The rapid process of urbanization today represents an unprecedented challenge that will seemingly change the notion of the future. By 2050, more than 65% of the world's population are expected to live in cities. Buildings will undoubtedly change its course in the next 32 years to meet the living demands. Unlocking The Default III: Reshaping The Future Through Bio-Inspired Design unfolds the different possibilities of interjecting 'wonders of the nature' in engaging with the uncertainties and complexities of the future.