June 7 19

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MEDICALEXAMINER

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CBD

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JUNE 7, 2019

AIKEN-AUGUSTA’S MOST SALUBRIOUS NEWSPAPER • FOUNDED IN 2006

The ABCs of

CBD: WHAT YOU NEED TO KNOW – PART 1: THE BASICS Written by Augusta pharmacists Chris and Lee Davidson

There is a new set of prodbut it is quickly going mainCB-2. ucts gaining huge popularity stream. Unfortunately, there   CB-1 receptors are found in the nation that are being are not enough mainstream primarily in the central nertouted as being good for medical studies to back up vous system (CNS), which is almost everything that ails these fantastic claims, at least the brain, nerves, and spinal you. These products, based not yet. Research is having to cord. CB-2 receptors primarion different formulations of play catch up to this rapidly ly handle the peripheral nercannabidiol (CBD) oil (proevolving chapter in medicine. vous system (PNS) - essennounced can-uh-b -DIE-all),   The purpose of the Entially everywhere else. There work by regulating the body’s docannabinoid System is to are more potential receptors endocannabinoid system. maintain homeostasis, or being studied, but they have The endocannabinoid system balance, within the body. The not been definitively identi(ECS) helps to regulate a receptors themselves are the- fied yet. Between these two broad range of physiological orized to be “smart” in that primary receptor types, virtuprocesses throughout our they are only able to act on ally all the body’s functionbodies. The latest research the bodily functions that are ing and responses, including shows that when the ECS is currently out of balance in motor functions, how pain is disrupted it can be associated order to maintain a precision felt, keeping digestive syswith a long list of common level of homeostasis. In other tems functioning, controlling illnesses and medical conwords, they work only when immune responses, moderditions. This is why there and where they are needed ating moods, enabling (or are claims made about CBD without going overboard. disabling) the ability to sleep, being a treatment for almost There are multiple types of helping to remember inforeverything. This type of treat- receptors in the ECS, but mation, etc., are managed. SCRB19012CR-Medical Ad-outlines-PRINT-2.pdf 1 the 5/29/19  There 9:14 AM is at least one group ment used to be reservedExaminer-June for there are two that handle the alternative medicine set, bulk of the work: CB-1 and of researchers who believe e

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that when the body cannot maintain its perfect balance, it may indicate that the person has clinical endocannabinoid deficiency – that they are either lacking enough of one or the other types of receptors or that they have too much of a specific enzyme that blocks the receptors. The theory is that with such a deficiency, a person may be more prone to certain conditions such as fibromyalgia, certain GI disorders (including IBS), chronic pain, migraines, depression, anxiety, and more. There also seems to be a strong connection between the ECS and the immune system, suggesting that the ECS may actually play a role in autoimmune diseases.   CBD can be useful in the management of many conditions and is being investigated for potential benefit in many more. Again, there is a lot of anecdotal information available, but for the most part the scientific studies are ongoing.   CBD products are marketed as supplements, not as over-the-counter drugs, so just like other vitamin and supplement products they cannot make any actual claims about curing or treating any

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disease. This also relieves the manufacturers of the obligation to publish dosing guidelines, so the best bet is to talk to your pharmacist and remember that each person is different. You may have to adjust the dose to find what works for you and your condition because there is no one right answer. Make sure to tell your pharmacist about your current medical history and other medicines you take since CBD can potentially interact with other medicines. Be particularly careful to mention seizure medications and blood thinners since these are two big areas of Please see CBD page 6


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