PROBIOTICS JUST GOT SMART

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PROBIOTICS JUST GOT SMART


Content: 1. Background

3.3.2 Boosted immune system

1.1 What is the human microbiota?

3.3.3 Enhanced cancer defenses

1.2 How do microorganisms affect the body?

3.3.4 Allergy prevention

1.3 What are the main types of bacteria which affect the body? 2. Dysbacteriosis: microbial imbalance 2.1 What is dysbacteriosis? 2.2 How does dysbacteriosis affect the body?

3.4 Other benefits of probiotics 4. Bio-In 4.1 Standard probiotics: some problems 4.2 Bio-In’s distinguishing features 4.2.1 The Synbiotic system 4.2.2 Individually personalized

3. Probiotics 3.1 How is microbial balance restored? 3.2 What are probiotics and how do they work? 3.3 What are the key benefits of probiotics 3.3.1 Anti-aging

4.2.3 Carefully balanced 4.2.4 Guaranteed effectiveness 5. User testimonials


1.1 What is the human microbiota? The term microbiota refers to all the microorganisms living in the human body. Elementary microorganisms outnumber our own body cells by at least 10 to 1, while the total number of microbial genes outnumber the total number of human genes by 100 to 1.

1

99

This means that 99% of the genetic code in your body is not yours. It actually belongs to microorganisms.


1.2 How do microorganisms affect the body? Microorganisms significantly impact a range of health and wellbeing factors. These include: 1 Early aging

5 Digestion

2 Appearance

6 Allergies

3 Immunity

7 Emotional well-being

4

Carcinogens


1.2 How do microorganisms affect the body? Bacteria are both the most numerous and the most impacting microorganisms living in the human body.

The highest concentrations of bacteria are found in the stomach, the intestines and the vagina, on the skin, and around the rectum. Bacteria also thrive in the mouth, within the oral cavity (the airways), in the joints, inside the urinary tract and in many other locations.


1.3 What are the main types of bacteria which affect the body?

1. Good bacteria (probiotics). Probiotic strains affect our body in many positive ways. They can be found in the digestive tract, on the skin, and in our airways.

2. Pathogenic bacteria. These are disease-producing microorganisms. They are the cause of a number of complaints which include early aging, dermatitis, digestive problems, allergies and carcinogens.

3. Opportunistic pathogenic bacteria. These are the natural occupants of various parts of the body. They cause diseases when host defenses suddenly drop.


2.1 What is dysbacteriosis? An imbalance in intestinal microorganisms (microflora) is called dysbacteriosis. Dysbacteriosis is when the number of good bacteria decreases while the number of pathogenic ones increases. It can be caused by: stress an unhealthy diet diarrhea or chronic constipation antibiotics and other pharmaceutical products -

low levels of physical activity


2.1 What is dysbacteriosis? 1

Common symptoms of dysbacteriosis: 1

Fatigue, depression

2

Halitosis

3

Abdominal swelling

4

Nausea and occasional vomiting

5

Stomach discomfort or pain

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Excess of intestinal gas

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Constipation or diarrhea

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4

3

5

6 7


2.2 How does dysbacteriosis affect my body? 1. Poorer digestion and metabolism:  Poor absorption of nutrients  Development of obesity  Leaky gut syndrome, resulting in food intolerances and pain  Increased level of free radicals and toxins  Lack of vitality in skin and hair

2. Weakened immune system:

3. Associated Conditions:

 Allergic reactions

 Early aging

 Increased carcinogenic damage to cells

 Chronic fatigue syndrome

 Chronic inflammation of both organs and tissue  Weakening of other protective systems (endocrine, nervous)

 Psychological conditions including depression  Type 2 Diabetes  Increased risk of cardiovascular diseases (i.e. atherosclerosis)


3.1 How is microbial balance restored?

Microbial balance is achieved by restoring the perfect good bacteria to bad bacteria ratio. 20% Bad bacteria

80% Good bacteria


3.2 What are probiotics and how do they work? Probiotics are the living microorganisms that have a healthy effect on the human body when taken in the right doses.* When probiotics are introduced into the digestive system, they compete with pathogenic bacteria, and by doing this, restore the balance of good to bad bacteria. Probiotics 80% Bad bacteria *official definition of probiotics by World Health Organization and Food and Agriculture Organization

80% Good bacteria


3.3 What are the key benefits of probiotics?

Probiotics restore the balance of microorganisms in the body. This helps to:

- prevent early aging - boost the immune system - enhance cancer defenses - reduce allergic reactions


3.3.1 Anti-aging Early aging is caused by toxins and free radicals in the body. It also occurs when the body does not receive enough vitamins, minerals and antioxidants. According to scientific research, good bacteria in the gut destroy the toxins and free radicals that cause early aging. Probiotics also help the body to digest and absorb nutrients from food. As a result, the body receives more of the antioxidants, vitamins and minerals it requires to maintain optimum health.


3.3.1 Anti-aging

Probiotics enable organic chemicals called polyphenols to be absorbed by cells in the digestive system. Polyphenols activate telomerase, enzymes that are able to restore the cells’ telomeres, thus protecting genetic material from destruction and early aging.*

*Wang XB, Zhu L, Huang J, Yin YG, Kong XQ, Rong QF, Shi AW, Cao KJ.Resveratrol-induced augmentation of telomerase activity delays senescence of endothelial progenitor cells. Chin Med J (Engl). 2011 Dec;124(24):4310-5.


3.3.1 Anti-aging Telomere damage is also caused by psychological stress. Probiotics produce various anti-stress compounds such as dopamine and serotonin which: - reduce levels of stress hormones like cortisol, preventing damage to cells and reducing aging; - enhance emotional well being; - alleviate depression and anxiety; - increase brain performance, cognitive functions, and memory*

*Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5.


3.3.1 Anti-aging The damage to DNA that leads to premature aging is also caused by free radicals. Probiotics strengthen the natural antioxidants in the body which capture and neutralize free radicals.* This prevents DNA damage and slows down the aging processes.

*Lutgendorff F, Trulsson LM, van Minnen LP, Rijkers GT, Timmerman HM, Franzén LE, Gooszen HG, Akkermans LM, Söderholm JD, Sandström PA. Probiotics enhance pancreatic glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2008 Nov;295(5):G1111-21.


3.3.2 Boosted immune system Probiotics benefit the immune system in a number of ways: 1) They create a barrier in the gut that prevents malicious bacteria from penetrating into the blood stream. 2) They stimulate the production of protective mucous in the gut. 3) They train the bodies immune cells. 4) They suppress inflammatory reactions.


3.3.2 Boosted immune system Training the immune cells The contact of the gut’s epithelium with bacteria stimulates the production of immune cells, which then spread through the entire body. The good bacteria cells train and activate immune cells to recognize and destroy pathogens. The immune system is tightly connected with other important bodily systems like the endocrine system. So, strengthening the immune system affects other physiological processes and improves general health.


3.3.3 Enhanced cancer defenses Cancer is the rapid and uncontrollable emergence and reproduction of mutated cells. Cancer has a number of causes:

Mutation of human cells when transmission of genetic information fails. Impact of free radicals on cell metabolism.

Impact of external factors like tobacco smoke, pesticides, bacterial toxins, alcohol and UV radiation.


3.3.3 Enhanced cancer defenses Good bacteria help protect the body against cancer

1) They destroy carcinogens (cancer causing agents) before they can cause harm, and reduce their activity in the digestive tract.

2) They protect the DNA from free radicals that cause cell mutations.

3) They produce fatty acids and vitamins B7, B9, B12, and K, all of which protect genetic material and reduce the risk of mutations that cause cancer.

4) They help to regulate the growth of proliferating cells to prevent cancerous tissue development.


3.3.4 Allergy prevention Allergies are improper reaction to certain compounds that are actually safe, and are caused by failures in the immune system.

The World Health Organization has identified allergies as the largest epidemic disease in children.

25% of people are susceptible to allergies.

In the last 20 years, the number of asthmatics in the world has increased by 160%.


3.3.4 Allergy prevention Allergies and probiotics Scientists have proved that there is a direct link between allergies and the balance of bacteria in the intestines. People with low levels of good bacteria - like Bifidobacterium and Lactabacillus - and high levels of pathogenic bacteria are more likely to suffer from allergic reactions. By improving the ratio of good bacteria to pathogenic bacteria, probiotics reduce the likelihood of allergic reactions.


3.4 Other benefits of probiotics

1. Normalized digestion

2. Improved metabolism

Probiotics:

Probiotics:

 release agents that fight pathogenic bacteria;

 produce vitamins (В7, В9, В12, К);

 normalize intestinal gas production;

 protect from free radicals;

 prevent obesity.

 prevent cardiovascular diseases.


4.1 Standard probiotics: some problems

Many standard probiotic products suffer from three main defects:

Up to 75% of probiotic cultures die before the packet is opened.

Many probiotics are susceptible to attack by saliva and stomach acid, rendering them ineffective.

Up to 60% of probiotics fail to establish themselves inside the digestive system and are flushed out.


4.2 Bio-In’s distinguishing features

The key strengths of Bio-In are that;

It is a Synbiotic system

Each program is individually personalized

We guarantee the effectiveness our probiotics


4.2.1 The Synbiotic system

A Synbiotic system is one which contains a fusion of three essential elements. These are: PROBIOTICS living friendly bacteria

COBIOTICS special nutrients that provide nutrition both to the human cells and the resident probiotics

PREBIOTICS non-digestible sugars* that feed the probiotics

* non-digestible sugars – they cannot be digested by human enzymes and absorbed in the small intestine. Therefore they are able to reach the colon and nourish probiotics, strengthening their reproduction.


4.2.1 The Synbiotic system

Bio-In contains 14 patented probiotic strains, along with prebiotics, antioxidants, herbal extracts, vitamins, minerals and cobiotics. There are 1.5 trillion living cultures of the following probiotic stains in every program:

Lactobacillus

Lactococcus

Bifidobacterium

Streptococcus


4.2.1 The Synbiotic system

The Bio-In systems works just like planting a seed:

The first Digestico stage prepares the ground, removing weeds and loosening the soil.

Probiotics are the seeds themselves.

Prebiotics and cobiotics act like water and sunlight, nourishing and hydrating the seeds, guaranteeing their healthy growth and continued harvest.


4.2.2 Individually personalized

Every 120 day Bio-In program is individually tailored to meet the needs of each user.


4.2.2 Individually personalized

Bio-In users receive:

An individually tailored program.

A personal detoxification plan and nutritional recommendations.

A Quality of Life Coach that provides assistance and guidance during and after the Bio-In program.


4.2.3 Carefully balanced

The 120 day program consists of 8 stages. The first stage cleanses and prepares the intestinal system, while the next six stages are designed to guarantee that our probiotics are able to establish themselves and thrive. The final stage is specifically engineered to maximize Bio-In’s effectiveness.

Day 1

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Day 120


4.2.4 Guaranteed effectiveness

Bio-In is currently the only company to guarantee that all the living probiotics in each sachet remain alive until the product expiration date

Bio-In utilises state-of-the-art packaging which guarantees that the probiotics retain their vital capacity at room temperature


5. User testimonials

Svetlana Efimova

Solvita Gutmane

Isak Levi

The Bio-In program helped me increase my self-discipline and helped me lose weight. I also really liked that it was divided into stages as this helped me to keep track of my progress, and see how the program was improving my body.

The program inspired me to stay healthy and exercise regularly; it also helped me to transform my diet for the better. I now feel that my quality of life has really been improved, and look forward to following the program again with my daughter!

My body now functions much better. They say perfection knows no limits, but I still think that with Bio-In you can reach them!


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