The presence of COVID in our community has disrupted the lives of every single Australian. As the national voice of the health and medical research sector we have committed to understanding the specific impact on our health and medical researchers. In May last year we conducted the first survey and identified the short-term effects of COVID-19 on health and medical research community. When this survey was conducted at the end of 2020, most of Australia was relatively free of COVID-19. There was the hope of vaccines arriving in the new year and a swift transition to a post COVID normal. Since then, new waves of COVID-19 have swept the globe, once again placing health systems under great pressure and greatly impacting our daily lives and work. The findings of this second survey of researchers remain as relevant as several months ago, and it is all the more important that we act on the lessons it gives us.