A Guide to Innovet Products

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A GUIDE TO INNOVET PRODUCTS

RESEARCH-BASED HEALTH AND WELL-BEING

ACCORDING TO NATURE

September 2024

SCIENCE ACCORDINGTONATU R E

A GUIDE TO INNOVET PRODUCTS

RESEARCH-BASED HEALTH AND WELL-BEING

ACCORDING TO NATURE

SCIENCE ACCORDINGTO

member of

RESEARCH & INNOVATION FOR THE HEALTH OF OUR FOUR-LEGGED FRIENDS

TO GO WHERE NATURE LEADS ...

... means studying and reproducing the body's natural protective responses, as opposed to counteracting artificially the negative stimuli that may affect it.

ALIA MECHANISM

The insight of the Nobel Prize Laureate in Medicine Rita Levi Montalcini led, in the nineties, to the development of a new concept of biological modulation of some neuroimmune inflammatory cells (e.g. mast cells) called the ALIA* mechanism: an endogenous system of local injury antagonism that the body activates to counteract the negative stimuli. The first identified compound acting this physiological mechanism is PEA (palmitoylethanolamide).

ENDOCANNABINOIDS

We now know that PEA is an endocannabinoid (eCB), an authentic defence mechanism that Nature has devised to counteract negative stimuli and thus keep the body healthy.

ALIAMIDES

From PEA originate the ALIAmides, a family of substances that naturally and physiologically modulates the responses of cells and tissues to negative stimuli, thus ensuring a physiological balance in the body.

Native PEA is poorly bioavailable. Through the ultra-micronization process, Innovet Research managed to obtain a much more active form patented all over the world (PEA-um, ultra-micronized palmitoylethanolamide). PEA-um, the most active form

* Autacoid Local Injury Antagonism

NEGATIVE STIMULI

DEPENDS ON THE BETWEEN NEGATIVE STIMULI AND SYSTEMS

METABOLISM

Oleea®

To keep overweight pets healthy.

Package sizes and dose forms

Oleea® Liquid 60 ml with dosing syringe

Oleea® Caps 60 skittle capsules

DOG CAT

Reduces the health risks posed by overweight/ obesity. Supports diets (lowcalorie diet) and other measures (physical activity) for reducing weight.

What it contains

• Olaliamid®

Patented derivative of olive oil rich in NAE (N-acylethanolamines), which are physiological substances that help to maintain an efficient sugar and fat metabolism.

• Vitamin E

Neutralizes free radicals (antioxidant action).

Its unique features

• Contains Olaliamid®: an innovative, patented compound developed by Innovet research.

• Improves the result of weight-loss diets.

• Safe and risk-free, can be administered for long periods.

• Two dose forms for easy administration (squeeze skittle capsules and liquid).

How to use

Administer preferably 30 to 60 minutes before meals.

Shake well, insert the graduated syringe in the hole in the bottle adapter, turn the bottle upside down and draw the daily quantity indicated in the table. Empty the content of the syringe directly in the pet’s mouth.

Open the skittle capsule as illustrated in the drawing (1) and squeeze its content into the animal’s mouth or mix it with its food ration (2). Alternatively, the skittle capsules can be swallowed whole.

- 9

10 - 14 1 -

15 - 19 1.5 -

20 - 34 - 1

35 - 52 - 2

> 52 - 3 1 2

Condrogen® Puppy

For the proper development of the puppy's joints.

Package sizes and dose forms

Condrogen® Energy 30 scored tablets

Condrogen® Energy 60 scored tablets

Condrogen® Energy 90 scored tablets

Ensures the healthy musculoskeletal development of puppies.

Ideal for large/giant breed puppies.

What it contains

• PGA-m (micronized palmitoyl-glucosamine)

Highly bioavailable patented micronized compound. Exclusive source of slow-release glucosamine.

• Chondroitin Sulfate

Nourishes the joint cartilage, contributing to its proper development, and provides resistance to injuries.

• Oxiforce complex®

Innovative combination of SOD (superoxide dismutase) and nucleotides. It guarantees joint stability by stimulating the energy.

Optimizes the growth of the soft tissues (muscles, tendons, and ligaments), improving joint stability.

Its unique features

• Acts on both the cartilage and the muscles.

• With PGA-m (ALIA effect). Physiological action.

• The exclusive micronized form (PGA-m) ensures greater bioavailability (particle size: 94% < 10 microns).

• Safe for prolonged use (useful as early treatment for dogs prone to joint problems).

How to use

To be administered directly into the dog’s mouth or mixed with the feed ration throughout the entire growth period (from 2 to 12-18 months-old).

Body weight (kg) Tabs/day

0 - 8 ½

9 - 18 1

19 - 29 1 and ½

30 - 44 2

45 - 60 2 and ½ > 60 3

Condrogen® Sport

For supporting joint performance in canine athletes.

Package sizes and dose forms

Condrogen® Sport 60 stick

Nourishes and protects the joint.

Boosts the muscle's energy metabolism. Promotes muscle recovery after exercise.

Ideal for dogs engaged in sports activities.

What it contains

• PGA-m (micronized palmitoyl-glucosamine)

Highly bioavailable patented micronized compound. Exclusive source of slow-release glucosamine.

• Selenium and Vitamin E complex Antioxidant action.

• Fish collagen

Maintains the proper elasticity of tendons and ligaments.

• Maltodextrins

Provide an immediate and constant supply of energy, and a rapid muscle recovery.

Its unique features

• Acts on both the cartilage and the muscles.

• With PGA-m (ALIA effect). Physiological action.

• The exclusive micronized form (PGA-m) ensures greater bioavailability (particle size: 94% < 10 microns).

• Protection and energy for champion joints.

• Slows down the degenerative process of the athlete dog's joints due to intense training.

• Convenient stick packs to be administered orally or mixed with food.

How to use

The content of the stick can be administered directly into the animal’s mouth or mixed with food. To be used during times of strenuous exercise, for periods of at least 60 days. For better results, it is advised to administer the product at the end of an intense physical activity session, preferably within 30 minutes, or in the interval between two runs. Body weight (kg) Stick/day

Condrostress® Mobility

To improve joint mobility of adult and senior dogs.

Package sizes and dose forms

Condrostress® Mobility 30 soft chews

Condrostress® Mobility 60 soft chews

Condrostress® Mobility 90 soft chews

Its unique features

• Nuove soft chews per una somministrazione facile e appetitosa anche negli animali inappetenti.

cartilage.

Preserves the ability to move of dogs with chronic joint problems. Protects joint

For adult and senior dogs with limited mobility.

What it contains

• Eggshell membrane

Natural source of collagen, glycosaminoglycans (chondroitin-sulfate, hyaluronic acid) and sulfur-beaaring amino acids. It protects joint cartilage from the damage caused by wear.

• Vitamin E and C

Neutralize free radicals (antioxidant action).

• Boswellia serrata

Provides relief to the joints. Strengthens joint health and mobility.

• Safe for prolonged administration to senior dogs.

• Improves the quality of life in dogs with reduces joint mobility.

• Complete formula with Boswellia serrata, against joint stiffness.

How to use

Administer directly into the mouth for 60 to 90-day periods, at the daily quantity indicated in the table. To be repeated as needed.

Condrostress (+) Cat

To improve joint mobility to adult and senior cats.

Package sizes and dose forms

Condrostress (+) Cat 30 openable capsules

Preserves the ability to move of cats with chronic joint problems. Protects joint cartilage.

What it contains

• Ovopet® (eggshell membrane)

Biological matrix, a natural source of collagen, glycosaminoglycans (chondroitin sulfate, hyaluronic acid) and sulfur-bearing amino acids. It protects joint cartilage from the damage caused by wear.

• Omega-3 fatty acids (EPA and DHA)

Support the correct function of the synovial membrane.

• Vitamin E Neutralizes free radicals (antioxidant action).

Its unique features

• Safe for prolonged administration to senior cats.

• Improves the quality of life of cats with reduced joint mobility.

How to use

Open the capsule and pour its contents onto the food or directly into the animal’s mouth. Administer for 60-90 day cycles at the quantity indicated in the table.

The capsule is not edible. Once opened and emptied, dispose of the capsule in the organic waste.

ForhealthyJOINTS

DOG CAT

Glupacur®

Joint relief for dogs and cats of all ages.

Package sizes and dose forms

Glupacur® 30 scored tablets

Glupacur® 200 scored tablets

Glupacur® 30 stick packs

Preserves the ability to move in cats and dogs with acute joint problems.

Helps to maintain the physiological pain threshold. Protects joint cartilage.

Its unique features

• Patented formula containing highly bioavailable PGA-cur. Physiological action.

• Triple action on cartilage, inflammatory cells and oxidation.

• Efficacy demonstrated by numerous clinical trials.

• Safe and risk-free even for long-term administration.

What it contains

• PGA-cur

Patented combination of Palmitoyl-glucosamine (PGA) and curcumin (cur). It reduces the reactivity of the synovial mast cell. It releases glucosamine, which has a protective action on the joint cartilage.

• Curcumin

Neutralizes free radicals (antioxidant action).

How to use

Administer for 60-90 days at the quantity indicated in the table.

STICK PACK: the contents can be administered directly into the mouth of the animal or mixed with the food.

TABLETS: the chewable tablet can be administered directly into the animal’s mouth or crumbled into the food, taking care to ensure that it is all eaten up by the animal.

1 - 7 18 - 14 2 1

15 - 17 - 1 and ¼

18 - 21 - 1 and ½

22 - 24 - 1 and ¾

25 - 28 - 2

29 - 31 - 2 and ¼

32 - 35 - 2 and ½

36 - 39 - 2 and ¾

≥ 40 - 3

For ahealthyNERVOUSSYSTEM

DOG CAT

Alevica®

To maintain the physiological function of the nervous system.

Package sizes and dose forms

Alevica® Liquid 100 ml

Alevica® 20 scored tablets

Alevica® 40 scored tablets

Alevica® 200 scored tablets

Supports the physiological nociceptive function.

Maintains the correct pain threshold. Protects the cells of the nervous system from oxidative damage (antioxidant action).

What it contains

• PEA-q

Patented PEA (Palmitoylethanolamide) co-micronized with quercetin (q). Reduces the reactivity of the non-neuronal cells (mast cell and microglia) responsible for activating the neurons.

• Quercetin

Neutralizes free radicals and protects the nervous system against oxidative stress.

Its unique features

• Patented formula containing highly bioavailable PEA-q. Physiological action.

• Efficacy confirmed by numerous scientific studies.

• Safe and risk-free even for long-term administration.

• Formulated for fragile pets (e.g. senior pets or pets with metabolic diseases).

How to use

Administer the product at the daily quantity indicated in the table.

TABLETS: the chewable tablet can be administered directly into the animal’s mouth or crumbled into the food, taking care to ensure that it is all eaten up by the animal.

LIQUID: shake well, insert the graduated syringe in the hole in the bottle adapter, turn the bottle upside down and draw the daily quantity indicated in the table. Administer the contents of the syringe directly into the animal’s mouth or mix it with the food.

ForahealthyBRAIN

Senilife® Plus

To improve the cognitive functions and memory of senior cats and dogs, for successful brain ageing.

Package sizes and dose forms

Senilife® 30 skittle capsules

Senilife® 60 skittle capsules

For the mental health of senior cats and dogs.

Improves cognitive performance. Improves memory.

Its unique features

• Patented formula containing PEA-um (ALIA effect). Physiological action.

• Safe in senior (fragile) pets even for long-term administration.

• Efficacy demonstrated by numerous clinical trials.

• Squeezable skittle capsules easy to administer.

What it contains

• PEA-um

Bioavailable active form of PEA, it improves the short and long-term memory, both in the early and late stages of brain ageing.

• Vitamin E Neutralizes free radicals and slows down the natural cognitive decline in senior pets.

• Phosphatidylserine, Pyridoxine and DHA Promote neurotransmission.

How to use

Administer for 90-day cycles at the daily quantity indicated in the table. Open the skittle capsule as illustrated in the drawing (1) and squeeze the contents into the animal’s mouth or mix it with its ration of food (2).

Alternatively, the skittle capsules can be swallowed whole.

ForahealthySKIN

DOG CAT

Redonyl® Ultra

For healthy coat and skin.

Package sizes and dose forms

Redonyl® Ultra 50 - 60 skittle capsules

Redonyl® Ultra 150 - 60 skittle capsules

Soothes itching.

Reduces skin redness.

Improves the quality of the skin and coat.

Its unique features

• With PEA-um (ALIA effect) physiological soothing action.

• Tested and documented efficacy (international publications).

• Safe, even if used for prolonged periods.

• Squeezable skittle capsules easy to administer.

What it contains

• PEA-um (ultramicronized palmitoylethanolamide)

Maintains the physiological reactivity of skin mast cells.

• Biotin and essential fatty acids

Moisturizing and restructuring action.

How to use

Administer for 60-day cycles at the quantity indicated in the table. Open the skittle capsule as illustrated in the drawing (1) and squeeze the contents into the animal’s mouth or mix it with its food ration (2).

Alternatively, the skittle capsules can be swallowed whole.

0 - 6 1 caps/day7 - 12 2 caps/day13 - 19 - 1 caps/day 20 - 35 - 2 caps/day > 35 - 3 caps/day

ForahealthySKIN

Retopix® Mousse

To normalize skin areas affected by redness, dandruff and/ or foul-smelling greasy/oily secretions.

Package sizes and dose forms

Retopix® Mousse 150 ml

Removes surplus sebum and favors the elimination of flakes.

Reduces the bad smell in skin folds and around the ears above all.

Soothes skin redness.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Efficacy tested by clinical trials.

• Safe for long-term use even in puppies and kittens.

• Easy to apply, it is rapidly absorbed (ideal also for cats).

What it contains

• Adelmidrol

Reduces the reactivity of skin mast cells. Soothing action.

• Echinacea, Undecylenic acid and Octopirox

A sanitizing complex that helps to maintain a balanced surface microflora.

• Tapioca starch

Protects the skin from excessive moisture and helps to remove excess oil and dandruff (adsorbing action).

How to use

Apply to the dry coat two or more times a day for at least ten days. Shake and turn upside down the bottle and spray the mousse onto a hand or directly onto the pet’s coat. Apply having parted the fur with your fingers or moving your hand against the grain of the hair, and spread uniformly rubbing it in gently. Do not rinse. Retopix® Mousse can be used in combination with the other products containing Adelmidrol in the Retopix line® (Spray, Fluid, Oto). The pet should also be washed regularly with Redoderm® Shampoo. External use, avoid contact with the eyes.

ForahealthySKIN

Retopix® Fluid

To normalize the skin barrier of areas affected with redness, disepithelialization, dryness or scaling.

Package sizes and dose forms

Retopix® Fluid 10 vials of 2 ml each

Maintains an effective skin barrier function.

Moisturizing and re-epithelializing action.

Soothing and anti-redness action.

What it contains

• Adelmidrol

Reduces the reactivity of skin mast cells, thereby exerting a soothing and anti-redness action.

• Phytosphingosine

A natural component of the epidermis that favors an intact skin barrier and limits the trans-epidermal water loss.

• Hyaluronic acid and Traumatic acid

Maintain skin integrity, hydration and elasticity.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Efficacy demonstrated by scientific studies.

• Safe even for prolonged application.

• Easy application with resealable vials.

How to use

Apply a drop of fluid per cm² of skin to be treated. Massage gently for a few moments. Repeat application twice a day for at least 10 days. The vial is resealable and can be used for several applications. External use, avoid contact with the eyes.

ForahealthySKIN Retopix® Spray

To normalize areas of skin affected with redness, greasy/oily secretions and a foul smell.

Package sizes and dose forms

Retopix® Spray 100 ml

DOG CAT

Soothes

redness and skin irritation.

Helps to maintain the balance of surface microbial flora (sanitizing action).

Indicated in case of foul-smelling greasy/oily secretions.

What it contains

• Adelmidrol

Reduces the reactivity of skin mast cells (soothing and anti-redness action).

• Phytosphingosine

A natural component of the epidermis that favours an intact skin barrier and limits the transepidermal water loss.

• Triclosan, Usnic acid and Undecylenic acid

A sanitizing complex that helps to maintain a balanced skin surface microflora.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Safe for prolonged use.

• Easy to apply also to large areas.

How to use

Apply 1 spray every 10 cm² of skin. Before spraying, expose the skin by parting the fur with your thumb and index finger, or passing the hand against the grain of the hair. Rub gently for a few moments to spread the product more evenly. Repeat application 2 or 3 times a day for at least 10 days. External use, avoid contact with the eyes.

ForahealthySKIN

Redoderm® Shampoo

For gentle cleansing of the skin and coat.

Package sizes and dose forms

DOG CAT

Useful as medicated shampoo for allergic animals.

Reduces the allergen load (removes irritants, dust and pollen).

Favours a balanced skin barrier.

What it contains

• Titalin®-Zn and Ceramides Promote the integrity of the skin barrier and limit water loss.

• Echinacea purpurea, Undecylenic acid and Octopirox

A sanitizing complex that helps to maintain a balanced surface microflora.

• Normalising cleansing base Cleanses thoroughly while respecting the skin’s natural lipid composition.

Its unique features

• Safe even for frequent washes.

• Does not alter the physiological lipid composition of the skin.

• Leaves the coat shiny and silky.

SKIN AND COAT

How to use

Apply in a small quantity to the coat when wet. Rub in gently until a foam distributed uniformly across the whole body is obtained. Leave to act for at least one minute, then rinse with lukewarm water. Dry immediately. Repeat once a week as needed.

ForahealthySKIN

Repy® Gel

Improves the functional and aesthetic result of skin re-epithelialization.

Package sizes and dose forms

Repy® Gel 30 ml

Repy® Gel 75 ml

Promotes effective skin repair in case of various kinds of lesions.

Soothing and anti-redness action on injured skin.

Repellent action against licking and insects.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Safe, even if used for prolonged periods.

• With a repellent effect to preserve the wound.

What it contains

• Adelmidrol

Optimizes re-epithelialization and improves the elasticity of the skin tissue.

• Hyaluronic acid and traumatic acid

Maintain skin integrity, hydration and elasticity.

• Echinacea purpurea, Usnea barbata and snail slime

Promote the balance of surface skin microflora.

• Olio di Neem

Neem Oil gives the product a repellent action against licking and insects (e.g., flies).

How to use

Apply an adequate amount of product to the area of skin affected. Repeat the application 2 or more times a day.

Repy® Dress

Improves the functional and aesthetic result of skin re-epithelialization.

Package sizes and dose forms

Repy® Dress 10x10 cm. 5 units

DOG CAT

Promotes effective skin repair in case of various kinds of lesions. Protects the wound mechanically from external insults.

Absorbs exudates, thus promoting an ideal microenvironment.

What it contains

• Polymer gel

Absorbs exudates and does not adhere to the injured skin.

• Glycerine Protects from the overgrowth of microorganisms.

Its unique features

• Does not adhere to the wound so it is easier for the owner to monitor.

• Easy to apply even to rough areas.

• Adapts to the pet’s movements, ensuring perfect adhesion.

How to use

Remove the dressing from the sachet and peel off the transparent film. Apply to the clean wound with the gel in direct contact with the skin. Secure in place with a plaster or elastic bandage. Check the wound daily by lifting one corner of the dressing until the area to be inspected is completely visible. Replace the dressing when saturated with exudate (once a day for highly exudative wounds; every 3-7 days for dry wounds).

ForahealthyEAR

Aurìa® Drops

Normalizes the outer ear affected by redness, waxy secretions and bad odour.

Package sizes and dose forms

Aurìa® Drops 10 ml

Reduces redness and itching of the outer ear.

Reduces wax secretions.

Reduces foul smell.

Helps to maintain a balanced microbial flora of the outer ear.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Does not contain pharmacological substances

• Slightly acidic pH (5) to inhibit microbial growth.

• Suitable for skin sensitive animals.

What it contains

• Adelmidrol

Soothing and anti-reddening action.

• Phytosphingosine and traumatic acid

Maintains the epidermal barrier integrity and the proper hydration of the outer ear.

• Usnic acid and undecylenic acid Sanitising complex.

• Acetic acid

Reduces residual moisture (drying and anti-maceration action).

How to use

Apply 4-8 drops in the outer ear canal at least twice a day. Gently massage the base of the ear for a few moments to spread the product into the lower part of the outer ear canal. Use for at least 10 days. It is recommended to wash the ear canal with Aurìa® Cleansing before the treatment starts.

Aurìa® Cleansing

For the routinely ear cleaning of dogs and cats. Removes excess earwax while maintaining the natural balance of the ear.

Package sizes and dose forms

Aurìa® Cleansing 100 ml

For gentle ear cleaning in dogs and cats.

Favours the dissolution of wax and its elimination from the ear canal.

Maintains the ear's natural balance.

What it contains

• Plant based squalane Gentle ceruminolytic action. Non-ototoxic.

• Acetic acid Reduces residual moisture (drying and anti-maceration action).

• Adelmidrol Anti-irritant action.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Cleans the outer ear without irritating the epithelium.

• Suitable even for the most sensitive animals.

• Slightly acidic pH (5) to inhibit microbial growth.

• Soft dispensing nozzle to prevent scratches or injuries.

How to use

Svitare il tappino dal beccuccio. Inserire delicatamente nel canale auricolare e Remove the cap of the flush nozzle. Gently insert the nozzle in the ear canal and repeatedly squeeze the soft part of the dispenser until the ear canal is filled. Gently massage the base of the ear to evenly distribute the product. Allow the animal to shake its head to remove debris and excess earwax.

Wipe off any debris from the ear flap with a clean tissue or gauze. Use once a week, or as directed by your veterinarian. Do not use in case of suspected tympanic lesion.

Normalia®

Fast

Promotes normal gut function during acute diarrhoea.

Package sizes and dose forms

Normalia® Fast 10 openable capsules

Normalia® Fast 100 openable capsules

Rapidly improves the stool consistency.

Useful during acute diarrhoea.

Indicated in the flare-up of chronic forms.

Its unique features

• With PGA-m (ALIA effect). Physiological action.

• Dual action: maintains the physiological reactivity of the mast cells of the gut and protects the intestinal wall.

• 100% vegetable capsules that can also be used in pets with food allergies/intolerances.

What it contains

• PGA-m (micronized palmitoylglucosamine)

Highly bioavailable patented micronized compund. It maintains the physiological reactivity of the mast cells of the gut and releases glucosamine, which has a protective action (it restores the layer of mucus in the intestinal wall).

• Bentonite and Tannic Acid

Adsorbent and astringent action.

• Electrolyte complex Rehydrating action.

How to use

Administer the product for 5-10 days at the daily quantity indicated in the table.

The capsule should preferably be administered whole, placing it at the base of the tongue so that it is swallowed. Alternatively, the capsule can be opened, mixing its contents with the food.

Concomitant oral use with macrolides should be avoided.

Normalia® Extra

Promotes normal gut function during chronic diarrhoea.

Package sizes and dose forms

Normalia® Extra 30 stick packs

Normalia® Extra 60 stick packs

Normalia® Extra 30 scored tablets

Normalia® Extra 200 scored tablets

Helps to maintain normal intestinal reactivity.

Useful during chronic diarrhoea.

Essential in changes in diet (including weaning).

Normalizes gut microbiota.

What it contains

• PEA-um (ultra-micronized palmitoylethanolamide)

Active form of PEA. Reduces the reactivity of the mast cells of the gut and restores the correct permeability of the intestinal barrier.

• Bacillus subtilis

Probiotic action. Viable spore-forming bacterium resistant to high temperatures and gastric acidity.

• Bovine colostrum

Prebiotic with immunomodulatory activity. Improves the stability and biodiversity of the gut microbiota.

• Electrolyte complex

Rehydrating action.

Its unique features

• With PEA-um (ALIA effect). Physiological action.

• Safe even for prolonged administration.

• Contains no meat, meat derivatives or lactose (safe in intolerant animals).

How to use

Administer the product for at least 30 days at the quantity indicated in the table.

The contents of the sachet can be administered directly in the animal’s mouth or mixed with the food.

The chewable tablet can be administered directly in the animal’s mouth or crumbled into the food, taking care to ensure that it is all eaten up by the animal.

Body weight (kg) Stick/day Tabs/day

0 - 10 111 - 15 2 -

16 - 20 - 1

21 - 25 - 1 + ¼

26 - 30 - 1 + ½

31 - 35 - 1 + ¾

> 35 - 2

Restomyl® Gel

Relieves redness of the oral mucosa.

Package sizes and dose forms

Restomyl® Gel 30 ml

Helps to restore the integrity of oral mucosa.

Controls irritation of the gums.

Useful after dental procedures (e.g. tooth scaling and polishing).

What it contains

• Adelmidrol

Maintains the physiological reactivity of the mucosal mast cells.

• Traumatic acid

Plant-based substance with repair effect on oral mucosa.

• Phytosphingosine

Sanitizing action; it helps to maintain a balanced oral microbial flora, thus reducing the buildup of plaque.

• Hyaluronic acid

Mucoadhesive action that increases the residence time and thus the action of the other functional ingredients.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Does not contain ingredients or by-products of animal origin. Suitable for pets with food intolerances/allergies.

• Efficacy demonstrated by studies published in international journals.

How to use

Raise the lip by applying slight pressure with the tip of the applicator, taking care to ensure that the gel outlet is directed towards the mouth. Press the applicator one or more times according to the size of the pet. Due to its marked mucoadhesive properties, the gel is distributed quickly across the entire oral mucosa. Repeat the application 2-3 times a day.

Restomyl® Toothgel

Removes the plaque and protects the gums.

Package sizes and dose forms

Restomyl® Toothgel 50 ml with toothbrush

Restomyl® Toothgel 50 ml

For daily cleaning of the teeth of cats and dogs.

Anti-plaque, anti-bacterial and whitening action. Protects the oral mucosa (soothing and anti-redness action).

What it contains

• Adelmidrol

Maintains the physiological reactivity of the mucosal mast cells.

• Bromelain

Plant-based substance with a whitening action.

• Triclosan

Helps to maintain a balanced oral microbial flora, thus reducing the formation of plaque.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Designed for daily use, safe even if swallowed.

• Toothbrush specially developed not to damage the enamel (extra soft bristles) with a user-friendly grip.

How to use

Apply the gel to Restomyl® Toothbrush, brushing gently across the entire tooth surface. To ensure a good oral hygiene of cats and dogs, the teeth should be brushed once a day (AAHA* guidelines).

*AAHA (American Animal Hospital Association) Dental care guidelines for dogs and cats, JAAHA 2019

Restomyl® Dentalbones

Chewable bones for daily tooth cleaning.

Package sizes and dose forms

Restomyl® Dentalbones 482 g

Restomyl® Dentalbones Mini 340 g

These products are available only in Italy

Prevents the formation and adhesion of plaque on the teeth surface.

Slows down the buildup of tartar.

Improves breath freshness.

What it contains

• AN ProDen® (Ascophyllum nodosum)

Specific alga of the North Sea with a systemic action. through the bloodstream, its functional ingredients concentrate in the saliva where they carry out their anti-plaque action.

Its unique features

• Dual action (mechanical and systemic) against dental plaque.

• Efficacy demonstrated by published clinical trials.

• Approved by the VOHC (Veterinary Oral Health Council).

• Free of substances that mask halitosis.

How to use

Starting from the appearance of the permanent teeth, administer Restomyl® Dentalbones at the daily quantity indicated in the table. Restomyl® Dentalbones can be administered alternated with Restomyl® Supplement or Restomyl® Dentalcroc as an oral health “treat”. For toy dogs, the bone should be broken into smaller pieces. Always leave fresh water for the dog.

Restomyl® Dentalcroc

A treat for oral health and hygiene.

Package sizes and dose forms

Restomyl® Dentalcroc Dog 60 g

Restomyl® Dentalcroc Dog 150 g

Restomyl® Dentalcroc Cat 60 g

These products are available only in Italy

Prevents the formation and adhesion of plaque on the tooth surface.

Slows down the buildup of tartar.

Improves breath freshness.

What it contains

• AN ProDen® (Ascophyllum nodosum)

Specific alga of the North Sea with a systemic action. Through the circulation, its functional ingredients concentrate in the saliva where they carry out their anti-plaque action.

Its unique features

• Approved by the VOHC (Veterinary Oral Health Council).

• Extremely palatable and 100% vegetable.

• Low-calorie content.

• Free of substances that mask halitosis.

How to use

Starting from the appearance of the permanent teeth, administer Restomyl® Dentalcroc once a day in the quantities indicated in the table. Restomyl® Dentalcroc can be administered alternated with Restomyl® Supplement, as an oral health “treat”. To maintain a healthy mouth Restomyl® Dentalcroc is to be used daily for long periods of time (at least 8 months).

DOG CAT

Restomyl® Supplement

Nutritional supplement for oral health and hygiene.

Package sizes and dose forms

Restomyl® Supplement Dog 60 g

Restomyl® Supplement Cat 40 g

These products are available only in Italy

Prevents the formation of plaque.

Slows down the buildup of tartar.

Improves breath freshness.

Its unique features

• Efficacy demonstrated by numerous published clinical trials.

• Approved by the VOHC (Veterinary Oral Health Council).

• 100% vegetable.

• Free of substances that mask halitosis.

What it contains

• AN ProDen® (Ascophyllum nodosum)

Specific alga of the North Sea with a systemic action. Through the circulation, its functional ingredients concentrate in the saliva where they carry out their anti-plaque action.

How to use

Starting from the appearance of the permanent teeth, administer Restomyl® Supplement, mixed with food (wet or dry), at the daily quantities indicated in the table. To be used daily for long periods. The results are generally obtained during the 3rd week of use.

Restomyl® Supplement can be administered alternated with Restomyl® Dentalcroc.

Body weight (kg) Supplement Dog Supplement Cat 0 - 10 ½ measure 1 measure 11 - 25 1 measure / > 25 2 measures /

Oculvet® Gel

Protects the ocular surface in case of dry eye.

Package sizes and dose forms

Oculvet® Gel 10 ml

Lubricant and humectant action.

Relieves the symptoms of dry eye.

Maintains the integrity of the cornea surface.

Its unique features

• Acts on all three layers (lipid, water and mucin) of the tear film.

• Long-lasting effect.

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Soft applicator nozzle.

What it contains

• MCT (medium-chain triglycerides)

Reintegrate the lipid layer by limiting evaporation (less frequent applications).

• Hyaluronic acid & Carbomer

Mucoadhesive polymer gel with a long-lasting moisturizing effect.

• Adelmidrol

Increases the endogenous levels of PEA, a natural component of the eye (its reduction causes dry eyes).

How to use

Pull the lower eyelid down gently and apply a small quantity of gel in the conjunctival sac at least twice a day, taking care not to touch the eye with the applicator nozzle. Close the eyelid and rub gently to distribute the gel uniformly across the eye surface. Before you apply the product, remove any secretions from the area using a sterile wipe (e.g. Oculvet® Wipes).

Oculvet® Drops

Gives relief to red eyes.

Package sizes and dose forms

Oculvet® Drops 10 ml

Soothes the redness of eye tissues.

Useful against pollen, dust, wind, etc.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Free of side effects; ideal also for repeated applications.

• Can be used together with any medicinal product.

What it contains

• Adelmidrol

Completely physiological soothing and anti-redness action.

• Hyaluronic acid Lubricant action.

How to use

Pull the lower eyelid down gently and instil 1 or 2 drops in the conjunctival sac at least twice a day, taking care not to touch the eye with the dropper. Before you apply the product, remove any secretions from the area using a sterile wipe (e.g. Oculvet® Wipes).

Oculvet® Wipes

For cleansing the periocular area (e.g. eyelids, eyelashes).

Package sizes and dose forms

Oculvet® Wipes, 14 sterile wipes

To remove eye discharge also before applying eye drops or ophthalmic gels.

Useful for minimizing tear staining caused by excessive tearing.

Indicated to remove irritants, dust and pollen.

To clean around the eyes before and after surgery and in case of blepharitis/ conjunctivitis.

What it contains

• Adelmidrol

Completely physiological soothing and anti-redness action.

• Complex of plant extracts

Emollient and cleansing action. Helps to maintain a good periocular cleanliness.

• Hyaluronic acid

Humectant and moisturizing action.

Its unique features

• Contains Adelmidrol (ALIA mechanism). Physiological action.

• Soft TNT wipes (not harmful for the cornea).

• Sterile, ideal for use before and after surgery.

EYES

How to use

Wash your hands and remove the wipe from the sachet. Cleanse the periocular area gently. For a better soothing action, the sachet can be kept closed in the refrigerator for half an hour before putting the wipe in position for a few minutes.

Nefrys

To maintain a healthy upper urinary tract.

Package sizes and dose forms

Nefrys® 100 ml with dosing syringe

Helps to maintain the physiological balance of the kidney.

Protects the kidney against toxic substances.

Reduces oxidative stress.

What it contains

• PEA-um (ultra-micronized palmitoylethanolamide)

Active form of PEA. Maintains the correct reactivity of kidney mast cells.

• Silymarin

Flavonoid extract from Milk thistle (Silybum marianum) with an antioxidant function.

• Chitosan and Calcium carbonate

Help to maintain the intestinal physiological levels of phosphate and products of protein digestion (e.g., nitrogenous waste).

Its unique features

• With PEA-um + Silymarin (patented combination). Physiological action.

• Contains no meat or meat derivatives.

• Safe also for prolonged administration, it presents no contraindications or side effects.

How to use

Administer twice a day the quantity indicated in the table at mealtime. Shake the bottle well, insert the graduated syringe in the hole and draw the preselected quantity indicated in the table. Administer the contents of the syringe directly into the animal’s mouth or mix it with the food. * To be administered twice a day

Urys

For a healthy lower urinary tract.

Package sizes and dose forms

Urys® Liquid 60 ml with dosing syringe

Urys® Caps 30 skittle capsules

Helps to maintain the physical balance of the bladder.

Promotes the barrier function of the urothelium (inner lining of the lower urinary tract). Protects the lower urinary tract from oxidative stress.

What it contains

• PGA-m (micronized palmitoyl-glucosamine) Reduces the reactivity of bladder mast cells. It releases glucosamine, a natural component of the protective layer of the bladder urothelium.

• Hesperidin Flavonoid extracted from bitter orange (Citrus aurantium) with a high antioxidant activity.

Its unique features

• With PGA-m (ALIA effect). Physiological action.

• Can be used for long periods of time (safe).

• Two dose forms for easy administration (squeeze skittle capsules and liquid).

• Palatable and easy to administer to cats.

How to use

Administer the product at the daily quantity indicated in the table. CAPS: open the skittle capsule as illustrated in the drawing (1) and squeeze its contents into the animal’s mouth or mix it with its ration of food (2). Alternatively, the skittle capsules can be swallowed whole.

LIQUID: shake well, insert the graduated syringe in the hole in the bottle adapter, turn the bottle upside down and draw the daily quantity indicated in the table. Administer the contents of the syringe directly into the animal’s mouth or mix it with the food.

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