Asia PharMed & HealthCare Thailand Digital Issue No.2

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ISSUE NO.2 www.ipriasia.com

Medical Technology - Equipment & Device - Pharmaceutical - Manufacturing - Health Care & Technology Information

Thailand’s Medical Medical Thailand’s Sector Resilient Resilient in in the the Sector Face of of the the Pandemic Pandemic Face Centrifuges Selection for Efficient Separations How How Artificial Artificial Intelligence Intelligence is is Reshaping Reshaping Medical Medical Billing Billing && Insurance Insurance

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PACKAGING FOOD PROCESSING INGREDIENT & CHEMICALS SUPPLY CHAIN & LOGISTICS ASIA UPDATE

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Editor’s note ADDRESS IPRI Co.,Ltd. 58/2 Soi Phrom Sri, Sukhumvit Rd., Khlong Tun Nuea, Wattana, Bangkok 10110 Thailand Tel: +66 (0) 2392 2011 Fax: +66 (0) 2392 2012 Website: www.ipriasia.com MANAGEMENT Publisher Wannee Sananwatananont : wannee@ipriasia.com MEDIA DIRECTOR Laverne S.Taypin : lawant@ipriasia.com ADMINISTRATION / DIGITAL SUBSCRIPTION Rawiphan Promgam : rawiphan@ipriasia.com DIGTAL TEAM / PRODUCTION Wiratchada Sukkhathon : pure@ipriasia.com Watcharida Sukkhathon : preem@ipriasia.com

As the world faces challenges due to Covid-19, which has disrupted lifestyles of people regardless of their race or skin color, all across the world. And as the digital technologies, the upcoming 5G network have provided people with fast and broad access to information, helping to connect people across borders. increasing production efficiency in the manufacturing sectors, thanks to the full speed and unlimited connectivity, making the world a smaller place like one could never have imagined before. This edition of Digital Magazine for industrial sector of Pharmaceutical, Medical Equipment & HealthCare that you are now reading the latest updates on modern technologies for the manufacturing industry of Pharmaceutical, Medical Equipment & HealthCare so that everyone can access latest technologies from the manufacturers and for the manufacturing industry instantly and with efficiency. It also allows you to access to information in digital format enable you can easily forward and share the information to those that are relevant. I hope that our readers will benefit from Asia PharMed & HealthCare Thailand Digital issue. As for any of the latest developments on new technologies that you would like to share, kindly send to us at editor@ipriasia.com. We are more than happy to be the medium for sharing your news.

Lavene S.Taypin

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CONTENTS Manufacturing

6 Thailand’s Medical Sector Resilient 9 in the Face of the Pandemic Reliable operator guidance for size changeover

INDUSTRY ASSOCIATION

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MEDICAL TECHNOLOGY

2nd MEDTEC Innovation Award, Mizuho Medical Industry Winner

12 13 NSTDA and partners present innovations to frontline 14 health hospitals to fight against COVID-19 NSTDA and Thammasat University Hospital to work on digital healthcare NSTDA launches Cannabis Analytical Testing Laboratory

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Equipment & Device Centrifuges Selection for Efficient Separations

Healthcare & Technology UN agencies warn economic impact of COVID-19 and worsening inequalities will fuel malnutrition for billions in Asia and the Pacific - Child and maternal diets particularly vulnerable

20 State Of Retail Tech H2’20 Investment & Sector 21 Report: Trends To Watch How Artificial Intelligence Is Reshaping Medical Billing & Insurance

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SPECIAL ARTICLE

22 Scientists Without Borders 24 The ABCs of CBD Lots of New German Medications 25 in 2020 Show preview

26 Intercare asia 2021

Thailand news

28 Coronavirus disease 2019


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Manufacturing by SIKO

Reliable operator guidance for size changeover When companies need packaging machines for their products – whether it’s for coffee capsules, cough sweets, batteries or plasters – the most important aspect of the investment is to find the most flexible solution that can handle a wide range of package sizes and formats. However, this requires intelligent size change over in order to be able to provide such flexibility. Electronic position indicators from SIKO simplify the changeover process on SOMIC packaging machines and ensure simple operator guidance and greater process reliability. SOMIC is well known for innovative solutions in end-of-line packaging machines, i.e. for secondary and tertiary packaging. These include wraparound packers, tray packers or tray lid packers as well as machines for display packaging presented to customers in the supermarket. Here, either the wraparound carton has a typical tear perforation or, in the tray lid version, the lid is removed and the product is presented in the tray. SOMIC machines are characterized primarily by the fact that the respective carton is folded around the product in its primary packaging and not inserted into a pre-folded carton via picker, as is the case with other manufacturers. As a rule, a packaging machine consists of a product infeed, through which the individual products are fed into a so-called collection group. Typically, this is a compartment file, which groups the products in the way they are to be placed in the box later. Depending on whether it is a one-piece or two-piece package, a flat carton blank is transported from one or two carton magazines until the grouped product can be pushed onto the flat blank. This is finally folded around the product protected by the folding head, which means that the product is handled very gently. In the next station, the product is then lidded or individually sealed, depending on whether it is a wraparound or lid tray machine.

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SIKO position indicators: clear and easy to read SIKO mechanical position indicators, specialist in industrial measuring and drive technology, are installed in all SOMIC machines for possible size changeovers to different product or packaging sizes. “We have already enjoyed many years of good cooperation with SIKO in the field of mechanical position indicators”, emphasizes Dr. Johann Härtl, Head of Construction at SOMIC. “For about nine years now, we have also been using the electronic, bus-compatible SIKO displays, first the AP04 and now the successor model AP05. They are very compact, easy to integrate into the machine control system and very user-friendly in terms of readability and clarity.” Adjustments on SOMIC customer machines are very different: “There are machines with only one format setting, so-called Highrunner lines. Other customers, on the other hand, have up to 20 or 30 formats on the lines and make full use of the flexibility. Some even produce wraparound and tray packaging on a single machine, where a wide variety of products need to be packaged. SOMIC covers a large product range in the food sector, but also in non-food, pharmaceuticals and cosmetics. Dr. Johann Härtl commented: “Anything in a supermarket in a tray pack could have been packed in a SOMIC machine!”


Process reliability with red/green system The advantages of monitored size changeover, as made possible by the integration of the electronic SIKO position indicators, are faster changeover times, ergonomic operation and high process reliability. The operator simply selects the respective format, which is stored as a recipe in the machine control system, and the machine control system sends the new set values to the displays to be adjusted. The backlit LCD displays are easy to read and also feature green and red status LEDs. When the correct value is reached by turning a crank, the LED changes to green: Position reached. Otherwise the LED will continue to light up red and readjustment is necessary. In addition, arrows also conveniently indicate the direction in which adjustment is required. As the communication interface of the SIKO position indicators in the machine control always provides the current position information, it is effectively ruled out that incorrect settings could lead to quality

problems or even damage to machine parts when the machine is restarted. Adjustment with electronic displays is much more efficient, especially on machines with many adjustment points and frequent changes. The machine has stored all default values; target positions no longer have to be manually selected from format lists.

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Manufacturing by SIKO

Monitored size changeover and “quick change principle” With SOMIC, the factors of time savings and efficiency are not only guaranteed by electronic SIKO position indicators when changing formats, but also by the “Quick Change Principle”. Here, format parts are changed in their entirety in the machine. All that is needed to achieve this is a quickrelease fastener, which means that no further tools are required. Taken together (adjustment via electronic position indicator and Quick Change principle), SOMIC packaging machines can be converted to new dimensions much more efficiently. Dr. Johann Härtl knows that the customers’ response to the electronically monitored size changeover is very positive: “The AP05 is optional; mechanical SIKO meters are installed as standard. However, the trend is clearly moving towards electronically monitored indicators, especially since around 90 to 95 percent of our machines require size changeovers.”Approximately 50 percent of customers already use the electronic version, with SOMIC expecting a further increase here. Dr. Johann Härtl: “The digitalization of machines continues to increase. And the AP05 is one more sensor that helps me to record machine data. So I know, for example, when I have driven which batch with which setting and can save the data.”

Portrait of Dr. Johann Härtl, Head of Construction at SOMIC ©SOMIC Next step: Full automation The next expansion step would be the full automation of size changeover via actuators. The first concepts are already being tested here at SOMIC, as the customer’s desire for increasing machine flexibility while simultaneously maintaining high process reliability is strong, in order to be able to map as many different formats as cost-effectively as possible. The more adjustment points there are and the more often the formats have to be changed, the more interesting fully automated adjustment becomes. SOMIC is already in discussion with SIKO regarding fully automated actuators. “We are happy to provide support for further developments and new projects”, emphasizes Moritz Müller, PositionLine Product Manager at SIKO. “This includes, for example, the integration of IO-Link interfaces to simplify integration into the machine control system or full automation via our add-on-compatible compact actuators.” More information : www.siko-global.com/

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Manufacturing

by Thailand Board of Investment

Thailand’s Medical Sector Resilient in the Face of the Pandemic

The response of Thailand to the global COVID-19 pandemic has been one of the world’s most successful. The extremely low number of infections and fatality rate has won praise from the World Health Organisation, the United Nations and experts around the globe. The Global COVID-19 Recovery Index has consistently ranked Thailand in the top five of out of 184 countries in the effectiveness of its battle against the virus, underlining the resilience of its medical infrastructure. This will come as no surprise to those familiar with the medical sector of Southeast Asia’s second-largest economy. It has built a reputation as a leading medical tourism destination, on a foundation of world-class medical facilities and personnel, combined with outstanding cost performance. The global pandemic has impacted medical tourism, but hasn’t stopped Thailand innovating in healthcare.

according to the Thailand Board of Investment (BOI), which introduced a range of measures this year to accelerate investment in the medical sector. These applications, from both global and domestic investors, were predominantly for the manufacturing of medical equipment and supplies to support the rapid response to COVID-19, We have approved more than 80 percent of the projects in order to respond to the situation, while paving the way for Thailand’s longer-term development as a manufacturing hub for medical devices and suppliessaid BOI Secretary General Ms Duangjai Asawachintachit.The battle against COVID19 is only intensifying investor interest in the country’s already advanced medical infrastructure. Along with cutting-edge research laboratories and medical device manufacturing, there are more than 60 hospitals certified by the Joint Commission International (JCI), the leading global accreditation body for healthcare facility standards, and more than 60,000 licensed doctors in Thailand.

Resilient innovation and investment The country is becoming an increasingly important destination for investment in medical tech and services, in line with the government’s Thailand 4.0 concept of a dynamic, high-value and sustainable economy that delivers better quality of life for all. More than 50 applications for investments in projects totalling $400 million dollars were submitted in the first half of 2020,

Thailand has taken gradual steps to reopen for medical tourism, allowing limited numbers of people to enter the country for treatment since the end of July 2020. Rigorous protocols are in place for medical tourists and the up to three people who can accompany them, including proof of negative testing for COVID-19 issued no more than 72 hours before departure, repeated tests once in-country, 14 days hospital quarantine and other anti-infections measures.

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Manufacturing

by Thailand Board of Investment Transforming medicine digitally Bangkok’s Bumrungrad International Hospital is one of the facilities currently permitted to accept overseas patients. The JCI-accredited hospital launched telemedicine consultations in late 2019, expanding those offerings with its Bumrungrad @ Home service in March 2020, when the pandemic made it more difficult for patients to visit doctors. “Because care does not end at the hospital, the key advantage for patients is to get the continuous standard of care provided in the hospital, with more convenience. You can see your doctor, undergo laboratory tests, receive medications, and access many services without having to travel to the hospital,” explained Ms Artirat Charukitpipat, CEO of Bumrungrad. This will come as no surprise to those familiar with the medical sector of Southeast Asia’s secondlargest economy. It has built a reputation as a leading medical tourism destination, on a foundation of world-class medical facilities and personnel, combined with outstanding cost performance. The global pandemic has impacted medical tourism, but hasn’t stopped Thailand innovating in healthcare. “With a patient-centric design, the service is easy to use even for elderly people who are unfamiliar with technology,” added Ms Charukitpipat. As well as patients in Thailand, those from across Asia, the Middle East and the USA have also utilised it. Bumrungrad is planning to expand its telemedicine service even after the pandemic passes, employing the latest technology and treatments to deliver the best care to patients wherever they are. The pandemic is accelerating shifts that were already in motion, and Doctor A to Z - a medtech start-up launched in 2018 by Dr Anucha Panoi and Ms Kannika Jampaphan and Mr Teerayut Yoonun, who have decades of experience in medicine - is finding its virtual care platform in ever more demand. Through its mobile app, patients can seamlessly connect with specialist doctors from anywhere for consultations on cancer, gastrointestinal issues, orthopaedics, dentistry, mental health, rehabilitation and numerous other conditions. As an online medical assistance, the platform facilitates the easy exchange of information between patients and healthcare professionals. It also allows for access to pharmacies, hospitals, insurance services and other medical assistance services, via its one-stop ecosystem, in Thai or English.

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The company has also teamed up with Thailand’s Department of Consular Affairs to provide medical consultations for Thais living overseas, allowing them to connect with worldclass doctors from home even during the pandemic. Furthermore, the platform facilitates medical tourist from around the world for treatment in Thailand across more than 30 JCI hospitals. “The hundreds of specialist doctors available in Thailand through the platform are our greatest resource,” said Dr Panoi, who added that Doctor A to Z is looking at further expanding its international presence. Doctor A to Z is backed by the BOI, giving it tax breaks and other incentives. The company is also able to apply for Smart Visas for key employees, start-up entrepreneurs and invetors, allowing them to work and stay in the country for up to four years. Such support is just one of the reasons more entrepreneurs and investors are focusing on Thailand. The global pandemic has created not only challenges for every country, but also opportunity, and Thailand is drawing on its resilience to face this unprecedented situation. The country is adapting to the new environment by utilising digital technology to expand and improve telemedicine services, creating a more welcoming business environment to drive medical investment and innovation, and taking its advanced healthcare infrastructure to the next level. Learn more about Thailand Board of Investment : https://reut.rs/3ppRY37


MEDICAL TECHNOLOGY BY MEDTEC JAPAN

2nd MEDTEC Innovation Award, Mizuho Medical Industry Winner The 2nd “ MEDTEC Innovation Award “ (sponsored by UBM Canon), which recognizes Japanese companies that have achieved outstanding results in the manufacture and design of medical devices, has been selected as the “ Near Infrared Fluorescent Color Camera System “ by Mizuho Medical Industry Co., Ltd. After the decision, the award ceremony was held at the MEDTEC Japan venue at Tokyo Big Sight on Wednesday, 24th. This Innovation Award aims to further revitalize the development of medical devices by commending companies that are actively challenging the development of the world’s first medical devices originating in Japan and by arousing public opinion to support them. Although Mizuho Medical Industry is a manufacturer of operating room equipment, it was highly evaluated for its ability to capture the needs of cardiovascular clinicians and to commercialize high technology in collaboration with companies in different industries. Grand Prize was awarded the Mizuho Medical Industry of the product , the company is applying the seeds technology of the needs SANYO Semiconductor Co., Ltd. from Takayuki Sato professor of Kochi University School of Medicine cardiovascular control studies, the world’s first near-infrared fluorescence and color image It has been commercialized as a surgical support system that can be photographed at the same time. “It is an excellent technology in the world, but it was highly evaluated for its cooperation with different industries,” said Tsuguo Takegami (Deputy Director and Professor of NICHe, Tohoku University) on behalf of the judges at the award ceremony. Praised. Mr. Yoshiyuki Myonaka, the chairman of the judging committee of this award (representative of the committee for the sake of life in Japan, director of the National Cardiovascular Research Center R & D Infrastructure Center) also said, “Although it was originally a medical device manufacturer, It is wonderful that he led the development of cutting-edge technology from different industries (Sanyo Semiconductor) in the medical device field. “

Mizuho Medical Industry Marketing Development Promotion Department receives a certificate from Jury Chairman Masaki Kitajima (Representative of Japan Medical Engineering Manufacturing Commons: left photo) and award trophy from Vice Jury Chairman Christopher Eve (UBM Japan President: Photo right) Mr. Ichiro Kitani (center of the photo).

In addition, compared to last year, the tendency of applicant companies this year is that “there were many efforts for collaboration with different industries and joint development / commercialization with clinical sites” and “business development with a view to overseas expansion”. “The number of companies doing this has increased,” said Mr. Myonaka, who told “MEDTEC Medical Devices” magazine after the award ceremony that “the national (growth strategy in the medical device field) policy has begun to permeate.” The “ MEDTEC Innovation Award “ has reached its second year this year, and Masahiko Miyata, President of Asahi Intecc Co., Ltd., the winner of the 1st Innovation Award, has joined the jury this time. “ That was awarded the grand prize this has led to the next opportunity .” There is also president of stories with, from the jury were received many future expectations for the awards won, Inc., including the grand prize. Source : www.medtecjapan.com/ja/news/2013/04/24/806 DIGITAL ISSUE NO.02 : MARCH 2021

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INDUSTRY ASSOCIATION By National Science and Technology Development Agency (NSTDA)

NSTDA and Thammasat University Hospital to work on digital healthcare

NSTDA and Thammasat University Hospital have signed an MOU for the R&D collaboration on digital healthcare to support the transition into smart hospital. The partnership was announced by NSTDA President Dr. Narong Sirilertworakul and Hospital Director Dr. Pharuhat Tor-Udom.

In his remarks, Dr. Narong gave examples of NSTDA innovation and solutions in healthcare sector that developed by Assistive Technology and Medical Devices Center (A-MED), MTEC and NECTEC, some of which have been developed or tested in collaboration with Thammasat University Hospital. These innovations include a dental scanner DentiiScan, a digital chest radiography system BodiiRay S, a positioning device setting patients in a beach chair position for shoulder surgery and a multi-people temperature screening system μ Therm. According to Dr. Pharuhat, the 741-bed hospital provides outpatient, inpatient and emergency services in all areas and

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accepts referrals from other hospitals. In 2020, the hospital had an average 5,392 outpatient visits/day and 71% inpatient bed occupancy. NSTDA and the hospital are currently developing a prototype device to track the locations of medical devices within the hospital building using an Indoor Localization System with Bluetooth Low Energy (UNAI) platform and monitor energy consumption in order to design medical device utilization management system. The two parties plan to add more projects into the collaboration and expect to bring these innovative solutions to members of the University Hospital Network (UHosNet) and eventually to market.


NSTDA launches Cannabis Analytical Testing Laboratory

NSTDA Characterization and Testing Center (NCTC) announced a launch of Cannabis Analytical Testing Laboratory and signed an agreement with Play La Ploen Herbal Center Community Enterprise located in Buriram province to perform cannabis testing for the enterprise to ensure their products meeting international standards. Dr. Natthaphon Wuttiphan, NCTC Director revealed that Cannabis Analytical Testing Laboratory provides complete testing services on cannabis and hemp to support the medical and related industry to ensure product quality and safety. The laboratory is internationally accredited by ISO/ IEC17025. The range of services provided include potency test (amount of cannabinoid present in products), terpene profiling and safety tests (heavy metals, pesticides, residual solvents, mycotoxins and microorganism).

Play La Ploen Herbal Center Community Enterprise currently grows cannabis plants in a greenhouse to produce cannabis with consistent quality for medical purposes. The partnership formed with NSTDA will help enhance the quality and safety of products produced by the enterprise. Ms. Sasikarn Lorjiropas, President of Play La Ploen Herbal Center Community Enterprise further explained that Play La Ploen plans to serve as an intermediary between farmers and other community enterprises and NCTC to promote quality control and assurance of cannabis products.

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INDUSTRY ASSOCIATION By National Science and Technology Development Agency (NSTDA)

NSTDA and partners present heath innovations to frontline hospitals to fight against COVID-19

Since the COVID-19 outbreak emerged in December 2019, NSTDA has been developing innovative healthcare solutions to fight against the disease. As the latest outbreak erupted in December 2020, NSTDA and its partners have presented the following medical devices and healthcare products developed by NSTDA research team to a number of hospitals and health facilities. Girm Zaber UV-C Sterilizer is a sterilizing device utilizing UVC at 254 nm wavelength to kill germs present in the air and on object surfaces. The device disinfects rooms and equipment, killing fungi, bacteria and viruses, including COVID-19, within 5-15 minutes. In addition to save time, labor and disinfectant costs, Girm Zaber help minimize the workers’ risk of exposure to coronavirus. Its performance was tested by the Institute of Biotechnology and Genetic Engineering, Chulalongkorn University. The product meets TIS 1955/

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EN 55015 standard as tested by Electrical and Electronic Products Testing Centre (PTEC). Girm Zaber Robot was developed by the National Security and Dual-Use Technology Center, one of NSDTDA’s focus centers. NSTDA and BMF Innotech, the Girm Zaber licensee, donated six Girm Zaber Stations to Rayong Hospital, Chulalongkorn University Laboratory Animal Center and Samut Sakhon Public Health Office. Benzion is a disinfectant effective against pathogenic bacteria and viruses, including COVID-19. The product is based on an innovation co-developed by NANOTEC and BIOTEC, in which chelating and stabilizing agents were added to enhance the antimicrobial activity of zinc ion. Unisil Group, a licensee of zinc ion technology, gave 64 gallons of Benzion to Rayong Hospital, Public Health Office of Samut Sakhon province, Mae Ramad Hospital and Umphang Hospital in Tak province.


Safie Plus is a four-ply medical face mask coated with hydroxyapatite-titanium dioxide composites offering 99% protection from PM2.5 (tested by TÜV SÜD), 99% viral filtration efficiency (tested by Nelson Labs) and anti-H1N1 (tested by Mahidol University). Safie Plus was co-developed by MTEC and Assistive Technology and Medical Devices Center (A-MED), one of NSTDA’s focus centers. Safie Plus masks are produced by an ISO 13485 certified manufacturer. A total of 160,000 Safie Plus masks were donated to Samut Sakhon Public Health Office, Mae Ramad Hospital and Umphang Hospital in Tak province, Banphaeo General Hospital in Samut Sakhon province, Sonkhla Hospital and Hat Yai Hospital in Songkhla province, King Prajadhipok Memorial Hospital in Chanthaburi province and Rayong Hospital.

BodiiRay S is a digital chest radiography system developed by A-MED. BodiiRay S comes with RadiiView software for image processing and viewing and is linked to Picture Archiving and Communication System (PACS). A unit of BodiiRay S was presented to a field hospital in Samut Sakhon province. Source:https://www.nstda.or.th/en/news-related-to-research/ research-news-year-2021/1231-nstda-and-partners-presentheath-innovations-to-frontline-hospitals-to-fight-againstcovid-20.html

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Equipment & Device By OHAUS INDOCHINA LIMITED

Centrifuges Selection for Efficient Separations Centrifuges are the basic equipment tool in the laboratory. It use for separates solids-liquids or liquids-liquids base on different specific gravity or density properties of substances. The separation is encouraged by centrifugal force that lets the substances move outward in the radial direction. Main factors of centrifuge are Speed and g Force, both factors are the basic to be consider before selection and use the centrifuge. Besides, temperature factor had effect to temperaturesensitive sample that we can select the refrigerated centrifuge (down to -20 C) model to control chamber temperature during spinning.

Rotor type that holds the sample tubes had also important to consider. There are fix angle rotor and swing out rotor that varied size of volume from 1.5ml up to 750 ml or higher. Rotor Type are effect to speed set up limit in centrifuge. Therefore, centrifuges selection for efficient separations firstly we need to know the volume of sample that we use and max speed for spinning. Secondly, we consider rotor type that can support for both volume and speed and the last step have to look model of centrifuge (can select room temperature centrifuge or refrigerated centrifuge) that support with rotor type, maximum speed and sample. Then we can confident our separation works get the good results.

Centrifuge

Fixed Angle Rotor

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Swing Out Rotor


Healthcare & Technology By WHO Thailand

UN agencies warn economic impact of COVID-19 and worsening inequalities will fuel malnutrition for billions in Asia and the Pacific - Child and maternal diets particularly vulnerable

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Healthcare & Technology By WHO Thailand

The economic impact of COVID-19 on the world’s most populous region is threatening to further undermine efforts to improve diets and nutrition of nearly two billion people in Asia and the Pacific who were already unable to afford healthy diets prior to the pandemic, says a new report published today by four specialized agencies of the United Nations. The report found that 1.9 billion people were unable to afford a healthy diet, even before the COVID-19 outbreak and the damage it has since caused to economies and individual livelihoods. Due to higher prices for fruits, vegetables and dairy products, it has become nearly impossible for poor people in Asia and the Pacific to achieve healthy diets, the affordability of which is critical to ensure food security and nutrition for all – and for mothers and children in particular. Food prices and available incomes govern household decisions on food and dietary intake. But the outbreak of COVID-19 and a lack of decent work opportunities in many parts of the region, alongside significant uncertainty of food systems and markets, has led to a worsening of inequality, as poorer families with dwindling incomes further alter their diets to choose cheaper, less nutritious foods. Making nutritious foods affordable and accessible More than 350 million people in the Asia and the Pacific were undernourished in 2019, or roughly half of the global total. Across the region, an estimated 74.5 million children under 5 years of age were stunted (too short for their age) and 31.5 million suffered from wasting (too thin for height). The majority of these children live in Southern Asia with nearly 56 million stunted and more than 25 million wasted. At the same time, overweight and obesity has increased rapidly, especially in South-Eastern Asia and the Pacific, with an estimated 14.5 million children under 5, being overweight or obese. Poor diets and inadequate nutritional intake is an ongoing problem. The cost of a healthy diet is significantly higher than that of a diet that provides sufficient calories but lacks in nutritional value, showing significant gaps in the food system to deliver nutritious options to all at an affordable price. These costs are even greater for women and children, given their added nutritional needs.

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The report calls for a transformation of food systems in Asia and the Pacific, with an aim to increase the affordability of, and families’ access to, nutritious, safe, and sustainable diets. Nutritious and healthy diets need to be accessible to everyone, everywhere. To ensure that happens, the report recommends integrated approaches and policies are needed. These steps are vital to overcome unaffordability issues, and also to ensure healthy maternal and child diets. Improving maternal and child diets requires strengthening vital systems Nutrition is vitally important throughout a person’s life. The impact of a poor diet is most severe in the first 1000 days, from pregnancy to when a child reaches the age of 2. Young children, especially when they start eating their “first foods” at 6 months, have high nutritional requirements to grow well and every bite counts. Mainstreaming nutrition-focused behaviour change campaigns throughout these systems should lead to greater knowledge uptake and sustainability of behaviours helping people to achieve healthy diets. Education on what constitutes a healthy diet and how to create hygienic environments at home, in schools and in the community, together with investment in girl’s education and infrastructure that underlies good water, sanitation and hygiene practices, are critical. Therefore, providing a nutritious, safe, affordable and sustainable diet for all requires coordinating with partners in the Food, Water and Sanitation, Health, Social Protection and Education systems, to collectively create an enabling environment. Greater attention is also needed to operationalize national policies and plans to improve the delivery of health services for maternal and child diets and good nutrition outcomes. Services to improve the diets of mothers and young children should be prioritized as part of the essential package of health services needed to address undernutrition, overweight and obesity and to achieve universal health coverage. In the meantime, social protection efforts can protect and stabilize incomes and improve access to healthy diets during disasters and crises. At least nine governments in Asia and Pacific have established a targeted mother and child COVID-19 component in their social protection systems. However,


more data collection and analysis are needed to document the effectiveness of social protection in improving maternal and child diets in the region.

The report also calls for action within the private sector, as it has an important role to play in supporting the transformation of the food system and its value chains for achieving healthy diets.

Bringing everyone to the table Food systems play a critical role in achieving food and nutrition security for all. A sustainable and nutrition-sensitive food system is essential to produce diverse and nutritious foods for healthy diets. Improved efficiency and productivity of value chains can reduce the costs of essential foods to make them more affordable. These actions are needed now more than ever because the face of malnutrition is changing in Asia and the Pacific, with highly processed and inexpensive foods readily available throughout the region. These foods are often packed with sugar and unhealthy fats and lack the vitamins and minerals required for growth and development. Consumption of these foods increases the risk of obesity, diabetes and cardiovascular disease. Governments need to invest in nutrition and food safety in fresh and street food markets to promote healthy diets. Regulation of sales and marketing of food for consumers, especially children, is important to curb overweight, obesity and related diseases and illness.

Leveraging these systems, in a coordinated fashion that expands the opportunities to address barriers to accessing and consuming healthy diets, will help countries and the people of Asia and the Pacific recover faster from the economic impact of COVID-19, and be better prepared for future crises. The report, ‘Asia and the Pacific Regional Overview of Food Security and Nutrition 2020: Maternal and Child Diets at the Heart of Improving Nutrition’ launched today in Bangkok, is jointly published by the Food and Agriculture Organization of the United Nations, the United Nations Children’s Fund, the World Food Programme and the World Health Organization. Source : https://www.who.int/southeastasia/news/detail/20-01-2021-un -agencies-warn-economic-impact-of-covid-19-and-worseninginequalities-will-fuel-malnutrition-for-billions-in-asia-and-the-pacific--child-and-maternal-diets-particularly-vulnerable

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MEDICAL TECHNOLOGY BY CB Insights

How Artificial Intelligence Is Reshaping Medical Billing & Insurance

Artificial intelligence is helping healthcare providers save money and improve efficiency in billing and insurance. From speech recognition for clinical documentation to machine learning for data extraction, here’s how the tech is improving medical financing. Manual, repetitive tasks in billing and insurance processes can be exasperating and costly for providers. Artificial intelligence could help. In recent years, AI tech has gained popularity as a solution to combat care team burnout and cut operational costs -improve ments made more necessary by the financial and mental stress caused by Covid-19. For example, natural language processing (NLP) can automatically translate physician notes into billable medical codes, while researchers are developing algorithms that use historical data to predict the likelihood that a claim will be denied. AI in medical insurance is gaining media attention as health teams continue to realize its potential to improve billing and insurance tasks.

Below, we explore 3 ways AI is transforming the healthcare billing and insurance cycle: AI for prior authorization, NLP for automated medical coding, and AI-powered robotic process automation (RPA) for claims management.

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KEY TAKEAWAYS Artificial intelligence can help optimize backend systems. Administrative workflows, such as filing claims or medical coding, are one of the leading costs for healthcare systems and causes of burnout. AI can help automate and optimize these workstreams. Recent advancements in NLP are streamlining the billing and insurance cycle. Significant progress in inter preting medical documentation has been made with language models from Google and OpenAI. Healthcarefocused open source NLP tools have also been released for developers such as Amazon Comprehend Medical and Google’s Healthcare Natural Language API. AI solutions in administrative automation will largely depend on electronic health record (EHR) data. Medical coding solutions use EHR notes to translate health services into billing codes, and AI-powered RPA platforms can extract data from EHRs to populate claims forms.


State Of Retail Tech H2’20 Report: Investment & Sector Trends To Watch Our retail tech report takes a data-driven look at global retail technology investment trends and top deals, highlighting areas of interest across the retail landscape. The State of Retail Tech report takes a data-driven look at global retail technology investment trends and top deals, featuring insights from our emerging tech insights platform. The data in this report covers H2’20 (as of November 30). In a tumultuous year for retail, total financing and deals in retail tech in 2020 will still likely trail 2019 totals, by about 5% in funding and 8% in deals. But urgent needs to make stores safer, more efficient, and more productive, as well as continued investment in e-commerce infrastructure, drove significant growth in funding across key sectors in the second half of the year.

fulfillment providers, particularly food and grocery delivery, acquisitions highlighted the ongoing need to connect digital and physical retail. This includes omnichannel retail company Tulip Retail, which recently acquired Blueday, a store performance management system, and TimeKit, an advanced scheduling system. 3. Big tech firms’ retail advances have aimed to make shopping easier: Amazon, Facebook, and Google have all continued to invest in partnerships, platform expansions, and delivery and fulfillment capabilities that are making it possible for consumers to shop anywhere. 4. Europe and Africa have garnered more interest from retail tech investors: Year to date (YTD), both continents have seen their highest share of deals in the last 5 years: Europe has accounted for 22% of retail tech deals so far in 2020, while 3% of deals have been in Africa.

REPORT HIGHLIGHTS: 1. The shift to e-commerce has driven investment and valuations for 15 new retail tech unicorns: E-commerce enablement companies, as well as specialized selling platforms (such as online pharmacies and resale sites) have won investor interest as well as higher valuations. 2. M&A deals have focused on driving convenience and omnichannel connection: In addition to deals among online

5. In-store retail tech, e-commerce, and supply chain and logistics tech have all seen increased funding in H2’20: In the second half of the year to date, financing to in-store retail tech companies has jumped 152%; e-commerce funding has grown by 68%; and supply chain tech financing has increased 15%. While only in-store retail tech funding is likely to match 2019’s totals, investment continues to flow in all 3 areas as retailers and their partners rush to boost conversion and improve operations.

DIGITAL ISSUE NO.02 : MARCH 2021

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SPECIAL ARTICLE By Germany Trade & Invest

Scientists Without Borders

How Pfizer’s coronavirus vaccine breakthrough was achieved together with a previously obscure Mainz-based firm, BioNTech, which is now worth over a billion euros

Özlem Türeci is a Turkish-German physician and immunologist who teaches at the University of Mainz. Together with her husband Uğur Şahin, she founded two companies in the field of biotechnology, including BioNTech. In November 2020, in the midst of rising coronavirus cases across Europe and Germany’s second lockdown, there was a ray of light: the US pharmaceutical giant Pfizer, in collaboration with German biotech firm BioNTech, announced preliminary test results for a vaccine that was 95 percent effective. “Today is a great day for science and humanity,” Dr. Albert Bourla, Pfizer’s chairman and CEO, said in a statement at the time. He also paid tribute to his German partner.

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BioNTech is a billion-dollar husband-and-wife team consisting of CEO Uğur Şahin and his spouse and chief medical officer Özlem Türeci, both highly accomplished scientists and experts in immunology and immunotherapy. Şahin was born in Turkey and studied medicine at the University of Cologne before meeting Türeci at the Saarland University Medical Center. Their company usually specializes in cancer research, developing ways to harness the body’s natural ability to defend itself from bacteria and viruses.


Pfizer and BioNTech announced in March – when the pandemic was still in its infancy – that they were pooling their resources to accelerate their vaccine development program called Project Lightspeed. It was a logical step, since the two companies had already been working together on the research and development of mRNA flu vaccines since 2018. Lightspeed turned out to be an appropriate name. BioNTech was able to bring its first vaccine candidates to clinical development within less than three months. “Safety, speed and flexibility are of the utmost importance in reacting to the current pandemic,” the company said in a statement. The two companies began manufacturing tens of millions of doses at the end of 2020 and expect to produce more than 1.3 billion by the end of 2021. In part, this is thanks to the financial support of the German government, which in September invested EUR 375 million into BioNTech from its special coronavirus research fund.

the cooperation between the two companies has provided an ideal platform for the development of the vaccine. “We’re happy that the successful relationship between Pfizer and BioNTech made it possible for both companies to mobilize our resources in the face of this global challenge,” he said.

For Mikael Dolsten, Pfizer’s chief scientific officer and president of Worldwide Research, Development & Medical,

Source : https://www.marketsgermany.com/scientistswithout-borders/

DIGITAL ISSUE NO.02 : MARCH 2021

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SPECIAL ARTICLE By Germany Trade & Invest

The ABCs of CBD

One hot start-up sector in Germany at the moment is products made from the cannabis derivative cannabidiol or CBD. Evidence suggests that CBD can alleviate disorders ranging from anxiety and insomnia to epilepsy without creating dependence or having intoxicating effects. The World Health Organization has declared that there is no evidence of CBD causing any public health problems, which led the European Court of Justice to clear the way for its legal use with a ruling in November 2020. That’s served as a signal to start-ups. Forbes magazine has described the CBD market as “booming.” “This judgement was an important step toward getting rid of uncertainties about whether CDB products pose a health risk and are illegal,” Finn Hänsel, the head of

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Berlin start-up Sanity Group, told business newspaper Wirtschaftswoche. Sanity Group concluded EUR 20 million in series A financing last February, and its investors include 2014 Football World Cup winner Mario Götze. Its brand name Vaay is doing around a million a year in turnover, according to Hänsel. CBD products include bath salts, oils, sprays, lozenges and teas and are sold both online and in perfumery outlets. Source : https://www.marketsgermany.com/the-abcsofcbd-vaay/


Lots of New German

Medications

in 2020

Coronavirus may have dominated the headlines last year, but Germany’s pharmaceutical companies were busy fighting disease on a number of fronts. The German Association of Research-Based Pharmaceutical Companies (vfa) says that its members brought 32 medications with new active ingredients on the market in 2020. They include not only the Covid-19 vaccine developed by BioNTech and US partner Pfizer but also ten medications to combat cancer. “With the first Covid-19 vaccine, companies and regulatory authorities have started to the turn the tide of the pandemic,” said vfa President Han Steutel in a statement. “At the same time, companies continued to bring out new medications for patients with other diseases in 2020.” The vfa added that its members invest more than EUR 7 billion a year in medication research. Source : https://www.marketsgermany.com/lots-of-newgerman-medications-in-2020/

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Show preview by intercare asia 2021 The world is ageing rapidly. The number of people aged 65 and over will double as a proportion of the global population, from 7% in 2000 to 16% in 2050 or 1.44 Billion senior people. By then, there will be more the older people then children (aged 0-14 years) in the population for the first time in human history. In Asia, concerning of population become aging is growing a lot while there are many products and services penetrate to silver aging community Seniors nowadays are spending and planning their lives better than other. Supplemental nutrition and organic foods have been becoming very important to senior which they believe that healthy is the most important thing to make them living happily. They also tend to look out for more antiaging solutions to make them look younger, for example, beauty supplement and skin care products. Furthermore, they searching and applying the elderly supports from various aspects. Financial and funding are become more popular to the senior who would like to make sure that they can live with their live without financial struggle. Some of them also would like to plan their life to be living with nursing care center and life care taker too. Besides, seniors also want to spend their money for their hobby and lifestyle, like tourism, exercise, yoga course, spa and seniors’ products which these can related to their social community. In addition, they also would love to learn the updated technology throughout the world, like digital technology, smart phones, social media, home and living technology and other innovation that can advance their quality of lives.

Mr. Sakchai Pattarapreechakul, the Managing Director of N.C.C. Exhibition Organization Company Limited revealed that it could be considered that elderly market has high potential with demands covering several businesses based on Thailand’s situation which the number of elderly persons increases continuously. Entrepreneurs start to focus on elderly market increasingly in order to respond demands in long-term. Consequently, the value of elderly market reaches 107,000 million baht per year. Therefore, InterCare Asia is an event that answer the needs of lderly and health concerning people for retirement. Containing lifestyle, travel, Family’s Happiness, technology and innovation as well as innovative seminars that can be applied in daily life. This exhibition contains many categories providing to senior markets. Beauty equipment & goods, such as agingrelated products, beauty supplement & drink, diet foods, cosmetics, skin-care, body-care products. Elderly supports like, elderly centers, financial planning, life planning, nursing care services. Health food & supplement, for example food for patients, herb and organic food, nutritional supplement. Lifestyle & wellness, such as anti-aging product, fitness, recreational goods, senior tours, spa, yoga. Medical equipment & rehabilitation, digital technology, hearing & vision aids, household safety equipment, massage tools, medical care products, medical consultant, mobility equipment, oralcare, rehabilitation products, smart living technology, vehicles and designing for disability. In this event, there will be many interesting activities including conference on technology and innovation for elderly, Seminar in health care by specialist agencies, The Innovation for Aging Student Performance Contest (in Thailand), Activities to take care of both physical and mental health by MorChao Baan Foundation, Business Networking Zone, Interesting and fun activities from radio waves F.M. 96.5 MHz. and very interesting activity from Asia Pharmed magazines. The event is on 8-10 July, 2021 EH102 BITEC.

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DIGITAL ISSUE NO.02 : MARCH 2021

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Thailand news

By world health organization country office for thailand

SPOTLIGHT • On 22nd February, 89 new cases of laboratory-confirmed COVID-19 were announced by the Ministry of Public Health of Thailand bringing the total number of cases to date to 25,504. No new deaths were reported today. • Of the cases reported in Thailand to date, 95.5% (24,361) have recovered, 0.3% (83) have died, and 4.2% (1,060) are receiving treatment or are in isolation (736 are in conventional hospitals and 324 in field hospitals). • The 89 laboratory-confirmed cases reported today include • 16 individuals who arrived recently in Thailand and were diagnosed in quarantine facilities. • 59 cases detected through the routine surveillance system linked to occupational risk, visiting crowded places or contact with confirmed cases in Samut Sakhon (19 Thais, 12 Burmese), Tak (4 Thais, 7 Burmese), Pathum Thani (9 Thais), Nakhon Pathom (6 Thais), Ayutthaya (1 Thai), and Ang Thong (1 Thai). • 14 cases identified through active case finding in Samut Sakhon (2 Burmese), Pathum Thani (7 Thais, 2 Burmese), Nonthaburi (1 Cambodian), and Tak (2 Burmese). This brings the cumulative total in this group to 14,407 cases. • Of 73 cases acquired in Thailand, 42% were detected in Samut Sakhon, 0% in Bangkok and 58% in other provinces. • During the new wave (between 15 December 2020 and 22 February 2021), 21,267 confirmed cases have been reported, of which 5,922 were detected through the routine surveillance system, 14,407 through active case finding and 938 are in individuals who entered Thailand, detected through screening in quarantine. At present, 20,184 have recovered, 1,060 are receiving treatment, and 23 have died.

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• Confirmed cases in the new wave in Thailand have been reported in 63 provinces. The 12 provinces reporting more than 50 cumulative cases in the new wave are Samut Sakhon (15,953), Bangkok (950), Chonburi (653), Rayong (584), Pathum Thani (519), Samut Prakan (365), Chanthaburi (221), Nonthaburi (174),Tak (151), Ang Thong (121), Nakhon Pathom (109) and Samut Songkhram (70). UPDATE FROM THE CCSA • The situation in Pathum Thani Active case finding was carried out in 8 fresh markets and a public transport hub between 9-20 February. Of the 13,293 individuals tested, 422 (3.2%) tested positive for COVID-19. The majority of infections were reported from active case finding at Pornpat Market. • Vaccines The first batch of COVID-19 vaccines will arrive in Thailand on24 February. • Golf quarantine The first group of 41 golf tourists from the Republic of Korea arrived in Thailand on 18 February and are currently in quarantine at Artitaya Golf & Resort. They will be expected to strictly abide by the Department of Disease Control’s guidelines, e.g. take a swab test on day 0and a second one on days 5-7. Should results of the second test come out negative, individuals will be allowed to freely enjoy the resort’s facilities. • Infodemic As we are constantly exposed to a wealth of information each day, the World Health Organization recommends some ways in which you can navigate the infomedic (information+pandemic). Before believing or sharing any reading material, make sure to identify the source of information, read the entire story, verify the credibility of the author, and consult with trusted fact-checking organizations.


An excessive amount of information about a problem (infodemic) can have a negative effect on our lives. Here’s what you can do to mitigatethe infodemic.

EXPLAINER: SARS-CoV-2 coronavirus mutations and their implications for public health and vaccine effectiveness In this series, we have examined how the SARS-CoV-2 coronavirus often mutates when making copies of itself inside human cells, sometimes developing into new variants that cause the pandemic to accelerate and our immune systems - and vaccines - to respond differently. Understanding this threat is an essential first step; but what can we do about this problem? First, it is important to understand that each new infection gives the virus millions of additional opportunities to mutate. This is one reason why we must continue to make every effort to stop transmission by practicing public health and social measures such as distancing, masking, and hygiene. Second, we must urgently vaccinate all adults around the

world, beginning with healthcare workers and those most at risk of severe illness. As long as any group, country, or region remains unvaccinated, the virus remains a threat to everyone. Finally, we must carefully monitor the evolution of the virus through global epidemiological and laboratory surveillance. Together with national public health agencies and collaborating universities, the WHO coordinates virological surveillance to detect new variants, conducts risk assessments, communicates findings, and adjusts ourcontrol strategies as needed. One way the WHO accomplishes this is by supporting online databases that store and share genomic sequencing information (read more here) so that global experts can easily query and analyze the data. Closer to home, the Ministry of Public Health of Thailand also conducts genomic analysis on SARS-CoV-2 viruses, including infections identified in Alternative and State Quarantine facilities, and shares these data on public-access databases. It is likely we will continue to see new variants emerge until the majority of the world’s population has been vaccinated. The combination of public health and social distancing measures, global vaccination campaigns, and careful viral surveillance areour best options to bring this pandemic to a close. Source : https://cdn.who.int/media/docs/default-source/searo/ thailand/2021_2_22_eng_sitrep_155-covid19.pdf ?sfvrsn=c3ac34b6_5

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Event calendar ICPPS 20214 17-20 March 2021 Tokyo, Japan. www.icpps.org/index.html ICPPS 2021

CPhI Japan 2021 14 - 16 April 2021 Tokyo Big Sight https://www.cphi.com/ INFORMA MARKETS JAPAN

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Pharma Nect 7-9 April 2021 ICEC https://www.bioexpo.com.tr/ pharmanext Akdeniz Tanitim A.S.

Korea Pharm & Bio 2021 13-16 April 2021 Korea International Exhibition Center (KINTEX) www.koreapharm.org KYUNGYON EXHIBITION CORP.

INTERPHEX 20-22 April 2021 Jacob K. Javits Convention Center, New York, USA www.interphex.com Reed Exhibitions

Cosmofarma Exhibition 22-25 April 2021 BolognaFiere S.p.A., Bologna, Italy www.cosmofarma.com/en/ Bologna Fiere

Ausropharm 22-26 April 2021 Messe Wien http://www.austropharm.at REED EXHIBITIONS MESSE SALZBURG

HOSPEX Japan 24-26 April 2021 Tokyo Big Sight, Koto, Japan https://www.jma.or.jp/ hospex/en/index.html Japan Management Association

BIOMED Device 5-6 May 2021 Boston Convention & Exhibition Center www.biomedevice.mddionline. com INFORMA MARKETS

InterCare Asia 2021 8-10 July 2021 BITEC https://intercare-asia.com/ N.C.C. EXHIBITION ORGANIZER CO., LTD.

Thailand LAB INTERNATIONAL 2021 1-3 September 2021 BITEC www.thailandlab.com VNU Asia Pacific & STTA

Bio Asia Pacific 2021 1-3 September 2021 BITEC www.bioasiapacific.com VNU Asia Pacific & TCELS

ASIA PHARMED & HEALTHCARE THAILAND


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