Winter 2013 1

500 Helendale Rd Suite L20 Rochester, NY 14609 585.288.0890

Volume 6, Number 1 Winter 2013

Advancing Medicine. Changing Lives.

Advancing Medicine. Changing Lives.

What’s InsideNew Website

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Compensation Chart

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“Ask what you can do for your country”

2

Forgot your flu shot?

2

Got High Cholesterol?

2

New Drug for Diabetes

3

Rheumatoid Arthritis Sufferers

3

Have you had a heart attack?

4

Rochester Ranks Second

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Increased Protection for your Children?

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Referral Program

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New Technologies

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Giving Back

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500 Helendale Rd Suite L20 Rochester, NY 14609 585.288.0890

Same Address New Website! www.rcrclinical.com

Giving Back

RCR partners with Tyler Putnam Foundation Tyler Putnam, an athletic and vibrant 16 year old at Irondequoit High School, died tragically of Meningitis on July 7th, 2011. To honor Tyler’s memory, and to continue his legacy of giving back to others, Tyler’s dad Lindsay and sister Shannon, established a charitable foundation in Tyler’s name.

As Tyler was a highly-skilled hockey player who loved the game, the foundation that bears his name provides assistance to Rochester youth who also love the sport, but cannot afford it. The Foundation website is: tylerputnamfoundation.org

Compensation Chart Low Testosterone up to $1500 Adult Cold Sores up to $650 Irritable Bowel Syndrome up to $430 High Cholesterol up to $385 Gout with Cardio Issues up to $500 R E S E A R C H

Healthy Volunteer HPV Vaccine Meningitis Vaccine Rheumatoid Arthritis Osteoarthritis of the Hip

up to $600 Available Available up to $504 up to $810

S T U D I E S

Adult Cold Sore High Cholesterol Rheumatoid Arthritis

Irritable Bowel Syndrome HPV Vaccine (16-26 yrs) Osteoarthritis of the Hip Healthy Volunteer

Low Testosterone Type 2 Diabetes Gout with Cardio Issues

CONTACT US NOW to participate at 585.288.0890 volunteer@rcrclinical.com

Tyler died of Meningitis B. Here at RCR, we are conducting a research study of an investigational vaccine to see if it will protect against Meningitis B, a form of Meningitis also not covered by Menactra®.

For every subject enrolled in the study, RCR will be making a donation to the Tyler Putnam Foundation. We welcome this opportunity to honor Tyler, and to carry-forward his legacy of selfless service to others.

COME BE PART OF THE SOLUTION

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Bin Laden is Dead.

Is Terrorism?

585.288.0890

585.288.0890

New Technologies:

Life after Lipitor

Making weight loss easier

The next best cholesterol drug?

Probably not.

Their heyday may be ending.

We’ll need healthy 18-40 year olds who have never had a Smallpox Vaccine.

The good news is that the risk of getting smallpox is zero, and there is a monetary stipend availalbe.

Becoming aware of your eating and exercise habits is the first step towards making positive changes. The easier it is to record both, the more likely you will stay on track.

An entirely new class of cholesterol-lowering medications are being developed. They have the potential to be the next “blockbuster” drugs on the market.

We have worked on vaccines against Anthrax & Plague.

What’s next? An investigational Smallpox Vaccine research study.

Want to lose those pounds gained over the holidays? Sorry to say, but there is no magic. Weight loss is still achieved by eating fewer calories than you burn. But why not use the newest technology to help you eat less and exercise more?

Lipitor and fellow statin drugs have been the mainstay of treatment for high cholesterol levels.

Which is why RCR has been working on Department of Defense funded contracts to develop vaccines against agents of bioterrorism.

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Able to drop LDL (‘bad cholesterol’) levels by as much as 70%, with minimal risk of side-effects, these new investigational drugs look very promising.

There are many free or low cost programs or apps which can be downloaded for use on computers, smart phones and tablets. Some programs will allow you to take a picture of a food label’s bar code instead of looking at food lists.

Known as “PCSK9 Inhibitors”, they work by helping your body ‘clean’ the blood of excess LDL cholesterol, which is then simply excreted.

Most programs keep lists of your “frequently eaten or favorite foods”, which makes it even easier to add up your daily food intake. Others track your daily nutrient intake as well as your weight, adjusting the calorie level as you shed pounds.

These new medications will benefit those who cannot take statins because of side-effects, or those whose cholesterol remains high despite taking a statin.

Concerned about a specific nutrient? Watching your calcium intake? Electronically track your intake over time, and adjust your intake accordingly.

We are enrolling volunteers for several of these studies.

Need to get moving? The best way to do that is to put you in competition with yourself by tracking your daily steps. Some step counters also track your sleeping habits and can be synced with dietary analysis software.

Call to see if you qualify. 585-288-0890.

Want some new recipe ideas? Many excellent low-calorie recipe websites keep you motivated with weekly emails of healthy recipes, complete with other’s comments.

Fear Not!

Here’s a list of products and websites to get you started. This is by no means a complete list, nor do we have stock in any of these companies!

We have a flu shot study for you, which utilizes the flu strains from the approved 2012/2013 flu shot.

Dietary Analysis software/apps www.fitday.com www.myfitnesspal.com

The study is evaluating new investigational technologies in how flu vaccines are formulated and manufactured.

Step/Sleep counters: Fitbit website: www.fitbit.com

There is no placebo in this study. Everyone will get a vaccine.

Websites for Healthy recipes: www.myrecipes.com/healthy-diet www.livebetteraamerica.com www.eatingwell.com

Forgot your flu shot?

Call today! If you are age 18 - 65. See if you qualify.

585-288-0890 or www.rcrclinical.com

© 2008 Rochester Clinical Research

Publishers and Editors:

Why volunteer for a clinical research study?

Adam Larrabee & Bev Shaff

The reasons might include a sense of personal

editor@rcrclinical.com

satisfaction, the opportunity to improve your

Contributing Writers:

health, and the chance to make a difference for

Michael Brennan, Vicky Fink

others as well. Come, be part of the solution.

F i n d

“Like” RCR on Facebook for access to latest study opportunities and information on our Free Health screening events.

u s

o n l i n e

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585.288.0890

Increased Protection for your Children?

Meningitis B Vaccine For 10-25 year olds “When my teenagers got their meningitis vaccines, I thought they were protected against all causes of the dread disease.” said Michael Brennan, FNP “I was wrong.”

The currently licensed meningitis vaccines, such as Menactra®, do not provide immunity against the Meningitis B strains, which cause one-third of the cases of bacterial meningitis in the U.S. So researchers are evaluating this new investigational Meningitis B vaccine.

Participants in this study will receive 3 shots over 6 months, and there is no blood work involved.

Call today to see if you or your child qualifies. 585-288-0890

585.288.0890

W W W. R C R C L I N I C A L . C O M / S T U D I E S

Rheumatoid Arthritis Sufferers You are not forgotten!

Such a devastatingly disabling disease, for which new and effective therapies are sorely needed.

Keith Pryhuber. If you have RA, then RCR is the place to be!

Call now! 585-288-0890

If you have rheumatoid arthritis, we are currently enrolling for 3 different studies.

In our experience, participants in our RA studies derive a lot of satisfaction in knowing that they are helping to develop new therapies for others with their disease.

There is altruism at the heart of the motivation to participate in such research. Our RA study volunteers are everyday heroes – improving the lives of others.

We are fortunate to have 2 board certified Rheumatologists on staff; Dr. Tammi Schlotzhauer and Dr.

Dr. Tammi Schlotzhauer Rheumatology & Internal Medicine, Assistant Medical Director Dr. Shlotzhauer, a practicing rheumatologist, is boardcertified in both internal medicine and rheumatology. She has participated in over 185 clinical trials.

New Drugs for Diabetes Oral Insulin!

For diabetics taking metformin, we have two studies of new investigational oral therapies.

Gardasil® The next generation Researchers are trying to make a good vaccine even better.

Currently, Gardasil® helps protect against 4 strains of HPV (Human Papilloma Virus) that cause genital warts and can lead to cervical or penile cancers.

Our study is of an investigational HPV vaccine to cover 9 strains of HPV. This study is enrolling gay or bisexual men, ages 16-26.

Call for more information or to volunteer! 585-288-0890 or www.rcrclinical.com

Volunteer Referral Rewards Program If you have participated in a study with us and enjoyed it, please tell your friends, family members and coworkers!

Until now, insulin has always had to be given by injection. This exciting new medical breakthrough is evaluating an insulin that can be taken in pill form.

Two pills at bedtime is the simple regimen. If it works, and gets FDA approved, diabetics around the world will be celebrating!

We have another study of a GLP-1 medication, similar to Byetta® or Victoza®, which is taken orally. Again, this potentially marks a huge step forward for diabetes therapy.

If you have diabetes, we invite you to come be part of the solution!

Call to see if you qualify. 585-288-0890, www.rcrclinical.com or volunteer@rcrclinical.com

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585.288.0890

What’s Inflammation got to do with Heart Disease?

585.288.0890

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Rochester Ranks Second in Nation for Volunteering

Heart Attack?

Taking aim at prevention.

If you have had a heart attack, you may qualify for our long-term research study of an anti-inflammatory. The investigational drug is being evaluated to see if it can help prevent heart attacks and strokes.

This is a huge study, involving more than 17,000 people around the country.

The theory that inflammation may be as important as cholesterol in causing cardiovascular disease is getting a lot of attention.

It is believed that it is the underlying inflammation that enables plaque build-up inside the arteries.

If you or someone you love has had a heart attack, please call 585-2880890 to learn more about this pivotal research study.

And why you may need your CRP level checked…

Your risk of a heart attack in- mg/L) of CRP appear to be associcreases with age, with high choles- ated with an increased risk for heart terol, high blood pressure, and smok- disease, and are measured using a ing. While there has been a direct high sensitivity CRP test (hs-CRP). relationship between high LDL levels (the ‘bad’ cholesterol) and heart at- Who should have their hstacks, a full 50% of first heart attacks CRP checked? The American occur in people who have LDL levels Heart Association (AHA) states that high sensitivity CRP (hs-CRP) considered to be ‘normal’. may be useful in evaluating those Is there another risk factor at moderate risk for heart disease we’ve been missing? Re(based on their number of risk searchers have found compelling factors) – to see if more intensive evidence that inflammation plays treatment is warranted. Those at a role in the formation and rupture high risk should be treated aggresof artery-clogging plaque deposits. sively regardless of their hs-CRP Some individuals appear to be at level, and those at low risk need not higher risk of heart attacks simply be tested. because they have higher levels of Should my elevated hs-CRP inflammation in their blood vessels. be treated? If your hs-CRP level So what’s C-reactive protein? is elevated, it should not be ignored.

Produced by the liver, C-reactive Our research study of an invesprotein (CRP) levels rise when there tigational drug for people who is inflammation in the body, and have had a heart attack closely these levels can be checked by a monitors the study participant’s blood test. Small elevations (1-5 hsCRP levels.

Call 585-288-0890 www.rcrclinical.com volunteer@rcrclinical.com

Rochester, NY ranks second in the nation for volunteering in a new report from the Corporation for National and Community Service and the National Conference on Citizenship.

The top 5: Minneapolis-St Paul-Bloomington, MN-WI (37%) Rochester, NY (34.8%) Seattle-Tacoma-Bellevue, WA (33.4%) Salt Lake City, UT (33.2%) Jacksonville, FL (32.2%)

Special Thanks!

To our volunteers.

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