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Filler-binder optimises production of fizzy tablets and powders
Beneo’s galenIQ 721 filler-binder overcomes challenges in effervescent dosage manufacturing. The excipient is easy to use and it has improved technical properties.
To improve the taste and stability of effervescent tablets and powders, Beneo presents galenIQ 721. This filler-binder enables pharmaceutical and nutraceutical manufacturers to target consumers who have difficulty swallowing standard tablets.
As a non-hygroscopic, water-soluble and directly compressible excipient, galenIQ 721 also provides high content uniformity and production efficiency for effervescent applications.
A convenient and appealing dosage form
Effervescent dosage forms offer distinct advantages compared to traditional tablets. For instance, many patients have problems swallowing tablets. Effervescent powders and tablets offer a more convenient way to deliver medicines or dietary supplements. They dissolve upon contact with water to release carbon dioxide and create a drink. In addition, they can be used to formulate pharmaceuticals that are difficult to digest, cause stomach or oesophageal irritation or which rely on a rapid onset of action, such as analgesics.
While the dosage form is highly convenient, manufacturing effervescents can be challenging. A non-hygroscopic, direct compression filler-binder such as galenIQ 721 is needed to produce highly stable tablets. This excipient ensures high content uniformity and facilitates production. It also has a sugar-like taste profile, a pleasant mouthfeel and can enhance the palatability of effervescent formulations. Available locally from Savannah Fine Chemicals, galenIQ 721 is non-cariogenic, sweet and tooth friendly.
Enhanced product development
Dr Maj-Britt Cepok, head of business development, pharma, Beneo, comments: “Fizzy tablets are ideally suited to administer a wide range of light- and oxygen-sensitive active ingredients and those which require a large dose. In addition, effervescent preparations are more appealing to consumers than traditional dosage forms. galenIQ 721 helps manufacturers to tap into this market and enhance their development programmes.” •
Beneo – www.beneo.com
Savannah Fine Chemicals – www.savannah.co.za
