NTP Radioisotopes SOC Ltd A subsidiary of Necsa Ltd Pelindaba, South Africa
NTP’S ROLE IN NUCLEAR MEDICINE GLOBALLY AND COOPERATION WITH BELGIUM
Mapula Letsoalo 2013 October 23
www.ntp.co.za
Depleted Uranium Fabrication Facility (Pelindaba) Contents
• Role in global Mo-99 supply • Role in SA nuclear medicine • Continued relations with IRE
Geographical GeographicalLocation LocationofofNTP NTPRadioisotopes Radioisotopes Pretoria
NTP located at the Necsa Pelindaba Site
OR Tambo Soweto
Johannesburg
The Real And Lasting Victories Are Those Of Peace In 1991, the South African government signed the
Non-Proliferation Treaty (NPT) and became the first and only nation to voluntarily declare and
dismantle its nuclear weapons
And they shall beat their swords into ploughshares ... – Isaiah 2:4
Mo-99 Production & Related Facilities
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Radiochemical Production Plant Commercial Office Radiopharmaceutical Production Plant Radioanalytical Labs SAFARI-1
SAFARI-1 Reactor Nuclear Reactor
Mo-99 Production at NTP Enriched Uranium Inventory
Fuel Production Plant
Nuclear Fuel Assemblies
SAFARI-1 Reactor Target Plate Irradiation
Target Plates
Irradiated plates
Depleted Uranium Inventory
Waste
Nuclear Waste Management
Radiochemical Production Plant Chemical Extraction and purification of Mo-99 Waste Disposal & Storage Facilities
Transport Container Design Manufacture, License NTP Generator Manufacture
International Market
Local & International Users
NTP -Product Portfolio IRE Cooperation •
Collaborative partnership since 1997
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Mo-99 Supply crisis
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Increased production output Mo-99 Supply - Crisis Conditions ARI 5%
NTP 40%
IRE 30%
Covidien 25%
Total: 8 000 Ci/week
RadioisotopeSource Source Containers Containers Radioisotope Depleted uranium fabrication facility
Radiochemical Transport Containers (1 500 Ci Mo-99, 125kg)
Subsidiary Subsidiary Companies Company
ďƒź NTP Logistics is a joint venture company between NTP Radioisotopes (51 %) and a BEE partner ďƒź Specialize in managing the logistics of dangerous goods including radioactive materials.
NTP ProductofPortfolio Conversion Mo-99 Production to LEU
2011 •Routine supply of LEU Mo-99 (June)
2010 2009 2008 •Cold and depleted uranium experiments
2007 •Theoretical feasibility studies
•NNR approval received for test stage •Hot runs commence
•Submission to Regulators (June) •Validation runs (July) •NNR approval routiine ops (Sept) •FDA approval for use in US (Nov)
Medicals Facilities Medical Facility 3
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Medicals & Industrials SAFARI-1 Cyclotron facility
Nuclear Medical Isotopes & Related Products Radiopharmaceuticals Radiopharmaceuticals NovaTec-P Tc-99m Generator, Cold kits F-18 FDG I-131 Capsules, Solution and MIBG
New Lu-177 dotatate
F-Choline
Subsidiary Companies Company
ďƒź NTP has a 100% shareholding in AEC-
Amersham SOC Ltd ďƒź Exclusive distributor in Africa of NTP's radiopharmaceutical products as well as
a range of life science research and other products.
Corporate Social Investment PET/CT Scanner donated to people of Western Cape Located at Tygerberg PET/CT Centre Official opening - April 2012
Subsidiary SubsidiaryCompanies Company
Fully-owned subsidiary company NTP Radioisotopes (Europe) S.A.
Established on 1 February 2013 Located in Belgium – IRE site Manufacturer and distributor of gamma-radiography equipment used in the non-
destructive testing (NDT) industry, including sealed radioactive sources containing Ir192, Se-75 and Co-60, as well as the GammaMat range of NDT projectors and accessories
Also manufactures a range of Ir-192 brachytherapy products
Subsidiary ConclusionCompanies Necsa/ NTP’s nuclear technology is making a major contribution to the economy
and to our country’s global standing.
Subsidiary Companies Thank you very much!