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THE BENEFITS OF 3D PRINTING FOR DRUG DEVELOPMENT
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THE BENEFITS OF 3D PRINTING FOR DRUG DEVELOPMENT Keywords:Â Pharmaceutical technology, Impresion 3D, Drug development
Introduction 3D printing is a manufacturing process in which layer
materials to
form
advantages complex making
it
an
in
and
are
deposited
entity.
the
This
great
of
highly
production
economical
by
has
custom-designed
more
layer
products,
and
time-
saving. Presently, applied pharmaceutical 3D
printing
modeling
includes
(FDM),
appearance
(SLA),
fused
stereo and
deposition lithographic
binder
extrusion
Figure 1 . Based on the diagnosis, treatment, and
printing. 3D printing can be used to make
treatment plan, doctors print the drug where
molds
needed to suit the specific situation of each
to
directly
produce
using
materials.
pills
or
powdered
to
drugs
as
pills, raw
patient. Printed drugs have a precisely measured API (Active Pharmaceutical Ingredient).
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Custom 3D printed tablets
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3D printing improves drug delivery route
The
individual
their
characteristics
eating
habits,
of
people,
inheritances,
be
it
ethnicities,
3D
printing
technology
produce
to
reduce
quality of life and even the disease itself have
loose,
effects
swallowing difficulties, as in the case of
on
the
pharmacokinetics
pharmacodynamics
of
drugs,
and
however
3D
porous
can
making
fast
disintegrating
printing is a highly flexible process that allows
printing
designing
microneedles.
the
pill
size
or
fill
percentage
to
tablets
can
also
be
This
technique
tablets.
used
to
make
technology to
administer
3D
is a
a
precisely control the dose to meet the individual
painless
drug
needs of each patient.
through the skin, since the microneedles penetrate the skin and release the drug
Improvement in controlled drug
into
release 3D
pain
printing
structure
of
can
adjust
the
the
tablet
by
shape
and
selecting
internal
materials,
setting parameters, and designing models. You can control the release rate or time of the drug because the release curve of the printed tablets is linked to the shape of the drugs. The custom shape
created
by
3D
printing
changes
the
the
dermis
nerve,
so
without it
administration
is
of
stimulating
very
useful
drugs
the
in
the
such
as
transdermal insulin. In addition, new ways of using drugs have been achieved, such as
the
implantable
nanofluids
for
delivery
topical
device
with
immunotherapy
of
tumors.
Outlook into the future
surface area of the pill, which can control the strength and time of drug release. In addition, it is very useful for patients who require multiple medications suffering from several diseases. 3D printing
also
multiple
medications
polymers the
in
solves
a
single
different
independently
the
problem
compatible
in
with
formulation,
medications different
of
having multiple
ensuring
are places
that
released and
at
Although
3D
deficiencies
printing and
technology
high
cost,
as
has new
technologies develop, little by little it can be solved. In the future it is anticipated that
the
testing
effect of
improved,
of
medication
patients and
3D
will
and
be
printing
drug
greatly can
be
implemented in pharmacies and hospitals to improve people's quality of life.
different times.
3D bioprinting helps drug development 3D
bioprinting
drugs
are
could
help
approved
drug
by
trials
as
new
two-dimensional
cytology, animal testing, and clinical trials so it can
mimic
the
physiological
characteristics
of
living organs and perform drug testing on behalf of animals. In addition, it is very useful to find out the toxicity levels of new drugs. All credits of scientific information are for the authors of the scientific article creation! Scientific information reference: Xiao Zhu, H. L. (2020). 3D printing promotes the development of drugs. Biomedicine & Pharmacotherapy, 1-6. Link: https://www.sciencedirect.com/science/article/pii/S0753332220308374#tbl0005
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