APRIL 16, 2025
Penn Dental Medicine 9:00am – 6:00pm
WELCOME 2025
It is our great pleasure to welcome alumni, faculty, staff, students, and friends to Penn Dental Medicine’s Research Day 2025.
We invite you to join us in celebrating the breadth and excellence of research at Penn Dental Medicine. This year, once again, our faculty, students, and research staff will come together to showcase the full spectrum of PDM’s research endeavors in a single venue. The program will feature two keynote speakers, faculty presentations, and more than 90 research posters. We look forward to a dynamic day of interdisciplinary exchange and collaboration that highlights the quality, depth, and diversity of the School’s research.
We are delighted to welcome our distinguished guest speakers, Dr. Sumita BhaduriMcIntosh and Dr. Michail Lionakis. Dr. Bhaduri-McIntosh, Professor of Pediatric Infectious Diseases in the Departments of Pediatrics and Molecular Genetics & Microbiology at the University of Florida, honors us as the PDM Research Day Keynote Lecturer. She will present “Epstein-Barr Virus and Oral Health – Mechanistic Connections.” Dr. Michail Lionakis, Senior Investigator and Acting Chief of the Laboratory of Host Immunity and Microbiome; Deputy Chief of the Laboratory of Clinical Immunology & Microbiology; and Chief of the Fungal Pathogenesis Section at the National Institute of Allergy & Infectious Diseases, NIH, will deliver the Joseph L. Rabinowitz Memorial Lecture, “AIRE Deficiency: A Treatable IFN-γ-opathy.” We are thrilled to have them with us and look forward to the insights they will share.
Another highlight of the day is the presentation of the 2025 Joseph and Josephine Rabinowitz Award for Excellence in Research. The Rabinowitz Award supports pilot research among Penn Dental Medicine faculty, with an emphasis on interdisciplinary or interdepartmental collaborations. Established in 1992 by the late Dr. Joseph Rabinowitz, a valued member of the School’s Biochemistry faculty for 29 years, and his wife, Josephine, the award aims to encourage independent research among faculty. We extend a warm welcome and our heartfelt thanks to the Rabinowitz family for joining us.
Research Day will again offer travel grants to attend the IADR/AADOCR/CADR General Session & Exhibition in San Diego, CA, from March 25-28, 2026. This initiative, sponsored by PDM, supports ongoing research and fosters leadership among students and research investigators at Penn Dental Medicine. Five DMD students will be selected to receive the 2026 AADOCR Travel Award.
Penn Dental Medicine continues to advance as a leader in generating new knowledge and training the next generation of oral health researchers. We hope today inspires new collaborations, fresh insights, and innovative discoveries. Enjoy the day!
RESEARCH DAY COMMITTEE
Dr. Dana T. Graves Co-chair
Dr. Esra Sahingur Co-chair
Dr. Joe Fiorellini
Dr. Michael Glick
Dr. George Hajishengallis
Elizabeth Ketterlinus
Dr. Chenshuang Li
Dr. Rob Ricciardi
Pamela Rice
Esra Sahingur, DDS, MS, PhD
Co-Chair, Research Day Committee
Associate Dean of Graduate Studies
Dana Graves, DDS, DMSc
Co-Chair, Research Day Committee
Vice Dean for Scholarship and Research and Student Research
9:00 AM POSTER PRESENTATIONS AND COMPETITIONS
Schattner Lobby, Lerner Pavilion, and Schattner Patient Waiting
11:00 AM Break
11:15 AM OPENING REMARKS – Arthur E. Corby Auditorium
11:30 AM PDM RESEARCH DAY KEYNOTE LECTURE – Arthur E. Corby Auditorium
MODERATOR: Anh D. Le, DDS, PhD
“Epstein-Barr Virus and Oral Health – Mechanistic Connections”
Sumita Bhaduri-McIntosh, MD, PhD, Professor, Pediatric Infectious Diseases, Depts. of Pediatrics & Molecular Genetics and Microbiology, Director, Pediatric Infectious Disease Research, Children’s Miracle Network Scholar, UF Health Cancer Center, University of Florida
12:30 PM Lunch – Fonseca Gardens
1:30 PM PDM FACULTY PRESENTATION 1 – Arthur E. Corby Auditorium
MODERATOR: Kyle Vining, DDS, PhD
“The Dark Side of Trained Immunity”
George Hajishengallis, DDS, PhD, Thomas W. Evans Centennial Professor
2:00 PM THE JOSEPH L. RABINOWITZ MEMORIAL LECTURE – Arthur E. Corby Auditorium
MODERATOR: Esra Sahingur, DDS, MS, PhD
“AIRE Deficiency: A Treatable IFN-γ-opathy”
Michail Lionakis, MD, ScD, Senior Investigator Acting Chief, Laboratory of Host Immunity and Microbiome (LHIM) Deputy Chief, Laboratory of Clinical Immunology & Microbiology (LCIM) Chief, Fungal Pathogenesis Section, LCIM National Institute of Allergy & Infectious Diseases (NIAID), NIH, Laboratory of Host Immunity and Microbiome (LHIM), National Institute of Allergy & Infectious Diseases (NIAID), NIH
3:00 PM PDM FACULTY DIALOGUE – Arthur E. Corby Auditorium
A conversation with faculty members who will share insights into the development of their careers.
MODERATOR: Michael Glick, DMD
Kelly Jordan-Sciutto, PhD, Professor of Pathology, Associate Dean of Graduate Education
Frank Setzer, DMD, MS, PhD, Associate Professor of Endodontics
3:30 PM Break
3:45 PM PDM FACULTY PRESENTATION 2 – Arthur E. Corby Auditorium
MODERATOR: Neeraj Panchal, DDS, MD, MA
“Inter-individual Variability in Analgesic Response to Non-steroidal Anti-Inflammatory Drugs”
Katherine Theken, PharmD, PhD, Assistant Professor of Oral and Maxillofacial Surgery/Pharmacology
4:15 PM PDM FACULTY PRESENTATION 3 – Arthur E. Corby Auditorium
MODERATOR: Myra F. Laird, PhD
“Next-Generation Machining and Sintering Technologies for Ceramic Dental Restorations”
Yu Zhang, PhD, Professor, Department of Preventive and Restorative Sciences, Director for Restorative Research Laboratories for Microstructure Physics & Mechanics of Materials
5:00 PM Reception, Recognition and Awards – Fonseca Gardens
PDM RESEARCH DAY KEYNOTE SPEAKER
SUMITA BHADURI-MCINTOSH, MD, PhD
Professor, Pediatric Infectious Diseases
Depts. of Pediatrics & Molecular Genetics and Microbiology
UF Health Cancer Center
University of Florida
Sumita Bhaduri-McIntosh, MD, PhD, is a physician-scientist, Professor of Pediatrics, and former Chief of Pediatric Infectious Diseases at the University of Florida. She completed her medical training at B.J. Medical College in Pune, India, and earned a PhD in Molecular and Cell Biology from Hahnemann University.
Following a Pediatric Infectious Diseases fellowship at Yale University, she pursued advanced training in virology and immunology under the mentorship of Dr. I. George Miller. Dr. Bhaduri-McIntosh previously held faculty appointments at Yale University and Stony Brook University before joining the University of Florida as a tenured professor and Children’s Miracle Network Scholar. She also serves as the Editor-in-Chief of PLOS Pathogens.
Her research focuses on Epstein-Barr virus (EBV) interactions with B cells, investigating its lytic activation, viral transcription and replication, and immune evasion in driving B cell proliferation.
THE JOSEPH L. RABINOWITZ MEMORIAL LECTURE
MICHAIL LIONAKIS, MD, SCD
Senior Investigator Acting Chief, Laboratory of Host Immunity and Microbiome
Deputy Chief, Laboratory of Clinical Immunology & Microbiology
Chief, Fungal Pathogenesis Section, LCIM National Institute of Allergy & Infectious Diseases
National Institute of Health
Dr. Michail Lionakis is a physician-scientist and Chief of the Laboratory of Clinical Immunology & Microbiology at the National Institute of Allergy and Infectious Diseases (NIAID). His bench-to-bedside research studies the genetic and immune defects of human susceptibility to fungi and the cellular and molecular factors that regulate antifungal immunity.
Dr. Lionakis’ work has defined precise genetic, biochemical, immunologic, and cellular mechanisms that have led to immunotherapies. He identified interferonopathy as the driver of mucosal candidiasis and multiorgan autoimmunity in APECED and uncovered impaired microglial-neutrophil crosstalk as a key mechanism in brain candidiasis associated with CARD9 deficiency. Additionally, he has delineated novel inherited (CARD9 deficiency, STAT3 haploinsufficiency) and acquired (BTK and complement inhibitor-associated) immunodeficiencies that cause to fungal infections.
JOSEPH AND JOSEPHINE RABINOWITZ AWARD FOR EXCELLENCE IN RESEARCH
The Joseph and Josephine Rabinowitz Award for Excellence in Research was designed to help Penn Dental Medicine faculty undertake pilot projects that will enable them to successfully apply for extramural sources of funding. Designed through the lens of a researcher, this ongoing grant evaluates research proposals for their scholarly merit, creativity and innovation; the significance of the research in advancing scientific knowledge; the prospects for future extramural funding; the availability of alternate funding sources; and in the case of junior faculty, evidence that the applicant will be working as an independent investigator and forwarding of the School’s research objectives. It was under development as early as 1994 with the first award presented in 2002.
This award was endowed through the generosity of the late Dr. Joseph “Jose” Rabinowitz, an active member of the School’s biochemistry faculty for 29 years, and his wife, the late Dr. Josephine “Josy,” a fellow Penn alum. Josy’s PhD was in the field of education. Her strong endorsement of education and research provided a hand in the development of this grant. Jose was known for his research in lipid and steroid biochemistry, and made the seminal discovery that HMG CoA was a key intermediate in cholesterol biosynthesis. His research helped lead to the development of the important class of cholesterollowering drugs known as statins.
The Rabinowitz family continues to support the values and priorities of this award and congratulates its newest recipients.
2025 JOSEPH AND JOSEPHINE RABINOWITZ AWARD RECIPIENTS
Kathleen Boesze-Battaglia, PhD
Professor, Department of Basic and Translational Sciences
Effect of Western Diet on Retinal Lipoprotein Metabolism and Visual Function
Over a third of adults over the age of 60 in the U.S. experience significant vision loss, which results in decreased independence and also serves as a biomarker of decreased health span. Age-related retinal degeneration is the leading cause of such vision loss, affecting almost 200 million people worldwide. The Age-related Eye Disease Study (AREDS) and follow-up AREDS2 has shown an association between foods containing high fat dietary products, fried and refined food, and those enriched with red/processed meat, often referred to as a “Western-style” diet, with such retinal degeneration. Lipids contained in the Western diet are transported in the circulation and between cells in lipoprotein particles. In these studies, we will test our hypothesis that in the eye, local beta-lipoprotein (Blp) assembly and secretion protects the retina against diet-induced lipotoxicity and degeneration.
Katherine Theken, PharmD, PhD
Assistant Professor, Department Oral and Maxillofacial Surgery/Pharmacology
Sex Differences in Post-Surgical Pain and Analgesic Response
Pain is one of the most common complications following surgery. While this acute pain typically resolves within days to weeks after a procedure, some patients experience chronic post-surgical pain, which is often underdiagnosed and undertreated. Inadequate pain management in the perioperative period and female sex are important risk factors for the development of chronic post-surgical pain, but the mechanisms underlying these relationships are unknown. We have observed that women are more likely than men to require supplemental opioids after third molar extraction, indicating inadequate analgesic response to nonsteroidal anti-inflammatory drugs (NSAIDs). This project will investigate the mechanisms underlying sex differences in pain and analgesic response, focusing on neuroimmune interactions in a preclinical model of post-surgical pain.
Marco Tizzano, PhD
Associate Professor, Department Basic and Translational Sciences
The Bitter Taste Signaling Pathway in Gingival
Macrophages Participates in Anti-inflammatory and Bone Repairing Responses
Periodontal disease affects nearly 50% of US adults over age 30. We previously discovered taste cell-like solitary chemosensory cells in the gingiva (gSCCs) and preclinically demonstrated their protective antimicrobial function against periodontal bone loss. Recently, we observed the presence of the taste signaling pathway also in gingival macrophages (gMΦs). While gSCCs participate in the gingival epithelial barrier by promoting anti-microbial peptide release, gMΦs participate as 2nd level of protection by evoking anti-inflammatory response that promotes bone repair. With this proposal, we will determine the antiinflammatory role of gMΦs in response to bitter compounds in reducing periodontal bone loss. In sum, gMΦs and gSCCs are novel targets for the treatment of periodontal disease and show great potential for a preventive approach by a daily routine of oral care that includes the use of taste receptor activators (e.g. in toothpaste or mouthwash).
FACULTY PRESENTATIONS
Presentations
THE DARK SIDE OF TRAINED IMMUNITY
George Hajishengallis
Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine
A decade after the term ‘trained immunity’ (TRIM) was coined to reflect the long-lasting hyper-responsiveness of innate immune cells with an epigenetically imprinted ‘memory’ of earlier stimuli, our understanding has broadened to include the potential implications of TRIM in health and disease. Here, after summarizing the well-documented beneficial effects of TRIM against infections, I will discuss emerging evidence that TRIM is also a major underlying mechanism in chronic inflammationrelated disorders such as periodontitis, rheumatoid arthritis and cardiovascular disease.
Educational Objectives
• To learn that innate immunity can also build and retain immunological memory of past infectious or inflammatory challenges.
• To learn that inflammatory memory can aggravate osteoclastogenesis and bone loss
• To learn that inflammatory memory can link distinct inflammatory comorbidities
INTER-INDIVIDUAL VARIABILITY IN ANALGESIC RESPONSE TO NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
Katherine Theken
Oral & Maxillofacial Surgery, University of Pennsylvania School of Dental Medicine
Numerous clinical trials have shown that non-steroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of postsurgical pain following third molar extraction. However, there is substantial inter-individual variability in the analgesic response, with 20-30% of patients requiring opioids in addition to NSAIDs to achieve adequate pain relief. The use of precision medicine approaches to tailor analgesic therapy would enable oral surgeons to rationally prescribe opioids to only those patients who require them and avoid unnecessary opioid prescriptions in those patients who can achieve adequate pain relief with NSAIDs alone. This presentation will discuss ongoing research seeking to identify factors that contribute to inter-individual variability in analgesic response to NSAIDs, with the goal of optimizing post-surgical pain management while limiting unnecessary opioid prescriptions.
Educational Objectives
• List at least 3 factors that contribute to inter-individual variability in pain and analgesic response.
• Describe the mechanism of action of NSAIDs and opioids.
• Explain how precision medicine approaches could be applied to improve post-surgical pain management.
NEXT-GENERATION MACHINING AND SINTERING TECHNOLOGIES
FOR CERAMIC DENTAL RESTORATIONS
Yu Zhang
Preventive
and Restorative Sciences, University of Pennsylvania School of Dental Medicine
With rapid advances in material development and digital technology, time efficiency of dental workflow and fit accuracy of ceramic restorations are ever improving. Zirconia and lithia glass–ceramics are at the forefront of this advance. The trend in fabrication is to move from CAD/CAM grinding partially sintered/crystallized blocks to fully sintered/crystallized materials, thereby circumventing the need for post-machining heat treatment; or to drastically reduce the ceramic sintering time. In these endeavors, a better understanding of ceramic properties and innovative ductile-regime grinding (shaping) and ultrafast sintering (densification) technologies is paramount. Challenges facing the implementation of new technologies in the efficient development and production of high quality dental ceramic prostheses will be addressed.
Educational Objectives
• A facile understanding of the composition, microstructure, and properties of various classes of ceramic restorative materials for the digital workflow.
• The emerging grind-and-seat ceramic restorative systems without the need of any post-shaping heat treatment.
• Novel fabrication methodologies such as ductile grinding and ultrafast sintering offer the prospect of more efficient and longer lifetime ceramic restorations.
Dialogue
Kelly Jordan-Sciutto
Professor, Department of Oral Medicine
Kelly Jordan-Sciutto is Professor of pathology at the University of Pennsylvania. She completed a postdoc in neuropathology at the University of Pittsburgh and received her PhD in biochemistry and molecular biology from Thomas Jefferson University. Her research focuses on understanding how neuroinflammation and organellar stress contribute to neuronal dysfunction and loss in neurodegenerative diseases like HIV-associated brain injury, Alzheimer’s, and Parkinson’s.
Frank Setzer
Associate Professor, Department of Endodontics
Frank C Setzer received his dental and doctoral degree from FAU Erlangen-Nuremberg, Germany in 1995 and 1998; and his Endodontic specialty certificate, MSOB and DMD from the University of Pennsylvania in 2006, 2008, and 2010, respectively. He is currently an Associate Professor of Endodontics at the University of Pennsylvania, serving as Predoctoral Director in Endodontics. His research interests are the clinical detection, prognosis and assessment of periradicular pathology, in particular apical periodontitis, utilizing CBCT imaging and Artificial Intelligence, as well as endodontic microsurgery. Dr. Setzer is a Diplomate of the American Board of Endodontics ABE. He is Associate Editor for Journal of Endodontics, and lectures at national and international conferences.
FACULTY AND JUNIOR INVESTIGATOR POSTERS
*Junior Investigators include the following categories: Masters students, DScD students, Residents, Postdocs, Research Associates and Junior Faculty
RD-1
Induction of Functional Human MRGPRX2 in Tissue Mast Cells in Mice in Vivo
Yahia Abuhasan1, Sangita Sutradhar2
Hydar Ali2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-2
Targeting Inflammatory Chemokine Receptor in Fibroblasts to Reduce Eosinophilic Inflammation
Sara N. Aldosary1, Xianhong Yang1, Xiaoping Yang2, Stephen Prouty2, John Seykora2
Dana T. Graves1
University of Pennsylvania School of Dental Medicine, Department of Periodontics, 2University of Pennsylvania Perelman School of Medicine, Department of Dermatology
RD-3
Single-cell RNA Sequencing Analysis of the Impact of Diabetes on the Host Response in Bacteria-induced Periodontitis
Bushra Alghamdi1,2, Min Liu1, Debnath Rahul1,3, Afzali Hamideh1, Troka E. Michael4, Michael V. Gonzalez5, Xin Huang1, Kang I. Ko1
Dana T. Graves1
University of Pennsylvania School of Dental Medicine, Department of Periodontics, 2University of Pennsylvania School of Dental Medicine, Department of Endodontics, 3Assam Downtown University, Department of Paramedical Sciences, 4University of Pennsylvania School of Dental Medicine, 5University of Pennsylvania Perelman School of Medicine, Center for Cytokine Storm Treatment & Laboratory
RD-4
Sex Differences in PGE2 Production in Human Derived Neutrophils
Naser Alkandari1,2, Jonathan Bernal3, Stacey A. Secreto3,4, Steven Wang3, Neeraj Panchal3, Joseph Foote3, John Lankalis3, Brian P. Ford3 Katherine N. Theken3
University of Pennsylvania School of Dental Medicine, Department of Oral Medicine, 2Kuwait University Faculty of Dentistry, Department of Diagnostics, 3University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 4University of Pennsylvania School of Dental Medicine, Center for Clinical and Translational Research
RD-5
Protective Role of Bitter Taste Signaling Cascade in Modulating Pulpitis
Shahd Almasswary1, Ranhui Xi2, Bekir Karabucak1 Marco Tizzano3
1University of Pennsylvania School of Dental Medicine, Department of Endodontics, 2University of Pennsylvania School of Dental Medicine, Center for Clinical and Translational Research, 3University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-6
Targeting Herpes Simplex Virus
Glycoprotein D with Bispecific Antibodies: Expanding Therapeutic Horizons
Doina Atanasiu1, Wan Ting Saw1, Harvey M. Friedman2, Gary H. Cohen1
1University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2University of Pennsylvania Perelman School of Medicine, Infectious Disease Division
RD-7
Effect of the Membrane Proximal Region on the Antigenic Structure of Herpes Simplex Virus Glycoproteins gD, gC, and gE
Tina M. Cairns1, Doina Atanasiu1, Wan Ting Saw1, Harvey M. Friedman2, Gary H. Cohen1
1University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2University of Pennsylvania Perelman School of Medicine, Infectious Disease Division
RD-8
A Newly Identified Foramen of the Dorsum Sellae in Humans and Non-human Primates
Stephanie L. Canington1, Zana R. Sims2, Alexandria L. Sambrano3, Christian A. Mastroianni4, Myra F. Laird1
1University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2University of Minnesota, Ecology, Evolution, & Behavior, 3University of Pennsylvania, Anthropology, 4University of Pennsylvania School of Dental Medicine
RD-9
Mechanical Regulation of Dendritic Cell Activation
Yu-Chang Chen1, Nghi M. Tran2, Shuchen Zhang3, Hardik Makaar3,4, Kyle H. Vining1,3,4
1University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 2University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 3University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 4University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry (CiPD)
RD-10
Extracellular Matrix Stiffness Dependent Behavior of Dental Pulp Stem Cells
BingLing Chen1, Nghi M. Tran2, Hardik Makaar3,4, Yu-Chang Chen5, Justin Jisu Lim6, Yifan Lin7, Changyue Xue8
Kyle H. Vining3,4,5
1University of Pennsylvania School of Arts and Sciences, Department of Biology, 2University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 3University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 4University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry (CiPD), 5University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 6University of Toronto, Department of Molecular Genetics, 7University of Hong Kong, Division of Paediatric Dentistry and Orthodontics, 8Affiliated Stomatological Hospital of Nanjing Medical University, Department of Implant Dentistry
RD-11
An Inspirational Patient Encounter
Stephanie Fernandez-Guckes, Rena Katsev University of Pennsylvania School of Dental Medicine
RD-12
Training Dentists to Provide Innovative Care for Individuals with Disabilities
Robert W. Frare1, Marc Henschel2
1University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 2University of Pennsylvania School of Dental Medicine, Department of Community Oral Health
RD-13
A High-fat Diet Exacerbates Defects in Lipid Processing and Visual Function in the RPEΔMttp Mouse
Catharina R. Grubaugh1, Brent Bell2
Kathleen Boesze-Battaglia1
University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2Scheie Eye Institute, University of Pennsylvania Perelman School of Medicine, F.M Kirby Center for Molecular Ophthalmology
RD-14
INPP5E in Macrophages Negatively Regulates Osteoclastogenesis and Inflammatory Signaling During Bone Development
Abdulaziz Hakeem, Shuting Yang, Yang Yang, Malihatosadat Gholam Zadeh
Shuying Yang
University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-15
Dasatinib and Quercetin Reduce Senescence Markers in Gingival Keratinocytes
Megi G. Hysa1, Xia-Juan Xia2, Kantapon Rattanaprukskul3, Samuel F. Suslavich4, Ming Jiang5
Esra S. Sahingur2
University of Pennsylvania College of Arts & Sciences, Department of Biology, 2University of Pennsylvania School of Dental Medicine, Department of Periodontics 3Chulalongkorn University, Department of Peridontology 4University of Pennsylvania School of Dental Medicine 5Penn Medicine, Deparment of Pathology and Laboratory Medicine
RD-16
Investigating Gummy-Based Anti-Biofilm Agents: Rheological Properties and Dental Morphology
Speline Irakoze1, Hyun Koo2,3, Daeyeon Lee4, Jessica Silva Peixoto Bem2,3,5
Myra F. Laird6
University of Pennsylvania School of Dental Medicine 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics, 3University of Pennsylvania School of Dental Medicine, Center
for Innovation and Precision Dentistry, 4University of Pennsylvania School of Engineering and Applied Science, Chemical and Biomolecular Engineering, 5University of São Paulo, Ribeirão Preto School of Dentistry 6University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-17
Radiation Induced Trismus in Maxillofacial Reconstruction: Systematic Review and Case Studies
Diana H. Joo1, Brian M. Chang1,2,3,4, Nupur Patel1,5, Yoonhyuk Huh6
1University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 3Hospital of University of Pennsylvania, Maxillofacial Prosthodontics, 4Hospital of University of Pennsylvania, The Penn Center for Innovative & Personalized Oral Rehabilitation, 5University of Pennsylvania School of Dental Medicine, Advanced Education Program in Prosthodontics, 6Gangneung Wonju National University, Department of Prosthodontics
RD-18
Collagen Fiber Self-Assembly in Viscoelastic Polysaccharide Matrices
Fatemeh T. Joorabi1, Nicholas J. Derr2, Zecheng Li3, Bryan A. Nerger4,5, Chris H. Rycroft6,7, David J. Mooney4,5, Kyle H. Vining1,8,9
1University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 2Massachusetts Institute of Technology, 3University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 4Harvard University, John A. Paulson School of Engineering and Applied Sciences, 5Harvard University, Wyss Institute for Biologically Inspired Engineering, 6University of Wisconsin–Madison, Department of Mathematics, 7Lawrence Berkeley Laboratory, Computational Research Division, 8University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 9University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry
RD-19
Digital Dentistry and AI for Complex Multidisciplinary Oral Rehabilitation
Rena Katsev1, Stephanie Fernandez-Guckes1 Patrice Ierardi2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences
RD-20
Impact of PERK Genetic Variants on the Serum Cytokine Profile of People with HIV on Antiretroviral Therapy: A Racially Stratified Analysis
Afnan Khalifah1, Temitope T. Omolehinwa2 Cagla Akay-Espinoza2, Kelly Jordan-Sciutto2
1University of Pennsylvania School of Dental Medicine, Department of Periodontics, 2University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-21
Gingival Bleeding Exacerbates Iron Burden and Induces Ferroptosis Features in Murine Periodontitis
William S. Kim1, Debnath Rahul1,2 Kang I. Ko1
1University of Pennsylvania School of Dental Medicine, Department of Periodontics, 2Assam Downtown University, Department of Paramedical Sciences
RD-22
Transcriptome Profiling of Human Trophoblast Stem Cells in Comparison with SHED for Mesenchymal Lineage Differentiation
Zhangyi Li1
Chider Chen2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-23
DEL-1 ss a Novel Endogenous Senolytic Protein that Inhibits Senescenceassociated Bone Loss
Jong-Hyung Lim1, Kridtapat Sirisereephap2, Tomoki Maekawa2, Kyoung-Jin Chung3
Triantafyllos Chavakis4, George Hajishengallis1
1University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2Niigata University, 3Technische Universität Dresden, 4Technische Universität Dresden, Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine
RD-25
Activation of the Bitter Taste Signaling Pathway in the Gingiva Attenuates Alveolar Bone Loss in Mice
Jiaxin Liu, Ranhui Xi
Marco Tizzano
University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-26
Mechanical Regulation of Inflammation in Periodontal Health and Disease
Hardik Makaar1,2, Nghi M. Tran3, Kang I. Ko4, YuChang Chen5, Rebecca G. Wells6, Kyle H. Vining1,2,5
University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 2University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry (CiPD), 3University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 4University of Pennsylvania School of Dental Medicine, Department of Periodontics, 5University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 6University of Pennsylvania Perelman School of Medicine
RD-27
Biomechanics of Mastication: Occlusal Forces and Stress Distribution on Teeth
Pratik Nag1, Stephanie L. Canington2, Myra F. Laird2, Geelsu Hwang1,3
University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences 3School of Engineering and Applied Sciences, Center for Innovation & Precision Dentistry
RD-28
Development of a 3D Tumor Model Using Chimeric Spheroids
Amber Nguyen1, Kyle H. Vining2,3,4, Mia Ruiz5, Fatemeh T. Joorabi3, Dayoon Chang5
University of Pennsylvania College of Arts & Sciences, Department of Biology, 2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 3University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 4University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry, 5University of Pennsylvania School of Dental Medicine
RD-29
Trained Immunity as a Potential Causative Link in the Mash-periodontitis Comorbidities
Gundappa Saha1, Triantafyllos Chavakis2, George Hajishengallis1
1University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2Technische Universität Dresden, Institute for Clinical Chemistry and Laboratory Medicine, Faculty of Medicine
RD-30
Dynamics of Interkingdom Biofilm Growth and Host Responses in A Mouth-On-A-Chip Model
Jessica Silva Peixoto Bem1,2,3, Mousa Younesi1,4, Dongeun Huh1,4, Hyun Koo1,3
1University of Pennsylvania School of Dental Medicine, Center for Innovation and Precision Dentistry, 2University of São Paulo, Ribeirão Preto School of Dentistry, 3University of Pennsylvania School of Dental Medicine, Department of Orthodontics, 4University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering
RD-31
Oral and Maxillofacial Surgeon Accuracy in Anticipating Supplemental Opioid Use Following Third Molar Extraction
Sierra R. van den Dries
Neeraj Panchal, Katherine N. Theken
University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology,
RD-32
Myeloid-Specific Deletion of Lipid Phosphate Phosphatase 3 Exacerbates Inflammation and Experimental Periodontitis
Xudong Wang
University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-33
A Novel Taste Bud Structure in the Mandibular Sublingual Caruncles of Mice
Ranhui Xi1, Jiaxin Liu1, Shahd Almasswary2, Marco Tizzano1
1University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 2University of Pennsylvania School of Dental Medicine, Department of Endodontics
RD-34
Enhanced Prevention of Cariogenic Biofilms Through the Targeted Delivery of Enzymes
Ilchul Yoon1, Hyejoo Kim1, Geelsu Hwang1,2
1University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 2School of Engineering and Applied Sciences, Center for Innovation & Precision Dentistry
RD-35
Transplantation of SHED Ameliorates Gliadin-Induced Celiac Phenotypes via PD-L1 Mediated T Cell Apoptosis
Mehrnaz Zakershahrak1
Chider Chen2
1University of Pennsylvania School of Dental Medicine, Department of Endodontics, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-36
Porous, Compressible Alginate Cryogels for Macromolecular Loading
Kexin Zhang1, Yuchen Jiang1
Kyle H. Vining1,2,3
1University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 3University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry
STUDENT POSTERS
RESEARCH HONORS
RD-37
What is the Role of the Autonomic Nervous System in Mediating Pain and Analgesic Response in Acute Dental Pain?
Bryanna Bravo1
Katherine N. Theken2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-38
Dissecting Elastic Mechanics in Oral Cancer Tumor Regulation
Dayoon Chang1, Fatemeh T. Joorabi2, Yu-Chang Chen2, Amanda Bluem3
Kyle H. Vining1,2,4
University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 3University of Pennsylvania School of Engineering and Applied Sciences, Department of Bioengineering, 4University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry
RD-39
Mapping of Herpes Simplex Virus Glycoprotein C Antibodies
Zilin Guo1, Doina Atanasiu2, Harvey M. Friedman3
Gary H. Cohen2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 3University of Pennsylvania Perelman School of Medicine, Infectious Disease Division
RD-40
Investigating the Effect of Boldine on Paclitaxel-Treated Axons In Vitro
Gaurav Gupta1, Cameron Casenhiser1, Qunzhou Zhang2, Justin C. Burrell2,3
Katherine N. Theken2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 3University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-41
pH-Responsive Zif-8 Precisely Induces Apoptosis of Oral Cancer Cells
Jessica Hao1, Mehrnaz Zakershahrak2, Fusun Ozer3 Chider Chen4
1University of Pennsylvania School of Dental Medicine 2University of Pennsylvania School of Dental Medicine, Department of Endodontics 3University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences 4University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology,
RD-42
Development and Characterization of the Properties of Novel 3.5% Yttria Stabilized Zirconia
Michelle Joung1, Li Zheng2 Yu Zhang3
1University of Pennsylvania School of Dental Medicine 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 3University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences
RD-43
Acetaldehyde-driven DNA Damage, Fanconi Anemia, And Oral Microbiome Carcinogenesis
Yesul Kang1, Camila Furquim2,3, Rima Amen2, Lynn Martin2 Flavia Teles2
1University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 3University of Guarulhos, Department of Periodontology and Oral Implantology, Dental Research Division
RD-44
Targeted Delivery of STAT3-siRNA in Lipid Nanoparticles for Periodontal Disease Therapy
Yuantong Li1, Doris Chen1, Shuchen Zhang2, Yu-Chang Chen3, Jingyi Liu4, Hardik Makaar2,5
Kyle H. Vining2,3,5
University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 3University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 4University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 5University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry (CiPD)
RD-45
Dissecting the Inflammatory Milieu of Diabetic Wounds with Single-Cell RNA Sequencing: Anti-S100a11 Identified as a Novel Pro-Healing Treatment
Troka E. Michael1, Afzali Hamideh2, Michael V. Gonzalez3
Dana T. Graves2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Periodontics, 3University of Pennsylvania Perelman School of Medicine, Center for Cytokine Storm Treatment & Laboratory
RD-46
Simulating the Effects of Nocturnal Bruxism on Clear Aligners
Tucker Sprayberry1, Stephanie L. Canington2, Madeline Gustaf3, Hannah Jaghab3, Kristin L. Krueger3
Myra F. Laird2
University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 3Loyola University Chicago, Department of Anthropology
STUDENT POSTERS
RD-47
Enhancing the Mechanical and Surface Properties of 3D-Printed 5YSZ Through Glass Infiltration
Kyler R. Van Evera1, Li Zheng2
Yu Zhang3
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 3University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences
RD-48
Metformin and Melatonin-Induced ER Stress and Autophagy Activation in OSCC
Jessica Winarto1, Angelina Debbas1, Jacquelyn Cuccurullo1, Shihong Shi2
James C. Gates2, Qunzhou Zhang2, Anh Le2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-51
Does Sleep Apnea Affect Implant Longevity?
Bryce A. Brandfon1
Brian P. Ford2,3
1University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 3Philadelphia VA Medical Center
RD-52
Do Post-Operative Opioid Prescriptions Prevent “Return for Pain” Appointments Following Bilateral Sinus Augmentation Procedures?
John Button1
Brian P. Ford2,3, Neeraj Panchal2
1University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 3Philadelphia VA Medical Center
RD-53
DMD STUDENT SUMMER
RESEARCH
RD-49
The Expression of NF-kB in Mesenchymal Stem Cells during Tensile Force-Induced Bone Remodeling
Sydney Ariel Bohm1
Hyeran H. Jeon2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics
RD-50
Impact of BTO on Adhesion and Transcriptomics
Adam J. Bouhamdan1, Hyejoo Kim2
Geelsu Hwang2,3
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 3School of Engineering and Applied Sciences, Center for Innovation & Precision Dentistry
IL33+ Fibroblasts Activate Regulatory T Cells to Promote Angiogenesis in Oral Wound Healing
Zhaoxu Chen1, William S. Kim2, Zikeng Huang3, Debnath Rahul2,4, Kawintip Prasongyuenyong2, Brett P. DerGarbedian5, Thao Do2 Kang I. Ko2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Periodontics, 3University of Minnesota School of Dentistry, 4Assam Downtown University, Department of Paramedical Sciences, 5Cooper University Hospital, Department of Emergency Medicine
RD-54
Relationship Between Single Nucleotide Polymorphisms in OPRM1 and COMT and Analgesic Response To Ibuprofen Following Third Molar Extraction
Brandon L. Chin1
Katherine N. Theken2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-55
Analysis of Adolescent Patient Perception of HPV and COVID-19 Vaccinations in the Dental Setting in Los Angeles, California
Ryan Elder1
Katherine France2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-56
The Effect of NF-kB in Mesenchymal Stem Cells in Osteoclast Formation During Mechanical Force-Induced Maxillary Expansion
Grace Gong1
Hyeran H. Jeon2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics
RD-57
Efficacy of Biologic Agents FRIL and PG1 in Endodontic Treatment: A Targeted Approach Against Biofilm-Forming Pathogens
Anna-Maria Haddad1, Mira-Belle Haddad1, Geetanjali Wakade1, Dana Mominkhan2
Henry Daniell3, Bekir Karabucak2, Flavia Teles3
University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Endodontics, 3University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-58
Patient Attitudes on Dentists Administering HPV and HSV Vaccines
Matthew Halpert1, Jasmine Shokri1, Daphne Hicyilmaz2, Jinbo Niu3, Tamara J. Cadet3
Katherine France4
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania College of Arts & Sciences
3University of Pennsylvania School of Social Policy and Practice 4University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-59
Cytolethal Distending Toxin Regulation on Osteoclastogenesis
Nam Le1
Taewan Kim2, Kathleen Boesze-Battaglia3
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Periodontics, 3University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-60
Dentistry and Mental Health Diagnoses: Does PTSD/Depression Affect Implants?
Emma Linn1, Bryce A. Brandfon1, Harrison Selznick1, Mani Sandhu1, Kevin C. Lee2
Brian Ford3,4
University of Pennsylvania School of Dental Medicine, 2University of Washington School of Dentistry, Department of Oral and Maxillofacial Surgery
3University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 4Philadelphia VA Medical Center
RD-61
Sex-Dependent Effects of Gut Microbial Metabolites in Acute Dental Pain
Elisa R. Lipkin1, Gina N. Chryssofos1, Stacey A. Secreto2,3, Steven Wang3, Neeraj Panchal3, Rania A. Habib3, Brian P. Ford3,4, Elliot V. Hersh3
Katherine N. Theken3
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Center for Clinical and Translational Research, 3University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 4Philadelphia VA Medical Center
RD-62
Predicting Voluntary Bite Force from Craniofacial Morphology
Christian A. Mastroianni1, Stephanie L. Canington2, Megan A. Holmes3, Andrea B. Taylor4, Claire E. Terhune5
Myra F. Laird2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences 3Duke School of Medicine, Family Medicine and Community Health, 4Touro College of Osteopathic Medicine, Basic Science, 5University of Arkansas, Anthropology
RD-63
Assessment of Lipid Dysregulation Pathways in Human Choroideremia Patients and CHM^null/wt Mouse
Marco McGowan1, Eric Larson2
Kathleen Boesze-Battaglia2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-64
Demineralization Effect of Orthodontic Brackets and Clear Aligner Therapy on Isolated Teeth: An In Vitro Study
Isabella M. Orup1
Wenjing Yu2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics
RD-65
Comparison of the Osteogenesis in the Midpalatal Suture During Maxillary Expansion Between Young and MiddleAged Mice
Caroline Palmer1
Hyeran H. Jeon2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics
RD-66
Evaluating the Role of Antihypertensives and Systemic Risk Factors in PeriImplantitis
Mani Sandhu1
Brian P. Ford2,3
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 3Philadelphia VA Medical Center
RD-67
Investigating the Impact of Serum 25(OH) Vitamin D Levels on Implant Survival Rates
Harrison Selznick1
Brian P. Ford2,3
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 3Philadelphia VA Medical Center
RD-68
Psychological Predictors of Postoperative Pain in Third Molar Extraction Patients
Emily F. Shekhtman1, Stacey A. Secreto2,3, Steven Wang3, Neeraj Panchal3, Rania A. Habib3, Brian P. Ford3,4, Elliot V. Hersh3
Katherine N. Theken3
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Center for Clinical and Translational Research, 3University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology, 4Philadelphia VA Medical Center
RD-69
Patient Knowledge and Perception on Dentists’ Role in HPV Vaccination
Jasmine Shokri1, Daphne Hicyilmaz2, Matthew Halpert1, Meigan Niu1, Tamara J. Cadet3
Katherine France4
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania College of Arts & Sciences, 3University of Pennsylvania School of Social Policy and Practice, 4University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-70
Dasatinib and Quercetin Intervention Mitigates Gingival Senescence and Inflammation
Samuel F. Suslavich1, Kantapon Rattanaprukskul2, Xia-Juan Xia3, Megi G. Hysa4
Esra S. Sahingur3
University of Pennsylvania School of Dental Medicine 2Chulalongkorn University, Department of Peridontology 3University of Pennsylvania School of Dental Medicine, Department of Periodontics
4University of Pennsylvania College of Arts & Sciences, Department of Biology
STUDENT POSTERS
RD-71
Bone Marrow Adipocytes Regulate Osteoclastogenesis via Cxcl12Cxcr4 Signaling
Winslow Wanglee1
Chider Chen2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-72
An Evaluation of Why Patients with Special Health Care Needs Have Not Returned for Care: Barriers to Care and Their Effect On Patients’ Continuity of Care
Felicia P. Wong1
Dr. Alicia A. Risner-Bauman2
University of Pennsylvania School of Dental Medicine
2University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-75
Effect of NF-kB in Mesenchymal Stem Cells During Mechanical Force-induced Bone Remodeling: MicroCT Analysis
Lindsay H. Fisher1
Hyeran H. Jeon2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics
RD-76
Grinding out the Details: Validating Occlusal Topography Precision in Dental Wear Analyses
Shahd L. Habeb1, Stephanie L. Canington2, Tucker Sprayberry1, Kristin L. Krueger3, Guilherme Madureira3
Myra F. Laird2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences, 3Loyola University Chicago, Department of Anthropology
RD-79
Digital Smile Design for Precision and Predictability in Anterior Esthetic Restorations
Arjun Kini1, Harshiv Karia2, Man Sing Cheung2, Victor Iradi2, Glenn Rochlen2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences
RD-80
Trade-off of Bite Force and Gape in Tupaia Belangeri
Katie R. Lapinski1, Emily E. Meyer2, Mike J. Arcaro3
Myra F. Laird4
University of Pennsylvania School of Dental Medicine, 2Perelman School of Medicine, Department of Neuroscience, 3University of Pennsylvania, Department of Psychology, 4University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
RD-81
DMD STUDENT
OTHER RESEARCH
RD-73
Reconstruction of Tongue After SCC: Advances, Challenges and Future Direction
Pooja Ahluwalia
University of Pennsylvania School of Dental Medicine
RD-74
Assessment of Condylar Changes in Patients with Degenerative Joint Disease of the TMJ After Stabilizing Splint Therapy: A Retrospective CBCT Study
Nawal F. Dairi1, Sara Steinbaum2, Anabel Kelso3 Wenjing Yu2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics, 3Center for Clinical Epidemiology and Biostatistics
RD-77
A Brief Summary of the Advantages and Disadvantages of Conventional Versus Digital Impression Techniques for the Fabrication of Space Maintainers –A Review
Nader Hanna1, Arjun Kini1, Lauren Yap2 Evlambia Hajishengalis2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Clinical Pediatric Dentistry
RD-78
A Three-Dimensional Analysis of the Antegonial Notch in Relationship to Craniofacial Morphology in Humans
Celine J. Jarvis1, Myra F. Laird2, Stephanie L. Canington2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Basic and Translational Sciences
Oral Health Promotion and Prevention Project in Populations Affected by Drug Use in Kensington, Pennsylvania: A Comprehensive Data-Driven Approach
Maria F. Leal
University of Pennsylvania School of Dental Medicine
RD-82
Matrix Stiffness Affects
Immunomodulatory Functions of Dental Pulp Stem Cells Under Lipopolysaccharide Exposure
Myung Jin Lee1, Nghi M. Tran2, Yu-Chang Chen3
Kyle H. Vining1,3,4
University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences, 2University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 3University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 4University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry
RD-83
Shear Bond Strength of Two Universal Adhesives to Dentin: An In Vitro
Comparative Study
Allison Liu1, Brandley Tanelus1, Asha Sunkara2
Fusun Ozer2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences
RD-84
Enhancing Sleep Quality: Evaluating the Efficacy of Mandibular Devices for Sleep Apnea Treatment
Mariah Newton1
Roopali Kulkarni2, Katherine France2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-85
Nociceptor Neurons Facilitate Orthodontic Tooth Movement via Piezo2 in Mice
Ghazaal Parastooei1, Xuguang Nie2, Sheng Wang2, Sinu Kumari2, Omar Elnabawi3, Eung-Kwon Pae3, Ching Chang Ko4, Yasaman Abbasi5, Man Kyo Chung2
University of Pennsylvania School of Dental Medicine, 2University of Maryland School of Dentistry, Department of Neural and Pain Sciences, 3University of Maryland School of Dentistry, Department of Orthodontics and Pediatric Dentistry, 4The Ohio State University School of Dentistry, Department of Orthodontics, 5University of Maryland School of Dentistry Program in Dental Biomedical Sciences
RD-86
The Role of NF-kB in Mesenchymal Stem Cells During the Mechanical Force-induced Bone Remodeling: MSC Proliferation
Kyungjoon Park1, Christopher S. Kim1
Hyeran H. Jeon2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Orthodontics
RD-87
Prognostic Significance of Cortactin Expression in Oral Squamous Cell Carcinoma (OSCC): A Systematic Review
Mugdha Raut1
James C. Gates2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-88
Relationship Between Pain Expectation in Psychometric Questionnaire in Patients Undergoing Third-Molar Extractions
Sruti R. Sailam
University of Pennsylvania School of Dental Medicine
RD-89
Adolescent Perspectives on HPV and COVID-19 Vaccine Administration: Evaluating Dental Providers as Vaccinators
Dimi M. Schweitzer1, Jinbo Niu2, Daphne Hicyilmaz3, Tamara J. Cadet3
Katherine France4
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Social Policy and Practice, 3University of Pennsylvania College of Arts & Sciences 4University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-90
Accessibility to Oral Hygiene Products in Diverse Populations: An Investigation into the Oral Health Literacy and Practices of Medicaid Beneficiaries
Alexandra Sehne1
Roopali Kulkarni2
1University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral Medicine
RD-91
The Role of Mechanoregulation on DPSC Differentiation and Regenerative Capacity
Heewon (Karen) Sohn1, Yu-Chang Chen2, Nghi M. Tran3
Kyle H. Vining2,4,5
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Engineering and Applied Science, Department of Materials Science and Engineering, 3University of Pennsylvania School of Engineering and Applied Science, Department of Bioengineering, 4University of Pennsylvania School of Dental Medicine, Center for Innovation & Precision Dentistry, 5University of Pennsylvania School of Dental Medicine, Department of Preventive and Restorative Sciences
RD-92
Review of HLA levels in Oral Pre-Malignant Lesions
Mehar Soni1, Bryce DeSantis1
James C. Gates2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Department of Oral & Maxillofacial Surgery / Pharmacology
RD-94
Impact of Long-Term vs. Short-Term Antiretroviral Therapy on Salivary Osteoprotegerin Levels in Women Living with HIV
Shira L. Wald1, Anil Kumar2
Modupe Coker2
University of Pennsylvania School of Dental Medicine, 2University of Pennsylvania School of Dental Medicine, Center for Clinical and Translational Research