MediWales LifeStories Magazine 2021

Page 53

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The world’s first ingestible supplement to help manage eczema and dry skin

According to the ‘Global Burden of Disease’ study, eczema is the leading contributor of all skinrelated disabilities, affecting up to 2-4% of the global population. The recent encouragement of frequent handwashing, wearing of masks and prolonged use of personal protective equipment has further increased the frequency and severity of eczema across the general population. A recent study showed that hand eczema tripled in young children during Spring 2020, when mandatory hand hygiene regimens were in force. Dr Neil Gibbs FRSB, renowned skin biologist, has worked in the dermatology sector for over 40 years. He is the inventor and entrepreneur behind pellamex, the world’s first skincare supplement formulated for sensitive and eczemaprone skin, designed to feed the skin barrier protein, filaggrin. The journey to develop pellamex began after a landmark paper was published that identified filaggrin as a significant factor in causes of eczema. Dr Gibbs then researched and clinically validated the ‘filaggrin feeding’ technology at the University of Manchester Dermatology Centre and launched pellamex.

The first of its kind in the global market, pellamex offers an alternative way for patients to take back control of their skin. With a unique patented formula, combining a high purity amino acid with other key EFSA-approved skin nutrients such as zinc, biotin, vitamins B2, B3 and E. It works with the skin’s biology to strengthen and restore the skin barrier. The active ingredient, l-histidine, is a natural amino acid that acts as a key building block for filaggrin, which eventually gets broken down into natural moisturising factor (NMF) in the epidermis, ultimately hydrating the skin from the inside.

Filaggrin is important in maintaining a normal healthy skin barrier, which we all need in an increasingly polluted world, but especially those with dry, sensitive and eczema prone skin. When filaggrin fails, the skin barrier is disrupted and this can lead to dry skin, irritation and atopic dermatitis. Research has shown that the pellamex active ingredient helps skin cells to make filaggrin and, unlike creams and lotions,

reaches the entire skin area, helping to block the entry of irritants and allergens and retain essential hydration. Pellamex’s technology has been assessed in a randomised, double blind placebocontrolled study in both adults and children with atopic dermatitis, who saw a 40% and 49% improvement in their skin respectively over the study period. “This is the largest effect of any treatment affecting the skin barrier in atopic dermatitis that I have seen in a clinical trial. Seriously impressive effects.”

A commenting on the adult study by: Professor Mike Cork Professor of Dermatology University of Sheffield

The daily 25ml dose comes in a portable sachet and can be consumed straight away or dissolved into water for a refreshing drink. A one-month supply (30 sachets) costs £49.99 and is available from www. pellamex.com or through subscription saving 15% per box (minimum six months).

www.pellamex.com

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Articles inside

Supporting the research response to COVID-19: The COPE Cymru study

2min
pages 72-73

Researchers venture into Covid hotspots to recruit patients for unique study

5min
pages 70-71

Study into antibiotic use wins research paper of the year prize

3min
page 69

€1.5 million project aims to work with 3,000 women to study impact of sex hormone changes on mental health

1min
page 67

How HCEC collaborates to innovate and translate valuable research into practice for patient and public benefit

4min
page 66

Projects developing the next generation of cancer therapeutics

2min
page 68

Achieving the remarkable: supporting and delivering COVID-19 research in Wales

3min
pages 64-65

New investment in the Life Sciences Research Network Wales

2min
page 63

Customised knee implant pioneered by TOKA®, Accelerate and Cardiff University Biomechanics Research Facility

2min
page 62

Design Studio Services help Cortigenix commercialise a new test providing early warning of potential health and fertilify issues

3min
pages 60-61

Taking science to Westminster Welsh biotech firm secures further investment for next-generation cancer therapies

2min
page 58

Harnessing technology to clear the surgical backlog

2min
page 56

Consult Smartly: reducing the outpatient waiting list backlog

3min
page 55

Space2B at The Maltings

1min
page 57

The world’s first ingestible supplement to help manage eczema and dry skin

2min
page 53

RedKnight helps secure grant for med-tech start-up’s rapid COVID-19 diagnostic

2min
page 54

Audit by a data protection authority How does it work?

2min
page 52

NHS and industry collaborate to improve compression garments

2min
page 50

Pandemic musings from Greaves Brewster

4min
page 49

Redefining the field of flexible endoscopy

2min
page 46

Business growth for Cryo Storage Solutions

1min
page 47

Bollé forms partnership with Welsh manufacturer

3min
pages 44-45

Evolve Raybotix UV-C Disinfection Robots at Techniquest

2min
page 48

High quality PPE masks: Made in the UK for the UK

2min
page 42

Blue Stream Academy - Supporting the health and care sector throughout the pandemic and beyond

2min
page 43

Keeping patients safe int he community using a portable 6 lead ECG device

2min
page 41

Facilitating advanced therapies by streamlining the value chain

2min
page 40

Bringing multimodal AI to healthcare

2min
page 38

PCI Pharma’s game-changing digital platform

3min
page 39

Developing breath analysis into a rapid diagnostic

2min
page 37

Safe endoscopy starts with the SNAP Endoscope Guide

2min
pages 32-33

Investment in sustainable manufacturing initiatives

2min
page 36

Scale-up for medical device contract manufacturing in Cardiff

3min
pages 34-35

SolasCure announces £15m Series A raise

2min
page 31

Cytiva: the life sciences company opening a new factory in Cardiff

3min
pages 28-30

Abel + Imray: 150 years protecting ideas

2min
page 27

Celtic connections turn brilliant ideas into practical reality

2min
page 26

Swansea University Academies driving global healthcare transformation

8min
pages 21-25

Respiratory Innovation Wales

3min
page 18

Talking Type 1: Books to support psychological needs of people living with diabetes

2min
page 20

Health Technology Wales

1min
page 19

Innovation that matters: Working with the NHS to improve pregnancy care

3min
page 16

Award winning SBRI Centre of Excellence goes from strength to strength

3min
page 17

Why digital technology is now more important than ever for healthcare in Wales

4min
page 15

Video consulting in NHS Wales rated highly by patients and clinicians

2min
page 13

Digital Health and Care Wales: Technology at the heart of NHS Wales’ response to the pandemic

3min
page 14

Journey to joint QMS accreditation for manufacture of medical devices in two NHS Wales services

2min
page 12

Introducing a locally designed electronic ureteric stent register

4min
page 9

Helping people with mental health problems to find and remain in work

4min
pages 10-11

TriTech Institute supports the development of new healthcare solutions

3min
page 7

Innovative digital bike to encourage exercise

1min
page 8

Velindre Cancer Centre in fluorouracil based chemotherapy genetic screening first

2min
page 6
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