ORAL HEALTH AMERICA
Repaving Tobacco Road: Emerging Tobacco Products and their Implications for Oral Health
August 26, 2014
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Repaving Tobacco Road: Emerging Tobacco Products and their Implications for Oral Health Scott L. Tomar, DMD, DrPH University of Florida stomar@dental.ufl.edu Sharee Clough, RDH, MS Ed American Dental Association cloughs@ada.org
Outline •New and emerging tobacco products •“Harm reduction” and new products •Big Tobacco and new products •Implications for oral health and overall health
© 2014 American Dental Association, All Rights Reserved
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Smokeless Tobacco
Š 2014 American Dental Association, All Rights Reserved
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SNUS
Š 2014 American Dental Association, All Rights Reserved
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Cigarette, Cigar, Cigarillo, or Little Cigar?
Š 2014 American Dental Association, All Rights Reserved
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Š 2014 American Dental Association, All Rights Reserved
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Sweet Cigarillos
Š 2014 American Dental Association, All Rights Reserved
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Bidis and Kreteks
Bidis
Kreteks
Š 2014 American Dental Association, All Rights Reserved
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Electronic Cigarettes
Š 2014 American Dental Association, All Rights Reserved
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Hookahs
http://http://www.captain-hookah.com/?page_id=2 Š 2014 American Dental Association, All Rights Reserved
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Dissolvables
Adverse Health Effects of ST Use • • • • • • • • •
Oral and pharyngeal cancer Pancreatic cancer Smokeless tobacco keratosis / leukoplakia Gingival recession Dental caries (chewing tobacco) Cardiovascular diseases Type 2 diabetes and insulin resistance (?) Reproductive health effects Nicotine addiction © 2014 American Dental Association, All Rights Reserved
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“Traditional” Types of Smokeless Tobacco
Smokeless Tobacco Lesions
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Percent
Prevalence of ST Lesions Among Snuff Users Age 12-17 Years, by Duration of Use 45 40 35 30 25 20 15 10 5 0
38.3
22.9
8.4 1.9 <1 mo.
1-12 mo.
13-24 mo.
Duration of Use Source: Tomar et al. J Dent Res 1997; 76:1277-86.
>24 mo.
Gingival Recession
Recent Developments in U.S. Smokeless Tobacco (ST) Industry Until 2006, most ST in the U.S. made by companies that did not sell cigarettes 2006: Reynolds American acquires Conwood Co. 2008: Altria acquires US Smokeless Tobacco Co. 2008: Lorillard joint venture with Swedish Match 2008: Liggett introduces Grand Prix Snus 2009: PMI joint venture with Swedish Match 2010: Nearly entire U.S. ST industry controlled by cigarette companies
© 2014 American Dental Association, All Rights Reserved
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Š 2014 American Dental Association, All Rights Reserved
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US Airways Magazine. November 2011
Images courtesy of Trinketsandtrash.com
Connolly et al. Pediatrics 2010;125:896-9.
13,705 cases of accidental poisoning from ingestion of tobacco products by children <6 yrs old, 2006-2008 >70% by infants <1 At least 1 case of poisoning by ingestion of Orbs by 3yr-old Orbs contain 1 mg nicotine, pH 7.8 Estimated lethal dose: 1.0 mg nicotine/kg body weight 16-27 Orbs probably fatal dose for 4-year-old
© 2014 American Dental Association, All Rights Reserved
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Tobacco Industry Strategies • Promote dual use of ST and cigarettes
• Undermine effectiveness of smokefree ordinances in reducing smoking • Diversified products under prospect of federal regulation • Continue aggressive promotion to young people Carpenter et al. Developing smokeless tobacco products for smokers: an examination of tobacco industry documents. Tob Control 2009;18(1):54-9. © 2014 American Dental Association, All Rights Reserved
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Sales of Smokeless Tobacco United States, 1986-2011
Billions of Dollars
$3.0 $2.5 $2.0
Moist snuff
$1.5
Scotch/Dry Snuff
$1.0
Loose Leaf Chewing Tobacco
$0.5
Snus
$0.0 1986 1990 1994 1998 2002 2006 2010
Federal Trade Commission Report to Congress, 2013 Š 2014 American Dental Association, All Rights Reserved
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Current Use of Cigarettes or ST among Male High School Seniors US Monitoring the Future Project, 1992-2013
40 35
Cigarettes
Percent
30 25 20
Smokeless Tobacco
15 10 5 0 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 Year Johnston, Oâ&#x20AC;&#x2122;Malley, Bachman, & Schulenberg (2013)
ST and Tobacco Harm Reduction: The Theory • Exclusive use of ST products carries lower risk for death and disease than smoking
• Smokers unable or unwilling to quit could reduce risks by switching to ST • The decline in smoking by Swedish men was largely due to switch to snus
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The “Swedish Experience”
Foulds et al. Tobacco Control 2003;12(4):349-59. © 2014 American Dental Association, All Rights Reserved
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ST and Tobacco Harm Reduction: The Reality • Little evidence for snus as effective smoking cessation strategy
• Smoking in Sweden declined among women despite very low use of snus • Smoking now lower for women than men <35 • Harm associated with product is function of how it is used, not just its composition
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Concerns about Cigarette Company Control of ST Market
• Promote dual use/situational substitute • Deferred smoking cessation • Dual use and dual addiction • Increased ST initiation by young people • Potential for either reduction or increase of public health harm
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Prevalence of Current Smoking among Daily ST Users 80
Percent Who Smoke
70 60 50 Less than daily smoking Daily smoking
40 30 20 10 0 Middle school High school
Adults
Tomar, Alpert, Connolly. Tobacco Control 2010; 19:104-9. Š 2014 American Dental Association, All Rights Reserved
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Prevalence of Current Smoking among NonDaily ST Users 70
Percent Who Smoke
60 50 40
Less than daily smoking Daily smoking
30 20 10 0 Middle school High school
Adults
Tomar, Alpert, Connolly. Tobacco Control 2010; 19:104-9. Š 2014 American Dental Association, All Rights Reserved
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Seriously Considering Quitting Smoking Within Next 6 Months, Male Daily Smokers, by Snuff Use Status
Percent Considering Quitting
60 48.0
50 40
44.8 39.2
36.5
30 20 10 0 Daily Snuff User
Some day Snuff User
Tomar, Alpert, Connolly. Tobacco Control
Former Snuff User 2010; 19:104-9.
Never Used Snuff
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Quit Smoking for 1+ Days in Past 12 Months, Male Daily Smokers, by Snuff Use Status
Percent Who Tried to Quit Smoking
45
41.2
40 35 30
31.1 27.9
29.6
25
20 15 10 5 0 Daily Snuff User
Some day Snuff User
Former Snuff User
Never Used Snuff
Tomar, Alpert, Connolly. Tobacco Control 2010; 19:104-9. Š 2014 American Dental Association, All Rights Reserved
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Electronic Cigarettes (E-cigarettes)
Vaporized nicotine At least 25 different manufacturers Little data on constituents of vapor No data on efficacy for smoking cessation Controversy over use in smoke-free areas Feb 2010, US District Court ruled FDA lacked authority to regulate e-cigs as drug-delivery device Regulated by FDA as tobacco product © 2014 American Dental Association, All Rights Reserved
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E-Cigarettes • FDA testing of several brands found: – – – –
Diethylene glycol Tobacco-specific nitrosamines Tobacco-specific impurities Inconsistent nicotine dosing
• Recent report of lipoid pneumonia in e-cig smoker*
http://www.fda.gov/downloads/Drugs/ScienceResearch/UCM173250.pdf *McCauley et al. Chest 2012;141(4):1110-3 © 2014 American Dental Association, All Rights Reserved
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Big Tobacco enters the e-cigarette market • Altria Group (Marlboro): MarkTen launched nationally Q2 2014 • Lorillard (Newport): acquired Blu in 2012; SKYCIG in 2013 • Reynolds American (Camel): launched VUSE June 2013
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E-Cigs Projected to be $3 Billion Market by 2015
http://www.businessinsider.com/e-cigarettes-will-be-3-billion-market-2013-5 Š 2014 American Dental Association, All Rights Reserved
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E-Cigarette Ever Use Among US Middle and High School Students
CDC. MMWR 2013; 62(35):729-30 http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6235a6.htm Š 2014 American Dental Association, All Rights Reserved
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Hookah (Waterpipe)
Maziak W. Cancer Epidemiol 2013;37:1-4
Health Effects of Hookah Smoking • High levels of CO & toxins • Increased risk of: – Lung cancer – Respiratory illness – Low birth weight – Periodontitis – Post-extraction dry socket
• Probable increased risk for oral cancer • Possible transmission of infectious agents Akl et al. Int J Epidemiol 2010; 39: 834–57; Maziak W. Cancer Epidemiol 2013;37:1-4
Current Hookah Smoking by U.S. High School Students National Youth Tobacco Surveys 2011 & 2012 7
Percent Current Hookah Smoking
6.2 6 5 4 3
4.5
3.5
4.8
2011 2012
2 1 0
Boys CDC. MMWR 2013;62:893-7.Girls http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6245a2.htm?s_cid=%20mm6245a2.htm_w Š 2014 American Dental Association, All Rights Reserved
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Current Hookah Smoking by U.S. Undergraduate College Students, National College Health Assessments, 2009-2013 14
Percent Current Hookah Smoking
12.3 12
Males
10.1
10.1
10.3
10.5
10
8.8 7.3Females 7.2
8 6.2
6.2
2009
2010
6 4 2
0 2011
2012
2013
American College Health Association. http://www.acha-ncha.org/reports_ACHA-NCHAII.html Š 2014 American Dental Association, All Rights Reserved
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Summary • All forms of tobacco use have known or probable adverse effects on general health and oral health • Tobacco landscape is changing rapidly • New (and old) smokeless tobacco products and ecigarettes being heavily promoted
• Weak evidence base for non-cigarette tobacco products as effective method to quit smoking • Net harm to individual and population depends how product is used • Likely to be intense debate around product regulation © 2014 American Dental Association, All Rights Reserved
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