POZ September 2017

Page 1


WHAT IS GENVOYAÂŽ? GENVOYA is a 1-pill, once-a-day prescription medicine used to treat HIV-1 in people 12 years and older who weigh at least 77 pounds. It can either be used in people who are starting HIV-1 treatment and have never taken HIV-1 medicines before, or people who are replacing their current HIV-1 medicines and whose healthcare provider determines they meet certain requirements. These include having an undetectable viral load (less than 50 copies/mL) for 6 months or more on their current HIV-1 treatment. GENVOYA combines 4 medicines into 1 pill taken once a day with food. GENVOYA is a complete HIV-1 treatment and should not be used with other HIV-1 medicines. GENVOYA does not cure HIV-1 infection or AIDS. To control HIV-1 infection and decrease HIV-related illnesses, you must keep taking GENVOYA. Ask your healthcare provider if you have questions about how to reduce the risk of passing HIV-1 to others. Always practice safer sex and use condoms to lower the chance QH UGZWCN EQPVCEV YKVJ DQF[ Ćƒ WKFU 0GXGT TGWUG QT UJCTG PGGFNGU QT QVJGT KVGOU VJCV JCXG DQF[ Ćƒ WKFU QP VJGO

IMPORTANT SAFETY INFORMATION What is the most important information I should know about GENVOYA? GENVOYA may cause serious side effects: • Worsening of hepatitis B (HBV) infection. GENVOYA is not approved to treat HBV. If you have both HIV-1 and HBV and stop taking GENVOYA, your HBV may suddenly get worse. Do not stop taking GENVOYA YKVJQWV Ƃ TUV VCNMKPI VQ [QWT JGCNVJECTG RTQXKFGT CU VJG[ will need to monitor your health. Who should not take GENVOYA? Do not take GENVOYA if you take: • Certain prescription medicines for other conditions. It is important to ask your healthcare provider or pharmacist about medicines that should not be taken with GENVOYA. Do not start a new medicine without telling your healthcare provider. • The herbal supplement St. John’s wort. • Any other medicines to treat HIV-1 infection. What are the other possible side effects of GENVOYA? Serious side effects of GENVOYA may also include: • Changes in your immune system. Your immune U[UVGO OC[ IGV UVTQPIGT CPF DGIKP VQ Ƃ IJV KPHGEVKQPU Tell your healthcare provider if you have any new symptoms after you start taking GENVOYA.

• Kidney problems, including kidney failure. Your healthcare provider should do blood and urine tests to check your kidneys. If you develop new or worse kidney problems, they may tell you to stop taking GENVOYA. • Too much lactic acid in your blood (lactic acidosis), which is a serious but rare medical emergency that can lead to death. Tell your healthcare provider right away if you get these symptoms: weakness or being more tired than usual, unusual muscle pain, being short of breath or fast breathing, stomach pain with nausea and vomiting, cold or blue hands and feet, feel dizzy or lightheaded, or a fast or abnormal heartbeat. • Severe liver problems, which in rare cases can lead to death. Tell your healthcare provider right away if you get these symptoms: skin or the white part of your eyes turns yellow, dark “tea-coloredâ€? urine, light-colored stools, loss of appetite for several days or longer, nausea, or stomach-area pain. The most common side effect of GENVOYA is nausea. Tell your healthcare provider if you have any side effects that bother you or don’t go away. What should I tell my healthcare provider before taking GENVOYA? • All your health problems. Be sure to tell your healthcare provider if you have or have had any kidney or liver problems, including hepatitis virus infection. • All the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how GENVOYA works. Keep a list of all your medicines and show it to your healthcare provider and pharmacist. Ask your healthcare provider if it is safe to take GENVOYA with all of your other medicines. • If you take antacids. Take antacids at least 2 hours before or after you take GENVOYA. • If you are pregnant or plan to become pregnant. It is not known if GENVOYA can harm your unborn baby. Tell your healthcare provider if you become pregnant while taking GENVOYA. • If you are breastfeeding (nursing) or plan to breastfeed. Do not breastfeed. HIV-1 can be passed to the baby in breast milk. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Please see Important Facts about GENVOYA, including important warnings, on the following page.

Ask your healthcare provider if GENVOYA is right for you.

GENVOYA.com


GENVOYA does not cure HIV-1 or AIDS.

SHOW YOUR Take care of what matters most—you. GENVOYA is a 1-pill, once-a-day complete HIV-1 treatment for people who are either new to treatment or people whose healthcare provider determines they can replace their current HIV-1 medicines with GENVOYA.


IMPORTANT FACTS WHAT IS GENVOYAÂŽ? GENVOYA is a 1-pill, once-a-day prescription medicine

( used ) in people 12 years and older who jen-VOY-uh to treat HIV-1

weigh at least 77 pounds. It can either be used in people who are starting HIV-1 treatment and have never taken MOST IMPORTANT INFORMATION ABOUT GENVOYA HIV-1 medicines before, or people who are replacing their current HIV-1 and side whose healthcare provider GENVOYA maymedicines cause serious effects, including: determines they meet certain requirements. These include • Worsening of hepatitis B (HBV) infection. GENVOYA is not having an undetectable viral load (less than 50 copies/mL) approved to treat HBV. If you have both HIV-1 and HBV, your for 6 months or more theirif current HBV may suddenly geton worse you stopHIV-1 takingtreatment. GENVOYA. GENVOYA combines 4 medicines into pill taken once a Do not stop taking GENVOYA without first1talking to your day with food. GENVOYA a complete HIV-1 treatment healthcare provider, as theyiswill need to check your health regularly fornot several months. and should be used with other HIV-1 medicines. GENVOYA does not cure HIV-1 infection or AIDS. ABOUT GENVOYA To control HIV-1 infection and decrease HIV-related illnesses, you must keep taking GENVOYA. Ask your • GENVOYA is a prescription medicine used to treat HIV-1 in healthcare provider if you have questions about how 12 years of age and older HIV-1 who weigh at leastAlways 77 pounds topeople reduce the risk of passing to others. and have never taken HIV-1 medicines before. GENVOYA can practice safer sex and use condoms to lower the chance also be used to replace current HIV-1 medicines for some QH UGZWCN EQPVCEV YKVJ DQF[ ĆƒWKFU 0GXGT TGWUG QT UJCTG people who have an undetectable viral load (less than 50 PGGFNGU QT QVJGT KVGOU VJCV JCXG DQF[ ĆƒWKFU QP VJGO copies/mL of virus in their blood), and have been on the same HIV-1 medicines for at least 6 months and have never failed IMPORTANT SAFETY INFORMATION HIV-1 treatment, and whose healthcare provider determines that they meetmost certain other requirements. What is the important information I should •know GENVOYA does not cure HIV-1 or AIDS. Ask your healthcare about GENVOYA?

provider about how to prevent passing HIV-1 to others.

GENVOYA may cause serious side effects: Do NOT take GENVOYA if you:B (HBV) infection. GENVOYA • Worsening of hepatitis Ž • Take a medicine thattocontains: alfuzosin ), HIV-1 is not approved treat HBV. If you(Uroxatral have both Ž Ž Ž carbamazepine (Carbatrol , Epitol , Equetro , Tegretol , and HBV and stop taking GENVOYA, your HBV Žmay Ž Ž Tegretol-XR , Teril ), cisapride (Propulsid , Propulsid suddenly Žget worse. Do not stop taking GENVOYA Ž Quicksolv ), dihydroergotamine (D.H.E. 45Ž, MigranalŽ), YKVJQWV ƂTUV VCNMKPI VQ [QWT JGCNVJECTG RTQXKFGT CU VJG[ Ž Ž ergotamine (Cafergot , Migergot , ErgostatŽ, Medihaler will need to monitor your health. ErgotamineŽ, WigraineŽ, WigrettesŽ), lovastatin (AdvicorŽ, Ž Ž Altoprev , Mevacor ), lurasidone (LatudaŽ), methylergonovine Who should not take GENVOYA?

(ErgotrateÂŽ, MethergineÂŽ), midazolam (when taken by mouth),

Do not take GENVOYA if you take: phenobarbital (LuminalŽ), phenytoin (DilantinŽ, PhenytekŽ), •pimozide Certain(Orap prescription for other conditions. Ž Ž Ž ), rifampinmedicines (RifadinŽ, Rifamate , Rifater , It is important to askwhen yourused healthcare provider or Ž Rimactane ), sildenafil for lung problems pharmacist about medicines that should be taken Ž Ž Ž (Revatio ), simvastatin (SimcorŽ, Vytorin , Zocornot ), or with GENVOYA. triazolam (HalcionŽ).Do not start a new medicine without telling your healthcare provider. • Take the herbal supplement St. John’s wort. • The herbal supplement St. John’s wort. • Take any other HIV-1 medicines at the same time. • Any other medicines to treat HIV-1 infection. What are the other possible side effects GET MORE INFORMATION of GENVOYA? side effects of GENVOYA may also include: •Serious This is only a brief summary of important information about

•GENVOYA. Changes in your immune system. Yourorimmune Talk to your healthcare provider pharmacist toU[UVGO OC[ IGV UVTQPIGT CPF DGIKP VQ ƂIJV KPHGEVKQPU learn more. Telltoyour healthcare or provider if you have any new • Go GENVOYA.com call 1-800-GILEAD-5 symptoms after you start taking GENVOYA. •

If you need help paying for your medicine, visit GENVOYA. com for program information.

This is only a brief summary of important information about GENVOYAÂŽ and does not replace talking to your healthcare provider • Kidney problems, including kidneyabout failure.your Your condition and your treatment. healthcare provider should do blood and urine tests to check your kidneys. If you develop new or worse kidney problems, they may tell you to stop taking GENVOYA. SIDE acid EFFECTS OF GENVOYA •POSSIBLE Too much lactic in your blood (lactic acidosis), which is a serious but rare medical emergency that can GENVOYA can cause serious side effects, including: lead to death. Tell your healthcare provider right away if •you Those the “Most Important Information Aboutmore tired getinthese symptoms: weakness or being GENVOYAâ€? section.muscle pain, being short of breath or than usual, unusual breathing, stomach with nausea and vomiting, •fast Changes in your immunepain system. cold or blue hands and feet, feel dizzy orkidney lightheaded, • New or worse kidney problems, including failure. or a fast or abnormal heartbeat. • Too much lactic acid in your blood (lactic acidosis), which • Severe liver problems, which in rare cases can is a serious but rare emergencyprovider that can lead to lead to death. Tell medical your healthcare right death. provider right away if you get these away if Tell youyour gethealthcare these symptoms: skin or the white symptoms: or yellow, being more tired than usual, unusual part of yourweakness eyes turns dark “tea-coloredâ€? muscle pain, being short of breath fast breathing, stomach urine, light-colored stools, loss oforappetite for several pain or with nauseanausea, and vomiting, cold or blue hands days longer, or stomach-area pain.and feet, dizzycommon or lightheaded, a fastof or GENVOYA abnormal heartbeat. is nausea. Thefeel most side or effect • Severe Tell your healthcare provider if you have any sidetoeffects liver problems, which in rare cases can lead death. thatTell bother you or don’t go away. your healthcare provider right away if you get these symptoms: skin or the white part of your eyes turns yellow,

What I tell my healthcare provider before darkshould “tea-coloredâ€? urine, light-colored stools, loss of appetite taking GENVOYA? for several days or longer, nausea, or stomach-area pain. •The All most your common health problems. Beofsure to tell your side effect GENVOYA is nausea. healthcare provider if you have or have had any kidney These are not all the possible side effects of GENVOYA. or liver problems, including hepatitis virus infection. Tell your healthcare provider right away if you have any new •symptoms All the medicines take, including prescription while takingyou GENVOYA. and over-the-counter medicines, vitamins, and herbal Your healthcareOther provider will needmay to doaffect testshow to monitor supplements. medicines your health before and during treatment with GENVOYA. GENVOYA works. Keep a list of all your medicines and show it to your healthcare provider and pharmacist. Ask your healthcare provider if it is safe to take BEFORE TAKING GENVOYA GENVOYA with all of your other medicines. •Tell If you take antacids. Take antacids your healthcare provider if you: at least 2 hours before or after you take GENVOYA. • Have or have had any kidney or liver problems, including • Ifhepatitis you areinfection. pregnant or plan to become pregnant. It is not known if GENVOYA can harm your unborn baby. • Have any other medical condition. Tell your healthcare provider if you become pregnant •while Are pregnant or plan to become pregnant. taking GENVOYA. breastfeeding (nursing) (nursing) or plan to or breastfeed. • •IfAre you are breastfeeding plan to Do not breastfeed ifDo younot have HIV-1 because the risk of passing breastfeed. breastfeed. HIV-1ofcan be passed to yourinbaby. toHIV-1 the baby breast milk. Tellare your healthcare to provider all the medicines You encouraged reportabout negative side you take: effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, call 1-800-FDA-1088. • Keep a list that includes all or prescription and over-thecounter medicines, vitamins, and herbal supplements, and

Please Facts about and GENVOYA, showsee it toImportant your healthcare provider pharmacist. including important the following • Ask your healthcarewarnings, provider or on pharmacist about page. medicines that should not be taken with GENVOYA.

HOW TO TAKE GENVOYA

• GENVOYA is a complete one pill, once a day HIV-1 medicine. Ask your healthcare provider if GENVOYA is right for you. • Take GENVOYA with food.

GENVOYA.com

GENVOYA, the GENVOYA Logo, LOVE WHAT’S INSIDE, SHOW YOUR POWER, GILEAD, and the GILEAD Logo are trademarks of Gilead Sciences, Inc., or its related companies. All other marks referenced herein are the property of their respective owners. Version date: April 2017 Š 2017 Gilead Sciences, Inc. All rights reserved. GENC0141 04/17




Here’s to settling down and never giving up.

Let’s Grow Old Together See what life with HIV looks like from diagnosis through grandkids with a little help from Walgreens. Meet Peter and Kathleen and hear their story at Walgreens.com/LetsGrowOldTogether. ©2017 Walgreen Co. All rights reserved.

480171-209

0517






YOU MATTER AND SO DOES YOUR HEALTH That’s why starting and staying on HIV-1 treatment is so important. WHAT IS DESCOVYŽ? DESCOVY is a prescription medicine that is used together with other HIV-1 medicines to treat HIV-1 in people 12 years and older. DESCOVY is not for use to help reduce the risk of getting HIV-1 infection. DESCOVY combines 2 medicines into 1 pill taken once a day. Because DESCOVY by itself is not a complete treatment for HIV-1, it must be used together with other HIV-1 medicines.

DESCOVY does not cure HIV-1 infection or AIDS. To control HIV-1 infection and decrease HIV-related illnesses, you must keep taking DESCOVY. Ask your healthcare provider if you have questions about how to reduce the risk of passing HIV-1 to others. Always practice safer sex and use condoms to lower the chance QH UGZWCN EQPVCEV YKVJ DQF[ ĆƒWKFU 0GXGT TGWUG QT UJCTG PGGFNGU QT QVJGT KVGOU VJCV JCXG DQF[ ĆƒWKFU QP VJGO

IMPORTANT SAFETY INFORMATION What is the most important information I should know about DESCOVY? DESCOVY may cause serious side effects: • Worsening of hepatitis B (HBV) infection. DESCOVY is not approved to treat HBV. If you have both HIV-1 and HBV and stop taking DESCOVY, your HBV may suddenly get worse. Do not stop taking DESCOVY YKVJQWV ƂTUV VCNMKPI VQ [QWT JGCNVJECTG RTQXKFGT CU they will need to monitor your health. What are the other possible side effects of DESCOVY? Serious side effects of DESCOVY may also include: • Changes in your immune system. Your immune U[UVGO OC[ IGV UVTQPIGT CPF DGIKP VQ ƂIJV KPHGEVKQPU Tell your healthcare provider if you have any new symptoms after you start taking DESCOVY. • Kidney problems, including kidney failure. Your healthcare provider should do blood and urine tests to check your kidneys. Your healthcare provider may tell you to stop taking DESCOVY if you develop new or worse kidney problems. • Too much lactic acid in your blood (lactic acidosis), which is a serious but rare medical emergency that can lead to death. Tell your healthcare provider right away if you get these symptoms: weakness or being

more tired than usual, unusual muscle pain, being short of breath or fast breathing, stomach pain with nausea and vomiting, cold or blue hands and feet, feel dizzy or lightheaded, or a fast or abnormal heartbeat. • Severe liver problems, which in rare cases can lead to death. Tell your healthcare provider right away if you get these symptoms: skin or the white part of your eyes turns yellow, dark “tea-coloredâ€? urine, light-colored stools, loss of appetite for several days or longer, nausea, or stomach-area pain. • Bone problems, such as bone pain, softening, or thinning, which may lead to fractures. Your healthcare provider may do tests to check your bones. The most common side effect of DESCOVY is nausea. Tell your healthcare provider if you have any side effects that bother you or don’t go away. What should I tell my healthcare provider before taking DESCOVY? • All your health problems. Be sure to tell your healthcare provider if you have or have had any kidney, bone, or liver problems, including hepatitis virus infection. • All the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Other medicines may affect how DESCOVY works. Keep a list of all your medicines and show it to your healthcare provider and pharmacist. Ask your healthcare provider if it is safe to take DESCOVY with all of your other medicines. • If you are pregnant or plan to become pregnant. It is not known if DESCOVY can harm your unborn baby. Tell your healthcare provider if you become pregnant while taking DESCOVY. • If you are breastfeeding (nursing) or plan to breastfeed. Do not breastfeed. HIV-1 can be passed to the baby in breast milk. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Please see Important Facts about DESCOVY, including important warnings, on the following page.

Ask your healthcare provider if an HIV-1 treatment that contains DESCOVYÂŽ is right for you.



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GET MORE INFORMATION � ;OPZ PZ VUS` H IYPLM Z\TTHY` VM PTWVY[HU[ PUMVYTH[PVU HIV\[ +,:*6=@ ;HSR [V `V\Y OLHS[OJHYL WYV]PKLY VY pharmacist to learn more. � .V [V +,:*6=@ JVT VY JHSS .03,(+ � 0M `V\ ULLK OLSW WH`PUN MVY `V\Y TLKPJPUL ]PZP[ DESCOVY.com for program information.

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DESCOVY, the DESCOVY Logo, LOVE WHAT’S INSIDE, GILEAD, and the GILEAD Logo are trademarks of Gilead Sciences, Inc., or its related companies. All other marks referenced herein are the property of their respective owners. Version date: April 2017 © 2017 Gilead Sciences, Inc. All rights reserved. DVYC0057 05/17




Call for Nominations! Early Deadline: August st 25 5

8TH Annual

POZ 100 CELEBRATING N NG

Women POZ is seeking nominations for the 2017 POZ 100. This year’s list will celebrate both women living with HIV and those who are HIV negative making S a difference in the fight against HIV/AIDS fro ross the country. from across ab sh in 20 s Established 2010, the POZ 100 recognizes vi als a and organizations zatio committed tted individuals o en g the he HIV/AIDS S epidemic. id to ending

Don’t delay! Submit your nomination for the 2017 POZ 100 today!

fo mation and nd d to t submit a nomination n mination (self-nominations elff-nominations at For more information are accepted a d go to POZ.com/nominate. P Z om/ te accepted),


















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