stroke. The strokes were more than twice as likely to occur among the 3.8% of women with LDL-C levels lower than 70 mg/ dL relative to those with levels ranging from 100 to 129.9 mg/dL, the reference range. And compared with women in the top quartile of triglycerides, those in the lowest quartile also had 2 times the risk of hemorrhagic stroke.

PLANT BASED NEWS

Women with LDL-C levels ranging from 130 to 159.9 mg/dL or 70 to 99.9 mg/dL did not have a greater risk of hemorrhagic stroke in the study. But the researchers did find a nonsignificant suggestion of increased risk in women with high levels of LDL-C at or above 160 mg/dL. Other studies have not explored whether high LDL-C levels are associated with hemorrhagic strokes, according to Rist, so further research is needed.

METFORMIN’S CARDIOPROTECTIVE EFFECT A 2000-mg daily dose of metformin improved left ventricular hypertrophy (LVH) in a proof-of-concept randomized clinical trial involving 68 patients who did not have diabetes but had coronary artery disease (CAD) and insulin resistance, prediabetes, or both. Published recently in the European Heart Journal, the results bolster observational data that suggest metformin is cardioprotective and raise the possibility of using the drug in patients with CAD who don’t have diabetes, the study’s authors said.

“Important to manage other risk factors for hemorrhagic stroke among these women, such as hypertension or smoking.” consequence of high blood pressure. However, normotensive patients with obesity or insulin resistance can also develop the condition, highlighting the need for new treatment strategies beyond blood pressure control.

In the 12-month trial, prolonged-release metformin significantly reduced left ventricular mass indexed to height compared with placebo. The diabetes drug also reduced body weight, systolic blood pressure, and a biomarker for oxidative stress—changes that could underpin its effect on LVH, according to Chim Lang, MD, the study’s senior author and head of the division of molecular and clinical medicine at the University of Dundee School of Medicine in Scotland.

The results from an ongoing larger trial could provide conclusive evidence of metformin’s cardioprotective effects, Lang said.

RED MEAT VS PLANT-BASED PROTEIN Substituting red meat with high-quality plant protein sources was associated with more favourable changes in cardiovascular risk factors relative to dietary replacements combined in a recent meta-analysis of randomized clinical trials (RCTs) published in Circulation.

Previous findings from RCTs that evaluated the effects of red meat on cardiovascular disease risk factors have been inconsistent.

However, when comparing outcomes, those studies combined non–red meat diets, which varied considerably in quality and composition.

A serious risk factor for adverse cardiovascular outcomes, LVH—thickening of the heart’s main pumping chamber—is largely a

The new study, which included 36 trials involving 1803 participants, is the first to separately compare diets high in red meat with those high in other types of foods, according to lead author Marta Guasch-Ferré, PhD,

a research scientist in the department of nutrition at the Harvard T.H. Chan School of Public Health in Boston. Comparison diets were stratified by high-quality plant protein; chicken, poultry, and fish; fish only; poultry only; mixed animal protein sources including dairy; low-quality refined grains and simple sugars; or usual diet.

Based on this analysis, diets with more high-quality plant protein from sources such as legumes, soy, and nuts were linked to lower levels of both total and LDL cholesterol compared with red-meat heavy diets. However, when diets with red meat were compared with all other types of diets combined, no significant differences in total cholesterol, lipoproteins, or blood pressure were found. Only triglyceride levels were elevated with red meat consumption compared with other diets combined.

Surprisingly, red meat-heavy diets appeared to lower cholesterol levels more than fish diets.

Long-term, well-designed studies are needed to confirm this. “The potentially beneficial effects of red meat consumption versus fish on total cholesterol and LDL-C observed in our analyses may mostly reflect studies in which participants consumed lean, unprocessed meat and both interventions adhered to nutritional recommendations,” Guasch-Ferré said.

“The main takeaway message should be to encourage the intake of legumes, nuts, vegetable fats, oils, and other foods from plant sources while the intake of animal fats, and particularly red and processed meat, should be discouraged,” she added.

The findings also underscore the importance of the comparison diet when assessing the effects of nutrients or foods, Guasch-Ferré said. High-quality plant protein sources generally have higher proportions of polyunsaturated fatty acids and fibre than red meat, and no cholesterol, potentially leading to health improvements, but red meat may have null or more beneficial effects on cardiovascular risk factors than do refined grains or added sugars.

However, Guasch-Ferré cautioned that most of the individual studies included in the meta-analysis were small and that dietary intervention trials sometimes have low compliance, which could minimize differences between comparison diets. She also noted that the total diet could modify the effects of individual foods on lipid parameters.

29 / THE HUB - IHR / SHOW ISSUE 2019

Although very low LDL-C levels are not considered a risk factor for heart attack and ischemic stroke, the findings suggest this may not be the case for hemorrhagic stroke. Low cholesterol may affect the integrity of the vessel walls, making them more susceptible to bleeding events, said lead study author Pamela Rist, ScD, an associate epidemiologist at Brigham and Women’s Hospital and an assistant professor of medicine at Harvard Medical School in Boston. Given this, it’s “important to manage other risk factors for hemorrhagic stroke among these women, such as hypertension or smoking,” Rist told JAMA.

PLANT BASED NEWS

The world largest meat processor Tyson Foods Unveils Alternative Protein Products and New Raised & Rooted® Brand As part of efforts to expand its protein offerings, Tyson Foods, Inc. (NSYE: TSN) today introduced the company’s first plant-based and blended products, along with its new Raised & Rooted® brand. The initiative makes Tyson Foods the largest U.S. meat producer to enter the growing alternative protein segment with its own products.

30 / THE HUB - IHR / SHOW ISSUE 2019

The Raised & Rooted brand was created to provide great-tasting plant-based and blended foods that are rooted in how people eat today.

The initial products under this new brand, which will launch with several major retail customers this year, include plant-based nuggets as well as blended burgers made with a combination of beef and plants.

In addition, the company’s existing Aidells® brand has launched Aidells Whole Blends™ sausage and meatballs, made with chicken and plantbased ingredients.

PLANT BASED NEWS

fat than traditional nuggets. The blended burger is made with Angus beef and pea protein isolate and has fewer calories and less saturated fat than the plant-based burgers sold by several competing companies.

Aidells® Whole Blends™ products include a portfolio of fully-cooked sausage links and meatballs made with a blend of high quality, no antibiotics ever chicken and plant-based ingredients such as chickpeas, black beans, quinoa, lentils and barley.

Major retail and foodservice customers have expressed interest in what Tyson Foods can bring to the alternative protein segment, which is estimated to be a multi-billion-dollar category and continues to grow. The company’s depth and breadth of experience in protein product development, manufacturing, distribution and marketing, makes it uniquely positioned to introduce new plant-based and blended proteins, and drive growth.

“Today’s consumers are seeking more protein options so we’re creating new products for the growing number of people open to flexible diets that include both meat and plant-based protein,” said Noel White, president and CEO of Tyson Foods. “For us, this is about ‘and’ – not ‘or.’ We remain firmly committed to our growing traditional meat business and expect to be a market leader in alternative protein, which is experiencing double-digit growth and could someday be a billion-dollar business for our company.”

Earlier this year, White selected Justin Whitmore to lead all aspects of Tyson Foods’ alternative proteins business, channeling Tyson Foods’ capabilities to provide consumers with exciting new protein options.

“The creation of the Raised & Rooted brand is an excellent example of Tyson’s ability to think big and move fast, capitalizing on our existing infrastructure,” said Whitmore. “We began development of our alternative protein products last year and

have succeeded in creating a new brand and bringing those products to market in well under a year. Customers tell us they love the taste and nutritional attributes and are excited to partner with us.”

“While most Americans still choose meat as their primary source of protein, interest in plant and blended proteins is growing significantly,” added Noelle O’Mara, Tyson Foods’ chief marketing officer. “These products appeal to a broad cross section of consumers who enjoy food from a variety of protein sources and we expect interest to continue to grow across protein types. The Raised and Rooted launch and our pipeline of innovation will reflect our consumers expectations for 100% plant based, blended, and traditional protein offerings.”

The Raised & Rooted® nuggets will launch through national retailers in late summer and the blended burgers this fall. The products have been developed by Tyson Foods’ innovation, culinary and consumer insights teams in Chicago and Northwest Arkansas.

The Raised & Rooted nuggets are made from a blend of pea protein isolate and other plant ingredients and contain five grams of fiber and omega-3s, and less saturated

Through Tyson Ventures, the company’s venture capital fund, Tyson Foods also continues its investment in start-up companies involved in alternative proteins. Current investments include mushroom-based protein producer MycoTechnology and cellbased meat producers Memphis Meats and Future Meat Technologies.

ABOUT TYSON FOODS Tyson Foods, Inc., (NYSE: TSN) is one of the world’s largest food companies and a recognized leader in protein. Founded in 1935 by John W. Tyson and grown under three generations of family leadership, the company has a broad portfolio of products and brands like Tyson®, Jimmy Dean®, Hillshire Farm®, Ball Park®, Wright®, Aidells®, ibp®, and State Fair®. Tyson Foods innovates continually to make protein more sustainable, tailor food for everywhere it’s available and raise the world’s expectations for how much good food can do.

Headquartered in Springdale, Arkansas, the company had 121,000 team members at September 29, 2018. Through its Core Values, Tyson Foods strives to operate with integrity, create value for its shareholders, customers, communities and team members and serve as a steward of the animals, land and environment entrusted to it.

Visit www.tysonfoods.com 31 / THE HUB - IHR / SHOW ISSUE 2019

Tyson Foods expects to introduce additional alternative protein products through multiple customers and sales channels.

This includes products under the Raised & Rooted brand and across the company’s portfolio of iconic brands, as well as to foodservice operators.

PLANT BASED NEWS

Less Processed Meat, More Plant-Based Foods May Boost Longevity 32 / THE HUB - IHR / SHOW ISSUE 2019

Authors: Yan Zheng, professor1,2,3, Yanping Li, research scientist3, Ambika Satija, research fellow3, An Pan, professor4, Mercedes Sotos-Prieto, assistant professor3, 5, 6, 7, Eric Rimm, professor3, 8 ,9 , Walter C Willett, professor3, 8 ,9 , Frank B Hu, professor3, 8 ,9 A large body of evidence has shown that higher red meat consumption, especially processed red meat, is associated with an increased risk of type 2 diabetes,1 cardiovascular disease,2 certain types of cancer, including colorectal cancer,3 and mortality.45 Consumption of processed red meat (eg, bacon, hot dogs, and sausages) has been associated with additional health outcomes, including chronic obstructive pulmonary disease,6 heart failure,7 and hypertension.8 Components of red and processed meats such as proatherosclerotic lipids (eg, saturated fat),9 potential carcinogens (eg, polycyclic aromatic hydrocarbons),10 sodium, and preservatives could contribute to adverse health outcomes.

PLANT BASED NEWS

Analyze of the association of changes in red meat consumption over eight years with mortality risk during the subsequent eight years. have analyzed the relation between red meat consumption and mortality risk. In this study, we examined whether changes in red meat intake are associated with subsequent risk of total and cause-specific mortality.

Analyze of the association of changes in red meat consumption over eight years with mortality risk during the subsequent eight years. Participants were US women from the Nurses’ Health Study and US men from the Health Professionals Follow-up Study.

The Dietary Guidelines for United States 2015-2020 include the recommendation: “Strategies to increase the variety of protein foods include incorporating seafood as the protein foods choice in meals . . . and using legumes or nuts and seeds in mixed dishes instead of some meat or poultry.”12 Therefore, we used statistical models to estimate the effects of replacing red meat with equivalent amounts of other protein sources, such as nuts, poultry, fish, dairy, eggs, and legumes, and whole grains and vegetables.

STUDY POPULATION The Nurses’ Health Study is a prospective cohort study of 121 700 US registered female nurses aged 30-55 at enrollment. The study started in 1976 and nurses completed a baseline questionnaire about demographic factors, diet habits, lifestyle, and medical history.

The Health Professionals Follow-up Study was established in 1986 when 51 529 US male health professionals aged 40-75 returned a baseline questionnaire about detailed medical history, lifestyle, and usual diet. In both cohorts, questionnaires were completed biennially after baseline to collect and update information on lifestyle and occurrence of new-onset diseases. The follow-up rates were approximately 90% for both cohorts. Detailed descriptions of the cohorts have been published elsewhere.1314 The baseline of the current analysis was set as 1994, which is eight years after 1986 when detailed information on diet, physical activity, and other lifestyle factors was collected for both cohorts. The end of follow-up was 2010. The researchers excluded participants who had a history of heart disease, stroke or cancer, missing information on diet and lifestyle covariates, extreme energy intake (men: <800 or >4200 kcal/day; women: <500 or >3500 kcal/day; 1 kcal=4.18 kJ=0.00418 MJ), or those who died before baseline (that is, 1994). The final analysis included 53 553 women and 27 916 men.

DIETARY ASSESSMENT The two cohorts completed a validated semiquantitative food frequency questionnaire in 1986 and every four years thereafter. Participants were asked how often, on average, they consumed a standard portion of each food in the past year.

Frequency response categories ranged from never or less than once a month, to six or more times each day. Questionnaire items on unprocessed red meat (one serving, 85 g) included beef, pork, and lamb as a main dish; hamburger; and beef, pork, or lamb as a sandwich or mixed dish. Items on processed red meat included bacon (one serving, two slices, 13 g), hot dogs (one serving, one hot dog, 45 g), and sausage, salami, bologna, and other processed red meats (one serving, one piece, 28 g). Total red meat included unprocessed and processed red meat. The reproducibility and validity of the food frequency questionnaire have been described elsewhere151617 and show good correlations with several weeks of food records.16 For the

Health Professionals Follow-up Study, the corrected correlation coefficients between the food frequency questionnaire and multiple dietary records were 0.59 for unprocessed red meat and 0.52 for processed red meat18; we observed similar correlations for the Nurses’ Health Study.16 In a subcohort of the Nurses’ Health Study (n=3690), higher red meat consumption was associated with unfavourable plasma concentrations of inflammatory and glucose metabolic biomarkers.19 In the current study, we calculated a modified diet score of the alternative healthy eating index to assess overall diet quality after removing the red meat components.17

ASCERTAINMENT OF MORTALITY Death from any cause was the primary outcome of this analysis. We identified deaths by using the state vital statistics records, the national death index, reports by families, and the postal system.20 Using these methods, we ascertained 98% of deaths in each cohort.20 We sought death certificates for all deaths, and when appropriate, requested permission from the next of kin to review medical records. A physician reviewed death certificates and medical records and determined the underlying cause of death according to the ICD-8 and ICD-9 (international classification of diseases, eighth and ninth revisions). We grouped causes of death into six major categories.

33 / THE HUB - IHR / SHOW ISSUE 2019

Red meat is a major component of dietary patterns in Western populations. The average consumption of red meat in the United States has decreased in recent decades, but it remains more than twice the global average.11 Several epidemiological studies

PLANT BASED NEWS

of one serving per day of poultry (no skin), fish, dairy products, eggs, legumes, nuts, whole grains, or vegetables (no legumes).

Concurrent changes were included in all these food sources, in addition to red meat, in the same multivariable model. The difference in the coefficients for change in red meat and change in the alternative food was used to estimate the hazard ratio; the corresponding variances and covariance were used to estimate 95% confidence intervals.24

34 / THE HUB - IHR / SHOW ISSUE 2019

COVARIATES MEASUREMENT Information on potential confounders was assessed and updated biennially. These confounders included age, race, family history of myocardial infarction, diabetes or cancer, weight, smoking status, aspirin use, multivitamin use, menopausal status and postmenopausal hormone therapy use for women, physical activity, and physician-diagnosed hypertension, diabetes, or hypercholesterolemia. Alcohol consumption was assessed and updated from the food frequency questionnaire every four years. Height and weight were used to calculate body mass index. Detailed descriptions of the validity and reproducibility of self-reported body weight, physical activity, and alcohol consumption have been published elsewhere.212223 STATISTICAL ANALYSIS Researchers calculated the follow-up person-years from the date of returning the 1994 questionnaire to the date of death or the end of follow-up, whichever came first. Updated eight-year change in red meat consumption was used as the time-varying exposure. We used time-dependent Cox proportional hazards regression to estimate the hazard ratios and 95% confidence intervals of total and cause-specific mortality in the subsequent eight years; that is, changes in red meat consumption between 1986 and 1994 predicted mortality in 1994-2002, and changes in red meat consumption between 1994 and 2002 predicted mortality in 2002-10. We divided participants into five categories based on their changes in red meat consumption: two increase categories (increase of >0.5 serving per day or 3.5 servings per week; increase of 0.15-0.5 serving per day or 1-3.5 servings per week); two decrease categories (decrease of >0.5 serving per day or 3.5 servings per week; decrease of 0.15-0.5 serving per day or 1-3.5 servings per week), and one reference category (increase or decrease of <0.15 serving per day or <1 serving per week). We also calculated hazard ratios and the corresponding 95% confidence intervals for changes in red meat consumption.

We adjusted multivariable models for initial age, calendar year as the underlying time scale, race (white v other), family history of myocardial infarction, diabetes, or cancer (yes v no), initial aspirin use (yes v no), and initial multivitamin use (yes v no). We also adjusted for initial consumption of red meat (in fifths); body mass index categories (<23,

23-24.9, 25-29.9, 30-34.9, and ≥35); menopausal status and hormone therapy use in women (premenopausal, postmenopausal and hormone therapy never user, postmenopausal and hormone therapy current user, postmenopausal and hormone therapy past user, or missing indicator); simultaneous changes in smoking status (never to never, never to current, former to former, former to current, current to former, current to current, or missing indicator); initial and simultaneous changes in physical activity, alcohol consumption, total energy intake, and other main food groups, including vegetables, fruits, whole grains, and sugar-sweetened beverages (all in fifths). In an additional model, we further adjusted for initial history of hypertension, hypercholesterolemia, or diabetes (all yes v no), and simultaneous weight change (in fifths), which were potential mediators of the association between red meat changes and mortality. Unprocessed and processed red meat changes were also estimated separately. Stratified analyses were performed a priori by treating total red meat change as a continuous variable according to initial age, body mass index, smoking status, physical activity, alcohol consumption, and modified the alternative healthy eating index.

The significance of the interaction terms was tested by including cross-product terms for each category and change in red meat consumption in the multivariable models.

As well the risk of death examined associated with a decrease in red meat by one serving per day and a simultaneous increase

In secondary analyses, short term (four years) and long term (12 years) changes in red meat consumption for associations were estimated with total mortality (four-year change in red meat consumption predicted four-year follow-up and 12-year change in red meat consumption predicted 12-year follow-up).

Researchers also modelled associations of a decrease of one serving per day of red meat substituted with an alternative food over four years with total mortality in the subsequent four years and the same substitution over 12 years with total mortality in the subsequent 12 years.

We calculated hazard ratios and 95% confidence intervals from the different models separately for each cohort, and then we pooled the results by using an inverse variance weighted meta-analysis with the fixed effects model. Analyses were performed with SAS version 9.4 for UNIX (SAS Institute, Cary, NC). Statistical tests were two sided and a P value less than 0.05 was considered statistically significant.

PATIENT AND PUBLIC INVOLVEMENT No patients were involved in setting the research question or the outcome measures, nor were they involved in the design and implementation of the study. No plans exist to involve patients in dissemination.

In the Nurses’ Health Study, 8426 deaths were identified during the follow-up (804 685 person-years): 1774 deaths from cardiovascular disease, 3138 from cancer, 939 from neurodegenerative diseases, 751 from respiratory diseases, and 1824 from other causes. In the Health Professionals Follow-up Study, we identified 5593 deaths during follow-up (409 073 person-years): 1754 deaths from cardiovascular disease, 1754 from cancer, 434 from respiratory diseases, 375 from neurodegenerative diseases, and 1276 from other causes.

Source: BMJ

An ounce of prevention is worth a pound of cure.

Enjoy the potent benefits of garlic, daily.

• Garlic cloves have a central core with an enzyme called allinase. There is also a compound called alliin. When these two compounds combine, they create allicin; • Allicin is the substance responsible for the anti-microbial properties of garlic; • In the late 1990s/early 2000s, Dr. Peter Josling led a team to stabilize the allicin and Allimax was born! Allimax is used around the world to kill funguses, viruses, and bacteria; • It can also prevent coughs and colds and it can boost an underactive immune system.

VISIT US AT BOOTH #1645 TO LEARN HOW TO SHARE IN THE SUCCESS OF ALLIMAX.

www.clmhealth.com Contact us: 877-263-7330

36 / THE HUB - IHR / SHOW ISSUE 2019

COVER STORY

A Fleur de Vie

COVER STORY

37 / THE HUB - IHR / SHOW ISSUE 2019

Celebrating 37 years of Health and Community!

COVER STORY

Located in the Sherbrooke province of Quebec, a university city with over 40,000 students, Sherbrooke ranks 20th among Canadian cities with a population density of 212,000. Sherbrooke is nearly a two hour drive from beautiful Montreal and for a community of this size, it’s health food store offerings are impressive; with eight natural health food/supplements stores in the region.

Our mission is to provide a deep understanding of our client’s needs.

38 / THE HUB - IHR / SHOW ISSUE 2019

With such a density of health food stores, our mission is to respond to the specific needs of our community and to offer the capacity, originality, creativity and vision to offer outstanding service to our clients.

At Fleur de Vie we aim to provide much more to our clients than simply offering our a competative price. Our mission is to provide a deep understanding of our client’s needs and to be able to offer judicious advice that can help make a real difference in the lives of our clients. Our clients return to us because of the quality of service they receive and the results they experience when following our advice on their health needs.

HISTORY Lucie Bisson, the visionary founder of the famous A Fleur De Vie, has been established in the Sherbrooke community for almost 40 years. She purchased the business in 1985, at a time when there were very few natural health products on the market. Shortly after, Lucie’s brother Sylvain Bisson joined A Fleur De Vie and placed an emphasis on providing therapeutic advice to clients. This quickly established customer loyalty where clients appreciated a close approach to their health needs and where products could be catered to them specifically.

Sylvain came to be know as the man who could provide answers to complicated health questions and concerns, even to other practitioners; and Émilie Belleville has a Bachelors Degree in biology and a degree in Naturopathic Medicine. Her role at A Fleur De Vie has been placing projects into action! Today A Fleur De Vie is running with this successful trio serving the community.

THE MOVE In March 2017, A Fleur De Vie moved to a larger location to be able to accommodate a larger inventory of products and be able to provide customers with even more opportunity to come to A Fleur De Vie for advice on their health needs.

The new store offers 2000 square feet with private areas to provide clients with consultations. The second floor boasts offices, consultation rooms and a conference room.

Despite the increase of several health stores in recent years, A Fleur De Vie remains a local institution that is a staple in Sherbrooke, proving that taking a deep interest in clients’ needs leads to loyalty, integrity and success. Bravo on 40 years well served!

39 / THE HUB - IHR / SHOW ISSUE 2019

COVER STORY

STUDY

Curcumin BioBDMC30™

By Franco Cavaleri BSc PhD candidate (www.biologic-med.com)

40 / THE HUB - IHR / SHOW ISSUE 2019

Medical Discovery on Curcumin Research – Prevention is the best Cure You’ve likely encountered the topic of Curcumin circulating around the dinner table, and we’re not just talking about eating it. Curcumin (a compound derived from Turmeric) dates back over 5,000 years but is gaining in popularity in the West as news spreads about its many benefits. So what’s all the hype about?

Current therapeutic research on curcumin technology indicates that the curcumin compound can be engineered in a multitude of ways; to be targeted to treat joint disease or engineered broadly to counter general or subclinical inflammation that slowly degrades the body and may even contribute to premature aging.

Curcumin is noted to be one of the more potent anti-inflammatory agents among natural therapies. It has been used in the treatment of Alzheimer’s, colitis, Crohn’s, arthritis, hypertension, hypercholesterolemia, joint relief and so much more; and although research does support the effectiveness of Curcumin in treating these conditions, it isn’t until recently that research is pointing us to the true potential that has been semi-dormant in the curcumin extract.

Inflammation lies at the core of every disease challenging humans and tends to escalate slowly as we age. For example, research shows that as insulin efficiency declines (insulin resistance advances with age) Nitric Oxide (NO) levels in the active worker joint cells increases while oxidative control declines. This translates into a higher risk for joint degeneration and inflammation. NO is highly reactive and in the presence of the superoxide free radical (commonly escalated with inflammation) it is quickly converted to peroxynitrite (ONOO). This nasty free radical fuels inflammation and is known to damage DNA and kill cells.

Once this inflammatory cycle begins, it can be self-perpetuating, turning NO into more ONOO – and intensifying the inflammatory activity in nearby tissue. In addition to this degenerative activity at the joint level, bone mass can be significantly affected by this inflammation and can lead to osteoporosis; it’s an overall inflammatory cloud that creeps up and interferes with metabolism with little warning. Unfortunately, our toxic environments and lifestyles do little to abate these degenerative effects, instead adding more fuel to the fire and causing the body to produce inflammatory hormones that can further contribute to age-related inflammation and interfere with life-preserving processes.

parts of the ageing process, yet we can have some counteractive control.

Curcumin can play a pivotal role in counterbalancing the above degenerative issues but it must be used correctly and isolated and extracted properly. Regular old Curcumin (even 95% pure Curcumin) is not a reliable option and usually not potent enough to deal with deep rooted inflammation.

Curcumin can play a pivotal role in counterbalancing the above degenerative issues but it must be used correctly and isolated and extracted properly.

Inflammation thwarts the balanced activity of highly specialized cells that are responsible for managing calcium in the body – primarily the osteoclast and the osteoblast. Osteoclasts are specialized cells that extract calcium from bone shuttling it into the body where it might be needed for important metabolic tasks while the bustling osteoblast has an opposing role; picking up free calcium and incorporating into bone matrix to build bone.

This remodelling is a constant process that turns over tissue and restores and repairs.

The state of your bone mass is a function of these two opposing forces. No matter how much calcium, magnesium and vitamin D you consume in food or supplemental form, bone mass will be limited to the net balance created by these two worker cells which in turn are intensely modulated by the chemistry of inflammation.

The latest research discovery at Biologic Pharmamedical Research shows us that underlying curcuminoid components in the curcumin extract have very different drug target activity. There are three main curcuminoids in the curcumin extract and they can vary significantly in proportion to eachother.

Many diseases, especially those related to autoimmunity, add yet another layer to the inflammatory cloud, further compounding the problem; and Inflammation, believe it or not, also plays a central role in fat mass accumulation and even depression. These are many of the features we attribute to aging and regression, accepting them as normal

This recent research has focussed on separating, isolating and mapping the pharmacology of these curcuminoid components in the context of multiple key proteins in this inflammatory pathway. The key active curcuminoid fraction of this discovery is increased to 30% (ie BioBDM30) while regular curcumin only has 1% (ie BioBDM1)

of this key curcuminoid active. Each curcuminoid portion is locked in for consistency and standardized to be reliable from lot to lot to provide activity at two important points in the inflammatory pathway; not just one.

The inflammatory pathway is comprised of a plethora of proteins that affect and regulate the course of inflammation in our cells and throughout the body. Inhibiting or slowing down one protein helps slow inflammation by shutting down two that are central keys to the long pathway. This shuts down inflammation quickly and reliably each time.

This new discovery allows us to engineer curcumin to neutralize two key proteins in the common inflammatory pathway instead of one protein like regular curcumin 95%. This results in a more reliable anti-inflammatory activity that works faster (within hours instead of days) and more potently than with regular curcumin extracts.

The findings at Biologic Pharmamedical Research have led to game changing insight that puts a completely new perspective on curcumin, establishing a new standard of natural drug design that is being accepted world-wide.

The result of this novel curcumin standard pharmacology is BioBDM30™ -reliable curcuminoid composition standardization; more effective measurement of activity; and consistent activity for curcumin that also exceeds 95% concentration!

The patented ‘Curcumin BioBDMC30™’ and Curcumin BDMC50™’ ingredients are the new household names being used in the higher quality curcumin-based products on retail shelves. Curcumin BioBDMC30™’ and BDMC50™’ are designed to help counter the forces of aging, help regulate inflammation to protect bones, joints and against general biological ageing. Prevention is key when addressing inflammation and neutralizing its damaging effects on the body. Taking curcumin BioBDMC30™’ or BDMC50™’ can abate daily inflammation before it has a chance to damage joints, bones and other tissue.

When looking for a Curcumin based product, look for brands that are using this next generation of ani-inflammatory support.

The long terms benefits will be immeasurable to your overall health, especially as the years progress.

41 / THE HUB - IHR / SHOW ISSUE 2019

C30

STUDY

STUDY

urmeric’s Extraction Methods for Supplements Turmeric and curcumin continue to be praised.

According to the National Institutes of Health, “preliminary studies have found that curcuminoids may reduce the number of heart attacks bypass patients had after surgery, control knee pain from osteoarthritis as well as ibuprofen did and reduce the skin irritation that often occurs after radiation treatments for breast cancer.”

42 / THE HUB - IHR / SHOW ISSUE 2019

Which supplements should you choose? It largely comes down to the extraction method that is used in production and bioavailability.

There have been a number of attempts made by researchers to increase the bioavailability of turmeric in supplements, with little success. The main strategy has been through the use of additives or adjuncts, such as black pepper. The end result has been a good number of turmeric products on the market that offer questionable bioavailability of turmeric’s goodness.

What is the Difference between Turmeric and Curcumin?

Although turmeric and curcumin are different substances, they do come from the same plant, which is why they are often confused as the same substance. Turmeric comes from a plant that is also called Curcuma longa, or C. longa. Curcumin is extracted from the root of the turmeric plant. Curcuminoids are the compounds that are extracted from the turmeric root. The three main curcuminoids are curcumin, demethoxycurcumin and bisdemethoxycurcumin.

Curcumin is most well-known curcuminoid because it is believed to contain the greatest amount of medicinal properties. The whole turmeric compound has been shown to contain all of these cucuminoids. Thus, although turmeric and curcumin are not the same

substance, curcumin is part of the root of turmeric. What makes curcumin so special? Although it is believed that curcumin only comprises 2-6 percent of the turmeric spice, curcumin is believed to offer powerful antioxidant and anti-inflammatory characteristics.

As a result, curcumin is believed to be the most active component of turmeric. Despite these findings, the other curcuminoids have been found to be important components of turmeric.

Is it Better to Take Turmeric or Curcumin?

You’ll want to educate your consumers that is believed to be better to consume turmeric in supplement form rather than curcumin alone (just one component of turmeric) because curcumin is only one of the cucuminoids (compounds offering medicinal properties that are extracted from the turmeric root) in turmeric.

The three curcuminoids (curcumin, demethoxycurcumin and bisdemethoxycurcumin) are part of a group called polyphenol phytochemicals. These are plant chemicals have been associated with powerful anti-inflammatory properties. They may also help to support your immune system and may help encourage protection against a wide variety of chronic illnesses.

In addition to these chemicals, turmeric is associated with over 200 additional phytochemicals. Turmeric is believed to be anti-inflammatory, antibacterial and antimicrobial. The challenge with consuming turmeric and curcumin is that these substances are difficult for the body to absorb.

A NEW EXTRACTION METHOD FOR TURMERIC New research is helping to improve the bioavailability of turmeric, thus we can expect to see changes in the marketplace in

STUDY

WHAT EXACTLY IS TURMERIC?

Used as a natural medicine for thousands of years, turmeric is a spice that comes from the turmeric plant, which grows in India and Indonesia. It is a common ingredient in South Asian cuisine. Turmeric is known to offer natural pain relief due to its chemical properties. Turmeric has been shown to be anti-inflammatory, antibacterial and antimicrobial. It has been shown to support cardiovascular health, gastrointestinal health, musculoskeletal health, blood sugar levels and it may offer many additional health benefits.

the near future. A new curcumin extract being marketed under the brand name “Curcumin BDM30TM” was developed with high levels of the curcuminoid bisdemethoxycurcumin (BDMC). Due to its high BDMC content, this product is said to target inflammation differently from other curcumin extracts on the market.

The Rhema Group (Ogden, UT) partnered with Biologic Pharmamedical Research (Vancouver, BC, Canada) to produce the ingredient. According to Rhema’s chief science officer, Franco Cavaleri, BSc, PhDc, who is also the principal research scientist at Biologic Pharmamedical, Curcumin BDM30TM’s high BDMC content enables it to inhibit the activity of the nuclear MSK1 protein, which is a “facilitative kinase protein central to the inflammatory process, specifically NF-kB transactivation.” Cavaleri said that according to his research, the regular curcumin extract itself, cannot inhibit this regulatory kinase, MSK1 while BDMC does with significance.

“This discovery is significant because it means curcumin pharmacology can now be more precisely targeted for therapeutic results,” says Cavaleri. The companies say that the work they are doing to develop “new evidence-based” curcumin drug and supplement ingredients “is expected to change how curcumin is prescribed in the future to help improve lives.”

How Should Turmeric Be Sold?

As a retailer, turmeric supplements should be an important component of your joint care category. A growing body of scientific research supports turmeric’s health benefits with respect to pain and inflammation. Since the turmeric spice (the powder form at the grocery store is the root ground up) is poorly absorbed and must be consumed in a concentrated form to obtain its full medicinal effects, a quality turmeric supplement is necessary for consumers to enjoy the many health benefits it offers. Poor absorption from the gut and rapid metabolism in the body are the main reasons for the lack of whole-body bioavailability. That is why turmeric in a bioavailable supplement form is far superior to consuming the spice in whole or powder form. As a retailer, you’ll want to avoid synthetic turmeric supplements as the health benefits come from the (real) turmeric root. Also, pesticides have been a known concern in supplements, therefore, choose products that are free of them. The more turmeric supplements you offer on your shelves, the more confusing it can be for consumers. Stick with a small number of high-quality supplements (in pill form as that is the most convenient option) in this category. Turmeric supplements are plant-based, which contributes to that particular category as well.

When putting together your joint care category, be mindful of what health professionals are recommending. For example, medical doctors might recommend glucosamine for related conditions, whereas a Naturopathic Doctor might recommend curcumin. Other products that fall into the joint care category include herbs and plant-based products, bone-building minerals, enzymes, animal, marine and dairy-based products (such as collagen, eggshell membrane, etc.). These products and supplements generally fall into either being “joint builders” or inflammation calmers”. With a mix of products such as those mentioned, aim to dedicate approximately 5% of your retail space’s joint care category to turmeric supplements. More importantly, ensure you choose products that have been developed with the best extraction methods and offer the best bioavailability for your consumers.

> Pain Conditions // Inflammation can lead to pain and discomfort. Inflammation is associated with a variety of medical conditions, such as arthritis, fibromyalgia, headache, joint pain, muscle pain, neck pain, osteoarthritis, rheumatoid arthritis, sports pain and many other painful conditions. > Arthritis // Arthritis is a condition that causes inflammation of the joints. The main symptoms are stiffness and joint pain, which typically get worse as a person ages. Osteoarthritis and rheumatoid arthritis are the most common types of arthritis. Oxidative stress can lead to the degradation of cartilage in rheumatoid arthritis and osteoarthritis. > Weak Immune System // Your immune system can be weakened by oxidative stress, which can lead to the development of various chronic diseases. The three curcuminoids in turmeric (curcumin, demethoxycurcumin and bisdemethoxycurcumin) are part of a group called polyphenol phytochemicals. These are plant chemicals (antioxidants) contain powerful anti-inflammatory properties and may help protect the immune system against a wide variety of chronic illnesses.

43 / THE HUB - IHR / SHOW ISSUE 2019

Turmeric Benefits

www.foodarom.com

CONTINUING EDUCATION

Might Prevent Migraines

Now, some researchers think it could help people with another condition: chronic migraines.

Millions of women in America suffer from migraines, and treatments such as OTC pain medication don’t always work. So the fact that a simple lifestyle change might ease the pain and the debilitating side effects of migraines is welcome news. (These skull crushers can last for days and be accompanied by disabling nausea, vomiting, and light sensitivity.)

To find out how the diet could potentially benefit migraine sufferers, Health spoke to Mayo Clinic migraine expert Jennifer Robblee, MD, a member of the American Headache Society. She tells us that diet in general often comes into play when doctors think about ways to treat people who frequently get migraines.

But when it comes to the keto diet specifically, “the research is still quite young there.

There’s a lot for us to learn,” Dr. Robblee says. While going keto might help you if

you suffer from migraines, experts aren’t sure why.

Changing a person’s diet might help keep chronic migraines at bay. Yet right now, not enough data exists for experts to make specific recommendations. “Ketogenic diet is one that has been looked at, [but] right now there’s no one diet that has enough research for us to recommend it,” Dr. Robblee explains.

“The ketogenic diet affects your metabolism. Are you having improvements because of the weight loss? Is it the ketosis itself?

That’s still an unknown,” Dr. Robblee says.

Ketosis is the state a person’s body goes into on the keto diet, forcing their system to burn fat rather than carbs for energy (and leading to weight loss and other health benefits, keto adherents say).

“One hypothesis is that, ultimately, you’re doing a diet that has less processed foods,” says Dr. Robblee. The keto diet focuses on whole, unprocessed products, such as eggs, fatty fish, low-carb veggies, and low-sugar fruits.

Research published in 2017 drew a link between the keto diet and migraine prevention. But the research doesn’t explain exactly what the relationship between the two is.

That research called for randomized control

studies, and Dr. Robblee says we definitely need these moving forward.

Dr. Robblee says the keto diet might benefit migraine patients the same way it benefits people with epilepsy. “Both conditions have abnormal function in the brain. There is some sort of overlap. [In migraine patients,] you have this difference in the electric signal in the brain.” Some treatment options for migraines are also used to treat epilepsy, Dr. Robblee adds.

Among these is a vagal nerve stimulator, which can reduce the number of seizures an epileptic person has. (The vagus nerve connects the brain to organs in the neck, chest, and abdomen).

If you’re suffering from migraines consistently, it might be worth your while to try going keto. It could help—though right now, science is just not quite sure why.

45 / THE HUB - IHR / SHOW ISSUE 2019

Back before the keto diet became super trendy for weight loss, this high-fat, low-carb plan was created to help people suffering from epilepsy, a neurological disorder that causes abnormal brain activity.

DIET

THE

JOINT

DRIVE STORE VISITS

Leverage the latest Digital Advertising technology to

GEO-FENCE TARGET prospects and customers searching for watches and Jewellery and visiting your competitors or complementary places of business.

INCREASE

The number of phone calls you receive for your jewellery or watches and new customers that visit your business.

MONITOR

and improve your investment return with monthly proof of performance reports.

46 / THE HUB - IHR / SHOW ISSUE 2019

Create prospective consumers into real in stores buyersÂ

info@shiftclix.com

Serious Pain Relief so You can Socialize

You love being with friends or family. A sit-down for lunch, cards or laughs is right on the button. Getting with people you love is the best.

Bu But lately, arthritis is making it harder to get around. Pain and stiďŹ&#x20AC;ness are getting in the way. Try Lakota Arthritis Roll-on for amazing arthritis pain relief.

Lakota Arthritis

Roll-on pain reliever is odourless so your friends wonâ&#x20AC;&#x2122;t know the secret to the new bounce in your step.

And itâ&#x20AC;&#x2122;s natural.

Comes in a convenient hands-free applicator people love. Time tested medicine proven to work - we guarantee it.

Get Medicine that Works

Add some protein to your day the lite way.

Protein

Vegetarian options

Fibre

No GMO ingredients

Low carb options

Keto friendly options

Gluten free varieties

Made in Australia

Calorie controlled

Ideal for pre/post workout

www.slimsecrets.co