Newsletter Europe 2009

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NEWSLETTER

SEPTEMBER 2009

TRANSPLANT

DONATION AND TRANSPLANTATION - 2008

COUNCIL OF EUROPE

CONSEIL DE L’EUROPE

2009

Vol. 14. Nº 1

INTERNATIONAL FIGURES ON

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INTERNATIONAL FIGURES ON ORGAN, TISSUE & HEMATOPOIETIC STEM CELL DONATION & TRANSPLANTATION ACTIVITIES. DOCUMENTS PRODUCED BY THE COMMITTEE OF EXPERTS ON THE ORGANISATIONAL ASPECTS OF CO-OPERATION IN ORGAN TRANSPLANTATION (2008)

24/7/09

Editor: Rafael Matesanz NATIONAL DATA PROVIDED BY: AUSTRIA Jacqueline Smits (ET) BELGIUM Jacqueline Smits (ET) BULGARIA Dimitar Brunkov CYPRUS George Kyriakides CZECH REPUBLIC Pavel Brezovský DENMARK Frank Pedersen (SKT) ESTONIA Peeter Dmitriev FINLAND Frank Pedersen (SKT) FRANCE Cristelle Cantrelle Fabienne Pessione GERMANY Jacqueline Smits (ET) GREECE Stratos Chatzixiros HUNGARY Eszter Miskovits IRELAND Freda ONeill ITALY Andrea Ricci LATVIA BaltTransplant LITHUANIA Vita Anulytè LUXEMBURG Jacqueline Smits (ET) MALTA NETHERLANDS Jacqueline Smits (ET) POLAND Jaroslaw Czerwinski PORTUGAL Maria João Aguiar ROMANIA Rosana TURCU SLOVAKIA Ludovit Laca SLOVENIA Jacqueline Smits (ET)

SPAIN Carmen Martin Manuel Serrano David Uruñuela Silvia Martin SWEDEN Frank Pedersen (SKT) UNITED KINGDOM Toyab Hussain (ET) EUROTRANSPLANT Austria, Belgium, Croatia, Germany, Luxemburg, Netherlands, Slovenia (SKT) SCANDIATRANSPLANT Denmark, Finland, Norway, Sweden, Iceland AUSTRALIA Lee Excell CANADA Marianne Tang CROATIA Jacqueline Smits (ET) GEORGIA Gia Tomadze ICELAND Frank Pedersen (SKT) ISRAEL Tamar Ashkenazi MOLDOVA Igor Codreanu NEW ZEALAND Lee Excell NORWAY Frank Pedersen (SKT) SWITZERLAND Franziska Beyeler TURKEY Nuran ERDEN USA www.unos.org ARGENTINA Martín Alejandro Torres Ricardo Rubén Ibar www.grupopuntacana.org

BOLIVIA Ana Claudia Pacheco www.grupopuntacana.org BRASIL www.grupopuntacana.org CHILE www.grupopuntacana.org COLOMBIA Juan Gonzalo López Casas www.grupopuntacana.org COSTA RICA CUBA Juan Alberto Falcón Alvarez Juan Carlos Michelena www.grupopuntacana.org DOMINICANA www.grupopuntacana.org ECUADOR EL SALVADOR Raúl Armando Palomo Escobar GUATEMALA Rudolf A. García-Gallont www.grupopuntacana.org HONDURAS MEXICO Enrique Martínez Gutiérrez Omar Sánchez Ramírez NICARAGUA PANAMA David Crespo PARAGUAY Hugo A. Espinoza C. PERU URUGUAY Inés Alvarez Raul José Mizraji www.grupopuntacana.org VENEZUELA Carmen Luisa Lattuf de Milanés www.grupopuntacana.org GRUPO PUNTA CANA Argentina, Bolivia, Brasil, Chile, Colombia, Costa Rica, Cuba, Dominicana, Ecuador, El Salvador, España, Guatemala, Honduras, México, Nicaragua, Panamá, Paraguay, Perú, Portugal, Puerto Rico, Uruguay y Venezuela www.grupopuntacana.org

Organización Nacional de Trasplantes (ONT) – Spain Rafael Matesanz Beatriz Mahillo Marina Alvarez Foot Note: For the purposes of this Newsletter the following definitions were used: Organ donor: Every potential donor transferred to the operating theatre from whom, at least, one solid organ has been retrieved Multiorgan donor: Every donor from whom, at least, two different solid organs have been retrieved Absolute number: Include all figures corresponding to all donors/patients adults and children Paediatric: Includes only paediatric activity (patients under 15 years old) AULA MÉDICA EDICIONES. Isabel Colbrand, 10-12 - 2ª planta. 28050 Madrid (España) Tel. 91 358 64 78. Fax 91 358 99 79. Depósito legal: M-9.990-1996

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NEWSLETTER TRANSPLANT 2009

CONTENTS • INTERNATIONAL FIGURES

TRANSPLANTATION ACTIVITY. YEAR 2008 ...........................

3

• INTERNATIONAL DATA ON ORGAN DONATION AND TRANSPLANTATION ACTIVITY, WAITING LIST AND FAMILY REFUSALS. YEAR 2008 ...................................................................................................

25

• INTERNATIONAL DATA ON TISSUES AND HEMATOPOIETIC STEM CELL DONATION AND TRANSPLANTATION ACTIVITY. YEAR 2008 .............................................................................................

39

• “THE DECLARATION

49

ON

DONATION

OF ISTANBUL ON

AND

ORGAN TRAFFICKING

AND

TRANSPLANT TOURISM”. YEAR 2008 ...

1

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COUNCIL OF EUROPE

2

Página 2

CONSEIL DE L’EUROPE

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COUNCIL OF EUROPE

CONSEIL DE L’EUROPE

International Figures on Donation and Transplantation Activity.

Year 2008

3

4

26.7

34.2

14.7

25.3

25.7

14.6

11.8

18.6

12.8

21.1

18.7

18.3

20.6

19.1 14.7

18.4

11.2

8.9

1.1

2.9

3.6

18.6 9.8

12:00

18.4

9.7

13.0

23.8

27/7/09

11.8

20.5

16.5

15.2

DECEASED ORGAN DONORS Annual Rate p.m.p. 2008

6.3

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 4

49.4

48.3

45.4

45.7

33.5

38.0

6.2

46.5

29.1

35.6

25.7

43.3

32.1 25.7

31.3

21.2

2.7

10.8

21.5

15.0

23.5

43.8

23.2

83.0 19.4

1.6

10:01

38.2

35.7

58.1

45.5

28.2

24/7/09

33.2

KIDNEY TRANSPLANT –included all the combinations– Annual Rate p.m.p. 2008

15.6

NEWSLETTER TRANSPLANT 14-09:aula medica Página 5

5

6

44.8

44.9

41.9

41.4

26.6

22.6

6.2

21.5

26.9

33.6

25.7

36.4

29.3 23.3

27.3

20.7

16.9

1.1

5.5

5.7

34.0 11.7

10:01

23.0

13.5

23.0

41.5

22.2

37.6

30.7

26.5

24/7/09

30.9

DECEASED DONORS KIDNEY TRANSPLANT Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 6

4.6

3.4

3.5

4.2

25.1

15.4

6.9

2.2

2.0

7.0

2.8 2.4

3.9

0.5

1.5

4.6

0.4

2.3

1.5

5.3

17.4

48.6 7.6

1.6

10:01

15.3

13.5

20.5

14.8

1.7

24/7/09

2.3

LIVING KIDNEY TRANSPLANT Annual Rate p.m.p. 2008

15.6

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 7

7

8

25.8

24.0

15.9

13.7

11.0

21.6

8.0

17.8

14.7

10.9

13.9

9.3 3.6

2.2

6.4

5.3

1.2

2.1

8.4

7.6

10:01

11.9

1.8

1.5

8.0

16.5

15.8

8.8

24/7/09

13.2

LIVER TRANSPLANT Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 8

3.9

6.3

6.0

7.0

1.6

3.8

4.7

5.7

4.5

3.0

7.4

5.7 2.2

4.9

1.6

1.5

1.5

0.4

0.3

0.7

2.7

10:01

2.1

3.6

8.1

4.9

3.9

24/7/09

0.9

HEART TRANSPLANT Heart-Lung TX Included Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 9

9

10

0.4

4.2

3.4

7.7

3.4

5.3

3.3

1.6

14.3

1.9

0.3

0.3

7.0

10:01

2.3

0.6

3.3

6.3

5.6

2.3

24/7/09

0.9

LUNG TRANSPLANT Single + Double Lung Heart-Lung TX Included Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 10

1.3

2.3

1.3

1.7

0.9

2.2

1.6

1.1

3.2

4.1

2.5 0.5

0.5

1.2

0.2

0.4

0.1

1.5

10:01

3.6

2.1

1.1

24/7/09

2.7

PANCREAS TRANSPLANT –included all the combinations– Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Página 11

11

12

0.9

1.9

1.1

1.7

0.7

2.0

1.5

0.8

3.2

3.7

2.2 0.5

0.5

1.2

0.2

0.4

1.5

10:01

2.7

1.9

1.1

24/7/09

2.7

KIDNEY-PANCREAS TRANSPLANT Annual Rate p.m.p. 2008

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Pรกgina 13

5

NEWSLETTER TRANSPLANT 14-09:aula medica

13

14

Population (million inhabitants): 303.9 Deceased Organ D. - included NHBD - (pmp) 7984 (26.3) Deceased Donor Kidney TX (pmp) 10550 (34.7) Living Kidney TX (pmp) 5967 (19.6) Liver TX – included all the combinations - (pmp) 6318 (20.8) Heart TX -included Heart-Lung TX - (pmp) 21630 (7.1) Heart-Lung TX (pmp) 270 (0.1) Lung TX – included all the combinations - (pmp) 14780 (4.9) Pancreas TX – included all the combinations - (pmp) 12730 (4.2)

Population (million inhabitants): 4.3 Deceased Organ D. - included NHBD - (pmp) Deceased Donor Kidney TX (pmp) Living Kidney TX (pmp) Liver TX – included all the combinations - (pmp) Heart TX -included Heart-Lung TX - (pmp) Heart-Lung TX (pmp) Lung TX – included all the combinations - (pmp) Pancreas TX – included all the combinations - (pmp)

310 (7.3) 53 (12.4) 68 (15.9) 240 (5.6) 100 (2.3) 140 (3.2) 40 (0.9)

NEW ZEALAND

10:01

AUSTRALIA

259 (12.1) 459 (21.5) 352 (16.4) 1950 (9.1) 850 (3.9) 50 (0.2) 1150 (5.4) 320 (1.5)

Population (million inhabitants): 21.4 Deceased Organ D. - included NHBD - (pmp) Deceased Donor Kidney TX (pmp) Living Kidney TX (pmp) Liver TX – included all the combinations - (pmp) Heart TX -included Heart-Lung TX - (pmp) Heart-Lung TX (pmp) Lung TX – included all the combinations - (pmp) Pancreas TX – included all the combinations - (pmp)

486 (14.6) 803 (24.1) 474 (14.2) 545 (13.6) 1680 (5.0) 40 (0.1) 1350 (4.1) 85 (82.6)

24/7/09

USA

CANADA

Population (million inhabitants): 33.3 Deceased Organ D. - included NHBD - (pmp) Deceased Donor Kidney TX (pmp) Living Kidney TX (pmp) Liver TX – included all the combinations - (pmp) Heart TX -included Heart-Lung TX - (pmp) Heart-Lung TX (pmp) Lung TX – included all the combinations - (pmp) Pancreas TX – included all the combinations - (pmp)

NEWSLETTER TRANSPLANT 14-09:aula medica Página 14

3.1

0.6

1.8

16.6

9.6

7.1

10:01

19.1

2.1

7.2

24/7/09

13.1

2.2

3.3

0.7

DECEASED ORGAN DONORS Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 15

15

21.8

6.3 5.1 7.3

12.8

16

36.7

5.2

10:01

24.1

8.7

20.5

24/7/09

12.3

14.6

9.6

10.7

KIDNEY TRANSPLANT –included all the combinations– Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Página 16

5.3 15.9

1.1 5.3 0.0 5.1 3.6 3.6

12.1 0.7

13.3 1.3

12.3 –

10:01

34.5 2.1

1.2 4.0

11.0 9.5

24/7/09

18.9 5.2

4.2 4.5

6.4 3.6

0.7 10.0

DECEASED DONORS KIDNEY TRANSPLANT / LIVING KIDNEY TRANSPLANT Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Página 17

17

NEWSLETTER TRANSPLANT 14-09:aula medica

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Pรกgina 18

0.9

2.5

7.0 4.1

4.4

0.4

0.1

0.9

5.7

LIVER TRANSPLANT Annual Rate p.m.p. 2008

24/7/09

18

0.1 0.3

1.7

1.1

2.5

24/7/09 10:01

3.3

0.2

1.1

HEART TRANSPLANT Heart - Lung TX Included Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 19

19

0.3

0.5

0.8

1.2

0.3

LUNG TRANSPLANT Single + Double Lung Heart - Lung TX Included Annual Rate p.m.p. 2008

NEWSLETTER TRANSPLANT 14-09:aula medica

20

24/7/09 10:01 Pรกgina 20

NEWSLETTER TRANSPLANT 14-09:aula medica

24/7/09

10:01

Pรกgina 21

0.1

0.1

1.9

1.8

0.2

KIDNEY - PANCREAS TRANSPLANT Annual Rate p.m.p. 2008

21

NEWSLETTER TRANSPLANT 14-09:aula medica

10:01

Pรกgina 22

1 7

24/7/09

22

NEWSLETTER TRANSPLANT 14-09:aula medica

24/7/09

10:01

Pรกgina 23

23

NEWSLETTER TRANSPLANT 14-09:aula medica

24

24/7/09

10:01

Pรกgina 24

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Página 25

COUNCIL OF EUROPE

CONSEIL DE L’EUROPE

International Data on Organ Donation and Transplantation Activity, Waiting List and Family Refusals.

Year 2008

25

26

172 (20.6) 3 (0.4) 76.7

361 (43.3) 16.1 10 303 (36.4) 303 (36.4) 0 58 (7.0) 12 (1.4)

116 (13.9) 8 1 (0.1) 0 4 (0.5) 1 (0.1)

62 (7.4) 2

3 (0.4) -

119 (14.3) 6 13 (1.6) 106 (12.7) -

34 (4.1) 0 31 (3.7) 3 (0.4)

-

-

Deceased Organ D. - included NHBD - (pmp) NHB Donors (pmp) % Multiorgan donors

KIDNEY TX – included all the combinations - (pmp) % (Living TX/ Total TX) Paediatric <15 years Deceased Donor TX (pmp) -Single TX (pmp) -Double TX (pmp) Living TX (pmp) NHB kidney TX (pmp)

LIVER TX – included all the combinations - (pmp) Paediatric <15 years -Split Liver TX (pmp) -Domino Liver TX(pmp) Living Liver TX (pmp) NHB Liver TX (pmp)

HEART TX -included Heart-Lung transplant- (pmp) Paediatric <15 years

HEART-LUNG Transplants (pmp) Paediatric <15 years

LUNG TX – included all the combinations - (pmp) Paediatric <15 years -Single (pmp) -Double - included Heart-Lung TX - (pmp) NHB – double + single - Lung TX (pmp)

PANCREAS TX – included all the combinations - (pmp) Paediatric <15 years -Kidney - Pancreas TX (pmp) -Pancreas TX Alone (pmp)

SMALL BOWEL TX – included all the combinations - (pmp) Paediatric <15 years -Liver + Small Bowel (pmp) -S. B. TX Alone (pmp)

MULTIVISCERAL (pmp)

-

-

18 (1.7) 0 16 (1.5) 2 (0.2)

82 (7.7) 2 15 (1.4) 67 (6.3) 4 (0.4)

1 (0.1) -

0

0 0 0 0

0 0 0 0

0 0 0 0 0

0 0

3 (0.4) 0

198 (19.1) 1 (0.1) 54.1

-

-

-

-

-

-

-

58 (83.0) 58.6 1 24 (34.0) 24 (34.0) 34 (48.6) -

-

0 0 0 0

26 (2.5) 0 23 (2.2) 3 (0.3)

20 (1.9) 0 6 (0.6) 14 (1.3) 0

0 0

59 (5.7) 1

97 (9.3) 4 0 0 0 0

334 (32.1) 8.1 2 305 (29.3) 297 (28.6) 8 (0.8) 29 (2.8) 1 (0.1)

TRANSPLANTATION

13 (18.6) 100

DONATION

CZECH. R. 10.4

-

-

-

18 (3.3) 0 5 (0.9) 13 (2.4) -

0 0

20 (3.6) 1

44 (8.0) 6 0 0 0 -

196 (35.7) 37.8 10 122 (22.2) 121 (22.0) 1 (0.2) 74 (13.5) -

65 (11.8) 65

DENMARK 5.5

-

-

-

-

-

-

2 (1.5) -

57 (43.8) 5.3 0 54 (41.5) 54 (41.5) 0 3 (2.3) 0

31 (23.8) 0 2

ESTONIA 1.3

-

-

-

12 (2.3) 0 0 12 (2.3) -

0 0

21 (3.9) 3

47 (8.8) 5 0 0 0 -

150 (28.2) 6 10 141 (26.5) 141 (26.5) 0 9 (1.7) -

81 (15.2) 65

FINLAND 5.3

1 (0.0)

13 (0.2)) 7 3 (0.1) 9 (0.1)

81 (1.3) 0 73 (1.1) 8 (0.1)

215 (3.4) 6 53 (0.8) 162 (2.5) 0

19 (0.3) 1

379 (6.0) 13

1011 (15.9) 63 95 (1.5) 11 (0.2) 10 (0.2) 0

2885 (45.4) 7.6 61 2663 (41.9) 2617 (41.1) 46 (0.7) 222 (3.5) 52 (0.8)

1610 (25.3) 47 (0.7) 93.7

FRANCE 63.6

-

-

134 (1.6) 0 121 (1.5) 13 (0.2)

270 (3.3) 4 40 (0.5) 230 (2.8) 0

19 (0.2) 1

382 (4.7) 17

1122 (13.7) 109 89 (1.1) 7 (0.1) 55 (0.7) 0

2753 (33.5) 20.5 94 2188 (26.6) 2169 (26.4) 19 (0.2) 565 (6.9) 0

1199 (14.6) 86.7

GERMANY 82.2

12:00

75 (7.0) 2

9 (1.2) 0 0 0 4 (0.5) 0

19 (2.7) 57.9 1 8 (1.1) 8 (1.1) 0 11 (1.5) 0

8 (1.1) 0 70

CYPRUS 0.7

EUROPEAN UNION COUNTRIES BULGARIA 7.0

27/7/09

230 (21.6) 32 18 (1.7) 0 13 (1.2) 17 (1.6)

487 (45.7) 9.2 18 442 (41.4) 436 (40.9) 6 (0.6) 45 (4.2) 53 (5.0)

274 (25.7) 42 (3.9) 85

BELGIUM 10.7

AUSTRIA 8.3

COUNTRIES Population (million inhabitants)

DONATION AND TRANSPLANTATION ACTIVITY

NEWSLETTER TRANSPLANT 14-09:aula medica Página 26

GREECE 11.0

98 (8.9) 79.6

237 (21.5) 21.5 2 186 (16.9) 186 (16.9) 0 51 (4.6) 0

58 (5.3) 0 0 0 0 0

16 (1.5) 0

0 0

3 (0.3) 0 2 (0.2) 1 (0.1) 0

2 (0.2) 2 (0.2) 0

0 -

0

COUNTRIES Population (million inhabitants)

Deceased Organ D. - included NHBD - (pmp) NHB Donors (pmp) % Multiorgan donors

KIDNEY TX – included all the combinations - (pmp) % (Living TX/ Total TX) Paediatric <15 years Deceased Donor TX (pmp) -Single TX (pmp) -Double TX (pmp) Living TX (pmp) NHB kidney TX (pmp)

LIVER TX – included all the combinations - (pmp) Paediatric <15 years -Split Liver TX (pmp) -Domino Liver TX(pmp) Living Liver TX (pmp) NHB Liver TX (pmp)

HEART TX -included Heart-Lung transplant- (pmp) Paediatric <15 years

HEART-LUNG Transplants (pmp) Paediatric <15 years

LUNG TX – included all the combinations - (pmp) Paediatric <15 years -Single (pmp) -Double - included Heart-Lung TX - (pmp) NHB – double + single - Lung TX (pmp)

PANCREAS TX – included all the combinations - (pmp) Paediatric <15 years -Kidney - Pancreas TX (pmp) -Pancreas TX Alone (pmp)

SMALL BOWEL TX – included all the combinations - (pmp) Paediatric <15 years -Liver + Small Bowel (pmp) -S. B. TX Alone (pmp)

MULTIVISCERAL (pmp)

-

3 (0.1) 1 3 (0.1)

61 (1.1) 47 (0.8) 12 (0.2)

94 (1.6) 31 (0.5) 63 (1.1) -

2 (0.0) -

0

0 0 0 0

1 (0.4) 0 1 (0.4) 0

0 0 0 0 0

0 0

0 0

0 0 0 0 0 0

54 (23.5) 1.9 0 53 (23.0) 53 (23.0) 0 1 (0.4) 20 (8.3)

-

-

4 (1.2) 4 (1.2) -

2 (0.6) 2 (0.6) -

-

5 (1.5) 2

6 (1.8) -

51 (15.0) 9.8 2 46 (13.5) 46 (13.5) 5 (1.5) -

0

0 0 0 0

0 0 0 0

0 0 0 0 0

0 0

0 0

0 0 0 0 0 0

3 (6.2) 0 0 3 (6.2) 3 (6.2) 0 0 0

9 (18.6) 100

LUXEMBOURG 0.5

-

-

-

-

-

-

-

-

-

MALTA 0.4

(0.9) (2.6) (0.7)

(3.4)

-

-

14 (0.9) 0 12 (0.7) 2 (0.1)

56 3 14 42 12

1 (0.1) -

32 (1.6) 4

131 (8.0) 9 8 (0.5) 0 2 (0.1) 29 (1.8)

763 (46.5) 34.0 53.9 352 (21.5) 348 (21.2) 4 (0.2) 411 (25.1) 135 (8.2)

210 (12.8) 91 (5.6) 78.1

0

0 0 0 0

20 (0.5) 0 20 (0.5) 0

11 (0.3) 0 8 (0.2) 3 (0.1) 0

0 0

61 (1.6) 6

245 (6.4) 31 0 0 21 (0.6) 0

810 (21.2) 2.5 31 790 (20.7) 790 (20.7) 0 20 (0.5) 0

427 (11.2) 0 56

NETHERLANDS POLAND 16.4 38.1

0

0 0 0 0

12 (2.7) 12 (2.7) 0

4 (0.9) 0

0 0

326 (5.7) 14

1015 (17.8) 65 92 (1.6) 4 (0.1) 19 (0.3) -

1656 (29.1) 7.4 39 1533 (26.9) 1421 (25.0) 112 (2.0) 123 (2.2) 3 (0.1)

33 (9.7) 30.3

LITHUANIA 3.4

-

-

5 (0.5) 0 5 (0.5) 0

-

-

4 (0.9) -

30 (13.0) 11 (4.8) 0.4

TRANSPLANTATION

1201 (21.1) 3 (0.1) 80.3

DONATION

LATVIA 2.3

10:01

22 (2.2) 2

58 (13.2) 0 -

146 (33.2) 6.9 4 136 (30.9) 129 (29.3) 7 (1.6) 10 (2.3) 0

81 (18.4) 0 58

ITALY 56.9

EUROPEAN UNION COUNTRIES IRELAND 4.4

24/7/09

36 (3.6) 2 0 0 -

259 (25.7) 10.2 7 235 (23.3) 235 (23.3) 0 24 (2.4) -

148 (14.7) 41.2

HUNGARY 10.1

DONATION AND TRANSPLANTATION ACTIVITY

NEWSLETTER TRANSPLANT 14-09:aula medica Página 27

27

28

283 (26.7) 0 73.9

524 (49.4) 9.3 15 475 (44.8) 469 (44.2) 6 (0.6) 49 (4.6) 0

274 (25.8) 14 4 (0.4) 70 (6.6) 5 (0.5) 0

42 (3.9) 3

0 0

4 (0.4) 0 1 (0.1) 3 (0.3) 0

14 (1.3) 0 10 (0.9) 4 (0.4)

0 0 0 0

0

Deceased Organ D. - included NHBD - (pmp) NHB Donors (pmp) % Multiorgan donors

KIDNEY TX – included all the combinations - (pmp) % (Living TX/ Total TX) Paediatric <15 years Deceased Donor TX (pmp) -Single TX (pmp) -Double TX (pmp) Living TX (pmp) NHB kidney TX (pmp)

LIVER TX – included all the combinations - (pmp) Paediatric <15 years -Split Liver TX (pmp) -Domino Liver TX(pmp) Living Liver TX (pmp) NHB Liver TX (pmp)

HEART TX -included Heart-Lung transplant- (pmp) Paediatric <15 years

HEART-LUNG Transplants (pmp) Paediatric <15 years

LUNG TX – included all the combinations - (pmp) Paediatric <15 years -Single (pmp) -Double - included Heart-Lung TX - (pmp) NHB – double + single - Lung TX (pmp)

PANCREAS TX – included all the combinations - (pmp) Paediatric <15 years -Kidney - Pancreas TX (pmp) -Pancreas TX Alone (pmp)

SMALL BOWEL TX – included all the combinations - (pmp) Paediatric <15 years -Liver + Small Bowel (pmp) -S. B. TX Alone (pmp)

MULTIVISCERAL (pmp)

0

0

0 0

0 0 0 0

0 0 0 0 0

0 0

0

0 0 0

0 0 0

0 0 0 0

0 -

26 (4.9) 1

1577 (34.2) 77 (1.7) 84

-

-

-

-

-

6 (3.0) 0

22 (10.9) 0 0 0 0 0

52 (25.7) 0 0 52 (25.7) 52 (25.7) 0 0 0

6 (0.1)

14 (0.3) 8 2 (0.0) 6 (0.1)

104 (2.3) 4 89 (1.9) 15 (0.3)

192 (4.2) 6 90 (1.9) 102 (2.2) 5 (0.1)

4 (0.1) -

292 (6.3) 21

1108 (24.0) 67 22 (0.5) 14 (0.3) 28 (0.6) 14 (0.3)

2229 (48.3) 7.0 62 2073 (44.9) 2050 (44.4) 23 (0.5) 156 (3.4) 105 (2.3)

TRANSPLANTATION

37 (18.3) 81.1

DONATION

SPAIN 46.2

-

-

10 (1.1) 10 (1.1) -

52 (5.6) 27 (2.9) 25 (2.7) -

1 (0.1) -

45 (4.9) 6

146 (15.8) 6 1 (0.1) 7 (0.8) 6 (0.6) -

419 (45.5) 32.5 11 283 (30.7) 277 (30.1) 6 (0.7) 136 (14.8) -

152 (16.5) 85

SWEDEN 9.2

9 (0.1)

14 (0.2) 10 2 (0.0) 3 (0.1)

216 (3.6) 7 162 (2.7) 54 (0.9)

139 (2.3) 6 28 (0.5) 111 (1.8) 12 (0.2)

5 (0.1) 1

127 (2.1) 25

719 (11.9) 106 143 (2.4) 8 (0.1) 36 (0.6) 86 (1.4)

2302 (38.2) 37.1 104 1382 (23.0) 1378 (22.9) 4 (0.1) 920 (15.3) 454 (7.5)

885 (14.7) 264 (4.4) 77.2

U. K. 60.2

-

-

32 (1.5) 1 32 (1.5) -

115 (5.4) 4 11 (0.5) 104 (4.9) 7 (0.3)

5 (0.2) -

85 (3.9) 2

195 (9.1) 6 35 (1.6) 3 (0.1) 4 (0.2)

776 (36.3) 43.25 15 424 (19.8) 422 (19.7) 2 (0.1) 352 (16.4) 43 (2.0)

259 (12.1) 23 (1.1) 81

1 (0.0)

4 (0.1) 0 3 (0.1)

85 (2.6) 64 (1.9) 21 (0.6)

135 (4.1) 31 (0.9) 104 (3.1) 4 (0.1)

4 (0.1) -

168 (5.0) -

545 (13.6) 11 (0.3) 67 (2.0) 16 (0.5)

1204 (36.2) 37.1 730 (21.9) 703 (21.1) 27 (0.8) 474 (14.2) 68 (2.0)

486 (14.6) 40 (1.2) -

CANADA 33.3

-

-

14 (3.2) 0 14 (3.2) -

-

-

20 (4.5) -

65 (14.7) 0 0 0 1 (0.2) 0

158 (35.6) 5.7 4 149 (33.6) 148 (33.4) 1 (0.2) 9 (2.0) 0

83 (18.7) 83.1

CROACIA 4.4

OTHER COUNTRIES AUSTRALIA 21.4

10:01

6 (0.3) 0

12 (2.2) 0 0 0 0

166 (31.3) 12.7 2 145 (27.3) 143 (27) 2 (0.3) 21 (3.9) 0

77 (18.4) 0 48

SLOVENIA 2.0

EUROPEAN UNION COUNTRIES SLOVAKIA 5.3

24/7/09

43 (2.1) 3 0 0 8 (0.4) 0

227 (10.8) 49.3 17 115 (5.5) 114 (5.4) 1 (0.0) 112 (5.3) 2 (0.1)

60 (2.9) 1 (0.0) 60

ROMANIA 21

PORTUGAL 10.6

COUNTRIES Population (million inhabitants)

DONATION AND TRANSPLANTATION ACTIVITY

NEWSLETTER TRANSPLANT 14-09:aula medica Página 28

GEORGIA 4.5

0 0 0

7 (1.6) 100 0 0 0 0 7 (1.6) 0

0 0 0 0 0 0

0 0

0 0

0 0 0 0 0

0 0 0 0

0 0 0 0 0

COUNTRIES Population (million inhabitants)

Deceased Organ D. - included NHBD - (pmp) NHB Donors (pmp) % Multiorgan donors

KIDNEY TX – included all the combinations - (pmp) % (Living TX/ Total TX) Paediatric <15 years Deceased Donor TX (pmp) -Single TX (pmp) -Double TX (pmp) Living TX (pmp) NHB kidney TX (pmp)

LIVER TX – included all the combinations - (pmp) Paediatric <15 years -Split Liver TX (pmp) -Domino Liver TX(pmp) Living Liver TX (pmp) NHB Liver TX (pmp)

HEART TX -included Heart-Lung transplant- (pmp) Paediatric <15 years

HEART-LUNG Transplants (pmp) Paediatric <15 years

LUNG TX – included all the combinations - (pmp) Paediatric <15 years -Single (pmp) -Double - included Heart-Lung TX - (pmp) NHB – double + single - Lung TX (pmp)

PANCREAS TX – included all the combinations - (pmp) Paediatric <15 years -Kidney - Pancreas TX (pmp) -Pancreas TX Alone (pmp)

SMALL BOWEL TX – included all the combinations - (pmp) Paediatric <15 years -Liver + Small Bowel (pmp) -S. B. TX Alone (pmp)

MULTIVISCERAL (pmp)

0

0 0 0 0

0 0 0 0

0 0 0 0 0

0 0

-

-

4 (0.9) 1 4 (0.9) -

14 (3.2) 1 14 (3.2) -

-

10 (2.3) 0

24 (5.6) 1 3 (0.7) 7 (1.6) -

121 (28.3) 56.2 2 53 (12.4) 68 (15.9) 4 (0.9)

-

-

10 (2.1) 0 9 (1.9) 1 (0.2)

30 (6.3) 0 1 (0.2) 29 (6.0) -

3 (0.6) 0

39 (8.1) 1

79 (16.5) 7 3 (0.6) 0 0 -

278 (58.1) 35.3 3 180 (37.6) 178 (37.1) 2 (0.5) 98 (20.5) -

0

1 (0.1) 0 1 (0.1)

17 (2.2) 15 (2.0) 2 (0.2)

40 (5.3) 1 6 (0.8) 34 (4.5) -

0 -

29 (3.8) -

83 (11.0) 8 8 (1.0) 4 (0.5) 12 (1.6) -

286 (38.0) 40.6 9 170 (22.6) 169 (22.5) 1 (0.1) 116 (15.4) 0

90 (11.8) 0 90

SWITZERLAND 7.5

4 (0.1)

3 (0.0) 0 0 3 (0.0)

10 (0.1) 0 3 (0.0) 7 (0.1)

1 (0.0) 0 0 1 (0.0) 0

1 (0.0)

51 (0.7) 8

602 (8.4) 8 (0.1) 0 390 (5.4) 0

1662 (23.2) 75.1 414 (5.7) 412 (5.7) 2 (0.0) 1248 (17.4) 6 (0.1)

262 (3.6) 3 (0.0) 96.9

TURKEY 71.5

-

185 (0.6) 93 185 (0.6)

1273 (4.2) 69 837 (2.8) 436 (1.4)

1478 (4.9) 45 -

27 (0.1) 6

2163 (7.1) 365

6318 (20.8) 613 249 (0.8) -

16517 (54.4) 36.1 773 10550 (34.7) 5967 (19.6) -

7984 (26.3) -

USA 303.9

-

1 (0.1) 1 1 (0.1) 1 (0.1)

11 (1.5) 11 (1.5) -

51 (7.0) 1 35 (4.8) 16 (2.2) -

1 (0.1) -

0 0

0 0 0 0 0 0

0 0 0 0 0 0 0 0

98 (20.5) 90

NORWAY 4.8

-

-

-

-

-

20 (2.7) 3

56 (7.6) 8 1 (0.1) 2 (0.3) -

142 (19.4) 39.4 17 86 (11.7) 85 (11.6) 1 (0.1) 56 (7.6) -

31 (7.3) 2 (0.5) 81

NEW ZEALAND 4.3

10:01

-

0 0 0

DONATION

TRANSPLANTATION

72 (9.8) 79.2

MOLDOVA 3.8

OTHER COUNTRIES ISRAEL 7.3

24/7/09

5 (15.6) 100 5 (15.6) -

5 (15.6) 100 5 (15.6) -

2 (6.3) 100

ICELAND 0.3

DONATION AND TRANSPLANTATION ACTIVITY

NEWSLETTER TRANSPLANT 14-09:aula medica Página 29

29

30

519 (13.1) 57.6

960 (24.1) 21.6 70 753 (18.9) 746 (18.7) 7 (0.2) 207 (5.2) -

280 (7.0) 65 12 (0.3) 33 (0.8) -

100 (2.5) 8

3 (0.1) 1

32 (0.8) 1 16 (0.4) 16 (0.4) -

85 (2.1) 77 (1.9) 8 (0.2)

8 (0.2) 6 2 (0.1) 5 (0.1)

1 (0.0)

Deceased Organ D. - included NHBD - (pmp) NHB Donors (pmp) % Multiorgan donors

KIDNEY TX – included all the combinations - (pmp) % (Living TX/ Total TX) Paediatric <15 years Deceased Donor TX (pmp) -Single TX (pmp) -Double TX (pmp) Living TX (pmp) NHB kidney TX (pmp)

LIVER TX – included all the combinations - (pmp) Paediatric <15 years -Split Liver TX (pmp) -Domino Liver TX(pmp) Living Liver TX (pmp) NHB Liver TX (pmp)

HEART TX -included Heart-Lung transplant- (pmp) Paediatric <15 years

HEART-LUNG Transplants (pmp) Paediatric <15 years

LUNG TX – included all the combinations - (pmp) Paediatric <15 years -Single (pmp) -Double - included Heart-Lung TX - (pmp) NHB – double + single - Lung TX (pmp)

PANCREAS TX – included all the combinations - (pmp) Paediatric <15 years -Kidney - Pancreas TX (pmp) -Pancreas TX Alone (pmp)

SMALL BOWEL TX – included all the combinations - (pmp) Paediatric <15 years -Liver + Small Bowel (pmp) -S. B. TX Alone (pmp)

MULTIVISCERAL (pmp)

-

-

-

-

-

-

-

32 (0.2) -

53 (0.3) -

-

200 (1.1) -

463 (9.6) -

-

-

-

9 (0.5) -

-

19 (1.1) -

74 (4.4) -

206 (12.3) 206 (12.3) -

-

-

5 (0.1) -

14 (0.3) -

-

83 (1.7) -

198 (4.1) -

705 (14.6) 641 (13.3) 64 (1.3) -

TRANSPLANTATION

119 (7.1) -

-

-

-

-

-

-

-

-

-

COSTA RICA 4.5

-

-

1 (0.1) 1 (0.1) -

-

-

3 (0.3) -

28 (2.5) 2 -

144 (12.8) 5.6 1 136 (12.1) 136 (12.1) 8 (0.7) -

186 (16.6) 26.8

CUBA 11.2

-

-

-

-

-

-

1 (0.1) -

7 (0.7) 93.1 7 (0.7) 95 (10.0) -

102 (10.7) -

DOMINICANA 9.5

-

-

-

-

-

-

-

-

-

ECUADOR 13.6

-

0 0 -

0 0 -

0 0 -

0 0

0 0

0 0 -

29 (5.1) 100 0 0 29 (5.1) -

0 -

EL SALVADOR 5.7

10:01

-

1053 (5.7) -

3780 (20.5) 2033 (11.0) 1747 (9.5) -

COLOMBIA 48.2

DONATION

CHILE 16.8

LATINAMERICAN COUNTRIES

1331 (7.2) -

BRASIL 184.8

24/7/09

-

79 (8.7) 51.9 38 (4.2) 41 (4.5) -

20 (2.2) -

BOLIVIA 9.1

ARGENTINA 39.7

COUNTRIES Population (million inhabitants)

DONATION AND TRANSPLANTATION ACTIVITY

NEWSLETTER TRANSPLANT 14-09:aula medica Página 30

GUATEMALA 13.5

7 (0.6) -

85 (6.3) 83.5 14 (1.1) 12 (0.9) 1 (0.1) 71 (5.3) -

-

-

-

-

-

-

COUNTRIES Population (million inhabitants)

Deceased Organ D. - included NHBD - (pmp) NHB Donors (pmp) % Multiorgan donors

KIDNEY TX – included all the combinations - (pmp) % (Living TX/ Total TX) Paediatric <15 years Deceased Donor TX (pmp) -Single TX (pmp) -Double TX (pmp) Living TX (pmp) NHB kidney TX (pmp)

LIVER TX – included all the combinations - (pmp) Paediatric <15 years -Split Liver TX (pmp) -Domino Liver TX(pmp) Living Liver TX (pmp) NHB Liver TX (pmp)

HEART TX -included Heart-Lung transplant- (pmp) Paediatric <15 years

HEART-LUNG Transplants (pmp) Paediatric <15 years

LUNG TX – included all the combinations - (pmp) Paediatric <15 years -Single (pmp) -Double - included Heart-Lung TX - (pmp) NHB – double + single - Lung TX (pmp)

PANCREAS TX – included all the combinations - (pmp) Paediatric <15 years -Kidney - Pancreas TX (pmp) -Pancreas TX Alone (pmp)

SMALL BOWEL TX – included all the combinations - (pmp) Paediatric <15 years -Liver + Small Bowel (pmp) -S. B. TX Alone (pmp)

MULTIVISCERAL (pmp)

-

-

-

-

-

-

-

-

-

-

-

-

24 (7.3) 50.0 0 12 (3.6) 12 (3.6) 0 12 (3.6) 0

1 (0.2)

1 (0.2) 0 0 0

0 0 0 0

0 0 0 0 0

0 0

1 (0.2) 0

0 0 0 0 0 0

27 (5.2) 77.8 0 6 (1.2) 6 (1.2) 0 21 (4.0) 0

-

-

-

-

-

-

-

-

-

PERU 28.8

-

-

6 (1.8) 0 6 (1.8) -

4 (1.2) -

-

11 (3.3) 0

3 (0.9) -

114 (34.5) 7 (2.1) -

121 (36.7)

63 (19.1) 0 80.9

URUGUAY 3.3

0

0 0 0 0

0 0 0 0

0 0 0 0 0

0 0

0 0

10 (0.4) 5 2 (0.1) 0 8 (0.3) 0

278 (9.6) 36.0 29 178 (6.4) 178 (6.4) 0 100 (3.6) 0

93 (3.3) 0 2

VENEZUELA 27.9

-

-

1 (0.0) 1 (0.0)

1 (0.0) 1 (0.0) -

-

-

-

-

11 (2.1) 0 0

PARAGUAY 5.2

-

-

-

-

-

14 (0.1) 2

96 (0.9) 8 0 8 (0.1) 0

2260 (21.8) 75.14 255 562 (5.3) 556 (5.2) 6 (0.1) 1698 (15.9) -

6 (1.8) 0 0

PANAMA 3.3

10:01

-

-

DONATION

NICARAGUA 5.7

TRANSPLANTATION

332 (3.1) 33.6

MEXICO 106.7

LATINAMERICAN COUNTRIES

24/7/09

-

-

-

HONDURAS 7.5

DONATION AND TRANSPLANTATION ACTIVITY

NEWSLETTER TRANSPLANT 14-09:aula medica Página 31

31

32 365 883 39 -

149 113 31

81 59 7

128 62 13

29 37 -

-

KIDNEY Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 ESRD on dialysis treatment during 2008

LIVER Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

HEART Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

LUNG Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

PANCREAS Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

SMALL BOWEL Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 -

24 27 1

116 76 6

-

-

-

-

-

-

-

-

1 29 111 3 -

CYPRUS 0.7

1 0 0 0

1 31 39 0

1 40 53 10

2 96 77 14

2 110 56 11

7 443 546 12 -

CZECH. R. 10.4

0 -

0 -

1 38 52 7

2 22 17 1

1 43 36 4

4 206 489 44 -

DENMARK 5.5

-

-

-

-

1 2 3 0

1 54 63 4 300

ESTONIA 1.3

0 -

0 -

1 20 6 2

1 28 10 1

1 38 7 1

1 251 398 14 -

FINLAND 5.3

5 19 25 1

11 115 154 5

13 278 176 29

26 508 300 66

24 1371 669 107

44 3671 6859 201 -

FRANCE 63.6

-

197 263 22

442 593 112

719 873 149

1649 1948 339

3064 8003 267

GERMANY 82.2

10:01

1 8 45 8

2 7 52 5

35 811 2855

BULGARIA 7.0

EUROPEAN UNION COUNTRIES

24/7/09

110 43 19

302 189 44

455 813 18 -

BELGIUM 10.7

AUSTRIA 8.3

COUNTRIES Population (million inhabitants)

WAITING LIST

NEWSLETTER TRANSPLANT 14-09:aula medica Página 32

GREECE 11.0

4 225 880 15 -

2 84 67 12

1 17 24 1

1 5 2 1

0 -

0 -

COUNTRIES Population (million inhabitants)

KIDNEY Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 ESRD on dialysis treatment during 2008

LIVER Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

HEART Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

LUNG Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

PANCREAS Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

SMALL BOWEL Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 -

2 4 16 1

0 14 5 2

0 -

1 11 23 0

1 -

3 7 1 20

13 70 6 253

13 215 329 69

19 517 730 126

22 1282 1504 173

43 2609 7214 160 -

ITALY 56.9

0 0 0 0

1 2 2 0

0 0 0 0

1 2 7 1

0 0 0 0

1 37 300 10 -

LATVIA 2.3

-

1 12 11 -

2 1 3 -

2 9 33 5

2 8 24 2

2 87 252 8 -

LITHUANIA 3.4

-

0 -

0 -

0 -

0 -

5 10 -

LUXEMBOURG 0.5

-

-

-

-

-

-

MALTA 0.4

-

21 30 1

113 185 28

64 54 12

143 118 22

870 952 77 -

0 0 0 0

4 30 15 0

1 21 20 5

4 155 204 41

5 274 115 35

18 1030 1479 67 16000

NETHERLANDS POLAND 16.4 38.1

10:01

1 -

1 54 14 5

1 209 504 19 -

IRELAND 4.4

EUROPEAN UNION COUNTRIES

24/7/09

2 25 11 7

1 130 67 15

4 255 685 28 4728

HUNGARY 10.1

WAITING LIST

NEWSLETTER TRANSPLANT 14-09:aula medica Página 33

33

34 8 2275 9814

3 -

4 -

1 -

1 13 27 -

0 0 0 0

KIDNEY Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 ESRD on dialysis treatment during 2008

LIVER Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

HEART Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

LUNG Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

PANCREAS Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

SMALL BOWEL Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 0 0 0 0

3 35 90 10

2 8 22 2

0 -

0 -

0 -

-

0 1 -

0 -

12 17 2

28 13 4

44 72 4

SLOVENIA 2.0

3 19 27 3

11 211 83 5

9 413 175 19

18 453 90 29

26 2144 691 158

44 4301 22609

SPAIN 46.2

1 -

3 18 24 1

2 45 11 4

3 53 19 8

3 128 46 12

4 292 452 28 -

SWEDEN 9.2

3 23 8 3

8 383 459 15

5 200 243 56

7 201 115 23

8 920 356 88

24 3277 9498 277 -

U. K. 60.2

-

2 28 -

5 137 -

5 83 -

8 170 -

22 1298 -

8 0

147 5

282 44

137 16

587 16

3277 62 -

CANADA 33.3

-

10 3 1

0 -

44 18 7

101 61 23

164 349 5

CROACIA 4.4

OTHER COUNTRIES AUSTRALIA 21.4

10:01

2 25 12 -

2 14 12 0

4 190 507 86 -

SLOVAKIA 5.3

EUROPEAN UNION COUNTRIES

24/7/09

2 26 107 12

1 177 350 50

5 490 2085 26 6550

ROMANIA 21.0

PORTUGAL 10.6

COUNTRIES Population (million inhabitants)

WAITING LIST

NEWSLETTER TRANSPLANT 14-09:aula medica Página 34

GEORGIA 4.5

2 1500

-

-

-

-

-

COUNTRIES Population (million inhabitants)

KIDNEY Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 ESRD on dialysis treatment during 2008

LIVER Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

HEART Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

LUNG Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

PANCREAS Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

SMALL BOWEL Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 0 -

0 -

0 -

1 -

3 9 20 -

2 63 46 26

0 0 0 0

0 0 0 0

0 0 0 0

0 0 0 0

0 0 0 0

1 20 140 15 360

-

1 4 -

1 5 -

1 7 -

1 24 -

3 570 -

NEW ZEALAND 4.3

0 -

1 20 21 1

1 36 35 11

1 29 4 0

1 74 7 0

1 183 228 7 -

NORWAY 4.8

1 1 1 0

2 14 16 2

2 60 46 7

3 36 19 8

3 143 108 25

6 425 758 23 -

SWITZERLAND 7.5

2 3 0 -

5 86 -

1 2 -

16 264 -

25 1257 -

44 11500 50554

TURKEY 71.5

18 267 211 25

141 2483 3779 243

67 2003 1962 231 -

131 3383 2784 370

117 11176 16421 1509

250 34057 84831 4581 -

USA 303.9

10:01

3 53 120 15

3 108 131 19

6 300 598 18 -

MOLDOVA 3.8

OTHER COUNTRIES ISRAEL 7.3

24/7/09

0 -

0 -

1 -

ICELAND 0.3

WAITING LIST

NEWSLETTER TRANSPLANT 14-09:aula medica Página 35

35

36 51 1675 4747 237 25164

16 485 482 99

25 158 109 43

9 76 88 17

8 94 80 8

3 11 3 0

KIDNEY Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 ESRD on dialysis treatment during 2008

LIVER Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

HEART Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

LUNG Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

PANCREAS Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

SMALL BOWEL Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 -

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

COLOMBIA 48.2

-

-

-

-

-

-

COSTA RICA 4.5

-

2 1 0 0

1 5 5 0

1 3 0 0

3 36 8 0

9 100 1000 2442

CUBA 11.2

-

-

-

-

-

1250

-

-

-

-

-

-

DOMINICANA ECUADOR 9.5 13.6

0 -

0 -

0 -

0 -

0 -

29 -

EL SALVADOR 5.7

10:01

-

-

-

CHILE 16.8

LATINAMERICAN COUNTRIES BRASIL 184.8

24/7/09

-

-

-

BOLIVIA 9.1

ARGENTINA 39.7

COUNTRIES Population (million inhabitants)

WAITING LIST

NEWSLETTER TRANSPLANT 14-09:aula medica Página 36

GUATEMALA 13.5

-

-

-

-

-

-

COUNTRIES Population (million inhabitants)

KIDNEY Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 ESRD on dialysis treatment during 2008

LIVER Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

HEART Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

LUNG Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

PANCREAS Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008

SMALL BOWEL Nº TX CENTRES Patients admitted to the WL during 2008 Patients awaiting for a TX by 2008, 31st Dec Patients dead while on the WL during 2008 -

-

-

-

10 6 21 0

6 0 3 0

-

-

-

-

-

-

NICARAGUA 5.7

-

-

-

-

-

1 30 135 20 967

PANAMA 3.3

0 -

0 -

0 -

3 2 1 1

0 -

4 49 3 2 704

PARAGUAY 5.2

-

-

-

-

-

-

PERU 28.8

-

1 6 11 1

-

2 12 29 6

-

4 122 403 13 2950

URUGUAY 3.3

0 0 0 0

0 0 0 0

0 0 0 0

0 0 0 0

1 6 12 2

10 385 928 19 -

VENEZUELA 27.9

10:01

35 45 60 6

49 221 341 45

197 4171 5562 52 -

MEXICO 106.7

LATINAMERICAN COUNTRIES

24/7/09

-

-

-

HONDURAS 7.5

WAITING LIST

NEWSLETTER TRANSPLANT 14-09:aula medica Página 37

37

38 GREECE 11.0 158 53 (33.5)

PORTUGAL 10.6 -

GEORGIA 4.5 0 0

ARGENTINA 39.7 1178 569 (48.3) GUATEMALA 13.5 -

Number of interviews, asking for consent to donation Number of family refusals (%)

COUNTRIES Population (million inhabitants)

Number of interviews, asking for consent to donation Number of family refusals (%)

COUNTRIES Population (million inhabitants)

Number of interviews, asking for consent to donation Number of family refusals (%)

COUNTRIES Population (million inhabitants)

Number of interviews, asking for consent to donation Number of family refusals (%)

COUNTRIES Population (million inhabitants)

Number of interviews, asking for consent to donation Number of family refusals (%)

COUNTRIES Population (million inhabitants)

Number of interviews, asking for consent to donation Number of family refusals (%)

-

-

HONDURAS 7.5

BOLIVIA 9.1

-

ICELAND 0.3

24 13 (54.2)

LATVIA 2.3

-

CZECH. R. 10.4

155 83 (53.6)

ISRAEL 7.3 0 0

MOLDOVA 3.8

-

951 -

MEXICO 106.7

BRASIL 184.8

-

- (40.1)

-

-

-

1551 591 (38.1)

U. K. 60.2

-

33 15 (45.5)

PARAGUAY 5.2

213 57 (27.0)

CUBA 11.2

143 42 (29.4)

-

(43.8) PERU 28.8 -

-

720 458 (63.6)

TURKEY 71.5

-

CANADA 33.3

85 28 (33.0)

URUGUAY 3.3

-

DOMINICANA ECUADOR 9.5 13.6

160 56 (35.0)

-

GERMANY 82.2

497 54 (10.9)

NETHERLANDS POLAND 16.4 38.1

976

FRANCE 63.6

197 50 (25.4)

VENEZUELA 27.9

-

EL SALVADOR 5.7

-

USA 303.9

-

CROACIA 4.4

OTHER COUNTRIES AUSTRALIA 21.4

0 0

MALTA 0.4

-

FINLAND 5.3

SWITZERLAND 7.5

LUXEMBOURG 0.5

50 16 (32.0)

ESTONIA 1.3

NORWAY 4.8

COSTA RICA 4.5

PANAMA 3.3

COLOMBIA 48.2

NICARAGUA 5.7

- (33.0)

CHILE 16.8

-

SWEDEN 9.2

NEW ZEALAND 4.3

1577 343 (17.9)

SPAIN 46.2

OTHER COUNTRIES

-

SLOVENIA 2.0

LATINAMERICAN COUNTRIES

-

SLOVAKIA 5.3

61 19 (31.2)

LITHUANIA 3.4

-

DENMARK 5.5

10:01

94 27 (28.7)

2299 749 (32.6)

ITALY 56.9

-

CYPRUS 0.7

EUROPEAN UNION COUNTRIES

105 24 (22.9)

IRELAND 4.4

10 8 (80.0)

BULGARIA 7.0

EUROPEAN UNION COUNTRIES

24/7/09

ROMANIA 21

148 11 (7.4)

HUNGARY 10.1

-

BELGIUM 10.7

AUSTRIA 8.3

COUNTRIES Population (million inhabitants)

FAMILY REFUSALS

NEWSLETTER TRANSPLANT 14-09:aula medica Pรกgina 38

NEWSLETTER TRANSPLANT 14-09:aula medica

24/7/09

10:01

Página 39

COUNCIL OF EUROPE

CONSEIL DE L’EUROPE

International Data on Tissue and Hematopoietic Stem Cell Donation and Transplantation Activity.

Year 2008

39

NEWSLETTER TRANSPLANT 14-09:aula medica

24/7/09

10:01

Página 40

TISSUE & HEMATOPOIETIC STEM CELL NATIONAL DATA PROVIDED BY: AUSTRIA Johann Kurz BELGIUM Muylle Ludo BULGARIA Dimitar Brunkow CYPRUS CZECH REPUBLIC Pavel Brˇezovský Jana Sikorová Eva Krˇemenová DENMARK ESTONIA FINLAND FRANCE Arnaud De Guerra Fenzi Teskrat GERMANY Johanna Strobel Ralf Tönjes GREECE Athina Gompou HUNGARY IRELAND ITALY Fiorenza Bariani Letizia Lombardini Simonetta Pupella Giulia Scaravelli LATVIA Anita Daugavvanaga LITHUANIA Dainora Medeisiene LUXEMBURG MALTA NETHERLANDS POLAND Artur Kaminski PORTUGAL Margarida Amil Diaz Carlos Calhaz Jorge ROMANIA Rosana Turcu SLOVAKIA Jan Koller

SLOVENIA Gorazd Cˇebulc Andrijana Tivadar Sabina Lobe SPAIN Rosario Marazuela Marina Alvarez SWEDEN Camilla Olofsson UNITED KINGDOM Sandy Mather Trish Davies

AUSTRALIA CANADA CROATIA Mirela Busic GEORGIA ICELAND ISRAEL MACEDONIA NEW ZEALAND NORWAY Vibeke Dalen SWITZERLAND TURKEY Zeynep Coskun USA

ARGENTINA Martín Alejandro Torres Ricardo Rubén Ibar www.grupopuntacana.org BOLIVIA BRASIL www.grupopuntacana.org CHILE COLOMBIA Juan Gonzalo López Casas COSTA RICA CUBA Juan Alberto Falcón Alvarez Juan Carlos Michelena www.grupopuntacana.org DOMINICANA www.grupopuntacana.org ECUADOR EL SALVADOR Raúl Armando Palomo Escobar GUATEMALA HONDURAS MEXICO Enrique Martínez Gutiérrez Omar Sánchez Ramírez NICARAGUA PANAMA David Crespo PARAGUAY Hugo A. Espinoza C. PERU URUGUAY Inés Alvarez Raúl José Mizraji www.grupopuntacana.org VENEZUELA Carmen Luisa Lattuf de Milanés www.grupopuntacana.org

Data recorded & prepared by: EUROCET - European Registry of Competent Authorities for Tissues and Cells - Team (www.eurocet.org)

40

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

N° of donation PMP donation N° of tissues retrieved - cm2 N° of tissues retrieved - units N° of transplants N° of transplants - cm2 transplanted PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

CORNEA

SKIN

CARDIAC TISSUE

BLOOD VESSELS

MUSCULOSKELETAL

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

35 4,6 35 12 1,6

543 71,1 497 375 49,1

0 0

0

0 0

1.024 98,6 1.024 1.012 97,5

803 77,4 805 1.918 184,8

11 1,1 18 9 0,9

68 6,6 120 92 8,9

3,9

41

39 3,8 159.600

630 60,7 1.262 855 82,4

CZECH REPUBLIC DENMARK 10.381.130 5.475.791 2008 NO DATA

ESTONIA 1.338.617 NO DATA

FINLAND 5.296.826 NO DATA

2.700 1.619 25,4

65 1,0 144 212 3,3

257 4,0 2.566 566 8,9

173 2,7 488 163 2,6

313.793

119 1,9 253.187

8.156 3.790 59,4

FRANCE 63.753.140 2008

GREECE 11.214.992 2008

21 0,3

53 0,6

1.346 16,4

361 4,4

30.542 371,5

5.497 66,9

15 0,2

76 0,9

15 0,2

32 0,4

6,1

499

2.684 32,6

3.553 43,2

GERMANY 82.221.808 2008

OTHER

34 4,1

1.932 231,9

266 31,9

CYPRUS 794.580 NO DATA

10:01

0

12,3

128,1

5 0,7

140 18,3 140 126 16,5

BULGARIA 7.640.238 2008

EUROPEAN UNION COUNTRIES

5 94

BELGIUM 10.660.770 2008

1.067

566 67,9

AUSTRIA 8.331.930 2008

24/7/09

PLACENTA\AMNIOTIC N° of donation MEMBRAN PMP donation N° of tissues retrieved N° of transplants PMP transplants

TYPE OF DATA

TYPE OF TISSUE

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON TISSUES

NEWSLETTER TRANSPLANT 14-09:aula medica Página 41

41

42 0 0 0

0 0

PLACENTA\AMNIOTIC N° of donation MEMBRAN PMP donation N° of tissues retrieved N° of transplants PMP transplants

OTHER

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

237 4 252 1.120 18,8

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

MUSCULOSKELETAL

747 12,5 1.013 226 3,8 26 11,4 102 102 44,9

2.779 46,6 7.042 5.663 95,1

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

BLOOD VESSELS

6 1,8 6 56 16,6

94 27,9 110 78 23,2

0 0

0

9 2,7 12 3 0,9

71 1,9 71 759 19,9

413 10,8 3.424 8.961 235,1

5 0,1 6 3 0,1

157 4,1 298 161 4,2

61 5,7 61 69 6,5

41 3,9 41 6 0,6

9 0,8 9 0 0

45 4,2 45 5 0,5

0,7

7

5 0,5 2.055

451 42,5 976 747 70,4

PORTUGAL 10.617.575 2008

0 0

0

0 0

0

339 15,7 304 287 13,3

0 0

0

0 0

0

1

21

23 1,1 35.660

14 0,7 28 23 1,1

ROMANIA 21.528.627 2008

10:01

230 3,9 459 144 2,4

26

14.582

10 0,3 5.572

393 10,3 760 473 12,4

POLAND 38.115.641 2008

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

NETHERLANDS 16.404.282 NO DATA

CARDIAC TISSUE

MALTA 410.584 NO DATA

24/7/09

1.550

326 5,5 1.046.913

15 4,5 30 30 8,9

LUXEMBOURG 483.799 NO DATA

N° of donation PMP donation N° of tissues retrieved - cm2 N° of tissues retrieved - units N° of transplants N° of transplants - cm2 transplanted PMP transplants

26 11,4 48 48 21,1

LITHUANIA 3.366.357 2008

SKIN

6.005 100,8 11.883 4.815 80,8

LATVIA 2.270.894 2008

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

ITALY 59.578.359 2008

EUROPEAN UNION COUNTRIES

CORNEA

IRELAND 4.419.859 NO DATA

TYPE OF DATA

HUNGARY 10.045.000 NO DATA

TYPE OF TISSUE

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON TISSUES

NEWSLETTER TRANSPLANT 14-09:aula medica Página 42

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

MUSCULOSKELETAL

PLACENTA\AMNIOTIC N° of donation MEMBRAN PMP donation N° of tissues retrieved N° of transplants PMP transplants

3 0,6 4 1 0,2

66 32,6 68 6 3

2 1 18 0 0

79 119 2,6

66 1,5 1.821 990 21,9

1.822 40,2 10.832 6.154 135,9

221 4,9 329 98 2,2

54 2 116 52 2,8

143 15,6 255 115 12,5

7.601

2

5.412

178

1.311

957

4.523

22 5

265 59,7 284 261 58,8

23,7

23 105

9 2

41 9,2 82 64 14,4

UNITED KINGDOM CROATIA 61.270.283 4.435.383 2008 2008

ICELAND 314.321 NO DATA

MACEDONIA 2.045.179 NO DATA

NORWAY 4.737.171 NO DATA

OTHER COUNTRIES SWITZERLAND 7.591.414 NO DATA

1.720 24,4 1.720 1.565 22,2

TURKEY 70.586.256 NO DATA

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

23 4,3 6.026 87 16,1

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

BLOOD VESSELS

267 5,9 240 123 2,7

800

2 0,2 3.900

305 33,2 603 462 50,3

SWEDEN 9.182.927 2008

10:01

12 2,2 21 9 1,7

1,2

53

191 4,2 583.484

2.813 62,1 5.493 2.762 61

SPAIN 45.283.259 2008

24/7/09

OTHER

220 40,7 671 210 38,9

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

0

0

CARDIAC TISSUE

5 2,5 5

N° of donation PMP donation N° of tissues retrieved - cm2 N° of tissues retrieved - units N° of transplants N° of transplants - cm2 transplanted PMP transplants

SKIN

56 27,6 111 95 46,9

SLOVENIA 2.025.866 2008

EUROPEAN UNION COUNTRIES

5 0,9 14.781

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

CORNEA

154 28,5 225 189 35

TYPE OF DATA

SLOVAKIA 5.400.998 2008

TYPE OF TISSUE

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON TISSUES

NEWSLETTER TRANSPLANT 14-09:aula medica Página 43

43

44

N° of donation PMP donation N° of tissues retrieved - cm2 N° of tissues retrieved - units N° of transplants N° of transplants - cm2 transplanted PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

SKIN

CARDIAC TISSUE

BLOOD VESSELS

MUSCULOSKELETAL

OTHER

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

769 19,3 6.474 5.894 148,3

10 0,3 3 0 0,1 34 3,0 34 31 2,7

30 9 44 137 41,2

28 8,4 59 33 10

7 2,1 20 6 1,8

65 2,3 118 111 4

VENEZUELA 27.930.000 2008

10:01

291 7,3 613 532 13,4

6,9

101 30,6 196 133 40,3

1

2676 25,2

17 3,2 1 33 6,3

URUGUAY 3.323.906 2008

23

115 12,1

750 7,0

PARAGUAY 5.163.200 2008

41

56 3,5

3 0,3

MEXICO 106.680.000 2008

27 8,1 1.060

13.352 72,6

578 51,6 1156 560 50,0

DOMINICANA 9.500.000 2008

45 1,1 51.878

1.519 38,2 1.519 1.017 25,6

CUBA 11.236.790 2008

24/7/09

PLACENTA\AMNIOTIC N° of donation MEMBRAN PMP donation N° of tissues retrieved N° of transplants PMP transplants

N° of donation PMP donation N° of tissues retrieved N° of transplants PMP transplants

CORNEA

CHILE 16.800.000 2008

LATINAMERICAN COUNTRIES BRASIL 184.800.000 2008

TYPE OF DATA

ARGENTINA 39.745.593 2008

TYPE OF TISSUE

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON TISSUES

NEWSLETTER TRANSPLANT 14-09:aula medica Página 44

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

151 30 1 120 0

18,1 3,6 0,1 14,4

151 30 1 120

151 30 1 120

25 5 0 20 0

2,6

3,3 0,7

15

15

5

10 5

25 5 0 20

CYPRUS 794.580 NO DATA

1.612

24,7

222

34

256

130,6

1.356

627

29

1.086

CZECH REPUBLIC DENMARK 10.381.130 5.475.791 2008 NO DATA

ESTONIA 1.338.617 NO DATA

FINLAND 5.296.826 NO DATA

4.423 452 246 3.725 0

23,1 6,9 3,9 12,4

841 191 237 413

631 246 9 376

6.003 889 15 5.099 0

24,8 0 0,2 24,7

2.042 0 15 2.027

37,4

46,1 1.472 437 246 789

48,2 10,8

3.961 889 0 3.072

1.093 1.093

10.228 1.093 4.457 4.678

10.794 5.704

16.498

GERMANY 82.221.808 2008

46,3 0,2

2.936

2.951 15

FRANCE 63.753.140 2008

Total N. of transplants

PMP transplants - Allogenic

N° of transplants - Unrelated

N° of transplants - Related

N° of transplants - Allogenic

PMP transplants - Autologous

15

15

5

10 5

25 5 0 20

1.264 5 1.239 20

BULGARIA 7.640.238 2008

EUROPEAN UNION COUNTRIES BELGIUM 10.660.770 NO DATA

10:01

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

TYPE OF HPC CELLS

AUSTRIA 8.331.930 2008

24/7/09

N° of transplants - Autologous

N° of donations - Unrelated

N° of donations - Related

N° of donations - Allogenic

N° of donations - Autologous

TYPE OF DATA

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON HPC CELLS

NEWSLETTER TRANSPLANT 14-09:aula medica Página 45

45

46

Total N. of transplants

PMP transplants - Allogenic

N° of transplants - Unrelated

N° of transplants - Related

N° of transplants - Allogenic

PMP transplants - Autologous

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

61 8 10 43 0

5,4 0,7 0,9 3,8

61 8 10 43

61 8 10 43

0

0

4.275 519 126 3.598 32

23,9 7,7 2,1 13,8 0,3

1.425 456 126 825 18 791 268 5 502 16 634 188 121 323 2

46,5 0,2

47,8 1,1

2.850 63 0 2.773 14

13.114 456 11.815 825 18 1.084 268 298 502 16 12.030 188 11.517 323 2

LATVIA 2.270.894 NO DATA

134 0 0 134 0

15,1

15,1

0 40

40

0 11

11

51 0 0 51

24,7

24,7

0 83

83

0

0

0

0

0 0 0 0

105

105

LITHUANIA 3.366.357 2008

LUXEMBOURG 483.799 NO DATA

MALTA 410.584 NO DATA

NETHERLANDS 16.404.282 NO DATA

283 106 174 3 0

7,4 2,8 4,6 0,1

133 37 94 2

283 106 174 3 0 150 69 80 1

1 35

36

186 69 80 2 35 150 69 80 1

POLAND 38.115.641 2008

10:01

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

7

7

ITALY 59.578.359 2008

24/7/09

N° of transplants - Autologous

N° of donations - Unrelated

N° of donations - Related

N° of donations - Allogenic

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

TYPE OF HPC CELLS

IRELAND 4.419.859 NO DATA

EUROPEAN UNION COUNTRIES HUNGARY 10.045.000 NO DATA

N° of donations - Autologous

GREECE 11.214.992 2008

TYPE OF DATA

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON HPC CELLS

NEWSLETTER TRANSPLANT 14-09:aula medica Página 46

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

379 28 8 343 0

11,3 2,4 0,7 8,3

40 7 3 30

80 18 4 58

120 25 7 88

24,4 0,3 0,1 24,0

259 3 1 255

116 0 0 116 0

1,1

1,1

0 0 0 0

24 0 0 24

24 0 0 24

2.116 146 138 1.832 0

17,4 2,9 3,0 11,5

314 59 135 120

474 72 3 399

788 131 138 519

29,0

4,3

1.313

1.328 15

314 59 135 120

474 72 3 399

788 131 138 519

1.313

1.328 15

SPAIN 45.283.259 2008

29,3 0,3

SLOVENIA 2.025.866 NO DATA

4,3

92 0 0 92

481

481

19

19

500 0 500 0

SLOVAKIA 5.400.998 2008

EUROPEAN UNION COUNTRIES SWEDEN 9.182.927 NO DATA

3.755 502 133 3.120 0

24,3 4,3 2,2 17,9

846 123 126 597

644 139 7 498

1.490 262 133 1.095

33,1

37,0 3,9

2.265 240 0 2.025

4.819 259 3.440 1.120

908 143 93 672

5.727 402 3.533 1.792

8.997 410 4.549 4.038

157 18 0 139 0

2,0

6,1 4,1

0

1 1

9

26 17

27 18 0 9

29,3

29,3

130

130 0

0

2 2

8

21 13

23 15 0 8

128

129 1

ICELAND 314.321 NO DATA

MACEDONIA 2.045.179 NO DATA

OTHER COUNTRIES UNITED KINGDOM CROATIA 61.270.283 4.435.383 2008 2008

Total N. of transplants

PMP transplants - Allogenic

N° of transplants - Unrelated

N° of transplants - Related

N° of transplants - Allogenic

PMP transplants - Autologous

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

0 0 0 0

37 0 0 37

37 0 0 37

143 0 0 143

ROMANIA 21.528.627 2008

10:01

N° of transplants - Autologous

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

TYPE OF HPC CELLS

PORTUGAL 10.617.575 2008

24/7/09

N° of donations - Unrelated

N° of donations - Related

N° of donations - Allogenic

N° of donations - Autologous

TYPE OF DATA

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON HPC CELLS

NEWSLETTER TRANSPLANT 14-09:aula medica Página 47

47

48

Total N. of transplants

PMP transplants - Allogenic

N° of transplants - Unrelated

N° of transplants - Related

N° of transplants - Allogenic

PMP transplants - Autologous

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

994 94 8 892 0

5,9 1,2 0,1 4,6

12 2 1 9

406 83 7 316

418 85 8 325

8,0

8,2 0,1

576 9 0 567

12 2 1 9

406 83 7 316

418 85 8 325

592

41

142

409

22

0

8

14

CUBA 11.236.790 2008

184 72 93 19 0

MEXICO 106.680.000 2008

8

8

PANAMA 3.300.000 2008

LATINAMERICAN COUNTRIES

96

2

15

79

URUGUAY 3.323.906 2008

77

6

16

55

VENEZUELA 27.930.000 2008

10:01

N° of transplants - Autologous

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

554 9 0 545

ARGENTINA 39.745.593 2008

24/7/09

N° of donations - Unrelated

N° of donations - Related

N° of donations - Allogenic

BONE MARROW CORD BOOLD PERIPHERAL BLOOD PERIPHERAL BLOOD & BONE MARROW

TYPE OF HPC CELLS

TURKEY 70.586.256 2008

N° of donations - Autologous

SWITZERLAND 7.591.414 NO DATA

OTHER COUNTRIES NORWAY 4.737.171 NO DATA

TYPE OF DATA

Country Population (Font: eurostat 1.1.2008) Data related to year

PRELIMINARY DATA ON HPC CELLS

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COUNCIL OF EUROPE

CONSEIL DE L’EUROPE

“The Declaration of Istanbul on Organ Trafficking and Transplant Tourism”.

Year 2008

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THE DECLARATION OF ISTANBUL on Organ Trafficking and Transplant Tourism Participants in the International Summit on Transplant Tourism and Organ Trafficking convened by The Transplantation Society and International Society of Nephrology in Istanbul, Turkey, April 30–May 2, 2008*

PREAMBLE Organ transplantation, one of the medical miracles of the twentieth century, has prolonged and improved the lives of hundreds of thousands of patients worldwide. The many great scientific and clinical advances of dedicated health professionals, as well as countless acts of generosity by organ donors and their families, have made transplantation not only a life-saving therapy but a shining symbol of human solidarity. Yet these accomplishments have been tarnished by numerous reports of trafficking in human beings who are used as sources of organs and of patienttourists from rich countries who travel abroad to purchase organs from poor people. In 2004, the World Health Organization, called on member states “to take measures to protect the poorest and vulnerable groups from transplant tourism and the sale of tissues and organs, including attention to the wider problem of international trafficking in human tissues and organs” (1).

To address the urgent and growing problems of organ sales, transplant tourism and trafficking in organ donors in the context of the global shortage of organs, a Summit Meeting of more than 150 representatives of scientific and medical bodies from around the world, government officials, social scientists, and ethicists, was held in Istanbul from April 30 to May 2, 2008. Preparatory work for the meeting was undertaken by a Steering Committee convened by The Transplantation Society (TTS) and the International Society of Nephrology (ISN) in Dubai in December 2007. That committee’s draft declaration was widely circulated and then revised in light of the comments received. At the Summit, the revised draft was reviewed by working groups and finalized in plenary deliberations.

This Declaration represents the consensus of the Summit participants. All countries need a legal and 50

professional framework to govern organ donation and transplantation activities, as well as a transparent regulatory oversight system that ensures donor and recipient safety and the enforcement of standards and prohibitions on unethical practices.

Unethical practices are, in part, an undesirable consequence of the global shortage of organs for transplantation. Thus, each country should strive both to ensure that programs to prevent organ failure are implemented and to provide organs to meet the transplant needs of its residents from donors within its own population or through regional cooperation. The therapeutic potential of deceased organ donation should be maximized not only for kidneys but also for other organs, appropriate to the transplantation needs of each country. Efforts to initiate or enhance deceased donor transplantation are essential to minimize the burden on living donors. Educational programs are useful in addressing the barriers, misconceptions and mistrust that currently impede the development of sufficient deceased donor transplantation; successful transplant programs also depend on the existence of the relevant health system infrastructure.

Access to healthcare is a human right but often not a reality. The provision of care for living donors before, during and after surgery–as described in the reports of the international forums organized

by TTS in Amsterdam and Vancouver (2-4)–is no less essential than taking care of the transplant recipient. A positive outcome for a recipient can never justify harm to a live donor; on the contrary, for a transplant with a live donor to be regarded as a success means that both the recipient and the donor have done well.

This Declaration builds on the principles of the Universal Declaration of Human Rights (5). The

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broad representation at the Istanbul Summit reflects the importance of international collaboration and global consensus to improve donation and transplantation practices. The Declaration will be submitted to relevant professional organizations and to the health authorities of all countries for consideration. The legacy of transplantation must not be the impoverished victims of organ trafficking and transplant tourism but rather a celebration of the gift of health by one individual to another.

DEFINITIONS Organ trafficking is the recruitment, transport, transfer, harboring or receipt of living or deceased persons or their organs by means of the threat or use of force or other forms of coercion, of abduction, of fraud, of deception, of the abuse of power or of a position of vulnerability, or of the giving to, or the receiving by, a third party of payments or benefits to achieve the transfer of control over the potential donor, for the purpose of exploitation by the removal of organs for transplantation (6).

Transplant commercialism is a policy or practice in which an organ is treated as a commodity, including by being bought or sold or used for material gain.

Travel for transplantation is the movement of organs, donors, recipients or transplant professionals across jurisdictional borders for transplantation purposes. Travel for transplantation becomes transplant tourism if it involves organ trafficking and/or transplant commercialism or if the resources (organs, professionals and transplant centers) devoted to providing transplants to patients from outside a country undermine the countryâ&#x20AC;&#x2122;s ability to provide transplant services for its own population.

with end-stage diseases, such as dialysis programs for renal patients, to minimize morbidity and mortality, alongside transplant programs for such diseases; c. Organ transplantation as the preferred treatment for organ failure for medically suitable recipients.

2. Legislation should be developed and implemented by each country or jurisdiction to govern the recovery of organs from deceased and living donors and the practice of transplantation, consistent with international standards: a. Policies and procedures should be developed and implemented to maximize the number of organs available for transplantation, consistent with these principles; b. The practice of donation and transplantation requires oversight and accountability by health authorities in each country to ensure transparency and safety; c. Oversight requires a national or regional registry to record deceased and living donor transplants; d. Key components of effective programs include public education and awareness, health professional education and training, and defined responsibilities and accountabilities for all stakeholders in the national organ donation and transplant system.

3. Organs for transplantation should be equitably allocated within countries or jurisdictions to suitable recipients without regard to gender, ethnicity, religion, or social or financial status:

PRINCIPLES 1. National governments, working in collaboration with international and non-governmental organizations, should develop and implement comprehensive programs for the screening, prevention and treatment of organ failure, which include: a. The advancement of clinical and basic science research; b. Effective programs, based on international guidelines, to treat and maintain patients

a. Financial considerations or material gain of any party must not influence the application of relevant allocation rules.

4. The primary objective of transplant policies and programs should be optimal short- and longterm medical care to promote the health of both donors and recipients: a. Financial considerations or material gain of any party must not override primary consideration for the health and well-being of donors and recipients.

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5. Jurisdictions, countries and regions should strive to achieve self-sufficiency in organ donation by providing a sufficient number of organs for residents in need from within the country or through regional cooperation: a. Collaboration between countries is not inconsistent with national self-sufficiency as long as the collaboration protects the vulnerable, promotes equality between donor and recipient populations, and does not violate these principles; b. Treatment of patients from outside the country or jurisdiction is only acceptable if it does not undermine a country’s ability to provide transplant services for its own population.

6. Organ trafficking and transplant tourism violate the principles of equity, justice and respect for human dignity and should be prohibited.

Because transplant commercialism targets impoverished and otherwise vulnerable donors, it leads inexorably to inequity and injustice and should be prohibited. In Resolution 44.25, the World Health Assembly called on countries to prevent the purchase and sale of human organs for transplantation: a. Prohibitions on these practices should include a ban on all types of advertising (including electronic and print media), soliciting, or brokering for the purpose of transplant commercialism, organ trafficking, or transplant tourism. b. Such prohibitions should also include penalties for acts —such as medically screening donors or organs, or transplanting organs— that aid, encourage, or use the products of, organ trafficking or transplant tourism. c. Practices that induce vulnerable individuals or groups (suchas illiterate and impoverished persons, undocumented immigrants, prisoners, and political or economic refugees) to become living donors are incompatible with the aim of combating organ trafficking, transplant tourism and transplant commercialism.

increase the donor pool and to prevent organ trafficking, transplant commercialism and transplant tourism and to encourage legitimate, life-saving transplantation programs: To respond to the need to increase deceased donation: 1. Governments, in collaboration with health care institutions, professionals, and nongovernmental organizations should take appropriate actions to increase deceased organ donation. Measures should be taken to remove obstacles and disincentives to deceased organ donation.

2. In countries without established deceased organ donation or transplantation, national legislation should be enacted that would initiate deceased organ donation and create transplantation infrastructure, so as to fulfill each country’s deceased donor potential.

3. In all countries in which deceased organ donation has been initiated, the therapeutic potential of deceased organ donation and transplantation should be maximized.

4. Countries with well established deceased donor transplant programs are encouraged to share information, expertise and technology with countries seeking to improve their organ donation efforts.

To ensure the protection and safety of living donors and appropriate recognition for their heroic act while combating transplant tourism, organ trafficking and transplant commercialism: 1. The act of donation should be regarded as heroic and honored as such by representatives of the government and civil society organizations.

2. The determination of the medical and psychosocial suitability of the living donor should be guided by the recommendations of the Amsterdam and Vancouver Forums (2-4): a. Mechanisms for informed consent should incorporate provisions for evaluating the donor’s understanding, including assessment of the psychological impact of the process;

PROPOSALS Consistent with these principles, participants in the Istanbul Summit suggest the following strategies to 52

b. All donors should undergo psychosocial evaluation by mental health professionals during screening.

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3. The care of organ donors, including those who have been victims of organ trafficking, transplant commercialism, and transplant tourism, is a critical responsibility of all jurisdictions that sanctioned organ transplants utilizing such practices.

4. Systems and structures should ensure standardization, transparency and accountability of support for donation: a. Mechanisms for transparency of process and follow-up should be established; b. Informed consent should be obtained both for donation and for follow-up processes.

5. Provision of care includes medical and psychosocial care at the time of donation and for any short- and long-term consequences related to organ donation: a. In jurisdictions and countries that lack universal health insurance, the provision of disability, life, and health insurance related to the donation event is a necessary requirement in providing care for the donor; b. In those jurisdictions that have universal health insurance, governmental services should ensure donors have access to appropriate medical care related to the donation event; c. Health and/or life insurance coverage and employment opportunities of persons who donate organs should not be compromised; d. All donors should be offered psychosocial services as a standard component of follow-up; e. In the event of organ failure in the donor, the donor should receive: i. Supportive medical care, including dialysis for those with renal failure, and ii. Priority for access to transplantation, integrated into existing allocation rules as they apply to either living or deceased organ transplantation.

6. Comprehensive reimbursement of the actual, documented costs of donating an organ does not constitute a payment for an organ, but is rather part of the legitimate costs of treating the recipient:

a. Such cost-reimbursement would usually be made by the party responsible for the costs of treating the transplant recipient (such as a government health department or a health insurer); b. Relevant costs and expenses should be calculated and administered using transparent methodology, consistent with national norms; c. Reimbursement of approved costs should be made directly to the party supplying the service (such as to the hospital that provided the donorâ&#x20AC;&#x2122;s medical care); d. Reimbursement of the donorâ&#x20AC;&#x2122;s lost income and out-of-pockets expenses should be administered by the agency handling the transplant rather than paid directly from the recipient to the donor.

7. Legitimate expenses that may be reimbursed when documented include: a. the cost of any medical and psychological evaluations of potential living donors who are excluded from donation (e.g., because of medical or immunologic issues discovered during the evaluation process); b. costs incurred in arranging and effecting the pre-, peri- and post-operative phases of the donation process (e.g., long-distance telephone calls, travel, accommodation and subsistence expenses); c. medical expenses incurred for postdischarge care of the donor; d. lost income in relation to donation (consistent with national norms).

REFERENCES 1. World Health Assembly Resolution 57.18, Human organ and tissue transplantation, 22 May 2004, http://www.who.int/gb/ebwha/ pdf_files/WHA57/A57_R18-en.pdf.

2. The Ethics Committee of the Transplantation Society (2004). The Consensus Statement of the Amsterdam Forum on the Care of the Live Kidney Donor. Transplantation 78(4):491-92.

3. Barr ML, Belghiti J, Villamil FG, Pomfret EA, Sutherland DS, Gruessner RW, Langnas AN & 53

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Delmonico FL (2006). A Report of the Vancouver Forum on the Care of the Life Organ Donor: Lung, Liver, Pancreas, and Intenstine Data and Medical Guidelines. Transplantation 81(10):1373-85.

4. Pruett TL, Tibell A, Alabdulkareem A, Bhandari M, Cronon DC, Dew MA, Dib-Kuri A, Gutmann T, Matas A, McMurdo L, Rahmel A, Rizvi SAH, Wright L & Delmonico FL (2006). The Ethics Statement of the Vancouver Forum on the Live Lung, Liver, Pancreas, and Intestine Donor.

Transplantation 81(10):1386-87.

5. Universal Declaration of Human Rights, adopted by the UN General Assembly on December 10, 1948, http://www.un.org/ Overview/rights.html.

6. Based on Article 3a of the Protocol to Prevent, Suppress and Punish Trafficking in Persons, Especially Women and Children, Supplementing the United Nations Convention Against Transnational Organized Crime, http://www.uncjin.org/Documents/Conventions/ dcatoc/final_ documents_2/convention_ %20traff_eng.pdf.

The Participants in the International Summit on Transplant Tourism and Organ Trafficking and the manner in which they were chosen and the meeting was organized were as follows: PROCESS AND PARTICIPANT SELECTION

• Individuals holding leadership positions in nephrology and transplantation;

Steering Committee: The Steering Committee was selected by an Organizing Committee consisting of Mona Alrukhami, Jeremy Chapman, Francis Delmonico, Mohamed Sayegh, Faissal Shaheen, and Annika Tibell.

The Steering Committee was composed of leadership from The Transplantation Society, including its President-elect and the Chair of its Ethics Committee, and the International Society of Nephrology, including its Vice President and individuals holding Council positions. The Steering Committee had representation from each of the continental regions of the globe with transplantation programs.

54

• Stakeholders in the public policy aspect of organ transplantation; and • Ethicists, anthropologists, sociologists, and legal scholars well-recognized for their writings regarding transplantation policy and practice.

No person or group was polled with respect to their opinion, practice, or philosophy prior to the Steering Committee selection or the Istanbul Summit.

After the proposed group of participants was prepared and reviewed by the Steering Committee, they were sent an letter of invitation to the Istanbul Summit, which included the following components:

The mission of the Steering Committee was to draft a Declaration for consideration by a diverse group of participants at the Istanbul Summit. The Steering Committee also had the responsibility to develop the list of participants to be invited to the Summit meeting.

• the mission of the Steering Committee to draft a Declaration for all Istanbul participants’ consideration;

Istanbul Participant Selection:

• the procedure for the selection of participants;

Participants at the Istanbul Summit were selected by the Steering Committee according to the following considerations:

• the work group topics;

• the agenda and work group format of the Summit;

• an invitation to the participants to indicate their work group preferences;

• The country liaisons of The Transplantation Society representing virtually all countries with transplantation programs;

• the intent to communicate a draft and other materials before the Summit convened;

• Representatives from international societies and the Vatican;

• the Summit goals to assemble a final Declaration that could achieve consensus and

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would address the issues of organ trafficking, transplant tourism and commercialism, and provide principles of practice and recommended alternatives to address the shortage of organs; • an acknowledgment of the funding provided by Astellas Pharmaceuticals for the Summit; • provision of hotel accommodations and travel for all invited participants.

Of approximately 170 persons invited, 160 agreed to participate and 152 were able to attend the Summit in Istanbul on April 30-May 2, 2008.

Because work on the Declaration at the Summit was to be carried out by dividing the draft document into separate parts, Summit invitees were assigned to a work group topic based on their response concerning the particular topics on which they wished to focus their attention before and during the Summit.

Preparation of the Declaration: The draft Declaration prepared by the Steering Committee was furnished to all participants with ample time for appraisal and response prior to the Summit. The comments and suggestions received in advance were reviewed by the Steering

Committee and given to leaders of the appropriate work group at the Summit. (Work group leaders were selected and assigned from the Steering Committee.)

The Summit meeting was formatted so that breakout sessions of the work groups could consider the written responses received from participants prior to the Summit as well as comments from each of the work group participants. The work groups elaborated these ideas as proposed additions to and revisions of the draft. When the Summit reconvened in plenary session, the Chairs of each work group presented the outcome of their breakout session to all Summit participants for discussion. During this process of review, the wording of each section of the Declaration was displayed on a screen before the plenary participants and was modified in light of their comments until consensus was reached on each point.

The content of the Declaration is derived from the consensus that was reached by the participants at the Summit in the plenary sessions which took place on May 1 and 2, 2008. A formatting group was assembled immediately after the Summit to address punctuation, grammatical and related concerns and to record the Declaration in its finished form.

PARTICIPANTS IN THE ISTANBUL SUMMIT Last Name Abboud *Abbud-Filho Abdramanov Abdulla Abraham Abueva Aderibigbe *Al-Mousawi Alberu Allen Almazán-Gómez Alnono *Alobaidli *Alrukhaimi Álvarez Assad Assounga Baez *Bagheri *Bakr Bamgboye *Barbari

First Name Omar Mario Kaldarbek Sadiq Georgi Amihan V. Ademola Mustafa Josefina Richard D.M. Lynn C. Ibrahim Ali Abdulkareem Mona Inés Lina Alain G. Yenny Alireza Mohamed Adel Ebun Antoine

Country Sudan Brazil Kyrgyzstan Bahrain India Philippines Nigeria Kuwait Mexico Australia Philippines Yemen United Arab Emirates United Arab Emirates Uruguay Saudi Arabia South Africa Colombia Iran Egypt Nigeria Lebanon

Last Name Belghiti Ben Abdallah Ben Ammar Bos Britz Budiani *Capron Castro *Chapman Chen Codreanu Cole Cozzi *Danovitch Davids De Broe *De Castro *Delmonico Derani Dittmer Domínguez-Gil Duro-García

First Name Jacques Taieb Mohamed Salah Michael Russell Debra Alexander Cristina R. Jeremy Zhonghua Klaus Igor Edward Emanuele Gabriel Razeen Marc Leonardo Francis L. Rania Ian Beatriz Valter

Country France Tunisia Tunisia The Netherlands South Africa USA USA Brazil Australia People’s Republic of China Moldova Canada Italy USA South Africa Belgium Philippines USA Syria New Zealand Spain Brazil 55

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Last Name First Name Ehtuish Ehtuish El-Shoubaki Hatem Epstein Miran *Fazel Iraj Fernández Zincke Eduardo García-Gallont Rudolf Ghods Ahad J. Gill John Glotz Denis Gopalakrishnan Ganesh Gracida Carmen Grinyo Josep Ha Jongwon *Haberal Mehmet A. Hakim Nadey Harmon William Hasegawa Tomonori Hassan Ahmed Adel Hickey David Hiesse Christian Hongji Yang Humar Inés Hurtado Abdias Ismail Moustafa Wesam Ivanovski Ninoslav *Jha Vivekanand Kahn Delawir Kamel Refaat Kirpalani Ashok Kirste Guenter *Kobayashi Eiji Koller Jan Kranenburg Leonieke *Lameire Norbert Laouabdia-Sellami Karim Lei Ruipeng *Levin Adeera Lloveras Josep Lõhmus Aleksander Luciolli Esmeralda Lundin Susanne Lye Wai Choong Lynch Stephen *Maïga Mahamane Mamzer Bruneel Marie-France Maric Nicole *Martin Dominique *Masri Marwan Matamoros Maria A. Matas Arthur McNeil Adrian Meiser Bruno Meši Enisa Moazam Farhat

Country Libya Qatar United Kingdom Iran Belgium Guatemala Iran Canada France India Mexico Spain South Korea Turkey United Kingdom USA Japan Egypt Ireland France People’s Republic of China Croatia Peru Egypt Macedonia India South Africa Egypt India Germany Japan Slovakia The Netherlands Belgium France People’s Republic of China Canada Spain Estonia France Sweden Singapore Australia Mali France Austria Australia Lebanon Costa Rica USA United Kingdom Germany Bosnia Pakistan

Last Name Mohsin Mor Morales Munn Murphy *Naicker Naqvi *Noël Obrador Oliveros Ona Oosterlee Oyen Padilla Pratschke Rahamimov Rahmel Reznik *Rizvi Roberts *Rodriguez-Iturbe Rowinski Saeed Sarkissian *Sayegh Scheper-Hughes Sever *Shaheen Sharma Shinozaki Simforoosh Singh Sok Hean Somerville Stadtler *Stephan Suárez Suaudeau Sumethkul Takahara Thiel *Tibell Tomadze *Tong Tsai Uriarte Vanrenterghem *Vathsala Weimar Wikler Young Yuldashev Zhao

First Name Nabil Eytan Jorge Stephen Mark Saraladevi S.A. Anwar Luc Gregorio Yolanda Enrique Arie Ole Benita Johann Ruth Axel Oleg S. Adibul Hasan Lesley Ann Bernardo Wojciech Bassam Ashot Mohamed H. Nancy Mehmet Sukru Faissal A. Dhananjaya Naoshi Nasser Harjit Thong Margaret Maria Antoine Juliette Msgr. Jacques Vasant Shiro Gilbert T. Annika Gia Matthew Kwok-Lung Daniel Fu-Chang Remedios Yves F.C. A. Willem Daniel Kimberly Ulugbek Minggang

Country Oman Israel Chile New Zealand Ireland South Africa Pakistan WHO Mexico Philippines Philippines The Netherlands Norway Philippines Germany Israel The Netherlands Russia Pakistan Trinidad and Tobago Venezuela Poland Syria Armenia USA USA Turkey Saudi Arabia India Japan Iran Malaysia Cambodia Canada USA Lebanon Cuba Italy Thailand Japan Switzerland Sweden Georgia Hong Kong Taiwan Philippines Belgium Singapore The Netherlands USA Canada Uzbekistan People’s Republic of China

* = Members of the Steering Committee. (William Couser, USA, was also a member of the Steering Committee but was unable to attend the Summit.)

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LIST OF PARTICIPANTS CD-P-TO (16-17/10/08, Strasbourg) AUSTRIA Dr. MUEHLBACHER Ferdinand BELGIUM Dr. COENE Leen BULGARIA Dr. BRANKOV Dimitar CYPRUS CZECH REPUBLIC Dr. BREZOVSKY Pavel DENMARK ESTONIA Dr. DMITRIEV Peeter FINLAND Dr. SALMELA Kaija FRANCE Dr. LAOUABDIA-SELLAMI Karim GERMANY Dr. KIRSTE Günter GREECE Dr. GOMBOU Athina HUNGARY Dr. PERNER Ferenc IRELAND ITALY Dr. NANNI COSTA Alessandro Dr. RAGO Claudio LATVIA LITHUANIA LUXEMBOURG Dr. MOUSTY Raymond MALTA NETHERLANDS Dr. HAASE-KROMWIJK Bernadette POLAND Dr. ROWINSKI Wojciech POTUGAL Dr. FRANCA Ana REPUBLIC OF MOLDOVA Dr. CODREANU Igor ROMANIA Dr. ZOTA Victor SLOVENIA Dr. AVSEC- LETONJA Danica SPAIN Dr. MATESANZ Rafael Dr. DOMINGUEZ-GIL Beatriz SLOVAK REPUBLIC SWEDEN Dr. ERICZON Bo-Göran UNITED KINGDOM

(ET) EUROTRANSPLANT Austria, Belgium, Croatia, Germany, Luxemburg, Netherlands, Slovenia Dr. OOSTERLEE Arie Dr. RAHMEL Axel (SKT) SCANDIATRANSPLANT Denmark, Finland, Norway, Sweden, Iceland Dr. JAKOBSEN Arnt

ARMENIA BELARUS BOSNIA AND HERZEGOVINA CANADA Dr. AGBANYO Francisca CROATIA Dr. KOCMAN Branislav GEORGIA ICELAND ISRAEL Dr. ASHKENAZI Tamar NORWAY Dr. PFEFFER Per RUSSIAN FEDERATION SERBIA SWITZERLAND Dr. MOREL Philippe TURKEY

UNOS Dr. PRUETT Timothy IBEROAMERICAN COUNCIL Dr. MORALES BELLINI Fernando CDBI GARANI-PAPADATOS Stamatia Dr. DE SOLA LLERA Carlos Dr. GORSETH Hallvard Dr. LWOFF Laurence Dr. REQUENA Marta Dr. SPIESER Jean-Marc (Head of DBO) M-E. BEHR-GROSS (Secretariat) EUROPEAN COMMISSION Dr. FERNANDEZ-ZINCKE Eduardo WHO

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NEWSLETTER TRANSPLANT 14-09:aula medica

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