ABSTRACT The journey of anything tangible depends on its ability to evolve in response to its environmental context. Evolution is a never-ending process. Matter continually adapts to survive the ever-changing environment. Be it the evolution of man, that depends on the climate he lives in, the availability of resources he uses for survival, the culture he adopts, and the mutation of his genes; or the evolution of styles of design, art, buildings, etc. which change from time to time to create new trends and endure in the market. The evolution of tangible and intangible matter is in constant response to the other. It is an endless cycle. A classic example of which is climate. Man adapts to the climate he lives in, though it is none other than him who is responsible for the changes in the climate due to the resources he utilizes. The best reference for this is global warming. The immediate environment in which man lives, works, recreates, and rejuvenates influences his activities and capabilities. The design of a workplace can influence one’s intellectual or productive behavior. Design here consists of not just the aesthetic features but also the environment comprising of climate, nature, sound, light, etc. The thesis aims at studying this correlation between the environment and man and addressing its impact on the physique and psyche of man. It also intends to investigate the effect of psychology on physical well-being through control of the immediate built and unbuilt environment. The target study is focused on cancer patients and their needs and requirements during and after treatment.