Health Check issue 4

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ISSUE 4 P U B L I C A T I O N

Wednesday, May 28, 2014

SCIENTIFIC DISCOVERY CONTRIBUTES TO THE CONTROL OF THE CORONA VIRUS QATARI- DUTCH RESEARCH MANAGED TO ISOLATE THE VIRUS, MAKING IT POSSIBLE FOR SCIENTISTS TO STUDY ITS PROPERTIES

EDUCATIONAL HEALTH SUPPLEMENT SPONSORED BY

NEW DRUG COULD BOOST DIABETICS’ INSULIN LEVELS NATURALLY

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ype 2 diabetes, the most common kind, results from too little insulin in the bloodstream, leading to high blood sugar levels and a host of other health problems. The disease is growing in prevalence and is intensive to manage—many diabetics do daily insulin injections and blood sugar testing—with fatal consequences if it’s left out of control. Now scientists have opened the doorway to a new approach to diabetes treatment—rather than boosting insulin supply, instead slowing its disappearance—with the discovery of a molecule that inhibits insulin’s degradation. The discovery could bring new therapeutic treatments for diabetics.

Controlling Sugars

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s a part of Qatar’s efforts to combat Corona, a Qatari- Dutch research team had announced some time ago, that they were able to isolate and grow the virus “ Corona “ that causes Middle East Respiratory Syndrome , stressing that this is a scientific discovery which has been achieved in collaboration with the World Health Organisation. This will further contribute to the knowledge of the properties of the virus, enable scientists to promote measures for the prevention and control of the disease; in addition to the development of diagnostic tools and production of vaccines and treatment for the virus. Based on the recommendations of the World Health Organisation, there will be at the end of this month, for the first time in the world “national studies and surveys” conducted to know the risk factors of infection by this disease and to identify the source of the virus. The surveys will include animals and those working with them. The results of these surveys will be announced as soon as they are done. The Supreme Council of Health said that the cooperation with the Dutch reference laboratories yielded in matching laboratory results and virus detection with the techniques of Polymerisation Chain Reaction ( PCR), which makes the laboratory one of the first laboratories in the Middle East to diagnose the virus, “ Corona “ in the animal. The Supreme Council of Health cautioned persons who suffer from risk factors , diseases such as chronic or immune deficiencies , from dealing or mixing with animals, when visiting farms or barns, which information indicates the possibility of circulating the virus in, and to adhere to measures of hygiene and care to wash hands regularly before and after touching animals, to avoid friction with diseased animals and to follow food safety practices .

In the recent study scientists focused on the behaviour of insulin-degrading enzyme (IDE), which, as its name implies, breaks down insulin. Because in type 2 diabetes insulin levels are too low, blocking IDE has been a therapeutic approach of interest in treating the disease. Researchers sifted through more than 13,000 potential candidate molecules to find one, called 6bK, that bound to mouse IDE in a test tube. They then put 6bK to the test in live mice, some obese and some lean. The mice were given injections of the enzyme inhibitor and then an oral dose of glucose, simulating the sugar spike experienced after eating a meal. The mice treated with 6bK showed increased insulin levels and improved glucose clearance, both of which are problems for diabetics.

Future Treatments The findings, researchers say, firmly establish IDE as a target of exploration among diabetes therapies. Researchers speculate that pre-meal medications that block IDE, rather than chronic treatments, could be developed based on the evidence presented in their study. With a target firmly planted on the infamous enzyme, future studies can take aim at finding new ways to help a large percentage of the population living with diabetes.

CORONA VIRUS THAT CAUSES MIDDLE EAST RESPIRATORY SYNDROME - MERS-COV

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HE SHEIKH DR. MOHAMMED BIN HAMAD AL THANI

is Excellency Sheikh Dr. Mohammed bin Hamad Al Thani, Director of Public Health Department at the Supreme Council of Health, said that the Council is closely following developments in Corona virus after it moved to several neighbouring countries, stressing that the health status is safe and reassuring, and the State of Qatar has a very high readiness to deal with any suspected case or infection. The Director of the Public Health Department at the Supreme Council of Health, assured the citizens that there is no reason to their apprehensions so far, pointing out that the Supreme Council of Health is in touch with brothers in neighbouring countries to stand on all the devel-

opments and the developments of the infections, to take the necessary precautions about them. The Supreme Council of Health has confirmed that it is following through field visits the preventive measures and precautions in hospitals and health centres, pointing out that it is intensifying its activities to raise awareness among all members of the Qatari community and inform them of the developments related to Corona viruses and methods of prevention , as the Council implements an intensive awareness campaign, which includes various media and social networking sites, in addition to awareness publications in several languages about Corona viruses. (Continued on page 3)


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