Hien Hoang Student pharmacist Spring 2022
LICORICE https://www.google.com/search?q=licorice+plant&tbm=isch&ictx=1&tbs=rimg:CY46LRmU459yIgiOOi 0ZlOOfcioSCY46LRmU459yERH11Gz4c1tq&hl=en&sa=X&ved=2ahUKEwi625yF4Kz2AhXog2oFHQ 05BFUQiRx6BAgAEAQ&biw=928&bih=735
Scientific Name: Glycyrrhiza glabra Common Names: Bois doux, Gan Cao, Glycyrrhizae extractum, crudum, Glycyrrhizae radix, Kanza.
Background/history: Licorice comes
Dosage Forms: Licorice root comes with
from the juice of the root of the plant name Glycyrrhiza Glabra. Licorice with the name of Liquorice has been found in 2300BC. It has been used in the ancient by Chinese people as a medicine. Now a day, they grow in North Africa, across the Middle East and to China. Today, Licorice is used as sweetener, supplement, oil and gel. Besides, people use it as tea.
vary forms, including chewing gum, chewing tobacco, deglycyrrhizinated chews, extract, intravenous solution, and tea.
Pharmacology/mechanism of action and common uses: Licorice contains an active metabolite is Glycyrrhetic acid. It inhibits the enzyme 11-Bhydroxysteroid dehydrogenase enzyme type 2 with a resultant cortisol-induced mineralocorticoid effect and the tendency towards the elevation of sodium and reduction of potassium levels. Licorice also used to kill MRSA via the disruption of the membrane permeability and the proton motive force. Today, Licorice is used to treat hepatitis, viral infections in adults and pediatric. Especially, it can treat dental care in children.
Typical Dosing: Ulcer and Gastritis: 1.5 to 3g daily Peptic Ulcer: 380 to 760 ml TID Upper respiratory tract: 0.5 to 1g daily General use root, oral: 1 to 5g TID for 6 weeks General use extract: 2 to 4ml TID Skin: 2% for 2 weeks
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