Pharmaceutical & Cosmetic Review Africa Q1 2021

Page 22

PHARMA FOCUS: TABLETTING & ENCAPSULATION

Fette Compacting supports By-Health to achieve

efficient production By-Health, a manufacturer of dietary supplements based in China, has completely revolutionised the way it produces Keylid glucosamine tablets with the installation of several tablet compacting machines from Fette Compacting. The technology fully supports By-Health’s initial move to transparent manufacturing and its subsequent transformation to intelligent production.

F

OUNDED IN OCTOBER 1995, By-Health is a publicly listed company in China that specialises in the research and production

of health supplements. After 20 years of development, it has become one of the most benchmarked enterprises in the Chinese dietary supplement industry. In 2012, By-Health commissioned the third phase of its factory, which boasts a total annual production capacity of up to 5bn tablets, 3mn soft capsules, 500mn hard capsules, 250mn bags and 15mn cans of powder vitamin and dietary supplements respectively. The factory is certainly one of Asia’s leading dietary supplement manufacturing bases in terms of hardware. By-Health also developed the site as the first intelligent ‘transparent factory’ within China’s dietary supplement industry. A transparent factory is one where production is open or visible to the public through the use of transparent

In the past, By-Health operated different

Fette Compacting’s P3030 Facelift tablet press in operation at By-Health’s compacting department

workshop walls, which means people can see

tablet presses from domestic Chinese and foreign

By-Health’s production process and advanced

brands, yet with its production expansion, many

production equipment. This concept officially

problems occurred. These included:

compression room, affecting the placement

became an AAAA-grade industries tourist

• Reduced efficiency affected by machine quality

of other process equipment. In addition,

attraction in China in 2018. Additionally, an online

– The failure rate of the original imported tablet

the aesthetics of the machine, particularly

and real time site visit is possible via the internet

press was high. An engineer from the supplier

the outer surface, was very rough and not

and enabled by webcams.

was frequently required to conduct on-site

suitable for public display, according to the

maintenance, and eventually the machine was

manufacturer’s perspective. • High powder leakage and very low yield – The

DEMANDING PRODUCTION REQUIRES A ROBUST SOLUTION

sent back to the supplier’s factory for repairs. By-Health criticised the slow response of

raw material powder of Keylid is yellow in

In 2012, the Keylid glucosamine chondroitin

the foreign machine supplier and its lack of

colour. When operating with the domestic

sulphate calcium supplement was introduced

sufficient stock of spare parts, which caused

tablet press, the filling parts, turret surface

to market. This dietary supplement is intended

a delay in its planned manufacturing schedule.

and discharge chute all became covered with

to support the bone joint health of middle-aged

It took several months for the supplier to send

a large amount of the yellow powder. The

people and geriatrics. At present, the annual

the tablet press back to the producer’s factory

sales of Keylid are more than 1bn Chinese Yuan

for repairing. By-Health, which has a great

Renminbi ($15bn). Its year-on-year growth was

demand for higher output, simply

to produce bad tablets became high on the

nearly 200% in 2018.

couldn’t accept this.

domestic press. This equipment had problems

Keylid contains calcium carbonate, which

• Domestic tablet press becomes rudimentary

product yield was also very low. • Unstable tablet quality – The probability

with the spindle eccentricity tolerances and

requires high compression forces during the

– The output of the press from the Chinese

great pressure measurement deviation.

tablet compression process. Consequently, high

supplier was 200 000 to 300 000 tablets per

Ultimately, the rate of bad tablets became

performing tablet compacting machines are the

hour. Its footprint was 1 700mm × 2 000mm

most important production equipment in the

× 2 100mm with a weight of 8 000kg, which

These problems forced By-Health to look for a

manufacturing process chain of this product.

occupied too much space in By-Health’s

suitable alternative tablet press that could fulfil

22

QUARTER 1 2021 // P&C AFRICA

unacceptably high.


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