INGREDIENT & FORMULATION INNOVATION
Filler-binder optimises production of fizzy tablets and powders Beneo’s galenIQ 721 filler-binder overcomes challenges in effervescent dosage manufacturing. The excipient is easy to use and it has improved technical properties.
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o improve the taste and stability of effervescent tablets and powders, Beneo presents galenIQ 721. This filler-binder enables pharmaceutical and nutraceutical manufacturers to target consumers who have difficulty swallowing standard tablets. As a non-hygroscopic, water-soluble and directly compressible excipient, galenIQ 721 also provides high content uniformity and production efficiency for effervescent applications.
dissolve upon contact with water to release carbon dioxide and create a drink. In addition, they can be used to formulate pharmaceuticals that are difficult to digest, cause stomach or oesophageal irritation or which rely on a rapid onset of action, such as analgesics. While the dosage form is highly convenient, manufacturing effervescents can be challenging. A non-hygroscopic, direct compression filler-binder such as galenIQ 721 is needed to produce highly stable tablets. This excipient ensures high content uniformity and facilitates production. It also has a sugar-
A CONVENIENT AND APPEALING DOSAGE FORM Effervescent dosage forms offer distinct advantages compared to traditional tablets. For instance, many patients have problems swallowing tablets. Effervescent powders and tablets offer a more convenient way to deliver medicines or dietary supplements. They
"galenIQ 721 provides high content uniformity and production efficiency for effervescent applications"
like taste profile, a pleasant mouthfeel and can enhance the palatability of effervescent formulations. Available locally from Savannah Fine Chemicals, galenIQ 721 is non-cariogenic, sweet and tooth friendly.
ENHANCED PRODUCT DEVELOPMENT Dr Maj-Britt Cepok, head of business development, pharma, Beneo, comments: “Fizzy tablets are ideally suited to administer a wide range of light- and oxygen-sensitive active ingredients and those which require a large dose. In addition, effervescent preparations are more appealing to consumers than traditional dosage forms. galenIQ 721 helps manufacturers to tap into this market and enhance their development programmes.” •
Beneo – www.beneo.com Savannah Fine Chemicals – www.savannah.co.za
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From basic ingredients to specialty actives for key application areas, such as:
Capsules | Tablets | Liquids | Syrups | Emulsions | Creams | Pastes Johannesburg: +27 11 856 4500 Cape Town: +27 21 830 5306
Durban: +27 31 202 0794 Email: info@savannah.co.za
www.savannah.co.za
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